reg-snw-30968

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.435	1.54e-08	9.13e-03	8.03e-03

chia-screen-data-Fav-reg-snw-30968 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
EIF2B3	8891	8	-2.546	2.435	4	-	Yes	Yes
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
COPS3	8533	8	-1.873	2.435	79	TF	-	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
[ STOML2 ]	30968	1	-1.394	2.435	18	-	-	-

Interactions (4)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
COPS3	8533	STOML2	30968	pd	>	reg.ITFP.txt: no annot
GPS1	2873	STOML2	30968	pd	>	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
COPS3	8533	EIF2B3	8891	pd	>	reg.ITFP.txt: no annot

Related GO terms (76)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0008180	COP9 signalosome	1.30e-07	1.27e-03	7.931	3	6	24
GO:0010388	cullin deneddylation	5.87e-06	5.73e-02	8.931	2	4	8
GO:1900210	positive regulation of cardiolipin metabolic process	5.12e-04	1.00e+00	10.931	1	1	1
GO:0010876	lipid localization	5.12e-04	1.00e+00	10.931	1	1	1
GO:0090297	positive regulation of mitochondrial DNA replication	5.12e-04	1.00e+00	10.931	1	1	1
GO:1990046	stress-induced mitochondrial fusion	5.12e-04	1.00e+00	10.931	1	1	1
GO:1901612	cardiolipin binding	1.02e-03	1.00e+00	9.931	1	1	2
GO:0010918	positive regulation of mitochondrial membrane potential	1.02e-03	1.00e+00	9.931	1	1	2
GO:0051716	cellular response to stimulus	1.02e-03	1.00e+00	9.931	1	1	2
GO:0034982	mitochondrial protein processing	1.02e-03	1.00e+00	9.931	1	1	2
GO:0035710	CD4-positive, alpha-beta T cell activation	1.02e-03	1.00e+00	9.931	1	1	2
GO:0032623	interleukin-2 production	1.02e-03	1.00e+00	9.931	1	1	2
GO:0006851	mitochondrial calcium ion transport	1.54e-03	1.00e+00	9.347	1	1	3
GO:0032057	negative regulation of translational initiation in response to stress	2.05e-03	1.00e+00	8.931	1	1	4
GO:0005851	eukaryotic translation initiation factor 2B complex	2.05e-03	1.00e+00	8.931	1	2	4
GO:0016779	nucleotidyltransferase activity	2.05e-03	1.00e+00	8.931	1	1	4
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	2.56e-03	1.00e+00	8.610	1	1	5
GO:0050847	progesterone receptor signaling pathway	3.07e-03	1.00e+00	8.347	1	2	6
GO:0005743	mitochondrial inner membrane	3.89e-03	1.00e+00	4.309	2	9	197
GO:0010944	negative regulation of transcription by competitive promoter binding	4.09e-03	1.00e+00	7.931	1	1	8
GO:0071354	cellular response to interleukin-6	4.60e-03	1.00e+00	7.762	1	1	9
GO:0005095	GTPase inhibitor activity	5.11e-03	1.00e+00	7.610	1	1	10
GO:0009416	response to light stimulus	5.11e-03	1.00e+00	7.610	1	1	10
GO:0060766	negative regulation of androgen receptor signaling pathway	5.62e-03	1.00e+00	7.472	1	4	11
GO:0042776	mitochondrial ATP synthesis coupled proton transport	5.62e-03	1.00e+00	7.472	1	2	11
GO:0042101	T cell receptor complex	5.62e-03	1.00e+00	7.472	1	1	11
GO:0019897	extrinsic component of plasma membrane	7.15e-03	1.00e+00	7.124	1	1	14
GO:0016575	histone deacetylation	7.15e-03	1.00e+00	7.124	1	2	14
GO:0000188	inactivation of MAPK activity	7.66e-03	1.00e+00	7.025	1	1	15
GO:0014003	oligodendrocyte development	7.66e-03	1.00e+00	7.025	1	1	15
GO:0008135	translation factor activity, nucleic acid binding	7.66e-03	1.00e+00	7.025	1	4	15
GO:0071897	DNA biosynthetic process	1.02e-02	1.00e+00	6.610	1	2	20
GO:0001772	immunological synapse	1.17e-02	1.00e+00	6.408	1	2	23
GO:0005515	protein binding	1.34e-02	1.00e+00	1.244	5	198	4124
GO:0007005	mitochondrion organization	1.43e-02	1.00e+00	6.124	1	2	28
GO:0051259	protein oligomerization	1.48e-02	1.00e+00	6.073	1	3	29
GO:0009408	response to heat	1.58e-02	1.00e+00	5.977	1	1	31
GO:0007254	JNK cascade	1.73e-02	1.00e+00	5.844	1	1	34
GO:0043434	response to peptide hormone	1.83e-02	1.00e+00	5.762	1	1	36
GO:0003743	translation initiation factor activity	1.88e-02	1.00e+00	5.722	1	8	37
GO:0005737	cytoplasm	2.07e-02	1.00e+00	1.569	4	127	2633
GO:0005085	guanyl-nucleotide exchange factor activity	2.18e-02	1.00e+00	5.505	1	2	43
GO:0009749	response to glucose	2.28e-02	1.00e+00	5.440	1	1	45
GO:0005758	mitochondrial intermembrane space	2.43e-02	1.00e+00	5.347	1	4	48
GO:0006874	cellular calcium ion homeostasis	2.89e-02	1.00e+00	5.099	1	3	57
GO:0042826	histone deacetylase binding	2.94e-02	1.00e+00	5.073	1	5	58
GO:0050852	T cell receptor signaling pathway	3.43e-02	1.00e+00	4.844	1	2	68
GO:0007165	signal transduction	3.52e-02	1.00e+00	2.660	2	24	618
GO:0030308	negative regulation of cell growth	3.53e-02	1.00e+00	4.802	1	3	70
GO:0001649	osteoblast differentiation	3.73e-02	1.00e+00	4.722	1	5	74
GO:0006413	translational initiation	4.97e-02	1.00e+00	4.302	1	6	99
GO:0043547	positive regulation of GTPase activity	5.61e-02	1.00e+00	4.124	1	2	112
GO:0042981	regulation of apoptotic process	5.61e-02	1.00e+00	4.124	1	4	112
GO:0007049	cell cycle	5.75e-02	1.00e+00	4.086	1	8	115
GO:0045121	membrane raft	6.19e-02	1.00e+00	3.977	1	1	124
GO:0015629	actin cytoskeleton	6.77e-02	1.00e+00	3.844	1	5	136
GO:0044212	transcription regulatory region DNA binding	7.11e-02	1.00e+00	3.772	1	13	143
GO:0001701	in utero embryonic development	7.64e-02	1.00e+00	3.665	1	7	154
GO:0005102	receptor binding	8.60e-02	1.00e+00	3.489	1	3	174
GO:0006412	translation	8.79e-02	1.00e+00	3.456	1	12	178
GO:0005856	cytoskeleton	9.36e-02	1.00e+00	3.362	1	8	190
GO:0019899	enzyme binding	1.03e-01	1.00e+00	3.217	1	7	210
GO:0008285	negative regulation of cell proliferation	1.34e-01	1.00e+00	2.818	1	11	277
GO:0045892	negative regulation of transcription, DNA-templated	1.52e-01	1.00e+00	2.623	1	17	317
GO:0044267	cellular protein metabolic process	1.68e-01	1.00e+00	2.472	1	14	352
GO:0045893	positive regulation of transcription, DNA-templated	1.79e-01	1.00e+00	2.373	1	21	377
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.13e-01	1.00e+00	2.099	1	29	456
GO:0010467	gene expression	2.46e-01	1.00e+00	1.868	1	49	535
GO:0005887	integral component of plasma membrane	2.62e-01	1.00e+00	1.764	1	8	575
GO:0005739	mitochondrion	2.95e-01	1.00e+00	1.567	1	32	659
GO:0006355	regulation of transcription, DNA-templated	3.16e-01	1.00e+00	1.450	1	31	715
GO:0005654	nucleoplasm	3.75e-01	1.00e+00	1.157	1	68	876
GO:0016020	membrane	4.83e-01	1.00e+00	0.694	1	56	1207
GO:0005634	nucleus	5.37e-01	1.00e+00	0.267	2	158	3246
GO:0070062	extracellular vesicular exosome	6.02e-01	1.00e+00	0.251	1	51	1641
GO:0005829	cytosol	6.36e-01	1.00e+00	0.128	1	88	1787

chia-Fav

reg-snw-30968

Statistics

Genes (5)

Interactions (4)

Related GO terms (76)