Related GO terms (1114)

Accession number Name Occurrences in all snw genes Occurrences in all int/reg genes
GO:0070461SAGA-type complex25
GO:0009897external side of plasma membrane1183
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process144
GO:0042797tRNA transcription from RNA polymerase III promoter26
GO:0010564regulation of cell cycle process16
GO:0005769early endosome1158
GO:0014044Schwann cell development14
GO:0032088negative regulation of NF-kappaB transcription factor activity264
GO:0030332cyclin binding118
GO:0032839dendrite cytoplasm116
GO:0050847progesterone receptor signaling pathway16
GO:0001525angiogenesis1200
GO:0008360regulation of cell shape1106
GO:0002314germinal center B cell differentiation12
GO:0002367cytokine production involved in immune response11
GO:0003677DNA binding161351
GO:0030168platelet activation1205
GO:0003725double-stranded RNA binding154
GO:0043508negative regulation of JUN kinase activity113
GO:0044336canonical Wnt signaling pathway involved in negative regulation of apoptotic process15
GO:0051353positive regulation of oxidoreductase activity17
GO:0070126mitochondrial translational termination11
GO:0010506regulation of autophagy123
GO:0043928exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay129
GO:0004872receptor activity1199
GO:0051092positive regulation of NF-kappaB transcription factor activity1125
GO:0071638negative regulation of monocyte chemotactic protein-1 production13
GO:0031047gene silencing by RNA226
GO:0060071Wnt signaling pathway, planar cell polarity pathway111
GO:0051149positive regulation of muscle cell differentiation127
GO:0045670regulation of osteoclast differentiation18
GO:0017025TBP-class protein binding118
GO:0048010vascular endothelial growth factor receptor signaling pathway121
GO:0090305nucleic acid phosphodiester bond hydrolysis154
GO:0000045autophagic vacuole assembly126
GO:0042036negative regulation of cytokine biosynthetic process14
GO:0030316osteoclast differentiation122
GO:0060242contact inhibition12
GO:0006821chloride transport137
GO:0001756somitogenesis138
GO:0001102RNA polymerase II activating transcription factor binding137
GO:0045892negative regulation of transcription, DNA-templated7424
GO:0009653anatomical structure morphogenesis187
GO:0006139nucleobase-containing compound metabolic process132
GO:0008017microtubule binding4150
GO:0042100B cell proliferation125
GO:0030902hindbrain development116
GO:0051084'de novo' posttranslational protein folding137
GO:0042789mRNA transcription from RNA polymerase II promoter213
GO:1902510regulation of apoptotic DNA fragmentation15
GO:0002376immune system process137
GO:0008283cell proliferation3331
GO:0031463Cul3-RING ubiquitin ligase complex123
GO:0006974cellular response to DNA damage stimulus4158
GO:0031122cytoplasmic microtubule organization118
GO:0043484regulation of RNA splicing123
GO:0008630intrinsic apoptotic signaling pathway in response to DNA damage149
GO:0005672transcription factor TFIIA complex15
GO:0048387negative regulation of retinoic acid receptor signaling pathway111
GO:0035419activation of MAPK activity involved in innate immune response12
GO:0043969histone H2B acetylation11
GO:0045747positive regulation of Notch signaling pathway123
GO:0034134toll-like receptor 2 signaling pathway273
GO:0043627response to estrogen157
GO:0004818glutamate-tRNA ligase activity12
GO:0008180COP9 signalosome634
GO:0006154adenosine catabolic process12
GO:0030277maintenance of gastrointestinal epithelium111
GO:0007165signal transduction8950
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay3114
GO:0032873negative regulation of stress-activated MAPK cascade16
GO:0046777protein autophosphorylation3158
GO:0050733RS domain binding16
GO:0060913cardiac cell fate determination14
GO:0000151ubiquitin ligase complex263
GO:0045944positive regulation of transcription from RNA polymerase II promoter13811
GO:0001518voltage-gated sodium channel complex110
GO:0051726regulation of cell cycle4102
GO:0031011Ino80 complex214
GO:0055114oxidation-reduction process2481
GO:0032703negative regulation of interleukin-2 production110
GO:0045309protein phosphorylated amino acid binding12
GO:0034162toll-like receptor 9 signaling pathway272
GO:0003712transcription cofactor activity144
GO:0016591DNA-directed RNA polymerase II, holoenzyme19
GO:0007623circadian rhythm254
GO:0045111intermediate filament cytoskeleton149
GO:0010388cullin deneddylation59
GO:0006954inflammatory response1289
GO:0043966histone H3 acetylation145
GO:0006952defense response153
GO:0008134transcription factor binding6246
GO:0005783endoplasmic reticulum2610
GO:0005847mRNA cleavage and polyadenylation specificity factor complex19
GO:0031982vesicle2134
GO:0032967positive regulation of collagen biosynthetic process121
GO:0090043regulation of tubulin deacetylation12
GO:0003697single-stranded DNA binding269
GO:0043065positive regulation of apoptotic process3274
GO:0043517positive regulation of DNA damage response, signal transduction by p53 class mediator112
GO:0045087innate immune response4616
GO:0009612response to mechanical stimulus154
GO:0030154cell differentiation2325
GO:0000398mRNA splicing, via spliceosome9165
GO:0043066negative regulation of apoptotic process5433
GO:0016032viral process16540
GO:0001666response to hypoxia3150
GO:0008022protein C-terminus binding1161
GO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress124
GO:0002227innate immune response in mucosa120
GO:0006367transcription initiation from RNA polymerase II promoter5184
GO:0000976transcription regulatory region sequence-specific DNA binding128
GO:0035556intracellular signal transduction2317
GO:0002474antigen processing and presentation of peptide antigen via MHC class I294
GO:0000289nuclear-transcribed mRNA poly(A) tail shortening125
GO:0006470protein dephosphorylation199
GO:0001934positive regulation of protein phosphorylation1108
GO:0005871kinesin complex144
GO:0004298threonine-type endopeptidase activity120
GO:0060169negative regulation of adenosine receptor signaling pathway11
GO:0002039p53 binding355
GO:0034765regulation of ion transmembrane transport1113
GO:0006366transcription from RNA polymerase II promoter14425
GO:0042594response to starvation332
GO:0019904protein domain specific binding2181
GO:0042753positive regulation of circadian rhythm17
GO:0006424glutamyl-tRNA aminoacylation12
GO:00427915S class rRNA transcription from RNA polymerase III type 1 promoter26
GO:0019899enzyme binding3288
GO:0001649osteoblast differentiation395
GO:0006360transcription from RNA polymerase I promoter130
GO:0031116positive regulation of microtubule polymerization111
GO:0034644cellular response to UV132
GO:0009749response to glucose264
GO:0005654nucleoplasm311095
GO:0006458'de novo' protein folding13
GO:0042826histone deacetylase binding274
GO:0007507heart development2141
GO:0043995histone acetyltransferase activity (H4-K5 specific)19
GO:0048742regulation of skeletal muscle fiber development15
GO:0009408response to heat240
GO:0018105peptidyl-serine phosphorylation169
GO:0010458exit from mitosis17
GO:0031080nuclear pore outer ring110
GO:0000776kinetochore463
GO:0016149translation release factor activity, codon specific13
GO:0014070response to organic cyclic compound143
GO:0000922spindle pole191
GO:0000502proteasome complex258
GO:0000302response to reactive oxygen species19
GO:0016045detection of bacterium114
GO:0000122negative regulation of transcription from RNA polymerase II promoter10589
GO:0090398cellular senescence120
GO:0071608macrophage inflammatory protein-1 alpha production11
GO:0007163establishment or maintenance of cell polarity124
GO:0065004protein-DNA complex assembly15
GO:0010460positive regulation of heart rate113
GO:0043525positive regulation of neuron apoptotic process246
GO:0046523S-methyl-5-thioribose-1-phosphate isomerase activity14
GO:0051090regulation of sequence-specific DNA binding transcription factor activity120
GO:0071013catalytic step 2 spliceosome379
GO:0006464cellular protein modification process189
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process479
GO:0051301cell division281
GO:0030529ribonucleoprotein complex6114
GO:0033632regulation of cell-cell adhesion mediated by integrin13
GO:0016150translation release factor activity, codon nonspecific11
GO:0046061dATP catabolic process13
GO:0006260DNA replication4125
GO:0043274phospholipase binding117
GO:0006283transcription-coupled nucleotide-excision repair146
GO:0001890placenta development134
GO:0035019somatic stem cell maintenance240
GO:0003690double-stranded DNA binding191
GO:0043558regulation of translational initiation in response to stress12
GO:0017148negative regulation of translation341
GO:0044822poly(A) RNA binding271078
GO:0030374ligand-dependent nuclear receptor transcription coactivator activity143
GO:0010628positive regulation of gene expression2149
GO:0048471perinuclear region of cytoplasm1523
GO:0007275multicellular organismal development1344
GO:0008380RNA splicing14232
GO:0070542response to fatty acid114
GO:0006983ER overload response19
GO:0045787positive regulation of cell cycle123
GO:0006433prolyl-tRNA aminoacylation12
GO:0008143poly(A) binding212
GO:0003723RNA binding15355
GO:0007283spermatogenesis1276
GO:0001190RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription116
GO:0009595detection of biotic stimulus13
GO:0060510Type II pneumocyte differentiation17
GO:2001237negative regulation of extrinsic apoptotic signaling pathway135
GO:0043982histone H4-K8 acetylation115
GO:0051019mitogen-activated protein kinase binding213
GO:0016021integral component of membrane72483
GO:0043022ribosome binding228
GO:0004535poly(A)-specific ribonuclease activity111
GO:0034136negative regulation of toll-like receptor 2 signaling pathway13
GO:0033160positive regulation of protein import into nucleus, translocation111
GO:0061024membrane organization1146
GO:0050905neuromuscular process114
GO:0032403protein complex binding2185
GO:0018345protein palmitoylation120
GO:0000132establishment of mitotic spindle orientation116
GO:0032587ruffle membrane172
GO:0014835myoblast differentiation involved in skeletal muscle regeneration11
GO:0032092positive regulation of protein binding139
GO:2000036regulation of stem cell maintenance111
GO:0014003oligodendrocyte development320
GO:0019907cyclin-dependent protein kinase activating kinase holoenzyme complex16
GO:0048147negative regulation of fibroblast proliferation124
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I277
GO:0071339MLL1 complex127
GO:0030014CCR4-NOT complex115
GO:0030889negative regulation of B cell proliferation114
GO:1903507negative regulation of nucleic acid-templated transcription132
GO:0008079translation termination factor activity11
GO:0005929cilium184
GO:0006333chromatin assembly or disassembly16
GO:0005643nuclear pore359
GO:0009794regulation of mitotic cell cycle, embryonic11
GO:0043278response to morphine121
GO:0004418hydroxymethylbilane synthase activity11
GO:0045879negative regulation of smoothened signaling pathway123
GO:0010793regulation of mRNA export from nucleus15
GO:0003674molecular_function1524
GO:0086010membrane depolarization during action potential125
GO:0051770positive regulation of nitric-oxide synthase biosynthetic process114
GO:0006511ubiquitin-dependent protein catabolic process3127
GO:0043967histone H4 acetylation128
GO:0005868cytoplasmic dynein complex113
GO:0043565sequence-specific DNA binding3365
GO:0050830defense response to Gram-positive bacterium149
GO:0002224toll-like receptor signaling pathway2109
GO:0007254JNK cascade251
GO:0007265Ras protein signal transduction275
GO:0034146toll-like receptor 5 signaling pathway265
GO:0006879cellular iron ion homeostasis157
GO:0006376mRNA splice site selection115
GO:0071222cellular response to lipopolysaccharide281
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway271
GO:0005838proteasome regulatory particle112
GO:0043405regulation of MAP kinase activity15
GO:0006783heme biosynthetic process120
GO:0005515protein binding776127
GO:0050681androgen receptor binding138
GO:0006564L-serine biosynthetic process14
GO:0000777condensed chromosome kinetochore168
GO:0007411axon guidance2327
GO:0006778porphyrin-containing compound metabolic process218
GO:0042326negative regulation of phosphorylation121
GO:0030141secretory granule167
GO:0061141lung ciliated cell differentiation11
GO:0070830tight junction assembly133
GO:0000724double-strand break repair via homologous recombination157
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle474
GO:0006406mRNA export from nucleus562
GO:0006475internal protein amino acid acetylation17
GO:0005487nucleocytoplasmic transporter activity214
GO:0008637apoptotic mitochondrial changes121
GO:0070849response to epidermal growth factor15
GO:0006369termination of RNA polymerase II transcription445
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle470
GO:0019887protein kinase regulator activity14
GO:0004392heme oxygenase (decyclizing) activity12
GO:0034142toll-like receptor 4 signaling pathway296
GO:0042581specific granule112
GO:0019894kinesin binding128
GO:0044324regulation of transcription involved in anterior/posterior axis specification12
GO:0006446regulation of translational initiation236
GO:0051604protein maturation110
GO:0042323negative regulation of circadian sleep/wake cycle, non-REM sleep12
GO:0070374positive regulation of ERK1 and ERK2 cascade1110
GO:0008762UDP-N-acetylmuramate dehydrogenase activity16
GO:0031424keratinization127
GO:0005085guanyl-nucleotide exchange factor activity274
GO:0005737cytoplasm433976
GO:0006289nucleotide-excision repair169
GO:0003407neural retina development15
GO:0006006glucose metabolic process1119
GO:0004832valine-tRNA ligase activity12
GO:0008152metabolic process2302
GO:0006184GTP catabolic process2220
GO:0070664negative regulation of leukocyte proliferation11
GO:0002181cytoplasmic translation16
GO:0016607nuclear speck6175
GO:0003924GTPase activity2203
GO:0005845mRNA cap binding complex111
GO:0060770negative regulation of epithelial cell proliferation involved in prostate gland development17
GO:0005743mitochondrial inner membrane3300
GO:0016055Wnt signaling pathway3141
GO:0030518intracellular steroid hormone receptor signaling pathway114
GO:0000287magnesium ion binding2174
GO:0007077mitotic nuclear envelope disassembly337
GO:0000278mitotic cell cycle12398
GO:0097192extrinsic apoptotic signaling pathway in absence of ligand135
GO:0043194axon initial segment110
GO:1901673regulation of spindle assembly involved in mitosis11
GO:0051010microtubule plus-end binding211
GO:0032886regulation of microtubule-based process112
GO:0008033tRNA processing139
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle365
GO:0016071mRNA metabolic process8223
GO:0006379mRNA cleavage210
GO:0042307positive regulation of protein import into nucleus215
GO:0001829trophectodermal cell differentiation217
GO:0034220ion transmembrane transport1167
GO:0016023cytoplasmic membrane-bounded vesicle1107
GO:0050728negative regulation of inflammatory response160
GO:0046983protein dimerization activity1131
GO:0071354cellular response to interleukin-619
GO:0051988regulation of attachment of spindle microtubules to kinetochore17
GO:0051292nuclear pore complex assembly18
GO:0042493response to drug1288
GO:0005828kinetochore microtubule15
GO:0004708MAP kinase kinase activity113
GO:0006986response to unfolded protein251
GO:0004000adenosine deaminase activity15
GO:0050766positive regulation of phagocytosis124
GO:0007179transforming growth factor beta receptor signaling pathway1130
GO:0008353RNA polymerase II carboxy-terminal domain kinase activity116
GO:0005667transcription factor complex3178
GO:0005829cytosol382562
GO:0006144purine nucleobase metabolic process232
GO:0034138toll-like receptor 3 signaling pathway280
GO:0009890negative regulation of biosynthetic process12
GO:0021960anterior commissure morphogenesis15
GO:0005666DNA-directed RNA polymerase III complex117
GO:0042542response to hydrogen peroxide140
GO:0000775chromosome, centromeric region352
GO:0034273ATG1/UKL1 signaling complex14
GO:0001578microtubule bundle formation120
GO:0050821protein stabilization391
GO:0006383transcription from RNA polymerase III promoter339
GO:0032689negative regulation of interferon-gamma production124
GO:0006385transcription elongation from RNA polymerase III promoter118
GO:0051533positive regulation of NFAT protein import into nucleus14
GO:0019046release from viral latency12
GO:0000339RNA cap binding18
GO:0048011neurotrophin TRK receptor signaling pathway2273
GO:0000188inactivation of MAPK activity127
GO:0007067mitotic nuclear division4231
GO:0004693cyclin-dependent protein serine/threonine kinase activity132
GO:0016485protein processing129
GO:0030968endoplasmic reticulum unfolded protein response281
GO:0005778peroxisomal membrane250
GO:0008609alkylglycerone-phosphate synthase activity11
GO:0035986senescence-associated heterochromatin focus assembly13
GO:0045793positive regulation of cell size19
GO:0045662negative regulation of myoblast differentiation111
GO:0010827regulation of glucose transport331
GO:0005789endoplasmic reticulum membrane2636
GO:0006310DNA recombination267
GO:0002176male germ cell proliferation12
GO:0008334histone mRNA metabolic process112
GO:0019395fatty acid oxidation111
GO:0070937CRD-mediated mRNA stability complex26
GO:0060971embryonic heart tube left/right pattern formation15
GO:0005576extracellular region11049
GO:0006404RNA import into nucleus11
GO:0005720nuclear heterochromatin122
GO:0010942positive regulation of cell death120
GO:0090308regulation of methylation-dependent chromatin silencing11
GO:0005575cellular_component1322
GO:0006157deoxyadenosine catabolic process11
GO:0042803protein homodimerization activity6617
GO:0006563L-serine metabolic process13
GO:0004842ubiquitin-protein transferase activity5256
GO:0003779actin binding1275
GO:0004527exonuclease activity114
GO:0005905coated pit151
GO:0051082unfolded protein binding395
GO:0002925positive regulation of humoral immune response mediated by circulating immunoglobulin15
GO:0090245axis elongation involved in somitogenesis13
GO:0070840dynein complex binding12
GO:0018393internal peptidyl-lysine acetylation14
GO:0009786regulation of asymmetric cell division12
GO:0035725sodium ion transmembrane transport158
GO:0031490chromatin DNA binding139
GO:0001054RNA polymerase I activity211
GO:0000932cytoplasmic mRNA processing body256
GO:0019207kinase regulator activity12
GO:0001502cartilage condensation120
GO:0035457cellular response to interferon-alpha18
GO:0003700sequence-specific DNA binding transcription factor activity10748
GO:0001047core promoter binding246
GO:0060486Clara cell differentiation14
GO:0032757positive regulation of interleukin-8 production121
GO:0034393positive regulation of smooth muscle cell apoptotic process15
GO:0033523histone H2B ubiquitination18
GO:0051592response to calcium ion155
GO:0005851eukaryotic translation initiation factor 2B complex36
GO:0035253ciliary rootlet19
GO:0001554luteolysis12
GO:0008611ether lipid biosynthetic process14
GO:0006355regulation of transcription, DNA-templated131104
GO:0035924cellular response to vascular endothelial growth factor stimulus120
GO:0032261purine nucleotide salvage11
GO:0010606positive regulation of cytoplasmic mRNA processing body assembly15
GO:0031648protein destabilization221
GO:0002020protease binding174
GO:2000111positive regulation of macrophage apoptotic process13
GO:0000187activation of MAPK activity290
GO:0005813centrosome4339
GO:0046638positive regulation of alpha-beta T cell differentiation19
GO:1990440positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress12
GO:0042692muscle cell differentiation134
GO:0009986cell surface4422
GO:0010467gene expression27669
GO:0003713transcription coactivator activity7239
GO:0001883purine nucleoside binding12
GO:0034166toll-like receptor 10 signaling pathway265
GO:0042981regulation of apoptotic process3151
GO:0007049cell cycle4177
GO:0051015actin filament binding197
GO:0019079viral genome replication112
GO:0019903protein phosphatase binding163
GO:0007166cell surface receptor signaling pathway1149
GO:0007601visual perception1168
GO:0031111negative regulation of microtubule polymerization or depolymerization12
GO:0008584male gonad development177
GO:0070062extracellular vesicular exosome152516
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway125
GO:0004197cysteine-type endopeptidase activity152
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process277
GO:0050908detection of light stimulus involved in visual perception115
GO:0005506iron ion binding1127
GO:0051151negative regulation of smooth muscle cell differentiation14
GO:0001103RNA polymerase II repressing transcription factor binding127
GO:0060765regulation of androgen receptor signaling pathway19
GO:0061025membrane fusion126
GO:0005739mitochondrion161046
GO:0006814sodium ion transport155
GO:0043388positive regulation of DNA binding124
GO:0042552myelination236
GO:0000902cell morphogenesis151
GO:0044295axonal growth cone113
GO:0050434positive regulation of viral transcription244
GO:0008432JUN kinase binding16
GO:0019706protein-cysteine S-palmitoyltransferase activity123
GO:0007417central nervous system development2101
GO:0071224cellular response to peptidoglycan14
GO:0009887organ morphogenesis189
GO:0097194execution phase of apoptosis120
GO:0034080CENP-A containing nucleosome assembly227
GO:0050862positive regulation of T cell receptor signaling pathway17
GO:0035731dinitrosyl-iron complex binding11
GO:0001942hair follicle development135
GO:0018160peptidyl-pyrromethane cofactor linkage11
GO:0038066p38MAPK cascade11
GO:0051260protein homooligomerization1150
GO:0004768stearoyl-CoA 9-desaturase activity13
GO:0046696lipopolysaccharide receptor complex15
GO:0006378mRNA polyadenylation222
GO:0006301postreplication repair17
GO:0051259protein oligomerization141
GO:0070372regulation of ERK1 and ERK2 cascade117
GO:0006479protein methylation215
GO:0042771intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator130
GO:0005680anaphase-promoting complex120
GO:0045296cadherin binding125
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity126
GO:0048188Set1C/COMPASS complex19
GO:0001953negative regulation of cell-matrix adhesion112
GO:0006461protein complex assembly2111
GO:0003747translation release factor activity24
GO:0071456cellular response to hypoxia298
GO:0030331estrogen receptor binding227
GO:0031072heat shock protein binding133
GO:0006965positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria12
GO:0071407cellular response to organic cyclic compound339
GO:0045202synapse1140
GO:0033147negative regulation of intracellular estrogen receptor signaling pathway210
GO:0043984histone H4-K16 acetylation119
GO:0004402histone acetyltransferase activity143
GO:0050870positive regulation of T cell activation117
GO:0048565digestive tract development127
GO:0001731formation of translation preinitiation complex117
GO:0006887exocytosis169
GO:0004647phosphoserine phosphatase activity14
GO:0019898extrinsic component of membrane146
GO:0043025neuronal cell body3254
GO:0090090negative regulation of canonical Wnt signaling pathway488
GO:0048541Peyer's patch development19
GO:0005887integral component of plasma membrane1961
GO:0046040IMP metabolic process13
GO:2000791negative regulation of mesenchymal cell proliferation involved in lung development12
GO:0006282regulation of DNA repair17
GO:0006363termination of RNA polymerase I transcription124
GO:0005925focal adhesion2370
GO:0032057negative regulation of translational initiation in response to stress15
GO:0005764lysosome1182
GO:0042752regulation of circadian rhythm337
GO:0003887DNA-directed DNA polymerase activity129
GO:0009954proximal/distal pattern formation121
GO:0007519skeletal muscle tissue development241
GO:0010944negative regulation of transcription by competitive promoter binding110
GO:0030324lung development176
GO:2000629negative regulation of miRNA metabolic process11
GO:0036124histone H3-K9 trimethylation15
GO:0007094mitotic spindle assembly checkpoint331
GO:0071204histone pre-mRNA 3'end processing complex16
GO:0051294establishment of spindle orientation12
GO:0051123RNA polymerase II transcriptional preinitiation complex assembly12
GO:0006401RNA catabolic process115
GO:0016070RNA metabolic process8247
GO:0006397mRNA processing6169
GO:0031453positive regulation of heterochromatin assembly11
GO:0030234enzyme regulator activity113
GO:0043434response to peptide hormone246
GO:0044212transcription regulatory region DNA binding5171
GO:0007568aging2123
GO:0035497cAMP response element binding16
GO:0070534protein K63-linked ubiquitination131
GO:0016323basolateral plasma membrane1149
GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activity277
GO:0090316positive regulation of intracellular protein transport118
GO:0060444branching involved in mammary gland duct morphogenesis113
GO:0016874ligase activity4224
GO:0050700CARD domain binding18
GO:0032465regulation of cytokinesis114
GO:1902476chloride transmembrane transport170
GO:0005815microtubule organizing center1110
GO:0015630microtubule cytoskeleton1112
GO:0043425bHLH transcription factor binding124
GO:0035198miRNA binding113
GO:0043281regulation of cysteine-type endopeptidase activity involved in apoptotic process112
GO:0055086nucleobase-containing small molecule metabolic process273
GO:0005525GTP binding5328
GO:0032993protein-DNA complex114
GO:0042113B cell activation125
GO:0010494cytoplasmic stress granule230
GO:1990090cellular response to nerve growth factor stimulus115
GO:0010831positive regulation of myotube differentiation18
GO:0000281mitotic cytokinesis121
GO:0044615nuclear pore nuclear basket14
GO:0032735positive regulation of interleukin-12 production225
GO:0030659cytoplasmic vesicle membrane1107
GO:0060205cytoplasmic membrane-bounded vesicle lumen13
GO:2000379positive regulation of reactive oxygen species metabolic process124
GO:0032495response to muramyl dipeptide29
GO:0033089positive regulation of T cell differentiation in thymus18
GO:0016779nucleotidyltransferase activity18
GO:0034707chloride channel complex140
GO:0048511rhythmic process247
GO:0050679positive regulation of epithelial cell proliferation154
GO:0030425dendrite1240
GO:0032872regulation of stress-activated MAPK cascade18
GO:0035371microtubule plus-end114
GO:0034453microtubule anchoring112
GO:0044255cellular lipid metabolic process1140
GO:0030858positive regulation of epithelial cell differentiation16
GO:0002199zona pellucida receptor complex110
GO:0042110T cell activation243
GO:0008021synaptic vesicle273
GO:0030027lamellipodium1130
GO:0071549cellular response to dexamethasone stimulus120
GO:0043005neuron projection4161
GO:0007140male meiosis113
GO:0006606protein import into nucleus130
GO:0045667regulation of osteoblast differentiation110
GO:0006396RNA processing460
GO:0003688DNA replication origin binding16
GO:0006430lysyl-tRNA aminoacylation11
GO:0042809vitamin D receptor binding115
GO:0090267positive regulation of mitotic cell cycle spindle assembly checkpoint16
GO:0006521regulation of cellular amino acid metabolic process250
GO:0051087chaperone binding159
GO:0002842positive regulation of T cell mediated immune response to tumor cell11
GO:0000778condensed nuclear chromosome kinetochore14
GO:0007026negative regulation of microtubule depolymerization216
GO:0005975carbohydrate metabolic process3274
GO:0006611protein export from nucleus125
GO:0009168purine ribonucleoside monophosphate biosynthetic process212
GO:0000786nucleosome170
GO:0042582azurophil granule18
GO:0002128tRNA nucleoside ribose methylation11
GO:0017075syntaxin-1 binding119
GO:0008135translation factor activity, nucleic acid binding224
GO:0032874positive regulation of stress-activated MAPK cascade112
GO:0061136regulation of proteasomal protein catabolic process112
GO:0002381immunoglobulin production involved in immunoglobulin mediated immune response16
GO:0004674protein serine/threonine kinase activity2312
GO:0033268node of Ranvier116
GO:0000079regulation of cyclin-dependent protein serine/threonine kinase activity147
GO:0042754negative regulation of circadian rhythm18
GO:0010804negative regulation of tumor necrosis factor-mediated signaling pathway19
GO:0005881cytoplasmic microtubule241
GO:0097157pre-mRNA intronic binding14
GO:0004468lysine N-acetyltransferase activity, acting on acetyl phosphate as donor15
GO:0031990mRNA export from nucleus in response to heat stress12
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway271
GO:0045947negative regulation of translational initiation112
GO:0097452GAIT complex24
GO:0015030Cajal body145
GO:2000016negative regulation of determination of dorsal identity11
GO:1901985positive regulation of protein acetylation11
GO:0070979protein K11-linked ubiquitination126
GO:00084095'-3' exonuclease activity19
GO:0070934CRD-mediated mRNA stabilization25
GO:0004019adenylosuccinate synthase activity12
GO:0001822kidney development279
GO:00709353'-UTR-mediated mRNA stabilization112
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process119
GO:0018076N-terminal peptidyl-lysine acetylation13
GO:0009416response to light stimulus113
GO:0051781positive regulation of cell division139
GO:0032496response to lipopolysaccharide1122
GO:0032720negative regulation of tumor necrosis factor production227
GO:0006368transcription elongation from RNA polymerase II promoter367
GO:0007340acrosome reaction111
GO:0005849mRNA cleavage factor complex15
GO:0070064proline-rich region binding118
GO:0001889liver development282
GO:0006531aspartate metabolic process16
GO:0032727positive regulation of interferon-alpha production111
GO:0001955blood vessel maturation18
GO:0044325ion channel binding177
GO:0046974histone methyltransferase activity (H3-K9 specific)16
GO:0060509Type I pneumocyte differentiation16
GO:0016020membrane271746
GO:0032930positive regulation of superoxide anion generation17
GO:0048103somatic stem cell division19
GO:0070816phosphorylation of RNA polymerase II C-terminal domain12
GO:0035259glucocorticoid receptor binding19
GO:0019005SCF ubiquitin ligase complex129
GO:0000939condensed chromosome inner kinetochore12
GO:0009611response to wounding153
GO:0016337single organismal cell-cell adhesion192
GO:0000077DNA damage checkpoint128
GO:0051262protein tetramerization130
GO:0007000nucleolus organization14
GO:0045648positive regulation of erythrocyte differentiation121
GO:0007628adult walking behavior129
GO:0016328lateral plasma membrane146
GO:0048291isotype switching to IgG isotypes11
GO:0006351transcription, DNA-templated171585
GO:0003676nucleic acid binding2122
GO:0032500muramyl dipeptide binding11
GO:0005615extracellular space41010
GO:0016477cell migration2131
GO:0071260cellular response to mechanical stimulus166
GO:0071459protein localization to chromosome, centromeric region13
GO:0040008regulation of growth151
GO:0031124mRNA 3'-end processing442
GO:0032691negative regulation of interleukin-1 beta production16
GO:0030018Z disc298
GO:0006903vesicle targeting18
GO:0070301cellular response to hydrogen peroxide141
GO:0097057TRAF2-GSTP1 complex11
GO:0043032positive regulation of macrophage activation110
GO:0045862positive regulation of proteolysis221
GO:0006805xenobiotic metabolic process1129
GO:0090399replicative senescence110
GO:0046103inosine biosynthetic process12
GO:0010560positive regulation of glycoprotein biosynthetic process13
GO:0009952anterior/posterior pattern specification284
GO:0060041retina development in camera-type eye153
GO:0051146striated muscle cell differentiation112
GO:0055105ubiquitin-protein transferase inhibitor activity12
GO:0060965negative regulation of gene silencing by miRNA12
GO:0071320cellular response to cAMP142
GO:0007050cell cycle arrest3126
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia126
GO:0005254chloride channel activity141
GO:0043488regulation of mRNA stability113
GO:0010001glial cell differentiation113
GO:0042483negative regulation of odontogenesis11
GO:0005839proteasome core complex118
GO:0050727regulation of inflammatory response147
GO:0071158positive regulation of cell cycle arrest119
GO:0046872metal ion binding61465
GO:0044297cell body146
GO:0031519PcG protein complex125
GO:0006200ATP catabolic process1303
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest365
GO:0043101purine-containing compound salvage110
GO:0034660ncRNA metabolic process123
GO:0045295gamma-catenin binding112
GO:0050850positive regulation of calcium-mediated signaling120
GO:0032481positive regulation of type I interferon production261
GO:0030335positive regulation of cell migration2130
GO:0007596blood coagulation1464
GO:0002606positive regulation of dendritic cell antigen processing and presentation17
GO:0004521endoribonuclease activity17
GO:0032760positive regulation of tumor necrosis factor production137
GO:0060795cell fate commitment involved in formation of primary germ layer11
GO:0005736DNA-directed RNA polymerase I complex212
GO:0005640nuclear outer membrane123
GO:0000189MAPK import into nucleus12
GO:0042802identical protein binding6491
GO:0033598mammary gland epithelial cell proliferation19
GO:0043981histone H4-K5 acetylation115
GO:0006334nucleosome assembly379
GO:0071333cellular response to glucose stimulus135
GO:0007155cell adhesion2384
GO:0015758glucose transport359
GO:0043392negative regulation of DNA binding127
GO:0031592centrosomal corona11
GO:0032733positive regulation of interleukin-10 production219
GO:0019773proteasome core complex, alpha-subunit complex18
GO:0017091AU-rich element binding215
GO:0097165nuclear stress granule11
GO:0005671Ada2/Gcn5/Ada3 transcription activator complex115
GO:0051771negative regulation of nitric-oxide synthase biosynthetic process14
GO:0045893positive regulation of transcription, DNA-templated6487
GO:0045773positive regulation of axon extension118
GO:0010225response to UV-C210
GO:0097167circadian regulation of translation14
GO:0005516calmodulin binding1162
GO:0019908nuclear cyclin-dependent protein kinase holoenzyme complex13
GO:1903377negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway14
GO:0001701in utero embryonic development2210
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription162
GO:0050714positive regulation of protein secretion129
GO:0000086G2/M transition of mitotic cell cycle3137
GO:0043154negative regulation of cysteine-type endopeptidase activity involved in apoptotic process163
GO:0007162negative regulation of cell adhesion133
GO:0019509L-methionine biosynthetic process from methylthioadenosine19
GO:0032740positive regulation of interleukin-17 production111
GO:0045292mRNA cis splicing, via spliceosome15
GO:0045454cell redox homeostasis152
GO:0044267cellular protein metabolic process7495
GO:0005684U2-type spliceosomal complex12
GO:0014850response to muscle activity19
GO:0030890positive regulation of B cell proliferation135
GO:0090503RNA phosphodiester bond hydrolysis, exonucleolytic126
GO:0002674negative regulation of acute inflammatory response17
GO:0048306calcium-dependent protein binding157
GO:0032729positive regulation of interferon-gamma production139
GO:0005856cytoskeleton2311
GO:0000910cytokinesis151
GO:0030981cortical microtubule cytoskeleton12
GO:0070373negative regulation of ERK1 and ERK2 cascade131
GO:0051171regulation of nitrogen compound metabolic process11
GO:0010389regulation of G2/M transition of mitotic cell cycle19
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent273
GO:0001843neural tube closure175
GO:0005215transporter activity2145
GO:0005777peroxisome190
GO:0043547positive regulation of GTPase activity2190
GO:0006405RNA export from nucleus13
GO:0001824blastocyst development115
GO:0002636positive regulation of germinal center formation14
GO:0030914STAGA complex113
GO:0004824lysine-tRNA ligase activity11
GO:0002756MyD88-independent toll-like receptor signaling pathway278
GO:0016407acetyltransferase activity110
GO:0021740principal sensory nucleus of trigeminal nerve development11
GO:0048538thymus development136
GO:0070431nucleotide-binding oligomerization domain containing 2 signaling pathway15
GO:0004045aminoacyl-tRNA hydrolase activity13
GO:0006928cellular component movement192
GO:0051059NF-kappaB binding225
GO:0000387spliceosomal snRNP assembly127
GO:0046966thyroid hormone receptor binding126
GO:0043491protein kinase B signaling132
GO:0042162telomeric DNA binding111
GO:0016409palmitoyltransferase activity117
GO:0000123histone acetyltransferase complex221
GO:0004871signal transducer activity1216
GO:0004827proline-tRNA ligase activity12
GO:0006457protein folding1149
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding3168
GO:0003729mRNA binding373
GO:0045736negative regulation of cyclin-dependent protein serine/threonine kinase activity219
GO:0015966diadenosine tetraphosphate biosynthetic process12
GO:0002062chondrocyte differentiation232
GO:0071479cellular response to ionizing radiation125
GO:0001056RNA polymerase III activity116
GO:0006412translation5235
GO:0043536positive regulation of blood vessel endothelial cell migration117
GO:0000400four-way junction DNA binding19
GO:0010468regulation of gene expression172
GO:0030178negative regulation of Wnt signaling pathway136
GO:0000780condensed nuclear chromosome, centromeric region18
GO:0032695negative regulation of interleukin-12 production112
GO:0006999nuclear pore organization14
GO:0045727positive regulation of translation246
GO:0030521androgen receptor signaling pathway141
GO:0033088negative regulation of immature T cell proliferation in thymus14
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activity293
GO:0005681spliceosomal complex183
GO:0033574response to testosterone122
GO:0030135coated vesicle13
GO:0006633fatty acid biosynthetic process137
GO:0043231intracellular membrane-bounded organelle1332
GO:0030308negative regulation of cell growth2113
GO:0043254regulation of protein complex assembly18
GO:0000288nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay253
GO:0034605cellular response to heat129
GO:0042975peroxisome proliferator activated receptor binding111
GO:0060749mammary gland alveolus development115
GO:0001530lipopolysaccharide binding113
GO:0046645positive regulation of gamma-delta T cell activation11
GO:0035690cellular response to drug250
GO:0005874microtubule3258
GO:0035666TRIF-dependent toll-like receptor signaling pathway276
GO:0060298positive regulation of sarcomere organization15
GO:0016787hydrolase activity170
GO:0035984cellular response to trichostatin A12
GO:0033613activating transcription factor binding118
GO:0016887ATPase activity1144
GO:0004364glutathione transferase activity121
GO:0072686mitotic spindle129
GO:0022624proteasome accessory complex117
GO:0005782peroxisomal matrix131
GO:0045987positive regulation of smooth muscle contraction115
GO:0003684damaged DNA binding151
GO:0071897DNA biosynthetic process129
GO:0019827stem cell maintenance248
GO:0003777microtubule motor activity160
GO:0016575histone deacetylation121
GO:0051403stress-activated MAPK cascade254
GO:0032755positive regulation of interleukin-6 production236
GO:0043330response to exogenous dsRNA130
GO:0042834peptidoglycan binding19
GO:0042382paraspeckles26
GO:0048593camera-type eye morphogenesis117
GO:0006357regulation of transcription from RNA polymerase II promoter4275
GO:0031514motile cilium142
GO:0005819spindle2114
GO:0016311dephosphorylation194
GO:0043124negative regulation of I-kappaB kinase/NF-kappaB signaling130
GO:0004252serine-type endopeptidase activity1119
GO:0046827positive regulation of protein export from nucleus113
GO:0005634nucleus554828
GO:0060391positive regulation of SMAD protein import into nucleus111
GO:0006417regulation of translation163
GO:0070256negative regulation of mucus secretion12
GO:0035257nuclear hormone receptor binding119
GO:0031016pancreas development122
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling1148
GO:0060762regulation of branching involved in mammary gland duct morphogenesis16
GO:0004861cyclin-dependent protein serine/threonine kinase inhibitor activity112
GO:0002368B cell cytokine production11
GO:0031667response to nutrient levels119
GO:0001714endodermal cell fate specification15
GO:0008233peptidase activity155
GO:0004672protein kinase activity1178
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway143
GO:0036123histone H3-K9 dimethylation13
GO:0008610lipid biosynthetic process110
GO:0006386termination of RNA polymerase III transcription118
GO:0009953dorsal/ventral pattern formation132
GO:0043122regulation of I-kappaB kinase/NF-kappaB signaling111
GO:0007091metaphase/anaphase transition of mitotic cell cycle17
GO:0006418tRNA aminoacylation for protein translation342
GO:0045663positive regulation of myoblast differentiation111
GO:0090022regulation of neutrophil chemotaxis13
GO:0007422peripheral nervous system development127
GO:0051716cellular response to stimulus24
GO:0035329hippo signaling126
GO:0042405nuclear inclusion body19
GO:0015631tubulin binding129
GO:0005730nucleolus281684
GO:0019228neuronal action potential118
GO:0006935chemotaxis1108
GO:0006874cellular calcium ion homeostasis176
GO:0005886plasma membrane142834
GO:0000226microtubule cytoskeleton organization255
GO:0097153cysteine-type endopeptidase activity involved in apoptotic process15
GO:0001055RNA polymerase II activity18
GO:0031274positive regulation of pseudopodium assembly110
GO:0071480cellular response to gamma radiation114
GO:0046825regulation of protein export from nucleus27
GO:0008645hexose transport342
GO:2000774positive regulation of cellular senescence14
GO:0006913nucleocytoplasmic transport127
GO:0005509calcium ion binding1589
GO:0002755MyD88-dependent toll-like receptor signaling pathway380
GO:0000338protein deneddylation13
GO:0009267cellular response to starvation136
GO:0097190apoptotic signaling pathway1116
GO:0043407negative regulation of MAP kinase activity134
GO:0043103hypoxanthine salvage13
GO:0019901protein kinase binding4320
GO:0006541glutamine metabolic process118
GO:0043578nuclear matrix organization11
GO:0030864cortical actin cytoskeleton125
GO:0009791post-embryonic development175
GO:0003823antigen binding128
GO:0032790ribosome disassembly17
GO:0000209protein polyubiquitination5116
GO:0042974retinoic acid receptor binding113
GO:0050718positive regulation of interleukin-1 beta secretion118
GO:0035732nitric oxide storage11
GO:0043620regulation of DNA-templated transcription in response to stress15
GO:0035726common myeloid progenitor cell proliferation13
GO:0042176regulation of protein catabolic process116
GO:00063707-methylguanosine mRNA capping230
GO:0016567protein ubiquitination5299
GO:0045785positive regulation of cell adhesion141
GO:0046982protein heterodimerization activity3399
GO:0006403RNA localization12
GO:0071225cellular response to muramyl dipeptide13
GO:0006450regulation of translational fidelity110
GO:0009368endopeptidase Clp complex12
GO:0032498detection of muramyl dipeptide11
GO:0051924regulation of calcium ion transport122
GO:0007584response to nutrient172
GO:0016592mediator complex535
GO:0031398positive regulation of protein ubiquitination152
GO:2000795negative regulation of epithelial cell proliferation involved in lung morphogenesis11
GO:0010965regulation of mitotic sister chromatid separation11
GO:0016363nuclear matrix592
GO:0044337canonical Wnt signaling pathway involved in positive regulation of apoptotic process12
GO:0006167AMP biosynthetic process14
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process276
GO:0031647regulation of protein stability230
GO:0008175tRNA methyltransferase activity12
GO:0006892post-Golgi vesicle-mediated transport144
GO:0005665DNA-directed RNA polymerase II, core complex116
GO:0005685U1 snRNP114
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity259
GO:0071346cellular response to interferon-gamma223
GO:0003743translation initiation factor activity549
GO:0005913cell-cell adherens junction129
GO:0033197response to vitamin E19
GO:0071850mitotic cell cycle arrest111
GO:0071257cellular response to electrical stimulus111
GO:0016746transferase activity, transferring acyl groups216
GO:0042306regulation of protein import into nucleus13
GO:0060744mammary gland branching involved in thelarche16
GO:0006915apoptotic process8571
GO:0005846nuclear cap binding complex12
GO:0006413translational initiation4131
GO:0001106RNA polymerase II transcription corepressor activity122
GO:0060070canonical Wnt signaling pathway275
GO:0034612response to tumor necrosis factor128
GO:2000323negative regulation of glucocorticoid receptor signaling pathway16
GO:0048024regulation of mRNA splicing, via spliceosome16
GO:0005759mitochondrial matrix4233
GO:0030321transepithelial chloride transport15
GO:0048675axon extension121
GO:0002161aminoacyl-tRNA editing activity17
GO:0033077T cell differentiation in thymus133
GO:0009636response to toxic substance166
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding144
GO:0070688MLL5-L complex18
GO:0004707MAP kinase activity111
GO:0071949FAD binding110
GO:0033503HULC complex14
GO:0008088axon cargo transport110
GO:0006438valyl-tRNA aminoacylation12
GO:0007517muscle organ development183
GO:0043996histone acetyltransferase activity (H4-K8 specific)19
GO:0006325chromatin organization3123
GO:0046332SMAD binding140
GO:0005198structural molecule activity1159
GO:0042026protein refolding115
GO:0002686negative regulation of leukocyte migration15
GO:0051603proteolysis involved in cellular protein catabolic process116
GO:0004416hydroxyacylglutathione hydrolase activity12
GO:1900153positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay110
GO:0044300cerebellar mossy fiber16
GO:0016604nuclear body131
GO:0090081regulation of heart induction by regulation of canonical Wnt signaling pathway11
GO:0046111xanthine biosynthetic process11
GO:0006782protoporphyrinogen IX biosynthetic process19
GO:2001235positive regulation of apoptotic signaling pathway128
GO:0035914skeletal muscle cell differentiation142
GO:0034641cellular nitrogen compound metabolic process3177
GO:0019221cytokine-mediated signaling pathway3230
GO:0071389cellular response to mineralocorticoid stimulus12
GO:0048566embryonic digestive tract development114
GO:0010390histone monoubiquitination111
GO:0035613RNA stem-loop binding14
GO:0005635nuclear envelope3116
GO:0042742defense response to bacterium170
GO:0006921cellular component disassembly involved in execution phase of apoptosis147
GO:0046832negative regulation of RNA export from nucleus12
GO:0006987activation of signaling protein activity involved in unfolded protein response262
GO:0005923tight junction192
GO:0008270zinc ion binding111067
GO:0051382kinetochore assembly110
GO:1901687glutathione derivative biosynthetic process123
GO:0002710negative regulation of T cell mediated immunity11
GO:0006281DNA repair4264
GO:0001669acrosomal vesicle151
GO:0000127transcription factor TFIIIC complex26
GO:0070026nitric oxide binding11
GO:0031023microtubule organizing center organization15
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic132
GO:0060213positive regulation of nuclear-transcribed mRNA poly(A) tail shortening111
GO:0097371MDM2/MDM4 family protein binding15
GO:0031625ubiquitin protein ligase binding2180
GO:0005850eukaryotic translation initiation factor 2 complex23
GO:0033235positive regulation of protein sumoylation111
GO:0007420brain development1172
GO:0043923positive regulation by host of viral transcription111
GO:0034696response to prostaglandin F12
GO:0060766negative regulation of androgen receptor signaling pathway113
GO:0060177regulation of angiotensin metabolic process11
GO:0015031protein transport2357
GO:0090400stress-induced premature senescence13
GO:0008285negative regulation of cell proliferation4367
GO:0031965nuclear membrane1176
GO:0005622intracellular2226
GO:0007178transmembrane receptor protein serine/threonine kinase signaling pathway111
GO:0035413positive regulation of catenin import into nucleus111
GO:0006364rRNA processing296
GO:0003899DNA-directed RNA polymerase activity125
GO:0006788heme oxidation12
GO:0070244negative regulation of thymocyte apoptotic process18
GO:0005637nuclear inner membrane128
GO:0007219Notch signaling pathway2125
GO:0046972histone acetyltransferase activity (H4-K16 specific)19
GO:0007399nervous system development3245
GO:0005524ATP binding131354
GO:0006398histone mRNA 3'-end processing15
GO:2000110negative regulation of macrophage apoptotic process14
GO:0044281small molecule metabolic process121295
GO:0017101aminoacyl-tRNA synthetase multienzyme complex13
GO:0035985senescence-associated heterochromatin focus13
GO:0007020microtubule nucleation114
GO:0046716muscle cell cellular homeostasis116
GO:0043234protein complex4300
GO:0005844polysome225
GO:0050731positive regulation of peptidyl-tyrosine phosphorylation175
GO:0006338chromatin remodeling168
GO:0034976response to endoplasmic reticulum stress152
GO:0030054cell junction3356
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription2151
GO:0042167heme catabolic process16
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process111
GO:0000731DNA synthesis involved in DNA repair110
GO:0005095GTPase inhibitor activity114
GO:0003682chromatin binding7334
GO:0034045pre-autophagosomal structure membrane112
GO:0032731positive regulation of interleukin-1 beta production17
GO:0000049tRNA binding136
GO:0001541ovarian follicle development137
GO:0007409axonogenesis166
GO:0014737positive regulation of muscle atrophy12
GO:0007010cytoskeleton organization196
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding154
GO:0051209release of sequestered calcium ion into cytosol226
GO:0051525NFAT protein binding15
GO:0008652cellular amino acid biosynthetic process117
GO:0003714transcription corepressor activity5179
GO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic process154
GO:0042301phosphate ion binding111
GO:0071679commissural neuron axon guidance16
GO:0043495protein anchor19
GO:0055085transmembrane transport5514
GO:0030182neuron differentiation177
GO:0051276chromosome organization216
GO:0043409negative regulation of MAPK cascade213
GO:0002862negative regulation of inflammatory response to antigenic stimulus16
GO:0007605sensory perception of sound1111
GO:0031442positive regulation of mRNA 3'-end processing15
GO:0048286lung alveolus development134
GO:0033600negative regulation of mammary gland epithelial cell proliferation15
GO:0006290pyrimidine dimer repair14
GO:0051444negative regulation of ubiquitin-protein transferase activity17
GO:0046330positive regulation of JNK cascade155
GO:0016597amino acid binding120
GO:0006449regulation of translational termination15
GO:0005762mitochondrial large ribosomal subunit115
GO:1901741positive regulation of myoblast fusion15
GO:0033017sarcoplasmic reticulum membrane128
GO:0002906negative regulation of mature B cell apoptotic process14
GO:0002732positive regulation of dendritic cell cytokine production11
GO:0044208'de novo' AMP biosynthetic process13
GO:0035730S-nitrosoglutathione binding11
GO:0001227RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription120
GO:0071300cellular response to retinoic acid156
GO:0006749glutathione metabolic process129
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding175
GO:0003130BMP signaling pathway involved in heart induction13
GO:0005770late endosome194
GO:0000389mRNA 3'-splice site recognition15
GO:2000363positive regulation of prostaglandin-E synthase activity11
GO:0005832chaperonin-containing T-complex19
GO:0007339binding of sperm to zona pellucida127
GO:0032701negative regulation of interleukin-18 production11
GO:0000166nucleotide binding6272
GO:0035234ectopic germ cell programmed cell death17
GO:0048671negative regulation of collateral sprouting15
GO:0006415translational termination287
GO:0000785chromatin273
GO:0001104RNA polymerase II transcription cofactor activity333
GO:0060407negative regulation of penile erection11
GO:0006469negative regulation of protein kinase activity265
GO:0034399nuclear periphery112
GO:0002830positive regulation of type 2 immune response15
GO:0008013beta-catenin binding460
GO:0002944cyclin K-CDK12 complex12
GO:0005938cell cortex1109
GO:0030877beta-catenin destruction complex110
GO:0045807positive regulation of endocytosis114
GO:0045471response to ethanol188
GO:0036464cytoplasmic ribonucleoprotein granule122
GO:0031663lipopolysaccharide-mediated signaling pathway129
GO:0050871positive regulation of B cell activation14
GO:0043515kinetochore binding14
GO:0006508proteolysis2410
GO:0042770signal transduction in response to DNA damage111
GO:0044130negative regulation of growth of symbiont in host117
GO:0000082G1/S transition of mitotic cell cycle4150
GO:0001205RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription222
GO:0002192IRES-dependent translational initiation14
GO:0009798axis specification12
GO:0005876spindle microtubule134
GO:0060585positive regulation of prostaglandin-endoperoxide synthase activity13
GO:0001821histamine secretion14
GO:0032025response to cobalt ion15
GO:0051131chaperone-mediated protein complex assembly113
GO:0005794Golgi apparatus1650
GO:0045732positive regulation of protein catabolic process151
GO:0005248voltage-gated sodium channel activity116
GO:0006750glutathione biosynthetic process110