Subnetwork | Dataset | Score | p-value 1 | p-value 2 | p-value 3 | Size | Highlighted genes |
---|---|---|---|---|---|---|---|
reg-snw-3145 | chia-screen-data-Fav | 2.226 | 2.10e-07 | 3.98e-02 | 3.04e-02 | 23 | 17 |
int-snw-10980 | chia-screen-data-Fav | 2.797 | 4.21e-15 | 7.56e-04 | 4.65e-03 | 12 | 8 |
Gene Symbol | Entrez Gene ID | Frequency | chia-screen-data-Fav gene score | Best subnetwork score | Degree | Chia-Hits Primary | Chia-Hits Secondary |
---|---|---|---|---|---|---|---|
NDUFA4L2 | 56901 | 10 | -2.477 | 2.459 | 21 | Yes | - |
EP300 | 2033 | 2 | -2.274 | 3.120 | 415 | Yes | Yes |
ANAPC5 | 51433 | 6 | -1.264 | 2.263 | 239 | - | - |
CENPA | 1058 | 5 | -2.185 | 2.393 | 205 | Yes | - |
COPS2 | 9318 | 2 | -2.531 | 3.043 | 46 | Yes | - |
CNOT1 | 23019 | 7 | -2.347 | 2.263 | 124 | Yes | - |
PHB2 | 11331 | 6 | -2.236 | 2.994 | 151 | Yes | - |
PHB | 5245 | 12 | -2.743 | 2.689 | 163 | Yes | Yes |
REXO4 | 57109 | 3 | -1.743 | 2.287 | 95 | - | - |
MED13L | 23389 | 8 | -2.550 | 2.307 | 50 | Yes | - |
YAP1 | 10413 | 12 | -4.256 | 3.538 | 53 | Yes | - |
HMOX2 | 3163 | 2 | -2.116 | 2.797 | 36 | Yes | - |
POU5F1 | 5460 | 12 | -5.148 | 3.538 | 179 | Yes | Yes |
KLHL8 | 57563 | 2 | -1.993 | 2.797 | 35 | - | - |
FBXL6 | 26233 | 5 | -2.253 | 2.689 | 22 | Yes | - |
SUV39H2 | 79723 | 7 | -2.307 | 2.410 | 21 | Yes | Yes |
COPS4 | 51138 | 2 | -3.198 | 3.043 | 62 | Yes | Yes |
SNAP23 | 8773 | 3 | -2.073 | 2.430 | 15 | Yes | - |
COPS3 | 8533 | 5 | -1.873 | 2.435 | 118 | - | - |
POLR2E | 5434 | 5 | -2.037 | 2.644 | 316 | Yes | - |
NOD2 | 64127 | 2 | -1.921 | 2.797 | 26 | - | - |
HMBS | 3145 | 3 | -1.117 | 2.226 | 22 | - | - |
CLPP | 8192 | 3 | -2.200 | 2.291 | 10 | Yes | - |
CCT7 | 10574 | 10 | -2.335 | 2.459 | 173 | Yes | - |
HNRNPU | 3192 | 12 | -2.869 | 2.644 | 172 | Yes | - |
EIF2B3 | 8891 | 5 | -2.546 | 2.435 | 13 | Yes | Yes |
COPS6 | 10980 | 3 | -1.765 | 2.393 | 157 | - | - |
GPS1 | 2873 | 10 | -3.621 | 2.689 | 62 | Yes | Yes |
ZNRD1 | 30834 | 3 | -1.375 | 2.226 | 106 | - | - |
FUBP1 | 8880 | 6 | -2.414 | 2.389 | 41 | Yes | Yes |
TMEM14B | 81853 | 3 | -2.879 | 2.226 | 6 | Yes | Yes |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
CENPA | 1058 | ZNRD1 | 30834 | pd | <> | reg.ITFP.txt: no annot |
CCT7 | 10574 | REXO4 | 57109 | pd | < | reg.ITFP.txt: no annot |
CCT7 | 10574 | ZNRD1 | 30834 | pd | < | reg.ITFP.txt: no annot |
EP300 | 2033 | COPS6 | 10980 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid, HPRD, IntAct, StelzlMedium; int.HPRD: yeast 2-hybrid |
GPS1 | 2873 | PHB | 5245 | pd | > | reg.ITFP.txt: no annot |
POLR2E | 5434 | ANAPC5 | 51433 | pd | <> | reg.ITFP.txt: no annot |
COPS6 | 10980 | KLHL8 | 57563 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid, IntAct |
HNRNPU | 3192 | ANAPC5 | 51433 | pd | < | reg.ITFP.txt: no annot |
COPS3 | 8533 | COPS6 | 10980 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid, BIND, HPRD, IntAct, BCI, INNATEDB, MGI; int.HPRD: in vitro; int.DIP: MI:0915(physical association) |
COPS6 | 10980 | COPS4 | 51138 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid, BioGrid_Fly, BIND_Fly, FlyLow, HPRD, IntAct, IntAct_Fly, BIND, MGI, MINT_Fly; int.HPRD: in vitro |
CNOT1 | 23019 | ANAPC5 | 51433 | pd | < | reg.ITFP.txt: no annot |
COPS3 | 8533 | COPS2 | 9318 | pp | -- | int.I2D: BioGrid, BCI, HPRD, INNATEDB, MGI; int.HPRD: in vitro; int.DIP: MI:0915(physical association) |
HMOX2 | 3163 | COPS6 | 10980 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid, HPRD, MINT, StelzlMedium, IntAct; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid |
GPS1 | 2873 | COPS6 | 10980 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, BioGrid, HPRD, MGI; int.HPRD: in vitro |
HMBS | 3145 | COPS3 | 8533 | pd | < | reg.ITFP.txt: no annot |
GPS1 | 2873 | COPS4 | 51138 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BIND, IntAct, MGI |
CENPA | 1058 | SUV39H2 | 79723 | pd | > | reg.ITFP.txt: no annot |
POLR2E | 5434 | SNAP23 | 8773 | pd | > | reg.ITFP.txt: no annot |
PHB | 5245 | PHB2 | 11331 | pp | -- | int.I2D: BioGrid, BioGrid_Yeast, IntAct_Yeast |
CENPA | 1058 | FBXL6 | 26233 | pd | > | reg.ITFP.txt: no annot |
HMBS | 3145 | REXO4 | 57109 | pd | < | reg.ITFP.txt: no annot |
HMBS | 3145 | ZNRD1 | 30834 | pd | < | reg.ITFP.txt: no annot |
CENPA | 1058 | HMBS | 3145 | pd | > | reg.ITFP.txt: no annot |
HMBS | 3145 | ANAPC5 | 51433 | pd | < | reg.ITFP.txt: no annot |
PHB2 | 11331 | ZNRD1 | 30834 | pd | < | reg.ITFP.txt: no annot |
HNRNPU | 3192 | YAP1 | 10413 | pp | -- | int.I2D: HPRD; int.HPRD: in vitro, in vivo |
HNRNPU | 3192 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
GPS1 | 2873 | COPS2 | 9318 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Worm, MGI, MINT_Worm, BioGrid_Worm, BIND, BIND_Worm, CORE_1, HPRD, IntAct, INNATEDB; int.HPRD: in vitro, yeast 2-hybrid |
GPS1 | 2873 | CLPP | 8192 | pd | > | reg.ITFP.txt: no annot |
COPS2 | 9318 | COPS4 | 51138 | pp | -- | int.I2D: BIND, HPRD, MGI; int.HPRD: in vitro, in vivo |
COPS6 | 10980 | NOD2 | 64127 | pp | -- | int.I2D: INNATEDB |
GPS1 | 2873 | COPS3 | 8533 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: HPRD, IntAct, INNATEDB, BioGrid, MGI; int.HPRD: in vitro, yeast 2-hybrid |
ZNRD1 | 30834 | TMEM14B | 81853 | pd | > | reg.ITFP.txt: no annot |
PHB | 5245 | ZNRD1 | 30834 | pd | < | reg.ITFP.txt: no annot |
COPS3 | 8533 | EIF2B3 | 8891 | pd | > | reg.ITFP.txt: no annot |
HMBS | 3145 | COPS6 | 10980 | pd | < | reg.ITFP.txt: no annot |
EP300 | 2033 | YAP1 | 10413 | pp | -- | int.I2D: BioGrid |
MED13L | 23389 | ANAPC5 | 51433 | pd | < | reg.ITFP.txt: no annot |
CENPA | 1058 | NDUFA4L2 | 56901 | pd | > | reg.ITFP.txt: no annot |
EP300 | 2033 | HNRNPU | 3192 | pp | -- | int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vitro, in vivo |
GPS1 | 2873 | PHB2 | 11331 | pd | > | reg.ITFP.txt: no annot |
SNAP23 | 8773 | ANAPC5 | 51433 | pd | < | reg.ITFP.txt: no annot |
EP300 | 2033 | ANAPC5 | 51433 | pp | -- | int.I2D: BioGrid |
HNRNPU | 3192 | POLR2E | 5434 | pd | < | reg.ITFP.txt: no annot |
COPS2 | 9318 | COPS6 | 10980 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BCI, BIND, BioGrid, HPRD, IntAct, MGI; int.HPRD: in vitro |
FUBP1 | 8880 | ANAPC5 | 51433 | pd | <> | reg.ITFP.txt: no annot |
CLPP | 8192 | COPS6 | 10980 | pd | < | reg.ITFP.txt: no annot |
COPS3 | 8533 | COPS4 | 51138 | pp | -- | int.I2D: BIND, HPRD, BioGrid, INNATEDB, MGI; int.HPRD: in vitro, in vivo; int.DIP: MI:0915(physical association) |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0010388 | cullin deneddylation | 2.21e-12 | 3.60e-08 | 8.192 | 5 | 5 | 9 |
GO:0008180 | COP9 signalosome | 3.64e-11 | 5.94e-07 | 6.538 | 6 | 6 | 34 |
GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway | 1.56e-04 | 1.00e+00 | 6.718 | 2 | 2 | 10 |
GO:0005515 | protein binding | 1.62e-04 | 1.00e+00 | 0.919 | 22 | 77 | 6127 |
GO:0001054 | RNA polymerase I activity | 1.90e-04 | 1.00e+00 | 6.581 | 2 | 2 | 11 |
GO:0005736 | DNA-directed RNA polymerase I complex | 2.28e-04 | 1.00e+00 | 6.455 | 2 | 2 | 12 |
GO:0006778 | porphyrin-containing compound metabolic process | 5.24e-04 | 1.00e+00 | 5.870 | 2 | 2 | 18 |
GO:0005654 | nucleoplasm | 7.86e-04 | 1.00e+00 | 1.944 | 8 | 31 | 1095 |
GO:0006366 | transcription from RNA polymerase II promoter | 1.14e-03 | 1.00e+00 | 2.631 | 5 | 14 | 425 |
GO:0030331 | estrogen receptor binding | 1.19e-03 | 1.00e+00 | 5.285 | 2 | 2 | 27 |
GO:0002367 | cytokine production involved in immune response | 1.90e-03 | 1.00e+00 | 9.040 | 1 | 1 | 1 |
GO:1901985 | positive regulation of protein acetylation | 1.90e-03 | 1.00e+00 | 9.040 | 1 | 1 | 1 |
GO:0032498 | detection of muramyl dipeptide | 1.90e-03 | 1.00e+00 | 9.040 | 1 | 1 | 1 |
GO:0043969 | histone H2B acetylation | 1.90e-03 | 1.00e+00 | 9.040 | 1 | 1 | 1 |
GO:0090308 | regulation of methylation-dependent chromatin silencing | 1.90e-03 | 1.00e+00 | 9.040 | 1 | 1 | 1 |
GO:0032500 | muramyl dipeptide binding | 1.90e-03 | 1.00e+00 | 9.040 | 1 | 1 | 1 |
GO:0090081 | regulation of heart induction by regulation of canonical Wnt signaling pathway | 1.90e-03 | 1.00e+00 | 9.040 | 1 | 1 | 1 |
GO:0002710 | negative regulation of T cell mediated immunity | 1.90e-03 | 1.00e+00 | 9.040 | 1 | 1 | 1 |
GO:0060795 | cell fate commitment involved in formation of primary germ layer | 1.90e-03 | 1.00e+00 | 9.040 | 1 | 1 | 1 |
GO:0060177 | regulation of angiotensin metabolic process | 1.90e-03 | 1.00e+00 | 9.040 | 1 | 1 | 1 |
GO:0071608 | macrophage inflammatory protein-1 alpha production | 1.90e-03 | 1.00e+00 | 9.040 | 1 | 1 | 1 |
GO:0018160 | peptidyl-pyrromethane cofactor linkage | 1.90e-03 | 1.00e+00 | 9.040 | 1 | 1 | 1 |
GO:0002732 | positive regulation of dendritic cell cytokine production | 1.90e-03 | 1.00e+00 | 9.040 | 1 | 1 | 1 |
GO:2000629 | negative regulation of miRNA metabolic process | 1.90e-03 | 1.00e+00 | 9.040 | 1 | 1 | 1 |
GO:0004418 | hydroxymethylbilane synthase activity | 1.90e-03 | 1.00e+00 | 9.040 | 1 | 1 | 1 |
GO:2000363 | positive regulation of prostaglandin-E synthase activity | 1.90e-03 | 1.00e+00 | 9.040 | 1 | 1 | 1 |
GO:0032701 | negative regulation of interleukin-18 production | 1.90e-03 | 1.00e+00 | 9.040 | 1 | 1 | 1 |
GO:0046645 | positive regulation of gamma-delta T cell activation | 1.90e-03 | 1.00e+00 | 9.040 | 1 | 1 | 1 |
GO:0005634 | nucleus | 2.86e-03 | 1.00e+00 | 0.890 | 17 | 55 | 4828 |
GO:0060242 | contact inhibition | 3.80e-03 | 1.00e+00 | 8.040 | 1 | 1 | 2 |
GO:0009368 | endopeptidase Clp complex | 3.80e-03 | 1.00e+00 | 8.040 | 1 | 1 | 2 |
GO:0035419 | activation of MAPK activity involved in innate immune response | 3.80e-03 | 1.00e+00 | 8.040 | 1 | 1 | 2 |
GO:0000939 | condensed chromosome inner kinetochore | 3.80e-03 | 1.00e+00 | 8.040 | 1 | 1 | 2 |
GO:0009786 | regulation of asymmetric cell division | 3.80e-03 | 1.00e+00 | 8.040 | 1 | 1 | 2 |
GO:0090043 | regulation of tubulin deacetylation | 3.80e-03 | 1.00e+00 | 8.040 | 1 | 1 | 2 |
GO:0071389 | cellular response to mineralocorticoid stimulus | 3.80e-03 | 1.00e+00 | 8.040 | 1 | 1 | 2 |
GO:0060965 | negative regulation of gene silencing by miRNA | 3.80e-03 | 1.00e+00 | 8.040 | 1 | 1 | 2 |
GO:0006788 | heme oxidation | 3.80e-03 | 1.00e+00 | 8.040 | 1 | 1 | 2 |
GO:0014737 | positive regulation of muscle atrophy | 3.80e-03 | 1.00e+00 | 8.040 | 1 | 1 | 2 |
GO:0006965 | positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria | 3.80e-03 | 1.00e+00 | 8.040 | 1 | 1 | 2 |
GO:0035984 | cellular response to trichostatin A | 3.80e-03 | 1.00e+00 | 8.040 | 1 | 1 | 2 |
GO:0004392 | heme oxygenase (decyclizing) activity | 3.80e-03 | 1.00e+00 | 8.040 | 1 | 1 | 2 |
GO:0044212 | transcription regulatory region DNA binding | 4.09e-03 | 1.00e+00 | 3.207 | 3 | 5 | 171 |
GO:0007254 | JNK cascade | 4.20e-03 | 1.00e+00 | 4.368 | 2 | 2 | 51 |
GO:0000775 | chromosome, centromeric region | 4.36e-03 | 1.00e+00 | 4.340 | 2 | 3 | 52 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 4.70e-03 | 1.00e+00 | 2.160 | 5 | 10 | 589 |
GO:0036123 | histone H3-K9 dimethylation | 5.69e-03 | 1.00e+00 | 7.455 | 1 | 1 | 3 |
GO:0090022 | regulation of neutrophil chemotaxis | 5.69e-03 | 1.00e+00 | 7.455 | 1 | 1 | 3 |
GO:0000338 | protein deneddylation | 5.69e-03 | 1.00e+00 | 7.455 | 1 | 1 | 3 |
GO:0018076 | N-terminal peptidyl-lysine acetylation | 5.69e-03 | 1.00e+00 | 7.455 | 1 | 1 | 3 |
GO:0071225 | cellular response to muramyl dipeptide | 5.69e-03 | 1.00e+00 | 7.455 | 1 | 1 | 3 |
GO:0071459 | protein localization to chromosome, centromeric region | 5.69e-03 | 1.00e+00 | 7.455 | 1 | 1 | 3 |
GO:0010560 | positive regulation of glycoprotein biosynthetic process | 5.69e-03 | 1.00e+00 | 7.455 | 1 | 1 | 3 |
GO:0009595 | detection of biotic stimulus | 5.69e-03 | 1.00e+00 | 7.455 | 1 | 1 | 3 |
GO:0034136 | negative regulation of toll-like receptor 2 signaling pathway | 5.69e-03 | 1.00e+00 | 7.455 | 1 | 1 | 3 |
GO:0003130 | BMP signaling pathway involved in heart induction | 5.69e-03 | 1.00e+00 | 7.455 | 1 | 1 | 3 |
GO:0060585 | positive regulation of prostaglandin-endoperoxide synthase activity | 5.69e-03 | 1.00e+00 | 7.455 | 1 | 1 | 3 |
GO:0032481 | positive regulation of type I interferon production | 5.96e-03 | 1.00e+00 | 4.110 | 2 | 2 | 61 |
GO:0051716 | cellular response to stimulus | 7.58e-03 | 1.00e+00 | 7.040 | 1 | 2 | 4 |
GO:0000778 | condensed nuclear chromosome kinetochore | 7.58e-03 | 1.00e+00 | 7.040 | 1 | 1 | 4 |
GO:0097157 | pre-mRNA intronic binding | 7.58e-03 | 1.00e+00 | 7.040 | 1 | 1 | 4 |
GO:0060913 | cardiac cell fate determination | 7.58e-03 | 1.00e+00 | 7.040 | 1 | 1 | 4 |
GO:0018393 | internal peptidyl-lysine acetylation | 7.58e-03 | 1.00e+00 | 7.040 | 1 | 1 | 4 |
GO:2000110 | negative regulation of macrophage apoptotic process | 7.58e-03 | 1.00e+00 | 7.040 | 1 | 1 | 4 |
GO:0071224 | cellular response to peptidoglycan | 7.58e-03 | 1.00e+00 | 7.040 | 1 | 1 | 4 |
GO:0050871 | positive regulation of B cell activation | 7.58e-03 | 1.00e+00 | 7.040 | 1 | 1 | 4 |
GO:0010467 | gene expression | 7.99e-03 | 1.00e+00 | 1.976 | 5 | 27 | 669 |
GO:0000785 | chromatin | 8.44e-03 | 1.00e+00 | 3.850 | 2 | 2 | 73 |
GO:0001714 | endodermal cell fate specification | 9.46e-03 | 1.00e+00 | 6.718 | 1 | 1 | 5 |
GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor | 9.46e-03 | 1.00e+00 | 6.718 | 1 | 1 | 5 |
GO:0070934 | CRD-mediated mRNA stabilization | 9.46e-03 | 1.00e+00 | 6.718 | 1 | 2 | 5 |
GO:0002925 | positive regulation of humoral immune response mediated by circulating immunoglobulin | 9.46e-03 | 1.00e+00 | 6.718 | 1 | 1 | 5 |
GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly | 9.46e-03 | 1.00e+00 | 6.718 | 1 | 1 | 5 |
GO:0065004 | protein-DNA complex assembly | 9.46e-03 | 1.00e+00 | 6.718 | 1 | 1 | 5 |
GO:0070431 | nucleotide-binding oligomerization domain containing 2 signaling pathway | 9.46e-03 | 1.00e+00 | 6.718 | 1 | 1 | 5 |
GO:0033600 | negative regulation of mammary gland epithelial cell proliferation | 9.46e-03 | 1.00e+00 | 6.718 | 1 | 1 | 5 |
GO:0032057 | negative regulation of translational initiation in response to stress | 9.46e-03 | 1.00e+00 | 6.718 | 1 | 1 | 5 |
GO:0036124 | histone H3-K9 trimethylation | 9.46e-03 | 1.00e+00 | 6.718 | 1 | 1 | 5 |
GO:0002830 | positive regulation of type 2 immune response | 9.46e-03 | 1.00e+00 | 6.718 | 1 | 1 | 5 |
GO:0060298 | positive regulation of sarcomere organization | 9.46e-03 | 1.00e+00 | 6.718 | 1 | 1 | 5 |
GO:0032025 | response to cobalt ion | 9.46e-03 | 1.00e+00 | 6.718 | 1 | 1 | 5 |
GO:0050847 | progesterone receptor signaling pathway | 1.13e-02 | 1.00e+00 | 6.455 | 1 | 1 | 6 |
GO:0002381 | immunoglobulin production involved in immunoglobulin mediated immune response | 1.13e-02 | 1.00e+00 | 6.455 | 1 | 1 | 6 |
GO:0046974 | histone methyltransferase activity (H3-K9 specific) | 1.13e-02 | 1.00e+00 | 6.455 | 1 | 1 | 6 |
GO:0060744 | mammary gland branching involved in thelarche | 1.13e-02 | 1.00e+00 | 6.455 | 1 | 1 | 6 |
GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway | 1.13e-02 | 1.00e+00 | 6.455 | 1 | 1 | 6 |
GO:0070937 | CRD-mediated mRNA stability complex | 1.13e-02 | 1.00e+00 | 6.455 | 1 | 2 | 6 |
GO:0005851 | eukaryotic translation initiation factor 2B complex | 1.13e-02 | 1.00e+00 | 6.455 | 1 | 3 | 6 |
GO:0042167 | heme catabolic process | 1.13e-02 | 1.00e+00 | 6.455 | 1 | 1 | 6 |
GO:0002862 | negative regulation of inflammatory response to antigenic stimulus | 1.13e-02 | 1.00e+00 | 6.455 | 1 | 1 | 6 |
GO:0006333 | chromatin assembly or disassembly | 1.13e-02 | 1.00e+00 | 6.455 | 1 | 1 | 6 |
GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis | 1.13e-02 | 1.00e+00 | 6.455 | 1 | 1 | 6 |
GO:0005730 | nucleolus | 1.14e-02 | 1.00e+00 | 1.323 | 8 | 28 | 1684 |
GO:0051353 | positive regulation of oxidoreductase activity | 1.32e-02 | 1.00e+00 | 6.233 | 1 | 1 | 7 |
GO:0002606 | positive regulation of dendritic cell antigen processing and presentation | 1.32e-02 | 1.00e+00 | 6.233 | 1 | 1 | 7 |
GO:0032731 | positive regulation of interleukin-1 beta production | 1.32e-02 | 1.00e+00 | 6.233 | 1 | 1 | 7 |
GO:0006475 | internal protein amino acid acetylation | 1.32e-02 | 1.00e+00 | 6.233 | 1 | 1 | 7 |
GO:0001649 | osteoblast differentiation | 1.40e-02 | 1.00e+00 | 3.470 | 2 | 3 | 95 |
GO:0071456 | cellular response to hypoxia | 1.48e-02 | 1.00e+00 | 3.426 | 2 | 2 | 98 |
GO:0042582 | azurophil granule | 1.51e-02 | 1.00e+00 | 6.040 | 1 | 1 | 8 |
GO:0001055 | RNA polymerase II activity | 1.51e-02 | 1.00e+00 | 6.040 | 1 | 1 | 8 |
GO:0042754 | negative regulation of circadian rhythm | 1.51e-02 | 1.00e+00 | 6.040 | 1 | 1 | 8 |
GO:0006903 | vesicle targeting | 1.51e-02 | 1.00e+00 | 6.040 | 1 | 1 | 8 |
GO:0000780 | condensed nuclear chromosome, centromeric region | 1.51e-02 | 1.00e+00 | 6.040 | 1 | 1 | 8 |
GO:0050700 | CARD domain binding | 1.51e-02 | 1.00e+00 | 6.040 | 1 | 1 | 8 |
GO:0016779 | nucleotidyltransferase activity | 1.51e-02 | 1.00e+00 | 6.040 | 1 | 1 | 8 |
GO:0005829 | cytosol | 1.67e-02 | 1.00e+00 | 1.039 | 10 | 38 | 2562 |
GO:0071354 | cellular response to interleukin-6 | 1.70e-02 | 1.00e+00 | 5.870 | 1 | 1 | 9 |
GO:0035259 | glucocorticoid receptor binding | 1.70e-02 | 1.00e+00 | 5.870 | 1 | 1 | 9 |
GO:0045793 | positive regulation of cell size | 1.70e-02 | 1.00e+00 | 5.870 | 1 | 1 | 9 |
GO:0006782 | protoporphyrinogen IX biosynthetic process | 1.70e-02 | 1.00e+00 | 5.870 | 1 | 1 | 9 |
GO:0060765 | regulation of androgen receptor signaling pathway | 1.70e-02 | 1.00e+00 | 5.870 | 1 | 1 | 9 |
GO:0005832 | chaperonin-containing T-complex | 1.70e-02 | 1.00e+00 | 5.870 | 1 | 1 | 9 |
GO:0042834 | peptidoglycan binding | 1.70e-02 | 1.00e+00 | 5.870 | 1 | 1 | 9 |
GO:0032495 | response to muramyl dipeptide | 1.70e-02 | 1.00e+00 | 5.870 | 1 | 2 | 9 |
GO:0016032 | viral process | 1.84e-02 | 1.00e+00 | 1.963 | 4 | 16 | 540 |
GO:0002199 | zona pellucida receptor complex | 1.88e-02 | 1.00e+00 | 5.718 | 1 | 1 | 10 |
GO:0032703 | negative regulation of interleukin-2 production | 1.88e-02 | 1.00e+00 | 5.718 | 1 | 1 | 10 |
GO:1900153 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 1.88e-02 | 1.00e+00 | 5.718 | 1 | 1 | 10 |
GO:0051382 | kinetochore assembly | 1.88e-02 | 1.00e+00 | 5.718 | 1 | 1 | 10 |
GO:0016407 | acetyltransferase activity | 1.88e-02 | 1.00e+00 | 5.718 | 1 | 1 | 10 |
GO:0010944 | negative regulation of transcription by competitive promoter binding | 1.88e-02 | 1.00e+00 | 5.718 | 1 | 1 | 10 |
GO:0048387 | negative regulation of retinoic acid receptor signaling pathway | 2.07e-02 | 1.00e+00 | 5.581 | 1 | 1 | 11 |
GO:0030277 | maintenance of gastrointestinal epithelium | 2.07e-02 | 1.00e+00 | 5.581 | 1 | 1 | 11 |
GO:0060213 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening | 2.07e-02 | 1.00e+00 | 5.581 | 1 | 1 | 11 |
GO:0043923 | positive regulation by host of viral transcription | 2.07e-02 | 1.00e+00 | 5.581 | 1 | 1 | 11 |
GO:0035413 | positive regulation of catenin import into nucleus | 2.07e-02 | 1.00e+00 | 5.581 | 1 | 1 | 11 |
GO:0032740 | positive regulation of interleukin-17 production | 2.07e-02 | 1.00e+00 | 5.581 | 1 | 1 | 11 |
GO:0004535 | poly(A)-specific ribonuclease activity | 2.07e-02 | 1.00e+00 | 5.581 | 1 | 1 | 11 |
GO:0033160 | positive regulation of protein import into nucleus, translocation | 2.07e-02 | 1.00e+00 | 5.581 | 1 | 1 | 11 |
GO:2000036 | regulation of stem cell maintenance | 2.07e-02 | 1.00e+00 | 5.581 | 1 | 1 | 11 |
GO:0042975 | peroxisome proliferator activated receptor binding | 2.07e-02 | 1.00e+00 | 5.581 | 1 | 1 | 11 |
GO:0060391 | positive regulation of SMAD protein import into nucleus | 2.07e-02 | 1.00e+00 | 5.581 | 1 | 1 | 11 |
GO:0032874 | positive regulation of stress-activated MAPK cascade | 2.26e-02 | 1.00e+00 | 5.455 | 1 | 1 | 12 |
GO:0032695 | negative regulation of interleukin-12 production | 2.26e-02 | 1.00e+00 | 5.455 | 1 | 1 | 12 |
GO:0042581 | specific granule | 2.26e-02 | 1.00e+00 | 5.455 | 1 | 1 | 12 |
GO:0007140 | male meiosis | 2.44e-02 | 1.00e+00 | 5.340 | 1 | 1 | 13 |
GO:0042974 | retinoic acid receptor binding | 2.44e-02 | 1.00e+00 | 5.340 | 1 | 1 | 13 |
GO:0009416 | response to light stimulus | 2.44e-02 | 1.00e+00 | 5.340 | 1 | 1 | 13 |
GO:0042789 | mRNA transcription from RNA polymerase II promoter | 2.44e-02 | 1.00e+00 | 5.340 | 1 | 2 | 13 |
GO:0060766 | negative regulation of androgen receptor signaling pathway | 2.44e-02 | 1.00e+00 | 5.340 | 1 | 1 | 13 |
GO:0051019 | mitogen-activated protein kinase binding | 2.44e-02 | 1.00e+00 | 5.340 | 1 | 2 | 13 |
GO:0035198 | miRNA binding | 2.44e-02 | 1.00e+00 | 5.340 | 1 | 1 | 13 |
GO:0003682 | chromatin binding | 2.50e-02 | 1.00e+00 | 2.242 | 3 | 7 | 334 |
GO:0071480 | cellular response to gamma radiation | 2.63e-02 | 1.00e+00 | 5.233 | 1 | 1 | 14 |
GO:0004527 | exonuclease activity | 2.63e-02 | 1.00e+00 | 5.233 | 1 | 1 | 14 |
GO:0016045 | detection of bacterium | 2.63e-02 | 1.00e+00 | 5.233 | 1 | 1 | 14 |
GO:0005095 | GTPase inhibitor activity | 2.63e-02 | 1.00e+00 | 5.233 | 1 | 1 | 14 |
GO:0070542 | response to fatty acid | 2.63e-02 | 1.00e+00 | 5.233 | 1 | 1 | 14 |
GO:0051770 | positive regulation of nitric-oxide synthase biosynthetic process | 2.63e-02 | 1.00e+00 | 5.233 | 1 | 1 | 14 |
GO:0032993 | protein-DNA complex | 2.63e-02 | 1.00e+00 | 5.233 | 1 | 1 | 14 |
GO:0001824 | blastocyst development | 2.81e-02 | 1.00e+00 | 5.133 | 1 | 1 | 15 |
GO:0030014 | CCR4-NOT complex | 2.81e-02 | 1.00e+00 | 5.133 | 1 | 1 | 15 |
GO:0060749 | mammary gland alveolus development | 2.81e-02 | 1.00e+00 | 5.133 | 1 | 1 | 15 |
GO:1990090 | cellular response to nerve growth factor stimulus | 2.81e-02 | 1.00e+00 | 5.133 | 1 | 1 | 15 |
GO:0005665 | DNA-directed RNA polymerase II, core complex | 3.00e-02 | 1.00e+00 | 5.040 | 1 | 1 | 16 |
GO:0016746 | transferase activity, transferring acyl groups | 3.00e-02 | 1.00e+00 | 5.040 | 1 | 2 | 16 |
GO:0051603 | proteolysis involved in cellular protein catabolic process | 3.00e-02 | 1.00e+00 | 5.040 | 1 | 1 | 16 |
GO:0000132 | establishment of mitotic spindle orientation | 3.00e-02 | 1.00e+00 | 5.040 | 1 | 1 | 16 |
GO:0001056 | RNA polymerase III activity | 3.00e-02 | 1.00e+00 | 5.040 | 1 | 1 | 16 |
GO:0001829 | trophectodermal cell differentiation | 3.18e-02 | 1.00e+00 | 4.953 | 1 | 2 | 17 |
GO:0005666 | DNA-directed RNA polymerase III complex | 3.18e-02 | 1.00e+00 | 4.953 | 1 | 1 | 17 |
GO:0044130 | negative regulation of growth of symbiont in host | 3.18e-02 | 1.00e+00 | 4.953 | 1 | 1 | 17 |
GO:0001666 | response to hypoxia | 3.28e-02 | 1.00e+00 | 2.811 | 2 | 3 | 150 |
GO:0006386 | termination of RNA polymerase III transcription | 3.37e-02 | 1.00e+00 | 4.870 | 1 | 1 | 18 |
GO:0050718 | positive regulation of interleukin-1 beta secretion | 3.37e-02 | 1.00e+00 | 4.870 | 1 | 1 | 18 |
GO:0006385 | transcription elongation from RNA polymerase III promoter | 3.37e-02 | 1.00e+00 | 4.870 | 1 | 1 | 18 |
GO:0045773 | positive regulation of axon extension | 3.37e-02 | 1.00e+00 | 4.870 | 1 | 1 | 18 |
GO:0033613 | activating transcription factor binding | 3.37e-02 | 1.00e+00 | 4.870 | 1 | 1 | 18 |
GO:0032733 | positive regulation of interleukin-10 production | 3.55e-02 | 1.00e+00 | 4.792 | 1 | 2 | 19 |
GO:0035257 | nuclear hormone receptor binding | 3.55e-02 | 1.00e+00 | 4.792 | 1 | 1 | 19 |
GO:0071549 | cellular response to dexamethasone stimulus | 3.73e-02 | 1.00e+00 | 4.718 | 1 | 1 | 20 |
GO:0010942 | positive regulation of cell death | 3.73e-02 | 1.00e+00 | 4.718 | 1 | 1 | 20 |
GO:0002227 | innate immune response in mucosa | 3.73e-02 | 1.00e+00 | 4.718 | 1 | 1 | 20 |
GO:0005680 | anaphase-promoting complex | 3.73e-02 | 1.00e+00 | 4.718 | 1 | 1 | 20 |
GO:0014003 | oligodendrocyte development | 3.73e-02 | 1.00e+00 | 4.718 | 1 | 3 | 20 |
GO:0006783 | heme biosynthetic process | 3.73e-02 | 1.00e+00 | 4.718 | 1 | 1 | 20 |
GO:0000398 | mRNA splicing, via spliceosome | 3.90e-02 | 1.00e+00 | 2.674 | 2 | 9 | 165 |
GO:0000278 | mitotic cell cycle | 3.91e-02 | 1.00e+00 | 1.989 | 3 | 12 | 398 |
GO:0032967 | positive regulation of collagen biosynthetic process | 3.92e-02 | 1.00e+00 | 4.648 | 1 | 1 | 21 |
GO:0045862 | positive regulation of proteolysis | 3.92e-02 | 1.00e+00 | 4.648 | 1 | 2 | 21 |
GO:0000123 | histone acetyltransferase complex | 3.92e-02 | 1.00e+00 | 4.648 | 1 | 2 | 21 |
GO:0016575 | histone deacetylation | 3.92e-02 | 1.00e+00 | 4.648 | 1 | 1 | 21 |
GO:0005720 | nuclear heterochromatin | 4.10e-02 | 1.00e+00 | 4.581 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 4.10e-02 | 1.00e+00 | 4.581 | 1 | 1 | 22 |
GO:0001205 | RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | 4.10e-02 | 1.00e+00 | 4.581 | 1 | 2 | 22 |
GO:0031463 | Cul3-RING ubiquitin ligase complex | 4.28e-02 | 1.00e+00 | 4.517 | 1 | 1 | 23 |
GO:0045747 | positive regulation of Notch signaling pathway | 4.28e-02 | 1.00e+00 | 4.517 | 1 | 1 | 23 |
GO:0008135 | translation factor activity, nucleic acid binding | 4.46e-02 | 1.00e+00 | 4.455 | 1 | 2 | 24 |
GO:0050766 | positive regulation of phagocytosis | 4.46e-02 | 1.00e+00 | 4.455 | 1 | 1 | 24 |
GO:0032689 | negative regulation of interferon-gamma production | 4.46e-02 | 1.00e+00 | 4.455 | 1 | 1 | 24 |
GO:0043388 | positive regulation of DNA binding | 4.46e-02 | 1.00e+00 | 4.455 | 1 | 1 | 24 |
GO:0006363 | termination of RNA polymerase I transcription | 4.46e-02 | 1.00e+00 | 4.455 | 1 | 1 | 24 |
GO:0043425 | bHLH transcription factor binding | 4.46e-02 | 1.00e+00 | 4.455 | 1 | 1 | 24 |
GO:0005667 | transcription factor complex | 4.47e-02 | 1.00e+00 | 2.565 | 2 | 3 | 178 |
GO:0003714 | transcription corepressor activity | 4.52e-02 | 1.00e+00 | 2.556 | 2 | 5 | 179 |
GO:0045892 | negative regulation of transcription, DNA-templated | 4.57e-02 | 1.00e+00 | 1.897 | 3 | 7 | 424 |
GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening | 4.65e-02 | 1.00e+00 | 4.396 | 1 | 1 | 25 |
GO:0070423 | nucleotide-binding oligomerization domain containing signaling pathway | 4.65e-02 | 1.00e+00 | 4.396 | 1 | 1 | 25 |
GO:0003899 | DNA-directed RNA polymerase activity | 4.65e-02 | 1.00e+00 | 4.396 | 1 | 1 | 25 |
GO:0051059 | NF-kappaB binding | 4.65e-02 | 1.00e+00 | 4.396 | 1 | 2 | 25 |
GO:0032735 | positive regulation of interleukin-12 production | 4.65e-02 | 1.00e+00 | 4.396 | 1 | 2 | 25 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 4.75e-02 | 1.00e+00 | 2.517 | 2 | 5 | 184 |
GO:0035329 | hippo signaling | 4.83e-02 | 1.00e+00 | 4.340 | 1 | 1 | 26 |
GO:0031047 | gene silencing by RNA | 4.83e-02 | 1.00e+00 | 4.340 | 1 | 2 | 26 |
GO:0070979 | protein K11-linked ubiquitination | 4.83e-02 | 1.00e+00 | 4.340 | 1 | 1 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 4.83e-02 | 1.00e+00 | 4.340 | 1 | 1 | 26 |
GO:0061025 | membrane fusion | 4.83e-02 | 1.00e+00 | 4.340 | 1 | 1 | 26 |
GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic | 4.83e-02 | 1.00e+00 | 4.340 | 1 | 1 | 26 |
GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity | 4.83e-02 | 1.00e+00 | 4.340 | 1 | 1 | 26 |
GO:0032720 | negative regulation of tumor necrosis factor production | 5.01e-02 | 1.00e+00 | 4.285 | 1 | 2 | 27 |
GO:0000188 | inactivation of MAPK activity | 5.01e-02 | 1.00e+00 | 4.285 | 1 | 1 | 27 |
GO:0034080 | CENP-A containing nucleosome assembly | 5.01e-02 | 1.00e+00 | 4.285 | 1 | 2 | 27 |
GO:0048565 | digestive tract development | 5.01e-02 | 1.00e+00 | 4.285 | 1 | 1 | 27 |
GO:0007339 | binding of sperm to zona pellucida | 5.01e-02 | 1.00e+00 | 4.285 | 1 | 1 | 27 |
GO:0044822 | poly(A) RNA binding | 5.06e-02 | 1.00e+00 | 1.288 | 5 | 27 | 1078 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 5.16e-02 | 1.00e+00 | 1.493 | 4 | 10 | 748 |
GO:0003823 | antigen binding | 5.19e-02 | 1.00e+00 | 4.233 | 1 | 1 | 28 |
GO:0034612 | response to tumor necrosis factor | 5.19e-02 | 1.00e+00 | 4.233 | 1 | 1 | 28 |
GO:0000976 | transcription regulatory region sequence-specific DNA binding | 5.19e-02 | 1.00e+00 | 4.233 | 1 | 1 | 28 |
GO:0043967 | histone H4 acetylation | 5.19e-02 | 1.00e+00 | 4.233 | 1 | 1 | 28 |
GO:0050714 | positive regulation of protein secretion | 5.37e-02 | 1.00e+00 | 4.182 | 1 | 1 | 29 |
GO:0071897 | DNA biosynthetic process | 5.37e-02 | 1.00e+00 | 4.182 | 1 | 1 | 29 |
GO:0005737 | cytoplasm | 5.40e-02 | 1.00e+00 | 0.668 | 12 | 43 | 3976 |
GO:0006355 | regulation of transcription, DNA-templated | 5.50e-02 | 1.00e+00 | 1.254 | 5 | 13 | 1104 |
GO:0006370 | 7-methylguanosine mRNA capping | 5.55e-02 | 1.00e+00 | 4.133 | 1 | 2 | 30 |
GO:0006360 | transcription from RNA polymerase I promoter | 5.55e-02 | 1.00e+00 | 4.133 | 1 | 1 | 30 |
GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 5.55e-02 | 1.00e+00 | 4.133 | 1 | 1 | 30 |
GO:0043330 | response to exogenous dsRNA | 5.55e-02 | 1.00e+00 | 4.133 | 1 | 1 | 30 |
GO:0007094 | mitotic spindle assembly checkpoint | 5.73e-02 | 1.00e+00 | 4.086 | 1 | 3 | 31 |
GO:0006139 | nucleobase-containing compound metabolic process | 5.91e-02 | 1.00e+00 | 4.040 | 1 | 1 | 32 |
GO:0043491 | protein kinase B signaling | 5.91e-02 | 1.00e+00 | 4.040 | 1 | 1 | 32 |
GO:1903507 | negative regulation of nucleic acid-templated transcription | 5.91e-02 | 1.00e+00 | 4.040 | 1 | 1 | 32 |
GO:0001104 | RNA polymerase II transcription cofactor activity | 6.09e-02 | 1.00e+00 | 3.996 | 1 | 3 | 33 |
GO:0016592 | mediator complex | 6.44e-02 | 1.00e+00 | 3.911 | 1 | 5 | 35 |
GO:0071333 | cellular response to glucose stimulus | 6.44e-02 | 1.00e+00 | 3.911 | 1 | 1 | 35 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 6.57e-02 | 1.00e+00 | 1.377 | 4 | 13 | 811 |
GO:0032755 | positive regulation of interleukin-6 production | 6.62e-02 | 1.00e+00 | 3.870 | 1 | 2 | 36 |
GO:0001102 | RNA polymerase II activating transcription factor binding | 6.80e-02 | 1.00e+00 | 3.831 | 1 | 1 | 37 |
GO:0051084 | 'de novo' posttranslational protein folding | 6.80e-02 | 1.00e+00 | 3.831 | 1 | 1 | 37 |
GO:0032760 | positive regulation of tumor necrosis factor production | 6.80e-02 | 1.00e+00 | 3.831 | 1 | 1 | 37 |
GO:0001756 | somitogenesis | 6.98e-02 | 1.00e+00 | 3.792 | 1 | 1 | 38 |
GO:0050681 | androgen receptor binding | 6.98e-02 | 1.00e+00 | 3.792 | 1 | 1 | 38 |
GO:0006383 | transcription from RNA polymerase III promoter | 7.15e-02 | 1.00e+00 | 3.755 | 1 | 3 | 39 |
GO:0031490 | chromatin DNA binding | 7.15e-02 | 1.00e+00 | 3.755 | 1 | 1 | 39 |
GO:0008380 | RNA splicing | 7.15e-02 | 1.00e+00 | 2.182 | 2 | 14 | 232 |
GO:0071407 | cellular response to organic cyclic compound | 7.15e-02 | 1.00e+00 | 3.755 | 1 | 3 | 39 |
GO:0032092 | positive regulation of protein binding | 7.15e-02 | 1.00e+00 | 3.755 | 1 | 1 | 39 |
GO:0046332 | SMAD binding | 7.33e-02 | 1.00e+00 | 3.718 | 1 | 1 | 40 |
GO:0009408 | response to heat | 7.33e-02 | 1.00e+00 | 3.718 | 1 | 2 | 40 |
GO:0035019 | somatic stem cell maintenance | 7.33e-02 | 1.00e+00 | 3.718 | 1 | 2 | 40 |
GO:0070301 | cellular response to hydrogen peroxide | 7.51e-02 | 1.00e+00 | 3.683 | 1 | 1 | 41 |
GO:0051259 | protein oligomerization | 7.51e-02 | 1.00e+00 | 3.683 | 1 | 1 | 41 |
GO:0007519 | skeletal muscle tissue development | 7.51e-02 | 1.00e+00 | 3.683 | 1 | 2 | 41 |
GO:0003713 | transcription coactivator activity | 7.52e-02 | 1.00e+00 | 2.139 | 2 | 7 | 239 |
GO:0035914 | skeletal muscle cell differentiation | 7.68e-02 | 1.00e+00 | 3.648 | 1 | 1 | 42 |
GO:0071320 | cellular response to cAMP | 7.68e-02 | 1.00e+00 | 3.648 | 1 | 1 | 42 |
GO:0035872 | nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway | 7.86e-02 | 1.00e+00 | 3.614 | 1 | 1 | 43 |
GO:0004402 | histone acetyltransferase activity | 7.86e-02 | 1.00e+00 | 3.614 | 1 | 1 | 43 |
GO:0008134 | transcription factor binding | 7.91e-02 | 1.00e+00 | 2.098 | 2 | 6 | 246 |
GO:0006892 | post-Golgi vesicle-mediated transport | 8.04e-02 | 1.00e+00 | 3.581 | 1 | 1 | 44 |
GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | 8.04e-02 | 1.00e+00 | 3.581 | 1 | 1 | 44 |
GO:0050434 | positive regulation of viral transcription | 8.04e-02 | 1.00e+00 | 3.581 | 1 | 2 | 44 |
GO:0043966 | histone H3 acetylation | 8.21e-02 | 1.00e+00 | 3.548 | 1 | 1 | 45 |
GO:0001047 | core promoter binding | 8.39e-02 | 1.00e+00 | 3.517 | 1 | 2 | 46 |
GO:0044297 | cell body | 8.39e-02 | 1.00e+00 | 3.517 | 1 | 1 | 46 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 8.39e-02 | 1.00e+00 | 3.517 | 1 | 1 | 46 |
GO:0045727 | positive regulation of translation | 8.39e-02 | 1.00e+00 | 3.517 | 1 | 2 | 46 |
GO:0043434 | response to peptide hormone | 8.39e-02 | 1.00e+00 | 3.517 | 1 | 2 | 46 |
GO:0050727 | regulation of inflammatory response | 8.56e-02 | 1.00e+00 | 3.486 | 1 | 1 | 47 |
GO:0048511 | rhythmic process | 8.56e-02 | 1.00e+00 | 3.486 | 1 | 2 | 47 |
GO:0003743 | translation initiation factor activity | 8.91e-02 | 1.00e+00 | 3.426 | 1 | 5 | 49 |
GO:0050830 | defense response to Gram-positive bacterium | 8.91e-02 | 1.00e+00 | 3.426 | 1 | 1 | 49 |
GO:0005778 | peroxisomal membrane | 9.08e-02 | 1.00e+00 | 3.396 | 1 | 2 | 50 |
GO:0035690 | cellular response to drug | 9.08e-02 | 1.00e+00 | 3.396 | 1 | 2 | 50 |
GO:0031398 | positive regulation of protein ubiquitination | 9.43e-02 | 1.00e+00 | 3.340 | 1 | 1 | 52 |
GO:0009611 | response to wounding | 9.60e-02 | 1.00e+00 | 3.312 | 1 | 1 | 53 |
GO:0006952 | defense response | 9.60e-02 | 1.00e+00 | 3.312 | 1 | 1 | 53 |
GO:0000288 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 9.60e-02 | 1.00e+00 | 3.312 | 1 | 2 | 53 |
GO:0090305 | nucleic acid phosphodiester bond hydrolysis | 9.77e-02 | 1.00e+00 | 3.285 | 1 | 1 | 54 |
GO:0007623 | circadian rhythm | 9.77e-02 | 1.00e+00 | 3.285 | 1 | 2 | 54 |
GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process | 9.77e-02 | 1.00e+00 | 3.285 | 1 | 1 | 54 |
GO:0051403 | stress-activated MAPK cascade | 9.77e-02 | 1.00e+00 | 3.285 | 1 | 2 | 54 |
GO:0050679 | positive regulation of epithelial cell proliferation | 9.77e-02 | 1.00e+00 | 3.285 | 1 | 1 | 54 |
GO:0008233 | peptidase activity | 9.94e-02 | 1.00e+00 | 3.259 | 1 | 1 | 55 |
GO:0051592 | response to calcium ion | 9.94e-02 | 1.00e+00 | 3.259 | 1 | 1 | 55 |
GO:0002039 | p53 binding | 9.94e-02 | 1.00e+00 | 3.259 | 1 | 3 | 55 |
GO:0046330 | positive regulation of JNK cascade | 9.94e-02 | 1.00e+00 | 3.259 | 1 | 1 | 55 |
GO:0000932 | cytoplasmic mRNA processing body | 1.01e-01 | 1.00e+00 | 3.233 | 1 | 2 | 56 |
GO:0071300 | cellular response to retinoic acid | 1.01e-01 | 1.00e+00 | 3.233 | 1 | 1 | 56 |
GO:0043627 | response to estrogen | 1.03e-01 | 1.00e+00 | 3.207 | 1 | 1 | 57 |
GO:0019899 | enzyme binding | 1.03e-01 | 1.00e+00 | 1.870 | 2 | 3 | 288 |
GO:0006879 | cellular iron ion homeostasis | 1.03e-01 | 1.00e+00 | 3.207 | 1 | 1 | 57 |
GO:0006396 | RNA processing | 1.08e-01 | 1.00e+00 | 3.133 | 1 | 4 | 60 |
GO:0008013 | beta-catenin binding | 1.08e-01 | 1.00e+00 | 3.133 | 1 | 4 | 60 |
GO:0003677 | DNA binding | 1.09e-01 | 1.00e+00 | 0.962 | 5 | 16 | 1351 |
GO:0016567 | protein ubiquitination | 1.10e-01 | 1.00e+00 | 1.816 | 2 | 5 | 299 |
GO:0045087 | innate immune response | 1.10e-01 | 1.00e+00 | 1.358 | 3 | 4 | 616 |
GO:0005743 | mitochondrial inner membrane | 1.11e-01 | 1.00e+00 | 1.811 | 2 | 3 | 300 |
GO:0043234 | protein complex | 1.11e-01 | 1.00e+00 | 1.811 | 2 | 4 | 300 |
GO:0019903 | protein phosphatase binding | 1.13e-01 | 1.00e+00 | 3.063 | 1 | 1 | 63 |
GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | 1.13e-01 | 1.00e+00 | 3.063 | 1 | 1 | 63 |
GO:0006417 | regulation of translation | 1.13e-01 | 1.00e+00 | 3.063 | 1 | 1 | 63 |
GO:0032088 | negative regulation of NF-kappaB transcription factor activity | 1.15e-01 | 1.00e+00 | 3.040 | 1 | 2 | 64 |
GO:0009749 | response to glucose | 1.15e-01 | 1.00e+00 | 3.040 | 1 | 2 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.16e-01 | 1.00e+00 | 3.018 | 1 | 3 | 65 |
GO:0034166 | toll-like receptor 10 signaling pathway | 1.16e-01 | 1.00e+00 | 3.018 | 1 | 2 | 65 |
GO:0034146 | toll-like receptor 5 signaling pathway | 1.16e-01 | 1.00e+00 | 3.018 | 1 | 2 | 65 |
GO:0006368 | transcription elongation from RNA polymerase II promoter | 1.20e-01 | 1.00e+00 | 2.974 | 1 | 3 | 67 |
GO:0006338 | chromatin remodeling | 1.22e-01 | 1.00e+00 | 2.953 | 1 | 1 | 68 |
GO:0006289 | nucleotide-excision repair | 1.23e-01 | 1.00e+00 | 2.932 | 1 | 1 | 69 |
GO:0003697 | single-stranded DNA binding | 1.23e-01 | 1.00e+00 | 2.932 | 1 | 2 | 69 |
GO:0006887 | exocytosis | 1.23e-01 | 1.00e+00 | 2.932 | 1 | 1 | 69 |
GO:0000786 | nucleosome | 1.25e-01 | 1.00e+00 | 2.911 | 1 | 1 | 70 |
GO:0042742 | defense response to bacterium | 1.25e-01 | 1.00e+00 | 2.911 | 1 | 1 | 70 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.25e-01 | 1.00e+00 | 2.911 | 1 | 4 | 70 |
GO:0038123 | toll-like receptor TLR1:TLR2 signaling pathway | 1.27e-01 | 1.00e+00 | 2.890 | 1 | 2 | 71 |
GO:0038124 | toll-like receptor TLR6:TLR2 signaling pathway | 1.27e-01 | 1.00e+00 | 2.890 | 1 | 2 | 71 |
GO:0007584 | response to nutrient | 1.28e-01 | 1.00e+00 | 2.870 | 1 | 1 | 72 |
GO:0034162 | toll-like receptor 9 signaling pathway | 1.28e-01 | 1.00e+00 | 2.870 | 1 | 2 | 72 |
GO:0010468 | regulation of gene expression | 1.28e-01 | 1.00e+00 | 2.870 | 1 | 1 | 72 |
GO:0008021 | synaptic vesicle | 1.30e-01 | 1.00e+00 | 2.850 | 1 | 2 | 73 |
GO:0008283 | cell proliferation | 1.30e-01 | 1.00e+00 | 1.670 | 2 | 3 | 331 |
GO:0034134 | toll-like receptor 2 signaling pathway | 1.30e-01 | 1.00e+00 | 2.850 | 1 | 2 | 73 |
GO:0005085 | guanyl-nucleotide exchange factor activity | 1.32e-01 | 1.00e+00 | 2.831 | 1 | 2 | 74 |
GO:0042826 | histone deacetylase binding | 1.32e-01 | 1.00e+00 | 2.831 | 1 | 2 | 74 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.32e-01 | 1.00e+00 | 2.831 | 1 | 4 | 74 |
GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | 1.33e-01 | 1.00e+00 | 2.811 | 1 | 1 | 75 |
GO:0005739 | mitochondrion | 1.34e-01 | 1.00e+00 | 1.010 | 4 | 16 | 1046 |
GO:0030324 | lung development | 1.35e-01 | 1.00e+00 | 2.792 | 1 | 1 | 76 |
GO:0035666 | TRIF-dependent toll-like receptor signaling pathway | 1.35e-01 | 1.00e+00 | 2.792 | 1 | 2 | 76 |
GO:0030182 | neuron differentiation | 1.36e-01 | 1.00e+00 | 2.773 | 1 | 1 | 77 |
GO:0000981 | sequence-specific DNA binding RNA polymerase II transcription factor activity | 1.36e-01 | 1.00e+00 | 2.773 | 1 | 2 | 77 |
GO:0002756 | MyD88-independent toll-like receptor signaling pathway | 1.38e-01 | 1.00e+00 | 2.755 | 1 | 2 | 78 |
GO:0006334 | nucleosome assembly | 1.40e-01 | 1.00e+00 | 2.736 | 1 | 3 | 79 |
GO:0071013 | catalytic step 2 spliceosome | 1.40e-01 | 1.00e+00 | 2.736 | 1 | 3 | 79 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.40e-01 | 1.00e+00 | 2.736 | 1 | 4 | 79 |
GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | 1.41e-01 | 1.00e+00 | 2.718 | 1 | 3 | 80 |
GO:0034138 | toll-like receptor 3 signaling pathway | 1.41e-01 | 1.00e+00 | 2.718 | 1 | 2 | 80 |
GO:0001889 | liver development | 1.45e-01 | 1.00e+00 | 2.683 | 1 | 2 | 82 |
GO:0009653 | anatomical structure morphogenesis | 1.53e-01 | 1.00e+00 | 2.597 | 1 | 1 | 87 |
GO:0045471 | response to ethanol | 1.54e-01 | 1.00e+00 | 2.581 | 1 | 1 | 88 |
GO:0009887 | organ morphogenesis | 1.56e-01 | 1.00e+00 | 2.565 | 1 | 1 | 89 |
GO:0000187 | activation of MAPK activity | 1.58e-01 | 1.00e+00 | 2.548 | 1 | 2 | 90 |
GO:0016363 | nuclear matrix | 1.61e-01 | 1.00e+00 | 2.517 | 1 | 5 | 92 |
GO:0051091 | positive regulation of sequence-specific DNA binding transcription factor activity | 1.62e-01 | 1.00e+00 | 2.501 | 1 | 2 | 93 |
GO:0051082 | unfolded protein binding | 1.66e-01 | 1.00e+00 | 2.470 | 1 | 3 | 95 |
GO:0034142 | toll-like receptor 4 signaling pathway | 1.67e-01 | 1.00e+00 | 2.455 | 1 | 2 | 96 |
GO:0051726 | regulation of cell cycle | 1.77e-01 | 1.00e+00 | 2.368 | 1 | 4 | 102 |
GO:0001934 | positive regulation of protein phosphorylation | 1.86e-01 | 1.00e+00 | 2.285 | 1 | 1 | 108 |
GO:0002224 | toll-like receptor signaling pathway | 1.88e-01 | 1.00e+00 | 2.272 | 1 | 2 | 109 |
GO:0070374 | positive regulation of ERK1 and ERK2 cascade | 1.89e-01 | 1.00e+00 | 2.259 | 1 | 1 | 110 |
GO:0009986 | cell surface | 1.91e-01 | 1.00e+00 | 1.319 | 2 | 4 | 422 |
GO:0030308 | negative regulation of cell growth | 1.94e-01 | 1.00e+00 | 2.220 | 1 | 2 | 113 |
GO:0030529 | ribonucleoprotein complex | 1.95e-01 | 1.00e+00 | 2.207 | 1 | 6 | 114 |
GO:0004252 | serine-type endopeptidase activity | 2.03e-01 | 1.00e+00 | 2.145 | 1 | 1 | 119 |
GO:0032496 | response to lipopolysaccharide | 2.08e-01 | 1.00e+00 | 2.110 | 1 | 1 | 122 |
GO:0003676 | nucleic acid binding | 2.08e-01 | 1.00e+00 | 2.110 | 1 | 2 | 122 |
GO:0006325 | chromatin organization | 2.09e-01 | 1.00e+00 | 2.098 | 1 | 3 | 123 |
GO:0051092 | positive regulation of NF-kappaB transcription factor activity | 2.12e-01 | 1.00e+00 | 2.074 | 1 | 1 | 125 |
GO:0007219 | Notch signaling pathway | 2.12e-01 | 1.00e+00 | 2.074 | 1 | 2 | 125 |
GO:0006413 | translational initiation | 2.21e-01 | 1.00e+00 | 2.007 | 1 | 4 | 131 |
GO:0031982 | vesicle | 2.26e-01 | 1.00e+00 | 1.974 | 1 | 2 | 134 |
GO:0000086 | G2/M transition of mitotic cell cycle | 2.30e-01 | 1.00e+00 | 1.942 | 1 | 3 | 137 |
GO:0045202 | synapse | 2.35e-01 | 1.00e+00 | 1.911 | 1 | 1 | 140 |
GO:0007507 | heart development | 2.36e-01 | 1.00e+00 | 1.901 | 1 | 2 | 141 |
GO:0042802 | identical protein binding | 2.39e-01 | 1.00e+00 | 1.101 | 2 | 6 | 491 |
GO:0044267 | cellular protein metabolic process | 2.42e-01 | 1.00e+00 | 1.089 | 2 | 7 | 495 |
GO:0061024 | membrane organization | 2.43e-01 | 1.00e+00 | 1.850 | 1 | 1 | 146 |
GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | 2.46e-01 | 1.00e+00 | 1.831 | 1 | 1 | 148 |
GO:0010628 | positive regulation of gene expression | 2.48e-01 | 1.00e+00 | 1.821 | 1 | 2 | 149 |
GO:0006457 | protein folding | 2.48e-01 | 1.00e+00 | 1.821 | 1 | 1 | 149 |
GO:0051260 | protein homooligomerization | 2.49e-01 | 1.00e+00 | 1.811 | 1 | 1 | 150 |
GO:0042981 | regulation of apoptotic process | 2.51e-01 | 1.00e+00 | 1.802 | 1 | 3 | 151 |
GO:0006974 | cellular response to DNA damage stimulus | 2.61e-01 | 1.00e+00 | 1.736 | 1 | 4 | 158 |
GO:0043005 | neuron projection | 2.65e-01 | 1.00e+00 | 1.709 | 1 | 4 | 161 |
GO:0007165 | signal transduction | 2.69e-01 | 1.00e+00 | 0.733 | 3 | 8 | 950 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 2.75e-01 | 1.00e+00 | 1.648 | 1 | 3 | 168 |
GO:0007049 | cell cycle | 2.87e-01 | 1.00e+00 | 1.573 | 1 | 4 | 177 |
GO:0031625 | ubiquitin protein ligase binding | 2.91e-01 | 1.00e+00 | 1.548 | 1 | 2 | 180 |
GO:0032403 | protein complex binding | 2.98e-01 | 1.00e+00 | 1.509 | 1 | 2 | 185 |
GO:0043547 | positive regulation of GTPase activity | 3.05e-01 | 1.00e+00 | 1.470 | 1 | 2 | 190 |
GO:0008270 | zinc ion binding | 3.31e-01 | 1.00e+00 | 0.566 | 3 | 11 | 1067 |
GO:0001701 | in utero embryonic development | 3.31e-01 | 1.00e+00 | 1.326 | 1 | 2 | 210 |
GO:0004871 | signal transducer activity | 3.39e-01 | 1.00e+00 | 1.285 | 1 | 1 | 216 |
GO:0070062 | extracellular vesicular exosome | 3.41e-01 | 1.00e+00 | 0.328 | 6 | 15 | 2516 |
GO:0016071 | mRNA metabolic process | 3.47e-01 | 1.00e+00 | 1.239 | 1 | 8 | 223 |
GO:0006351 | transcription, DNA-templated | 3.55e-01 | 1.00e+00 | 0.410 | 4 | 17 | 1585 |
GO:0007067 | mitotic nuclear division | 3.57e-01 | 1.00e+00 | 1.188 | 1 | 4 | 231 |
GO:0005759 | mitochondrial matrix | 3.60e-01 | 1.00e+00 | 1.176 | 1 | 4 | 233 |
GO:0006412 | translation | 3.62e-01 | 1.00e+00 | 1.164 | 1 | 5 | 235 |
GO:0007399 | nervous system development | 3.75e-01 | 1.00e+00 | 1.104 | 1 | 3 | 245 |
GO:0016070 | RNA metabolic process | 3.77e-01 | 1.00e+00 | 1.092 | 1 | 8 | 247 |
GO:0004842 | ubiquitin-protein transferase activity | 3.88e-01 | 1.00e+00 | 1.040 | 1 | 5 | 256 |
GO:0005874 | microtubule | 3.90e-01 | 1.00e+00 | 1.029 | 1 | 3 | 258 |
GO:0006281 | DNA repair | 3.97e-01 | 1.00e+00 | 0.996 | 1 | 4 | 264 |
GO:0006357 | regulation of transcription from RNA polymerase II promoter | 4.10e-01 | 1.00e+00 | 0.937 | 1 | 4 | 275 |
GO:0016020 | membrane | 4.27e-01 | 1.00e+00 | 0.270 | 4 | 27 | 1746 |
GO:0005856 | cytoskeleton | 4.50e-01 | 1.00e+00 | 0.759 | 1 | 2 | 311 |
GO:0035556 | intracellular signal transduction | 4.56e-01 | 1.00e+00 | 0.732 | 1 | 2 | 317 |
GO:0019901 | protein kinase binding | 4.59e-01 | 1.00e+00 | 0.718 | 1 | 4 | 320 |
GO:0030154 | cell differentiation | 4.64e-01 | 1.00e+00 | 0.696 | 1 | 2 | 325 |
GO:0005524 | ATP binding | 4.81e-01 | 1.00e+00 | 0.222 | 3 | 13 | 1354 |
GO:0003723 | RNA binding | 4.95e-01 | 1.00e+00 | 0.569 | 1 | 15 | 355 |
GO:0030054 | cell junction | 4.96e-01 | 1.00e+00 | 0.565 | 1 | 3 | 356 |
GO:0015031 | protein transport | 4.97e-01 | 1.00e+00 | 0.560 | 1 | 2 | 357 |
GO:0043565 | sequence-specific DNA binding | 5.04e-01 | 1.00e+00 | 0.528 | 1 | 3 | 365 |
GO:0008285 | negative regulation of cell proliferation | 5.06e-01 | 1.00e+00 | 0.521 | 1 | 4 | 367 |
GO:0005925 | focal adhesion | 5.09e-01 | 1.00e+00 | 0.509 | 1 | 2 | 370 |
GO:0046982 | protein heterodimerization activity | 5.36e-01 | 1.00e+00 | 0.400 | 1 | 3 | 399 |
GO:0006508 | proteolysis | 5.46e-01 | 1.00e+00 | 0.361 | 1 | 2 | 410 |
GO:0045893 | positive regulation of transcription, DNA-templated | 6.09e-01 | 1.00e+00 | 0.112 | 1 | 6 | 487 |
GO:0055085 | transmembrane transport | 6.30e-01 | 1.00e+00 | 0.035 | 1 | 5 | 514 |
GO:0006915 | apoptotic process | 6.69e-01 | 1.00e+00 | -0.117 | 1 | 8 | 571 |
GO:0005789 | endoplasmic reticulum membrane | 7.09e-01 | 1.00e+00 | -0.273 | 1 | 2 | 636 |
GO:0044281 | small molecule metabolic process | 7.17e-01 | 1.00e+00 | -0.298 | 2 | 12 | 1295 |
GO:0005887 | integral component of plasma membrane | 8.48e-01 | 1.00e+00 | -0.868 | 1 | 1 | 961 |
GO:0005615 | extracellular space | 8.62e-01 | 1.00e+00 | -0.940 | 1 | 4 | 1010 |
GO:0005886 | plasma membrane | 9.24e-01 | 1.00e+00 | -0.843 | 3 | 14 | 2834 |
GO:0046872 | metal ion binding | 9.46e-01 | 1.00e+00 | -1.476 | 1 | 6 | 1465 |
GO:0016021 | integral component of membrane | 9.94e-01 | 1.00e+00 | -2.238 | 1 | 7 | 2483 |