meta-reg-snw-8562

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
int-snw-892 chia-screen-data-Fav 2.968 5.68e-17 8.94e-05 1.03e-03 17 15
reg-snw-8562 chia-screen-data-Fav 2.263 1.35e-07 3.15e-02 2.44e-02 32 24
int-snw-1029 chia-screen-data-Fav 2.959 7.22e-17 1.01e-04 1.12e-03 11 10
int-snw-6334 chia-screen-data-Fav 2.813 2.82e-15 6.25e-04 4.06e-03 16 14
chia-screen-data-Fav-meta-reg-snw-8562 subnetwork

Genes (55)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Chia-Hits Primary Chia-Hits Secondary
CCNC 892 2-1.7262.968101--
ANAPC5 51433 6-1.2642.263239--
CNOT1 23019 7-2.3472.263124Yes-
PHB2 11331 6-2.2362.994151Yes-
SCN8A 6334 3-1.1732.8135--
PHB 5245 12-2.7432.689163YesYes
MED28 80306 6-2.4042.44586Yes-
ICT1 3396 3-2.2102.813208Yes-
TIA1 7072 4-1.2342.26353--
CBLL1 79872 6-1.8972.44538--
MED13L 23389 8-2.5502.30750Yes-
VARS 7407 8-2.3662.689204Yes-
APC 324 6-2.2933.004384Yes-
POU5F1 5460 12-5.1483.538179YesYes
GSTP1 2950 3-2.2512.95559Yes-
MAPK14 1432 3-1.9022.955304--
FBXO22 26263 8-1.7392.459208--
DENR 8562 4-1.0232.26342--
E4F1 1877 3-2.3702.95927YesYes
PSMD2 5708 6-4.1723.157389YesYes
FOXJ3 22887 4-2.4072.36987YesYes
EIF2S2 8894 9-2.9992.459103YesYes
SUV39H2 79723 7-2.3072.41021YesYes
CASP2 835 4-2.0072.44547Yes-
MED12 9968 2-2.4653.20665Yes-
ETF1 2107 7-2.8292.50377YesYes
GTF3C3 9330 4-1.4502.42862--
NAP1L4 4676 2-1.9473.119187--
CCT7 10574 10-2.3352.459173Yes-
CPSF3 51692 7-2.6862.50331YesYes
HNRNPU 3192 12-2.8692.644172Yes-
CLASP1 23332 4-2.3652.45939Yes-
NDUFA4L2 56901 10-2.4772.45921Yes-
HCFC1 3054 2-2.9253.44971YesYes
MED19 219541 4-2.6573.449115Yes-
AGPS 8540 6-2.4242.41027YesYes
SLC7A5P1 81893 4-3.2172.4454Yes-
YAP1 10413 12-4.2563.53853Yes-
NCBP1 4686 8-2.5102.45984YesYes
SYNCRIP 10492 8-2.4012.503247YesYes
LUC7L3 51747 4-3.5233.44918Yes-
ZDHHC20 253832 4-2.6732.32625Yes-
TADA2B 93624 4-3.0613.08219Yes-
FTSJ1 24140 5-2.4632.689130YesYes
EIF2B2 8892 4-2.4622.96895YesYes
GSPT1 2935 7-2.3132.50347YesYes
SRSF3 6428 5-2.9923.53854Yes-
NFRKB 4798 3-3.1293.10833YesYes
YY1 7528 3-2.5723.120168YesYes
NOLC1 9221 5-1.9852.503136--
POLH 5429 8-2.5862.45924YesYes
BTRC 8945 4-1.1442.26364--
DDIT3 1649 11-2.8253.504343YesYes
CDKN2A 1029 3-1.7742.959126--
FUBP1 8880 6-2.4142.38941YesYes

Interactions (101)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
MAPK14 1432 DDIT3 1649 pp -- int.I2D: BCI, BioGrid, HPRD;
int.HPRD: in vitro
DENR 8562 CBLL1 79872 pd < reg.ITFP.txt: no annot
BTRC 8945 FOXJ3 22887 pd <> reg.ITFP.txt: no annot
ETF1 2107 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
MAPK14 1432 GSTP1 2950 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, BCI
TIA1 7072 CLASP1 23332 pd <> reg.ITFP.txt: no annot
APC 324 CCT7 10574 pp -- int.I2D: Jorgensen_EphR, SOURAV_MAPK_LOW, IntAct
EIF2B2 8892 TADA2B 93624 pp -- int.I2D: BioGrid_Fly, BIND_Fly, FlyLow, IntAct_Fly, MINT_Fly
APC 324 PHB 5245 pp -- int.I2D: Jorgensen_EphR
ETF1 2107 GSPT1 2935 pp -- int.I2D: MINT, BCI, BioGrid, HPRD;
int.Mint: MI:0915(physical association);
int.HPRD: in vivo, yeast 2-hybrid
CCNC 892 NAP1L4 4676 pp -- int.I2D: BioGrid_Yeast
ICT1 3396 PHB 5245 pp -- int.I2D: BioGrid
CDKN2A 1029 HNRNPU 3192 pp -- int.Intact: MI:0915(physical association)
HNRNPU 3192 ANAPC5 51433 pd < reg.ITFP.txt: no annot
HCFC1 3054 POU5F1 5460 pp -- int.I2D: BioGrid_Mouse, IntAct_Mouse
DDIT3 1649 NAP1L4 4676 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
PSMD2 5708 CNOT1 23019 pp -- int.I2D: YeastLow
DENR 8562 FBXO22 26263 pd < reg.ITFP.txt: no annot
CNOT1 23019 ANAPC5 51433 pd < reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
NOLC1 9221 MED19 219541 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct
NFRKB 4798 YY1 7528 pp -- int.I2D: BioGrid
MAPK14 1432 BTRC 8945 pd < reg.ITFP.txt: no annot
MAPK14 1432 BTRC 8945 pp -- int.I2D: BioGrid
GSPT1 2935 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
CDKN2A 1029 FTSJ1 24140 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
DENR 8562 ANAPC5 51433 pd < reg.ITFP.txt: no annot
NCBP1 4686 CBLL1 79872 pd < reg.ITFP.txt: no annot
CCT7 10574 FBXO22 26263 pd < reg.ITFP.txt: no annot
DENR 8562 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
DENR 8562 GTF3C3 9330 pd < reg.ITFP.txt: no annot
CBLL1 79872 MED28 80306 pd > reg.ITFP.txt: no annot
CDKN2A 1029 GSPT1 2935 pp -- int.I2D: BCI;
int.HPRD: in vitro, in vivo, yeast 2-hybrid
PHB 5245 PHB2 11331 pp -- int.I2D: BioGrid, BioGrid_Yeast, IntAct_Yeast
MED12 9968 MED19 219541 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid, IntAct
VARS 7407 FTSJ1 24140 pd > reg.ITFP.txt: no annot
CCNC 892 MED12 9968 pp -- int.I2D: BioGrid
DDIT3 1649 HNRNPU 3192 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
MED12 9968 MED28 80306 pp -- int.I2D: BioGrid
LUC7L3 51747 MED19 219541 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct
HNRNPU 3192 YAP1 10413 pp -- int.I2D: HPRD;
int.HPRD: in vitro, in vivo
HCFC1 3054 MED19 219541 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct
HNRNPU 3192 POU5F1 5460 pp -- int.I2D: BioGrid_Mouse, IntAct_Mouse
CCNC 892 MED13L 23389 pp -- int.I2D: IntAct_Fly, MINT_Fly
HNRNPU 3192 BTRC 8945 pp -- int.I2D: BCI, BioGrid, INNATEDB, HPRD;
int.HPRD: in vivo
PSMD2 5708 VARS 7407 pp -- int.I2D: BioGrid_Yeast
BTRC 8945 ZDHHC20 253832 pd > reg.ITFP.txt: no annot
MAPK14 1432 EIF2B2 8892 pp -- int.I2D: IntAct, SOURAV_MAPK_LOW
POU5F1 5460 SRSF3 6428 pp -- int.I2D: BioGrid
NAP1L4 4676 FOXJ3 22887 pd < reg.ITFP.txt: no annot
APC 324 FOXJ3 22887 pd <> reg.ITFP.txt: no annot
MAPK14 1432 ANAPC5 51433 pd < reg.ITFP.txt: no annot
DDIT3 1649 VARS 7407 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
MED28 80306 MED19 219541 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid, IntAct
MAPK14 1432 FUBP1 8880 pp -- int.I2D: BioGrid
AGPS 8540 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
MED13L 23389 MED28 80306 pp -- int.I2D: BioGrid
CASP2 835 DENR 8562 pd > reg.ITFP.txt: no annot
NFRKB 4798 POU5F1 5460 pp -- int.I2D: BioGrid_Mouse, IntAct_Mouse
ETF1 2107 EIF2S2 8894 pp -- int.I2D: BioGrid_Yeast, YeastLow
YAP1 10413 MED28 80306 pp -- int.I2D: MINT;
int.Mint: MI:0915(physical association)
BTRC 8945 CNOT1 23019 pd > reg.ITFP.txt: no annot
PSMD2 5708 CCT7 10574 pp -- int.I2D: BioGrid_Yeast
PHB2 11331 FTSJ1 24140 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
CCNC 892 EIF2B2 8892 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
DENR 8562 NOLC1 9221 pd < reg.ITFP.txt: no annot
EIF2B2 8892 EIF2S2 8894 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh
CDKN2A 1029 E4F1 1877 pp -- int.I2D: BioGrid;
int.HPRD: in vivo
SYNCRIP 10492 CPSF3 51692 pd > reg.ITFP.txt: no annot
SRSF3 6428 MED19 219541 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct
EIF2S2 8894 GTF3C3 9330 pd < reg.ITFP.txt: no annot
SYNCRIP 10492 SUV39H2 79723 pd > reg.ITFP.txt: no annot
MED13L 23389 ANAPC5 51433 pd < reg.ITFP.txt: no annot
CCNC 892 MED28 80306 pp -- int.I2D: BioGrid
PSMD2 5708 EIF2B2 8892 pp -- int.I2D: IntAct_Yeast
TIA1 7072 DENR 8562 pd > reg.ITFP.txt: no annot
DDIT3 1649 GSTP1 2950 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
CDKN2A 1029 YY1 7528 pd < reg.TRANSFAC.txt: no annot
CDKN2A 1029 YY1 7528 pp -- int.I2D: BioGrid, BIND, BCI
CCNC 892 MED19 219541 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid, IntAct
CASP2 835 SLC7A5P1 81893 pd > reg.ITFP.txt: no annot
MED13L 23389 MED19 219541 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid, IntAct
CASP2 835 CBLL1 79872 pd <> reg.ITFP.txt: no annot
NOLC1 9221 FTSJ1 24140 pd > reg.ITFP.txt: no annot
APC 324 BTRC 8945 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, IntAct, INNATEDB
GSPT1 2935 NOLC1 9221 pd < reg.ITFP.txt: no annot
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
CCNC 892 CNOT1 23019 pp -- int.I2D: BioGrid_Yeast
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
HNRNPU 3192 SYNCRIP 10492 pp -- int.Mint: MI:0915(physical association)
MAPK14 1432 SCN8A 6334 pp -- int.I2D: HPRD;
int.HPRD: in vivo
ICT1 3396 PHB2 11331 pp -- int.I2D: BioGrid
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
PHB 5245 SCN8A 6334 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
APC 324 SYNCRIP 10492 pp -- int.I2D: Jorgensen_EphR
FUBP1 8880 ANAPC5 51433 pd <> reg.ITFP.txt: no annot
ANAPC5 51433 MED19 219541 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
DENR 8562 BTRC 8945 pd < reg.ITFP.txt: no annot
BTRC 8945 YAP1 10413 pp -- int.I2D: BioGrid, MINT;
int.Mint: MI:0915(physical association)
PSMD2 5708 PHB2 11331 pp -- int.I2D: IntAct_Yeast

Related GO terms (646)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0005654nucleoplasm1.20e-091.97e-052.36419311095
GO:0010467gene expression3.43e-095.60e-052.7341527669
GO:0005515protein binding2.53e-084.13e-040.99041776127
GO:0016592mediator complex1.08e-071.77e-035.4065535
GO:0044822poly(A) RNA binding1.75e-062.86e-022.04615271078
GO:0006366transcription from RNA polymerase II promoter1.11e-051.82e-012.652914425
GO:0003723RNA binding2.31e-053.77e-012.741815355
GO:0003747translation release factor activity6.66e-051.00e+007.213224
GO:0070461SAGA-type complex1.11e-041.00e+006.891225
GO:0070934CRD-mediated mRNA stabilization1.11e-041.00e+006.891225
GO:0008380RNA splicing1.25e-041.00e+002.940614232
GO:0005739mitochondrion1.51e-041.00e+001.76712161046
GO:0070937CRD-mediated mRNA stability complex1.66e-041.00e+006.628226
GO:0001104RNA polymerase II transcription cofactor activity1.84e-041.00e+004.7543333
GO:0000398mRNA splicing, via spliceosome2.30e-041.00e+003.16959165
GO:0044212transcription regulatory region DNA binding2.71e-041.00e+003.11755171
GO:0031124mRNA 3'-end processing3.79e-041.00e+004.4063442
GO:0005829cytosol4.56e-041.00e+001.13819382562
GO:0006369termination of RNA polymerase II transcription4.65e-041.00e+004.3063445
GO:0010225response to UV-C4.93e-041.00e+005.8912210
GO:0006379mRNA cleavage4.93e-041.00e+005.8912210
GO:0033147negative regulation of intracellular estrogen receptor signaling pathway4.93e-041.00e+005.8912210
GO:0030529ribonucleoprotein complex5.85e-041.00e+003.38046114
GO:0003743translation initiation factor activity5.98e-041.00e+004.1833549
GO:0051010microtubule plus-end binding6.01e-041.00e+005.7542211
GO:0000209protein polyubiquitination6.25e-041.00e+003.35545116
GO:0008143poly(A) binding7.20e-041.00e+005.6282212
GO:0042789mRNA transcription from RNA polymerase II promoter8.49e-041.00e+005.5132213
GO:0043409negative regulation of MAPK cascade8.49e-041.00e+005.5132213
GO:0016071mRNA metabolic process9.09e-041.00e+002.73458223
GO:0031011Ino80 complex9.89e-041.00e+005.4062214
GO:0008013beta-catenin binding1.08e-031.00e+003.8913460
GO:0006479protein methylation1.14e-031.00e+005.3062215
GO:0006406mRNA export from nucleus1.19e-031.00e+003.8443562
GO:0003713transcription coactivator activity1.24e-031.00e+002.63457239
GO:0007026negative regulation of microtubule depolymerization1.30e-031.00e+005.2132216
GO:0051276chromosome organization1.30e-031.00e+005.2132216
GO:0016070RNA metabolic process1.43e-031.00e+002.58758247
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.69e-031.00e+003.6693470
GO:0005634nucleus1.78e-031.00e+000.73127554828
GO:0045736negative regulation of cyclin-dependent protein serine/threonine kinase activity1.84e-031.00e+004.9652219
GO:0006974cellular response to DNA damage stimulus1.96e-031.00e+002.90944158
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.98e-031.00e+003.5893474
GO:0014003oligodendrocyte development2.04e-031.00e+004.8912320
GO:0031648protein destabilization2.25e-031.00e+004.8212221
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process2.39e-031.00e+003.4943479
GO:0001205RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription2.47e-031.00e+004.7542222
GO:0045892negative regulation of transcription, DNA-templated2.93e-031.00e+002.07067424
GO:0003714transcription corepressor activity3.09e-031.00e+002.72945179
GO:0090090negative regulation of canonical Wnt signaling pathway3.25e-031.00e+003.3393488
GO:0070126mitochondrial translational termination3.37e-031.00e+008.213111
GO:0002128tRNA nucleoside ribose methylation3.37e-031.00e+008.213111
GO:2000016negative regulation of determination of dorsal identity3.37e-031.00e+008.213111
GO:0097057TRAF2-GSTP1 complex3.37e-031.00e+008.213111
GO:0042483negative regulation of odontogenesis3.37e-031.00e+008.213111
GO:0060795cell fate commitment involved in formation of primary germ layer3.37e-031.00e+008.213111
GO:0031592centrosomal corona3.37e-031.00e+008.213111
GO:0097165nuclear stress granule3.37e-031.00e+008.213111
GO:0016150translation release factor activity, codon nonspecific3.37e-031.00e+008.213111
GO:0051171regulation of nitrogen compound metabolic process3.37e-031.00e+008.213111
GO:0014835myoblast differentiation involved in skeletal muscle regeneration3.37e-031.00e+008.213111
GO:0008079translation termination factor activity3.37e-031.00e+008.213111
GO:0009794regulation of mitotic cell cycle, embryonic3.37e-031.00e+008.213111
GO:0070664negative regulation of leukocyte proliferation3.37e-031.00e+008.213111
GO:0035732nitric oxide storage3.37e-031.00e+008.213111
GO:0008609alkylglycerone-phosphate synthase activity3.37e-031.00e+008.213111
GO:0090308regulation of methylation-dependent chromatin silencing3.37e-031.00e+008.213111
GO:0090081regulation of heart induction by regulation of canonical Wnt signaling pathway3.37e-031.00e+008.213111
GO:0070026nitric oxide binding3.37e-031.00e+008.213111
GO:0035731dinitrosyl-iron complex binding3.37e-031.00e+008.213111
GO:0038066p38MAPK cascade3.37e-031.00e+008.213111
GO:0035730S-nitrosoglutathione binding3.37e-031.00e+008.213111
GO:0031047gene silencing by RNA3.44e-031.00e+004.5132226
GO:0030331estrogen receptor binding3.71e-031.00e+004.4582227
GO:0001649osteoblast differentiation4.03e-031.00e+003.2283395
GO:0007094mitotic spindle assembly checkpoint4.87e-031.00e+004.2592331
GO:0045944positive regulation of transcription from RNA polymerase II promoter5.51e-031.00e+001.550813811
GO:0006351transcription, DNA-templated5.71e-031.00e+001.16812171585
GO:0006446regulation of translational initiation6.53e-031.00e+004.0432236
GO:0042552myelination6.53e-031.00e+004.0432236
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay6.69e-031.00e+002.96533114
GO:0060242contact inhibition6.73e-031.00e+007.213112
GO:0045309protein phosphorylated amino acid binding6.73e-031.00e+007.213112
GO:0055105ubiquitin-protein transferase inhibitor activity6.73e-031.00e+007.213112
GO:0060965negative regulation of gene silencing by miRNA6.73e-031.00e+007.213112
GO:0030981cortical microtubule cytoskeleton6.73e-031.00e+007.213112
GO:0044324regulation of transcription involved in anterior/posterior axis specification6.73e-031.00e+007.213112
GO:0004832valine-tRNA ligase activity6.73e-031.00e+007.213112
GO:0006403RNA localization6.73e-031.00e+007.213112
GO:0009890negative regulation of biosynthetic process6.73e-031.00e+007.213112
GO:0044337canonical Wnt signaling pathway involved in positive regulation of apoptotic process6.73e-031.00e+007.213112
GO:0008175tRNA methyltransferase activity6.73e-031.00e+007.213112
GO:0019046release from viral latency6.73e-031.00e+007.213112
GO:0005846nuclear cap binding complex6.73e-031.00e+007.213112
GO:0002176male germ cell proliferation6.73e-031.00e+007.213112
GO:0006438valyl-tRNA aminoacylation6.73e-031.00e+007.213112
GO:0009786regulation of asymmetric cell division6.73e-031.00e+007.213112
GO:0019207kinase regulator activity6.73e-031.00e+007.213112
GO:0001554luteolysis6.73e-031.00e+007.213112
GO:1990440positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress6.73e-031.00e+007.213112
GO:0031111negative regulation of microtubule polymerization or depolymerization6.73e-031.00e+007.213112
GO:0034696response to prostaglandin F6.73e-031.00e+007.213112
GO:0051294establishment of spindle orientation6.73e-031.00e+007.213112
GO:0009798axis specification6.73e-031.00e+007.213112
GO:0035019somatic stem cell maintenance8.01e-031.00e+003.8912240
GO:0005881cytoplasmic microtubule8.41e-031.00e+003.8562241
GO:0017148negative regulation of translation8.41e-031.00e+003.8562341
GO:0007050cell cycle arrest8.80e-031.00e+002.82133126
GO:0071638negative regulation of monocyte chemotactic protein-1 production1.01e-021.00e+006.628113
GO:0016149translation release factor activity, codon specific1.01e-021.00e+006.628113
GO:0004045aminoacyl-tRNA hydrolase activity1.01e-021.00e+006.628113
GO:0036123histone H3-K9 dimethylation1.01e-021.00e+006.628113
GO:0035726common myeloid progenitor cell proliferation1.01e-021.00e+006.628113
GO:0035986senescence-associated heterochromatin focus assembly1.01e-021.00e+006.628113
GO:0090245axis elongation involved in somitogenesis1.01e-021.00e+006.628113
GO:2000111positive regulation of macrophage apoptotic process1.01e-021.00e+006.628113
GO:0005850eukaryotic translation initiation factor 2 complex1.01e-021.00e+006.628123
GO:0090400stress-induced premature senescence1.01e-021.00e+006.628113
GO:0035985senescence-associated heterochromatin focus1.01e-021.00e+006.628113
GO:0003130BMP signaling pathway involved in heart induction1.01e-021.00e+006.628113
GO:0043525positive regulation of neuron apoptotic process1.05e-021.00e+003.6902246
GO:0000278mitotic cell cycle1.08e-021.00e+001.898512398
GO:0006355regulation of transcription, DNA-templated1.09e-021.00e+001.2749131104
GO:0048511rhythmic process1.09e-021.00e+003.6582247
GO:0019827stem cell maintenance1.14e-021.00e+003.6282248
GO:0016020membrane1.21e-021.00e+001.02812271746
GO:0005778peroxisomal membrane1.23e-021.00e+003.5692250
GO:0003700sequence-specific DNA binding transcription factor activity1.24e-021.00e+001.474710748
GO:0014044Schwann cell development1.34e-021.00e+006.213114
GO:0042036negative regulation of cytokine biosynthetic process1.34e-021.00e+006.213114
GO:0097452GAIT complex1.34e-021.00e+006.213124
GO:0060913cardiac cell fate determination1.34e-021.00e+006.213114
GO:0007000nucleolus organization1.34e-021.00e+006.213114
GO:0051771negative regulation of nitric-oxide synthase biosynthetic process1.34e-021.00e+006.213114
GO:0046523S-methyl-5-thioribose-1-phosphate isomerase activity1.34e-021.00e+006.213114
GO:0033088negative regulation of immature T cell proliferation in thymus1.34e-021.00e+006.213114
GO:0019887protein kinase regulator activity1.34e-021.00e+006.213114
GO:0051716cellular response to stimulus1.34e-021.00e+006.213124
GO:2000774positive regulation of cellular senescence1.34e-021.00e+006.213114
GO:0008611ether lipid biosynthetic process1.34e-021.00e+006.213114
GO:0051151negative regulation of smooth muscle cell differentiation1.34e-021.00e+006.213114
GO:0006290pyrimidine dimer repair1.34e-021.00e+006.213114
GO:0043515kinetochore binding1.34e-021.00e+006.213114
GO:0002192IRES-dependent translational initiation1.34e-021.00e+006.213114
GO:0006357regulation of transcription from RNA polymerase II promoter1.37e-021.00e+002.11044275
GO:0003677DNA binding1.38e-021.00e+001.13510161351
GO:0000122negative regulation of transcription from RNA polymerase II promoter1.40e-021.00e+001.596610589
GO:0000082G1/S transition of mitotic cell cycle1.41e-021.00e+002.56934150
GO:0044336canonical Wnt signaling pathway involved in negative regulation of apoptotic process1.67e-021.00e+005.891115
GO:1902510regulation of apoptotic DNA fragmentation1.67e-021.00e+005.891115
GO:0048742regulation of skeletal muscle fiber development1.67e-021.00e+005.891115
GO:0045292mRNA cis splicing, via spliceosome1.67e-021.00e+005.891115
GO:0001714endodermal cell fate specification1.67e-021.00e+005.891115
GO:0003407neural retina development1.67e-021.00e+005.891115
GO:0097153cysteine-type endopeptidase activity involved in apoptotic process1.67e-021.00e+005.891115
GO:0005828kinetochore microtubule1.67e-021.00e+005.891115
GO:0043620regulation of DNA-templated transcription in response to stress1.67e-021.00e+005.891115
GO:0034393positive regulation of smooth muscle cell apoptotic process1.67e-021.00e+005.891115
GO:0010606positive regulation of cytoplasmic mRNA processing body assembly1.67e-021.00e+005.891115
GO:0031023microtubule organizing center organization1.67e-021.00e+005.891115
GO:0097371MDM2/MDM4 family protein binding1.67e-021.00e+005.891115
GO:0006398histone mRNA 3'-end processing1.67e-021.00e+005.891115
GO:0051525NFAT protein binding1.67e-021.00e+005.891115
GO:0031442positive regulation of mRNA 3'-end processing1.67e-021.00e+005.891115
GO:0033600negative regulation of mammary gland epithelial cell proliferation1.67e-021.00e+005.891115
GO:0006449regulation of translational termination1.67e-021.00e+005.891115
GO:1901741positive regulation of myoblast fusion1.67e-021.00e+005.891115
GO:0036124histone H3-K9 trimethylation1.67e-021.00e+005.891115
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity1.69e-021.00e+003.3302259
GO:0006396RNA processing1.74e-021.00e+003.3062460
GO:0000776kinetochore1.91e-021.00e+003.2362463
GO:0030858positive regulation of epithelial cell differentiation2.01e-021.00e+005.628116
GO:0042797tRNA transcription from RNA polymerase III promoter2.01e-021.00e+005.628126
GO:0010564regulation of cell cycle process2.01e-021.00e+005.628116
GO:0050847progesterone receptor signaling pathway2.01e-021.00e+005.628116
GO:0046974histone methyltransferase activity (H3-K9 specific)2.01e-021.00e+005.628116
GO:0032873negative regulation of stress-activated MAPK cascade2.01e-021.00e+005.628116
GO:0032691negative regulation of interleukin-1 beta production2.01e-021.00e+005.628116
GO:00427915S class rRNA transcription from RNA polymerase III type 1 promoter2.01e-021.00e+005.628126
GO:0006333chromatin assembly or disassembly2.01e-021.00e+005.628116
GO:0060762regulation of branching involved in mammary gland duct morphogenesis2.01e-021.00e+005.628116
GO:0008762UDP-N-acetylmuramate dehydrogenase activity2.01e-021.00e+005.628116
GO:0002181cytoplasmic translation2.01e-021.00e+005.628116
GO:0060744mammary gland branching involved in thelarche2.01e-021.00e+005.628116
GO:0048024regulation of mRNA splicing, via spliceosome2.01e-021.00e+005.628116
GO:2000323negative regulation of glucocorticoid receptor signaling pathway2.01e-021.00e+005.628116
GO:0005851eukaryotic translation initiation factor 2B complex2.01e-021.00e+005.628136
GO:0000127transcription factor TFIIIC complex2.01e-021.00e+005.628126
GO:0008432JUN kinase binding2.01e-021.00e+005.628116
GO:0071204histone pre-mRNA 3'end processing complex2.01e-021.00e+005.628116
GO:0035497cAMP response element binding2.01e-021.00e+005.628116
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest2.03e-021.00e+003.1912365
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.03e-021.00e+003.1912365
GO:0006469negative regulation of protein kinase activity2.03e-021.00e+003.1912265
GO:0032930positive regulation of superoxide anion generation2.34e-021.00e+005.406117
GO:0042753positive regulation of circadian rhythm2.34e-021.00e+005.406117
GO:0004521endoribonuclease activity2.34e-021.00e+005.406117
GO:0010458exit from mitosis2.34e-021.00e+005.406117
GO:0002674negative regulation of acute inflammatory response2.34e-021.00e+005.406117
GO:0007091metaphase/anaphase transition of mitotic cell cycle2.34e-021.00e+005.406117
GO:0060770negative regulation of epithelial cell proliferation involved in prostate gland development2.34e-021.00e+005.406117
GO:0046825regulation of protein export from nucleus2.34e-021.00e+005.406127
GO:0051988regulation of attachment of spindle microtubules to kinetochore2.34e-021.00e+005.406117
GO:0032790ribosome disassembly2.34e-021.00e+005.406117
GO:0002161aminoacyl-tRNA editing activity2.34e-021.00e+005.406117
GO:0006301postreplication repair2.34e-021.00e+005.406117
GO:0051444negative regulation of ubiquitin-protein transferase activity2.34e-021.00e+005.406117
GO:0006282regulation of DNA repair2.34e-021.00e+005.406117
GO:0035234ectopic germ cell programmed cell death2.34e-021.00e+005.406117
GO:0045893positive regulation of transcription, DNA-templated2.37e-021.00e+001.60756487
GO:0006367transcription initiation from RNA polymerase II promoter2.41e-021.00e+002.27435184
GO:0044267cellular protein metabolic process2.52e-021.00e+001.58457495
GO:0003682chromatin binding2.59e-021.00e+001.82947334
GO:0007265Ras protein signal transduction2.64e-021.00e+002.9842275
GO:0060070canonical Wnt signaling pathway2.64e-021.00e+002.9842275
GO:0032872regulation of stress-activated MAPK cascade2.66e-021.00e+005.213118
GO:0045670regulation of osteoclast differentiation2.66e-021.00e+005.213118
GO:0042754negative regulation of circadian rhythm2.66e-021.00e+005.213118
GO:0001955blood vessel maturation2.66e-021.00e+005.213118
GO:0043254regulation of protein complex assembly2.66e-021.00e+005.213118
GO:0000339RNA cap binding2.66e-021.00e+005.213118
GO:0070688MLL5-L complex2.66e-021.00e+005.213118
GO:0010831positive regulation of myotube differentiation2.66e-021.00e+005.213118
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process2.71e-021.00e+002.9652276
GO:0071013catalytic step 2 spliceosome2.91e-021.00e+002.9092379
GO:0010804negative regulation of tumor necrosis factor-mediated signaling pathway2.99e-021.00e+005.043119
GO:00084095'-3' exonuclease activity2.99e-021.00e+005.043119
GO:0048103somatic stem cell division2.99e-021.00e+005.043119
GO:0016591DNA-directed RNA polymerase II, holoenzyme2.99e-021.00e+005.043119
GO:0005847mRNA cleavage and polyadenylation specificity factor complex2.99e-021.00e+005.043119
GO:0043995histone acetyltransferase activity (H4-K5 specific)2.99e-021.00e+005.043119
GO:0033598mammary gland epithelial cell proliferation2.99e-021.00e+005.043119
GO:0000302response to reactive oxygen species2.99e-021.00e+005.043119
GO:0019509L-methionine biosynthetic process from methylthioadenosine2.99e-021.00e+005.043119
GO:0010389regulation of G2/M transition of mitotic cell cycle2.99e-021.00e+005.043119
GO:0006983ER overload response2.99e-021.00e+005.043119
GO:0000400four-way junction DNA binding2.99e-021.00e+005.043119
GO:0071354cellular response to interleukin-62.99e-021.00e+005.043119
GO:0043996histone acetyltransferase activity (H4-K8 specific)2.99e-021.00e+005.043119
GO:0046972histone acetyltransferase activity (H4-K16 specific)2.99e-021.00e+005.043119
GO:0048188Set1C/COMPASS complex2.99e-021.00e+005.043119
GO:0005832chaperonin-containing T-complex2.99e-021.00e+005.043119
GO:0032495response to muramyl dipeptide2.99e-021.00e+005.043129
GO:0071222cellular response to lipopolysaccharide3.05e-021.00e+002.8732281
GO:0009952anterior/posterior pattern specification3.26e-021.00e+002.8212284
GO:0002199zona pellucida receptor complex3.32e-021.00e+004.8911110
GO:0045667regulation of osteoblast differentiation3.32e-021.00e+004.8911110
GO:0001518voltage-gated sodium channel complex3.32e-021.00e+004.8911110
GO:0090399replicative senescence3.32e-021.00e+004.8911110
GO:0008610lipid biosynthetic process3.32e-021.00e+004.8911110
GO:0043194axon initial segment3.32e-021.00e+004.8911110
GO:0031274positive regulation of pseudopodium assembly3.32e-021.00e+004.8911110
GO:0006450regulation of translational fidelity3.32e-021.00e+004.8911110
GO:0071949FAD binding3.32e-021.00e+004.8911110
GO:1900153positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay3.32e-021.00e+004.8911110
GO:0000731DNA synthesis involved in DNA repair3.32e-021.00e+004.8911110
GO:0010944negative regulation of transcription by competitive promoter binding3.32e-021.00e+004.8911110
GO:0030877beta-catenin destruction complex3.32e-021.00e+004.8911110
GO:0006415translational termination3.48e-021.00e+002.7702287
GO:0016032viral process3.49e-021.00e+001.458516540
GO:0060071Wnt signaling pathway, planar cell polarity pathway3.65e-021.00e+004.7541111
GO:0048387negative regulation of retinoic acid receptor signaling pathway3.65e-021.00e+004.7541111
GO:0031116positive regulation of microtubule polymerization3.65e-021.00e+004.7541111
GO:0004535poly(A)-specific ribonuclease activity3.65e-021.00e+004.7541111
GO:2000036regulation of stem cell maintenance3.65e-021.00e+004.7541111
GO:0060391positive regulation of SMAD protein import into nucleus3.65e-021.00e+004.7541111
GO:0043122regulation of I-kappaB kinase/NF-kappaB signaling3.65e-021.00e+004.7541111
GO:0005845mRNA cap binding complex3.65e-021.00e+004.7541111
GO:0045663positive regulation of myoblast differentiation3.65e-021.00e+004.7541111
GO:0071850mitotic cell cycle arrest3.65e-021.00e+004.7541111
GO:0045662negative regulation of myoblast differentiation3.65e-021.00e+004.7541111
GO:0019395fatty acid oxidation3.65e-021.00e+004.7541111
GO:0004707MAP kinase activity3.65e-021.00e+004.7541111
GO:0060213positive regulation of nuclear-transcribed mRNA poly(A) tail shortening3.65e-021.00e+004.7541111
GO:0033235positive regulation of protein sumoylation3.65e-021.00e+004.7541111
GO:0035413positive regulation of catenin import into nucleus3.65e-021.00e+004.7541111
GO:0007178transmembrane receptor protein serine/threonine kinase signaling pathway3.65e-021.00e+004.7541111
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process3.65e-021.00e+004.7541111
GO:0042770signal transduction in response to DNA damage3.65e-021.00e+004.7541111
GO:0050821protein stabilization3.77e-021.00e+002.7052391
GO:0016363nuclear matrix3.85e-021.00e+002.6902592
GO:0034453microtubule anchoring3.97e-021.00e+004.6281112
GO:0061136regulation of proteasomal protein catabolic process3.97e-021.00e+004.6281112
GO:00709353'-UTR-mediated mRNA stabilization3.97e-021.00e+004.6281112
GO:0043517positive regulation of DNA damage response, signal transduction by p53 class mediator3.97e-021.00e+004.6281112
GO:0051146striated muscle cell differentiation3.97e-021.00e+004.6281112
GO:0045295gamma-catenin binding3.97e-021.00e+004.6281112
GO:0005838proteasome regulatory particle3.97e-021.00e+004.6281112
GO:0004861cyclin-dependent protein serine/threonine kinase inhibitor activity3.97e-021.00e+004.6281112
GO:0032886regulation of microtubule-based process3.97e-021.00e+004.6281112
GO:0008334histone mRNA metabolic process3.97e-021.00e+004.6281112
GO:0001953negative regulation of cell-matrix adhesion3.97e-021.00e+004.6281112
GO:0016874ligase activity3.97e-021.00e+001.99134224
GO:0043281regulation of cysteine-type endopeptidase activity involved in apoptotic process3.97e-021.00e+004.6281112
GO:0051082unfolded protein binding4.08e-021.00e+002.6432395
GO:0006364rRNA processing4.16e-021.00e+002.6282296
GO:0006915apoptotic process4.27e-021.00e+001.37858571
GO:0007140male meiosis4.29e-021.00e+004.5131113
GO:0043508negative regulation of JUN kinase activity4.29e-021.00e+004.5131113
GO:0030914STAGA complex4.29e-021.00e+004.5131113
GO:0042974retinoic acid receptor binding4.29e-021.00e+004.5131113
GO:0004708MAP kinase kinase activity4.29e-021.00e+004.5131113
GO:0007067mitotic nuclear division4.29e-021.00e+001.94634231
GO:0060766negative regulation of androgen receptor signaling pathway4.29e-021.00e+004.5131113
GO:0044295axonal growth cone4.29e-021.00e+004.5131113
GO:0030234enzyme regulator activity4.29e-021.00e+004.5131113
GO:0060444branching involved in mammary gland duct morphogenesis4.29e-021.00e+004.5131113
GO:0035198miRNA binding4.29e-021.00e+004.5131113
GO:0030018Z disc4.31e-021.00e+002.5982298
GO:0006412translation4.47e-021.00e+001.92235235
GO:0007417central nervous system development4.55e-021.00e+002.55522101
GO:0035371microtubule plus-end4.62e-021.00e+004.4061114
GO:0050905neuromuscular process4.62e-021.00e+004.4061114
GO:0030889negative regulation of B cell proliferation4.62e-021.00e+004.4061114
GO:0030518intracellular steroid hormone receptor signaling pathway4.62e-021.00e+004.4061114
GO:0071480cellular response to gamma radiation4.62e-021.00e+004.4061114
GO:0005685U1 snRNP4.62e-021.00e+004.4061114
GO:0007020microtubule nucleation4.62e-021.00e+004.4061114
GO:0045807positive regulation of endocytosis4.62e-021.00e+004.4061114
GO:0042809vitamin D receptor binding4.94e-021.00e+004.3061115
GO:0043981histone H4-K5 acetylation4.94e-021.00e+004.3061115
GO:0017091AU-rich element binding4.94e-021.00e+004.3061215
GO:0005671Ada2/Gcn5/Ada3 transcription activator complex4.94e-021.00e+004.3061115
GO:0001824blastocyst development4.94e-021.00e+004.3061115
GO:0043982histone H4-K8 acetylation4.94e-021.00e+004.3061115
GO:0030014CCR4-NOT complex4.94e-021.00e+004.3061115
GO:0060749mammary gland alveolus development4.94e-021.00e+004.3061115
GO:0006376mRNA splice site selection4.94e-021.00e+004.3061115
GO:0042307positive regulation of protein import into nucleus4.94e-021.00e+004.3061215
GO:0005762mitochondrial large ribosomal subunit4.94e-021.00e+004.3061115
GO:0008134transcription factor binding5.00e-021.00e+001.85636246
GO:0033268node of Ranvier5.26e-021.00e+004.2131116
GO:0001190RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription5.26e-021.00e+004.2131116
GO:0042176regulation of protein catabolic process5.26e-021.00e+004.2131116
GO:0046716muscle cell cellular homeostasis5.26e-021.00e+004.2131116
GO:0005248voltage-gated sodium channel activity5.26e-021.00e+004.2131116
GO:0005730nucleolus5.28e-021.00e+000.81710281684
GO:0004842ubiquitin-protein transferase activity5.51e-021.00e+001.79835256
GO:0030308negative regulation of cell growth5.56e-021.00e+002.39322113
GO:0043274phospholipase binding5.58e-021.00e+004.1261117
GO:0016409palmitoyltransferase activity5.58e-021.00e+004.1261117
GO:0043536positive regulation of blood vessel endothelial cell migration5.58e-021.00e+004.1261117
GO:0022624proteasome accessory complex5.58e-021.00e+004.1261117
GO:0048593camera-type eye morphogenesis5.58e-021.00e+004.1261117
GO:0001829trophectodermal cell differentiation5.58e-021.00e+004.1261217
GO:0070372regulation of ERK1 and ERK2 cascade5.58e-021.00e+004.1261117
GO:0001731formation of translation preinitiation complex5.58e-021.00e+004.1261117
GO:0031122cytoplasmic microtubule organization5.90e-021.00e+004.0431118
GO:0019228neuronal action potential5.90e-021.00e+004.0431118
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process6.22e-021.00e+003.9651119
GO:0071158positive regulation of cell cycle arrest6.22e-021.00e+003.9651119
GO:0043984histone H4-K16 acetylation6.22e-021.00e+003.9651119
GO:0000166nucleotide binding6.38e-021.00e+001.71136272
GO:0006325chromatin organization6.46e-021.00e+002.27123123
GO:0090398cellular senescence6.53e-021.00e+003.8911120
GO:0051090regulation of sequence-specific DNA binding transcription factor activity6.53e-021.00e+003.8911120
GO:0018345protein palmitoylation6.53e-021.00e+003.8911120
GO:0001578microtubule bundle formation6.53e-021.00e+003.8911120
GO:0001502cartilage condensation6.53e-021.00e+003.8911120
GO:0035924cellular response to vascular endothelial growth factor stimulus6.53e-021.00e+003.8911120
GO:0097194execution phase of apoptosis6.53e-021.00e+003.8911120
GO:0005680anaphase-promoting complex6.53e-021.00e+003.8911120
GO:0001227RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription6.53e-021.00e+003.8911120
GO:0006260DNA replication6.64e-021.00e+002.24724125
GO:0006511ubiquitin-dependent protein catabolic process6.83e-021.00e+002.22423127
GO:0048010vascular endothelial growth factor receptor signaling pathway6.85e-021.00e+003.8211121
GO:0045648positive regulation of erythrocyte differentiation6.85e-021.00e+003.8211121
GO:0045862positive regulation of proteolysis6.85e-021.00e+003.8211221
GO:0000123histone acetyltransferase complex6.85e-021.00e+003.8211221
GO:0004364glutathione transferase activity6.85e-021.00e+003.8211121
GO:0042326negative regulation of phosphorylation6.85e-021.00e+003.8211121
GO:0016575histone deacetylation6.85e-021.00e+003.8211121
GO:0008637apoptotic mitochondrial changes6.85e-021.00e+003.8211121
GO:0032757positive regulation of interleukin-8 production6.85e-021.00e+003.8211121
GO:0009954proximal/distal pattern formation6.85e-021.00e+003.8211121
GO:0000281mitotic cytokinesis6.85e-021.00e+003.8211121
GO:0030335positive regulation of cell migration7.11e-021.00e+002.19122130
GO:0030316osteoclast differentiation7.16e-021.00e+003.7541122
GO:0005720nuclear heterochromatin7.16e-021.00e+003.7541122
GO:0006378mRNA polyadenylation7.16e-021.00e+003.7541222
GO:0036464cytoplasmic ribonucleoprotein granule7.16e-021.00e+003.7541122
GO:0006413translational initiation7.21e-021.00e+002.18024131
GO:0034660ncRNA metabolic process7.47e-021.00e+003.6901123
GO:0045787positive regulation of cell cycle7.47e-021.00e+003.6901123
GO:0045879negative regulation of smoothened signaling pathway7.47e-021.00e+003.6901123
GO:0071346cellular response to interferon-gamma7.47e-021.00e+003.6901223
GO:1901687glutathione derivative biosynthetic process7.47e-021.00e+003.6901123
GO:0019706protein-cysteine S-palmitoyltransferase activity7.47e-021.00e+003.6901123
GO:0008135translation factor activity, nucleic acid binding7.79e-021.00e+003.6281224
GO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress7.79e-021.00e+003.6281124
GO:0007163establishment or maintenance of cell polarity7.79e-021.00e+003.6281124
GO:0000086G2/M transition of mitotic cell cycle7.79e-021.00e+002.11523137
GO:0048147negative regulation of fibroblast proliferation7.79e-021.00e+003.6281124
GO:2000379positive regulation of reactive oxygen species metabolic process7.79e-021.00e+003.6281124
GO:0016567protein ubiquitination7.97e-021.00e+001.57435299
GO:0000289nuclear-transcribed mRNA poly(A) tail shortening8.10e-021.00e+003.5691125
GO:0031519PcG protein complex8.10e-021.00e+003.5691125
GO:0051059NF-kappaB binding8.10e-021.00e+003.5691225
GO:0071479cellular response to ionizing radiation8.10e-021.00e+003.5691125
GO:0086010membrane depolarization during action potential8.10e-021.00e+003.5691125
GO:0030864cortical actin cytoskeleton8.10e-021.00e+003.5691125
GO:0045296cadherin binding8.10e-021.00e+003.5691125
GO:0016055Wnt signaling pathway8.18e-021.00e+002.07423141
GO:0070979protein K11-linked ubiquitination8.41e-021.00e+003.5131126
GO:0090503RNA phosphodiester bond hydrolysis, exonucleolytic8.41e-021.00e+003.5131126
GO:0046966thyroid hormone receptor binding8.41e-021.00e+003.5131126
GO:0035329hippo signaling8.41e-021.00e+003.5131126
GO:0051209release of sequestered calcium ion into cytosol8.41e-021.00e+003.5131226
GO:0051149positive regulation of muscle cell differentiation8.72e-021.00e+003.4581127
GO:0032720negative regulation of tumor necrosis factor production8.72e-021.00e+003.4581227
GO:0000387spliceosomal snRNP assembly8.72e-021.00e+003.4581127
GO:0071339MLL1 complex8.72e-021.00e+003.4581127
GO:0007422peripheral nervous system development8.72e-021.00e+003.4581127
GO:0006913nucleocytoplasmic transport8.72e-021.00e+003.4581127
GO:0007339binding of sperm to zona pellucida8.72e-021.00e+003.4581127
GO:0010628positive regulation of gene expression8.99e-021.00e+001.99422149
GO:0000077DNA damage checkpoint9.03e-021.00e+003.4061128
GO:0000976transcription regulatory region sequence-specific DNA binding9.03e-021.00e+003.4061128
GO:0043022ribosome binding9.03e-021.00e+003.4061228
GO:2001235positive regulation of apoptotic signaling pathway9.03e-021.00e+003.4061128
GO:0008017microtubule binding9.09e-021.00e+001.98424150
GO:0042981regulation of apoptotic process9.19e-021.00e+001.97523151
GO:0019901protein kinase binding9.31e-021.00e+001.47634320
GO:0019005SCF ubiquitin ligase complex9.33e-021.00e+003.3551129
GO:0007628adult walking behavior9.33e-021.00e+003.3551129
GO:0071897DNA biosynthetic process9.33e-021.00e+003.3551129
GO:0005913cell-cell adherens junction9.33e-021.00e+003.3551129
GO:0016485protein processing9.33e-021.00e+003.3551129
GO:0006749glutathione metabolic process9.33e-021.00e+003.3551129
GO:0003887DNA-directed DNA polymerase activity9.33e-021.00e+003.3551129
GO:0031663lipopolysaccharide-mediated signaling pathway9.33e-021.00e+003.3551129
GO:0043124negative regulation of I-kappaB kinase/NF-kappaB signaling9.64e-021.00e+003.3061130
GO:00063707-methylguanosine mRNA capping9.64e-021.00e+003.3061230
GO:0031647regulation of protein stability9.64e-021.00e+003.3061230
GO:0010494cytoplasmic stress granule9.64e-021.00e+003.3061230
GO:0005525GTP binding9.85e-021.00e+001.44035328
GO:0070373negative regulation of ERK1 and ERK2 cascade9.94e-021.00e+003.2591131
GO:0005782peroxisomal matrix9.94e-021.00e+003.2591131
GO:0016604nuclear body9.94e-021.00e+003.2591131
GO:0070534protein K63-linked ubiquitination9.94e-021.00e+003.2591131
GO:0005737cytoplasm1.01e-011.00e+000.42618433976
GO:0042594response to starvation1.02e-011.00e+003.2131332
GO:0034644cellular response to UV1.02e-011.00e+003.2131132
GO:0002062chondrocyte differentiation1.02e-011.00e+003.2131232
GO:1903507negative regulation of nucleic acid-templated transcription1.02e-011.00e+003.2131132
GO:0009953dorsal/ventral pattern formation1.02e-011.00e+003.2131132
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic1.02e-011.00e+003.2131132
GO:0007162negative regulation of cell adhesion1.06e-011.00e+003.1691133
GO:0070830tight junction assembly1.06e-011.00e+003.1691133
GO:0033077T cell differentiation in thymus1.06e-011.00e+003.1691133
GO:0043407negative regulation of MAP kinase activity1.09e-011.00e+003.1261134
GO:0042692muscle cell differentiation1.09e-011.00e+003.1261134
GO:0005876spindle microtubule1.09e-011.00e+003.1261134
GO:2001237negative regulation of extrinsic apoptotic signaling pathway1.12e-011.00e+003.0841135
GO:0097192extrinsic apoptotic signaling pathway in absence of ligand1.12e-011.00e+003.0841135
GO:0001942hair follicle development1.12e-011.00e+003.0841135
GO:0048538thymus development1.15e-011.00e+003.0431136
GO:0030178negative regulation of Wnt signaling pathway1.15e-011.00e+003.0431136
GO:0009267cellular response to starvation1.15e-011.00e+003.0431136
GO:0051084'de novo' posttranslational protein folding1.18e-011.00e+003.0041137
GO:0016607nuclear speck1.18e-011.00e+001.76226175
GO:0001541ovarian follicle development1.18e-011.00e+003.0041137
GO:0042752regulation of circadian rhythm1.18e-011.00e+003.0041337
GO:0007049cell cycle1.20e-011.00e+001.74524177
GO:0005667transcription factor complex1.21e-011.00e+001.73723178
GO:0051781positive regulation of cell division1.23e-011.00e+002.9281139
GO:0006383transcription from RNA polymerase III promoter1.23e-011.00e+002.9281339
GO:0071407cellular response to organic cyclic compound1.23e-011.00e+002.9281339
GO:0019904protein domain specific binding1.24e-011.00e+001.71322181
GO:0043565sequence-specific DNA binding1.25e-011.00e+001.28633365
GO:0009408response to heat1.26e-011.00e+002.8911240
GO:0008285negative regulation of cell proliferation1.26e-011.00e+001.27834367
GO:0030521androgen receptor signaling pathway1.29e-011.00e+002.8561141
GO:0045785positive regulation of cell adhesion1.29e-011.00e+002.8561141
GO:0007519skeletal muscle tissue development1.29e-011.00e+002.8561241
GO:0006418tRNA aminoacylation for protein translation1.32e-011.00e+002.8211342
GO:0030374ligand-dependent nuclear receptor transcription coactivator activity1.35e-011.00e+002.7871143
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process1.38e-011.00e+002.7541144
GO:0003712transcription cofactor activity1.38e-011.00e+002.7541144
GO:0050434positive regulation of viral transcription1.38e-011.00e+002.7541244
GO:0015030Cajal body1.41e-011.00e+002.7211145
GO:0016328lateral plasma membrane1.44e-011.00e+002.6901146
GO:0044297cell body1.44e-011.00e+002.6901146
GO:0043434response to peptide hormone1.44e-011.00e+002.6901246
GO:0000079regulation of cyclin-dependent protein serine/threonine kinase activity1.47e-011.00e+002.6581147
GO:0006921cellular component disassembly involved in execution phase of apoptosis1.47e-011.00e+002.6581147
GO:0008630intrinsic apoptotic signaling pathway in response to DNA damage1.53e-011.00e+002.5981149
GO:0006521regulation of cellular amino acid metabolic process1.56e-011.00e+002.5691250
GO:0040008regulation of growth1.58e-011.00e+002.5411151
GO:0003684damaged DNA binding1.58e-011.00e+002.5411151
GO:0006986response to unfolded protein1.58e-011.00e+002.5411251
GO:0000902cell morphogenesis1.58e-011.00e+002.5411151
GO:0045732positive regulation of protein catabolic process1.58e-011.00e+002.5411151
GO:0045454cell redox homeostasis1.61e-011.00e+002.5131152
GO:0000775chromosome, centromeric region1.61e-011.00e+002.5131352
GO:0004197cysteine-type endopeptidase activity1.61e-011.00e+002.5131152
GO:0034976response to endoplasmic reticulum stress1.61e-011.00e+002.5131152
GO:0009611response to wounding1.64e-011.00e+002.4851153
GO:0060041retina development in camera-type eye1.64e-011.00e+002.4851153
GO:0000288nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay1.64e-011.00e+002.4851253
GO:0051403stress-activated MAPK cascade1.67e-011.00e+002.4581254
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding1.67e-011.00e+002.4581154
GO:0005524ATP binding1.68e-011.00e+000.6177131354
GO:0002039p53 binding1.70e-011.00e+002.4321355
GO:0000226microtubule cytoskeleton organization1.70e-011.00e+002.4321255
GO:0006814sodium ion transport1.70e-011.00e+002.4321155
GO:0000932cytoplasmic mRNA processing body1.73e-011.00e+002.4061256
GO:0000724double-strand break repair via homologous recombination1.75e-011.00e+002.3801157
GO:0005622intracellular1.77e-011.00e+001.39322226
GO:0000502proteasome complex1.78e-011.00e+002.3551258
GO:0035725sodium ion transmembrane transport1.78e-011.00e+002.3551158
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription1.89e-011.00e+002.2591162
GO:0006987activation of signaling protein activity involved in unfolded protein response1.89e-011.00e+002.2591262
GO:0000151ubiquitin ligase complex1.92e-011.00e+002.2361263
GO:0006417regulation of translation1.92e-011.00e+002.2361163
GO:0019903protein phosphatase binding1.92e-011.00e+002.2361163
GO:0032088negative regulation of NF-kappaB transcription factor activity1.95e-011.00e+002.2131264
GO:0009749response to glucose1.95e-011.00e+002.2131264
GO:0034146toll-like receptor 5 signaling pathway1.97e-011.00e+002.1911265
GO:0034166toll-like receptor 10 signaling pathway1.97e-011.00e+002.1911265
GO:0071260cellular response to mechanical stimulus2.00e-011.00e+002.1691166
GO:0009636response to toxic substance2.00e-011.00e+002.1691166
GO:0007409axonogenesis2.00e-011.00e+002.1691166
GO:0006368transcription elongation from RNA polymerase II promoter2.03e-011.00e+002.1471367
GO:0006310DNA recombination2.03e-011.00e+002.1471267
GO:0000777condensed chromosome kinetochore2.05e-011.00e+002.1261168
GO:0006338chromatin remodeling2.05e-011.00e+002.1261168
GO:0003697single-stranded DNA binding2.08e-011.00e+002.1051269
GO:0018105peptidyl-serine phosphorylation2.08e-011.00e+002.1051169
GO:0043025neuronal cell body2.11e-011.00e+001.22423254
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway2.14e-011.00e+002.0631271
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway2.14e-011.00e+002.0631271
GO:0034162toll-like receptor 9 signaling pathway2.16e-011.00e+002.0431272
GO:0032587ruffle membrane2.16e-011.00e+002.0431172
GO:0010468regulation of gene expression2.16e-011.00e+002.0431172
GO:0034134toll-like receptor 2 signaling pathway2.19e-011.00e+002.0231273
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent2.19e-011.00e+002.0231273
GO:0003729mRNA binding2.19e-011.00e+002.0231373
GO:0000785chromatin2.19e-011.00e+002.0231273
GO:0042826histone deacetylase binding2.21e-011.00e+002.0041274
GO:0005085guanyl-nucleotide exchange factor activity2.21e-011.00e+002.0041274
GO:0002020protease binding2.21e-011.00e+002.0041174
GO:0006281DNA repair2.23e-011.00e+001.16924264
GO:0001843neural tube closure2.24e-011.00e+001.9841175
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding2.24e-011.00e+001.9841175
GO:0035666TRIF-dependent toll-like receptor signaling pathway2.27e-011.00e+001.9651276
GO:0042802identical protein binding2.29e-011.00e+000.85836491
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I2.29e-011.00e+001.9461277
GO:0008584male gonad development2.29e-011.00e+001.9461177
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process2.29e-011.00e+001.9461277
GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activity2.29e-011.00e+001.9461277
GO:0002756MyD88-independent toll-like receptor signaling pathway2.32e-011.00e+001.9281278
GO:0001822kidney development2.35e-011.00e+001.9091279
GO:0006334nucleosome assembly2.35e-011.00e+001.9091379
GO:0048011neurotrophin TRK receptor signaling pathway2.35e-011.00e+001.12022273
GO:0043065positive regulation of apoptotic process2.36e-011.00e+001.11523274
GO:0002755MyD88-dependent toll-like receptor signaling pathway2.37e-011.00e+001.8911380
GO:0034138toll-like receptor 3 signaling pathway2.37e-011.00e+001.8911280
GO:0051301cell division2.40e-011.00e+001.8731281
GO:0030968endoplasmic reticulum unfolded protein response2.40e-011.00e+001.8731281
GO:0007517muscle organ development2.45e-011.00e+001.8381183
GO:0019899enzyme binding2.53e-011.00e+001.04323288
GO:0009653anatomical structure morphogenesis2.55e-011.00e+001.7701187
GO:0006464cellular protein modification process2.60e-011.00e+001.7371189
GO:0005777peroxisome2.63e-011.00e+001.7211190
GO:0000187activation of MAPK activity2.63e-011.00e+001.7211290
GO:0000922spindle pole2.65e-011.00e+001.7051191
GO:0016337single organismal cell-cell adhesion2.68e-011.00e+001.6901192
GO:0006928cellular component movement2.68e-011.00e+001.6901192
GO:0005743mitochondrial inner membrane2.68e-011.00e+000.98423300
GO:0005923tight junction2.68e-011.00e+001.6901192
GO:0043234protein complex2.68e-011.00e+000.98424300
GO:0002474antigen processing and presentation of peptide antigen via MHC class I2.73e-011.00e+001.6581294
GO:0005770late endosome2.73e-011.00e+001.6581194
GO:0034142toll-like receptor 4 signaling pathway2.77e-011.00e+001.6281296
GO:0071456cellular response to hypoxia2.82e-011.00e+001.5981298
GO:0006470protein dephosphorylation2.85e-011.00e+001.5841199
GO:0008270zinc ion binding2.90e-011.00e+000.4765111067
GO:0051726regulation of cell cycle2.92e-011.00e+001.54114102
GO:0030154cell differentiation3.00e-011.00e+000.86922325
GO:0007411axon guidance3.02e-011.00e+000.86022327
GO:0016023cytoplasmic membrane-bounded vesicle3.04e-011.00e+001.47211107
GO:0006935chemotaxis3.06e-011.00e+001.45811108
GO:0008283cell proliferation3.07e-011.00e+000.84223331
GO:0002224toll-like receptor signaling pathway3.09e-011.00e+001.44512109
GO:0005938cell cortex3.09e-011.00e+001.44511109
GO:0006461protein complex assembly3.13e-011.00e+001.41912111
GO:0007605sensory perception of sound3.13e-011.00e+001.41911111
GO:0005813centrosome3.17e-011.00e+000.80824339
GO:0034765regulation of ion transmembrane transport3.18e-011.00e+001.39311113
GO:0005819spindle3.20e-011.00e+001.38012114
GO:0097190apoptotic signaling pathway3.25e-011.00e+001.35511116
GO:0006006glucose metabolic process3.32e-011.00e+001.31811119
GO:0007568aging3.41e-011.00e+001.27112123
GO:0007219Notch signaling pathway3.45e-011.00e+001.24712125
GO:0006805xenobiotic metabolic process3.54e-011.00e+001.20211129
GO:0030027lamellipodium3.56e-011.00e+001.19111130
GO:0007179transforming growth factor beta receptor signaling pathway3.56e-011.00e+001.19111130
GO:0016477cell migration3.59e-011.00e+001.18012131
GO:0046983protein dimerization activity3.59e-011.00e+001.18011131
GO:0031982vesicle3.65e-011.00e+001.14712134
GO:0044255cellular lipid metabolic process3.78e-011.00e+001.08411140
GO:0007507heart development3.80e-011.00e+001.07412141
GO:0006457protein folding3.97e-011.00e+000.99411149
GO:0007166cell surface receptor signaling pathway3.97e-011.00e+000.99411149
GO:0008022protein C-terminus binding4.21e-011.00e+000.88211161
GO:0043066negative regulation of apoptotic process4.31e-011.00e+000.45525433
GO:0007420brain development4.42e-011.00e+000.78711172
GO:0034641cellular nitrogen compound metabolic process4.52e-011.00e+000.74513177
GO:0031625ubiquitin protein ligase binding4.57e-011.00e+000.72112180
GO:0043547positive regulation of GTPase activity4.75e-011.00e+000.64312190
GO:0004872receptor activity4.91e-011.00e+000.57611199
GO:0001525angiogenesis4.93e-011.00e+000.56911200
GO:0003924GTPase activity4.98e-011.00e+000.54812203
GO:0030168platelet activation5.02e-011.00e+000.53411205
GO:0001701in utero embryonic development5.10e-011.00e+000.49912210
GO:0006184GTP catabolic process5.27e-011.00e+000.43212220
GO:0030425dendrite5.58e-011.00e+000.30611240
GO:0007399nervous system development5.65e-011.00e+000.27613245
GO:0005874microtubule5.84e-011.00e+000.20213258
GO:0003779actin binding6.08e-011.00e+000.11011275
GO:0007283spermatogenesis6.09e-011.00e+000.10511276
GO:0006954inflammatory response6.26e-011.00e+000.03811289
GO:0007165signal transduction6.28e-011.00e+00-0.09438950
GO:0004674protein serine/threonine kinase activity6.55e-011.00e+00-0.07212312
GO:0035556intracellular signal transduction6.61e-011.00e+00-0.09512317
GO:0005575cellular_component6.66e-011.00e+00-0.11811322
GO:0043231intracellular membrane-bounded organelle6.78e-011.00e+00-0.16211332
GO:0005925focal adhesion7.17e-011.00e+00-0.31812370
GO:0007155cell adhesion7.31e-011.00e+00-0.37212384
GO:0046872metal ion binding7.40e-011.00e+00-0.304461465
GO:0046982protein heterodimerization activity7.44e-011.00e+00-0.42713399
GO:0006508proteolysis7.54e-011.00e+00-0.46612410
GO:0009986cell surface7.64e-011.00e+00-0.50814422
GO:0070062extracellular vesicular exosome7.64e-011.00e+00-0.2767152516
GO:0007596blood coagulation7.96e-011.00e+00-0.64511464
GO:0055114oxidation-reduction process8.08e-011.00e+00-0.69712481
GO:0044281small molecule metabolic process8.23e-011.00e+00-0.5413121295
GO:0003674molecular_function8.34e-011.00e+00-0.82011524
GO:0005615extracellular space8.63e-011.00e+00-0.767241010
GO:0005783endoplasmic reticulum8.77e-011.00e+00-1.04012610
GO:0045087innate immune response8.80e-011.00e+00-1.05414616
GO:0005794Golgi apparatus8.93e-011.00e+00-1.13111650
GO:0005886plasma membrane9.33e-011.00e+00-0.6716142834
GO:0005887integral component of plasma membrane9.65e-011.00e+00-1.69511961
GO:0016021integral component of membrane9.99e-011.00e+00-2.065272483