reg-snw-1586

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.229	2.04e-07	3.91e-02	2.99e-02

chia-screen-data-Fav-reg-snw-1586 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
NFIC	4782	2	-1.844	2.280	44	TF	-	-
[ CYP17A1 ]	1586	1	-1.524	2.229	8	-	-	-
C4A	720	1	-1.852	2.229	4	-	-	-
ACTA1	58	2	-2.128	2.280	11	-	Yes	-
PRDM14	63978	7	-3.797	2.412	147	TF	Yes	Yes

Interactions (4)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
NFIC	4782	PRDM14	63978	pd	<	reg.pazar.txt: no annot
CYP17A1	1586	NFIC	4782	pd	<	reg.pazar.txt: no annot; reg.oreganno.txt: no annot; reg.TRANSFAC.txt: no annot
C4A	720	NFIC	4782	pd	<	reg.TRANSFAC.txt: no annot
ACTA1	58	NFIC	4782	pd	<	reg.TRANSFAC.txt: no annot

Related GO terms (105)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0048545	response to steroid hormone	1.63e-05	1.59e-01	8.231	2	2	13
GO:0034972	histone H3-R26 methylation	5.12e-04	1.00e+00	10.931	1	1	1
GO:0004508	steroid 17-alpha-monooxygenase activity	5.12e-04	1.00e+00	10.931	1	1	1
GO:0001159	core promoter proximal region DNA binding	5.12e-04	1.00e+00	10.931	1	1	1
GO:0047442	17-alpha-hydroxyprogesterone aldolase activity	5.12e-04	1.00e+00	10.931	1	1	1
GO:0010034	response to acetate	5.12e-04	1.00e+00	10.931	1	1	1
GO:0001827	inner cell mass cell fate commitment	5.12e-04	1.00e+00	10.931	1	1	1
GO:0072562	blood microparticle	6.69e-04	1.00e+00	5.592	2	4	81
GO:0043503	skeletal muscle fiber adaptation	1.02e-03	1.00e+00	9.931	1	1	2
GO:0009991	response to extracellular stimulus	1.54e-03	1.00e+00	9.347	1	1	3
GO:0005865	striated muscle thin filament	1.54e-03	1.00e+00	9.347	1	1	3
GO:0090031	positive regulation of steroid hormone biosynthetic process	1.54e-03	1.00e+00	9.347	1	1	3
GO:0018894	dibenzo-p-dioxin metabolic process	2.05e-03	1.00e+00	8.931	1	1	4
GO:0018879	biphenyl metabolic process	2.05e-03	1.00e+00	8.931	1	1	4
GO:0030240	skeletal muscle thin filament assembly	2.05e-03	1.00e+00	8.931	1	1	4
GO:0018958	phenol-containing compound metabolic process	2.05e-03	1.00e+00	8.931	1	1	4
GO:2000427	positive regulation of apoptotic cell clearance	2.05e-03	1.00e+00	8.931	1	1	4
GO:0044030	regulation of DNA methylation	2.05e-03	1.00e+00	8.931	1	1	4
GO:0017085	response to insecticide	2.05e-03	1.00e+00	8.931	1	2	4
GO:0030718	germ-line stem cell maintenance	2.05e-03	1.00e+00	8.931	1	1	4
GO:0060992	response to fungicide	2.05e-03	1.00e+00	8.931	1	2	4
GO:0042448	progesterone metabolic process	2.56e-03	1.00e+00	8.610	1	1	5
GO:0009635	response to herbicide	2.56e-03	1.00e+00	8.610	1	1	5
GO:0051597	response to methylmercury	2.56e-03	1.00e+00	8.610	1	2	5
GO:0001849	complement component C1q binding	2.56e-03	1.00e+00	8.610	1	2	5
GO:0018963	phthalate metabolic process	2.56e-03	1.00e+00	8.610	1	1	5
GO:0042446	hormone biosynthetic process	3.07e-03	1.00e+00	8.347	1	1	6
GO:0030728	ovulation	3.07e-03	1.00e+00	8.347	1	1	6
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	3.07e-03	1.00e+00	8.347	1	1	6
GO:0006702	androgen biosynthetic process	4.09e-03	1.00e+00	7.931	1	1	8
GO:0006704	glucocorticoid biosynthetic process	4.09e-03	1.00e+00	7.931	1	1	8
GO:0010226	response to lithium ion	4.60e-03	1.00e+00	7.762	1	2	9
GO:0033327	Leydig cell differentiation	5.11e-03	1.00e+00	7.610	1	1	10
GO:0040029	regulation of gene expression, epigenetic	5.11e-03	1.00e+00	7.610	1	1	10
GO:0071236	cellular response to antibiotic	5.11e-03	1.00e+00	7.610	1	1	10
GO:0071371	cellular response to gonadotropin stimulus	5.62e-03	1.00e+00	7.472	1	1	11
GO:0048741	skeletal muscle fiber development	5.62e-03	1.00e+00	7.472	1	1	11
GO:0007548	sex differentiation	6.13e-03	1.00e+00	7.347	1	1	12
GO:0016125	sterol metabolic process	6.64e-03	1.00e+00	7.231	1	1	13
GO:0048873	homeostasis of number of cells within a tissue	7.15e-03	1.00e+00	7.124	1	2	14
GO:0030449	regulation of complement activation	7.15e-03	1.00e+00	7.124	1	2	14
GO:0001708	cell fate specification	7.66e-03	1.00e+00	7.025	1	1	15
GO:0006694	steroid biosynthetic process	7.66e-03	1.00e+00	7.025	1	1	15
GO:0017022	myosin binding	8.17e-03	1.00e+00	6.931	1	2	16
GO:0030325	adrenal gland development	8.68e-03	1.00e+00	6.844	1	1	17
GO:0031667	response to nutrient levels	8.68e-03	1.00e+00	6.844	1	2	17
GO:0009566	fertilization	9.18e-03	1.00e+00	6.762	1	1	18
GO:0030017	sarcomere	9.18e-03	1.00e+00	6.762	1	2	18
GO:0030049	muscle filament sliding	9.69e-03	1.00e+00	6.684	1	2	19
GO:0004866	endopeptidase inhibitor activity	9.69e-03	1.00e+00	6.684	1	1	19
GO:0006956	complement activation	1.02e-02	1.00e+00	6.610	1	2	20
GO:0043531	ADP binding	1.02e-02	1.00e+00	6.610	1	2	20
GO:0007281	germ cell development	1.12e-02	1.00e+00	6.472	1	1	22
GO:0006958	complement activation, classical pathway	1.38e-02	1.00e+00	6.177	1	3	27
GO:0005884	actin filament	1.38e-02	1.00e+00	6.177	1	1	27
GO:0019825	oxygen binding	1.43e-02	1.00e+00	6.124	1	1	28
GO:0008168	methyltransferase activity	1.53e-02	1.00e+00	6.025	1	2	30
GO:0010212	response to ionizing radiation	1.53e-02	1.00e+00	6.025	1	3	30
GO:0021766	hippocampus development	1.58e-02	1.00e+00	5.977	1	1	31
GO:0051591	response to cAMP	1.63e-02	1.00e+00	5.931	1	1	32
GO:0016049	cell growth	1.78e-02	1.00e+00	5.802	1	1	35
GO:0000902	cell morphogenesis	1.78e-02	1.00e+00	5.802	1	5	35
GO:0032526	response to retinoic acid	1.93e-02	1.00e+00	5.684	1	1	38
GO:0042475	odontogenesis of dentin-containing tooth	2.03e-02	1.00e+00	5.610	1	2	40
GO:0034097	response to cytokine	2.03e-02	1.00e+00	5.610	1	1	40
GO:0008202	steroid metabolic process	2.08e-02	1.00e+00	5.574	1	1	41
GO:0009612	response to mechanical stimulus	2.33e-02	1.00e+00	5.408	1	2	46
GO:0001725	stress fiber	2.33e-02	1.00e+00	5.408	1	6	46
GO:0006936	muscle contraction	2.74e-02	1.00e+00	5.177	1	5	54
GO:0071222	cellular response to lipopolysaccharide	3.23e-02	1.00e+00	4.931	1	2	64
GO:0005200	structural constituent of cytoskeleton	3.43e-02	1.00e+00	4.844	1	2	68
GO:0010951	negative regulation of endopeptidase activity	3.58e-02	1.00e+00	4.782	1	2	71
GO:0003690	double-stranded DNA binding	4.18e-02	1.00e+00	4.556	1	6	83
GO:0020037	heme binding	4.43e-02	1.00e+00	4.472	1	3	88
GO:0005506	iron ion binding	4.62e-02	1.00e+00	4.408	1	4	92
GO:0006260	DNA replication	4.72e-02	1.00e+00	4.377	1	9	94
GO:0006805	xenobiotic metabolic process	4.72e-02	1.00e+00	4.377	1	3	94
GO:0030424	axon	6.39e-02	1.00e+00	3.931	1	1	128
GO:0015629	actin cytoskeleton	6.77e-02	1.00e+00	3.844	1	5	136
GO:0043025	neuronal cell body	8.46e-02	1.00e+00	3.514	1	3	171
GO:0006954	inflammatory response	9.12e-02	1.00e+00	3.400	1	3	185
GO:0042493	response to drug	1.09e-01	1.00e+00	3.137	1	4	222
GO:0055114	oxidation-reduction process	1.48e-01	1.00e+00	2.665	1	9	308
GO:0006366	transcription from RNA polymerase II promoter	1.63e-01	1.00e+00	2.518	1	23	341
GO:0005783	endoplasmic reticulum	1.80e-01	1.00e+00	2.358	1	12	381
GO:0005789	endoplasmic reticulum membrane	1.83e-01	1.00e+00	2.335	1	7	387
GO:0070062	extracellular vesicular exosome	1.99e-01	1.00e+00	1.251	2	51	1641
GO:0045087	innate immune response	2.11e-01	1.00e+00	2.111	1	12	452
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.13e-01	1.00e+00	2.099	1	29	456
GO:0003700	sequence-specific DNA binding transcription factor activity	2.65e-01	1.00e+00	1.747	1	22	582
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	2.89e-01	1.00e+00	1.601	1	29	644
GO:0005615	extracellular space	2.92e-01	1.00e+00	1.585	1	15	651
GO:0005739	mitochondrion	2.95e-01	1.00e+00	1.567	1	32	659
GO:0005576	extracellular region	2.96e-01	1.00e+00	1.559	1	15	663
GO:0006355	regulation of transcription, DNA-templated	3.16e-01	1.00e+00	1.450	1	31	715
GO:0044281	small molecule metabolic process	3.64e-01	1.00e+00	1.210	1	35	844
GO:0005524	ATP binding	3.81e-01	1.00e+00	1.131	1	37	892
GO:0046872	metal ion binding	3.95e-01	1.00e+00	1.064	1	24	934
GO:0003677	DNA binding	4.00e-01	1.00e+00	1.044	1	52	947
GO:0006351	transcription, DNA-templated	4.42e-01	1.00e+00	0.860	1	47	1076
GO:0005730	nucleolus	4.86e-01	1.00e+00	0.682	1	74	1217
GO:0005634	nucleus	5.37e-01	1.00e+00	0.267	2	158	3246
GO:0005886	plasma membrane	6.35e-01	1.00e+00	0.131	1	46	1784
GO:0005829	cytosol	6.36e-01	1.00e+00	0.128	1	88	1787
GO:0005515	protein binding	7.01e-01	1.00e+00	-0.078	2	198	4124

chia-Fav

reg-snw-1586

Statistics

Genes (5)

Interactions (4)

Related GO terms (105)