meta-int-snw-6120

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
reg-snw-11277	wolf-screen-ratio-mammosphere-adherent	0.882	1.09e-07	9.11e-04	1.96e-03	10	9
int-snw-6120	wolf-screen-ratio-mammosphere-adherent	0.948	4.91e-16	1.84e-03	3.24e-02	9	8
reg-snw-5925	wolf-screen-ratio-mammosphere-adherent	0.802	2.42e-06	4.82e-03	8.69e-03	8	5

wolf-screen-ratio-mammosphere-adherent-meta-int-snw-6120 subnetwork

Genes (21)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PSMB1	5689	61	0.688	0.901	113	Yes	-
PPCS	79717	31	-0.569	0.802	2	-	Yes
RBX1	9978	115	1.185	0.934	148	Yes	-
PPIE	10450	31	0.567	0.802	41	-	-
PSMB7	5695	118	0.982	0.934	90	Yes	-
HNRNPC	3183	108	1.812	0.973	181	Yes	-
TREX1	11277	51	-0.051	0.882	91	Yes	-
OGDH	4967	72	0.847	0.802	126	Yes	-
RPE	6120	3	0.024	0.948	34	-	-
TFRC	7037	31	0.730	0.802	17	-	-
RPSA	3921	120	1.327	1.151	152	Yes	-
PGD	5226	89	1.201	1.106	152	Yes	-
RPA2	6118	96	1.250	1.151	76	Yes	-
CAD	790	91	0.807	0.973	400	-	-
RB1	5925	31	-0.102	0.802	351	-	-
PSMB2	5690	116	0.877	0.956	169	Yes	-
NAA10	8260	5	0.668	0.983	136	Yes	-
PSMD11	5717	124	1.095	1.106	218	Yes	-
ACTB	60	134	1.153	1.151	610	Yes	-
RUVBL2	10856	95	0.693	0.956	532	Yes	-
RAN	5901	89	0.632	0.899	258	Yes	-

Interactions (54)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
RB1	5925	PPCS	79717	pd	>	reg.pazar.txt: no annot
PSMB2	5690	TREX1	11277	pd	<	reg.ITFP.txt: no annot
RB1	5925	RPA2	6118	pd	>	reg.pazar.txt: no annot
PGD	5226	RAN	5901	pp	--	int.I2D: YeastLow
CAD	790	TREX1	11277	pd	<	reg.ITFP.txt: no annot
PSMB1	5689	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
PGD	5226	RB1	5925	pd	<	reg.pazar.txt: no annot
ACTB	60	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast
PSMB1	5689	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast, MINT, YeastHigh, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast; int.Mint: MI:0915(physical association)
RBX1	9978	PPIE	10450	pd	<>	reg.ITFP.txt: no annot
ACTB	60	RBX1	9978	pp	--	int.I2D: BioGrid_Yeast
RPSA	3921	RAN	5901	pp	--	int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
RPSA	3921	NAA10	8260	pp	--	int.I2D: IntAct_Yeast
ACTB	60	RPE	6120	pp	--	int.I2D: BioGrid_Yeast
OGDH	4967	RB1	5925	pd	<	reg.ITFP.txt: no annot
ACTB	60	CAD	790	pp	--	int.I2D: IntAct_Yeast
OGDH	4967	PGD	5226	pp	--	int.I2D: YeastLow
PSMB7	5695	RBX1	9978	pd	<	reg.ITFP.txt: no annot
CAD	790	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
CAD	790	RUVBL2	10856	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
PSMB7	5695	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	NAA10	8260	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RB1	5925	pd	<	reg.ITFP.txt: no annot
RAN	5901	RPE	6120	pp	--	int.I2D: YeastLow
HNRNPC	3183	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
PSMB1	5689	PSMB7	5695	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastLow, IntAct, Krogan_Core, MINT_Yeast, Yu_GoldStd; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PSMB2	5690	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
CAD	790	NAA10	8260	pp	--	int.I2D: IntAct_Yeast
ACTB	60	RAN	5901	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, NON_CORE
CAD	790	RAN	5901	pp	--	int.I2D: IntAct_Yeast
PSMB7	5695	TREX1	11277	pd	<	reg.ITFP.txt: no annot
RPSA	3921	RUVBL2	10856	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB	60	PSMB7	5695	pp	--	int.I2D: BioGrid_Yeast
RPE	6120	NAA10	8260	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RPA2	6118	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
CAD	790	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast
PSMD11	5717	RUVBL2	10856	pp	--	int.I2D: YeastLow
OGDH	4967	PSMD11	5717	pp	--	int.I2D: YeastLow
PGD	5226	RPE	6120	pp	--	int.I2D: BioGrid_Yeast
PSMB7	5695	PPIE	10450	pd	<	reg.ITFP.txt: no annot
PSMB1	5689	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
PSMB1	5689	TREX1	11277	pd	<	reg.ITFP.txt: no annot
RB1	5925	TFRC	7037	pd	>	reg.ITFP.txt: no annot
OGDH	4967	RAN	5901	pp	--	int.I2D: YeastLow
PSMB2	5690	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
RB1	5925	PPIE	10450	pd	>	reg.pazar.txt: no annot
RAN	5901	TREX1	11277	pd	<	reg.ITFP.txt: no annot
RUVBL2	10856	TREX1	11277	pd	<>	reg.ITFP.txt: no annot
ACTB	60	RUVBL2	10856	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
CAD	790	RPSA	3921	pp	--	int.I2D: IntAct_Yeast

Related GO terms (376)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0016032	viral process	9.17e-09	1.50e-04	3.695	9	55	540
GO:0005654	nucleoplasm	2.23e-08	3.64e-04	2.965	11	83	1095
GO:0000082	G1/S transition of mitotic cell cycle	2.64e-08	4.31e-04	4.958	6	33	150
GO:0070062	extracellular vesicular exosome	1.64e-07	2.68e-03	2.113	14	98	2516
GO:0005829	cytosol	2.07e-07	3.38e-03	2.086	14	125	2562
GO:0006521	regulation of cellular amino acid metabolic process	4.49e-07	7.33e-03	5.958	4	21	50
GO:0000502	proteasome complex	8.21e-07	1.34e-02	5.744	4	22	58
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.30e-06	2.13e-02	5.580	4	24	65
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.30e-06	2.13e-02	5.580	4	22	65
GO:0005839	proteasome core complex	1.48e-06	2.41e-02	7.017	3	11	18
GO:0044281	small molecule metabolic process	1.50e-06	2.44e-02	2.585	10	57	1295
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.76e-06	2.87e-02	5.473	4	24	70
GO:0004298	threonine-type endopeptidase activity	2.06e-06	3.37e-02	6.865	3	11	20
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	2.08e-06	3.40e-02	5.412	4	23	73
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.20e-06	3.59e-02	5.393	4	24	74
GO:0034641	cellular nitrogen compound metabolic process	2.51e-06	4.09e-02	4.456	5	25	177
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	2.58e-06	4.21e-02	5.335	4	23	77
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	2.86e-06	4.66e-02	5.298	4	25	79
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	5.73e-06	9.35e-02	5.048	4	23	94
GO:0016071	mRNA metabolic process	7.75e-06	1.27e-01	4.123	5	34	223
GO:0000278	mitotic cell cycle	8.06e-06	1.31e-01	3.550	6	52	398
GO:0016070	RNA metabolic process	1.27e-05	2.08e-01	3.976	5	34	247
GO:0000209	protein polyubiquitination	1.32e-05	2.16e-01	4.744	4	21	116
GO:0010467	gene expression	1.32e-05	2.16e-01	3.024	7	58	669
GO:0016020	membrane	2.22e-05	3.62e-01	2.154	10	80	1746
GO:0042802	identical protein binding	2.65e-05	4.33e-01	3.248	6	18	491
GO:0042981	regulation of apoptotic process	3.73e-05	6.08e-01	4.364	4	26	151
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	4.37e-05	7.12e-01	5.432	3	5	54
GO:0006098	pentose-phosphate shunt	8.61e-05	1.00e+00	7.143	2	3	11
GO:0005634	nucleus	8.97e-05	1.00e+00	1.272	15	131	4828
GO:0035267	NuA4 histone acetyltransferase complex	1.42e-04	1.00e+00	6.795	2	4	14
GO:0006259	DNA metabolic process	2.66e-04	1.00e+00	6.354	2	3	19
GO:0006298	mismatch repair	2.95e-04	1.00e+00	6.280	2	6	20
GO:0006281	DNA repair	3.22e-04	1.00e+00	3.558	4	22	264
GO:0043044	ATP-dependent chromatin remodeling	3.92e-04	1.00e+00	6.079	2	4	23
GO:0043022	ribosome binding	5.84e-04	1.00e+00	5.795	2	3	28
GO:0031492	nucleosomal DNA binding	5.84e-04	1.00e+00	5.795	2	4	28
GO:0006457	protein folding	8.79e-04	1.00e+00	3.968	3	8	149
GO:0050681	androgen receptor binding	1.08e-03	1.00e+00	5.354	2	4	38
GO:0030521	androgen receptor signaling pathway	1.25e-03	1.00e+00	5.245	2	2	41
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	1.29e-03	1.00e+00	9.602	1	1	1
GO:0034602	oxoglutarate dehydrogenase (NAD+) activity	1.29e-03	1.00e+00	9.602	1	1	1
GO:0070335	aspartate binding	1.29e-03	1.00e+00	9.602	1	1	1
GO:0032558	adenyl deoxyribonucleotide binding	1.29e-03	1.00e+00	9.602	1	1	1
GO:0004750	ribulose-phosphate 3-epimerase activity	1.29e-03	1.00e+00	9.602	1	1	1
GO:0090230	regulation of centromere complex assembly	1.29e-03	1.00e+00	9.602	1	1	1
GO:0004151	dihydroorotase activity	1.29e-03	1.00e+00	9.602	1	1	1
GO:0004632	phosphopantothenate--cysteine ligase activity	1.29e-03	1.00e+00	9.602	1	1	1
GO:0019521	D-gluconate metabolic process	1.29e-03	1.00e+00	9.602	1	1	1
GO:0004070	aspartate carbamoyltransferase activity	1.29e-03	1.00e+00	9.602	1	1	1
GO:0031625	ubiquitin protein ligase binding	1.52e-03	1.00e+00	3.695	3	13	180
GO:0005515	protein binding	1.69e-03	1.00e+00	0.928	15	172	6127
GO:0003684	damaged DNA binding	1.94e-03	1.00e+00	4.930	2	11	51
GO:0043066	negative regulation of apoptotic process	2.04e-03	1.00e+00	2.844	4	30	433
GO:0045252	oxoglutarate dehydrogenase complex	2.57e-03	1.00e+00	8.602	1	2	2
GO:0097286	iron ion import	2.57e-03	1.00e+00	8.602	1	1	2
GO:0006407	rRNA export from nucleus	2.57e-03	1.00e+00	8.602	1	1	2
GO:0061034	olfactory bulb mitral cell layer development	2.57e-03	1.00e+00	8.602	1	1	2
GO:0008296	3'-5'-exodeoxyribonuclease activity	2.57e-03	1.00e+00	8.602	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.57e-03	1.00e+00	8.602	1	1	2
GO:0004998	transferrin receptor activity	2.57e-03	1.00e+00	8.602	1	1	2
GO:0019322	pentose biosynthetic process	2.57e-03	1.00e+00	8.602	1	1	2
GO:0031134	sister chromatid biorientation	2.57e-03	1.00e+00	8.602	1	1	2
GO:0005055	laminin receptor activity	2.57e-03	1.00e+00	8.602	1	1	2
GO:0007070	negative regulation of transcription from RNA polymerase II promoter during mitosis	2.57e-03	1.00e+00	8.602	1	2	2
GO:0070409	carbamoyl phosphate biosynthetic process	2.57e-03	1.00e+00	8.602	1	1	2
GO:0006310	DNA recombination	3.32e-03	1.00e+00	4.536	2	4	67
GO:0006338	chromatin remodeling	3.41e-03	1.00e+00	4.515	2	4	68
GO:0003697	single-stranded DNA binding	3.51e-03	1.00e+00	4.494	2	9	69
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	3.86e-03	1.00e+00	8.017	1	1	3
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	3.86e-03	1.00e+00	8.017	1	1	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	3.86e-03	1.00e+00	8.017	1	1	3
GO:0071459	protein localization to chromosome, centromeric region	3.86e-03	1.00e+00	8.017	1	1	3
GO:0071899	negative regulation of estrogen receptor binding	3.86e-03	1.00e+00	8.017	1	1	3
GO:0071733	transcriptional activation by promoter-enhancer looping	3.86e-03	1.00e+00	8.017	1	1	3
GO:0000056	ribosomal small subunit export from nucleus	3.86e-03	1.00e+00	8.017	1	1	3
GO:0009051	pentose-phosphate shunt, oxidative branch	3.86e-03	1.00e+00	8.017	1	1	3
GO:0044205	'de novo' UMP biosynthetic process	3.86e-03	1.00e+00	8.017	1	1	3
GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle	3.86e-03	1.00e+00	8.017	1	1	3
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	3.86e-03	1.00e+00	8.017	1	1	3
GO:0005730	nucleolus	3.88e-03	1.00e+00	1.692	7	70	1684
GO:0000785	chromatin	3.92e-03	1.00e+00	4.412	2	5	73
GO:0071013	catalytic step 2 spliceosome	4.58e-03	1.00e+00	4.298	2	7	79
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	5.14e-03	1.00e+00	7.602	1	1	4
GO:0030686	90S preribosome	5.14e-03	1.00e+00	7.602	1	1	4
GO:0071922	regulation of cohesin localization to chromatin	5.14e-03	1.00e+00	7.602	1	1	4
GO:0019788	NEDD8 ligase activity	5.14e-03	1.00e+00	7.602	1	1	4
GO:0043141	ATP-dependent 5'-3' DNA helicase activity	5.14e-03	1.00e+00	7.602	1	1	4
GO:0006104	succinyl-CoA metabolic process	5.14e-03	1.00e+00	7.602	1	1	4
GO:0006543	glutamine catabolic process	5.14e-03	1.00e+00	7.602	1	1	4
GO:0031467	Cul7-RING ubiquitin ligase complex	5.14e-03	1.00e+00	7.602	1	1	4
GO:0043550	regulation of lipid kinase activity	5.14e-03	1.00e+00	7.602	1	1	4
GO:0000055	ribosomal large subunit export from nucleus	5.14e-03	1.00e+00	7.602	1	1	4
GO:0035189	Rb-E2F complex	5.14e-03	1.00e+00	7.602	1	1	4
GO:0034349	glial cell apoptotic process	5.14e-03	1.00e+00	7.602	1	1	4
GO:0034088	maintenance of mitotic sister chromatid cohesion	5.14e-03	1.00e+00	7.602	1	1	4
GO:0008853	exodeoxyribonuclease III activity	5.14e-03	1.00e+00	7.602	1	1	4
GO:0006915	apoptotic process	5.52e-03	1.00e+00	2.445	4	34	571
GO:0016363	nuclear matrix	6.16e-03	1.00e+00	4.079	2	11	92
GO:0016605	PML body	6.16e-03	1.00e+00	4.079	2	5	92
GO:0042470	melanosome	6.16e-03	1.00e+00	4.079	2	10	92
GO:0043234	protein complex	6.40e-03	1.00e+00	2.958	3	17	300
GO:0051414	response to cortisol	6.42e-03	1.00e+00	7.280	1	1	5
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	6.42e-03	1.00e+00	7.280	1	2	5
GO:0032407	MutSalpha complex binding	6.42e-03	1.00e+00	7.280	1	1	5
GO:2000001	regulation of DNA damage checkpoint	6.42e-03	1.00e+00	7.280	1	1	5
GO:0031415	NatA complex	6.42e-03	1.00e+00	7.280	1	1	5
GO:0031461	cullin-RING ubiquitin ligase complex	6.42e-03	1.00e+00	7.280	1	1	5
GO:0071169	establishment of protein localization to chromatin	6.42e-03	1.00e+00	7.280	1	1	5
GO:0043248	proteasome assembly	6.42e-03	1.00e+00	7.280	1	1	5
GO:0006323	DNA packaging	6.42e-03	1.00e+00	7.280	1	1	5
GO:0048667	cell morphogenesis involved in neuron differentiation	6.42e-03	1.00e+00	7.280	1	1	5
GO:0030891	VCB complex	6.42e-03	1.00e+00	7.280	1	2	5
GO:0000730	DNA recombinase assembly	6.42e-03	1.00e+00	7.280	1	3	5
GO:0006734	NADH metabolic process	6.42e-03	1.00e+00	7.280	1	1	5
GO:0030976	thiamine pyrophosphate binding	6.42e-03	1.00e+00	7.280	1	1	5
GO:0043353	enucleate erythrocyte differentiation	7.70e-03	1.00e+00	7.017	1	1	6
GO:0009108	coenzyme biosynthetic process	7.70e-03	1.00e+00	7.017	1	1	6
GO:0006474	N-terminal protein amino acid acetylation	7.70e-03	1.00e+00	7.017	1	1	6
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	7.70e-03	1.00e+00	7.017	1	1	6
GO:0021860	pyramidal neuron development	7.70e-03	1.00e+00	7.017	1	1	6
GO:0031466	Cul5-RING ubiquitin ligase complex	7.70e-03	1.00e+00	7.017	1	1	6
GO:0021695	cerebellar cortex development	7.70e-03	1.00e+00	7.017	1	1	6
GO:0030957	Tat protein binding	7.70e-03	1.00e+00	7.017	1	4	6
GO:0046134	pyrimidine nucleoside biosynthetic process	7.70e-03	1.00e+00	7.017	1	1	6
GO:0032405	MutLalpha complex binding	7.70e-03	1.00e+00	7.017	1	2	6
GO:0000028	ribosomal small subunit assembly	8.97e-03	1.00e+00	6.795	1	1	7
GO:0004596	peptide alpha-N-acetyltransferase activity	8.97e-03	1.00e+00	6.795	1	1	7
GO:0031462	Cul2-RING ubiquitin ligase complex	8.97e-03	1.00e+00	6.795	1	2	7
GO:0006475	internal protein amino acid acetylation	8.97e-03	1.00e+00	6.795	1	1	7
GO:0016018	cyclosporin A binding	8.97e-03	1.00e+00	6.795	1	1	7
GO:0030529	ribonucleoprotein complex	9.31e-03	1.00e+00	3.769	2	8	114
GO:0019058	viral life cycle	9.47e-03	1.00e+00	3.757	2	10	115
GO:0072562	blood microparticle	9.63e-03	1.00e+00	3.744	2	4	116
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	1.02e-02	1.00e+00	6.602	1	2	8
GO:0070688	MLL5-L complex	1.02e-02	1.00e+00	6.602	1	1	8
GO:0006554	lysine catabolic process	1.02e-02	1.00e+00	6.602	1	2	8
GO:0000812	Swr1 complex	1.02e-02	1.00e+00	6.602	1	3	8
GO:0045116	protein neddylation	1.02e-02	1.00e+00	6.602	1	2	8
GO:0044822	poly(A) RNA binding	1.04e-02	1.00e+00	1.850	5	50	1078
GO:0006325	chromatin organization	1.08e-02	1.00e+00	3.660	2	4	123
GO:0006260	DNA replication	1.11e-02	1.00e+00	3.636	2	12	125
GO:0014075	response to amine	1.15e-02	1.00e+00	6.432	1	1	9
GO:0015937	coenzyme A biosynthetic process	1.15e-02	1.00e+00	6.432	1	1	9
GO:0097284	hepatocyte apoptotic process	1.15e-02	1.00e+00	6.432	1	2	9
GO:0006228	UTP biosynthetic process	1.15e-02	1.00e+00	6.432	1	1	9
GO:0000075	cell cycle checkpoint	1.15e-02	1.00e+00	6.432	1	2	9
GO:0031000	response to caffeine	1.15e-02	1.00e+00	6.432	1	2	9
GO:0000790	nuclear chromatin	1.25e-02	1.00e+00	3.547	2	7	133
GO:0016407	acetyltransferase activity	1.28e-02	1.00e+00	6.280	1	1	10
GO:0008080	N-acetyltransferase activity	1.28e-02	1.00e+00	6.280	1	1	10
GO:0015939	pantothenate metabolic process	1.28e-02	1.00e+00	6.280	1	1	10
GO:0021756	striatum development	1.28e-02	1.00e+00	6.280	1	1	10
GO:0010569	regulation of double-strand break repair via homologous recombination	1.41e-02	1.00e+00	6.143	1	1	11
GO:0031571	mitotic G1 DNA damage checkpoint	1.41e-02	1.00e+00	6.143	1	3	11
GO:0042551	neuron maturation	1.41e-02	1.00e+00	6.143	1	2	11
GO:0045651	positive regulation of macrophage differentiation	1.41e-02	1.00e+00	6.143	1	2	11
GO:0045120	pronucleus	1.41e-02	1.00e+00	6.143	1	1	11
GO:0035458	cellular response to interferon-beta	1.41e-02	1.00e+00	6.143	1	2	11
GO:0070935	3'-UTR-mediated mRNA stabilization	1.53e-02	1.00e+00	6.017	1	2	12
GO:0043968	histone H2A acetylation	1.53e-02	1.00e+00	6.017	1	3	12
GO:0051146	striated muscle cell differentiation	1.53e-02	1.00e+00	6.017	1	1	12
GO:0021794	thalamus development	1.53e-02	1.00e+00	6.017	1	1	12
GO:0005838	proteasome regulatory particle	1.53e-02	1.00e+00	6.017	1	7	12
GO:0032479	regulation of type I interferon production	1.66e-02	1.00e+00	5.902	1	2	13
GO:0005662	DNA replication factor A complex	1.66e-02	1.00e+00	5.902	1	3	13
GO:0045780	positive regulation of bone resorption	1.66e-02	1.00e+00	5.902	1	1	13
GO:0000738	DNA catabolic process, exonucleolytic	1.66e-02	1.00e+00	5.902	1	2	13
GO:0008266	poly(U) RNA binding	1.66e-02	1.00e+00	5.902	1	1	13
GO:0031011	Ino80 complex	1.79e-02	1.00e+00	5.795	1	3	14
GO:0000398	mRNA splicing, via spliceosome	1.88e-02	1.00e+00	3.236	2	12	165
GO:0045445	myoblast differentiation	1.91e-02	1.00e+00	5.695	1	2	15
GO:0035066	positive regulation of histone acetylation	1.91e-02	1.00e+00	5.695	1	1	15
GO:0016514	SWI/SNF complex	1.91e-02	1.00e+00	5.695	1	3	15
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.95e-02	1.00e+00	3.210	2	5	168
GO:0050998	nitric-oxide synthase binding	2.04e-02	1.00e+00	5.602	1	1	16
GO:0006103	2-oxoglutarate metabolic process	2.04e-02	1.00e+00	5.602	1	1	16
GO:0008408	3'-5' exonuclease activity	2.04e-02	1.00e+00	5.602	1	2	16
GO:0010243	response to organonitrogen compound	2.17e-02	1.00e+00	5.515	1	2	17
GO:0045070	positive regulation of viral genome replication	2.17e-02	1.00e+00	5.515	1	1	17
GO:0075733	intracellular transport of virus	2.17e-02	1.00e+00	5.515	1	2	17
GO:0022624	proteasome accessory complex	2.17e-02	1.00e+00	5.515	1	9	17
GO:0071392	cellular response to estradiol stimulus	2.29e-02	1.00e+00	5.432	1	1	18
GO:0006541	glutamine metabolic process	2.29e-02	1.00e+00	5.432	1	1	18
GO:0035861	site of double-strand break	2.29e-02	1.00e+00	5.432	1	1	18
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	2.42e-02	1.00e+00	5.354	1	1	19
GO:0048863	stem cell differentiation	2.42e-02	1.00e+00	5.354	1	1	19
GO:0003678	DNA helicase activity	2.42e-02	1.00e+00	5.354	1	3	19
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	2.54e-02	1.00e+00	5.280	1	2	20
GO:0005719	nuclear euchromatin	2.54e-02	1.00e+00	5.280	1	2	20
GO:0000718	nucleotide-excision repair, DNA damage removal	2.67e-02	1.00e+00	5.210	1	5	21
GO:0071364	cellular response to epidermal growth factor stimulus	2.67e-02	1.00e+00	5.210	1	1	21
GO:0030316	osteoclast differentiation	2.79e-02	1.00e+00	5.143	1	2	22
GO:0006297	nucleotide-excision repair, DNA gap filling	2.79e-02	1.00e+00	5.143	1	5	22
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	2.79e-02	1.00e+00	5.143	1	3	22
GO:0033574	response to testosterone	2.79e-02	1.00e+00	5.143	1	2	22
GO:0032201	telomere maintenance via semi-conservative replication	2.79e-02	1.00e+00	5.143	1	7	22
GO:0030863	cortical cytoskeleton	2.79e-02	1.00e+00	5.143	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	2.79e-02	1.00e+00	5.143	1	4	22
GO:0007052	mitotic spindle organization	2.79e-02	1.00e+00	5.143	1	2	22
GO:0031463	Cul3-RING ubiquitin ligase complex	2.92e-02	1.00e+00	5.079	1	2	23
GO:0043236	laminin binding	2.92e-02	1.00e+00	5.079	1	1	23
GO:0006513	protein monoubiquitination	2.92e-02	1.00e+00	5.079	1	1	23
GO:0045879	negative regulation of smoothened signaling pathway	2.92e-02	1.00e+00	5.079	1	1	23
GO:0006206	pyrimidine nucleobase metabolic process	3.04e-02	1.00e+00	5.017	1	2	24
GO:0006611	protein export from nucleus	3.17e-02	1.00e+00	4.958	1	4	25
GO:0017144	drug metabolic process	3.17e-02	1.00e+00	4.958	1	1	25
GO:0000722	telomere maintenance via recombination	3.29e-02	1.00e+00	4.902	1	7	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	3.29e-02	1.00e+00	4.902	1	2	26
GO:0005622	intracellular	3.37e-02	1.00e+00	2.782	2	5	226
GO:0004003	ATP-dependent DNA helicase activity	3.42e-02	1.00e+00	4.847	1	3	27
GO:0048565	digestive tract development	3.42e-02	1.00e+00	4.847	1	1	27
GO:0071339	MLL1 complex	3.42e-02	1.00e+00	4.847	1	3	27
GO:0043967	histone H4 acetylation	3.54e-02	1.00e+00	4.795	1	3	28
GO:0019894	kinesin binding	3.54e-02	1.00e+00	4.795	1	1	28
GO:0006099	tricarboxylic acid cycle	3.67e-02	1.00e+00	4.744	1	3	29
GO:0019005	SCF ubiquitin ligase complex	3.67e-02	1.00e+00	4.744	1	1	29
GO:0003730	mRNA 3'-UTR binding	3.67e-02	1.00e+00	4.744	1	2	29
GO:0003713	transcription coactivator activity	3.74e-02	1.00e+00	2.701	2	10	239
GO:0007346	regulation of mitotic cell cycle	3.79e-02	1.00e+00	4.695	1	3	30
GO:0006271	DNA strand elongation involved in DNA replication	3.92e-02	1.00e+00	4.648	1	9	31
GO:0007093	mitotic cell cycle checkpoint	3.92e-02	1.00e+00	4.648	1	2	31
GO:0050661	NADP binding	4.04e-02	1.00e+00	4.602	1	1	32
GO:0051219	phosphoprotein binding	4.04e-02	1.00e+00	4.602	1	3	32
GO:0034644	cellular response to UV	4.04e-02	1.00e+00	4.602	1	5	32
GO:0033572	transferrin transport	4.04e-02	1.00e+00	4.602	1	6	32
GO:0031072	heat shock protein binding	4.16e-02	1.00e+00	4.558	1	2	33
GO:0000413	protein peptidyl-prolyl isomerization	4.29e-02	1.00e+00	4.515	1	1	34
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	4.29e-02	1.00e+00	4.515	1	1	34
GO:0034332	adherens junction organization	4.53e-02	1.00e+00	4.432	1	1	36
GO:0051402	neuron apoptotic process	4.53e-02	1.00e+00	4.432	1	2	36
GO:0001895	retina homeostasis	4.53e-02	1.00e+00	4.432	1	1	36
GO:0001102	RNA polymerase II activating transcription factor binding	4.66e-02	1.00e+00	4.393	1	4	37
GO:0051084	'de novo' posttranslational protein folding	4.66e-02	1.00e+00	4.393	1	4	37
GO:0018107	peptidyl-threonine phosphorylation	4.66e-02	1.00e+00	4.393	1	1	37
GO:0000166	nucleotide binding	4.72e-02	1.00e+00	2.515	2	6	272
GO:0005975	carbohydrate metabolic process	4.78e-02	1.00e+00	2.504	2	5	274
GO:0070527	platelet aggregation	4.78e-02	1.00e+00	4.354	1	2	38
GO:0021766	hippocampus development	4.90e-02	1.00e+00	4.317	1	4	39
GO:0031490	chromatin DNA binding	4.90e-02	1.00e+00	4.317	1	2	39
GO:0006284	base-excision repair	4.90e-02	1.00e+00	4.317	1	7	39
GO:0006096	glycolytic process	4.90e-02	1.00e+00	4.317	1	4	39
GO:0022627	cytosolic small ribosomal subunit	4.90e-02	1.00e+00	4.317	1	3	39
GO:0032092	positive regulation of protein binding	4.90e-02	1.00e+00	4.317	1	3	39
GO:0007595	lactation	4.90e-02	1.00e+00	4.317	1	2	39
GO:0000781	chromosome, telomeric region	5.03e-02	1.00e+00	4.280	1	2	40
GO:0043195	terminal bouton	5.15e-02	1.00e+00	4.245	1	1	41
GO:0019899	enzyme binding	5.23e-02	1.00e+00	2.432	2	11	288
GO:0035914	skeletal muscle cell differentiation	5.27e-02	1.00e+00	4.210	1	1	42
GO:0032508	DNA duplex unwinding	5.27e-02	1.00e+00	4.210	1	4	42
GO:0014070	response to organic cyclic compound	5.39e-02	1.00e+00	4.176	1	3	43
GO:0007286	spermatid development	5.51e-02	1.00e+00	4.143	1	1	44
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	5.51e-02	1.00e+00	4.143	1	2	44
GO:0021762	substantia nigra development	5.76e-02	1.00e+00	4.079	1	1	46
GO:0001047	core promoter binding	5.76e-02	1.00e+00	4.079	1	2	46
GO:0006283	transcription-coupled nucleotide-excision repair	5.76e-02	1.00e+00	4.079	1	8	46
GO:0019003	GDP binding	6.00e-02	1.00e+00	4.017	1	2	48
GO:0031100	organ regeneration	6.24e-02	1.00e+00	3.958	1	4	50
GO:0035690	cellular response to drug	6.24e-02	1.00e+00	3.958	1	2	50
GO:0006091	generation of precursor metabolites and energy	6.36e-02	1.00e+00	3.930	1	3	51
GO:0005905	coated pit	6.36e-02	1.00e+00	3.930	1	2	51
GO:0040008	regulation of growth	6.36e-02	1.00e+00	3.930	1	3	51
GO:0003725	double-stranded RNA binding	6.73e-02	1.00e+00	3.847	1	6	54
GO:0090305	nucleic acid phosphodiester bond hydrolysis	6.73e-02	1.00e+00	3.847	1	2	54
GO:0019900	kinase binding	6.73e-02	1.00e+00	3.847	1	1	54
GO:0050680	negative regulation of epithelial cell proliferation	6.73e-02	1.00e+00	3.847	1	1	54
GO:0006879	cellular iron ion homeostasis	7.09e-02	1.00e+00	3.769	1	5	57
GO:0000724	double-strand break repair via homologous recombination	7.09e-02	1.00e+00	3.769	1	6	57
GO:0051087	chaperone binding	7.33e-02	1.00e+00	3.719	1	6	59
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	7.33e-02	1.00e+00	3.719	1	4	59
GO:0045216	cell-cell junction organization	7.33e-02	1.00e+00	3.719	1	2	59
GO:0000723	telomere maintenance	7.33e-02	1.00e+00	3.719	1	8	59
GO:0005643	nuclear pore	7.33e-02	1.00e+00	3.719	1	4	59
GO:0031966	mitochondrial membrane	7.33e-02	1.00e+00	3.719	1	1	59
GO:0003723	RNA binding	7.55e-02	1.00e+00	2.130	2	19	355
GO:0032481	positive regulation of type I interferon production	7.57e-02	1.00e+00	3.671	1	6	61
GO:0006302	double-strand break repair	7.69e-02	1.00e+00	3.648	1	8	62
GO:0019903	protein phosphatase binding	7.81e-02	1.00e+00	3.625	1	4	63
GO:0042995	cell projection	7.81e-02	1.00e+00	3.625	1	6	63
GO:0006469	negative regulation of protein kinase activity	8.04e-02	1.00e+00	3.580	1	2	65
GO:0001558	regulation of cell growth	8.16e-02	1.00e+00	3.558	1	4	66
GO:0006289	nucleotide-excision repair	8.52e-02	1.00e+00	3.494	1	12	69
GO:0034329	cell junction assembly	8.75e-02	1.00e+00	3.452	1	1	71
GO:0055037	recycling endosome	8.99e-02	1.00e+00	3.412	1	2	73
GO:0055086	nucleobase-containing small molecule metabolic process	8.99e-02	1.00e+00	3.412	1	5	73
GO:0006767	water-soluble vitamin metabolic process	9.22e-02	1.00e+00	3.373	1	3	75
GO:0007265	Ras protein signal transduction	9.22e-02	1.00e+00	3.373	1	3	75
GO:0031175	neuron projection development	9.22e-02	1.00e+00	3.373	1	1	75
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	9.34e-02	1.00e+00	3.354	1	3	76
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	9.46e-02	1.00e+00	3.335	1	5	77
GO:0006766	vitamin metabolic process	9.58e-02	1.00e+00	3.317	1	3	78
GO:0007565	female pregnancy	9.81e-02	1.00e+00	3.280	1	2	80
GO:0019083	viral transcription	9.93e-02	1.00e+00	3.262	1	8	81
GO:0001889	liver development	1.00e-01	1.00e+00	3.245	1	3	82
GO:0005681	spliceosomal complex	1.02e-01	1.00e+00	3.227	1	3	83
GO:0047485	protein N-terminus binding	1.05e-01	1.00e+00	3.176	1	4	86
GO:0006898	receptor-mediated endocytosis	1.05e-01	1.00e+00	3.176	1	2	86
GO:0006415	translational termination	1.06e-01	1.00e+00	3.159	1	8	87
GO:0003690	double-stranded DNA binding	1.11e-01	1.00e+00	3.094	1	4	91
GO:0006928	cellular component movement	1.12e-01	1.00e+00	3.079	1	7	92
GO:0006414	translational elongation	1.13e-01	1.00e+00	3.063	1	11	93
GO:0005200	structural constituent of cytoskeleton	1.13e-01	1.00e+00	3.063	1	7	93
GO:0051082	unfolded protein binding	1.15e-01	1.00e+00	3.032	1	6	95
GO:0001649	osteoblast differentiation	1.15e-01	1.00e+00	3.032	1	6	95
GO:0071456	cellular response to hypoxia	1.19e-01	1.00e+00	2.987	1	4	98
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.26e-01	1.00e+00	2.902	1	8	104
GO:0014069	postsynaptic density	1.28e-01	1.00e+00	2.874	1	1	106
GO:0016023	cytoplasmic membrane-bounded vesicle	1.29e-01	1.00e+00	2.861	1	3	107
GO:0045893	positive regulation of transcription, DNA-templated	1.29e-01	1.00e+00	1.674	2	17	487
GO:0044267	cellular protein metabolic process	1.32e-01	1.00e+00	1.651	2	24	495
GO:0042127	regulation of cell proliferation	1.34e-01	1.00e+00	2.808	1	4	111
GO:0015630	microtubule cytoskeleton	1.35e-01	1.00e+00	2.795	1	5	112
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.37e-01	1.00e+00	2.769	1	10	114
GO:0005819	spindle	1.37e-01	1.00e+00	2.769	1	7	114
GO:0005635	nuclear envelope	1.39e-01	1.00e+00	2.744	1	6	116
GO:0044237	cellular metabolic process	1.41e-01	1.00e+00	2.719	1	3	118
GO:0007219	Notch signaling pathway	1.49e-01	1.00e+00	2.636	1	4	125
GO:0007050	cell cycle arrest	1.50e-01	1.00e+00	2.625	1	7	126
GO:0006511	ubiquitin-dependent protein catabolic process	1.51e-01	1.00e+00	2.613	1	5	127
GO:0006413	translational initiation	1.56e-01	1.00e+00	2.569	1	12	131
GO:0031982	vesicle	1.59e-01	1.00e+00	2.536	1	10	134
GO:0003735	structural constituent of ribosome	1.67e-01	1.00e+00	2.463	1	8	141
GO:0007507	heart development	1.67e-01	1.00e+00	2.463	1	5	141
GO:0016887	ATPase activity	1.70e-01	1.00e+00	2.432	1	7	144
GO:0061024	membrane organization	1.72e-01	1.00e+00	2.412	1	5	146
GO:0046777	protein autophosphorylation	1.85e-01	1.00e+00	2.298	1	3	158
GO:0042803	protein homodimerization activity	1.87e-01	1.00e+00	1.333	2	11	617
GO:0045087	innate immune response	1.87e-01	1.00e+00	1.335	2	20	616
GO:0030424	axon	2.00e-01	1.00e+00	2.176	1	3	172
GO:0005768	endosome	2.02e-01	1.00e+00	2.159	1	5	174
GO:0004672	protein kinase activity	2.06e-01	1.00e+00	2.126	1	2	178
GO:0019904	protein domain specific binding	2.09e-01	1.00e+00	2.102	1	6	181
GO:0009897	external side of plasma membrane	2.11e-01	1.00e+00	2.086	1	4	183
GO:0032403	protein complex binding	2.13e-01	1.00e+00	2.071	1	7	185
GO:0003924	GTPase activity	2.31e-01	1.00e+00	1.937	1	9	203
GO:0006184	GTP catabolic process	2.48e-01	1.00e+00	1.821	1	9	220
GO:0005524	ATP binding	2.51e-01	1.00e+00	0.784	3	46	1354
GO:0007067	mitotic nuclear division	2.59e-01	1.00e+00	1.750	1	13	231
GO:0008380	RNA splicing	2.60e-01	1.00e+00	1.744	1	13	232
GO:0005759	mitochondrial matrix	2.61e-01	1.00e+00	1.738	1	12	233
GO:0006412	translation	2.63e-01	1.00e+00	1.726	1	15	235
GO:0008134	transcription factor binding	2.73e-01	1.00e+00	1.660	1	8	246
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	2.81e-01	1.00e+00	0.939	2	19	811
GO:0043025	neuronal cell body	2.81e-01	1.00e+00	1.613	1	4	254
GO:0004842	ubiquitin-protein transferase activity	2.83e-01	1.00e+00	1.602	1	4	256
GO:0046872	metal ion binding	2.90e-01	1.00e+00	0.670	3	24	1465
GO:0007264	small GTPase mediated signal transduction	3.14e-01	1.00e+00	1.422	1	3	290
GO:0016567	protein ubiquitination	3.22e-01	1.00e+00	1.378	1	5	299
GO:0006200	ATP catabolic process	3.25e-01	1.00e+00	1.359	1	14	303
GO:0005856	cytoskeleton	3.33e-01	1.00e+00	1.321	1	8	311
GO:0019901	protein kinase binding	3.40e-01	1.00e+00	1.280	1	21	320
GO:0007411	axon guidance	3.46e-01	1.00e+00	1.249	1	9	327
GO:0005525	GTP binding	3.47e-01	1.00e+00	1.245	1	11	328
GO:0043231	intracellular membrane-bounded organelle	3.51e-01	1.00e+00	1.227	1	8	332
GO:0003682	chromatin binding	3.52e-01	1.00e+00	1.218	1	12	334
GO:0005615	extracellular space	3.76e-01	1.00e+00	0.622	2	17	1010
GO:0005925	focal adhesion	3.82e-01	1.00e+00	1.071	1	18	370
GO:0007155	cell adhesion	3.94e-01	1.00e+00	1.017	1	8	384
GO:0008270	zinc ion binding	4.03e-01	1.00e+00	0.543	2	12	1067
GO:0009986	cell surface	4.23e-01	1.00e+00	0.881	1	9	422
GO:0045892	negative regulation of transcription, DNA-templated	4.25e-01	1.00e+00	0.874	1	14	424
GO:0007596	blood coagulation	4.54e-01	1.00e+00	0.744	1	14	464
GO:0055114	oxidation-reduction process	4.67e-01	1.00e+00	0.692	1	11	481
GO:0055085	transmembrane transport	4.90e-01	1.00e+00	0.596	1	8	514
GO:0048471	perinuclear region of cytoplasm	4.96e-01	1.00e+00	0.571	1	12	523
GO:0005789	endoplasmic reticulum membrane	5.66e-01	1.00e+00	0.289	1	10	636
GO:0005737	cytoplasm	6.07e-01	1.00e+00	-0.033	5	98	3976
GO:0006351	transcription, DNA-templated	6.19e-01	1.00e+00	-0.028	2	25	1585
GO:0003700	sequence-specific DNA binding transcription factor activity	6.27e-01	1.00e+00	0.055	1	11	748
GO:0007165	signal transduction	7.16e-01	1.00e+00	-0.290	1	17	950
GO:0005887	integral component of plasma membrane	7.21e-01	1.00e+00	-0.306	1	7	961
GO:0005739	mitochondrion	7.51e-01	1.00e+00	-0.429	1	24	1046
GO:0005576	extracellular region	7.52e-01	1.00e+00	-0.433	1	9	1049
GO:0006355	regulation of transcription, DNA-templated	7.70e-01	1.00e+00	-0.506	1	17	1104
GO:0003677	DNA binding	8.37e-01	1.00e+00	-0.798	1	26	1351
GO:0005886	plasma membrane	9.02e-01	1.00e+00	-0.866	2	38	2834

Wolf-ratios-Mammosphere-Adherent

meta-int-snw-6120

Interacting subnets

Genes (21)

Interactions (54)

Related GO terms (376)