Subnetwork | Dataset | Score | p-value 1 | p-value 2 | p-value 3 | Size | Highlighted genes |
---|---|---|---|---|---|---|---|
reg-snw-56655 | wolf-screen-ratio-mammosphere-adherent | 0.828 | 9.29e-07 | 2.91e-03 | 5.53e-03 | 8 | 7 |
int-snw-2771 | wolf-screen-ratio-mammosphere-adherent | 1.057 | 1.36e-20 | 1.28e-04 | 4.17e-03 | 8 | 8 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
RPA2 | 6118 | 96 | 1.250 | 1.151 | 76 | Yes | - |
PSMD1 | 5707 | 86 | 0.836 | 0.830 | 118 | Yes | - |
PSMA2 | 5683 | 112 | 1.093 | 1.106 | 108 | Yes | - |
RBX1 | 9978 | 115 | 1.185 | 0.934 | 148 | Yes | - |
PSMB7 | 5695 | 118 | 0.982 | 0.934 | 90 | Yes | - |
PSMB2 | 5690 | 116 | 0.877 | 0.956 | 169 | Yes | - |
PSMD11 | 5717 | 124 | 1.095 | 1.106 | 218 | Yes | - |
VARS | 7407 | 86 | 0.549 | 1.002 | 204 | Yes | - |
ACTB | 60 | 134 | 1.153 | 1.151 | 610 | Yes | - |
GNAI2 | 2771 | 10 | -0.516 | 1.057 | 98 | - | Yes |
POLE4 | 56655 | 63 | 0.177 | 0.828 | 56 | - | - |
PSMB3 | 5691 | 64 | 0.668 | 0.901 | 19 | Yes | - |
RPSA | 3921 | 120 | 1.327 | 1.151 | 152 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
PSMA2 | 5683 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast |
PSMB2 | 5690 | POLE4 | 56655 | pd | < | reg.ITFP.txt: no annot |
PSMA2 | 5683 | PSMD1 | 5707 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA2 | 5683 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | PSMB2 | 5690 | pp | -- | int.I2D: BioGrid_Yeast |
RPSA | 3921 | VARS | 7407 | pp | -- | int.I2D: IntAct_Yeast |
PSMD1 | 5707 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast |
ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
PSMB7 | 5695 | RBX1 | 9978 | pd | < | reg.ITFP.txt: no annot |
VARS | 7407 | POLE4 | 56655 | pd | <> | reg.ITFP.txt: no annot |
PSMA2 | 5683 | PSMB3 | 5691 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd |
PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA2 | 5683 | POLE4 | 56655 | pd | < | reg.ITFP.txt: no annot |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB7 | 5695 | POLE4 | 56655 | pd | < | reg.ITFP.txt: no annot |
PSMB2 | 5690 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct |
ACTB | 60 | GNAI2 | 2771 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
PSMB3 | 5691 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS; int.HPRD: yeast 2-hybrid |
PSMB7 | 5695 | PSMD1 | 5707 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct |
ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB2 | 5690 | PSMB3 | 5691 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid |
ACTB | 60 | RPA2 | 6118 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
PSMB3 | 5691 | POLE4 | 56655 | pd | < | reg.ITFP.txt: no annot |
GNAI2 | 2771 | PSMD1 | 5707 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB2 | 5690 | PSMD11 | 5717 | pd | < | reg.ITFP.txt: no annot |
PSMB2 | 5690 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMB2 | 5690 | VARS | 7407 | pd | < | reg.ITFP.txt: no annot |
PSMB3 | 5691 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
PSMB2 | 5690 | PSMD1 | 5707 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA2 | 5683 | PSMB2 | 5690 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0006521 | regulation of cellular amino acid metabolic process | 1.02e-12 | 1.67e-08 | 7.235 | 6 | 21 | 50 |
GO:0000502 | proteasome complex | 2.60e-12 | 4.24e-08 | 7.021 | 6 | 22 | 58 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 5.29e-12 | 8.63e-08 | 6.857 | 6 | 24 | 65 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 5.29e-12 | 8.63e-08 | 6.857 | 6 | 22 | 65 |
GO:0000082 | G1/S transition of mitotic cell cycle | 7.88e-12 | 1.29e-07 | 5.873 | 7 | 33 | 150 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 8.38e-12 | 1.37e-07 | 6.750 | 6 | 24 | 70 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 1.09e-11 | 1.77e-07 | 6.689 | 6 | 23 | 73 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.18e-11 | 1.93e-07 | 6.670 | 6 | 24 | 74 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 1.51e-11 | 2.47e-07 | 6.612 | 6 | 23 | 77 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.77e-11 | 2.89e-07 | 6.575 | 6 | 25 | 79 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 5.16e-11 | 8.42e-07 | 6.324 | 6 | 23 | 94 |
GO:0016071 | mRNA metabolic process | 1.30e-10 | 2.11e-06 | 5.300 | 7 | 34 | 223 |
GO:0000209 | protein polyubiquitination | 1.86e-10 | 3.04e-06 | 6.021 | 6 | 21 | 116 |
GO:0016070 | RNA metabolic process | 2.65e-10 | 4.33e-06 | 5.153 | 7 | 34 | 247 |
GO:0005839 | proteasome core complex | 7.36e-10 | 1.20e-05 | 8.124 | 4 | 11 | 18 |
GO:0042981 | regulation of apoptotic process | 9.23e-10 | 1.51e-05 | 5.641 | 6 | 26 | 151 |
GO:0004298 | threonine-type endopeptidase activity | 1.16e-09 | 1.90e-05 | 7.972 | 4 | 11 | 20 |
GO:0016032 | viral process | 1.52e-09 | 2.48e-05 | 4.217 | 8 | 55 | 540 |
GO:0034641 | cellular nitrogen compound metabolic process | 2.41e-09 | 3.93e-05 | 5.411 | 6 | 25 | 177 |
GO:0000278 | mitotic cell cycle | 7.36e-09 | 1.20e-04 | 4.465 | 7 | 52 | 398 |
GO:0010467 | gene expression | 8.20e-09 | 1.34e-04 | 3.908 | 8 | 58 | 669 |
GO:0005654 | nucleoplasm | 1.49e-08 | 2.43e-04 | 3.367 | 9 | 83 | 1095 |
GO:0005829 | cytosol | 8.02e-08 | 1.31e-03 | 2.430 | 11 | 125 | 2562 |
GO:0043066 | negative regulation of apoptotic process | 4.94e-07 | 8.06e-03 | 4.121 | 6 | 30 | 433 |
GO:0006915 | apoptotic process | 2.49e-06 | 4.06e-02 | 3.722 | 6 | 34 | 571 |
GO:0070062 | extracellular vesicular exosome | 1.92e-05 | 3.13e-01 | 2.167 | 9 | 98 | 2516 |
GO:0005838 | proteasome regulatory particle | 3.85e-05 | 6.28e-01 | 7.709 | 2 | 7 | 12 |
GO:0022624 | proteasome accessory complex | 7.91e-05 | 1.00e+00 | 7.207 | 2 | 9 | 17 |
GO:0044281 | small molecule metabolic process | 2.60e-04 | 1.00e+00 | 2.540 | 6 | 57 | 1295 |
GO:0005515 | protein binding | 6.98e-04 | 1.00e+00 | 1.172 | 11 | 172 | 6127 |
GO:0016020 | membrane | 1.31e-03 | 1.00e+00 | 2.109 | 6 | 80 | 1746 |
GO:0004832 | valine-tRNA ligase activity | 1.59e-03 | 1.00e+00 | 9.294 | 1 | 1 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 1.59e-03 | 1.00e+00 | 9.294 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 1.59e-03 | 1.00e+00 | 9.294 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 1.59e-03 | 1.00e+00 | 9.294 | 1 | 1 | 2 |
GO:0006438 | valyl-tRNA aminoacylation | 1.59e-03 | 1.00e+00 | 9.294 | 1 | 1 | 2 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 3.18e-03 | 1.00e+00 | 8.294 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 3.18e-03 | 1.00e+00 | 8.294 | 1 | 1 | 4 |
GO:0031467 | Cul7-RING ubiquitin ligase complex | 3.18e-03 | 1.00e+00 | 8.294 | 1 | 1 | 4 |
GO:0019788 | NEDD8 ligase activity | 3.18e-03 | 1.00e+00 | 8.294 | 1 | 1 | 4 |
GO:0050805 | negative regulation of synaptic transmission | 3.18e-03 | 1.00e+00 | 8.294 | 1 | 1 | 4 |
GO:0005634 | nucleus | 3.61e-03 | 1.00e+00 | 1.227 | 9 | 131 | 4828 |
GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 3.98e-03 | 1.00e+00 | 7.972 | 1 | 2 | 5 |
GO:0031461 | cullin-RING ubiquitin ligase complex | 3.98e-03 | 1.00e+00 | 7.972 | 1 | 1 | 5 |
GO:0043248 | proteasome assembly | 3.98e-03 | 1.00e+00 | 7.972 | 1 | 1 | 5 |
GO:0030891 | VCB complex | 3.98e-03 | 1.00e+00 | 7.972 | 1 | 2 | 5 |
GO:0000730 | DNA recombinase assembly | 3.98e-03 | 1.00e+00 | 7.972 | 1 | 3 | 5 |
GO:2000001 | regulation of DNA damage checkpoint | 3.98e-03 | 1.00e+00 | 7.972 | 1 | 1 | 5 |
GO:0008622 | epsilon DNA polymerase complex | 3.98e-03 | 1.00e+00 | 7.972 | 1 | 1 | 5 |
GO:0030957 | Tat protein binding | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 4 | 6 |
GO:0031466 | Cul5-RING ubiquitin ligase complex | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 6 |
GO:0000028 | ribosomal small subunit assembly | 5.56e-03 | 1.00e+00 | 7.487 | 1 | 1 | 7 |
GO:0002161 | aminoacyl-tRNA editing activity | 5.56e-03 | 1.00e+00 | 7.487 | 1 | 2 | 7 |
GO:0031462 | Cul2-RING ubiquitin ligase complex | 5.56e-03 | 1.00e+00 | 7.487 | 1 | 2 | 7 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 6.36e-03 | 1.00e+00 | 7.294 | 1 | 5 | 8 |
GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 6.36e-03 | 1.00e+00 | 7.294 | 1 | 2 | 8 |
GO:0070688 | MLL5-L complex | 6.36e-03 | 1.00e+00 | 7.294 | 1 | 1 | 8 |
GO:0045116 | protein neddylation | 6.36e-03 | 1.00e+00 | 7.294 | 1 | 2 | 8 |
GO:0001973 | adenosine receptor signaling pathway | 7.15e-03 | 1.00e+00 | 7.124 | 1 | 1 | 9 |
GO:0006450 | regulation of translational fidelity | 7.94e-03 | 1.00e+00 | 6.972 | 1 | 2 | 10 |
GO:0031625 | ubiquitin protein ligase binding | 8.71e-03 | 1.00e+00 | 3.802 | 2 | 13 | 180 |
GO:0010569 | regulation of double-strand break repair via homologous recombination | 8.73e-03 | 1.00e+00 | 6.835 | 1 | 1 | 11 |
GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway | 8.73e-03 | 1.00e+00 | 6.835 | 1 | 1 | 11 |
GO:0031571 | mitotic G1 DNA damage checkpoint | 8.73e-03 | 1.00e+00 | 6.835 | 1 | 3 | 11 |
GO:0005662 | DNA replication factor A complex | 1.03e-02 | 1.00e+00 | 6.594 | 1 | 3 | 13 |
GO:0030234 | enzyme regulator activity | 1.03e-02 | 1.00e+00 | 6.594 | 1 | 3 | 13 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.11e-02 | 1.00e+00 | 6.487 | 1 | 4 | 14 |
GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex | 1.19e-02 | 1.00e+00 | 6.387 | 1 | 1 | 15 |
GO:0050998 | nitric-oxide synthase binding | 1.27e-02 | 1.00e+00 | 6.294 | 1 | 1 | 16 |
GO:0042176 | regulation of protein catabolic process | 1.27e-02 | 1.00e+00 | 6.294 | 1 | 3 | 16 |
GO:0010243 | response to organonitrogen compound | 1.35e-02 | 1.00e+00 | 6.207 | 1 | 2 | 17 |
GO:0035861 | site of double-strand break | 1.42e-02 | 1.00e+00 | 6.124 | 1 | 1 | 18 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.50e-02 | 1.00e+00 | 6.046 | 1 | 1 | 19 |
GO:0048863 | stem cell differentiation | 1.50e-02 | 1.00e+00 | 6.046 | 1 | 1 | 19 |
GO:0006298 | mismatch repair | 1.58e-02 | 1.00e+00 | 5.972 | 1 | 6 | 20 |
GO:0007214 | gamma-aminobutyric acid signaling pathway | 1.58e-02 | 1.00e+00 | 5.972 | 1 | 1 | 20 |
GO:0007194 | negative regulation of adenylate cyclase activity | 1.66e-02 | 1.00e+00 | 5.902 | 1 | 1 | 21 |
GO:0031683 | G-protein beta/gamma-subunit complex binding | 1.66e-02 | 1.00e+00 | 5.902 | 1 | 1 | 21 |
GO:0000718 | nucleotide-excision repair, DNA damage removal | 1.66e-02 | 1.00e+00 | 5.902 | 1 | 5 | 21 |
GO:0006297 | nucleotide-excision repair, DNA gap filling | 1.74e-02 | 1.00e+00 | 5.835 | 1 | 5 | 22 |
GO:0051924 | regulation of calcium ion transport | 1.74e-02 | 1.00e+00 | 5.835 | 1 | 1 | 22 |
GO:0032201 | telomere maintenance via semi-conservative replication | 1.74e-02 | 1.00e+00 | 5.835 | 1 | 7 | 22 |
GO:0030863 | cortical cytoskeleton | 1.74e-02 | 1.00e+00 | 5.835 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 1.74e-02 | 1.00e+00 | 5.835 | 1 | 4 | 22 |
GO:0006281 | DNA repair | 1.81e-02 | 1.00e+00 | 3.250 | 2 | 22 | 264 |
GO:0043044 | ATP-dependent chromatin remodeling | 1.82e-02 | 1.00e+00 | 5.770 | 1 | 4 | 23 |
GO:0031463 | Cul3-RING ubiquitin ligase complex | 1.82e-02 | 1.00e+00 | 5.770 | 1 | 2 | 23 |
GO:0043236 | laminin binding | 1.82e-02 | 1.00e+00 | 5.770 | 1 | 1 | 23 |
GO:0006513 | protein monoubiquitination | 1.82e-02 | 1.00e+00 | 5.770 | 1 | 1 | 23 |
GO:0000722 | telomere maintenance via recombination | 2.05e-02 | 1.00e+00 | 5.594 | 1 | 7 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 2.05e-02 | 1.00e+00 | 5.594 | 1 | 2 | 26 |
GO:0043022 | ribosome binding | 2.21e-02 | 1.00e+00 | 5.487 | 1 | 3 | 28 |
GO:0031492 | nucleosomal DNA binding | 2.21e-02 | 1.00e+00 | 5.487 | 1 | 4 | 28 |
GO:0019894 | kinesin binding | 2.21e-02 | 1.00e+00 | 5.487 | 1 | 1 | 28 |
GO:0019005 | SCF ubiquitin ligase complex | 2.29e-02 | 1.00e+00 | 5.436 | 1 | 1 | 29 |
GO:0003887 | DNA-directed DNA polymerase activity | 2.29e-02 | 1.00e+00 | 5.436 | 1 | 3 | 29 |
GO:0071897 | DNA biosynthetic process | 2.29e-02 | 1.00e+00 | 5.436 | 1 | 2 | 29 |
GO:0006271 | DNA strand elongation involved in DNA replication | 2.44e-02 | 1.00e+00 | 5.340 | 1 | 9 | 31 |
GO:0005834 | heterotrimeric G-protein complex | 2.68e-02 | 1.00e+00 | 5.207 | 1 | 1 | 34 |
GO:0034332 | adherens junction organization | 2.83e-02 | 1.00e+00 | 5.124 | 1 | 1 | 36 |
GO:0001895 | retina homeostasis | 2.83e-02 | 1.00e+00 | 5.124 | 1 | 1 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 2.91e-02 | 1.00e+00 | 5.085 | 1 | 4 | 37 |
GO:0070527 | platelet aggregation | 2.99e-02 | 1.00e+00 | 5.046 | 1 | 2 | 38 |
GO:0001664 | G-protein coupled receptor binding | 2.99e-02 | 1.00e+00 | 5.046 | 1 | 1 | 38 |
GO:0022627 | cytosolic small ribosomal subunit | 3.06e-02 | 1.00e+00 | 5.009 | 1 | 3 | 39 |
GO:0006284 | base-excision repair | 3.06e-02 | 1.00e+00 | 5.009 | 1 | 7 | 39 |
GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | 3.14e-02 | 1.00e+00 | 4.972 | 1 | 1 | 40 |
GO:0000781 | chromosome, telomeric region | 3.14e-02 | 1.00e+00 | 4.972 | 1 | 2 | 40 |
GO:0006418 | tRNA aminoacylation for protein translation | 3.30e-02 | 1.00e+00 | 4.902 | 1 | 5 | 42 |
GO:0014070 | response to organic cyclic compound | 3.37e-02 | 1.00e+00 | 4.868 | 1 | 3 | 43 |
GO:0043966 | histone H3 acetylation | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 2 | 45 |
GO:0021762 | substantia nigra development | 3.60e-02 | 1.00e+00 | 4.770 | 1 | 1 | 46 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 3.60e-02 | 1.00e+00 | 4.770 | 1 | 8 | 46 |
GO:0005730 | nucleolus | 3.77e-02 | 1.00e+00 | 1.576 | 4 | 70 | 1684 |
GO:0003684 | damaged DNA binding | 3.99e-02 | 1.00e+00 | 4.622 | 1 | 11 | 51 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 4.22e-02 | 1.00e+00 | 4.539 | 1 | 5 | 54 |
GO:0000186 | activation of MAPKK activity | 4.22e-02 | 1.00e+00 | 4.539 | 1 | 1 | 54 |
GO:0000932 | cytoplasmic mRNA processing body | 4.37e-02 | 1.00e+00 | 4.487 | 1 | 3 | 56 |
GO:0000724 | double-strand break repair via homologous recombination | 4.45e-02 | 1.00e+00 | 4.461 | 1 | 6 | 57 |
GO:0000723 | telomere maintenance | 4.60e-02 | 1.00e+00 | 4.411 | 1 | 8 | 59 |
GO:0045216 | cell-cell junction organization | 4.60e-02 | 1.00e+00 | 4.411 | 1 | 2 | 59 |
GO:0006302 | double-strand break repair | 4.83e-02 | 1.00e+00 | 4.340 | 1 | 8 | 62 |
GO:0019903 | protein phosphatase binding | 4.91e-02 | 1.00e+00 | 4.317 | 1 | 4 | 63 |
GO:0007596 | blood coagulation | 5.11e-02 | 1.00e+00 | 2.436 | 2 | 14 | 464 |
GO:0006289 | nucleotide-excision repair | 5.36e-02 | 1.00e+00 | 4.185 | 1 | 12 | 69 |
GO:0003697 | single-stranded DNA binding | 5.36e-02 | 1.00e+00 | 4.185 | 1 | 9 | 69 |
GO:0034329 | cell junction assembly | 5.51e-02 | 1.00e+00 | 4.144 | 1 | 1 | 71 |
GO:0007584 | response to nutrient | 5.59e-02 | 1.00e+00 | 4.124 | 1 | 3 | 72 |
GO:0044267 | cellular protein metabolic process | 5.74e-02 | 1.00e+00 | 2.343 | 2 | 24 | 495 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 5.89e-02 | 1.00e+00 | 4.046 | 1 | 3 | 76 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 5.96e-02 | 1.00e+00 | 4.027 | 1 | 5 | 77 |
GO:0051301 | cell division | 6.27e-02 | 1.00e+00 | 3.954 | 1 | 6 | 81 |
GO:0019083 | viral transcription | 6.27e-02 | 1.00e+00 | 3.954 | 1 | 8 | 81 |
GO:0047485 | protein N-terminus binding | 6.64e-02 | 1.00e+00 | 3.868 | 1 | 4 | 86 |
GO:0006415 | translational termination | 6.71e-02 | 1.00e+00 | 3.851 | 1 | 8 | 87 |
GO:0016605 | PML body | 7.09e-02 | 1.00e+00 | 3.770 | 1 | 5 | 92 |
GO:0006928 | cellular component movement | 7.09e-02 | 1.00e+00 | 3.770 | 1 | 7 | 92 |
GO:0006414 | translational elongation | 7.16e-02 | 1.00e+00 | 3.755 | 1 | 11 | 93 |
GO:0005200 | structural constituent of cytoskeleton | 7.16e-02 | 1.00e+00 | 3.755 | 1 | 7 | 93 |
GO:0071456 | cellular response to hypoxia | 7.53e-02 | 1.00e+00 | 3.679 | 1 | 4 | 98 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 7.98e-02 | 1.00e+00 | 3.594 | 1 | 8 | 104 |
GO:0014069 | postsynaptic density | 8.12e-02 | 1.00e+00 | 3.566 | 1 | 1 | 106 |
GO:0030496 | midbody | 8.35e-02 | 1.00e+00 | 3.526 | 1 | 4 | 109 |
GO:0015630 | microtubule cytoskeleton | 8.57e-02 | 1.00e+00 | 3.487 | 1 | 5 | 112 |
GO:0030529 | ribonucleoprotein complex | 8.71e-02 | 1.00e+00 | 3.461 | 1 | 8 | 114 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 8.71e-02 | 1.00e+00 | 3.461 | 1 | 10 | 114 |
GO:0019058 | viral life cycle | 8.79e-02 | 1.00e+00 | 3.449 | 1 | 10 | 115 |
GO:0072562 | blood microparticle | 8.86e-02 | 1.00e+00 | 3.436 | 1 | 4 | 116 |
GO:0006325 | chromatin organization | 9.37e-02 | 1.00e+00 | 3.351 | 1 | 4 | 123 |
GO:0007219 | Notch signaling pathway | 9.51e-02 | 1.00e+00 | 3.328 | 1 | 4 | 125 |
GO:0006260 | DNA replication | 9.51e-02 | 1.00e+00 | 3.328 | 1 | 12 | 125 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 9.66e-02 | 1.00e+00 | 3.305 | 1 | 5 | 127 |
GO:0006413 | translational initiation | 9.95e-02 | 1.00e+00 | 3.261 | 1 | 12 | 131 |
GO:0009615 | response to virus | 1.00e-01 | 1.00e+00 | 3.250 | 1 | 6 | 132 |
GO:0000790 | nuclear chromatin | 1.01e-01 | 1.00e+00 | 3.239 | 1 | 7 | 133 |
GO:0031982 | vesicle | 1.02e-01 | 1.00e+00 | 3.228 | 1 | 10 | 134 |
GO:0003735 | structural constituent of ribosome | 1.07e-01 | 1.00e+00 | 3.154 | 1 | 8 | 141 |
GO:0061024 | membrane organization | 1.10e-01 | 1.00e+00 | 3.104 | 1 | 5 | 146 |
GO:0006457 | protein folding | 1.12e-01 | 1.00e+00 | 3.075 | 1 | 8 | 149 |
GO:0045121 | membrane raft | 1.21e-01 | 1.00e+00 | 2.963 | 1 | 8 | 161 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.26e-01 | 1.00e+00 | 2.902 | 1 | 5 | 168 |
GO:0030424 | axon | 1.29e-01 | 1.00e+00 | 2.868 | 1 | 3 | 172 |
GO:0007049 | cell cycle | 1.32e-01 | 1.00e+00 | 2.826 | 1 | 3 | 177 |
GO:0015629 | actin cytoskeleton | 1.36e-01 | 1.00e+00 | 2.778 | 1 | 5 | 183 |
GO:0032403 | protein complex binding | 1.38e-01 | 1.00e+00 | 2.763 | 1 | 7 | 185 |
GO:0003924 | GTPase activity | 1.50e-01 | 1.00e+00 | 2.629 | 1 | 9 | 203 |
GO:0030168 | platelet activation | 1.52e-01 | 1.00e+00 | 2.615 | 1 | 9 | 205 |
GO:0004871 | signal transducer activity | 1.59e-01 | 1.00e+00 | 2.539 | 1 | 4 | 216 |
GO:0006184 | GTP catabolic process | 1.62e-01 | 1.00e+00 | 2.513 | 1 | 9 | 220 |
GO:0006412 | translation | 1.72e-01 | 1.00e+00 | 2.417 | 1 | 15 | 235 |
GO:0004842 | ubiquitin-protein transferase activity | 1.86e-01 | 1.00e+00 | 2.294 | 1 | 4 | 256 |
GO:0005739 | mitochondrion | 2.01e-01 | 1.00e+00 | 1.263 | 2 | 24 | 1046 |
GO:0019899 | enzyme binding | 2.07e-01 | 1.00e+00 | 2.124 | 1 | 11 | 288 |
GO:0043234 | protein complex | 2.14e-01 | 1.00e+00 | 2.065 | 1 | 17 | 300 |
GO:0016567 | protein ubiquitination | 2.14e-01 | 1.00e+00 | 2.070 | 1 | 5 | 299 |
GO:0005856 | cytoskeleton | 2.21e-01 | 1.00e+00 | 2.013 | 1 | 8 | 311 |
GO:0035556 | intracellular signal transduction | 2.25e-01 | 1.00e+00 | 1.986 | 1 | 6 | 317 |
GO:0019901 | protein kinase binding | 2.27e-01 | 1.00e+00 | 1.972 | 1 | 21 | 320 |
GO:0007411 | axon guidance | 2.31e-01 | 1.00e+00 | 1.941 | 1 | 9 | 327 |
GO:0005525 | GTP binding | 2.32e-01 | 1.00e+00 | 1.936 | 1 | 11 | 328 |
GO:0008283 | cell proliferation | 2.34e-01 | 1.00e+00 | 1.923 | 1 | 12 | 331 |
GO:0005813 | centrosome | 2.39e-01 | 1.00e+00 | 1.889 | 1 | 12 | 339 |
GO:0007268 | synaptic transmission | 2.48e-01 | 1.00e+00 | 1.830 | 1 | 2 | 353 |
GO:0043565 | sequence-specific DNA binding | 2.55e-01 | 1.00e+00 | 1.782 | 1 | 4 | 365 |
GO:0007186 | G-protein coupled receptor signaling pathway | 2.56e-01 | 1.00e+00 | 1.774 | 1 | 5 | 367 |
GO:0005925 | focal adhesion | 2.58e-01 | 1.00e+00 | 1.763 | 1 | 18 | 370 |
GO:0007155 | cell adhesion | 2.66e-01 | 1.00e+00 | 1.709 | 1 | 8 | 384 |
GO:0008284 | positive regulation of cell proliferation | 2.71e-01 | 1.00e+00 | 1.679 | 1 | 8 | 392 |
GO:0046982 | protein heterodimerization activity | 2.75e-01 | 1.00e+00 | 1.654 | 1 | 11 | 399 |
GO:0005524 | ATP binding | 2.94e-01 | 1.00e+00 | 0.891 | 2 | 46 | 1354 |
GO:0005737 | cytoplasm | 3.94e-01 | 1.00e+00 | 0.337 | 4 | 98 | 3976 |
GO:0045087 | innate immune response | 3.94e-01 | 1.00e+00 | 1.027 | 1 | 20 | 616 |
GO:0005794 | Golgi apparatus | 4.11e-01 | 1.00e+00 | 0.950 | 1 | 14 | 650 |
GO:0007165 | signal transduction | 5.42e-01 | 1.00e+00 | 0.402 | 1 | 17 | 950 |
GO:0005615 | extracellular space | 5.64e-01 | 1.00e+00 | 0.314 | 1 | 17 | 1010 |
GO:0008270 | zinc ion binding | 5.85e-01 | 1.00e+00 | 0.235 | 1 | 12 | 1067 |
GO:0044822 | poly(A) RNA binding | 5.89e-01 | 1.00e+00 | 0.220 | 1 | 50 | 1078 |
GO:0005886 | plasma membrane | 6.87e-01 | 1.00e+00 | -0.175 | 2 | 38 | 2834 |
GO:0046872 | metal ion binding | 7.06e-01 | 1.00e+00 | -0.223 | 1 | 24 | 1465 |