meta-int-snw-51004

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
reg-snw-11277	wolf-screen-ratio-mammosphere-adherent	0.882	1.09e-07	9.11e-04	1.96e-03	10	9
int-snw-51004	wolf-screen-ratio-mammosphere-adherent	0.960	1.71e-16	1.42e-03	2.67e-02	9	6

wolf-screen-ratio-mammosphere-adherent-meta-int-snw-51004 subnetwork

Genes (16)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PSMB1	5689	61	0.688	0.901	113	Yes	-
RBX1	9978	115	1.185	0.934	148	Yes	-
PSMB7	5695	118	0.982	0.934	90	Yes	-
HNRNPC	3183	108	1.812	0.973	181	Yes	-
TREX1	11277	51	-0.051	0.882	91	Yes	-
ATP6V1B2	526	53	0.881	1.076	278	-	-
COQ6	51004	2	-0.029	0.960	22	-	-
RPSA	3921	120	1.327	1.151	152	Yes	-
CAD	790	91	0.807	0.973	400	-	-
RPA2	6118	96	1.250	1.151	76	Yes	-
PSMB2	5690	116	0.877	0.956	169	Yes	-
ACTB	60	134	1.153	1.151	610	Yes	-
PSMD11	5717	124	1.095	1.106	218	Yes	-
RUVBL2	10856	95	0.693	0.956	532	Yes	-
RAN	5901	89	0.632	0.899	258	Yes	-
HSPD1	3329	70	0.913	1.035	325	Yes	-

Interactions (42)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMB2	5690	TREX1	11277	pd	<	reg.ITFP.txt: no annot
ACTB	60	HSPD1	3329	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastLow
CAD	790	TREX1	11277	pd	<	reg.ITFP.txt: no annot
PSMB1	5689	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
ACTB	60	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast
PSMB1	5689	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast, MINT, YeastHigh, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast; int.Mint: MI:0915(physical association)
HSPD1	3329	COQ6	51004	pp	--	int.I2D: YeastLow, IntAct_Yeast
ACTB	60	RBX1	9978	pp	--	int.I2D: BioGrid_Yeast
RPSA	3921	RAN	5901	pp	--	int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
CAD	790	COQ6	51004	pp	--	int.I2D: IntAct_Yeast
ACTB	60	CAD	790	pp	--	int.I2D: IntAct_Yeast
PSMB7	5695	RBX1	9978	pd	<	reg.ITFP.txt: no annot
CAD	790	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
CAD	790	RUVBL2	10856	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
ATP6V1B2	526	COQ6	51004	pp	--	int.I2D: IntAct_Yeast
PSMB7	5695	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
HNRNPC	3183	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
PSMB1	5689	PSMB7	5695	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastLow, IntAct, Krogan_Core, MINT_Yeast, Yu_GoldStd; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PSMB2	5690	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
ACTB	60	RAN	5901	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, NON_CORE
CAD	790	RAN	5901	pp	--	int.I2D: IntAct_Yeast
PSMB7	5695	TREX1	11277	pd	<	reg.ITFP.txt: no annot
ATP6V1B2	526	RUVBL2	10856	pp	--	int.I2D: IntAct_Yeast
ACTB	60	COQ6	51004	pp	--	int.I2D: BioGrid_Yeast
RPSA	3921	RUVBL2	10856	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB	60	PSMB7	5695	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RPA2	6118	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
CAD	790	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast
ATP6V1B2	526	RPSA	3921	pp	--	int.I2D: IntAct_Yeast
PSMD11	5717	RUVBL2	10856	pp	--	int.I2D: YeastLow
PSMB1	5689	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
HSPD1	3329	RPSA	3921	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMB1	5689	TREX1	11277	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
ACTB	60	ATP6V1B2	526	pp	--	int.I2D: BioGrid_Yeast
RAN	5901	TREX1	11277	pd	<	reg.ITFP.txt: no annot
RUVBL2	10856	TREX1	11277	pd	<>	reg.ITFP.txt: no annot
ACTB	60	RUVBL2	10856	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
CAD	790	RPSA	3921	pp	--	int.I2D: IntAct_Yeast

Related GO terms (320)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005654	nucleoplasm	9.80e-09	1.60e-04	3.220	10	83	1095
GO:0005829	cytosol	1.20e-08	1.96e-04	2.372	13	125	2562
GO:0016032	viral process	1.39e-08	2.27e-04	3.918	8	55	540
GO:0006521	regulation of cellular amino acid metabolic process	1.38e-07	2.25e-03	6.351	4	21	50
GO:0070062	extracellular vesicular exosome	1.74e-07	2.84e-03	2.282	12	98	2516
GO:0000082	G1/S transition of mitotic cell cycle	2.47e-07	4.03e-03	5.088	5	33	150
GO:0000502	proteasome complex	2.53e-07	4.13e-03	6.136	4	22	58
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.02e-07	6.56e-03	5.972	4	24	65
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	4.02e-07	6.56e-03	5.972	4	22	65
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.43e-07	8.86e-03	5.865	4	24	70
GO:0005839	proteasome core complex	6.25e-07	1.02e-02	7.409	3	11	18
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	6.44e-07	1.05e-02	5.805	4	23	73
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.80e-07	1.11e-02	5.785	4	24	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	7.98e-07	1.30e-02	5.728	4	23	77
GO:0004298	threonine-type endopeptidase activity	8.72e-07	1.42e-02	7.257	3	11	20
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	8.85e-07	1.44e-02	5.691	4	25	79
GO:0010467	gene expression	1.56e-06	2.55e-02	3.416	7	58	669
GO:0016071	mRNA metabolic process	1.76e-06	2.87e-02	4.515	5	34	223
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.78e-06	2.91e-02	5.440	4	23	94
GO:0016070	RNA metabolic process	2.91e-06	4.74e-02	4.368	5	34	247
GO:0000209	protein polyubiquitination	4.13e-06	6.74e-02	5.136	4	21	116
GO:0016020	membrane	1.02e-05	1.67e-01	2.395	9	80	1746
GO:0042981	regulation of apoptotic process	1.18e-05	1.92e-01	4.756	4	26	151
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	1.86e-05	3.04e-01	5.825	3	5	54
GO:0034641	cellular nitrogen compound metabolic process	2.20e-05	3.59e-01	4.527	4	25	177
GO:0000278	mitotic cell cycle	2.94e-05	4.80e-01	3.680	5	52	398
GO:0003697	single-stranded DNA binding	3.89e-05	6.35e-01	5.471	3	9	69
GO:0043066	negative regulation of apoptotic process	4.40e-05	7.19e-01	3.558	5	30	433
GO:0035267	NuA4 histone acetyltransferase complex	8.14e-05	1.00e+00	7.187	2	4	14
GO:0006281	DNA repair	1.04e-04	1.00e+00	3.950	4	22	264
GO:0044281	small molecule metabolic process	1.18e-04	1.00e+00	2.463	7	57	1295
GO:0006259	DNA metabolic process	1.53e-04	1.00e+00	6.747	2	3	19
GO:0006298	mismatch repair	1.69e-04	1.00e+00	6.673	2	6	20
GO:0043234	protein complex	1.71e-04	1.00e+00	3.766	4	17	300
GO:0043044	ATP-dependent chromatin remodeling	2.25e-04	1.00e+00	6.471	2	4	23
GO:0031492	nucleosomal DNA binding	3.36e-04	1.00e+00	6.187	2	4	28
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	9.80e-04	1.00e+00	9.994	1	1	1
GO:0048291	isotype switching to IgG isotypes	9.80e-04	1.00e+00	9.994	1	1	1
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	9.80e-04	1.00e+00	9.994	1	1	1
GO:0070335	aspartate binding	9.80e-04	1.00e+00	9.994	1	1	1
GO:0032558	adenyl deoxyribonucleotide binding	9.80e-04	1.00e+00	9.994	1	1	1
GO:0004151	dihydroorotase activity	9.80e-04	1.00e+00	9.994	1	1	1
GO:0004070	aspartate carbamoyltransferase activity	9.80e-04	1.00e+00	9.994	1	1	1
GO:0002368	B cell cytokine production	9.80e-04	1.00e+00	9.994	1	1	1
GO:0003684	damaged DNA binding	1.12e-03	1.00e+00	5.322	2	11	51
GO:0005634	nucleus	1.37e-03	1.00e+00	1.217	11	131	4828
GO:0042995	cell projection	1.70e-03	1.00e+00	5.017	2	6	63
GO:0006310	DNA recombination	1.92e-03	1.00e+00	4.928	2	4	67
GO:0006915	apoptotic process	1.93e-03	1.00e+00	2.837	4	34	571
GO:0006407	rRNA export from nucleus	1.96e-03	1.00e+00	8.994	1	1	2
GO:0008296	3'-5'-exodeoxyribonuclease activity	1.96e-03	1.00e+00	8.994	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.96e-03	1.00e+00	8.994	1	1	2
GO:0005055	laminin receptor activity	1.96e-03	1.00e+00	8.994	1	1	2
GO:0070409	carbamoyl phosphate biosynthetic process	1.96e-03	1.00e+00	8.994	1	1	2
GO:0005515	protein binding	2.62e-03	1.00e+00	0.998	12	172	6127
GO:0071899	negative regulation of estrogen receptor binding	2.94e-03	1.00e+00	8.409	1	1	3
GO:0006458	'de novo' protein folding	2.94e-03	1.00e+00	8.409	1	1	3
GO:0071733	transcriptional activation by promoter-enhancer looping	2.94e-03	1.00e+00	8.409	1	1	3
GO:0000056	ribosomal small subunit export from nucleus	2.94e-03	1.00e+00	8.409	1	1	3
GO:0030135	coated vesicle	2.94e-03	1.00e+00	8.409	1	1	3
GO:0044205	'de novo' UMP biosynthetic process	2.94e-03	1.00e+00	8.409	1	1	3
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	2.94e-03	1.00e+00	8.409	1	1	3
GO:0016363	nuclear matrix	3.58e-03	1.00e+00	4.471	2	11	92
GO:0042470	melanosome	3.58e-03	1.00e+00	4.471	2	10	92
GO:0051082	unfolded protein binding	3.81e-03	1.00e+00	4.425	2	6	95
GO:0005730	nucleolus	3.84e-03	1.00e+00	1.862	6	70	1684
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.92e-03	1.00e+00	7.994	1	1	4
GO:0030686	90S preribosome	3.92e-03	1.00e+00	7.994	1	1	4
GO:0019788	NEDD8 ligase activity	3.92e-03	1.00e+00	7.994	1	1	4
GO:0043141	ATP-dependent 5'-3' DNA helicase activity	3.92e-03	1.00e+00	7.994	1	1	4
GO:0006543	glutamine catabolic process	3.92e-03	1.00e+00	7.994	1	1	4
GO:0031467	Cul7-RING ubiquitin ligase complex	3.92e-03	1.00e+00	7.994	1	1	4
GO:0000055	ribosomal large subunit export from nucleus	3.92e-03	1.00e+00	7.994	1	1	4
GO:0008853	exodeoxyribonuclease III activity	3.92e-03	1.00e+00	7.994	1	1	4
GO:0051414	response to cortisol	4.89e-03	1.00e+00	7.673	1	1	5
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	4.89e-03	1.00e+00	7.673	1	2	5
GO:0032407	MutSalpha complex binding	4.89e-03	1.00e+00	7.673	1	1	5
GO:2000001	regulation of DNA damage checkpoint	4.89e-03	1.00e+00	7.673	1	1	5
GO:0031461	cullin-RING ubiquitin ligase complex	4.89e-03	1.00e+00	7.673	1	1	5
GO:0071169	establishment of protein localization to chromatin	4.89e-03	1.00e+00	7.673	1	1	5
GO:0043248	proteasome assembly	4.89e-03	1.00e+00	7.673	1	1	5
GO:0046696	lipopolysaccharide receptor complex	4.89e-03	1.00e+00	7.673	1	1	5
GO:0030891	VCB complex	4.89e-03	1.00e+00	7.673	1	2	5
GO:0000730	DNA recombinase assembly	4.89e-03	1.00e+00	7.673	1	3	5
GO:0030529	ribonucleoprotein complex	5.44e-03	1.00e+00	4.162	2	8	114
GO:0019058	viral life cycle	5.54e-03	1.00e+00	4.149	2	10	115
GO:0003688	DNA replication origin binding	5.87e-03	1.00e+00	7.409	1	1	6
GO:0031466	Cul5-RING ubiquitin ligase complex	5.87e-03	1.00e+00	7.409	1	1	6
GO:0030957	Tat protein binding	5.87e-03	1.00e+00	7.409	1	4	6
GO:0046134	pyrimidine nucleoside biosynthetic process	5.87e-03	1.00e+00	7.409	1	1	6
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	5.87e-03	1.00e+00	7.409	1	1	6
GO:0032405	MutLalpha complex binding	5.87e-03	1.00e+00	7.409	1	2	6
GO:0006325	chromatin organization	6.31e-03	1.00e+00	4.052	2	4	123
GO:0006260	DNA replication	6.51e-03	1.00e+00	4.029	2	12	125
GO:0000028	ribosomal small subunit assembly	6.84e-03	1.00e+00	7.187	1	1	7
GO:0031462	Cul2-RING ubiquitin ligase complex	6.84e-03	1.00e+00	7.187	1	2	7
GO:0033180	proton-transporting V-type ATPase, V1 domain	6.84e-03	1.00e+00	7.187	1	2	7
GO:0000790	nuclear chromatin	7.34e-03	1.00e+00	3.939	2	7	133
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	7.82e-03	1.00e+00	6.994	1	2	8
GO:0070688	MLL5-L complex	7.82e-03	1.00e+00	6.994	1	1	8
GO:0000812	Swr1 complex	7.82e-03	1.00e+00	6.994	1	3	8
GO:0045116	protein neddylation	7.82e-03	1.00e+00	6.994	1	2	8
GO:0005524	ATP binding	7.84e-03	1.00e+00	1.913	5	46	1354
GO:0016887	ATPase activity	8.55e-03	1.00e+00	3.825	2	7	144
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	8.79e-03	1.00e+00	6.825	1	1	9
GO:0014075	response to amine	8.79e-03	1.00e+00	6.825	1	1	9
GO:0006228	UTP biosynthetic process	8.79e-03	1.00e+00	6.825	1	1	9
GO:0031000	response to caffeine	8.79e-03	1.00e+00	6.825	1	2	9
GO:0006457	protein folding	9.14e-03	1.00e+00	3.775	2	8	149
GO:0043032	positive regulation of macrophage activation	9.76e-03	1.00e+00	6.673	1	1	10
GO:0051604	protein maturation	9.76e-03	1.00e+00	6.673	1	1	10
GO:0032727	positive regulation of interferon-alpha production	1.07e-02	1.00e+00	6.535	1	1	11
GO:0010569	regulation of double-strand break repair via homologous recombination	1.07e-02	1.00e+00	6.535	1	1	11
GO:0031571	mitotic G1 DNA damage checkpoint	1.07e-02	1.00e+00	6.535	1	3	11
GO:0045120	pronucleus	1.07e-02	1.00e+00	6.535	1	1	11
GO:0006744	ubiquinone biosynthetic process	1.07e-02	1.00e+00	6.535	1	1	11
GO:0035458	cellular response to interferon-beta	1.07e-02	1.00e+00	6.535	1	2	11
GO:0042802	identical protein binding	1.13e-02	1.00e+00	2.640	3	18	491
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.15e-02	1.00e+00	3.602	2	5	168
GO:0070935	3'-UTR-mediated mRNA stabilization	1.17e-02	1.00e+00	6.409	1	2	12
GO:0043968	histone H2A acetylation	1.17e-02	1.00e+00	6.409	1	3	12
GO:0005838	proteasome regulatory particle	1.17e-02	1.00e+00	6.409	1	7	12
GO:0032479	regulation of type I interferon production	1.27e-02	1.00e+00	6.294	1	2	13
GO:0005662	DNA replication factor A complex	1.27e-02	1.00e+00	6.294	1	3	13
GO:0001530	lipopolysaccharide binding	1.27e-02	1.00e+00	6.294	1	2	13
GO:0000738	DNA catabolic process, exonucleolytic	1.27e-02	1.00e+00	6.294	1	2	13
GO:0008266	poly(U) RNA binding	1.27e-02	1.00e+00	6.294	1	1	13
GO:0051131	chaperone-mediated protein complex assembly	1.27e-02	1.00e+00	6.294	1	1	13
GO:0031625	ubiquitin protein ligase binding	1.31e-02	1.00e+00	3.503	2	13	180
GO:0031011	Ino80 complex	1.36e-02	1.00e+00	6.187	1	3	14
GO:0035066	positive regulation of histone acetylation	1.46e-02	1.00e+00	6.088	1	1	15
GO:0042026	protein refolding	1.46e-02	1.00e+00	6.088	1	2	15
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1.46e-02	1.00e+00	6.088	1	3	15
GO:0046034	ATP metabolic process	1.56e-02	1.00e+00	5.994	1	1	16
GO:0050998	nitric-oxide synthase binding	1.56e-02	1.00e+00	5.994	1	1	16
GO:0008408	3'-5' exonuclease activity	1.56e-02	1.00e+00	5.994	1	2	16
GO:0010243	response to organonitrogen compound	1.65e-02	1.00e+00	5.907	1	2	17
GO:0075733	intracellular transport of virus	1.65e-02	1.00e+00	5.907	1	2	17
GO:0050870	positive regulation of T cell activation	1.65e-02	1.00e+00	5.907	1	1	17
GO:0022624	proteasome accessory complex	1.65e-02	1.00e+00	5.907	1	9	17
GO:0071392	cellular response to estradiol stimulus	1.75e-02	1.00e+00	5.825	1	1	18
GO:0006541	glutamine metabolic process	1.75e-02	1.00e+00	5.825	1	1	18
GO:0035861	site of double-strand break	1.75e-02	1.00e+00	5.825	1	1	18
GO:0044822	poly(A) RNA binding	1.82e-02	1.00e+00	1.920	4	50	1078
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	1.85e-02	1.00e+00	5.747	1	1	19
GO:0048863	stem cell differentiation	1.85e-02	1.00e+00	5.747	1	1	19
GO:0032733	positive regulation of interleukin-10 production	1.85e-02	1.00e+00	5.747	1	1	19
GO:0003678	DNA helicase activity	1.85e-02	1.00e+00	5.747	1	3	19
GO:0015078	hydrogen ion transmembrane transporter activity	1.94e-02	1.00e+00	5.673	1	3	20
GO:0005719	nuclear euchromatin	1.94e-02	1.00e+00	5.673	1	2	20
GO:0000718	nucleotide-excision repair, DNA damage removal	2.04e-02	1.00e+00	5.602	1	5	21
GO:0071364	cellular response to epidermal growth factor stimulus	2.04e-02	1.00e+00	5.602	1	1	21
GO:0006297	nucleotide-excision repair, DNA gap filling	2.14e-02	1.00e+00	5.535	1	5	22
GO:0033574	response to testosterone	2.14e-02	1.00e+00	5.535	1	2	22
GO:0032201	telomere maintenance via semi-conservative replication	2.14e-02	1.00e+00	5.535	1	7	22
GO:0030863	cortical cytoskeleton	2.14e-02	1.00e+00	5.535	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	2.14e-02	1.00e+00	5.535	1	4	22
GO:0007052	mitotic spindle organization	2.14e-02	1.00e+00	5.535	1	2	22
GO:0031463	Cul3-RING ubiquitin ligase complex	2.23e-02	1.00e+00	5.471	1	2	23
GO:0043236	laminin binding	2.23e-02	1.00e+00	5.471	1	1	23
GO:0006513	protein monoubiquitination	2.23e-02	1.00e+00	5.471	1	1	23
GO:0006206	pyrimidine nucleobase metabolic process	2.33e-02	1.00e+00	5.409	1	2	24
GO:0006611	protein export from nucleus	2.42e-02	1.00e+00	5.351	1	4	25
GO:0042100	B cell proliferation	2.42e-02	1.00e+00	5.351	1	1	25
GO:0042113	B cell activation	2.42e-02	1.00e+00	5.351	1	2	25
GO:0017144	drug metabolic process	2.42e-02	1.00e+00	5.351	1	1	25
GO:0032735	positive regulation of interleukin-12 production	2.42e-02	1.00e+00	5.351	1	1	25
GO:0000722	telomere maintenance via recombination	2.52e-02	1.00e+00	5.294	1	7	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	2.52e-02	1.00e+00	5.294	1	2	26
GO:0004003	ATP-dependent DNA helicase activity	2.62e-02	1.00e+00	5.240	1	3	27
GO:0071339	MLL1 complex	2.62e-02	1.00e+00	5.240	1	3	27
GO:0015991	ATP hydrolysis coupled proton transport	2.71e-02	1.00e+00	5.187	1	4	28
GO:0043022	ribosome binding	2.71e-02	1.00e+00	5.187	1	3	28
GO:0043967	histone H4 acetylation	2.71e-02	1.00e+00	5.187	1	3	28
GO:0019894	kinesin binding	2.71e-02	1.00e+00	5.187	1	1	28
GO:0019005	SCF ubiquitin ligase complex	2.81e-02	1.00e+00	5.136	1	1	29
GO:0003730	mRNA 3'-UTR binding	2.81e-02	1.00e+00	5.136	1	2	29
GO:0006271	DNA strand elongation involved in DNA replication	3.00e-02	1.00e+00	5.040	1	9	31
GO:0015992	proton transport	3.09e-02	1.00e+00	4.994	1	3	32
GO:0034644	cellular response to UV	3.09e-02	1.00e+00	4.994	1	5	32
GO:0033572	transferrin transport	3.09e-02	1.00e+00	4.994	1	6	32
GO:0019899	enzyme binding	3.16e-02	1.00e+00	2.825	2	11	288
GO:0051701	interaction with host	3.28e-02	1.00e+00	4.907	1	4	34
GO:0034332	adherens junction organization	3.47e-02	1.00e+00	4.825	1	1	36
GO:0006200	ATP catabolic process	3.47e-02	1.00e+00	2.751	2	14	303
GO:0001895	retina homeostasis	3.47e-02	1.00e+00	4.825	1	1	36
GO:0032755	positive regulation of interleukin-6 production	3.47e-02	1.00e+00	4.825	1	2	36
GO:0051084	'de novo' posttranslational protein folding	3.57e-02	1.00e+00	4.785	1	4	37
GO:0018107	peptidyl-threonine phosphorylation	3.57e-02	1.00e+00	4.785	1	1	37
GO:0070527	platelet aggregation	3.66e-02	1.00e+00	4.747	1	2	38
GO:0050681	androgen receptor binding	3.66e-02	1.00e+00	4.747	1	4	38
GO:0090382	phagosome maturation	3.66e-02	1.00e+00	4.747	1	5	38
GO:0031490	chromatin DNA binding	3.76e-02	1.00e+00	4.709	1	2	39
GO:0006284	base-excision repair	3.76e-02	1.00e+00	4.709	1	7	39
GO:0032729	positive regulation of interferon-gamma production	3.76e-02	1.00e+00	4.709	1	2	39
GO:0022627	cytosolic small ribosomal subunit	3.76e-02	1.00e+00	4.709	1	3	39
GO:0032092	positive regulation of protein binding	3.76e-02	1.00e+00	4.709	1	3	39
GO:0007595	lactation	3.76e-02	1.00e+00	4.709	1	2	39
GO:0000781	chromosome, telomeric region	3.85e-02	1.00e+00	4.673	1	2	40
GO:0043195	terminal bouton	3.95e-02	1.00e+00	4.637	1	1	41
GO:0030521	androgen receptor signaling pathway	3.95e-02	1.00e+00	4.637	1	2	41
GO:0005902	microvillus	4.04e-02	1.00e+00	4.602	1	2	42
GO:0032508	DNA duplex unwinding	4.04e-02	1.00e+00	4.602	1	4	42
GO:0042110	T cell activation	4.14e-02	1.00e+00	4.568	1	3	43
GO:0014070	response to organic cyclic compound	4.14e-02	1.00e+00	4.568	1	3	43
GO:0007286	spermatid development	4.23e-02	1.00e+00	4.535	1	1	44
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	4.23e-02	1.00e+00	4.535	1	2	44
GO:0021762	substantia nigra development	4.42e-02	1.00e+00	4.471	1	1	46
GO:0006283	transcription-coupled nucleotide-excision repair	4.42e-02	1.00e+00	4.471	1	8	46
GO:0019003	GDP binding	4.61e-02	1.00e+00	4.409	1	2	48
GO:0031100	organ regeneration	4.79e-02	1.00e+00	4.351	1	4	50
GO:0035690	cellular response to drug	4.79e-02	1.00e+00	4.351	1	2	50
GO:0006986	response to unfolded protein	4.89e-02	1.00e+00	4.322	1	2	51
GO:0005905	coated pit	4.89e-02	1.00e+00	4.322	1	2	51
GO:0040008	regulation of growth	4.89e-02	1.00e+00	4.322	1	3	51
GO:0003725	double-stranded RNA binding	5.17e-02	1.00e+00	4.240	1	6	54
GO:0090305	nucleic acid phosphodiester bond hydrolysis	5.17e-02	1.00e+00	4.240	1	2	54
GO:0002039	p53 binding	5.26e-02	1.00e+00	4.213	1	7	55
GO:0050660	flavin adenine dinucleotide binding	5.45e-02	1.00e+00	4.162	1	2	57
GO:0006879	cellular iron ion homeostasis	5.45e-02	1.00e+00	4.162	1	5	57
GO:0000724	double-strand break repair via homologous recombination	5.45e-02	1.00e+00	4.162	1	6	57
GO:0012505	endomembrane system	5.45e-02	1.00e+00	4.162	1	2	57
GO:0051087	chaperone binding	5.63e-02	1.00e+00	4.112	1	6	59
GO:0045216	cell-cell junction organization	5.63e-02	1.00e+00	4.112	1	2	59
GO:0000723	telomere maintenance	5.63e-02	1.00e+00	4.112	1	8	59
GO:0005643	nuclear pore	5.63e-02	1.00e+00	4.112	1	4	59
GO:0032481	positive regulation of type I interferon production	5.82e-02	1.00e+00	4.064	1	6	61
GO:0006302	double-strand break repair	5.91e-02	1.00e+00	4.040	1	8	62
GO:0019903	protein phosphatase binding	6.00e-02	1.00e+00	4.017	1	4	63
GO:0030141	secretory granule	6.37e-02	1.00e+00	3.928	1	2	67
GO:0006338	chromatin remodeling	6.46e-02	1.00e+00	3.907	1	4	68
GO:0006289	nucleotide-excision repair	6.56e-02	1.00e+00	3.886	1	12	69
GO:0034329	cell junction assembly	6.74e-02	1.00e+00	3.845	1	1	71
GO:0000785	chromatin	6.92e-02	1.00e+00	3.805	1	5	73
GO:0055086	nucleobase-containing small molecule metabolic process	6.92e-02	1.00e+00	3.805	1	5	73
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	7.20e-02	1.00e+00	3.747	1	3	76
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	7.29e-02	1.00e+00	3.728	1	5	77
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	7.29e-02	1.00e+00	3.728	1	6	77
GO:0071013	catalytic step 2 spliceosome	7.47e-02	1.00e+00	3.691	1	7	79
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	7.56e-02	1.00e+00	3.673	1	2	80
GO:0007565	female pregnancy	7.56e-02	1.00e+00	3.673	1	2	80
GO:0019083	viral transcription	7.66e-02	1.00e+00	3.655	1	8	81
GO:0001889	liver development	7.75e-02	1.00e+00	3.637	1	3	82
GO:0001726	ruffle	7.75e-02	1.00e+00	3.637	1	4	82
GO:0005681	spliceosomal complex	7.84e-02	1.00e+00	3.619	1	3	83
GO:0047485	protein N-terminus binding	8.11e-02	1.00e+00	3.568	1	4	86
GO:0006415	translational termination	8.20e-02	1.00e+00	3.551	1	8	87
GO:0044267	cellular protein metabolic process	8.33e-02	1.00e+00	2.043	2	24	495
GO:0050821	protein stabilization	8.56e-02	1.00e+00	3.487	1	2	91
GO:0003690	double-stranded DNA binding	8.56e-02	1.00e+00	3.487	1	4	91
GO:0016605	PML body	8.65e-02	1.00e+00	3.471	1	5	92
GO:0006928	cellular component movement	8.65e-02	1.00e+00	3.471	1	7	92
GO:0006414	translational elongation	8.74e-02	1.00e+00	3.455	1	11	93
GO:0005200	structural constituent of cytoskeleton	8.74e-02	1.00e+00	3.455	1	7	93
GO:0001649	osteoblast differentiation	8.92e-02	1.00e+00	3.425	1	6	95
GO:0071456	cellular response to hypoxia	9.19e-02	1.00e+00	3.380	1	4	98
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	9.73e-02	1.00e+00	3.294	1	8	104
GO:0014069	postsynaptic density	9.90e-02	1.00e+00	3.267	1	1	106
GO:0015630	microtubule cytoskeleton	1.04e-01	1.00e+00	3.187	1	5	112
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.06e-01	1.00e+00	3.162	1	10	114
GO:0005635	nuclear envelope	1.08e-01	1.00e+00	3.136	1	6	116
GO:0072562	blood microparticle	1.08e-01	1.00e+00	3.136	1	4	116
GO:0007219	Notch signaling pathway	1.16e-01	1.00e+00	3.029	1	4	125
GO:0006511	ubiquitin-dependent protein catabolic process	1.18e-01	1.00e+00	3.006	1	5	127
GO:0006413	translational initiation	1.21e-01	1.00e+00	2.961	1	12	131
GO:0045087	innate immune response	1.21e-01	1.00e+00	1.728	2	20	616
GO:0003735	structural constituent of ribosome	1.30e-01	1.00e+00	2.855	1	8	141
GO:0007507	heart development	1.30e-01	1.00e+00	2.855	1	5	141
GO:0008286	insulin receptor signaling pathway	1.32e-01	1.00e+00	2.825	1	6	144
GO:0061024	membrane organization	1.34e-01	1.00e+00	2.805	1	5	146
GO:0005769	early endosome	1.44e-01	1.00e+00	2.691	1	2	158
GO:0046777	protein autophosphorylation	1.44e-01	1.00e+00	2.691	1	3	158
GO:0000398	mRNA splicing, via spliceosome	1.50e-01	1.00e+00	2.628	1	12	165
GO:0030424	axon	1.56e-01	1.00e+00	2.568	1	3	172
GO:0004672	protein kinase activity	1.61e-01	1.00e+00	2.519	1	2	178
GO:0019904	protein domain specific binding	1.63e-01	1.00e+00	2.495	1	6	181
GO:0032403	protein complex binding	1.67e-01	1.00e+00	2.463	1	7	185
GO:0003924	GTPase activity	1.82e-01	1.00e+00	2.329	1	9	203
GO:0005765	lysosomal membrane	1.94e-01	1.00e+00	2.226	1	5	218
GO:0006184	GTP catabolic process	1.95e-01	1.00e+00	2.213	1	9	220
GO:0005622	intracellular	2.00e-01	1.00e+00	2.174	1	5	226
GO:0007067	mitotic nuclear division	2.04e-01	1.00e+00	2.143	1	13	231
GO:0008380	RNA splicing	2.05e-01	1.00e+00	2.136	1	13	232
GO:0005759	mitochondrial matrix	2.06e-01	1.00e+00	2.130	1	12	233
GO:0006412	translation	2.07e-01	1.00e+00	2.118	1	15	235
GO:0003713	transcription coactivator activity	2.10e-01	1.00e+00	2.094	1	10	239
GO:0043025	neuronal cell body	2.22e-01	1.00e+00	2.006	1	4	254
GO:0004842	ubiquitin-protein transferase activity	2.24e-01	1.00e+00	1.994	1	4	256
GO:0000166	nucleotide binding	2.36e-01	1.00e+00	1.907	1	6	272
GO:0043065	positive regulation of apoptotic process	2.37e-01	1.00e+00	1.896	1	8	274
GO:0007264	small GTPase mediated signal transduction	2.49e-01	1.00e+00	1.815	1	3	290
GO:0016567	protein ubiquitination	2.56e-01	1.00e+00	1.770	1	5	299
GO:0005743	mitochondrial inner membrane	2.57e-01	1.00e+00	1.766	1	5	300
GO:0005615	extracellular space	2.60e-01	1.00e+00	1.014	2	17	1010
GO:0005856	cytoskeleton	2.65e-01	1.00e+00	1.714	1	8	311
GO:0019901	protein kinase binding	2.72e-01	1.00e+00	1.673	1	21	320
GO:0005739	mitochondrion	2.74e-01	1.00e+00	0.964	2	24	1046
GO:0007411	axon guidance	2.77e-01	1.00e+00	1.641	1	9	327
GO:0005525	GTP binding	2.77e-01	1.00e+00	1.637	1	11	328
GO:0043231	intracellular membrane-bounded organelle	2.80e-01	1.00e+00	1.619	1	8	332
GO:0008270	zinc ion binding	2.82e-01	1.00e+00	0.935	2	12	1067
GO:0003682	chromatin binding	2.82e-01	1.00e+00	1.611	1	12	334
GO:0003723	RNA binding	2.97e-01	1.00e+00	1.523	1	19	355
GO:0005925	focal adhesion	3.07e-01	1.00e+00	1.463	1	18	370
GO:0007155	cell adhesion	3.17e-01	1.00e+00	1.409	1	8	384
GO:0009986	cell surface	3.43e-01	1.00e+00	1.273	1	9	422
GO:0005737	cytoplasm	3.47e-01	1.00e+00	0.359	5	98	3976
GO:0007596	blood coagulation	3.70e-01	1.00e+00	1.136	1	14	464
GO:0055114	oxidation-reduction process	3.81e-01	1.00e+00	1.085	1	11	481
GO:0045893	positive regulation of transcription, DNA-templated	3.84e-01	1.00e+00	1.067	1	17	487
GO:0055085	transmembrane transport	4.01e-01	1.00e+00	0.989	1	8	514
GO:0042803	protein homodimerization activity	4.60e-01	1.00e+00	0.725	1	11	617
GO:0005789	endoplasmic reticulum membrane	4.71e-01	1.00e+00	0.682	1	10	636
GO:0005794	Golgi apparatus	4.78e-01	1.00e+00	0.650	1	14	650
GO:0005886	plasma membrane	5.43e-01	1.00e+00	0.111	3	38	2834
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	5.58e-01	1.00e+00	0.331	1	19	811
GO:0007165	signal transduction	6.17e-01	1.00e+00	0.103	1	17	950
GO:0046872	metal ion binding	7.78e-01	1.00e+00	-0.522	1	24	1465
GO:0006351	transcription, DNA-templated	8.05e-01	1.00e+00	-0.636	1	25	1585
GO:0016021	integral component of membrane	9.29e-01	1.00e+00	-1.283	1	15	2483

Wolf-ratios-Mammosphere-Adherent

meta-int-snw-51004

Interacting subnets

Genes (16)

Interactions (42)

Related GO terms (320)