meta-int-snw-6598

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
reg-snw-5925	wolf-screen-ratio-mammosphere-adherent	0.802	2.42e-06	4.82e-03	8.69e-03	8	5
int-snw-6598	wolf-screen-ratio-mammosphere-adherent	0.956	2.37e-16	1.54e-03	2.84e-02	12	11

wolf-screen-ratio-mammosphere-adherent-meta-int-snw-6598 subnetwork

Genes (17)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PPCS	79717	31	-0.569	0.802	2	-	Yes
PPIE	10450	31	0.567	0.802	41	-	-
RPL6	6128	37	0.844	1.113	164	Yes	-
OGDH	4967	72	0.847	0.802	126	Yes	-
TFRC	7037	31	0.730	0.802	17	-	-
RPSA	3921	120	1.327	1.151	152	Yes	-
RPS3A	6189	40	0.835	1.069	166	Yes	-
PGD	5226	89	1.201	1.106	152	Yes	-
SMARCB1	6598	2	0.433	0.956	117	-	-
RPA2	6118	96	1.250	1.151	76	Yes	-
RB1	5925	31	-0.102	0.802	351	-	-
RPS11	6205	62	0.993	1.113	175	Yes	-
RPL14	9045	49	1.250	1.113	166	Yes	-
ACTB	60	134	1.153	1.151	610	Yes	-
RAN	5901	89	0.632	0.899	258	Yes	-
SAP18	10284	20	1.115	1.069	57	Yes	-
PSMD6	9861	79	0.848	0.878	143	Yes	-

Interactions (32)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
RB1	5925	PPCS	79717	pd	>	reg.pazar.txt: no annot
RB1	5925	RPA2	6118	pd	>	reg.pazar.txt: no annot
PGD	5226	RAN	5901	pp	--	int.I2D: YeastLow
RPL6	6128	RPS3A	6189	pp	--	int.I2D: BioGrid_Yeast
PGD	5226	RB1	5925	pd	<	reg.pazar.txt: no annot
RPL6	6128	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
RPS3A	6189	PSMD6	9861	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
RAN	5901	SMARCB1	6598	pp	--	int.I2D: BioGrid
RAN	5901	RPS11	6205	pp	--	int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, MINT_Worm, NON_CORE
RPSA	3921	RAN	5901	pp	--	int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
RPS3A	6189	SMARCB1	6598	pp	--	int.I2D: IntAct_Fly, BioGrid_Fly, BIND_Fly, FlyEmbryo, FlyLow, MINT_Fly
OGDH	4967	PSMD6	9861	pp	--	int.I2D: YeastLow
OGDH	4967	RB1	5925	pd	<	reg.ITFP.txt: no annot
RPS3A	6189	SAP18	10284	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, BioGrid, HPRD, MINT; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
RPS3A	6189	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
OGDH	4967	PGD	5226	pp	--	int.I2D: YeastLow
ACTB	60	RB1	5925	pd	<	reg.ITFP.txt: no annot
RPS3A	6189	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RPL6	6128	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RAN	5901	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, NON_CORE
ACTB	60	PSMD6	9861	pp	--	int.I2D: BioGrid_Yeast
RPS11	6205	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
RB1	5925	SMARCB1	6598	pp	--	int.I2D: BCI, HPRD; int.Ravasi: -; int.HPRD: in vitro
ACTB	60	RPA2	6118	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
ACTB	60	RPS3A	6189	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
RB1	5925	TFRC	7037	pd	>	reg.ITFP.txt: no annot
OGDH	4967	RPL6	6128	pp	--	int.I2D: IntAct_Yeast
OGDH	4967	RAN	5901	pp	--	int.I2D: YeastLow
RB1	5925	PPIE	10450	pd	>	reg.pazar.txt: no annot
RPSA	3921	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
RPL6	6128	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast

Related GO terms (296)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0016032	viral process	8.54e-10	1.39e-05	4.000	9	55	540
GO:0019058	viral life cycle	1.25e-09	2.03e-05	5.646	6	10	115
GO:0019083	viral transcription	1.57e-08	2.56e-04	5.889	5	8	81
GO:0006415	translational termination	2.25e-08	3.68e-04	5.786	5	8	87
GO:0006414	translational elongation	3.16e-08	5.16e-04	5.690	5	11	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	5.55e-08	9.06e-04	5.528	5	8	104
GO:0016071	mRNA metabolic process	6.64e-08	1.08e-03	4.691	6	34	223
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	8.81e-08	1.44e-03	5.396	5	10	114
GO:0016070	RNA metabolic process	1.22e-07	1.99e-03	4.544	6	34	247
GO:0006413	translational initiation	1.77e-07	2.88e-03	5.195	5	12	131
GO:0003735	structural constituent of ribosome	2.55e-07	4.16e-03	5.089	5	8	141
GO:0044822	poly(A) RNA binding	3.47e-07	5.66e-03	3.003	9	50	1078
GO:0010467	gene expression	2.56e-06	4.17e-02	3.328	7	58	669
GO:0006412	translation	3.19e-06	5.20e-02	4.352	5	15	235
GO:0044267	cellular protein metabolic process	7.03e-06	1.15e-01	3.541	6	24	495
GO:0022627	cytosolic small ribosomal subunit	8.38e-06	1.37e-01	6.207	3	3	39
GO:0030957	Tat protein binding	1.53e-05	2.49e-01	8.322	2	4	6
GO:0070062	extracellular vesicular exosome	5.09e-05	8.30e-01	1.932	10	98	2516
GO:0005829	cytosol	5.98e-05	9.75e-01	1.906	10	125	2562
GO:0016514	SWI/SNF complex	1.06e-04	1.00e+00	7.000	2	3	15
GO:0036464	cytoplasmic ribonucleoprotein granule	2.33e-04	1.00e+00	6.448	2	4	22
GO:0043044	ATP-dependent chromatin remodeling	2.55e-04	1.00e+00	6.383	2	4	23
GO:0031492	nucleosomal DNA binding	3.80e-04	1.00e+00	6.100	2	4	28
GO:0003723	RNA binding	4.19e-04	1.00e+00	3.435	4	19	355
GO:0000082	G1/S transition of mitotic cell cycle	4.71e-04	1.00e+00	4.263	3	33	150
GO:0005925	focal adhesion	4.89e-04	1.00e+00	3.376	4	18	370
GO:0005654	nucleoplasm	5.85e-04	1.00e+00	2.395	6	83	1095
GO:0050681	androgen receptor binding	7.02e-04	1.00e+00	5.659	2	4	38
GO:0030521	androgen receptor signaling pathway	8.18e-04	1.00e+00	5.549	2	2	41
GO:0034602	oxoglutarate dehydrogenase (NAD+) activity	1.04e-03	1.00e+00	9.907	1	1	1
GO:0044772	mitotic cell cycle phase transition	1.04e-03	1.00e+00	9.907	1	1	1
GO:0090230	regulation of centromere complex assembly	1.04e-03	1.00e+00	9.907	1	1	1
GO:0004632	phosphopantothenate--cysteine ligase activity	1.04e-03	1.00e+00	9.907	1	1	1
GO:0019521	D-gluconate metabolic process	1.04e-03	1.00e+00	9.907	1	1	1
GO:0016020	membrane	1.17e-03	1.00e+00	1.944	7	80	1746
GO:0022625	cytosolic large ribosomal subunit	1.17e-03	1.00e+00	5.292	2	5	49
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	1.42e-03	1.00e+00	5.152	2	5	54
GO:0003713	transcription coactivator activity	1.81e-03	1.00e+00	3.591	3	10	239
GO:0045252	oxoglutarate dehydrogenase complex	2.08e-03	1.00e+00	8.907	1	2	2
GO:0097286	iron ion import	2.08e-03	1.00e+00	8.907	1	1	2
GO:0006407	rRNA export from nucleus	2.08e-03	1.00e+00	8.907	1	1	2
GO:0061034	olfactory bulb mitral cell layer development	2.08e-03	1.00e+00	8.907	1	1	2
GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate	2.08e-03	1.00e+00	8.907	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.08e-03	1.00e+00	8.907	1	1	2
GO:0004998	transferrin receptor activity	2.08e-03	1.00e+00	8.907	1	1	2
GO:0019322	pentose biosynthetic process	2.08e-03	1.00e+00	8.907	1	1	2
GO:0031134	sister chromatid biorientation	2.08e-03	1.00e+00	8.907	1	1	2
GO:0005055	laminin receptor activity	2.08e-03	1.00e+00	8.907	1	1	2
GO:0007070	negative regulation of transcription from RNA polymerase II promoter during mitosis	2.08e-03	1.00e+00	8.907	1	2	2
GO:0006338	chromatin remodeling	2.23e-03	1.00e+00	4.820	2	4	68
GO:0000785	chromatin	2.57e-03	1.00e+00	4.717	2	5	73
GO:0061574	ASAP complex	3.12e-03	1.00e+00	8.322	1	1	3
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	3.12e-03	1.00e+00	8.322	1	1	3
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	3.12e-03	1.00e+00	8.322	1	1	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	3.12e-03	1.00e+00	8.322	1	1	3
GO:0071459	protein localization to chromosome, centromeric region	3.12e-03	1.00e+00	8.322	1	1	3
GO:0000056	ribosomal small subunit export from nucleus	3.12e-03	1.00e+00	8.322	1	1	3
GO:0009051	pentose-phosphate shunt, oxidative branch	3.12e-03	1.00e+00	8.322	1	1	3
GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle	3.12e-03	1.00e+00	8.322	1	1	3
GO:0016605	PML body	4.05e-03	1.00e+00	4.383	2	5	92
GO:0042470	melanosome	4.05e-03	1.00e+00	4.383	2	10	92
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.16e-03	1.00e+00	7.907	1	1	4
GO:0030686	90S preribosome	4.16e-03	1.00e+00	7.907	1	1	4
GO:0071922	regulation of cohesin localization to chromatin	4.16e-03	1.00e+00	7.907	1	1	4
GO:0006104	succinyl-CoA metabolic process	4.16e-03	1.00e+00	7.907	1	1	4
GO:0001835	blastocyst hatching	4.16e-03	1.00e+00	7.907	1	2	4
GO:0043550	regulation of lipid kinase activity	4.16e-03	1.00e+00	7.907	1	1	4
GO:0000055	ribosomal large subunit export from nucleus	4.16e-03	1.00e+00	7.907	1	1	4
GO:0035189	Rb-E2F complex	4.16e-03	1.00e+00	7.907	1	1	4
GO:0034088	maintenance of mitotic sister chromatid cohesion	4.16e-03	1.00e+00	7.907	1	1	4
GO:0034349	glial cell apoptotic process	4.16e-03	1.00e+00	7.907	1	1	4
GO:2000001	regulation of DNA damage checkpoint	5.20e-03	1.00e+00	7.585	1	1	5
GO:0048667	cell morphogenesis involved in neuron differentiation	5.20e-03	1.00e+00	7.585	1	1	5
GO:0000730	DNA recombinase assembly	5.20e-03	1.00e+00	7.585	1	3	5
GO:0006734	NADH metabolic process	5.20e-03	1.00e+00	7.585	1	1	5
GO:0030976	thiamine pyrophosphate binding	5.20e-03	1.00e+00	7.585	1	1	5
GO:0005515	protein binding	5.86e-03	1.00e+00	0.911	12	172	6127
GO:0030529	ribonucleoprotein complex	6.14e-03	1.00e+00	4.074	2	8	114
GO:0043353	enucleate erythrocyte differentiation	6.23e-03	1.00e+00	7.322	1	1	6
GO:0002181	cytoplasmic translation	6.23e-03	1.00e+00	7.322	1	1	6
GO:0009108	coenzyme biosynthetic process	6.23e-03	1.00e+00	7.322	1	1	6
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	6.23e-03	1.00e+00	7.322	1	1	6
GO:0021860	pyramidal neuron development	6.23e-03	1.00e+00	7.322	1	1	6
GO:0021695	cerebellar cortex development	6.23e-03	1.00e+00	7.322	1	1	6
GO:0072562	blood microparticle	6.35e-03	1.00e+00	4.049	2	4	116
GO:0000028	ribosomal small subunit assembly	7.27e-03	1.00e+00	7.100	1	1	7
GO:0016018	cyclosporin A binding	7.27e-03	1.00e+00	7.100	1	1	7
GO:0000278	mitotic cell cycle	7.59e-03	1.00e+00	2.855	3	52	398
GO:0000790	nuclear chromatin	8.27e-03	1.00e+00	3.852	2	7	133
GO:0070688	MLL5-L complex	8.30e-03	1.00e+00	6.907	1	1	8
GO:0006554	lysine catabolic process	8.30e-03	1.00e+00	6.907	1	2	8
GO:0015074	DNA integration	8.30e-03	1.00e+00	6.907	1	1	8
GO:0044281	small molecule metabolic process	8.61e-03	1.00e+00	1.890	5	57	1295
GO:0015937	coenzyme A biosynthetic process	9.34e-03	1.00e+00	6.737	1	1	9
GO:0097284	hepatocyte apoptotic process	9.34e-03	1.00e+00	6.737	1	2	9
GO:0000075	cell cycle checkpoint	9.34e-03	1.00e+00	6.737	1	2	9
GO:0006457	protein folding	1.03e-02	1.00e+00	3.688	2	8	149
GO:0015939	pantothenate metabolic process	1.04e-02	1.00e+00	6.585	1	1	10
GO:0021756	striatum development	1.04e-02	1.00e+00	6.585	1	1	10
GO:0006098	pentose-phosphate shunt	1.14e-02	1.00e+00	6.448	1	3	11
GO:0010569	regulation of double-strand break repair via homologous recombination	1.14e-02	1.00e+00	6.448	1	1	11
GO:0031571	mitotic G1 DNA damage checkpoint	1.14e-02	1.00e+00	6.448	1	3	11
GO:0042551	neuron maturation	1.14e-02	1.00e+00	6.448	1	2	11
GO:0045651	positive regulation of macrophage differentiation	1.14e-02	1.00e+00	6.448	1	2	11
GO:0043923	positive regulation by host of viral transcription	1.14e-02	1.00e+00	6.448	1	2	11
GO:0071564	npBAF complex	1.14e-02	1.00e+00	6.448	1	2	11
GO:0005634	nucleus	1.14e-02	1.00e+00	0.992	10	131	4828
GO:0071565	nBAF complex	1.24e-02	1.00e+00	6.322	1	2	12
GO:0051146	striated muscle cell differentiation	1.24e-02	1.00e+00	6.322	1	1	12
GO:0021794	thalamus development	1.24e-02	1.00e+00	6.322	1	1	12
GO:0001741	XY body	1.24e-02	1.00e+00	6.322	1	1	12
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.29e-02	1.00e+00	3.515	2	5	168
GO:0042273	ribosomal large subunit biogenesis	1.35e-02	1.00e+00	6.207	1	4	13
GO:0005662	DNA replication factor A complex	1.35e-02	1.00e+00	6.207	1	3	13
GO:0045780	positive regulation of bone resorption	1.35e-02	1.00e+00	6.207	1	1	13
GO:0034641	cellular nitrogen compound metabolic process	1.43e-02	1.00e+00	3.439	2	25	177
GO:0035267	NuA4 histone acetyltransferase complex	1.45e-02	1.00e+00	6.100	1	4	14
GO:0031625	ubiquitin protein ligase binding	1.48e-02	1.00e+00	3.415	2	13	180
GO:0045445	myoblast differentiation	1.55e-02	1.00e+00	6.000	1	2	15
GO:0048025	negative regulation of mRNA splicing, via spliceosome	1.55e-02	1.00e+00	6.000	1	1	15
GO:0050998	nitric-oxide synthase binding	1.65e-02	1.00e+00	5.907	1	1	16
GO:0006103	2-oxoglutarate metabolic process	1.65e-02	1.00e+00	5.907	1	1	16
GO:0006337	nucleosome disassembly	1.76e-02	1.00e+00	5.820	1	4	17
GO:0045070	positive regulation of viral genome replication	1.76e-02	1.00e+00	5.820	1	1	17
GO:0075733	intracellular transport of virus	1.76e-02	1.00e+00	5.820	1	2	17
GO:0022624	proteasome accessory complex	1.76e-02	1.00e+00	5.820	1	9	17
GO:0035861	site of double-strand break	1.86e-02	1.00e+00	5.737	1	1	18
GO:0035145	exon-exon junction complex	1.96e-02	1.00e+00	5.659	1	2	19
GO:0006259	DNA metabolic process	1.96e-02	1.00e+00	5.659	1	3	19
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	2.06e-02	1.00e+00	5.585	1	2	20
GO:0006298	mismatch repair	2.06e-02	1.00e+00	5.585	1	6	20
GO:0000718	nucleotide-excision repair, DNA damage removal	2.17e-02	1.00e+00	5.515	1	5	21
GO:0030316	osteoclast differentiation	2.27e-02	1.00e+00	5.448	1	2	22
GO:0006297	nucleotide-excision repair, DNA gap filling	2.27e-02	1.00e+00	5.448	1	5	22
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	2.27e-02	1.00e+00	5.448	1	3	22
GO:0032201	telomere maintenance via semi-conservative replication	2.27e-02	1.00e+00	5.448	1	7	22
GO:0030863	cortical cytoskeleton	2.27e-02	1.00e+00	5.448	1	1	22
GO:0007052	mitotic spindle organization	2.27e-02	1.00e+00	5.448	1	2	22
GO:0043236	laminin binding	2.37e-02	1.00e+00	5.383	1	1	23
GO:0045879	negative regulation of smoothened signaling pathway	2.37e-02	1.00e+00	5.383	1	1	23
GO:0006611	protein export from nucleus	2.57e-02	1.00e+00	5.263	1	4	25
GO:0000722	telomere maintenance via recombination	2.68e-02	1.00e+00	5.207	1	7	26
GO:0019843	rRNA binding	2.78e-02	1.00e+00	5.152	1	3	27
GO:0048565	digestive tract development	2.78e-02	1.00e+00	5.152	1	1	27
GO:0043022	ribosome binding	2.88e-02	1.00e+00	5.100	1	3	28
GO:0000118	histone deacetylase complex	2.88e-02	1.00e+00	5.100	1	1	28
GO:0019894	kinesin binding	2.88e-02	1.00e+00	5.100	1	1	28
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	2.98e-02	1.00e+00	5.049	1	2	29
GO:0006099	tricarboxylic acid cycle	2.98e-02	1.00e+00	5.049	1	3	29
GO:0006281	DNA repair	3.02e-02	1.00e+00	2.863	2	22	264
GO:0007346	regulation of mitotic cell cycle	3.08e-02	1.00e+00	5.000	1	3	30
GO:0006271	DNA strand elongation involved in DNA replication	3.18e-02	1.00e+00	4.953	1	9	31
GO:0007093	mitotic cell cycle checkpoint	3.18e-02	1.00e+00	4.953	1	2	31
GO:0006357	regulation of transcription from RNA polymerase II promoter	3.26e-02	1.00e+00	2.804	2	6	275
GO:0050661	NADP binding	3.28e-02	1.00e+00	4.907	1	1	32
GO:0051219	phosphoprotein binding	3.28e-02	1.00e+00	4.907	1	3	32
GO:0033572	transferrin transport	3.28e-02	1.00e+00	4.907	1	6	32
GO:1903507	negative regulation of nucleic acid-templated transcription	3.28e-02	1.00e+00	4.907	1	2	32
GO:0031072	heat shock protein binding	3.38e-02	1.00e+00	4.863	1	2	33
GO:0000413	protein peptidyl-prolyl isomerization	3.48e-02	1.00e+00	4.820	1	1	34
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	3.48e-02	1.00e+00	4.820	1	1	34
GO:0034332	adherens junction organization	3.69e-02	1.00e+00	4.737	1	1	36
GO:0051402	neuron apoptotic process	3.69e-02	1.00e+00	4.737	1	2	36
GO:0001895	retina homeostasis	3.69e-02	1.00e+00	4.737	1	1	36
GO:0001102	RNA polymerase II activating transcription factor binding	3.79e-02	1.00e+00	4.698	1	4	37
GO:0051084	'de novo' posttranslational protein folding	3.79e-02	1.00e+00	4.698	1	4	37
GO:0043234	protein complex	3.82e-02	1.00e+00	2.678	2	17	300
GO:0070527	platelet aggregation	3.89e-02	1.00e+00	4.659	1	2	38
GO:0021766	hippocampus development	3.99e-02	1.00e+00	4.622	1	4	39
GO:0006284	base-excision repair	3.99e-02	1.00e+00	4.622	1	7	39
GO:0006096	glycolytic process	3.99e-02	1.00e+00	4.622	1	4	39
GO:0032092	positive regulation of protein binding	3.99e-02	1.00e+00	4.622	1	3	39
GO:0000781	chromosome, telomeric region	4.09e-02	1.00e+00	4.585	1	2	40
GO:0035914	skeletal muscle cell differentiation	4.29e-02	1.00e+00	4.515	1	1	42
GO:0030154	cell differentiation	4.42e-02	1.00e+00	2.563	2	5	325
GO:0007286	spermatid development	4.49e-02	1.00e+00	4.448	1	1	44
GO:0021762	substantia nigra development	4.69e-02	1.00e+00	4.383	1	1	46
GO:0001047	core promoter binding	4.69e-02	1.00e+00	4.383	1	2	46
GO:0006283	transcription-coupled nucleotide-excision repair	4.69e-02	1.00e+00	4.383	1	8	46
GO:0019003	GDP binding	4.89e-02	1.00e+00	4.322	1	2	48
GO:0006521	regulation of cellular amino acid metabolic process	5.08e-02	1.00e+00	4.263	1	21	50
GO:0006091	generation of precursor metabolites and energy	5.18e-02	1.00e+00	4.235	1	3	51
GO:0005905	coated pit	5.18e-02	1.00e+00	4.235	1	2	51
GO:0003684	damaged DNA binding	5.18e-02	1.00e+00	4.235	1	11	51
GO:0003725	double-stranded RNA binding	5.48e-02	1.00e+00	4.152	1	6	54
GO:0019900	kinase binding	5.48e-02	1.00e+00	4.152	1	1	54
GO:0050680	negative regulation of epithelial cell proliferation	5.48e-02	1.00e+00	4.152	1	1	54
GO:0002039	p53 binding	5.58e-02	1.00e+00	4.126	1	7	55
GO:0006879	cellular iron ion homeostasis	5.78e-02	1.00e+00	4.074	1	5	57
GO:0000724	double-strand break repair via homologous recombination	5.78e-02	1.00e+00	4.074	1	6	57
GO:0000502	proteasome complex	5.88e-02	1.00e+00	4.049	1	22	58
GO:0005840	ribosome	5.97e-02	1.00e+00	4.024	1	2	59
GO:0051087	chaperone binding	5.97e-02	1.00e+00	4.024	1	6	59
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	5.97e-02	1.00e+00	4.024	1	4	59
GO:0045216	cell-cell junction organization	5.97e-02	1.00e+00	4.024	1	2	59
GO:0000723	telomere maintenance	5.97e-02	1.00e+00	4.024	1	8	59
GO:0005643	nuclear pore	5.97e-02	1.00e+00	4.024	1	4	59
GO:0031966	mitochondrial membrane	5.97e-02	1.00e+00	4.024	1	1	59
GO:0006302	double-strand break repair	6.27e-02	1.00e+00	3.953	1	8	62
GO:0019903	protein phosphatase binding	6.37e-02	1.00e+00	3.930	1	4	63
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.56e-02	1.00e+00	3.885	1	24	65
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	6.56e-02	1.00e+00	3.885	1	22	65
GO:0006469	negative regulation of protein kinase activity	6.56e-02	1.00e+00	3.885	1	2	65
GO:0001558	regulation of cell growth	6.66e-02	1.00e+00	3.863	1	4	66
GO:0006289	nucleotide-excision repair	6.95e-02	1.00e+00	3.798	1	12	69
GO:0003697	single-stranded DNA binding	6.95e-02	1.00e+00	3.798	1	9	69
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	7.05e-02	1.00e+00	3.778	1	24	70
GO:0034329	cell junction assembly	7.15e-02	1.00e+00	3.757	1	1	71
GO:0055037	recycling endosome	7.34e-02	1.00e+00	3.717	1	2	73
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	7.34e-02	1.00e+00	3.717	1	23	73
GO:0043066	negative regulation of apoptotic process	7.35e-02	1.00e+00	2.149	2	30	433
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	7.44e-02	1.00e+00	3.698	1	24	74
GO:0006767	water-soluble vitamin metabolic process	7.53e-02	1.00e+00	3.678	1	3	75
GO:0007265	Ras protein signal transduction	7.53e-02	1.00e+00	3.678	1	3	75
GO:0031175	neuron projection development	7.53e-02	1.00e+00	3.678	1	1	75
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	7.73e-02	1.00e+00	3.640	1	5	77
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	7.73e-02	1.00e+00	3.640	1	23	77
GO:0006766	vitamin metabolic process	7.82e-02	1.00e+00	3.622	1	3	78
GO:0071013	catalytic step 2 spliceosome	7.92e-02	1.00e+00	3.603	1	7	79
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	7.92e-02	1.00e+00	3.603	1	25	79
GO:0047485	protein N-terminus binding	8.59e-02	1.00e+00	3.481	1	4	86
GO:0006898	receptor-mediated endocytosis	8.59e-02	1.00e+00	3.481	1	2	86
GO:0045893	positive regulation of transcription, DNA-templated	9.00e-02	1.00e+00	1.979	2	17	487
GO:0005730	nucleolus	9.04e-02	1.00e+00	1.189	4	70	1684
GO:0042802	identical protein binding	9.13e-02	1.00e+00	1.967	2	18	491
GO:0006928	cellular component movement	9.17e-02	1.00e+00	3.383	1	7	92
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	9.26e-02	1.00e+00	3.368	1	5	93
GO:0005200	structural constituent of cytoskeleton	9.26e-02	1.00e+00	3.368	1	7	93
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	9.36e-02	1.00e+00	3.352	1	23	94
GO:0001649	osteoblast differentiation	9.45e-02	1.00e+00	3.337	1	6	95
GO:0006364	rRNA processing	9.55e-02	1.00e+00	3.322	1	5	96
GO:0014069	postsynaptic density	1.05e-01	1.00e+00	3.179	1	1	106
GO:0016023	cytoplasmic membrane-bounded vesicle	1.06e-01	1.00e+00	3.166	1	3	107
GO:0042127	regulation of cell proliferation	1.10e-01	1.00e+00	3.113	1	4	111
GO:0005819	spindle	1.12e-01	1.00e+00	3.074	1	7	114
GO:0000209	protein polyubiquitination	1.14e-01	1.00e+00	3.049	1	21	116
GO:0044237	cellular metabolic process	1.16e-01	1.00e+00	3.024	1	3	118
GO:0006325	chromatin organization	1.21e-01	1.00e+00	2.964	1	4	123
GO:0007050	cell cycle arrest	1.23e-01	1.00e+00	2.930	1	7	126
GO:0006260	DNA replication	1.23e-01	1.00e+00	2.941	1	12	125
GO:0031982	vesicle	1.31e-01	1.00e+00	2.841	1	10	134
GO:0016887	ATPase activity	1.40e-01	1.00e+00	2.737	1	7	144
GO:0061024	membrane organization	1.42e-01	1.00e+00	2.717	1	5	146
GO:0042981	regulation of apoptotic process	1.46e-01	1.00e+00	2.669	1	26	151
GO:0000398	mRNA splicing, via spliceosome	1.59e-01	1.00e+00	2.541	1	12	165
GO:0006397	mRNA processing	1.62e-01	1.00e+00	2.506	1	3	169
GO:0030424	axon	1.65e-01	1.00e+00	2.481	1	3	172
GO:0005768	endosome	1.67e-01	1.00e+00	2.464	1	5	174
GO:0016607	nuclear speck	1.68e-01	1.00e+00	2.456	1	4	175
GO:0003714	transcription corepressor activity	1.71e-01	1.00e+00	2.423	1	7	179
GO:0019904	protein domain specific binding	1.73e-01	1.00e+00	2.407	1	6	181
GO:0009897	external side of plasma membrane	1.75e-01	1.00e+00	2.391	1	4	183
GO:0003924	GTPase activity	1.92e-01	1.00e+00	2.242	1	9	203
GO:0006184	GTP catabolic process	2.06e-01	1.00e+00	2.126	1	9	220
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	2.06e-01	1.00e+00	1.243	2	19	811
GO:0005737	cytoplasm	2.15e-01	1.00e+00	0.535	6	98	3976
GO:0007067	mitotic nuclear division	2.15e-01	1.00e+00	2.055	1	13	231
GO:0008380	RNA splicing	2.16e-01	1.00e+00	2.049	1	13	232
GO:0005759	mitochondrial matrix	2.17e-01	1.00e+00	2.043	1	12	233
GO:0006351	transcription, DNA-templated	2.25e-01	1.00e+00	0.862	3	25	1585
GO:0007399	nervous system development	2.27e-01	1.00e+00	1.970	1	2	245
GO:0008134	transcription factor binding	2.28e-01	1.00e+00	1.964	1	8	246
GO:0000166	nucleotide binding	2.49e-01	1.00e+00	1.820	1	6	272
GO:0005975	carbohydrate metabolic process	2.50e-01	1.00e+00	1.809	1	5	274
GO:0043065	positive regulation of apoptotic process	2.50e-01	1.00e+00	1.809	1	8	274
GO:0019899	enzyme binding	2.61e-01	1.00e+00	1.737	1	11	288
GO:0007264	small GTPase mediated signal transduction	2.63e-01	1.00e+00	1.727	1	3	290
GO:0006200	ATP catabolic process	2.73e-01	1.00e+00	1.664	1	14	303
GO:0005856	cytoskeleton	2.79e-01	1.00e+00	1.626	1	8	311
GO:0005615	extracellular space	2.84e-01	1.00e+00	0.927	2	17	1010
GO:0019901	protein kinase binding	2.86e-01	1.00e+00	1.585	1	21	320
GO:0007411	axon guidance	2.91e-01	1.00e+00	1.554	1	9	327
GO:0005525	GTP binding	2.92e-01	1.00e+00	1.549	1	11	328
GO:0043231	intracellular membrane-bounded organelle	2.95e-01	1.00e+00	1.532	1	8	332
GO:0003682	chromatin binding	2.96e-01	1.00e+00	1.523	1	12	334
GO:0006355	regulation of transcription, DNA-templated	3.21e-01	1.00e+00	0.798	2	17	1104
GO:0008285	negative regulation of cell proliferation	3.21e-01	1.00e+00	1.387	1	11	367
GO:0007155	cell adhesion	3.33e-01	1.00e+00	1.322	1	8	384
GO:0006508	proteolysis	3.51e-01	1.00e+00	1.227	1	9	410
GO:0009986	cell surface	3.60e-01	1.00e+00	1.186	1	9	422
GO:0045892	negative regulation of transcription, DNA-templated	3.61e-01	1.00e+00	1.179	1	14	424
GO:0007596	blood coagulation	3.88e-01	1.00e+00	1.049	1	14	464
GO:0055114	oxidation-reduction process	3.99e-01	1.00e+00	0.997	1	11	481
GO:0003677	DNA binding	4.17e-01	1.00e+00	0.507	2	26	1351
GO:0055085	transmembrane transport	4.20e-01	1.00e+00	0.901	1	8	514
GO:0048471	perinuclear region of cytoplasm	4.25e-01	1.00e+00	0.876	1	12	523
GO:0006915	apoptotic process	4.54e-01	1.00e+00	0.750	1	34	571
GO:0045087	innate immune response	4.80e-01	1.00e+00	0.640	1	20	616
GO:0003700	sequence-specific DNA binding transcription factor activity	5.50e-01	1.00e+00	0.360	1	11	748
GO:0007165	signal transduction	6.39e-01	1.00e+00	0.015	1	17	950
GO:0005887	integral component of plasma membrane	6.44e-01	1.00e+00	-0.001	1	7	961
GO:0005739	mitochondrion	6.76e-01	1.00e+00	-0.124	1	24	1046
GO:0005576	extracellular region	6.77e-01	1.00e+00	-0.128	1	9	1049
GO:0005524	ATP binding	7.71e-01	1.00e+00	-0.496	1	46	1354
GO:0046872	metal ion binding	7.98e-01	1.00e+00	-0.610	1	24	1465
GO:0005886	plasma membrane	8.22e-01	1.00e+00	-0.562	2	38	2834

Wolf-ratios-Mammosphere-Adherent

meta-int-snw-6598

Interacting subnets

Genes (17)

Interactions (32)

Related GO terms (296)