meta-int-snw-90019

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-27130 chia-screen-data-Fav 2.286 1.02e-07 2.70e-02 2.12e-02 18 13
int-snw-90019 chia-screen-data-Fav 2.833 1.75e-15 4.97e-04 3.45e-03 12 11
reg-snw-11051 chia-screen-data-Fav 2.307 7.93e-08 2.35e-02 1.87e-02 25 17
chia-screen-data-Fav-meta-int-snw-90019 subnetwork

Genes (39)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Chia-Hits Primary Chia-Hits Secondary
PHB 5245 12-2.7432.689163YesYes
MED28 80306 6-2.4042.44586Yes-
CBLL1 79872 6-1.8972.44538--
MED13L 23389 8-2.5502.30750Yes-
VARS 7407 8-2.3662.689204Yes-
SCD 6319 2-1.7152.28682--
APC 324 6-2.2933.004384Yes-
POU5F1 5460 12-5.1483.538179YesYes
NUP160 23279 2-1.5292.38750--
INVS 27130 2-1.1402.28629--
ADA 100 2-2.4992.3078YesYes
FBXO22 26263 8-1.7392.459208--
EIF2S2 8894 9-2.9992.459103YesYes
HNRNPD 3184 3-2.1533.117123Yes-
CENPQ 55166 2-2.1372.45916Yes-
ETF1 2107 7-2.8292.50377YesYes
CCT7 10574 10-2.3352.459173Yes-
CPSF3 51692 7-2.6862.50331YesYes
HNRNPU 3192 12-2.8692.644172Yes-
PRPF40A 55660 4-1.5112.307305--
NDUFA4L2 56901 10-2.4772.45921Yes-
AGPS 8540 6-2.4242.41027YesYes
NFIA 4774 2-1.4582.30780--
YAP1 10413 12-4.2563.53853Yes-
NFIB 4781 2-1.5052.30740--
MATR3 9782 2-1.5562.32947--
ULK2 9706 3-2.2923.197312YesYes
EPRS 2058 2-1.2862.286139--
TPR 7175 3-2.6382.44564YesYes
NCBP1 4686 8-2.5102.45984YesYes
NUDT21 11051 2-1.2732.30761--
SYNCRIP 10492 8-2.4012.503247YesYes
EIF2S1 1965 2-1.8012.41063--
SRSF3 6428 5-2.9923.53854Yes-
GPS1 2873 10-3.6212.68962YesYes
POLH 5429 8-2.5862.45924YesYes
DDIT3 1649 11-2.8253.504343YesYes
SYT8 90019 3-1.3822.8331--
PSPH 5723 2-2.0632.38711Yes-

Interactions (73)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
EPRS 2058 HNRNPU 3192 pd > reg.ITFP.txt: no annot
ETF1 2107 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
APC 324 CCT7 10574 pp -- int.I2D: Jorgensen_EphR, SOURAV_MAPK_LOW, IntAct
EIF2S1 1965 ETF1 2107 pd > reg.ITFP.txt: no annot
EIF2S1 1965 ETF1 2107 pp -- int.I2D: YeastLow
APC 324 PHB 5245 pp -- int.I2D: Jorgensen_EphR
NUDT21 11051 PRPF40A 55660 pd < reg.ITFP.txt: no annot
ULK2 9706 SYNCRIP 10492 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
NCBP1 4686 TPR 7175 pd < reg.ITFP.txt: no annot
NUP160 23279 INVS 27130 pd < reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
HNRNPU 3192 MATR3 9782 pd < reg.ITFP.txt: no annot
EPRS 2058 NUP160 23279 pd > reg.ITFP.txt: no annot
APC 324 TPR 7175 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, IntAct, SOURAV_MAPK_HIGH
EPRS 2058 CCT7 10574 pd > reg.ITFP.txt: no annot
EPRS 2058 INVS 27130 pd <> reg.ITFP.txt: no annot
HNRNPD 3184 ULK2 9706 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
NCBP1 4686 CBLL1 79872 pd < reg.ITFP.txt: no annot
CCT7 10574 FBXO22 26263 pd < reg.ITFP.txt: no annot
CBLL1 79872 MED28 80306 pd > reg.ITFP.txt: no annot
PSPH 5723 FBXO22 26263 pd < reg.ITFP.txt: no annot
EIF2S1 1965 SYNCRIP 10492 pd <> reg.ITFP.txt: no annot
ULK2 9706 MATR3 9782 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
POU5F1 5460 MATR3 9782 pp -- int.I2D: BioGrid_Mouse, IntAct_Mouse
HNRNPU 3192 ULK2 9706 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
DDIT3 1649 HNRNPU 3192 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPU 3192 YAP1 10413 pp -- int.I2D: HPRD;
int.HPRD: in vitro, in vivo
CCT7 10574 PRPF40A 55660 pp -- int.I2D: BioGrid, Pawson1
NFIB 4781 NUDT21 11051 pd > reg.ITFP.txt: no annot
HNRNPU 3192 POU5F1 5460 pp -- int.I2D: BioGrid_Mouse, IntAct_Mouse
SCD 6319 INVS 27130 pd < reg.ITFP.txt: no annot
POU5F1 5460 SRSF3 6428 pp -- int.I2D: BioGrid
NUP160 23279 FBXO22 26263 pd < reg.ITFP.txt: no annot
DDIT3 1649 VARS 7407 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
NFIA 4774 NFIB 4781 pd <> reg.ITFP.txt: no annot
NCBP1 4686 INVS 27130 pd < reg.ITFP.txt: no annot
AGPS 8540 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
MED13L 23389 MED28 80306 pp -- int.I2D: BioGrid
HNRNPD 3184 HNRNPU 3192 pp -- int.Mint: MI:0915(physical association)
ETF1 2107 EIF2S2 8894 pp -- int.I2D: BioGrid_Yeast, YeastLow
NFIA 4774 NUDT21 11051 pd > reg.ITFP.txt: no annot
YAP1 10413 MED28 80306 pp -- int.I2D: MINT;
int.Mint: MI:0915(physical association)
HNRNPU 3192 PRPF40A 55660 pd < reg.ITFP.txt: no annot
HNRNPU 3192 PRPF40A 55660 pp -- int.I2D: BioGrid, Pawson1
EIF2S1 1965 EIF2S2 8894 pp -- int.Intact: MI:0407(direct interaction);
int.I2D: BCI, BioGrid_Yeast, IntAct, IntAct_Yeast, MINT_Yeast, YeastHigh, Yu_GoldStd, HPRD;
int.HPRD: in vitro
EPRS 2058 NCBP1 4686 pd > reg.ITFP.txt: no annot
EPRS 2058 SYNCRIP 10492 pd <> reg.ITFP.txt: no annot
EPRS 2058 SYNCRIP 10492 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, HPRD;
int.HPRD: in vivo
SRSF3 6428 ULK2 9706 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
SYNCRIP 10492 CPSF3 51692 pd > reg.ITFP.txt: no annot
MATR3 9782 NUDT21 11051 pd > reg.ITFP.txt: no annot
NFIA 4774 MED13L 23389 pd > reg.ITFP.txt: no annot
SYNCRIP 10492 NUDT21 11051 pd > reg.ITFP.txt: no annot
NFIB 4781 AGPS 8540 pd > reg.ITFP.txt: no annot
FBXO22 26263 INVS 27130 pd <> reg.ITFP.txt: no annot
TPR 7175 NUDT21 11051 pd > reg.ITFP.txt: no annot
NUDT21 11051 CBLL1 79872 pd < reg.ITFP.txt: no annot
EPRS 2058 SCD 6319 pd > reg.ITFP.txt: no annot
FBXO22 26263 CENPQ 55166 pd > reg.ITFP.txt: no annot
NCBP1 4686 PRPF40A 55660 pp -- int.I2D: INTEROLOG
HNRNPD 3184 SYNCRIP 10492 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vivo
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
HNRNPU 3192 SYNCRIP 10492 pp -- int.Mint: MI:0915(physical association)
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
APC 324 SYNCRIP 10492 pp -- int.I2D: Jorgensen_EphR
EIF2S1 1965 NUDT21 11051 pd > reg.ITFP.txt: no annot
ADA 100 NFIA 4774 pd < reg.pazar.txt: no annot
APC 324 MATR3 9782 pp -- int.I2D: Jorgensen_EphR
DDIT3 1649 HNRNPD 3184 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
SYNCRIP 10492 SYT8 90019 pp -- int.I2D: BioGrid, HPRD;
int.HPRD: in vitro, in vivo
NUDT21 11051 FBXO22 26263 pd < reg.ITFP.txt: no annot

Related GO terms (479)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0010467gene expression2.88e-084.70e-042.9081227669
GO:0008380RNA splicing6.22e-081.01e-033.851814232
GO:0005654nucleoplasm1.06e-071.74e-032.42014311095
GO:0000398mRNA splicing, via spliceosome1.11e-071.82e-034.15079165
GO:0003723RNA binding1.17e-071.92e-033.407915355
GO:0030529ribonucleoprotein complex2.75e-074.49e-034.46166114
GO:0044822poly(A) RNA binding6.84e-071.12e-022.33513271078
GO:0031124mRNA 3'-end processing2.92e-064.76e-025.3174442
GO:0006369termination of RNA polymerase II transcription3.86e-066.31e-025.2174445
GO:0006406mRNA export from nucleus1.41e-052.29e-014.7554562
GO:0005515protein binding1.45e-052.36e-010.93528776127
GO:0005850eukaryotic translation initiation factor 2 complex1.67e-052.72e-018.124223
GO:0005829cytosol3.18e-055.20e-011.47317382562
GO:0097452GAIT complex3.33e-055.43e-017.709224
GO:0070934CRD-mediated mRNA stabilization5.54e-059.04e-017.387225
GO:0006366transcription from RNA polymerase II promoter5.78e-059.43e-012.785714425
GO:0070937CRD-mediated mRNA stability complex8.30e-051.00e+007.124226
GO:0006379mRNA cleavage2.47e-041.00e+006.3872210
GO:0006396RNA processing3.93e-041.00e+004.3873460
GO:0042789mRNA transcription from RNA polymerase II promoter4.27e-041.00e+006.0092213
GO:0000776kinetochore4.54e-041.00e+004.3173463
GO:0005487nucleocytoplasmic transporter activity4.97e-041.00e+005.9022214
GO:0016020membrane5.36e-041.00e+001.52412271746
GO:0044212transcription regulatory region DNA binding7.19e-041.00e+003.29145171
GO:0090090negative regulation of canonical Wnt signaling pathway1.20e-031.00e+003.8353488
GO:0006378mRNA polyadenylation1.25e-031.00e+005.2502222
GO:0071346cellular response to interferon-gamma1.36e-031.00e+005.1852223
GO:0001649osteoblast differentiation1.50e-031.00e+003.7243395
GO:0043022ribosome binding2.02e-031.00e+004.9022228
GO:1901673regulation of spindle assembly involved in mitosis2.39e-031.00e+008.709111
GO:0043578nuclear matrix organization2.39e-031.00e+008.709111
GO:2000016negative regulation of determination of dorsal identity2.39e-031.00e+008.709111
GO:2000795negative regulation of epithelial cell proliferation involved in lung morphogenesis2.39e-031.00e+008.709111
GO:0010965regulation of mitotic sister chromatid separation2.39e-031.00e+008.709111
GO:0008609alkylglycerone-phosphate synthase activity2.39e-031.00e+008.709111
GO:0006404RNA import into nucleus2.39e-031.00e+008.709111
GO:0090308regulation of methylation-dependent chromatin silencing2.39e-031.00e+008.709111
GO:0006157deoxyadenosine catabolic process2.39e-031.00e+008.709111
GO:0090081regulation of heart induction by regulation of canonical Wnt signaling pathway2.39e-031.00e+008.709111
GO:0046111xanthine biosynthetic process2.39e-031.00e+008.709111
GO:0032261purine nucleotide salvage2.39e-031.00e+008.709111
GO:0042483negative regulation of odontogenesis2.39e-031.00e+008.709111
GO:0060169negative regulation of adenosine receptor signaling pathway2.39e-031.00e+008.709111
GO:0060795cell fate commitment involved in formation of primary germ layer2.39e-031.00e+008.709111
GO:0051171regulation of nitrogen compound metabolic process2.39e-031.00e+008.709111
GO:0021740principal sensory nucleus of trigeminal nerve development2.39e-031.00e+008.709111
GO:0008079translation termination factor activity2.39e-031.00e+008.709111
GO:0060407negative regulation of penile erection2.39e-031.00e+008.709111
GO:0031453positive regulation of heterochromatin assembly2.39e-031.00e+008.709111
GO:0061141lung ciliated cell differentiation2.39e-031.00e+008.709111
GO:0010827regulation of glucose transport2.48e-031.00e+004.7552331
GO:0007094mitotic spindle assembly checkpoint2.48e-031.00e+004.7552331
GO:0042594response to starvation2.64e-031.00e+004.7092332
GO:0016592mediator complex3.15e-031.00e+004.5802535
GO:0006260DNA replication3.28e-031.00e+003.32834125
GO:0007077mitotic nuclear envelope disassembly3.51e-031.00e+004.5002337
GO:0005634nucleus3.59e-031.00e+000.79420554828
GO:0000166nucleotide binding3.92e-031.00e+002.62246272
GO:0035019somatic stem cell maintenance4.10e-031.00e+004.3872240
GO:0017148negative regulation of translation4.30e-031.00e+004.3512341
GO:0006418tRNA aminoacylation for protein translation4.51e-031.00e+004.3172342
GO:0008645hexose transport4.51e-031.00e+004.3172342
GO:0004832valine-tRNA ligase activity4.77e-031.00e+007.709112
GO:0002314germinal center B cell differentiation4.77e-031.00e+007.709112
GO:0060242contact inhibition4.77e-031.00e+007.709112
GO:0031990mRNA export from nucleus in response to heat stress4.77e-031.00e+007.709112
GO:0044337canonical Wnt signaling pathway involved in positive regulation of apoptotic process4.77e-031.00e+007.709112
GO:0004818glutamate-tRNA ligase activity4.77e-031.00e+007.709112
GO:0006154adenosine catabolic process4.77e-031.00e+007.709112
GO:0005846nuclear cap binding complex4.77e-031.00e+007.709112
GO:0002176male germ cell proliferation4.77e-031.00e+007.709112
GO:0006438valyl-tRNA aminoacylation4.77e-031.00e+007.709112
GO:0009786regulation of asymmetric cell division4.77e-031.00e+007.709112
GO:0070840dynein complex binding4.77e-031.00e+007.709112
GO:0046103inosine biosynthetic process4.77e-031.00e+007.709112
GO:0060965negative regulation of gene silencing by miRNA4.77e-031.00e+007.709112
GO:0046832negative regulation of RNA export from nucleus4.77e-031.00e+007.709112
GO:1990440positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress4.77e-031.00e+007.709112
GO:0001883purine nucleoside binding4.77e-031.00e+007.709112
GO:0006424glutamyl-tRNA aminoacylation4.77e-031.00e+007.709112
GO:0000189MAPK import into nucleus4.77e-031.00e+007.709112
GO:0043558regulation of translational initiation in response to stress4.77e-031.00e+007.709112
GO:0006433prolyl-tRNA aminoacylation4.77e-031.00e+007.709112
GO:0004827proline-tRNA ligase activity4.77e-031.00e+007.709112
GO:2000791negative regulation of mesenchymal cell proliferation involved in lung development4.77e-031.00e+007.709112
GO:0009798axis specification4.77e-031.00e+007.709112
GO:0070256negative regulation of mucus secretion4.77e-031.00e+007.709112
GO:0044324regulation of transcription involved in anterior/posterior axis specification4.77e-031.00e+007.709112
GO:0042323negative regulation of circadian sleep/wake cycle, non-REM sleep4.77e-031.00e+007.709112
GO:0003743translation initiation factor activity6.10e-031.00e+004.0942549
GO:0044267cellular protein metabolic process6.18e-031.00e+002.08057495
GO:0006974cellular response to DNA damage stimulus6.30e-031.00e+002.99034158
GO:0043103hypoxanthine salvage7.15e-031.00e+007.124113
GO:0042306regulation of protein import into nucleus7.15e-031.00e+007.124113
GO:0006563L-serine metabolic process7.15e-031.00e+007.124113
GO:0016149translation release factor activity, codon specific7.15e-031.00e+007.124113
GO:0033632regulation of cell-cell adhesion mediated by integrin7.15e-031.00e+007.124113
GO:0046061dATP catabolic process7.15e-031.00e+007.124113
GO:0004768stearoyl-CoA 9-desaturase activity7.15e-031.00e+007.124113
GO:0006405RNA export from nucleus7.15e-031.00e+007.124113
GO:0003130BMP signaling pathway involved in heart induction7.15e-031.00e+007.124113
GO:0060205cytoplasmic membrane-bounded vesicle lumen7.15e-031.00e+007.124113
GO:0015758glucose transport8.74e-031.00e+003.8262359
GO:0005643nuclear pore8.74e-031.00e+003.8262359
GO:0034273ATG1/UKL1 signaling complex9.52e-031.00e+006.709114
GO:0060913cardiac cell fate determination9.52e-031.00e+006.709114
GO:0060486Clara cell differentiation9.52e-031.00e+006.709114
GO:0008611ether lipid biosynthetic process9.52e-031.00e+006.709114
GO:0035613RNA stem-loop binding9.52e-031.00e+006.709114
GO:0051151negative regulation of smooth muscle cell differentiation9.52e-031.00e+006.709114
GO:0097167circadian regulation of translation9.52e-031.00e+006.709114
GO:0003747translation release factor activity9.52e-031.00e+006.709124
GO:0002636positive regulation of germinal center formation9.52e-031.00e+006.709114
GO:0006290pyrimidine dimer repair9.52e-031.00e+006.709114
GO:0004647phosphoserine phosphatase activity9.52e-031.00e+006.709114
GO:0002906negative regulation of mature B cell apoptotic process9.52e-031.00e+006.709114
GO:0006999nuclear pore organization9.52e-031.00e+006.709114
GO:0006564L-serine biosynthetic process9.52e-031.00e+006.709114
GO:0044615nuclear pore nuclear basket9.52e-031.00e+006.709114
GO:0019887protein kinase regulator activity9.52e-031.00e+006.709114
GO:0001821histamine secretion9.52e-031.00e+006.709114
GO:0006987activation of signaling protein activity involved in unfolded protein response9.61e-031.00e+003.7552262
GO:0001714endodermal cell fate specification1.19e-021.00e+006.387115
GO:0044336canonical Wnt signaling pathway involved in negative regulation of apoptotic process1.19e-021.00e+006.387115
GO:0043620regulation of DNA-templated transcription in response to stress1.19e-021.00e+006.387115
GO:0004000adenosine deaminase activity1.19e-021.00e+006.387115
GO:0005849mRNA cleavage factor complex1.19e-021.00e+006.387115
GO:0021960anterior commissure morphogenesis1.19e-021.00e+006.387115
GO:0060971embryonic heart tube left/right pattern formation1.19e-021.00e+006.387115
GO:0002686negative regulation of leukocyte migration1.19e-021.00e+006.387115
GO:0048742regulation of skeletal muscle fiber development1.19e-021.00e+006.387115
GO:0006398histone mRNA 3'-end processing1.19e-021.00e+006.387115
GO:0045292mRNA cis splicing, via spliceosome1.19e-021.00e+006.387115
GO:0031442positive regulation of mRNA 3'-end processing1.19e-021.00e+006.387115
GO:0006449regulation of translational termination1.19e-021.00e+006.387115
GO:0010793regulation of mRNA export from nucleus1.19e-021.00e+006.387115
GO:0048671negative regulation of collateral sprouting1.19e-021.00e+006.387115
GO:0070849response to epidermal growth factor1.19e-021.00e+006.387115
GO:0003729mRNA binding1.31e-021.00e+003.5192373
GO:0042826histone deacetylase binding1.35e-021.00e+003.5002274
GO:0008762UDP-N-acetylmuramate dehydrogenase activity1.43e-021.00e+006.124116
GO:0030858positive regulation of epithelial cell differentiation1.43e-021.00e+006.124116
GO:0050847progesterone receptor signaling pathway1.43e-021.00e+006.124116
GO:0090267positive regulation of mitotic cell cycle spindle assembly checkpoint1.43e-021.00e+006.124116
GO:0060509Type I pneumocyte differentiation1.43e-021.00e+006.124116
GO:2000323negative regulation of glucocorticoid receptor signaling pathway1.43e-021.00e+006.124116
GO:0044300cerebellar mossy fiber1.43e-021.00e+006.124116
GO:0005851eukaryotic translation initiation factor 2B complex1.43e-021.00e+006.124136
GO:0071679commissural neuron axon guidance1.43e-021.00e+006.124116
GO:0071204histone pre-mRNA 3'end processing complex1.43e-021.00e+006.124116
GO:0042382paraspeckles1.43e-021.00e+006.124126
GO:0006355regulation of transcription, DNA-templated1.45e-021.00e+001.4087131104
GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activity1.45e-021.00e+003.4422277
GO:0001822kidney development1.53e-021.00e+003.4052279
GO:0071013catalytic step 2 spliceosome1.53e-021.00e+003.4052379
GO:0005737cytoplasm1.59e-021.00e+000.75216433976
GO:0016071mRNA metabolic process1.60e-021.00e+002.49338223
GO:0030968endoplasmic reticulum unfolded protein response1.60e-021.00e+003.3692281
GO:0007091metaphase/anaphase transition of mitotic cell cycle1.66e-021.00e+005.902117
GO:0060770negative regulation of epithelial cell proliferation involved in prostate gland development1.66e-021.00e+005.902117
GO:0046825regulation of protein export from nucleus1.66e-021.00e+005.902127
GO:0051988regulation of attachment of spindle microtubules to kinetochore1.66e-021.00e+005.902117
GO:0002161aminoacyl-tRNA editing activity1.66e-021.00e+005.902117
GO:0004521endoribonuclease activity1.66e-021.00e+005.902117
GO:0050862positive regulation of T cell receptor signaling pathway1.66e-021.00e+005.902117
GO:0006301postreplication repair1.66e-021.00e+005.902117
GO:0060510Type II pneumocyte differentiation1.66e-021.00e+005.902117
GO:0006282regulation of DNA repair1.66e-021.00e+005.902117
GO:0006412translation1.84e-021.00e+002.41735235
GO:0045670regulation of osteoclast differentiation1.90e-021.00e+005.709118
GO:0051292nuclear pore complex assembly1.90e-021.00e+005.709118
GO:0001955blood vessel maturation1.90e-021.00e+005.709118
GO:0000339RNA cap binding1.90e-021.00e+005.709118
GO:0035457cellular response to interferon-alpha1.90e-021.00e+005.709118
GO:0070244negative regulation of thymocyte apoptotic process1.90e-021.00e+005.709118
GO:0033089positive regulation of T cell differentiation in thymus1.90e-021.00e+005.709118
GO:0016363nuclear matrix2.03e-021.00e+003.1852592
GO:0008134transcription factor binding2.07e-021.00e+002.35136246
GO:0016070RNA metabolic process2.10e-021.00e+002.34638247
GO:0042405nuclear inclusion body2.13e-021.00e+005.539119
GO:0071354cellular response to interleukin-62.13e-021.00e+005.539119
GO:00084095'-3' exonuclease activity2.13e-021.00e+005.539119
GO:0033197response to vitamin E2.13e-021.00e+005.539119
GO:0010388cullin deneddylation2.13e-021.00e+005.539159
GO:0005847mRNA cleavage and polyadenylation specificity factor complex2.13e-021.00e+005.539119
GO:0046638positive regulation of alpha-beta T cell differentiation2.13e-021.00e+005.539119
GO:0006983ER overload response2.13e-021.00e+005.539119
GO:0043495protein anchor2.13e-021.00e+005.539119
GO:0048541Peyer's patch development2.13e-021.00e+005.539119
GO:0005832chaperonin-containing T-complex2.13e-021.00e+005.539119
GO:0008610lipid biosynthetic process2.36e-021.00e+005.3871110
GO:0002199zona pellucida receptor complex2.36e-021.00e+005.3871110
GO:0045667regulation of osteoblast differentiation2.36e-021.00e+005.3871110
GO:0031274positive regulation of pseudopodium assembly2.36e-021.00e+005.3871110
GO:0006450regulation of translational fidelity2.36e-021.00e+005.3871110
GO:0071949FAD binding2.36e-021.00e+005.3871110
GO:0043101purine-containing compound salvage2.36e-021.00e+005.3871110
GO:0031080nuclear pore outer ring2.36e-021.00e+005.3871110
GO:0010225response to UV-C2.36e-021.00e+005.3871210
GO:0000731DNA synthesis involved in DNA repair2.36e-021.00e+005.3871110
GO:0010944negative regulation of transcription by competitive promoter binding2.36e-021.00e+005.3871110
GO:0030877beta-catenin destruction complex2.36e-021.00e+005.3871110
GO:0005845mRNA cap binding complex2.60e-021.00e+005.2501111
GO:0051010microtubule plus-end binding2.60e-021.00e+005.2501211
GO:0007340acrosome reaction2.60e-021.00e+005.2501111
GO:0045662negative regulation of myoblast differentiation2.60e-021.00e+005.2501111
GO:0031116positive regulation of microtubule polymerization2.60e-021.00e+005.2501111
GO:0035413positive regulation of catenin import into nucleus2.60e-021.00e+005.2501111
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process2.60e-021.00e+005.2501111
GO:0042162telomeric DNA binding2.60e-021.00e+005.2501111
GO:0060391positive regulation of SMAD protein import into nucleus2.60e-021.00e+005.2501111
GO:0009168purine ribonucleoside monophosphate biosynthetic process2.83e-021.00e+005.1241212
GO:0032886regulation of microtubule-based process2.83e-021.00e+005.1241112
GO:0045947negative regulation of translational initiation2.83e-021.00e+005.1241112
GO:0008334histone mRNA metabolic process2.83e-021.00e+005.1241112
GO:0045295gamma-catenin binding2.83e-021.00e+005.1241112
GO:0019079viral genome replication2.83e-021.00e+005.1241112
GO:0034045pre-autophagosomal structure membrane2.83e-021.00e+005.1241112
GO:0008143poly(A) binding2.83e-021.00e+005.1241212
GO:0034399nuclear periphery2.83e-021.00e+005.1241112
GO:0006461protein complex assembly2.88e-021.00e+002.91522111
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay3.03e-021.00e+002.87623114
GO:0043488regulation of mRNA stability3.06e-021.00e+005.0091113
GO:0010001glial cell differentiation3.06e-021.00e+005.0091113
GO:0060766negative regulation of androgen receptor signaling pathway3.06e-021.00e+005.0091113
GO:0010460positive regulation of heart rate3.06e-021.00e+005.0091113
GO:0044295axonal growth cone3.06e-021.00e+005.0091113
GO:0051019mitogen-activated protein kinase binding3.06e-021.00e+005.0091213
GO:0043409negative regulation of MAPK cascade3.06e-021.00e+005.0091213
GO:0005868cytoplasmic dynein complex3.06e-021.00e+005.0091113
GO:0035198miRNA binding3.06e-021.00e+005.0091113
GO:0046827positive regulation of protein export from nucleus3.06e-021.00e+005.0091113
GO:0005635nuclear envelope3.13e-021.00e+002.85123116
GO:0035371microtubule plus-end3.30e-021.00e+004.9021114
GO:0071480cellular response to gamma radiation3.30e-021.00e+004.9021114
GO:0048566embryonic digestive tract development3.30e-021.00e+004.9021114
GO:0005095GTPase inhibitor activity3.30e-021.00e+004.9021114
GO:0045807positive regulation of endocytosis3.30e-021.00e+004.9021114
GO:0032465regulation of cytokinesis3.30e-021.00e+004.9021114
GO:0042307positive regulation of protein import into nucleus3.53e-021.00e+004.8021215
GO:0017091AU-rich element binding3.53e-021.00e+004.8021215
GO:0006479protein methylation3.53e-021.00e+004.8021215
GO:0001824blastocyst development3.53e-021.00e+004.8021115
GO:0006401RNA catabolic process3.53e-021.00e+004.8021115
GO:0045987positive regulation of smooth muscle contraction3.53e-021.00e+004.8021115
GO:0007050cell cycle arrest3.64e-021.00e+002.73223126
GO:0032839dendrite cytoplasm3.76e-021.00e+004.7091116
GO:0007026negative regulation of microtubule depolymerization3.76e-021.00e+004.7091216
GO:0030902hindbrain development3.76e-021.00e+004.7091116
GO:0046716muscle cell cellular homeostasis3.76e-021.00e+004.7091116
GO:0051276chromosome organization3.76e-021.00e+004.7091216
GO:0030335positive regulation of cell migration3.85e-021.00e+002.68722130
GO:0006413translational initiation3.90e-021.00e+002.67624131
GO:0016477cell migration3.90e-021.00e+002.67622131
GO:0016032viral process3.91e-021.00e+001.632416540
GO:0001829trophectodermal cell differentiation3.99e-021.00e+004.6221217
GO:0043274phospholipase binding3.99e-021.00e+004.6221117
GO:0008652cellular amino acid biosynthetic process3.99e-021.00e+004.6221117
GO:0070064proline-rich region binding4.22e-021.00e+004.5391118
GO:0031122cytoplasmic microtubule organization4.22e-021.00e+004.5391118
GO:0090316positive regulation of intracellular protein transport4.22e-021.00e+004.5391118
GO:0045736negative regulation of cyclin-dependent protein serine/threonine kinase activity4.45e-021.00e+004.4611219
GO:0031667response to nutrient levels4.45e-021.00e+004.4611119
GO:0016055Wnt signaling pathway4.46e-021.00e+002.56923141
GO:0050850positive regulation of calcium-mediated signaling4.67e-021.00e+004.3871120
GO:0005215transporter activity4.69e-021.00e+002.52922145
GO:0048675axon extension4.90e-021.00e+004.3171121
GO:0032757positive regulation of interleukin-8 production4.90e-021.00e+004.3171121
GO:0009954proximal/distal pattern formation4.90e-021.00e+004.3171121
GO:0043278response to morphine4.90e-021.00e+004.3171121
GO:0016575histone deacetylation4.90e-021.00e+004.3171121
GO:0000281mitotic cytokinesis4.90e-021.00e+004.3171121
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription5.04e-021.00e+002.47122151
GO:0001106RNA polymerase II transcription corepressor activity5.13e-021.00e+004.2501122
GO:0033574response to testosterone5.13e-021.00e+004.2501122
GO:0036464cytoplasmic ribonucleoprotein granule5.13e-021.00e+004.2501122
GO:0031016pancreas development5.13e-021.00e+004.2501122
GO:0010506regulation of autophagy5.36e-021.00e+004.1851123
GO:0034660ncRNA metabolic process5.36e-021.00e+004.1851123
GO:0046777protein autophosphorylation5.47e-021.00e+002.40523158
GO:0008135translation factor activity, nucleic acid binding5.58e-021.00e+004.1241224
GO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress5.58e-021.00e+004.1241124
GO:0006611protein export from nucleus5.81e-021.00e+004.0651125
GO:0030864cortical actin cytoskeleton5.81e-021.00e+004.0651125
GO:0005844polysome5.81e-021.00e+004.0651225
GO:0045296cadherin binding5.81e-021.00e+004.0651125
GO:0035329hippo signaling6.04e-021.00e+004.0091126
GO:0031047gene silencing by RNA6.04e-021.00e+004.0091226
GO:0000045autophagic vacuole assembly6.04e-021.00e+004.0091126
GO:0051209release of sequestered calcium ion into cytosol6.04e-021.00e+004.0091226
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding6.09e-021.00e+002.31723168
GO:0006397mRNA processing6.15e-021.00e+002.30826169
GO:0006913nucleocytoplasmic transport6.26e-021.00e+003.9541127
GO:0000188inactivation of MAPK activity6.26e-021.00e+003.9541127
GO:0043392negative regulation of DNA binding6.26e-021.00e+003.9541127
GO:0034080CENP-A containing nucleosome assembly6.26e-021.00e+003.9541227
GO:0000387spliceosomal snRNP assembly6.26e-021.00e+003.9541127
GO:0007339binding of sperm to zona pellucida6.26e-021.00e+003.9541127
GO:0005637nuclear inner membrane6.48e-021.00e+003.9021128
GO:0016607nuclear speck6.54e-021.00e+002.25826175
GO:0007049cell cycle6.67e-021.00e+002.24124177
GO:0015631tubulin binding6.71e-021.00e+003.8511129
GO:0005913cell-cell adherens junction6.71e-021.00e+003.8511129
GO:0003887DNA-directed DNA polymerase activity6.71e-021.00e+003.8511129
GO:0034605cellular response to heat6.71e-021.00e+003.8511129
GO:0072686mitotic spindle6.71e-021.00e+003.8511129
GO:0071897DNA biosynthetic process6.71e-021.00e+003.8511129
GO:0003714transcription corepressor activity6.81e-021.00e+002.22525179
GO:0000278mitotic cell cycle6.90e-021.00e+001.657312398
GO:0006606protein import into nucleus6.93e-021.00e+003.8021130
GO:00063707-methylguanosine mRNA capping6.93e-021.00e+003.8021230
GO:0031647regulation of protein stability6.93e-021.00e+003.8021230
GO:0051262protein tetramerization6.93e-021.00e+003.8021130
GO:0010494cytoplasmic stress granule6.93e-021.00e+003.8021230
GO:0005782peroxisomal matrix7.15e-021.00e+003.7551131
GO:0009953dorsal/ventral pattern formation7.38e-021.00e+003.7091132
GO:0006144purine nucleobase metabolic process7.38e-021.00e+003.7091232
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic7.38e-021.00e+003.7091132
GO:0002062chondrocyte differentiation7.38e-021.00e+003.7091232
GO:1903507negative regulation of nucleic acid-templated transcription7.38e-021.00e+003.7091132
GO:0033077T cell differentiation in thymus7.60e-021.00e+003.6651133
GO:0007162negative regulation of cell adhesion7.60e-021.00e+003.6651133
GO:0031072heat shock protein binding7.60e-021.00e+003.6651133
GO:0001104RNA polymerase II transcription cofactor activity7.60e-021.00e+003.6651333
GO:0070830tight junction assembly7.60e-021.00e+003.6651133
GO:0008180COP9 signalosome7.82e-021.00e+003.6221634
GO:0001890placenta development7.82e-021.00e+003.6221134
GO:0048286lung alveolus development7.82e-021.00e+003.6221134
GO:0001942hair follicle development8.04e-021.00e+003.5801135
GO:0030890positive regulation of B cell proliferation8.04e-021.00e+003.5801135
GO:0009267cellular response to starvation8.26e-021.00e+003.5391136
GO:0048538thymus development8.26e-021.00e+003.5391136
GO:0006446regulation of translational initiation8.26e-021.00e+003.5391236
GO:0051084'de novo' posttranslational protein folding8.48e-021.00e+003.5001137
GO:0042752regulation of circadian rhythm8.48e-021.00e+003.5001337
GO:0006633fatty acid biosynthetic process8.48e-021.00e+003.5001137
GO:0051781positive regulation of cell division8.92e-021.00e+003.4241139
GO:0042542response to hydrogen peroxide9.14e-021.00e+003.3871140
GO:0005881cytoplasmic microtubule9.35e-021.00e+003.3511241
GO:0045785positive regulation of cell adhesion9.35e-021.00e+003.3511141
GO:0042110T cell activation9.79e-021.00e+003.2831243
GO:0014070response to organic cyclic compound9.79e-021.00e+003.2831143
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process1.00e-011.00e+003.2501144
GO:0050434positive regulation of viral transcription1.00e-011.00e+003.2501244
GO:0005730nucleolus1.01e-011.00e+000.7997281684
GO:0005739mitochondrion1.02e-011.00e+001.0005161046
GO:0016328lateral plasma membrane1.04e-011.00e+003.1851146
GO:0019221cytokine-mediated signaling pathway1.04e-011.00e+001.86423230
GO:0044297cell body1.04e-011.00e+003.1851146
GO:0043525positive regulation of neuron apoptotic process1.04e-011.00e+003.1851246
GO:0019898extrinsic component of membrane1.04e-011.00e+003.1851146
GO:0045727positive regulation of translation1.04e-011.00e+003.1851246
GO:0006921cellular component disassembly involved in execution phase of apoptosis1.06e-011.00e+003.1541147
GO:0019827stem cell maintenance1.09e-011.00e+003.1241248
GO:0045893positive regulation of transcription, DNA-templated1.10e-011.00e+001.36636487
GO:0045111intermediate filament cytoskeleton1.11e-011.00e+003.0941149
GO:0005778peroxisomal membrane1.13e-011.00e+003.0651250
GO:0006986response to unfolded protein1.15e-011.00e+003.0371251
GO:0001669acrosomal vesicle1.15e-011.00e+003.0371151
GO:0007254JNK cascade1.15e-011.00e+003.0371251
GO:0003684damaged DNA binding1.15e-011.00e+003.0371151
GO:0045732positive regulation of protein catabolic process1.15e-011.00e+003.0371151
GO:0000775chromosome, centromeric region1.17e-011.00e+003.0091352
GO:0034976response to endoplasmic reticulum stress1.17e-011.00e+003.0091152
GO:0045454cell redox homeostasis1.17e-011.00e+003.0091152
GO:0009611response to wounding1.19e-011.00e+002.9811153
GO:0060041retina development in camera-type eye1.19e-011.00e+002.9811153
GO:0009612response to mechanical stimulus1.21e-011.00e+002.9541154
GO:0004842ubiquitin-protein transferase activity1.25e-011.00e+001.70925256
GO:0005874microtubule1.26e-011.00e+001.69823258
GO:0045944positive regulation of transcription from RNA polymerase II promoter1.27e-011.00e+001.045413811
GO:0048306calcium-dependent protein binding1.28e-011.00e+002.8761157
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity1.32e-011.00e+002.8261259
GO:0050728negative regulation of inflammatory response1.34e-011.00e+002.8021160
GO:0008013beta-catenin binding1.34e-011.00e+002.8021460
GO:0005975carbohydrate metabolic process1.39e-011.00e+001.61123274
GO:0000151ubiquitin ligase complex1.40e-011.00e+002.7321263
GO:0007409axonogenesis1.46e-011.00e+002.6651166
GO:0006368transcription elongation from RNA polymerase II promoter1.48e-011.00e+002.6431367
GO:0016787hydrolase activity1.54e-011.00e+002.5801170
GO:0032587ruffle membrane1.59e-011.00e+002.5391172
GO:0010468regulation of gene expression1.59e-011.00e+002.5391172
GO:0008021synaptic vesicle1.61e-011.00e+002.5191273
GO:0055086nucleobase-containing small molecule metabolic process1.61e-011.00e+002.5191273
GO:0009791post-embryonic development1.65e-011.00e+002.4801175
GO:0060070canonical Wnt signaling pathway1.65e-011.00e+002.4801275
GO:0000122negative regulation of transcription from RNA polymerase II promoter1.65e-011.00e+001.092310589
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process1.67e-011.00e+002.4611276
GO:0008584male gonad development1.69e-011.00e+002.4421177
GO:0006334nucleosome assembly1.73e-011.00e+002.4051379
GO:0051301cell division1.77e-011.00e+002.3691281
GO:0001889liver development1.79e-011.00e+002.3511282
GO:0042803protein homodimerization activity1.82e-011.00e+001.02536617
GO:0009952anterior/posterior pattern specification1.82e-011.00e+002.3171284
GO:0005929cilium1.82e-011.00e+002.3171184
GO:0009653anatomical structure morphogenesis1.88e-011.00e+002.2661187
GO:0006415translational termination1.88e-011.00e+002.2661287
GO:0006464cellular protein modification process1.92e-011.00e+002.2331189
GO:0005813centrosome1.94e-011.00e+001.30424339
GO:0044281small molecule metabolic process1.94e-011.00e+000.6925121295
GO:0005777peroxisome1.94e-011.00e+002.2171190
GO:0003690double-stranded DNA binding1.96e-011.00e+002.2011191
GO:0016337single organismal cell-cell adhesion1.98e-011.00e+002.1851192
GO:0005923tight junction1.98e-011.00e+002.1851192
GO:0005770late endosome2.02e-011.00e+002.1541194
GO:0016311dephosphorylation2.02e-011.00e+002.1541194
GO:0051082unfolded protein binding2.04e-011.00e+002.1391395
GO:0007010cytoskeleton organization2.06e-011.00e+002.1241196
GO:0030018Z disc2.10e-011.00e+002.0941298
GO:0043565sequence-specific DNA binding2.17e-011.00e+001.19723365
GO:0008285negative regulation of cell proliferation2.19e-011.00e+001.18924367
GO:0005524ATP binding2.19e-011.00e+000.6285131354
GO:0008360regulation of cell shape2.25e-011.00e+001.98111106
GO:0030659cytoplasmic vesicle membrane2.26e-011.00e+001.96811107
GO:0007155cell adhesion2.34e-011.00e+001.12422384
GO:0030308negative regulation of cell growth2.38e-011.00e+001.88912113
GO:0005819spindle2.39e-011.00e+001.87612114
GO:0000209protein polyubiquitination2.43e-011.00e+001.85115116
GO:0007568aging2.56e-011.00e+001.76712123
GO:0005506iron ion binding2.63e-011.00e+001.72011127
GO:0006511ubiquitin-dependent protein catabolic process2.63e-011.00e+001.72013127
GO:0003700sequence-specific DNA binding transcription factor activity2.65e-011.00e+000.747310748
GO:0009986cell surface2.67e-011.00e+000.98824422
GO:0030027lamellipodium2.68e-011.00e+001.68711130
GO:0045892negative regulation of transcription, DNA-templated2.69e-011.00e+000.98127424
GO:0044255cellular lipid metabolic process2.86e-011.00e+001.58011140
GO:0006457protein folding3.01e-011.00e+001.49011149
GO:0008017microtubule binding3.03e-011.00e+001.48014150
GO:0001666response to hypoxia3.03e-011.00e+001.48013150
GO:0042981regulation of apoptotic process3.04e-011.00e+001.47113151
GO:0005198structural molecule activity3.18e-011.00e+001.39611159
GO:0055114oxidation-reduction process3.20e-011.00e+000.79922481
GO:0043005neuron projection3.21e-011.00e+001.37814161
GO:0005516calmodulin binding3.23e-011.00e+001.36911162
GO:0042802identical protein binding3.29e-011.00e+000.76926491
GO:0000287magnesium ion binding3.42e-011.00e+001.26612174
GO:0031965nuclear membrane3.45e-011.00e+001.25011176
GO:0034641cellular nitrogen compound metabolic process3.47e-011.00e+001.24113177
GO:0005667transcription factor complex3.48e-011.00e+001.23313178
GO:0055085transmembrane transport3.49e-011.00e+000.70325514
GO:0031625ubiquitin protein ligase binding3.51e-011.00e+001.21712180
GO:0005764lysosome3.55e-011.00e+001.20111182
GO:0009897external side of plasma membrane3.56e-011.00e+001.19311183
GO:0006367transcription initiation from RNA polymerase II promoter3.58e-011.00e+001.18515184
GO:0001701in utero embryonic development3.97e-011.00e+000.99512210
GO:0003677DNA binding4.06e-011.00e+000.3094161351
GO:0016874ligase activity4.17e-011.00e+000.90214224
GO:0007067mitotic nuclear division4.27e-011.00e+000.85714231
GO:0005783endoplasmic reticulum4.31e-011.00e+000.45622610
GO:0003713transcription coactivator activity4.38e-011.00e+000.80817239
GO:0043025neuronal cell body4.58e-011.00e+000.72013254
GO:0006281DNA repair4.71e-011.00e+000.66514264
GO:0008270zinc ion binding4.74e-011.00e+000.2353111067
GO:0043065positive regulation of apoptotic process4.84e-011.00e+000.61113274
GO:0003779actin binding4.85e-011.00e+000.60611275
GO:0006357regulation of transcription from RNA polymerase II promoter4.85e-011.00e+000.60614275
GO:0042493response to drug5.01e-011.00e+000.53911288
GO:0019899enzyme binding5.01e-011.00e+000.53913288
GO:0016567protein ubiquitination5.14e-011.00e+000.48515299
GO:0005743mitochondrial inner membrane5.15e-011.00e+000.48013300
GO:0004674protein serine/threonine kinase activity5.29e-011.00e+000.42412312
GO:0019901protein kinase binding5.38e-011.00e+000.38714320
GO:0008283cell proliferation5.51e-011.00e+000.33813331
GO:0043231intracellular membrane-bounded organelle5.52e-011.00e+000.33411332
GO:0003682chromatin binding5.54e-011.00e+000.32517334
GO:0030054cell junction5.77e-011.00e+000.23313356
GO:0015031protein transport5.78e-011.00e+000.22912357
GO:0046982protein heterodimerization activity6.20e-011.00e+000.06913399
GO:0007165signal transduction6.71e-011.00e+00-0.18328950
GO:0046872metal ion binding6.93e-011.00e+00-0.223361465
GO:0006351transcription, DNA-templated7.44e-011.00e+00-0.3363171585
GO:0006915apoptotic process7.51e-011.00e+00-0.44818571
GO:0005509calcium ion binding7.62e-011.00e+00-0.49311589
GO:0005789endoplasmic reticulum membrane7.88e-011.00e+00-0.60412636
GO:0070062extracellular vesicular exosome8.72e-011.00e+00-0.5884152516
GO:0005887integral component of plasma membrane9.06e-011.00e+00-1.19911961
GO:0005615extracellular space9.17e-011.00e+00-1.271141010
GO:0005886plasma membrane9.26e-011.00e+00-0.7604142834
GO:0016021integral component of membrane9.87e-011.00e+00-1.569272483