Subnetwork | Dataset | Score | p-value 1 | p-value 2 | p-value 3 | Size | Highlighted genes |
---|---|---|---|---|---|---|---|
reg-snw-317781 | wolf-screen-ratio-mammosphere-adherent | 0.823 | 1.13e-06 | 3.23e-03 | 6.07e-03 | 9 | 9 |
int-snw-8453 | wolf-screen-ratio-mammosphere-adherent | 0.955 | 2.74e-16 | 1.60e-03 | 2.91e-02 | 9 | 8 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
RPA2 | 6118 | 96 | 1.250 | 1.151 | 76 | Yes | - |
EIF6 | 3692 | 67 | 0.700 | 0.876 | 316 | Yes | - |
KEAP1 | 9817 | 2 | 0.580 | 0.981 | 63 | Yes | - |
RBX1 | 9978 | 115 | 1.185 | 0.934 | 148 | Yes | - |
PSMD3 | 5709 | 100 | 0.986 | 1.106 | 201 | Yes | - |
CUL2 | 8453 | 2 | 0.020 | 0.955 | 64 | - | - |
PSMB7 | 5695 | 118 | 0.982 | 0.934 | 90 | Yes | - |
TUBG1 | 7283 | 98 | 0.974 | 0.973 | 91 | Yes | - |
PSMB2 | 5690 | 116 | 0.877 | 0.956 | 169 | Yes | - |
PSMA1 | 5682 | 100 | 0.996 | 0.878 | 152 | Yes | - |
PSMD11 | 5717 | 124 | 1.095 | 1.106 | 218 | Yes | - |
ACTB | 60 | 134 | 1.153 | 1.151 | 610 | Yes | - |
VARS | 7407 | 86 | 0.549 | 1.002 | 204 | Yes | - |
DDX51 | 317781 | 53 | 0.059 | 0.823 | 210 | Yes | - |
RPSA | 3921 | 120 | 1.327 | 1.151 | 152 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
PSMA1 | 5682 | PSMB2 | 5690 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
CUL2 | 8453 | RBX1 | 9978 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct, IntAct_Worm, MINT; int.Mint: MI:0915(physical association), MI:0914(association) |
RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | PSMB2 | 5690 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
RPSA | 3921 | VARS | 7407 | pp | -- | int.I2D: IntAct_Yeast |
PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
TUBG1 | 7283 | VARS | 7407 | pd | < | reg.ITFP.txt: no annot |
PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast |
ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB7 | 5695 | RBX1 | 9978 | pd | < | reg.ITFP.txt: no annot |
PSMD3 | 5709 | TUBG1 | 7283 | pd | > | reg.ITFP.txt: no annot |
PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB7 | 5695 | DDX51 | 317781 | pd | < | reg.ITFP.txt: no annot |
PSMB2 | 5690 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct |
CUL2 | 8453 | KEAP1 | 9817 | pp | -- | int.I2D: BioGrid |
PSMB2 | 5690 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
VARS | 7407 | DDX51 | 317781 | pd | <> | reg.ITFP.txt: no annot |
PSMD3 | 5709 | VARS | 7407 | pd | <> | reg.ITFP.txt: no annot |
PSMD11 | 5717 | TUBG1 | 7283 | pd | > | reg.ITFP.txt: no annot |
ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | RPA2 | 6118 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
PSMB2 | 5690 | DDX51 | 317781 | pd | < | reg.ITFP.txt: no annot |
PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMB2 | 5690 | PSMD11 | 5717 | pd | < | reg.ITFP.txt: no annot |
PSMB2 | 5690 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
KEAP1 | 9817 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid, BioGrid_Mouse |
PSMB2 | 5690 | VARS | 7407 | pd | < | reg.ITFP.txt: no annot |
EIF6 | 3692 | DDX51 | 317781 | pd | < | reg.ITFP.txt: no annot |
PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0000082 | G1/S transition of mitotic cell cycle | 2.91e-11 | 4.75e-07 | 5.666 | 7 | 33 | 150 |
GO:0006521 | regulation of cellular amino acid metabolic process | 6.45e-10 | 1.05e-05 | 6.766 | 5 | 21 | 50 |
GO:0000502 | proteasome complex | 1.39e-09 | 2.27e-05 | 6.551 | 5 | 22 | 58 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 2.49e-09 | 4.07e-05 | 6.387 | 5 | 24 | 65 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 2.49e-09 | 4.07e-05 | 6.387 | 5 | 22 | 65 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 3.65e-09 | 5.95e-05 | 6.280 | 5 | 24 | 70 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 4.52e-09 | 7.37e-05 | 6.220 | 5 | 23 | 73 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 4.84e-09 | 7.90e-05 | 6.200 | 5 | 24 | 74 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 5.93e-09 | 9.68e-05 | 6.143 | 5 | 23 | 77 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 6.76e-09 | 1.10e-04 | 6.106 | 5 | 25 | 79 |
GO:0016032 | viral process | 7.15e-09 | 1.17e-04 | 4.011 | 8 | 55 | 540 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 1.63e-08 | 2.67e-04 | 5.855 | 5 | 23 | 94 |
GO:0000278 | mitotic cell cycle | 2.65e-08 | 4.32e-04 | 4.258 | 7 | 52 | 398 |
GO:0016071 | mRNA metabolic process | 2.75e-08 | 4.48e-04 | 4.872 | 6 | 34 | 223 |
GO:0000209 | protein polyubiquitination | 4.72e-08 | 7.70e-04 | 5.551 | 5 | 21 | 116 |
GO:0016070 | RNA metabolic process | 5.05e-08 | 8.24e-04 | 4.724 | 6 | 34 | 247 |
GO:0005829 | cytosol | 6.25e-08 | 1.02e-03 | 2.349 | 12 | 125 | 2562 |
GO:0005654 | nucleoplasm | 9.23e-08 | 1.51e-03 | 3.161 | 9 | 83 | 1095 |
GO:0042981 | regulation of apoptotic process | 1.77e-07 | 2.89e-03 | 5.171 | 5 | 26 | 151 |
GO:0034641 | cellular nitrogen compound metabolic process | 3.90e-07 | 6.36e-03 | 4.942 | 5 | 25 | 177 |
GO:0005839 | proteasome core complex | 5.08e-07 | 8.30e-03 | 7.503 | 3 | 11 | 18 |
GO:0004298 | threonine-type endopeptidase activity | 7.09e-07 | 1.16e-02 | 7.351 | 3 | 11 | 20 |
GO:0010467 | gene expression | 9.10e-07 | 1.48e-02 | 3.509 | 7 | 58 | 669 |
GO:0005730 | nucleolus | 3.64e-06 | 5.94e-02 | 2.540 | 9 | 70 | 1684 |
GO:0030891 | VCB complex | 7.87e-06 | 1.28e-01 | 8.766 | 2 | 2 | 5 |
GO:0031462 | Cul2-RING ubiquitin ligase complex | 1.65e-05 | 2.70e-01 | 8.280 | 2 | 2 | 7 |
GO:0043066 | negative regulation of apoptotic process | 3.10e-05 | 5.05e-01 | 3.651 | 5 | 30 | 433 |
GO:0005838 | proteasome regulatory particle | 5.18e-05 | 8.45e-01 | 7.503 | 2 | 7 | 12 |
GO:0022624 | proteasome accessory complex | 1.06e-04 | 1.00e+00 | 7.000 | 2 | 9 | 17 |
GO:0006915 | apoptotic process | 1.16e-04 | 1.00e+00 | 3.252 | 5 | 34 | 571 |
GO:0031463 | Cul3-RING ubiquitin ligase complex | 1.97e-04 | 1.00e+00 | 6.564 | 2 | 2 | 23 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 2.53e-04 | 1.00e+00 | 6.387 | 2 | 2 | 26 |
GO:0043022 | ribosome binding | 2.94e-04 | 1.00e+00 | 6.280 | 2 | 3 | 28 |
GO:0031625 | ubiquitin protein ligase binding | 5.44e-04 | 1.00e+00 | 4.181 | 3 | 13 | 180 |
GO:0070062 | extracellular vesicular exosome | 7.32e-04 | 1.00e+00 | 1.791 | 8 | 98 | 2516 |
GO:0000054 | ribosomal subunit export from nucleus | 9.19e-04 | 1.00e+00 | 10.088 | 1 | 1 | 1 |
GO:0005515 | protein binding | 9.95e-04 | 1.00e+00 | 1.092 | 12 | 172 | 6127 |
GO:0004832 | valine-tRNA ligase activity | 1.84e-03 | 1.00e+00 | 9.088 | 1 | 1 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 1.84e-03 | 1.00e+00 | 9.088 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 1.84e-03 | 1.00e+00 | 9.088 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 1.84e-03 | 1.00e+00 | 9.088 | 1 | 1 | 2 |
GO:0006438 | valyl-tRNA aminoacylation | 1.84e-03 | 1.00e+00 | 9.088 | 1 | 1 | 2 |
GO:0016567 | protein ubiquitination | 2.35e-03 | 1.00e+00 | 3.449 | 3 | 5 | 299 |
GO:0045604 | regulation of epidermal cell differentiation | 2.75e-03 | 1.00e+00 | 8.503 | 1 | 1 | 3 |
GO:0016020 | membrane | 3.17e-03 | 1.00e+00 | 1.903 | 6 | 80 | 1746 |
GO:0005200 | structural constituent of cytoskeleton | 3.21e-03 | 1.00e+00 | 4.548 | 2 | 7 | 93 |
GO:0005634 | nucleus | 3.24e-03 | 1.00e+00 | 1.172 | 10 | 131 | 4828 |
GO:0071456 | cellular response to hypoxia | 3.56e-03 | 1.00e+00 | 4.473 | 2 | 4 | 98 |
GO:0010499 | proteasomal ubiquitin-independent protein catabolic process | 3.67e-03 | 1.00e+00 | 8.088 | 1 | 1 | 4 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 3.67e-03 | 1.00e+00 | 8.088 | 1 | 1 | 4 |
GO:0000212 | meiotic spindle organization | 3.67e-03 | 1.00e+00 | 8.088 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 3.67e-03 | 1.00e+00 | 8.088 | 1 | 1 | 4 |
GO:0031467 | Cul7-RING ubiquitin ligase complex | 3.67e-03 | 1.00e+00 | 8.088 | 1 | 1 | 4 |
GO:0019788 | NEDD8 ligase activity | 3.67e-03 | 1.00e+00 | 8.088 | 1 | 1 | 4 |
GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 2 | 5 |
GO:0031461 | cullin-RING ubiquitin ligase complex | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 1 | 5 |
GO:0042256 | mature ribosome assembly | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 1 | 5 |
GO:0043248 | proteasome assembly | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 1 | 5 |
GO:0005827 | polar microtubule | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 1 | 5 |
GO:0000730 | DNA recombinase assembly | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 3 | 5 |
GO:2000001 | regulation of DNA damage checkpoint | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 1 | 5 |
GO:0005638 | lamin filament | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 1 | 5 |
GO:0044281 | small molecule metabolic process | 4.77e-03 | 1.00e+00 | 2.071 | 5 | 57 | 1295 |
GO:0030957 | Tat protein binding | 5.50e-03 | 1.00e+00 | 7.503 | 1 | 4 | 6 |
GO:0043023 | ribosomal large subunit binding | 5.50e-03 | 1.00e+00 | 7.503 | 1 | 2 | 6 |
GO:0031466 | Cul5-RING ubiquitin ligase complex | 5.50e-03 | 1.00e+00 | 7.503 | 1 | 1 | 6 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 5.90e-03 | 1.00e+00 | 4.099 | 2 | 5 | 127 |
GO:0006413 | translational initiation | 6.27e-03 | 1.00e+00 | 4.054 | 2 | 12 | 131 |
GO:0000028 | ribosomal small subunit assembly | 6.42e-03 | 1.00e+00 | 7.280 | 1 | 1 | 7 |
GO:0002161 | aminoacyl-tRNA editing activity | 6.42e-03 | 1.00e+00 | 7.280 | 1 | 2 | 7 |
GO:0000930 | gamma-tubulin complex | 6.42e-03 | 1.00e+00 | 7.280 | 1 | 1 | 7 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 7.33e-03 | 1.00e+00 | 7.088 | 1 | 5 | 8 |
GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 7.33e-03 | 1.00e+00 | 7.088 | 1 | 2 | 8 |
GO:0070688 | MLL5-L complex | 7.33e-03 | 1.00e+00 | 7.088 | 1 | 1 | 8 |
GO:0045116 | protein neddylation | 7.33e-03 | 1.00e+00 | 7.088 | 1 | 2 | 8 |
GO:0006450 | regulation of translational fidelity | 9.16e-03 | 1.00e+00 | 6.766 | 1 | 2 | 10 |
GO:0010569 | regulation of double-strand break repair via homologous recombination | 1.01e-02 | 1.00e+00 | 6.628 | 1 | 1 | 11 |
GO:0031571 | mitotic G1 DNA damage checkpoint | 1.01e-02 | 1.00e+00 | 6.628 | 1 | 3 | 11 |
GO:0042273 | ribosomal large subunit biogenesis | 1.19e-02 | 1.00e+00 | 6.387 | 1 | 4 | 13 |
GO:0005662 | DNA replication factor A complex | 1.19e-02 | 1.00e+00 | 6.387 | 1 | 3 | 13 |
GO:0030234 | enzyme regulator activity | 1.19e-02 | 1.00e+00 | 6.387 | 1 | 3 | 13 |
GO:0032403 | protein complex binding | 1.22e-02 | 1.00e+00 | 3.556 | 2 | 7 | 185 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.28e-02 | 1.00e+00 | 6.280 | 1 | 4 | 14 |
GO:0007020 | microtubule nucleation | 1.28e-02 | 1.00e+00 | 6.280 | 1 | 1 | 14 |
GO:0050998 | nitric-oxide synthase binding | 1.46e-02 | 1.00e+00 | 6.088 | 1 | 1 | 16 |
GO:0042176 | regulation of protein catabolic process | 1.46e-02 | 1.00e+00 | 6.088 | 1 | 3 | 16 |
GO:0010243 | response to organonitrogen compound | 1.55e-02 | 1.00e+00 | 6.000 | 1 | 2 | 17 |
GO:0031122 | cytoplasmic microtubule organization | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 2 | 18 |
GO:0035861 | site of double-strand break | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 18 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.73e-02 | 1.00e+00 | 5.840 | 1 | 1 | 19 |
GO:0048863 | stem cell differentiation | 1.73e-02 | 1.00e+00 | 5.840 | 1 | 1 | 19 |
GO:0071353 | cellular response to interleukin-4 | 1.82e-02 | 1.00e+00 | 5.766 | 1 | 1 | 20 |
GO:0006298 | mismatch repair | 1.82e-02 | 1.00e+00 | 5.766 | 1 | 6 | 20 |
GO:0000718 | nucleotide-excision repair, DNA damage removal | 1.91e-02 | 1.00e+00 | 5.695 | 1 | 5 | 21 |
GO:0006297 | nucleotide-excision repair, DNA gap filling | 2.00e-02 | 1.00e+00 | 5.628 | 1 | 5 | 22 |
GO:0032201 | telomere maintenance via semi-conservative replication | 2.00e-02 | 1.00e+00 | 5.628 | 1 | 7 | 22 |
GO:0030863 | cortical cytoskeleton | 2.00e-02 | 1.00e+00 | 5.628 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 2.00e-02 | 1.00e+00 | 5.628 | 1 | 4 | 22 |
GO:0043044 | ATP-dependent chromatin remodeling | 2.09e-02 | 1.00e+00 | 5.564 | 1 | 4 | 23 |
GO:0043236 | laminin binding | 2.09e-02 | 1.00e+00 | 5.564 | 1 | 1 | 23 |
GO:0006513 | protein monoubiquitination | 2.09e-02 | 1.00e+00 | 5.564 | 1 | 1 | 23 |
GO:0000794 | condensed nuclear chromosome | 2.18e-02 | 1.00e+00 | 5.503 | 1 | 2 | 24 |
GO:0005844 | polysome | 2.27e-02 | 1.00e+00 | 5.444 | 1 | 4 | 25 |
GO:0000722 | telomere maintenance via recombination | 2.36e-02 | 1.00e+00 | 5.387 | 1 | 7 | 26 |
GO:0006281 | DNA repair | 2.38e-02 | 1.00e+00 | 3.043 | 2 | 22 | 264 |
GO:0031492 | nucleosomal DNA binding | 2.54e-02 | 1.00e+00 | 5.280 | 1 | 4 | 28 |
GO:0019894 | kinesin binding | 2.54e-02 | 1.00e+00 | 5.280 | 1 | 1 | 28 |
GO:0019005 | SCF ubiquitin ligase complex | 2.63e-02 | 1.00e+00 | 5.230 | 1 | 1 | 29 |
GO:0006271 | DNA strand elongation involved in DNA replication | 2.81e-02 | 1.00e+00 | 5.133 | 1 | 9 | 31 |
GO:0034332 | adherens junction organization | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 1 | 36 |
GO:0001895 | retina homeostasis | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 1 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 3.35e-02 | 1.00e+00 | 4.878 | 1 | 4 | 37 |
GO:0070527 | platelet aggregation | 3.44e-02 | 1.00e+00 | 4.840 | 1 | 2 | 38 |
GO:0022627 | cytosolic small ribosomal subunit | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 3 | 39 |
GO:0008026 | ATP-dependent helicase activity | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 3 | 39 |
GO:0006284 | base-excision repair | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 7 | 39 |
GO:0000781 | chromosome, telomeric region | 3.62e-02 | 1.00e+00 | 4.766 | 1 | 2 | 40 |
GO:0005813 | centrosome | 3.78e-02 | 1.00e+00 | 2.682 | 2 | 12 | 339 |
GO:0006418 | tRNA aminoacylation for protein translation | 3.79e-02 | 1.00e+00 | 4.695 | 1 | 5 | 42 |
GO:0014070 | response to organic cyclic compound | 3.88e-02 | 1.00e+00 | 4.661 | 1 | 3 | 43 |
GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | 3.97e-02 | 1.00e+00 | 4.628 | 1 | 3 | 44 |
GO:0021762 | substantia nigra development | 4.15e-02 | 1.00e+00 | 4.564 | 1 | 1 | 46 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 4.15e-02 | 1.00e+00 | 4.564 | 1 | 8 | 46 |
GO:0003743 | translation initiation factor activity | 4.41e-02 | 1.00e+00 | 4.473 | 1 | 4 | 49 |
GO:0003684 | damaged DNA binding | 4.59e-02 | 1.00e+00 | 4.415 | 1 | 11 | 51 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 4.85e-02 | 1.00e+00 | 4.333 | 1 | 5 | 54 |
GO:0000226 | microtubule cytoskeleton organization | 4.94e-02 | 1.00e+00 | 4.306 | 1 | 3 | 55 |
GO:0097193 | intrinsic apoptotic signaling pathway | 4.94e-02 | 1.00e+00 | 4.306 | 1 | 4 | 55 |
GO:0000724 | double-strand break repair via homologous recombination | 5.11e-02 | 1.00e+00 | 4.255 | 1 | 6 | 57 |
GO:0000723 | telomere maintenance | 5.29e-02 | 1.00e+00 | 4.205 | 1 | 8 | 59 |
GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity | 5.29e-02 | 1.00e+00 | 4.205 | 1 | 4 | 59 |
GO:0045216 | cell-cell junction organization | 5.29e-02 | 1.00e+00 | 4.205 | 1 | 2 | 59 |
GO:0006302 | double-strand break repair | 5.55e-02 | 1.00e+00 | 4.133 | 1 | 8 | 62 |
GO:0019903 | protein phosphatase binding | 5.64e-02 | 1.00e+00 | 4.110 | 1 | 4 | 63 |
GO:0006289 | nucleotide-excision repair | 6.16e-02 | 1.00e+00 | 3.979 | 1 | 12 | 69 |
GO:0003697 | single-stranded DNA binding | 6.16e-02 | 1.00e+00 | 3.979 | 1 | 9 | 69 |
GO:0034329 | cell junction assembly | 6.33e-02 | 1.00e+00 | 3.938 | 1 | 1 | 71 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 6.76e-02 | 1.00e+00 | 3.840 | 1 | 3 | 76 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 6.85e-02 | 1.00e+00 | 3.821 | 1 | 5 | 77 |
GO:0019083 | viral transcription | 7.19e-02 | 1.00e+00 | 3.748 | 1 | 8 | 81 |
GO:0044267 | cellular protein metabolic process | 7.43e-02 | 1.00e+00 | 2.136 | 2 | 24 | 495 |
GO:0047485 | protein N-terminus binding | 7.62e-02 | 1.00e+00 | 3.661 | 1 | 4 | 86 |
GO:0006415 | translational termination | 7.71e-02 | 1.00e+00 | 3.645 | 1 | 8 | 87 |
GO:0016605 | PML body | 8.13e-02 | 1.00e+00 | 3.564 | 1 | 5 | 92 |
GO:0006928 | cellular component movement | 8.13e-02 | 1.00e+00 | 3.564 | 1 | 7 | 92 |
GO:0006414 | translational elongation | 8.22e-02 | 1.00e+00 | 3.548 | 1 | 11 | 93 |
GO:0006364 | rRNA processing | 8.47e-02 | 1.00e+00 | 3.503 | 1 | 5 | 96 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 9.15e-02 | 1.00e+00 | 3.387 | 1 | 8 | 104 |
GO:0014069 | postsynaptic density | 9.32e-02 | 1.00e+00 | 3.360 | 1 | 1 | 106 |
GO:0030496 | midbody | 9.57e-02 | 1.00e+00 | 3.319 | 1 | 4 | 109 |
GO:0005815 | microtubule organizing center | 9.65e-02 | 1.00e+00 | 3.306 | 1 | 4 | 110 |
GO:0015630 | microtubule cytoskeleton | 9.82e-02 | 1.00e+00 | 3.280 | 1 | 5 | 112 |
GO:0030529 | ribonucleoprotein complex | 9.98e-02 | 1.00e+00 | 3.255 | 1 | 8 | 114 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 9.98e-02 | 1.00e+00 | 3.255 | 1 | 10 | 114 |
GO:0019058 | viral life cycle | 1.01e-01 | 1.00e+00 | 3.242 | 1 | 10 | 115 |
GO:0072562 | blood microparticle | 1.02e-01 | 1.00e+00 | 3.230 | 1 | 4 | 116 |
GO:0006325 | chromatin organization | 1.07e-01 | 1.00e+00 | 3.145 | 1 | 4 | 123 |
GO:0007219 | Notch signaling pathway | 1.09e-01 | 1.00e+00 | 3.122 | 1 | 4 | 125 |
GO:0006260 | DNA replication | 1.09e-01 | 1.00e+00 | 3.122 | 1 | 12 | 125 |
GO:0007050 | cell cycle arrest | 1.10e-01 | 1.00e+00 | 3.110 | 1 | 7 | 126 |
GO:0000790 | nuclear chromatin | 1.16e-01 | 1.00e+00 | 3.032 | 1 | 7 | 133 |
GO:0000086 | G2/M transition of mitotic cell cycle | 1.19e-01 | 1.00e+00 | 2.990 | 1 | 7 | 137 |
GO:0003735 | structural constituent of ribosome | 1.22e-01 | 1.00e+00 | 2.948 | 1 | 8 | 141 |
GO:0005524 | ATP binding | 1.23e-01 | 1.00e+00 | 1.270 | 3 | 46 | 1354 |
GO:0061024 | membrane organization | 1.26e-01 | 1.00e+00 | 2.898 | 1 | 5 | 146 |
GO:0006457 | protein folding | 1.29e-01 | 1.00e+00 | 2.868 | 1 | 8 | 149 |
GO:0005737 | cytoplasm | 1.35e-01 | 1.00e+00 | 0.715 | 6 | 98 | 3976 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.44e-01 | 1.00e+00 | 2.695 | 1 | 5 | 168 |
GO:0030424 | axon | 1.47e-01 | 1.00e+00 | 2.661 | 1 | 3 | 172 |
GO:0003924 | GTPase activity | 1.71e-01 | 1.00e+00 | 2.422 | 1 | 9 | 203 |
GO:0001701 | in utero embryonic development | 1.77e-01 | 1.00e+00 | 2.373 | 1 | 6 | 210 |
GO:0006184 | GTP catabolic process | 1.84e-01 | 1.00e+00 | 2.306 | 1 | 9 | 220 |
GO:0006412 | translation | 1.96e-01 | 1.00e+00 | 2.211 | 1 | 15 | 235 |
GO:0008134 | transcription factor binding | 2.04e-01 | 1.00e+00 | 2.145 | 1 | 8 | 246 |
GO:0004842 | ubiquitin-protein transferase activity | 2.11e-01 | 1.00e+00 | 2.088 | 1 | 4 | 256 |
GO:0019899 | enzyme binding | 2.34e-01 | 1.00e+00 | 1.918 | 1 | 11 | 288 |
GO:0043234 | protein complex | 2.43e-01 | 1.00e+00 | 1.859 | 1 | 17 | 300 |
GO:0006200 | ATP catabolic process | 2.45e-01 | 1.00e+00 | 1.844 | 1 | 14 | 303 |
GO:0005856 | cytoskeleton | 2.51e-01 | 1.00e+00 | 1.807 | 1 | 8 | 311 |
GO:0019901 | protein kinase binding | 2.57e-01 | 1.00e+00 | 1.766 | 1 | 21 | 320 |
GO:0044822 | poly(A) RNA binding | 2.61e-01 | 1.00e+00 | 1.013 | 2 | 50 | 1078 |
GO:0007411 | axon guidance | 2.62e-01 | 1.00e+00 | 1.734 | 1 | 9 | 327 |
GO:0005525 | GTP binding | 2.63e-01 | 1.00e+00 | 1.730 | 1 | 11 | 328 |
GO:0003723 | RNA binding | 2.81e-01 | 1.00e+00 | 1.616 | 1 | 19 | 355 |
GO:0008285 | negative regulation of cell proliferation | 2.89e-01 | 1.00e+00 | 1.568 | 1 | 11 | 367 |
GO:0005925 | focal adhesion | 2.91e-01 | 1.00e+00 | 1.556 | 1 | 18 | 370 |
GO:0007155 | cell adhesion | 3.00e-01 | 1.00e+00 | 1.503 | 1 | 8 | 384 |
GO:0007596 | blood coagulation | 3.51e-01 | 1.00e+00 | 1.230 | 1 | 14 | 464 |
GO:0005783 | endoplasmic reticulum | 4.35e-01 | 1.00e+00 | 0.835 | 1 | 9 | 610 |
GO:0045087 | innate immune response | 4.39e-01 | 1.00e+00 | 0.821 | 1 | 20 | 616 |
GO:0005615 | extracellular space | 6.17e-01 | 1.00e+00 | 0.107 | 1 | 17 | 1010 |
GO:0005739 | mitochondrion | 6.30e-01 | 1.00e+00 | 0.057 | 1 | 24 | 1046 |
GO:0008270 | zinc ion binding | 6.37e-01 | 1.00e+00 | 0.028 | 1 | 12 | 1067 |
GO:0006351 | transcription, DNA-templated | 7.84e-01 | 1.00e+00 | -0.543 | 1 | 25 | 1585 |
GO:0005886 | plasma membrane | 9.43e-01 | 1.00e+00 | -1.381 | 1 | 38 | 2834 |