meta-int-snw-9232

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-11277 wolf-screen-ratio-mammosphere-adherent 0.882 1.09e-07 9.11e-04 1.96e-03 10 9
int-snw-9232 wolf-screen-ratio-mammosphere-adherent 0.978 3.18e-17 9.34e-04 1.96e-02 9 6
wolf-screen-ratio-mammosphere-adherent-meta-int-snw-9232 subnetwork

Genes (16)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
PSMB1 5689 610.6880.901113Yes-
RBX1 9978 1151.1850.934148Yes-
PTTG1 9232 2-0.1550.97832--
PSMB7 5695 1180.9820.93490Yes-
HNRNPC 3183 1081.8120.973181Yes-
TREX1 11277 51-0.0510.88291Yes-
ATP6V1B2 526 530.8811.076278--
RPSA 3921 1201.3271.151152Yes-
CAD 790 910.8070.973400--
RPA2 6118 961.2501.15176Yes-
CDC16 8881 530.9501.02080Yes-
PSMB2 5690 1160.8770.956169Yes-
ACTB 60 1341.1531.151610Yes-
PSMD11 5717 1241.0951.106218Yes-
RUVBL2 10856 950.6930.956532Yes-
RAN 5901 890.6320.899258Yes-

Interactions (40)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
CAD 790 CDC16 8881 pp -- int.I2D: IntAct_Yeast
PSMB2 5690 TREX1 11277 pd < reg.ITFP.txt: no annot
CAD 790 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMB1 5689 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, MINT, YeastHigh, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast;
int.Mint: MI:0915(physical association)
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
RPSA 3921 RAN 5901 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
ACTB 60 CAD 790 pp -- int.I2D: IntAct_Yeast
PSMB7 5695 RBX1 9978 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
HNRNPC 3183 RUVBL2 10856 pd < reg.ITFP.txt: no annot
ATP6V1B2 526 CDC16 8881 pp -- int.I2D: IntAct_Yeast
CDC16 8881 PTTG1 9232 pp -- int.I2D: BioGrid
PSMB1 5689 PSMB7 5695 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastLow, IntAct, Krogan_Core, MINT_Yeast, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
ACTB 60 RAN 5901 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, NON_CORE
CAD 790 RAN 5901 pp -- int.I2D: IntAct_Yeast
PSMB7 5695 TREX1 11277 pd < reg.ITFP.txt: no annot
ATP6V1B2 526 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
RPSA 3921 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
CAD 790 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
ATP6V1B2 526 RPSA 3921 pp -- int.I2D: IntAct_Yeast
ACTB 60 CDC16 8881 pp -- int.I2D: YeastLow
PSMD11 5717 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMB1 5689 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB1 5689 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 ATP6V1B2 526 pp -- int.I2D: BioGrid_Yeast
RAN 5901 TREX1 11277 pd < reg.ITFP.txt: no annot
RUVBL2 10856 TREX1 11277 pd <> reg.ITFP.txt: no annot
ACTB 60 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
CAD 790 RPSA 3921 pp -- int.I2D: IntAct_Yeast

Related GO terms (295)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process8.17e-111.33e-066.27662579
GO:0005654nucleoplasm3.77e-106.16e-063.35711831095
GO:0005829cytosol4.69e-107.65e-062.479141252562
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle3.62e-095.90e-056.29452465
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle5.28e-098.62e-056.18752470
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle7.02e-091.15e-046.10752474
GO:0000278mitotic cell cycle4.60e-087.51e-044.165752398
GO:0006521regulation of cellular amino acid metabolic process1.38e-072.25e-036.35142150
GO:0000082G1/S transition of mitotic cell cycle2.47e-074.03e-035.088533150
GO:0000502proteasome complex2.53e-074.13e-036.13642258
GO:0016032viral process3.68e-076.01e-033.725755540
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest4.02e-076.56e-035.97242265
GO:0005839proteasome core complex6.25e-071.02e-027.40931118
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent6.44e-071.05e-025.80542373
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I7.98e-071.30e-025.72842377
GO:0004298threonine-type endopeptidase activity8.72e-071.42e-027.25731120
GO:0010467gene expression1.56e-062.55e-023.416758669
GO:0016071mRNA metabolic process1.76e-062.87e-024.515534223
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.78e-062.91e-025.44042394
GO:0070062extracellular vesicular exosome2.35e-063.84e-022.15711982516
GO:0016070RNA metabolic process2.91e-064.74e-024.368534247
GO:0006281DNA repair4.03e-066.57e-024.272522264
GO:0000209protein polyubiquitination4.13e-066.74e-025.136421116
GO:0042981regulation of apoptotic process1.18e-051.92e-014.756426151
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding1.86e-053.04e-015.8253554
GO:0034641cellular nitrogen compound metabolic process2.20e-053.59e-014.527425177
GO:0035267NuA4 histone acetyltransferase complex8.14e-051.00e+007.1872414
GO:0016020membrane9.86e-051.00e+002.2258801746
GO:0006259DNA metabolic process1.53e-041.00e+006.7472319
GO:0006298mismatch repair1.69e-041.00e+006.6732620
GO:0043044ATP-dependent chromatin remodeling2.25e-041.00e+006.4712423
GO:0005634nucleus2.28e-041.00e+001.342121314828
GO:0031492nucleosomal DNA binding3.36e-041.00e+006.1872428
GO:0005515protein binding4.55e-041.00e+001.114131726127
GO:0043066negative regulation of apoptotic process6.90e-041.00e+003.236430433
GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity9.80e-041.00e+009.994111
GO:0070335aspartate binding9.80e-041.00e+009.994111
GO:0032558adenyl deoxyribonucleotide binding9.80e-041.00e+009.994111
GO:0004151dihydroorotase activity9.80e-041.00e+009.994111
GO:0004070aspartate carbamoyltransferase activity9.80e-041.00e+009.994111
GO:0044281small molecule metabolic process9.85e-041.00e+002.2416571295
GO:0003684damaged DNA binding1.12e-031.00e+005.32221151
GO:0007067mitotic nuclear division1.37e-031.00e+003.728313231
GO:0006310DNA recombination1.92e-031.00e+004.9282467
GO:0006915apoptotic process1.93e-031.00e+002.837434571
GO:0006407rRNA export from nucleus1.96e-031.00e+008.994112
GO:00082963'-5'-exodeoxyribonuclease activity1.96e-031.00e+008.994112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)1.96e-031.00e+008.994112
GO:0005055laminin receptor activity1.96e-031.00e+008.994112
GO:0070409carbamoyl phosphate biosynthetic process1.96e-031.00e+008.994112
GO:0003697single-stranded DNA binding2.03e-031.00e+004.8862969
GO:0043234protein complex2.88e-031.00e+003.351317300
GO:0071899negative regulation of estrogen receptor binding2.94e-031.00e+008.409113
GO:0071733transcriptional activation by promoter-enhancer looping2.94e-031.00e+008.409113
GO:0000056ribosomal small subunit export from nucleus2.94e-031.00e+008.409113
GO:0044205'de novo' UMP biosynthetic process2.94e-031.00e+008.409113
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process2.94e-031.00e+008.409113
GO:0016363nuclear matrix3.58e-031.00e+004.47121192
GO:0042470melanosome3.58e-031.00e+004.47121092
GO:0005730nucleolus3.84e-031.00e+001.8626701684
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)3.92e-031.00e+007.994114
GO:003068690S preribosome3.92e-031.00e+007.994114
GO:0019788NEDD8 ligase activity3.92e-031.00e+007.994114
GO:0043141ATP-dependent 5'-3' DNA helicase activity3.92e-031.00e+007.994114
GO:0006543glutamine catabolic process3.92e-031.00e+007.994114
GO:0031467Cul7-RING ubiquitin ligase complex3.92e-031.00e+007.994114
GO:0000055ribosomal large subunit export from nucleus3.92e-031.00e+007.994114
GO:0008853exodeoxyribonuclease III activity3.92e-031.00e+007.994114
GO:0051414response to cortisol4.89e-031.00e+007.673115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex4.89e-031.00e+007.673125
GO:0032407MutSalpha complex binding4.89e-031.00e+007.673115
GO:2000001regulation of DNA damage checkpoint4.89e-031.00e+007.673115
GO:0031461cullin-RING ubiquitin ligase complex4.89e-031.00e+007.673115
GO:0071169establishment of protein localization to chromatin4.89e-031.00e+007.673115
GO:0043248proteasome assembly4.89e-031.00e+007.673115
GO:0030891VCB complex4.89e-031.00e+007.673125
GO:0000730DNA recombinase assembly4.89e-031.00e+007.673135
GO:0030529ribonucleoprotein complex5.44e-031.00e+004.16228114
GO:0019058viral life cycle5.54e-031.00e+004.149210115
GO:0031466Cul5-RING ubiquitin ligase complex5.87e-031.00e+007.409116
GO:0030957Tat protein binding5.87e-031.00e+007.409146
GO:0046134pyrimidine nucleoside biosynthetic process5.87e-031.00e+007.409116
GO:0032405MutLalpha complex binding5.87e-031.00e+007.409126
GO:0006325chromatin organization6.31e-031.00e+004.05224123
GO:0006260DNA replication6.51e-031.00e+004.029212125
GO:0000028ribosomal small subunit assembly6.84e-031.00e+007.187117
GO:0031462Cul2-RING ubiquitin ligase complex6.84e-031.00e+007.187127
GO:0033180proton-transporting V-type ATPase, V1 domain6.84e-031.00e+007.187127
GO:0000790nuclear chromatin7.34e-031.00e+003.93927133
GO:0031464Cul4A-RING E3 ubiquitin ligase complex7.82e-031.00e+006.994128
GO:0070688MLL5-L complex7.82e-031.00e+006.994118
GO:0000812Swr1 complex7.82e-031.00e+006.994138
GO:0045116protein neddylation7.82e-031.00e+006.994128
GO:0014075response to amine8.79e-031.00e+006.825119
GO:0006228UTP biosynthetic process8.79e-031.00e+006.825119
GO:0031000response to caffeine8.79e-031.00e+006.825129
GO:0006457protein folding9.14e-031.00e+003.77528149
GO:0010569regulation of double-strand break repair via homologous recombination1.07e-021.00e+006.5351111
GO:0031571mitotic G1 DNA damage checkpoint1.07e-021.00e+006.5351311
GO:0045120pronucleus1.07e-021.00e+006.5351111
GO:0035458cellular response to interferon-beta1.07e-021.00e+006.5351211
GO:0042802identical protein binding1.13e-021.00e+002.640318491
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding1.15e-021.00e+003.60225168
GO:00709353'-UTR-mediated mRNA stabilization1.17e-021.00e+006.4091212
GO:0043968histone H2A acetylation1.17e-021.00e+006.4091312
GO:0005838proteasome regulatory particle1.17e-021.00e+006.4091712
GO:0032479regulation of type I interferon production1.27e-021.00e+006.2941213
GO:0005662DNA replication factor A complex1.27e-021.00e+006.2941313
GO:0000738DNA catabolic process, exonucleolytic1.27e-021.00e+006.2941213
GO:0008266poly(U) RNA binding1.27e-021.00e+006.2941113
GO:0031625ubiquitin protein ligase binding1.31e-021.00e+003.503213180
GO:0031011Ino80 complex1.36e-021.00e+006.1871314
GO:0035066positive regulation of histone acetylation1.46e-021.00e+006.0881115
GO:0046961proton-transporting ATPase activity, rotational mechanism1.46e-021.00e+006.0881315
GO:0046034ATP metabolic process1.56e-021.00e+005.9941116
GO:0050998nitric-oxide synthase binding1.56e-021.00e+005.9941116
GO:0051276chromosome organization1.56e-021.00e+005.9941416
GO:00084083'-5' exonuclease activity1.56e-021.00e+005.9941216
GO:0010243response to organonitrogen compound1.65e-021.00e+005.9071217
GO:0075733intracellular transport of virus1.65e-021.00e+005.9071217
GO:0022624proteasome accessory complex1.65e-021.00e+005.9071917
GO:0071392cellular response to estradiol stimulus1.75e-021.00e+005.8251118
GO:0006541glutamine metabolic process1.75e-021.00e+005.8251118
GO:0035861site of double-strand break1.75e-021.00e+005.8251118
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process1.85e-021.00e+005.7471119
GO:0048863stem cell differentiation1.85e-021.00e+005.7471119
GO:0007088regulation of mitosis1.85e-021.00e+005.7471119
GO:0003678DNA helicase activity1.85e-021.00e+005.7471319
GO:0015078hydrogen ion transmembrane transporter activity1.94e-021.00e+005.6731320
GO:0005680anaphase-promoting complex1.94e-021.00e+005.6731420
GO:0005719nuclear euchromatin1.94e-021.00e+005.6731220
GO:0000718nucleotide-excision repair, DNA damage removal2.04e-021.00e+005.6021521
GO:0071364cellular response to epidermal growth factor stimulus2.04e-021.00e+005.6021121
GO:0006297nucleotide-excision repair, DNA gap filling2.14e-021.00e+005.5351522
GO:0033574response to testosterone2.14e-021.00e+005.5351222
GO:0032201telomere maintenance via semi-conservative replication2.14e-021.00e+005.5351722
GO:0030863cortical cytoskeleton2.14e-021.00e+005.5351122
GO:0036464cytoplasmic ribonucleoprotein granule2.14e-021.00e+005.5351422
GO:0007052mitotic spindle organization2.14e-021.00e+005.5351222
GO:0031463Cul3-RING ubiquitin ligase complex2.23e-021.00e+005.4711223
GO:0043236laminin binding2.23e-021.00e+005.4711123
GO:0006513protein monoubiquitination2.23e-021.00e+005.4711123
GO:0006206pyrimidine nucleobase metabolic process2.33e-021.00e+005.4091224
GO:0006611protein export from nucleus2.42e-021.00e+005.3511425
GO:0017144drug metabolic process2.42e-021.00e+005.3511125
GO:0070979protein K11-linked ubiquitination2.52e-021.00e+005.2941326
GO:0000722telomere maintenance via recombination2.52e-021.00e+005.2941726
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia2.52e-021.00e+005.2941226
GO:0004003ATP-dependent DNA helicase activity2.62e-021.00e+005.2401327
GO:0071339MLL1 complex2.62e-021.00e+005.2401327
GO:0004869cysteine-type endopeptidase inhibitor activity2.62e-021.00e+005.2401127
GO:0015991ATP hydrolysis coupled proton transport2.71e-021.00e+005.1871428
GO:0043022ribosome binding2.71e-021.00e+005.1871328
GO:0043967histone H4 acetylation2.71e-021.00e+005.1871328
GO:0019894kinesin binding2.71e-021.00e+005.1871128
GO:0019005SCF ubiquitin ligase complex2.81e-021.00e+005.1361129
GO:0003730mRNA 3'-UTR binding2.81e-021.00e+005.1361229
GO:0006271DNA strand elongation involved in DNA replication3.00e-021.00e+005.0401931
GO:0007094mitotic spindle assembly checkpoint3.00e-021.00e+005.0401531
GO:0015992proton transport3.09e-021.00e+004.9941332
GO:0034644cellular response to UV3.09e-021.00e+004.9941532
GO:0033572transferrin transport3.09e-021.00e+004.9941632
GO:0019899enzyme binding3.16e-021.00e+002.825211288
GO:0051701interaction with host3.28e-021.00e+004.9071434
GO:0005876spindle microtubule3.28e-021.00e+004.9071334
GO:0034332adherens junction organization3.47e-021.00e+004.8251136
GO:0001895retina homeostasis3.47e-021.00e+004.8251136
GO:0051084'de novo' posttranslational protein folding3.57e-021.00e+004.7851437
GO:0018107peptidyl-threonine phosphorylation3.57e-021.00e+004.7851137
GO:0070527platelet aggregation3.66e-021.00e+004.7471238
GO:0050681androgen receptor binding3.66e-021.00e+004.7471438
GO:0090382phagosome maturation3.66e-021.00e+004.7471538
GO:0031490chromatin DNA binding3.76e-021.00e+004.7091239
GO:0006284base-excision repair3.76e-021.00e+004.7091739
GO:0022627cytosolic small ribosomal subunit3.76e-021.00e+004.7091339
GO:0032092positive regulation of protein binding3.76e-021.00e+004.7091339
GO:0007595lactation3.76e-021.00e+004.7091239
GO:0005524ATP binding3.83e-021.00e+001.5914461354
GO:0000781chromosome, telomeric region3.85e-021.00e+004.6731240
GO:0043195terminal bouton3.95e-021.00e+004.6371141
GO:0030521androgen receptor signaling pathway3.95e-021.00e+004.6371241
GO:0005902microvillus4.04e-021.00e+004.6021242
GO:0032508DNA duplex unwinding4.04e-021.00e+004.6021442
GO:0014070response to organic cyclic compound4.14e-021.00e+004.5681343
GO:0007286spermatid development4.23e-021.00e+004.5351144
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding4.23e-021.00e+004.5351244
GO:0021762substantia nigra development4.42e-021.00e+004.4711146
GO:0006283transcription-coupled nucleotide-excision repair4.42e-021.00e+004.4711846
GO:0019003GDP binding4.61e-021.00e+004.4091248
GO:0031100organ regeneration4.79e-021.00e+004.3511450
GO:0035690cellular response to drug4.79e-021.00e+004.3511250
GO:0040008regulation of growth4.89e-021.00e+004.3221351
GO:0090305nucleic acid phosphodiester bond hydrolysis5.17e-021.00e+004.2401254
GO:0006879cellular iron ion homeostasis5.45e-021.00e+004.1621557
GO:0000724double-strand break repair via homologous recombination5.45e-021.00e+004.1621657
GO:0012505endomembrane system5.45e-021.00e+004.1621257
GO:0045216cell-cell junction organization5.63e-021.00e+004.1121259
GO:0000723telomere maintenance5.63e-021.00e+004.1121859
GO:0005643nuclear pore5.63e-021.00e+004.1121459
GO:0032481positive regulation of type I interferon production5.82e-021.00e+004.0641661
GO:0006302double-strand break repair5.91e-021.00e+004.0401862
GO:0019903protein phosphatase binding6.00e-021.00e+004.0171463
GO:0042995cell projection6.00e-021.00e+004.0171663
GO:0007059chromosome segregation6.10e-021.00e+003.9941364
GO:0006338chromatin remodeling6.46e-021.00e+003.9071468
GO:0006289nucleotide-excision repair6.56e-021.00e+003.88611269
GO:0034329cell junction assembly6.74e-021.00e+003.8451171
GO:0000785chromatin6.92e-021.00e+003.8051573
GO:0055086nucleobase-containing small molecule metabolic process6.92e-021.00e+003.8051573
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process7.20e-021.00e+003.7471376
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis7.29e-021.00e+003.7281577
GO:0071013catalytic step 2 spliceosome7.47e-021.00e+003.6911779
GO:0007565female pregnancy7.56e-021.00e+003.6731280
GO:0019083viral transcription7.66e-021.00e+003.6551881
GO:0001889liver development7.75e-021.00e+003.6371382
GO:0001726ruffle7.75e-021.00e+003.6371482
GO:0005681spliceosomal complex7.84e-021.00e+003.6191383
GO:0047485protein N-terminus binding8.11e-021.00e+003.5681486
GO:0006415translational termination8.20e-021.00e+003.5511887
GO:0044267cellular protein metabolic process8.33e-021.00e+002.043224495
GO:0044822poly(A) RNA binding8.45e-021.00e+001.5053501078
GO:0003690double-stranded DNA binding8.56e-021.00e+003.4871491
GO:0016605PML body8.65e-021.00e+003.4711592
GO:0006928cellular component movement8.65e-021.00e+003.4711792
GO:0006414translational elongation8.74e-021.00e+003.45511193
GO:0005200structural constituent of cytoskeleton8.74e-021.00e+003.4551793
GO:0051082unfolded protein binding8.92e-021.00e+003.4251695
GO:0001649osteoblast differentiation8.92e-021.00e+003.4251695
GO:0071456cellular response to hypoxia9.19e-021.00e+003.3801498
GO:0006614SRP-dependent cotranslational protein targeting to membrane9.73e-021.00e+003.29418104
GO:0014069postsynaptic density9.90e-021.00e+003.26711106
GO:0015630microtubule cytoskeleton1.04e-011.00e+003.18715112
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.06e-011.00e+003.162110114
GO:0010951negative regulation of endopeptidase activity1.06e-011.00e+003.16211114
GO:0005819spindle1.06e-011.00e+003.16217114
GO:0017124SH3 domain binding1.07e-011.00e+003.14913115
GO:0005635nuclear envelope1.08e-011.00e+003.13616116
GO:0072562blood microparticle1.08e-011.00e+003.13614116
GO:0007219Notch signaling pathway1.16e-011.00e+003.02914125
GO:0006511ubiquitin-dependent protein catabolic process1.18e-011.00e+003.00615127
GO:0006413translational initiation1.21e-011.00e+002.961112131
GO:0045087innate immune response1.21e-011.00e+001.728220616
GO:0003735structural constituent of ribosome1.30e-011.00e+002.85518141
GO:0007507heart development1.30e-011.00e+002.85515141
GO:0008286insulin receptor signaling pathway1.32e-011.00e+002.82516144
GO:0016887ATPase activity1.32e-011.00e+002.82517144
GO:0061024membrane organization1.34e-011.00e+002.80515146
GO:0046777protein autophosphorylation1.44e-011.00e+002.69113158
GO:0000398mRNA splicing, via spliceosome1.50e-011.00e+002.628112165
GO:0030424axon1.56e-011.00e+002.56813172
GO:0004672protein kinase activity1.61e-011.00e+002.51912178
GO:0019904protein domain specific binding1.63e-011.00e+002.49516181
GO:0032403protein complex binding1.67e-011.00e+002.46317185
GO:0005737cytoplasm1.73e-011.00e+000.6226983976
GO:0003924GTPase activity1.82e-011.00e+002.32919203
GO:0005765lysosomal membrane1.94e-011.00e+002.22615218
GO:0006184GTP catabolic process1.95e-011.00e+002.21319220
GO:0005622intracellular2.00e-011.00e+002.17415226
GO:0008380RNA splicing2.05e-011.00e+002.136113232
GO:0006412translation2.07e-011.00e+002.118115235
GO:0003713transcription coactivator activity2.10e-011.00e+002.094110239
GO:0043025neuronal cell body2.22e-011.00e+002.00614254
GO:0004842ubiquitin-protein transferase activity2.24e-011.00e+001.99414256
GO:0000166nucleotide binding2.36e-011.00e+001.90716272
GO:0007283spermatogenesis2.39e-011.00e+001.88616276
GO:0007264small GTPase mediated signal transduction2.49e-011.00e+001.81513290
GO:0016567protein ubiquitination2.56e-011.00e+001.77015299
GO:0006200ATP catabolic process2.59e-011.00e+001.751114303
GO:0005856cytoskeleton2.65e-011.00e+001.71418311
GO:0019901protein kinase binding2.72e-011.00e+001.673121320
GO:0007411axon guidance2.77e-011.00e+001.64119327
GO:0005525GTP binding2.77e-011.00e+001.637111328
GO:0008283cell proliferation2.80e-011.00e+001.624112331
GO:0043231intracellular membrane-bounded organelle2.80e-011.00e+001.61918332
GO:0008270zinc ion binding2.82e-011.00e+000.9352121067
GO:0003682chromatin binding2.82e-011.00e+001.611112334
GO:0005813centrosome2.85e-011.00e+001.589112339
GO:0003723RNA binding2.97e-011.00e+001.523119355
GO:0005925focal adhesion3.07e-011.00e+001.463118370
GO:0007155cell adhesion3.17e-011.00e+001.40918384
GO:0006366transcription from RNA polymerase II promoter3.45e-011.00e+001.263112425
GO:0007596blood coagulation3.70e-011.00e+001.136114464
GO:0045893positive regulation of transcription, DNA-templated3.84e-011.00e+001.067117487
GO:0055085transmembrane transport4.01e-011.00e+000.98918514
GO:0042803protein homodimerization activity4.60e-011.00e+000.725111617
GO:0005789endoplasmic reticulum membrane4.71e-011.00e+000.682110636
GO:0003700sequence-specific DNA binding transcription factor activity5.28e-011.00e+000.448111748
GO:0045944positive regulation of transcription from RNA polymerase II promoter5.58e-011.00e+000.331119811
GO:0007165signal transduction6.17e-011.00e+000.103117950
GO:0005615extracellular space6.40e-011.00e+000.0141171010
GO:0006355regulation of transcription, DNA-templated6.74e-011.00e+00-0.1141171104
GO:0046872metal ion binding7.78e-011.00e+00-0.5221241465
GO:0005886plasma membrane7.94e-011.00e+00-0.4742382834
GO:0006351transcription, DNA-templated8.05e-011.00e+00-0.6361251585
GO:0016021integral component of membrane9.29e-011.00e+00-1.2831152483