reg-snw-23254

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.340	5.26e-08	1.87e-02	1.52e-02

chia-screen-data-Fav-reg-snw-23254 subnetwork

Genes (6)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
VWF	7450	4	-2.381	2.340	58	TF	Yes	Yes
BCL6B	255877	3	-2.723	2.340	9	TF	Yes	Yes
SYF2	25949	2	-2.449	2.340	4	-	Yes	-
GATA2	2624	2	-1.645	2.340	126	TF	-	-
[ KAZN ]	23254	1	-1.044	2.340	8	-	-	-
PRDM14	63978	7	-3.797	2.412	147	TF	Yes	Yes

Interactions (5)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
GATA2	2624	VWF	7450	pd	>	reg.TRANSFAC.txt: no annot
GATA2	2624	SYF2	25949	pd	>	reg.pazar.txt: no annot
KAZN	23254	PRDM14	63978	pd	<	reg.pazar.txt: no annot
GATA2	2624	KAZN	23254	pd	>	reg.pazar.txt: no annot
VWF	7450	BCL6B	255877	pd	<>	reg.ITFP.txt: no annot

Related GO terms (99)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0048873	homeostasis of number of cells within a tissue	2.85e-05	2.79e-01	7.861	2	2	14
GO:0034972	histone H3-R26 methylation	6.14e-04	1.00e+00	10.668	1	1	1
GO:0097154	GABAergic neuron differentiation	6.14e-04	1.00e+00	10.668	1	1	1
GO:2000977	regulation of forebrain neuron differentiation	6.14e-04	1.00e+00	10.668	1	1	1
GO:0060872	semicircular canal development	6.14e-04	1.00e+00	10.668	1	1	1
GO:0001827	inner cell mass cell fate commitment	6.14e-04	1.00e+00	10.668	1	1	1
GO:0019865	immunoglobulin binding	1.23e-03	1.00e+00	9.668	1	1	2
GO:0021514	ventral spinal cord interneuron differentiation	1.23e-03	1.00e+00	9.668	1	1	2
GO:0035854	eosinophil fate commitment	1.23e-03	1.00e+00	9.668	1	1	2
GO:0070345	negative regulation of fat cell proliferation	1.23e-03	1.00e+00	9.668	1	1	2
GO:0021533	cell differentiation in hindbrain	1.84e-03	1.00e+00	9.083	1	1	3
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	1.84e-03	1.00e+00	9.083	1	1	3
GO:0033093	Weibel-Palade body	2.46e-03	1.00e+00	8.668	1	1	4
GO:0044030	regulation of DNA methylation	2.46e-03	1.00e+00	8.668	1	1	4
GO:0007599	hemostasis	2.46e-03	1.00e+00	8.668	1	1	4
GO:0030718	germ-line stem cell maintenance	2.46e-03	1.00e+00	8.668	1	1	4
GO:0045654	positive regulation of megakaryocyte differentiation	3.07e-03	1.00e+00	8.347	1	1	5
GO:2000178	negative regulation of neural precursor cell proliferation	3.07e-03	1.00e+00	8.347	1	1	5
GO:0035065	regulation of histone acetylation	3.07e-03	1.00e+00	8.347	1	1	5
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	3.68e-03	1.00e+00	8.083	1	1	6
GO:0045650	negative regulation of macrophage differentiation	4.29e-03	1.00e+00	7.861	1	1	7
GO:0001655	urogenital system development	4.91e-03	1.00e+00	7.668	1	1	8
GO:0031091	platelet alpha granule	4.91e-03	1.00e+00	7.668	1	1	8
GO:0040029	regulation of gene expression, epigenetic	6.13e-03	1.00e+00	7.347	1	1	10
GO:0021954	central nervous system neuron development	6.13e-03	1.00e+00	7.347	1	1	10
GO:0045746	negative regulation of Notch signaling pathway	6.13e-03	1.00e+00	7.347	1	1	10
GO:0001709	cell fate determination	6.74e-03	1.00e+00	7.209	1	1	11
GO:0048568	embryonic organ development	6.74e-03	1.00e+00	7.209	1	1	11
GO:0007095	mitotic G2 DNA damage checkpoint	7.96e-03	1.00e+00	6.968	1	2	13
GO:0007597	blood coagulation, intrinsic pathway	7.96e-03	1.00e+00	6.968	1	2	13
GO:0060216	definitive hemopoiesis	7.96e-03	1.00e+00	6.968	1	1	13
GO:0001533	cornified envelope	7.96e-03	1.00e+00	6.968	1	1	13
GO:0031589	cell-substrate adhesion	7.96e-03	1.00e+00	6.968	1	1	13
GO:0001708	cell fate specification	9.18e-03	1.00e+00	6.762	1	1	15
GO:0030057	desmosome	9.18e-03	1.00e+00	6.762	1	2	15
GO:0001158	enhancer sequence-specific DNA binding	9.18e-03	1.00e+00	6.762	1	1	15
GO:0070742	C2H2 zinc finger domain binding	9.18e-03	1.00e+00	6.762	1	1	15
GO:0050766	positive regulation of phagocytosis	9.18e-03	1.00e+00	6.762	1	1	15
GO:0045648	positive regulation of erythrocyte differentiation	1.04e-02	1.00e+00	6.581	1	2	17
GO:0007369	gastrulation	1.04e-02	1.00e+00	6.581	1	2	17
GO:0009566	fertilization	1.10e-02	1.00e+00	6.499	1	1	18
GO:0001892	embryonic placenta development	1.22e-02	1.00e+00	6.347	1	1	20
GO:0006909	phagocytosis	1.34e-02	1.00e+00	6.209	1	1	22
GO:0021983	pituitary gland development	1.34e-02	1.00e+00	6.209	1	2	22
GO:0007281	germ cell development	1.34e-02	1.00e+00	6.209	1	1	22
GO:0031424	keratinization	1.41e-02	1.00e+00	6.145	1	2	23
GO:0001890	placenta development	1.59e-02	1.00e+00	5.968	1	2	26
GO:0007596	blood coagulation	1.64e-02	1.00e+00	3.263	2	13	339
GO:0005634	nucleus	1.76e-02	1.00e+00	1.326	5	158	3246
GO:0045599	negative regulation of fat cell differentiation	1.77e-02	1.00e+00	5.810	1	2	29
GO:0008168	methyltransferase activity	1.83e-02	1.00e+00	5.762	1	2	30
GO:0048469	cell maturation	1.89e-02	1.00e+00	5.714	1	1	31
GO:0035019	somatic stem cell maintenance	1.95e-02	1.00e+00	5.668	1	3	32
GO:0000902	cell morphogenesis	2.13e-02	1.00e+00	5.539	1	5	35
GO:0031093	platelet alpha granule lumen	2.13e-02	1.00e+00	5.539	1	3	35
GO:0042472	inner ear morphogenesis	2.25e-02	1.00e+00	5.459	1	1	37
GO:0001948	glycoprotein binding	2.25e-02	1.00e+00	5.459	1	1	37
GO:0009611	response to wounding	2.49e-02	1.00e+00	5.311	1	2	41
GO:0051087	chaperone binding	2.73e-02	1.00e+00	5.177	1	3	45
GO:0005518	collagen binding	2.85e-02	1.00e+00	5.114	1	2	47
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.88e-02	1.00e+00	2.836	2	29	456
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.97e-02	1.00e+00	5.054	1	4	49
GO:0002020	protease binding	3.03e-02	1.00e+00	5.025	1	3	50
GO:0071013	catalytic step 2 spliceosome	3.69e-02	1.00e+00	4.738	1	5	61
GO:0002576	platelet degranulation	3.75e-02	1.00e+00	4.714	1	3	62
GO:0047485	protein N-terminus binding	3.93e-02	1.00e+00	4.646	1	6	65
GO:0005178	integrin binding	4.11e-02	1.00e+00	4.581	1	3	68
GO:0001889	liver development	4.29e-02	1.00e+00	4.519	1	4	71
GO:0045766	positive regulation of angiogenesis	4.70e-02	1.00e+00	4.383	1	4	78
GO:0051260	protein homooligomerization	5.23e-02	1.00e+00	4.225	1	2	87
GO:0031012	extracellular matrix	6.40e-02	1.00e+00	3.927	1	4	107
GO:0005578	proteinaceous extracellular matrix	6.86e-02	1.00e+00	3.823	1	4	115
GO:0000398	mRNA splicing, via spliceosome	7.61e-02	1.00e+00	3.668	1	15	128
GO:0009897	external side of plasma membrane	7.79e-02	1.00e+00	3.635	1	3	131
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	7.84e-02	1.00e+00	3.624	1	4	132
GO:0030168	platelet activation	8.36e-02	1.00e+00	3.529	1	5	141
GO:0001701	in utero embryonic development	9.10e-02	1.00e+00	3.402	1	7	154
GO:0046872	metal ion binding	1.06e-01	1.00e+00	1.801	2	24	934
GO:0003677	DNA binding	1.08e-01	1.00e+00	1.781	2	52	947
GO:0043234	protein complex	1.22e-01	1.00e+00	2.954	1	13	210
GO:0008134	transcription factor binding	1.22e-01	1.00e+00	2.961	1	10	209
GO:0030198	extracellular matrix organization	1.28e-01	1.00e+00	2.881	1	7	221
GO:0006351	transcription, DNA-templated	1.35e-01	1.00e+00	1.597	2	47	1076
GO:0007155	cell adhesion	1.41e-01	1.00e+00	2.738	1	8	244
GO:0003682	chromatin binding	1.45e-01	1.00e+00	2.691	1	15	252
GO:0042802	identical protein binding	1.99e-01	1.00e+00	2.201	1	15	354
GO:0005783	endoplasmic reticulum	2.12e-01	1.00e+00	2.095	1	12	381
GO:0042803	protein homodimerization activity	2.36e-01	1.00e+00	1.927	1	13	428
GO:0003700	sequence-specific DNA binding transcription factor activity	3.08e-01	1.00e+00	1.484	1	22	582
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.36e-01	1.00e+00	1.338	1	29	644
GO:0005576	extracellular region	3.44e-01	1.00e+00	1.296	1	15	663
GO:0006355	regulation of transcription, DNA-templated	3.66e-01	1.00e+00	1.187	1	31	715
GO:0008270	zinc ion binding	3.71e-01	1.00e+00	1.163	1	39	727
GO:0044822	poly(A) RNA binding	4.01e-01	1.00e+00	1.026	1	45	799
GO:0005654	nucleoplasm	4.31e-01	1.00e+00	0.894	1	68	876
GO:0005515	protein binding	5.02e-01	1.00e+00	0.244	3	198	4124
GO:0005730	nucleolus	5.50e-01	1.00e+00	0.419	1	74	1217
GO:0070062	extracellular vesicular exosome	6.69e-01	1.00e+00	-0.012	1	51	1641
GO:0005737	cytoplasm	8.48e-01	1.00e+00	-0.694	1	127	2633

chia-Fav

reg-snw-23254

Statistics

Genes (6)

Interactions (5)

Related GO terms (99)