NOD2

Genes (1)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
NOD2	64127	2	-1.921	2.797	26	-	-

Gene info in the NCBI database: NOD2

2 meta-subnetworks

Subnetwork ID	Size	Highlighted genes
meta-reg-snw-3145	3	31
meta-int-snw-10980	2	23

Related GO terms (98)

Accession number	Name	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005515	protein binding	77	6127
GO:0005737	cytoplasm	43	3976
GO:0002830	positive regulation of type 2 immune response	1	5
GO:0000187	activation of MAPK activity	2	90
GO:0032735	positive regulation of interleukin-12 production	2	25
GO:0032500	muramyl dipeptide binding	1	1
GO:0035419	activation of MAPK activity involved in innate immune response	1	2
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	1	7
GO:0005829	cytosol	38	2562
GO:0051403	stress-activated MAPK cascade	2	54
GO:2000110	negative regulation of macrophage apoptotic process	1	4
GO:0006952	defense response	1	53
GO:0050700	CARD domain binding	1	8
GO:0043330	response to exogenous dsRNA	1	30
GO:0034142	toll-like receptor 4 signaling pathway	2	96
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	3	80
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	1	75
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	1	148
GO:0051092	positive regulation of NF-kappaB transcription factor activity	1	125
GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway	2	71
GO:0070374	positive regulation of ERK1 and ERK2 cascade	1	110
GO:0002367	cytokine production involved in immune response	1	1
GO:0034146	toll-like receptor 5 signaling pathway	2	65
GO:0034134	toll-like receptor 2 signaling pathway	2	73
GO:0032496	response to lipopolysaccharide	1	122
GO:0009986	cell surface	4	422
GO:0032701	negative regulation of interleukin-18 production	1	1
GO:0032495	response to muramyl dipeptide	2	9
GO:0005886	plasma membrane	14	2834
GO:0051353	positive regulation of oxidoreductase activity	1	7
GO:0034162	toll-like receptor 9 signaling pathway	2	72
GO:0006965	positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria	1	2
GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway	2	71
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	2	76
GO:0016045	detection of bacterium	1	14
GO:0032088	negative regulation of NF-kappaB transcription factor activity	2	64
GO:0030277	maintenance of gastrointestinal epithelium	1	11
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	13	811
GO:0005524	ATP binding	13	1354
GO:0031982	vesicle	2	134
GO:0009595	detection of biotic stimulus	1	3
GO:0050679	positive regulation of epithelial cell proliferation	1	54
GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	1	43
GO:0090022	regulation of neutrophil chemotaxis	1	3
GO:0035556	intracellular signal transduction	2	317
GO:0071224	cellular response to peptidoglycan	1	4
GO:0032874	positive regulation of stress-activated MAPK cascade	1	12
GO:0002224	toll-like receptor signaling pathway	2	109
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	1	25
GO:0032498	detection of muramyl dipeptide	1	1
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	1	5
GO:0050718	positive regulation of interleukin-1 beta secretion	1	18
GO:0008180	COP9 signalosome	6	34
GO:0042742	defense response to bacterium	1	70
GO:0050830	defense response to Gram-positive bacterium	1	49
GO:0044130	negative regulation of growth of symbiont in host	1	17
GO:0002710	negative regulation of T cell mediated immunity	1	1
GO:0060585	positive regulation of prostaglandin-endoperoxide synthase activity	1	3
GO:0032695	negative regulation of interleukin-12 production	1	12
GO:0034166	toll-like receptor 10 signaling pathway	2	65
GO:0019901	protein kinase binding	4	320
GO:0071225	cellular response to muramyl dipeptide	1	3
GO:0046645	positive regulation of gamma-delta T cell activation	1	1
GO:0031398	positive regulation of protein ubiquitination	1	52
GO:0032755	positive regulation of interleukin-6 production	2	36
GO:0002732	positive regulation of dendritic cell cytokine production	1	1
GO:0034136	negative regulation of toll-like receptor 2 signaling pathway	1	3
GO:0046330	positive regulation of JNK cascade	1	55
GO:0007254	JNK cascade	2	51
GO:0051259	protein oligomerization	1	41
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	1	14
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	1	26
GO:0032703	negative regulation of interleukin-2 production	1	10
GO:0032720	negative regulation of tumor necrosis factor production	2	27
GO:0045087	innate immune response	4	616
GO:0050766	positive regulation of phagocytosis	1	24
GO:0007584	response to nutrient	1	72
GO:2000363	positive regulation of prostaglandin-E synthase activity	1	1
GO:0034138	toll-like receptor 3 signaling pathway	2	80
GO:0032689	negative regulation of interferon-gamma production	1	24
GO:0032731	positive regulation of interleukin-1 beta production	1	7
GO:0043234	protein complex	4	300
GO:0071407	cellular response to organic cyclic compound	3	39
GO:0005856	cytoskeleton	2	311
GO:0050871	positive regulation of B cell activation	1	4
GO:0032733	positive regulation of interleukin-10 production	2	19
GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	1	6
GO:0032740	positive regulation of interleukin-17 production	1	11
GO:0002227	innate immune response in mucosa	1	20
GO:0002756	MyD88-independent toll-like receptor signaling pathway	2	78
GO:0002862	negative regulation of inflammatory response to antigenic stimulus	1	6
GO:0071608	macrophage inflammatory protein-1 alpha production	1	1
GO:0032760	positive regulation of tumor necrosis factor production	1	37
GO:0019899	enzyme binding	3	288
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	1	5
GO:0050727	regulation of inflammatory response	1	47
GO:0045747	positive regulation of Notch signaling pathway	1	23
GO:0042834	peptidoglycan binding	1	9

chia-Fav

NOD2

Genes (1)

Gene info in the NCBI database: NOD2

2 meta-subnetworks

Related GO terms (98)