Subnetwork | Dataset | Score | p-value 1 | p-value 2 | p-value 3 | Size | Highlighted genes |
---|---|---|---|---|---|---|---|
reg-snw-56655 | wolf-screen-ratio-mammosphere-adherent | 0.828 | 9.29e-07 | 2.91e-03 | 5.53e-03 | 8 | 7 |
int-snw-27343 | wolf-screen-ratio-mammosphere-adherent | 0.950 | 4.14e-16 | 1.77e-03 | 3.14e-02 | 12 | 12 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
PSMA2 | 5683 | 112 | 1.093 | 1.106 | 108 | Yes | - |
RBX1 | 9978 | 115 | 1.185 | 0.934 | 148 | Yes | - |
PSMB7 | 5695 | 118 | 0.982 | 0.934 | 90 | Yes | - |
PSMD7 | 5713 | 15 | 0.640 | 0.958 | 133 | Yes | - |
PSMA1 | 5682 | 100 | 0.996 | 0.878 | 152 | Yes | - |
VARS | 7407 | 86 | 0.549 | 1.002 | 204 | Yes | - |
POLE4 | 56655 | 63 | 0.177 | 0.828 | 56 | - | - |
RPSA | 3921 | 120 | 1.327 | 1.151 | 152 | Yes | - |
PSMB3 | 5691 | 64 | 0.668 | 0.901 | 19 | Yes | - |
PGD | 5226 | 89 | 1.201 | 1.106 | 152 | Yes | - |
ACO2 | 50 | 65 | 1.000 | 1.076 | 191 | Yes | - |
PSMD13 | 5719 | 56 | 0.848 | 0.801 | 114 | Yes | - |
POLL | 27343 | 2 | 0.025 | 0.950 | 31 | Yes | - |
PSMB2 | 5690 | 116 | 0.877 | 0.956 | 169 | Yes | - |
ACTB | 60 | 134 | 1.153 | 1.151 | 610 | Yes | - |
PSMD11 | 5717 | 124 | 1.095 | 1.106 | 218 | Yes | - |
PSMC1 | 5700 | 51 | 0.840 | 1.018 | 137 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
PSMA1 | 5682 | PSMD13 | 5719 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastMedium, BioGrid, BioGrid_Yeast, IntAct_Yeast |
PSMA1 | 5682 | PSMB2 | 5690 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
PSMA2 | 5683 | PSMD13 | 5719 | pp | -- | int.I2D: YeastLow |
PSMB7 | 5695 | PSMD7 | 5713 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | PSMD7 | 5713 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA2 | 5683 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast |
PSMD7 | 5713 | PSMD13 | 5719 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, MINT_Yeast, YeastHigh, IntAct_Fly, Krogan_Core, Tarassov_PCA |
ACTB | 60 | PSMD13 | 5719 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB2 | 5690 | POLE4 | 56655 | pd | < | reg.ITFP.txt: no annot |
PSMB7 | 5695 | PSMC1 | 5700 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA2 | 5683 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
ACO2 | 50 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
PSMB2 | 5690 | PSMD13 | 5719 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
ACTB | 60 | PSMB2 | 5690 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA1 | 5682 | PSMB3 | 5691 | pp | -- | int.Intact: MI:0914(association); int.I2D: IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Yeast, YeastHigh, BioGrid_Yeast |
PSMC1 | 5700 | PSMD13 | 5719 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, MINT_Yeast, YeastHigh, BioGrid, IntAct_Yeast, Krogan_Core |
RPSA | 3921 | VARS | 7407 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | PSMC1 | 5700 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB2 | 5690 | PSMD7 | 5713 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
PSMA1 | 5682 | PSMA2 | 5683 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
PSMD13 | 5719 | POLL | 27343 | pp | -- | int.I2D: BioGrid_Yeast, Krogan_NonCore |
PSMD11 | 5717 | POLL | 27343 | pp | -- | int.I2D: Krogan_NonCore |
PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast |
ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB7 | 5695 | RBX1 | 9978 | pd | < | reg.ITFP.txt: no annot |
PSMC1 | 5700 | POLL | 27343 | pp | -- | int.I2D: BioGrid_Yeast |
PGD | 5226 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
VARS | 7407 | POLE4 | 56655 | pd | <> | reg.ITFP.txt: no annot |
PSMA2 | 5683 | PSMB3 | 5691 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd |
PSMA1 | 5682 | PSMD7 | 5713 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium, IntAct_Yeast, MINT_Yeast |
PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA2 | 5683 | POLE4 | 56655 | pd | < | reg.ITFP.txt: no annot |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
ACO2 | 50 | PSMC1 | 5700 | pp | -- | int.I2D: YeastLow |
PSMB3 | 5691 | PSMC1 | 5700 | pp | -- | int.I2D: YeastLow |
PSMB7 | 5695 | POLE4 | 56655 | pd | < | reg.ITFP.txt: no annot |
PSMB2 | 5690 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct |
PSMD7 | 5713 | RBX1 | 9978 | pp | -- | int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast |
PSMB3 | 5691 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS; int.HPRD: yeast 2-hybrid |
ACO2 | 50 | PSMD7 | 5713 | pp | -- | int.I2D: YeastLow |
PSMC1 | 5700 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB2 | 5690 | PSMB3 | 5691 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid |
PSMA2 | 5683 | PSMC1 | 5700 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Fly, YeastLow |
ACO2 | 50 | PGD | 5226 | pp | -- | int.I2D: YeastLow |
PSMC1 | 5700 | PSMD7 | 5713 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid, IntAct, MINT_Yeast, YeastHigh, BCI, BioGrid_Yeast, HPRD, Krogan_Core; int.HPRD: in vitro |
PSMB7 | 5695 | PSMD13 | 5719 | pd | < | reg.ITFP.txt: no annot |
PSMB3 | 5691 | POLE4 | 56655 | pd | < | reg.ITFP.txt: no annot |
PSMA2 | 5683 | PSMD7 | 5713 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMB2 | 5690 | PSMD11 | 5717 | pd | < | reg.ITFP.txt: no annot |
PSMB2 | 5690 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMB2 | 5690 | VARS | 7407 | pd | < | reg.ITFP.txt: no annot |
PSMD7 | 5713 | POLL | 27343 | pp | -- | int.I2D: Krogan_NonCore |
PSMA1 | 5682 | PSMC1 | 5700 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct_Fly, YeastMedium, IntAct |
PSMD11 | 5717 | PSMD13 | 5719 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastHigh, BioGrid, INTEROLOG |
PSMB3 | 5691 | PSMD13 | 5719 | pp | -- | int.I2D: YeastLow |
PSMD7 | 5713 | PSMD11 | 5717 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastHigh, BioGrid, IntAct |
PSMB3 | 5691 | PSMD7 | 5713 | pp | -- | int.I2D: YeastLow |
PSMB3 | 5691 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
PSMB2 | 5690 | PSMC1 | 5700 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
PSMA2 | 5683 | PSMB2 | 5690 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0006521 | regulation of cellular amino acid metabolic process | 2.65e-19 | 4.32e-15 | 7.433 | 9 | 21 | 50 |
GO:0000502 | proteasome complex | 1.12e-18 | 1.83e-14 | 7.219 | 9 | 22 | 58 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 3.36e-18 | 5.48e-14 | 7.055 | 9 | 24 | 65 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 3.36e-18 | 5.48e-14 | 7.055 | 9 | 22 | 65 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 6.81e-18 | 1.11e-13 | 6.948 | 9 | 24 | 70 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 1.02e-17 | 1.66e-13 | 6.887 | 9 | 23 | 73 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.16e-17 | 1.89e-13 | 6.867 | 9 | 24 | 74 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 1.68e-17 | 2.75e-13 | 6.810 | 9 | 23 | 77 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 2.15e-17 | 3.50e-13 | 6.773 | 9 | 25 | 79 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 1.10e-16 | 1.80e-12 | 6.522 | 9 | 23 | 94 |
GO:0000209 | protein polyubiquitination | 7.82e-16 | 1.28e-11 | 6.219 | 9 | 21 | 116 |
GO:0016071 | mRNA metabolic process | 3.31e-15 | 5.41e-11 | 5.428 | 10 | 34 | 223 |
GO:0000082 | G1/S transition of mitotic cell cycle | 8.38e-15 | 1.37e-10 | 5.848 | 9 | 33 | 150 |
GO:0042981 | regulation of apoptotic process | 8.91e-15 | 1.45e-10 | 5.838 | 9 | 26 | 151 |
GO:0016070 | RNA metabolic process | 9.31e-15 | 1.52e-10 | 5.281 | 10 | 34 | 247 |
GO:0034641 | cellular nitrogen compound metabolic process | 3.82e-14 | 6.23e-10 | 5.609 | 9 | 25 | 177 |
GO:0016032 | viral process | 4.86e-13 | 7.94e-09 | 4.290 | 11 | 55 | 540 |
GO:0010467 | gene expression | 5.01e-12 | 8.17e-08 | 3.981 | 11 | 58 | 669 |
GO:0005839 | proteasome core complex | 5.45e-12 | 8.90e-08 | 8.059 | 5 | 11 | 18 |
GO:0004298 | threonine-type endopeptidase activity | 9.86e-12 | 1.61e-07 | 7.907 | 5 | 11 | 20 |
GO:0000278 | mitotic cell cycle | 5.70e-11 | 9.31e-07 | 4.440 | 9 | 52 | 398 |
GO:0043066 | negative regulation of apoptotic process | 1.21e-10 | 1.97e-06 | 4.319 | 9 | 30 | 433 |
GO:0005838 | proteasome regulatory particle | 3.97e-10 | 6.47e-06 | 8.322 | 4 | 7 | 12 |
GO:0005654 | nucleoplasm | 1.00e-09 | 1.64e-05 | 3.270 | 11 | 83 | 1095 |
GO:0006915 | apoptotic process | 1.40e-09 | 2.28e-05 | 3.920 | 9 | 34 | 571 |
GO:0005829 | cytosol | 2.27e-09 | 3.70e-05 | 2.391 | 14 | 125 | 2562 |
GO:0044281 | small molecule metabolic process | 5.96e-09 | 9.73e-05 | 3.028 | 11 | 57 | 1295 |
GO:0022624 | proteasome accessory complex | 6.33e-07 | 1.03e-02 | 7.404 | 3 | 9 | 17 |
GO:0070062 | extracellular vesicular exosome | 5.73e-06 | 9.35e-02 | 2.069 | 11 | 98 | 2516 |
GO:0005634 | nucleus | 1.00e-05 | 1.64e-01 | 1.477 | 14 | 131 | 4828 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 2.85e-05 | 4.65e-01 | 7.907 | 2 | 5 | 8 |
GO:0003887 | DNA-directed DNA polymerase activity | 4.08e-04 | 1.00e+00 | 6.049 | 2 | 3 | 29 |
GO:0071897 | DNA biosynthetic process | 4.08e-04 | 1.00e+00 | 6.049 | 2 | 2 | 29 |
GO:0019521 | D-gluconate metabolic process | 1.04e-03 | 1.00e+00 | 9.907 | 1 | 1 | 1 |
GO:0016020 | membrane | 1.17e-03 | 1.00e+00 | 1.944 | 7 | 80 | 1746 |
GO:0004832 | valine-tRNA ligase activity | 2.08e-03 | 1.00e+00 | 8.907 | 1 | 1 | 2 |
GO:0051538 | 3 iron, 4 sulfur cluster binding | 2.08e-03 | 1.00e+00 | 8.907 | 1 | 1 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 2.08e-03 | 1.00e+00 | 8.907 | 1 | 1 | 2 |
GO:0019322 | pentose biosynthetic process | 2.08e-03 | 1.00e+00 | 8.907 | 1 | 1 | 2 |
GO:0003994 | aconitate hydratase activity | 2.08e-03 | 1.00e+00 | 8.907 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 2.08e-03 | 1.00e+00 | 8.907 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 2.08e-03 | 1.00e+00 | 8.907 | 1 | 1 | 2 |
GO:0006438 | valyl-tRNA aminoacylation | 2.08e-03 | 1.00e+00 | 8.907 | 1 | 1 | 2 |
GO:0007127 | meiosis I | 2.08e-03 | 1.00e+00 | 8.907 | 1 | 1 | 2 |
GO:0009051 | pentose-phosphate shunt, oxidative branch | 3.12e-03 | 1.00e+00 | 8.322 | 1 | 1 | 3 |
GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity | 3.12e-03 | 1.00e+00 | 8.322 | 1 | 1 | 3 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 4.16e-03 | 1.00e+00 | 7.907 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 4.16e-03 | 1.00e+00 | 7.907 | 1 | 1 | 4 |
GO:0031467 | Cul7-RING ubiquitin ligase complex | 4.16e-03 | 1.00e+00 | 7.907 | 1 | 1 | 4 |
GO:0019788 | NEDD8 ligase activity | 4.16e-03 | 1.00e+00 | 7.907 | 1 | 1 | 4 |
GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 5.20e-03 | 1.00e+00 | 7.585 | 1 | 2 | 5 |
GO:0031461 | cullin-RING ubiquitin ligase complex | 5.20e-03 | 1.00e+00 | 7.585 | 1 | 1 | 5 |
GO:0043248 | proteasome assembly | 5.20e-03 | 1.00e+00 | 7.585 | 1 | 1 | 5 |
GO:0006102 | isocitrate metabolic process | 5.20e-03 | 1.00e+00 | 7.585 | 1 | 1 | 5 |
GO:0030891 | VCB complex | 5.20e-03 | 1.00e+00 | 7.585 | 1 | 2 | 5 |
GO:0008622 | epsilon DNA polymerase complex | 5.20e-03 | 1.00e+00 | 7.585 | 1 | 1 | 5 |
GO:0005515 | protein binding | 5.86e-03 | 1.00e+00 | 0.911 | 12 | 172 | 6127 |
GO:0030957 | Tat protein binding | 6.23e-03 | 1.00e+00 | 7.322 | 1 | 4 | 6 |
GO:0006101 | citrate metabolic process | 6.23e-03 | 1.00e+00 | 7.322 | 1 | 1 | 6 |
GO:0031466 | Cul5-RING ubiquitin ligase complex | 6.23e-03 | 1.00e+00 | 7.322 | 1 | 1 | 6 |
GO:0000028 | ribosomal small subunit assembly | 7.27e-03 | 1.00e+00 | 7.100 | 1 | 1 | 7 |
GO:0002161 | aminoacyl-tRNA editing activity | 7.27e-03 | 1.00e+00 | 7.100 | 1 | 2 | 7 |
GO:0031462 | Cul2-RING ubiquitin ligase complex | 7.27e-03 | 1.00e+00 | 7.100 | 1 | 2 | 7 |
GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 8.30e-03 | 1.00e+00 | 6.907 | 1 | 2 | 8 |
GO:0070688 | MLL5-L complex | 8.30e-03 | 1.00e+00 | 6.907 | 1 | 1 | 8 |
GO:0045116 | protein neddylation | 8.30e-03 | 1.00e+00 | 6.907 | 1 | 2 | 8 |
GO:0016446 | somatic hypermutation of immunoglobulin genes | 9.34e-03 | 1.00e+00 | 6.737 | 1 | 1 | 9 |
GO:0006450 | regulation of translational fidelity | 1.04e-02 | 1.00e+00 | 6.585 | 1 | 2 | 10 |
GO:0006098 | pentose-phosphate shunt | 1.14e-02 | 1.00e+00 | 6.448 | 1 | 3 | 11 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.45e-02 | 1.00e+00 | 6.100 | 1 | 4 | 14 |
GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex | 1.55e-02 | 1.00e+00 | 6.000 | 1 | 1 | 15 |
GO:0016829 | lyase activity | 1.55e-02 | 1.00e+00 | 6.000 | 1 | 1 | 15 |
GO:0050998 | nitric-oxide synthase binding | 1.65e-02 | 1.00e+00 | 5.907 | 1 | 1 | 16 |
GO:0010243 | response to organonitrogen compound | 1.76e-02 | 1.00e+00 | 5.820 | 1 | 2 | 17 |
GO:0017025 | TBP-class protein binding | 1.86e-02 | 1.00e+00 | 5.737 | 1 | 2 | 18 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.96e-02 | 1.00e+00 | 5.659 | 1 | 1 | 19 |
GO:0048863 | stem cell differentiation | 1.96e-02 | 1.00e+00 | 5.659 | 1 | 1 | 19 |
GO:0030863 | cortical cytoskeleton | 2.27e-02 | 1.00e+00 | 5.448 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 2.27e-02 | 1.00e+00 | 5.448 | 1 | 4 | 22 |
GO:0043044 | ATP-dependent chromatin remodeling | 2.37e-02 | 1.00e+00 | 5.383 | 1 | 4 | 23 |
GO:0031463 | Cul3-RING ubiquitin ligase complex | 2.37e-02 | 1.00e+00 | 5.383 | 1 | 2 | 23 |
GO:0043236 | laminin binding | 2.37e-02 | 1.00e+00 | 5.383 | 1 | 1 | 23 |
GO:0006513 | protein monoubiquitination | 2.37e-02 | 1.00e+00 | 5.383 | 1 | 1 | 23 |
GO:0005730 | nucleolus | 2.50e-02 | 1.00e+00 | 1.511 | 5 | 70 | 1684 |
GO:0005844 | polysome | 2.57e-02 | 1.00e+00 | 5.263 | 1 | 4 | 25 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 2.68e-02 | 1.00e+00 | 5.207 | 1 | 2 | 26 |
GO:0043022 | ribosome binding | 2.88e-02 | 1.00e+00 | 5.100 | 1 | 3 | 28 |
GO:0031492 | nucleosomal DNA binding | 2.88e-02 | 1.00e+00 | 5.100 | 1 | 4 | 28 |
GO:0019894 | kinesin binding | 2.88e-02 | 1.00e+00 | 5.100 | 1 | 1 | 28 |
GO:0006099 | tricarboxylic acid cycle | 2.98e-02 | 1.00e+00 | 5.049 | 1 | 3 | 29 |
GO:0019005 | SCF ubiquitin ligase complex | 2.98e-02 | 1.00e+00 | 5.049 | 1 | 1 | 29 |
GO:0050661 | NADP binding | 3.28e-02 | 1.00e+00 | 4.907 | 1 | 1 | 32 |
GO:0034332 | adherens junction organization | 3.69e-02 | 1.00e+00 | 4.737 | 1 | 1 | 36 |
GO:0001895 | retina homeostasis | 3.69e-02 | 1.00e+00 | 4.737 | 1 | 1 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 3.79e-02 | 1.00e+00 | 4.698 | 1 | 4 | 37 |
GO:0051539 | 4 iron, 4 sulfur cluster binding | 3.79e-02 | 1.00e+00 | 4.698 | 1 | 3 | 37 |
GO:0070527 | platelet aggregation | 3.89e-02 | 1.00e+00 | 4.659 | 1 | 2 | 38 |
GO:0022627 | cytosolic small ribosomal subunit | 3.99e-02 | 1.00e+00 | 4.622 | 1 | 3 | 39 |
GO:0006418 | tRNA aminoacylation for protein translation | 4.29e-02 | 1.00e+00 | 4.515 | 1 | 5 | 42 |
GO:0014070 | response to organic cyclic compound | 4.39e-02 | 1.00e+00 | 4.481 | 1 | 3 | 43 |
GO:0043966 | histone H3 acetylation | 4.59e-02 | 1.00e+00 | 4.415 | 1 | 2 | 45 |
GO:0021762 | substantia nigra development | 4.69e-02 | 1.00e+00 | 4.383 | 1 | 1 | 46 |
GO:0006091 | generation of precursor metabolites and energy | 5.18e-02 | 1.00e+00 | 4.235 | 1 | 3 | 51 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 5.48e-02 | 1.00e+00 | 4.152 | 1 | 5 | 54 |
GO:0000932 | cytoplasmic mRNA processing body | 5.68e-02 | 1.00e+00 | 4.100 | 1 | 3 | 56 |
GO:0045216 | cell-cell junction organization | 5.97e-02 | 1.00e+00 | 4.024 | 1 | 2 | 59 |
GO:0006289 | nucleotide-excision repair | 6.95e-02 | 1.00e+00 | 3.798 | 1 | 12 | 69 |
GO:0034329 | cell junction assembly | 7.15e-02 | 1.00e+00 | 3.757 | 1 | 1 | 71 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 7.63e-02 | 1.00e+00 | 3.659 | 1 | 3 | 76 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 7.73e-02 | 1.00e+00 | 3.640 | 1 | 5 | 77 |
GO:0019083 | viral transcription | 8.11e-02 | 1.00e+00 | 3.567 | 1 | 8 | 81 |
GO:0006415 | translational termination | 8.69e-02 | 1.00e+00 | 3.464 | 1 | 8 | 87 |
GO:0005739 | mitochondrion | 9.12e-02 | 1.00e+00 | 1.461 | 3 | 24 | 1046 |
GO:0006928 | cellular component movement | 9.17e-02 | 1.00e+00 | 3.383 | 1 | 7 | 92 |
GO:0044267 | cellular protein metabolic process | 9.25e-02 | 1.00e+00 | 1.956 | 2 | 24 | 495 |
GO:0006414 | translational elongation | 9.26e-02 | 1.00e+00 | 3.368 | 1 | 11 | 93 |
GO:0005200 | structural constituent of cytoskeleton | 9.26e-02 | 1.00e+00 | 3.368 | 1 | 7 | 93 |
GO:0071456 | cellular response to hypoxia | 9.74e-02 | 1.00e+00 | 3.292 | 1 | 4 | 98 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 1.03e-01 | 1.00e+00 | 3.207 | 1 | 8 | 104 |
GO:0014069 | postsynaptic density | 1.05e-01 | 1.00e+00 | 3.179 | 1 | 1 | 106 |
GO:0015630 | microtubule cytoskeleton | 1.11e-01 | 1.00e+00 | 3.100 | 1 | 5 | 112 |
GO:0030529 | ribonucleoprotein complex | 1.12e-01 | 1.00e+00 | 3.074 | 1 | 8 | 114 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 1.12e-01 | 1.00e+00 | 3.074 | 1 | 10 | 114 |
GO:0019058 | viral life cycle | 1.13e-01 | 1.00e+00 | 3.061 | 1 | 10 | 115 |
GO:0072562 | blood microparticle | 1.14e-01 | 1.00e+00 | 3.049 | 1 | 4 | 116 |
GO:0044237 | cellular metabolic process | 1.16e-01 | 1.00e+00 | 3.024 | 1 | 3 | 118 |
GO:0006325 | chromatin organization | 1.21e-01 | 1.00e+00 | 2.964 | 1 | 4 | 123 |
GO:0007219 | Notch signaling pathway | 1.23e-01 | 1.00e+00 | 2.941 | 1 | 4 | 125 |
GO:0006260 | DNA replication | 1.23e-01 | 1.00e+00 | 2.941 | 1 | 12 | 125 |
GO:0005506 | iron ion binding | 1.24e-01 | 1.00e+00 | 2.918 | 1 | 3 | 127 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 1.24e-01 | 1.00e+00 | 2.918 | 1 | 5 | 127 |
GO:0006413 | translational initiation | 1.28e-01 | 1.00e+00 | 2.874 | 1 | 12 | 131 |
GO:0009615 | response to virus | 1.29e-01 | 1.00e+00 | 2.863 | 1 | 6 | 132 |
GO:0000790 | nuclear chromatin | 1.30e-01 | 1.00e+00 | 2.852 | 1 | 7 | 133 |
GO:0003735 | structural constituent of ribosome | 1.37e-01 | 1.00e+00 | 2.767 | 1 | 8 | 141 |
GO:0016887 | ATPase activity | 1.40e-01 | 1.00e+00 | 2.737 | 1 | 7 | 144 |
GO:0061024 | membrane organization | 1.42e-01 | 1.00e+00 | 2.717 | 1 | 5 | 146 |
GO:0006457 | protein folding | 1.44e-01 | 1.00e+00 | 2.688 | 1 | 8 | 149 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.61e-01 | 1.00e+00 | 2.515 | 1 | 5 | 168 |
GO:0005524 | ATP binding | 1.62e-01 | 1.00e+00 | 1.089 | 3 | 46 | 1354 |
GO:0030424 | axon | 1.65e-01 | 1.00e+00 | 2.481 | 1 | 3 | 172 |
GO:0031625 | ubiquitin protein ligase binding | 1.72e-01 | 1.00e+00 | 2.415 | 1 | 13 | 180 |
GO:0015629 | actin cytoskeleton | 1.75e-01 | 1.00e+00 | 2.391 | 1 | 5 | 183 |
GO:0032403 | protein complex binding | 1.76e-01 | 1.00e+00 | 2.376 | 1 | 7 | 185 |
GO:0005759 | mitochondrial matrix | 2.17e-01 | 1.00e+00 | 2.043 | 1 | 12 | 233 |
GO:0006412 | translation | 2.19e-01 | 1.00e+00 | 2.030 | 1 | 15 | 235 |
GO:0004842 | ubiquitin-protein transferase activity | 2.36e-01 | 1.00e+00 | 1.907 | 1 | 4 | 256 |
GO:0006281 | DNA repair | 2.42e-01 | 1.00e+00 | 1.863 | 1 | 22 | 264 |
GO:0005975 | carbohydrate metabolic process | 2.50e-01 | 1.00e+00 | 1.809 | 1 | 5 | 274 |
GO:0016567 | protein ubiquitination | 2.70e-01 | 1.00e+00 | 1.683 | 1 | 5 | 299 |
GO:0043234 | protein complex | 2.71e-01 | 1.00e+00 | 1.678 | 1 | 17 | 300 |
GO:0006200 | ATP catabolic process | 2.73e-01 | 1.00e+00 | 1.664 | 1 | 14 | 303 |
GO:0005856 | cytoskeleton | 2.79e-01 | 1.00e+00 | 1.626 | 1 | 8 | 311 |
GO:0019901 | protein kinase binding | 2.86e-01 | 1.00e+00 | 1.585 | 1 | 21 | 320 |
GO:0007411 | axon guidance | 2.91e-01 | 1.00e+00 | 1.554 | 1 | 9 | 327 |
GO:0005813 | centrosome | 3.00e-01 | 1.00e+00 | 1.502 | 1 | 12 | 339 |
GO:0044822 | poly(A) RNA binding | 3.11e-01 | 1.00e+00 | 0.833 | 2 | 50 | 1078 |
GO:0003723 | RNA binding | 3.12e-01 | 1.00e+00 | 1.435 | 1 | 19 | 355 |
GO:0043565 | sequence-specific DNA binding | 3.19e-01 | 1.00e+00 | 1.395 | 1 | 4 | 365 |
GO:0005925 | focal adhesion | 3.23e-01 | 1.00e+00 | 1.376 | 1 | 18 | 370 |
GO:0007155 | cell adhesion | 3.33e-01 | 1.00e+00 | 1.322 | 1 | 8 | 384 |
GO:0046982 | protein heterodimerization activity | 3.44e-01 | 1.00e+00 | 1.267 | 1 | 11 | 399 |
GO:0007596 | blood coagulation | 3.88e-01 | 1.00e+00 | 1.049 | 1 | 14 | 464 |
GO:0055114 | oxidation-reduction process | 3.99e-01 | 1.00e+00 | 0.997 | 1 | 11 | 481 |
GO:0045087 | innate immune response | 4.80e-01 | 1.00e+00 | 0.640 | 1 | 20 | 616 |
GO:0042803 | protein homodimerization activity | 4.81e-01 | 1.00e+00 | 0.638 | 1 | 11 | 617 |
GO:0005794 | Golgi apparatus | 4.99e-01 | 1.00e+00 | 0.563 | 1 | 14 | 650 |
GO:0005737 | cytoplasm | 6.24e-01 | 1.00e+00 | -0.050 | 4 | 98 | 3976 |
GO:0005615 | extracellular space | 6.63e-01 | 1.00e+00 | -0.073 | 1 | 17 | 1010 |
GO:0008270 | zinc ion binding | 6.83e-01 | 1.00e+00 | -0.152 | 1 | 12 | 1067 |
GO:0003677 | DNA binding | 7.70e-01 | 1.00e+00 | -0.493 | 1 | 26 | 1351 |
GO:0046872 | metal ion binding | 7.98e-01 | 1.00e+00 | -0.610 | 1 | 24 | 1465 |
GO:0005886 | plasma membrane | 9.61e-01 | 1.00e+00 | -1.562 | 1 | 38 | 2834 |