meta-int-snw-5879

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
reg-snw-5925	wolf-screen-ratio-mammosphere-adherent	0.802	2.42e-06	4.82e-03	8.69e-03	8	5
int-snw-5879	wolf-screen-ratio-mammosphere-adherent	0.985	1.74e-17	8.04e-04	1.75e-02	11	11

wolf-screen-ratio-mammosphere-adherent-meta-int-snw-5879 subnetwork

Genes (16)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PPCS	79717	31	-0.569	0.802	2	-	Yes
RBX1	9978	115	1.185	0.934	148	Yes	-
PPIE	10450	31	0.567	0.802	41	-	-
RAC1	5879	2	0.103	0.985	245	Yes	-
OGDH	4967	72	0.847	0.802	126	Yes	-
TFRC	7037	31	0.730	0.802	17	-	-
RPSA	3921	120	1.327	1.151	152	Yes	-
RPS3A	6189	40	0.835	1.069	166	Yes	-
PGD	5226	89	1.201	1.106	152	Yes	-
RPA2	6118	96	1.250	1.151	76	Yes	-
RB1	5925	31	-0.102	0.802	351	-	-
ACO2	50	65	1.000	1.076	191	Yes	-
PPP2R1A	5518	19	0.644	0.985	249	Yes	-
CLTC	1213	56	0.884	1.138	247	Yes	-
RPL14	9045	49	1.250	1.113	166	Yes	-
ACTB	60	134	1.153	1.151	610	Yes	-

Interactions (24)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ACO2	50	OGDH	4967	pp	--	int.I2D: YeastLow
RB1	5925	PPCS	79717	pd	>	reg.pazar.txt: no annot
RB1	5925	RPA2	6118	pd	>	reg.pazar.txt: no annot
ACTB	60	CLTC	1213	pp	--	int.I2D: IntAct_Yeast
PGD	5226	RB1	5925	pd	<	reg.pazar.txt: no annot
RBX1	9978	PPIE	10450	pd	<>	reg.ITFP.txt: no annot
ACTB	60	RBX1	9978	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
OGDH	4967	RB1	5925	pd	<	reg.ITFP.txt: no annot
RPS3A	6189	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	PPP2R1A	5518	pp	--	int.I2D: BioGrid_Yeast
OGDH	4967	PGD	5226	pp	--	int.I2D: YeastLow
ACTB	60	RB1	5925	pd	<	reg.ITFP.txt: no annot
PPP2R1A	5518	RAC1	5879	pp	--	int.I2D: BioGrid_Fly
ACTB	60	RAC1	5879	pp	--	int.I2D: BCI, BioGrid, HPRD; int.HPRD: in vitro, in vivo
PGD	5226	PPP2R1A	5518	pp	--	int.I2D: YeastLow
ACTB	60	RPA2	6118	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
ACO2	50	PGD	5226	pp	--	int.I2D: YeastLow
ACTB	60	RPS3A	6189	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
CLTC	1213	RAC1	5879	pp	--	int.I2D: BioGrid_Fly, BIND_Fly, FlyEmbryo, IntAct_Fly
RB1	5925	TFRC	7037	pd	>	reg.ITFP.txt: no annot
ACO2	50	RAC1	5879	pp	--	int.I2D: SOURAV_MAPK_LOW, IntAct
RAC1	5879	RPS3A	6189	pp	--	int.I2D: IntAct, SOURAV_MAPK_LOW
RB1	5925	PPIE	10450	pd	>	reg.pazar.txt: no annot

Related GO terms (373)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0016032	viral process	3.68e-07	6.01e-03	3.725	7	55	540
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	3.85e-06	6.29e-02	5.162	4	10	114
GO:0070062	extracellular vesicular exosome	2.43e-05	3.97e-01	2.019	10	98	2516
GO:0005829	cytosol	2.86e-05	4.68e-01	1.993	10	125	2562
GO:0016071	mRNA metabolic process	5.43e-05	8.86e-01	4.194	4	34	223
GO:0019083	viral transcription	6.29e-05	1.00e+00	5.240	3	8	81
GO:0006415	translational termination	7.79e-05	1.00e+00	5.136	3	8	87
GO:0016070	RNA metabolic process	8.07e-05	1.00e+00	4.046	4	34	247
GO:0042470	melanosome	9.20e-05	1.00e+00	5.056	3	10	92
GO:0006414	translational elongation	9.51e-05	1.00e+00	5.040	3	11	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.33e-04	1.00e+00	4.879	3	8	104
GO:0019058	viral life cycle	1.78e-04	1.00e+00	4.734	3	10	115
GO:0036464	cytoplasmic ribonucleoprotein granule	2.06e-04	1.00e+00	6.535	2	4	22
GO:0006413	translational initiation	2.62e-04	1.00e+00	4.546	3	12	131
GO:0003735	structural constituent of ribosome	3.25e-04	1.00e+00	4.440	3	8	141
GO:0006099	tricarboxylic acid cycle	3.60e-04	1.00e+00	6.136	2	3	29
GO:0044822	poly(A) RNA binding	3.69e-04	1.00e+00	2.505	6	50	1078
GO:0005925	focal adhesion	3.81e-04	1.00e+00	3.463	4	18	370
GO:0033572	transferrin transport	4.39e-04	1.00e+00	5.994	2	6	32
GO:0022627	cytosolic small ribosomal subunit	6.54e-04	1.00e+00	5.709	2	3	39
GO:0031625	ubiquitin protein ligase binding	6.65e-04	1.00e+00	4.088	3	13	180
GO:0016020	membrane	7.56e-04	1.00e+00	2.032	7	80	1746
GO:0048532	anatomical structure arrangement	9.80e-04	1.00e+00	9.994	1	1	1
GO:0034602	oxoglutarate dehydrogenase (NAD+) activity	9.80e-04	1.00e+00	9.994	1	1	1
GO:0090230	regulation of centromere complex assembly	9.80e-04	1.00e+00	9.994	1	1	1
GO:0070262	peptidyl-serine dephosphorylation	9.80e-04	1.00e+00	9.994	1	1	1
GO:0004632	phosphopantothenate--cysteine ligase activity	9.80e-04	1.00e+00	9.994	1	1	1
GO:0019521	D-gluconate metabolic process	9.80e-04	1.00e+00	9.994	1	1	1
GO:0006091	generation of precursor metabolites and energy	1.12e-03	1.00e+00	5.322	2	3	51
GO:0044267	cellular protein metabolic process	1.14e-03	1.00e+00	3.043	4	24	495
GO:0003725	double-stranded RNA binding	1.25e-03	1.00e+00	5.240	2	6	54
GO:0006412	translation	1.44e-03	1.00e+00	3.703	3	15	235
GO:0045216	cell-cell junction organization	1.49e-03	1.00e+00	5.112	2	2	59
GO:0045252	oxoglutarate dehydrogenase complex	1.96e-03	1.00e+00	8.994	1	2	2
GO:0021831	embryonic olfactory bulb interneuron precursor migration	1.96e-03	1.00e+00	8.994	1	1	2
GO:0051538	3 iron, 4 sulfur cluster binding	1.96e-03	1.00e+00	8.994	1	1	2
GO:0051668	localization within membrane	1.96e-03	1.00e+00	8.994	1	1	2
GO:0003994	aconitate hydratase activity	1.96e-03	1.00e+00	8.994	1	1	2
GO:0097286	iron ion import	1.96e-03	1.00e+00	8.994	1	1	2
GO:0006407	rRNA export from nucleus	1.96e-03	1.00e+00	8.994	1	1	2
GO:0032707	negative regulation of interleukin-23 production	1.96e-03	1.00e+00	8.994	1	1	2
GO:0061034	olfactory bulb mitral cell layer development	1.96e-03	1.00e+00	8.994	1	1	2
GO:0051022	Rho GDP-dissociation inhibitor binding	1.96e-03	1.00e+00	8.994	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.96e-03	1.00e+00	8.994	1	1	2
GO:0004998	transferrin receptor activity	1.96e-03	1.00e+00	8.994	1	1	2
GO:0019322	pentose biosynthetic process	1.96e-03	1.00e+00	8.994	1	1	2
GO:0031134	sister chromatid biorientation	1.96e-03	1.00e+00	8.994	1	1	2
GO:0005055	laminin receptor activity	1.96e-03	1.00e+00	8.994	1	1	2
GO:0002093	auditory receptor cell morphogenesis	1.96e-03	1.00e+00	8.994	1	1	2
GO:0007070	negative regulation of transcription from RNA polymerase II promoter during mitosis	1.96e-03	1.00e+00	8.994	1	2	2
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	2.53e-03	1.00e+00	4.728	2	5	77
GO:0005515	protein binding	2.62e-03	1.00e+00	0.998	12	172	6127
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	2.94e-03	1.00e+00	8.409	1	1	3
GO:0043652	engulfment of apoptotic cell	2.94e-03	1.00e+00	8.409	1	1	3
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	2.94e-03	1.00e+00	8.409	1	1	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	2.94e-03	1.00e+00	8.409	1	1	3
GO:0071459	protein localization to chromosome, centromeric region	2.94e-03	1.00e+00	8.409	1	1	3
GO:1900126	negative regulation of hyaluronan biosynthetic process	2.94e-03	1.00e+00	8.409	1	1	3
GO:0009051	pentose-phosphate shunt, oxidative branch	2.94e-03	1.00e+00	8.409	1	1	3
GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle	2.94e-03	1.00e+00	8.409	1	1	3
GO:0071439	clathrin complex	2.94e-03	1.00e+00	8.409	1	1	3
GO:0006898	receptor-mediated endocytosis	3.14e-03	1.00e+00	4.568	2	2	86
GO:0010467	gene expression	3.43e-03	1.00e+00	2.609	4	58	669
GO:0019901	protein kinase binding	3.46e-03	1.00e+00	3.257	3	21	320
GO:0016605	PML body	3.58e-03	1.00e+00	4.471	2	5	92
GO:0006928	cellular component movement	3.58e-03	1.00e+00	4.471	2	7	92
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.92e-03	1.00e+00	7.994	1	1	4
GO:0030686	90S preribosome	3.92e-03	1.00e+00	7.994	1	1	4
GO:0071922	regulation of cohesin localization to chromatin	3.92e-03	1.00e+00	7.994	1	1	4
GO:0010310	regulation of hydrogen peroxide metabolic process	3.92e-03	1.00e+00	7.994	1	1	4
GO:0032051	clathrin light chain binding	3.92e-03	1.00e+00	7.994	1	1	4
GO:0019788	NEDD8 ligase activity	3.92e-03	1.00e+00	7.994	1	1	4
GO:0002551	mast cell chemotaxis	3.92e-03	1.00e+00	7.994	1	1	4
GO:0060263	regulation of respiratory burst	3.92e-03	1.00e+00	7.994	1	1	4
GO:0006104	succinyl-CoA metabolic process	3.92e-03	1.00e+00	7.994	1	1	4
GO:0031467	Cul7-RING ubiquitin ligase complex	3.92e-03	1.00e+00	7.994	1	1	4
GO:0043550	regulation of lipid kinase activity	3.92e-03	1.00e+00	7.994	1	1	4
GO:0035189	Rb-E2F complex	3.92e-03	1.00e+00	7.994	1	1	4
GO:0034349	glial cell apoptotic process	3.92e-03	1.00e+00	7.994	1	1	4
GO:0034088	maintenance of mitotic sister chromatid cohesion	3.92e-03	1.00e+00	7.994	1	1	4
GO:1903077	negative regulation of protein localization to plasma membrane	3.92e-03	1.00e+00	7.994	1	1	4
GO:0003723	RNA binding	4.63e-03	1.00e+00	3.108	3	19	355
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	4.89e-03	1.00e+00	7.673	1	2	5
GO:0019932	second-messenger-mediated signaling	4.89e-03	1.00e+00	7.673	1	1	5
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	4.89e-03	1.00e+00	7.673	1	1	5
GO:2000001	regulation of DNA damage checkpoint	4.89e-03	1.00e+00	7.673	1	1	5
GO:0031461	cullin-RING ubiquitin ligase complex	4.89e-03	1.00e+00	7.673	1	1	5
GO:0048667	cell morphogenesis involved in neuron differentiation	4.89e-03	1.00e+00	7.673	1	1	5
GO:0006102	isocitrate metabolic process	4.89e-03	1.00e+00	7.673	1	1	5
GO:0030891	VCB complex	4.89e-03	1.00e+00	7.673	1	2	5
GO:0000730	DNA recombinase assembly	4.89e-03	1.00e+00	7.673	1	3	5
GO:0006734	NADH metabolic process	4.89e-03	1.00e+00	7.673	1	1	5
GO:0030976	thiamine pyrophosphate binding	4.89e-03	1.00e+00	7.673	1	1	5
GO:0030529	ribonucleoprotein complex	5.44e-03	1.00e+00	4.162	2	8	114
GO:0005819	spindle	5.44e-03	1.00e+00	4.162	2	7	114
GO:0072562	blood microparticle	5.63e-03	1.00e+00	4.136	2	4	116
GO:0044237	cellular metabolic process	5.82e-03	1.00e+00	4.112	2	3	118
GO:0043353	enucleate erythrocyte differentiation	5.87e-03	1.00e+00	7.409	1	1	6
GO:0002181	cytoplasmic translation	5.87e-03	1.00e+00	7.409	1	1	6
GO:0009108	coenzyme biosynthetic process	5.87e-03	1.00e+00	7.409	1	1	6
GO:0030130	clathrin coat of trans-Golgi network vesicle	5.87e-03	1.00e+00	7.409	1	1	6
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	5.87e-03	1.00e+00	7.409	1	1	6
GO:0006101	citrate metabolic process	5.87e-03	1.00e+00	7.409	1	1	6
GO:0021860	pyramidal neuron development	5.87e-03	1.00e+00	7.409	1	1	6
GO:0030118	clathrin coat	5.87e-03	1.00e+00	7.409	1	1	6
GO:0031466	Cul5-RING ubiquitin ligase complex	5.87e-03	1.00e+00	7.409	1	1	6
GO:0048261	negative regulation of receptor-mediated endocytosis	5.87e-03	1.00e+00	7.409	1	1	6
GO:0021695	cerebellar cortex development	5.87e-03	1.00e+00	7.409	1	1	6
GO:0030957	Tat protein binding	5.87e-03	1.00e+00	7.409	1	4	6
GO:0097178	ruffle assembly	5.87e-03	1.00e+00	7.409	1	1	6
GO:0000278	mitotic cell cycle	6.36e-03	1.00e+00	2.943	3	52	398
GO:0000028	ribosomal small subunit assembly	6.84e-03	1.00e+00	7.187	1	1	7
GO:0031462	Cul2-RING ubiquitin ligase complex	6.84e-03	1.00e+00	7.187	1	2	7
GO:0030132	clathrin coat of coated pit	6.84e-03	1.00e+00	7.187	1	1	7
GO:0016018	cyclosporin A binding	6.84e-03	1.00e+00	7.187	1	1	7
GO:0031982	vesicle	7.45e-03	1.00e+00	3.928	2	10	134
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	7.82e-03	1.00e+00	6.994	1	2	8
GO:0070688	MLL5-L complex	7.82e-03	1.00e+00	6.994	1	1	8
GO:0006554	lysine catabolic process	7.82e-03	1.00e+00	6.994	1	2	8
GO:0045116	protein neddylation	7.82e-03	1.00e+00	6.994	1	2	8
GO:0021799	cerebral cortex radially oriented cell migration	7.82e-03	1.00e+00	6.994	1	1	8
GO:0061024	membrane organization	8.78e-03	1.00e+00	3.805	2	5	146
GO:0015937	coenzyme A biosynthetic process	8.79e-03	1.00e+00	6.825	1	1	9
GO:0097284	hepatocyte apoptotic process	8.79e-03	1.00e+00	6.825	1	2	9
GO:0003382	epithelial cell morphogenesis	8.79e-03	1.00e+00	6.825	1	1	9
GO:0000075	cell cycle checkpoint	8.79e-03	1.00e+00	6.825	1	2	9
GO:0006972	hyperosmotic response	8.79e-03	1.00e+00	6.825	1	1	9
GO:0006457	protein folding	9.14e-03	1.00e+00	3.775	2	8	149
GO:0000082	G1/S transition of mitotic cell cycle	9.25e-03	1.00e+00	3.766	2	33	150
GO:0007084	mitotic nuclear envelope reassembly	9.76e-03	1.00e+00	6.673	1	1	10
GO:0015939	pantothenate metabolic process	9.76e-03	1.00e+00	6.673	1	1	10
GO:0035025	positive regulation of Rho protein signal transduction	9.76e-03	1.00e+00	6.673	1	1	10
GO:0021756	striatum development	9.76e-03	1.00e+00	6.673	1	1	10
GO:0006098	pentose-phosphate shunt	1.07e-02	1.00e+00	6.535	1	3	11
GO:0060071	Wnt signaling pathway, planar cell polarity pathway	1.07e-02	1.00e+00	6.535	1	2	11
GO:0010569	regulation of double-strand break repair via homologous recombination	1.07e-02	1.00e+00	6.535	1	1	11
GO:0031571	mitotic G1 DNA damage checkpoint	1.07e-02	1.00e+00	6.535	1	3	11
GO:0042551	neuron maturation	1.07e-02	1.00e+00	6.535	1	2	11
GO:0045651	positive regulation of macrophage differentiation	1.07e-02	1.00e+00	6.535	1	2	11
GO:0010592	positive regulation of lamellipodium assembly	1.17e-02	1.00e+00	6.409	1	1	12
GO:0051146	striated muscle cell differentiation	1.17e-02	1.00e+00	6.409	1	1	12
GO:0006275	regulation of DNA replication	1.17e-02	1.00e+00	6.409	1	2	12
GO:0021794	thalamus development	1.17e-02	1.00e+00	6.409	1	1	12
GO:0030111	regulation of Wnt signaling pathway	1.17e-02	1.00e+00	6.409	1	1	12
GO:0042273	ribosomal large subunit biogenesis	1.27e-02	1.00e+00	6.294	1	4	13
GO:0005662	DNA replication factor A complex	1.27e-02	1.00e+00	6.294	1	3	13
GO:0045780	positive regulation of bone resorption	1.27e-02	1.00e+00	6.294	1	1	13
GO:0071542	dopaminergic neuron differentiation	1.27e-02	1.00e+00	6.294	1	1	13
GO:0035267	NuA4 histone acetyltransferase complex	1.36e-02	1.00e+00	6.187	1	4	14
GO:0031996	thioesterase binding	1.36e-02	1.00e+00	6.187	1	2	14
GO:0006672	ceramide metabolic process	1.46e-02	1.00e+00	6.088	1	1	15
GO:0045445	myoblast differentiation	1.46e-02	1.00e+00	6.088	1	2	15
GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	1.46e-02	1.00e+00	6.088	1	2	15
GO:0016514	SWI/SNF complex	1.46e-02	1.00e+00	6.088	1	3	15
GO:0031529	ruffle organization	1.46e-02	1.00e+00	6.088	1	1	15
GO:0048870	cell motility	1.56e-02	1.00e+00	5.994	1	1	16
GO:0050998	nitric-oxide synthase binding	1.56e-02	1.00e+00	5.994	1	1	16
GO:0006103	2-oxoglutarate metabolic process	1.56e-02	1.00e+00	5.994	1	1	16
GO:0001891	phagocytic cup	1.56e-02	1.00e+00	5.994	1	2	16
GO:0045070	positive regulation of viral genome replication	1.65e-02	1.00e+00	5.907	1	1	17
GO:0030742	GTP-dependent protein binding	1.65e-02	1.00e+00	5.907	1	1	17
GO:0051894	positive regulation of focal adhesion assembly	1.75e-02	1.00e+00	5.825	1	1	18
GO:0035861	site of double-strand break	1.75e-02	1.00e+00	5.825	1	1	18
GO:0090023	positive regulation of neutrophil chemotaxis	1.75e-02	1.00e+00	5.825	1	1	18
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	1.85e-02	1.00e+00	5.747	1	1	19
GO:0071526	semaphorin-plexin signaling pathway	1.85e-02	1.00e+00	5.747	1	1	19
GO:0045453	bone resorption	1.85e-02	1.00e+00	5.747	1	2	19
GO:0005654	nucleoplasm	1.91e-02	1.00e+00	1.898	4	83	1095
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	1.94e-02	1.00e+00	5.673	1	2	20
GO:0019897	extrinsic component of plasma membrane	1.94e-02	1.00e+00	5.673	1	2	20
GO:0008601	protein phosphatase type 2A regulator activity	1.94e-02	1.00e+00	5.673	1	3	20
GO:0006298	mismatch repair	1.94e-02	1.00e+00	5.673	1	6	20
GO:0000159	protein phosphatase type 2A complex	1.94e-02	1.00e+00	5.673	1	2	20
GO:0045595	regulation of cell differentiation	2.04e-02	1.00e+00	5.602	1	1	21
GO:0000718	nucleotide-excision repair, DNA damage removal	2.04e-02	1.00e+00	5.602	1	5	21
GO:0090103	cochlea morphogenesis	2.04e-02	1.00e+00	5.602	1	2	21
GO:0005759	mitochondrial matrix	2.13e-02	1.00e+00	3.130	2	12	233
GO:0030316	osteoclast differentiation	2.14e-02	1.00e+00	5.535	1	2	22
GO:0030041	actin filament polymerization	2.14e-02	1.00e+00	5.535	1	3	22
GO:0006297	nucleotide-excision repair, DNA gap filling	2.14e-02	1.00e+00	5.535	1	5	22
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	2.14e-02	1.00e+00	5.535	1	3	22
GO:0032201	telomere maintenance via semi-conservative replication	2.14e-02	1.00e+00	5.535	1	7	22
GO:0030863	cortical cytoskeleton	2.14e-02	1.00e+00	5.535	1	1	22
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	2.23e-02	1.00e+00	5.471	1	2	23
GO:0031463	Cul3-RING ubiquitin ligase complex	2.23e-02	1.00e+00	5.471	1	2	23
GO:0043236	laminin binding	2.23e-02	1.00e+00	5.471	1	1	23
GO:0006513	protein monoubiquitination	2.23e-02	1.00e+00	5.471	1	1	23
GO:0043044	ATP-dependent chromatin remodeling	2.23e-02	1.00e+00	5.471	1	4	23
GO:0045879	negative regulation of smoothened signaling pathway	2.23e-02	1.00e+00	5.471	1	1	23
GO:0000722	telomere maintenance via recombination	2.52e-02	1.00e+00	5.294	1	7	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	2.52e-02	1.00e+00	5.294	1	2	26
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	2.52e-02	1.00e+00	5.294	1	1	26
GO:0000188	inactivation of MAPK activity	2.62e-02	1.00e+00	5.240	1	1	27
GO:0048565	digestive tract development	2.62e-02	1.00e+00	5.240	1	1	27
GO:0006281	DNA repair	2.69e-02	1.00e+00	2.950	2	22	264
GO:0003823	antigen binding	2.71e-02	1.00e+00	5.187	1	1	28
GO:0010033	response to organic substance	2.71e-02	1.00e+00	5.187	1	2	28
GO:0050690	regulation of defense response to virus by virus	2.71e-02	1.00e+00	5.187	1	1	28
GO:0043022	ribosome binding	2.71e-02	1.00e+00	5.187	1	3	28
GO:0031492	nucleosomal DNA binding	2.71e-02	1.00e+00	5.187	1	4	28
GO:0019894	kinesin binding	2.71e-02	1.00e+00	5.187	1	1	28
GO:0019005	SCF ubiquitin ligase complex	2.81e-02	1.00e+00	5.136	1	1	29
GO:0030669	clathrin-coated endocytic vesicle membrane	2.81e-02	1.00e+00	5.136	1	1	29
GO:0007346	regulation of mitotic cell cycle	2.90e-02	1.00e+00	5.088	1	3	30
GO:0031623	receptor internalization	3.00e-02	1.00e+00	5.040	1	1	31
GO:0030032	lamellipodium assembly	3.00e-02	1.00e+00	5.040	1	2	31
GO:0006271	DNA strand elongation involved in DNA replication	3.00e-02	1.00e+00	5.040	1	9	31
GO:0007093	mitotic cell cycle checkpoint	3.00e-02	1.00e+00	5.040	1	2	31
GO:0048813	dendrite morphogenesis	3.00e-02	1.00e+00	5.040	1	1	31
GO:0050661	NADP binding	3.09e-02	1.00e+00	4.994	1	1	32
GO:0051219	phosphoprotein binding	3.09e-02	1.00e+00	4.994	1	3	32
GO:0019899	enzyme binding	3.16e-02	1.00e+00	2.825	2	11	288
GO:0031072	heat shock protein binding	3.19e-02	1.00e+00	4.950	1	2	33
GO:0000413	protein peptidyl-prolyl isomerization	3.28e-02	1.00e+00	4.907	1	1	34
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	3.28e-02	1.00e+00	4.907	1	1	34
GO:0044281	small molecule metabolic process	3.32e-02	1.00e+00	1.656	4	57	1295
GO:0010811	positive regulation of cell-substrate adhesion	3.38e-02	1.00e+00	4.865	1	1	35
GO:0043234	protein complex	3.41e-02	1.00e+00	2.766	2	17	300
GO:0032588	trans-Golgi network membrane	3.47e-02	1.00e+00	4.825	1	1	36
GO:0034332	adherens junction organization	3.47e-02	1.00e+00	4.825	1	1	36
GO:0051402	neuron apoptotic process	3.47e-02	1.00e+00	4.825	1	2	36
GO:0034446	substrate adhesion-dependent cell spreading	3.47e-02	1.00e+00	4.825	1	2	36
GO:0001895	retina homeostasis	3.47e-02	1.00e+00	4.825	1	1	36
GO:0030838	positive regulation of actin filament polymerization	3.47e-02	1.00e+00	4.825	1	2	36
GO:0001102	RNA polymerase II activating transcription factor binding	3.57e-02	1.00e+00	4.785	1	4	37
GO:0051084	'de novo' posttranslational protein folding	3.57e-02	1.00e+00	4.785	1	4	37
GO:0051539	4 iron, 4 sulfur cluster binding	3.57e-02	1.00e+00	4.785	1	3	37
GO:0045740	positive regulation of DNA replication	3.66e-02	1.00e+00	4.747	1	2	38
GO:0070527	platelet aggregation	3.66e-02	1.00e+00	4.747	1	2	38
GO:0050681	androgen receptor binding	3.66e-02	1.00e+00	4.747	1	4	38
GO:0021766	hippocampus development	3.76e-02	1.00e+00	4.709	1	4	39
GO:0006284	base-excision repair	3.76e-02	1.00e+00	4.709	1	7	39
GO:0006096	glycolytic process	3.76e-02	1.00e+00	4.709	1	4	39
GO:0051496	positive regulation of stress fiber assembly	3.76e-02	1.00e+00	4.709	1	2	39
GO:0000781	chromosome, telomeric region	3.85e-02	1.00e+00	4.673	1	2	40
GO:0072659	protein localization to plasma membrane	3.95e-02	1.00e+00	4.637	1	1	41
GO:0030521	androgen receptor signaling pathway	3.95e-02	1.00e+00	4.637	1	2	41
GO:0007411	axon guidance	3.99e-02	1.00e+00	2.641	2	9	327
GO:0004722	protein serine/threonine phosphatase activity	4.04e-02	1.00e+00	4.602	1	1	42
GO:0035914	skeletal muscle cell differentiation	4.04e-02	1.00e+00	4.602	1	1	42
GO:0030155	regulation of cell adhesion	4.04e-02	1.00e+00	4.602	1	3	42
GO:0006892	post-Golgi vesicle-mediated transport	4.23e-02	1.00e+00	4.535	1	2	44
GO:0021762	substantia nigra development	4.42e-02	1.00e+00	4.471	1	1	46
GO:0030136	clathrin-coated vesicle	4.42e-02	1.00e+00	4.471	1	1	46
GO:0001047	core promoter binding	4.42e-02	1.00e+00	4.471	1	2	46
GO:0006283	transcription-coupled nucleotide-excision repair	4.42e-02	1.00e+00	4.471	1	8	46
GO:0005884	actin filament	4.42e-02	1.00e+00	4.471	1	2	46
GO:0022625	cytosolic large ribosomal subunit	4.70e-02	1.00e+00	4.380	1	5	49
GO:0005905	coated pit	4.89e-02	1.00e+00	4.322	1	2	51
GO:0040008	regulation of growth	4.89e-02	1.00e+00	4.322	1	3	51
GO:0003684	damaged DNA binding	4.89e-02	1.00e+00	4.322	1	11	51
GO:0000775	chromosome, centromeric region	4.98e-02	1.00e+00	4.294	1	2	52
GO:0030334	regulation of cell migration	4.98e-02	1.00e+00	4.294	1	2	52
GO:0009611	response to wounding	5.07e-02	1.00e+00	4.267	1	1	53
GO:0019900	kinase binding	5.17e-02	1.00e+00	4.240	1	1	54
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	5.17e-02	1.00e+00	4.240	1	5	54
GO:0050680	negative regulation of epithelial cell proliferation	5.17e-02	1.00e+00	4.240	1	1	54
GO:0007155	cell adhesion	5.33e-02	1.00e+00	2.409	2	8	384
GO:0006879	cellular iron ion homeostasis	5.45e-02	1.00e+00	4.162	1	5	57
GO:0000724	double-strand break repair via homologous recombination	5.45e-02	1.00e+00	4.162	1	6	57
GO:0051087	chaperone binding	5.63e-02	1.00e+00	4.112	1	6	59
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	5.63e-02	1.00e+00	4.112	1	4	59
GO:0000723	telomere maintenance	5.63e-02	1.00e+00	4.112	1	8	59
GO:0031966	mitochondrial membrane	5.63e-02	1.00e+00	4.112	1	1	59
GO:0006302	double-strand break repair	5.91e-02	1.00e+00	4.040	1	8	62
GO:0019903	protein phosphatase binding	6.00e-02	1.00e+00	4.017	1	4	63
GO:0007059	chromosome segregation	6.10e-02	1.00e+00	3.994	1	3	64
GO:0006469	negative regulation of protein kinase activity	6.19e-02	1.00e+00	3.972	1	2	65
GO:0001558	regulation of cell growth	6.28e-02	1.00e+00	3.950	1	4	66
GO:0031295	T cell costimulation	6.37e-02	1.00e+00	3.928	1	1	67
GO:0006338	chromatin remodeling	6.46e-02	1.00e+00	3.907	1	4	68
GO:0006289	nucleotide-excision repair	6.56e-02	1.00e+00	3.886	1	12	69
GO:0003697	single-stranded DNA binding	6.56e-02	1.00e+00	3.886	1	9	69
GO:0034329	cell junction assembly	6.74e-02	1.00e+00	3.845	1	1	71
GO:0032587	ruffle membrane	6.83e-02	1.00e+00	3.825	1	4	72
GO:0005634	nucleus	6.90e-02	1.00e+00	0.757	8	131	4828
GO:0055037	recycling endosome	6.92e-02	1.00e+00	3.805	1	2	73
GO:0000785	chromatin	6.92e-02	1.00e+00	3.805	1	5	73
GO:0006767	water-soluble vitamin metabolic process	7.11e-02	1.00e+00	3.766	1	3	75
GO:0007265	Ras protein signal transduction	7.11e-02	1.00e+00	3.766	1	3	75
GO:0031175	neuron projection development	7.11e-02	1.00e+00	3.766	1	1	75
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	7.20e-02	1.00e+00	3.747	1	3	76
GO:0017137	Rab GTPase binding	7.38e-02	1.00e+00	3.709	1	2	78
GO:0006766	vitamin metabolic process	7.38e-02	1.00e+00	3.709	1	3	78
GO:0007596	blood coagulation	7.44e-02	1.00e+00	2.136	2	14	464
GO:0071013	catalytic step 2 spliceosome	7.47e-02	1.00e+00	3.691	1	7	79
GO:0005739	mitochondrion	7.87e-02	1.00e+00	1.549	3	24	1046
GO:0047485	protein N-terminus binding	8.11e-02	1.00e+00	3.568	1	4	86
GO:0009653	anatomical structure morphogenesis	8.20e-02	1.00e+00	3.551	1	2	87
GO:0042802	identical protein binding	8.21e-02	1.00e+00	2.055	2	18	491
GO:0007160	cell-matrix adhesion	8.29e-02	1.00e+00	3.535	1	3	88
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	8.65e-02	1.00e+00	3.471	1	4	92
GO:0005200	structural constituent of cytoskeleton	8.74e-02	1.00e+00	3.455	1	7	93
GO:0001649	osteoblast differentiation	8.92e-02	1.00e+00	3.425	1	6	95
GO:0006364	rRNA processing	9.01e-02	1.00e+00	3.409	1	5	96
GO:0071456	cellular response to hypoxia	9.19e-02	1.00e+00	3.380	1	4	98
GO:0006470	protein dephosphorylation	9.28e-02	1.00e+00	3.365	1	1	99
GO:0014069	postsynaptic density	9.90e-02	1.00e+00	3.267	1	1	106
GO:0016023	cytoplasmic membrane-bounded vesicle	9.99e-02	1.00e+00	3.253	1	3	107
GO:0001934	positive regulation of protein phosphorylation	1.01e-01	1.00e+00	3.240	1	5	108
GO:0042127	regulation of cell proliferation	1.03e-01	1.00e+00	3.200	1	4	111
GO:0006461	protein complex assembly	1.03e-01	1.00e+00	3.200	1	6	111
GO:0015630	microtubule cytoskeleton	1.04e-01	1.00e+00	3.187	1	5	112
GO:0030308	negative regulation of cell growth	1.05e-01	1.00e+00	3.174	1	6	113
GO:0097190	apoptotic signaling pathway	1.08e-01	1.00e+00	3.136	1	4	116
GO:0005802	trans-Golgi network	1.08e-01	1.00e+00	3.136	1	2	116
GO:0006325	chromatin organization	1.14e-01	1.00e+00	3.052	1	4	123
GO:0007219	Notch signaling pathway	1.16e-01	1.00e+00	3.029	1	4	125
GO:0006260	DNA replication	1.16e-01	1.00e+00	3.029	1	12	125
GO:0007050	cell cycle arrest	1.17e-01	1.00e+00	3.017	1	7	126
GO:0005506	iron ion binding	1.18e-01	1.00e+00	3.006	1	3	127
GO:0030036	actin cytoskeleton organization	1.19e-01	1.00e+00	2.983	1	5	129
GO:0030027	lamellipodium	1.20e-01	1.00e+00	2.972	1	4	130
GO:0045087	innate immune response	1.21e-01	1.00e+00	1.728	2	20	616
GO:0000790	nuclear chromatin	1.23e-01	1.00e+00	2.939	1	7	133
GO:0000086	G2/M transition of mitotic cell cycle	1.26e-01	1.00e+00	2.896	1	7	137
GO:0005198	structural molecule activity	1.45e-01	1.00e+00	2.682	1	4	159
GO:0008543	fibroblast growth factor receptor signaling pathway	1.45e-01	1.00e+00	2.682	1	4	159
GO:0000398	mRNA splicing, via spliceosome	1.50e-01	1.00e+00	2.628	1	12	165
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.53e-01	1.00e+00	2.602	1	5	168
GO:0038095	Fc-epsilon receptor signaling pathway	1.55e-01	1.00e+00	2.577	1	7	171
GO:0030424	axon	1.56e-01	1.00e+00	2.568	1	3	172
GO:0006886	intracellular protein transport	1.57e-01	1.00e+00	2.560	1	4	173
GO:0005768	endosome	1.58e-01	1.00e+00	2.551	1	5	174
GO:0034641	cellular nitrogen compound metabolic process	1.60e-01	1.00e+00	2.527	1	25	177
GO:0009897	external side of plasma membrane	1.65e-01	1.00e+00	2.479	1	4	183
GO:0032403	protein complex binding	1.67e-01	1.00e+00	2.463	1	7	185
GO:0003924	GTPase activity	1.82e-01	1.00e+00	2.329	1	9	203
GO:0030168	platelet activation	1.83e-01	1.00e+00	2.315	1	9	205
GO:0006184	GTP catabolic process	1.95e-01	1.00e+00	2.213	1	9	220
GO:0007067	mitotic nuclear division	2.04e-01	1.00e+00	2.143	1	13	231
GO:0008380	RNA splicing	2.05e-01	1.00e+00	2.136	1	13	232
GO:0003713	transcription coactivator activity	2.10e-01	1.00e+00	2.094	1	10	239
GO:0008134	transcription factor binding	2.16e-01	1.00e+00	2.052	1	8	246
GO:0004842	ubiquitin-protein transferase activity	2.24e-01	1.00e+00	1.994	1	4	256
GO:0000166	nucleotide binding	2.36e-01	1.00e+00	1.907	1	6	272
GO:0005975	carbohydrate metabolic process	2.37e-01	1.00e+00	1.896	1	5	274
GO:0048011	neurotrophin TRK receptor signaling pathway	2.37e-01	1.00e+00	1.902	1	6	273
GO:0043065	positive regulation of apoptotic process	2.37e-01	1.00e+00	1.896	1	8	274
GO:0006954	inflammatory response	2.49e-01	1.00e+00	1.820	1	6	289
GO:0007264	small GTPase mediated signal transduction	2.49e-01	1.00e+00	1.815	1	3	290
GO:0016567	protein ubiquitination	2.56e-01	1.00e+00	1.770	1	5	299
GO:0005615	extracellular space	2.60e-01	1.00e+00	1.014	2	17	1010
GO:0005856	cytoskeleton	2.65e-01	1.00e+00	1.714	1	8	311
GO:0035556	intracellular signal transduction	2.69e-01	1.00e+00	1.686	1	6	317
GO:0030154	cell differentiation	2.75e-01	1.00e+00	1.650	1	5	325
GO:0005525	GTP binding	2.77e-01	1.00e+00	1.637	1	11	328
GO:0008283	cell proliferation	2.80e-01	1.00e+00	1.624	1	12	331
GO:0043231	intracellular membrane-bounded organelle	2.80e-01	1.00e+00	1.619	1	8	332
GO:0006355	regulation of transcription, DNA-templated	2.95e-01	1.00e+00	0.886	2	17	1104
GO:0005886	plasma membrane	2.98e-01	1.00e+00	0.526	4	38	2834
GO:0007186	G-protein coupled receptor signaling pathway	3.05e-01	1.00e+00	1.475	1	5	367
GO:0046982	protein heterodimerization activity	3.27e-01	1.00e+00	1.354	1	11	399
GO:0000139	Golgi membrane	3.33e-01	1.00e+00	1.322	1	2	408
GO:0009986	cell surface	3.43e-01	1.00e+00	1.273	1	9	422
GO:0045892	negative regulation of transcription, DNA-templated	3.44e-01	1.00e+00	1.267	1	14	424
GO:0005737	cytoplasm	3.47e-01	1.00e+00	0.359	5	98	3976
GO:0043066	negative regulation of apoptotic process	3.50e-01	1.00e+00	1.236	1	30	433
GO:0055114	oxidation-reduction process	3.81e-01	1.00e+00	1.085	1	11	481
GO:0045893	positive regulation of transcription, DNA-templated	3.84e-01	1.00e+00	1.067	1	17	487
GO:0055085	transmembrane transport	4.01e-01	1.00e+00	0.989	1	8	514
GO:0048471	perinuclear region of cytoplasm	4.06e-01	1.00e+00	0.964	1	12	523
GO:0006915	apoptotic process	4.35e-01	1.00e+00	0.837	1	34	571
GO:0005730	nucleolus	5.03e-01	1.00e+00	0.277	2	70	1684
GO:0003700	sequence-specific DNA binding transcription factor activity	5.28e-01	1.00e+00	0.448	1	11	748
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	5.58e-01	1.00e+00	0.331	1	19	811
GO:0005887	integral component of plasma membrane	6.21e-01	1.00e+00	0.086	1	7	961
GO:0005576	extracellular region	6.55e-01	1.00e+00	-0.040	1	9	1049
GO:0008270	zinc ion binding	6.61e-01	1.00e+00	-0.065	1	12	1067
GO:0003677	DNA binding	7.49e-01	1.00e+00	-0.405	1	26	1351
GO:0005524	ATP binding	7.50e-01	1.00e+00	-0.409	1	46	1354
GO:0046872	metal ion binding	7.78e-01	1.00e+00	-0.522	1	24	1465
GO:0006351	transcription, DNA-templated	8.05e-01	1.00e+00	-0.636	1	25	1585

Wolf-ratios-Mammosphere-Adherent

meta-int-snw-5879

Interacting subnets

Genes (16)

Interactions (24)

Related GO terms (373)