meta-int-snw-1857

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-56655 wolf-screen-ratio-mammosphere-adherent 0.828 9.29e-07 2.91e-03 5.53e-03 8 7
int-snw-1857 wolf-screen-ratio-mammosphere-adherent 0.946 6.29e-16 1.96e-03 3.38e-02 14 13
wolf-screen-ratio-mammosphere-adherent-meta-int-snw-1857 subnetwork

Genes (19)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
PSMA2 5683 1121.0931.106108Yes-
RBX1 9978 1151.1850.934148Yes-
PSMB7 5695 1180.9820.93490Yes-
PSMA1 5682 1000.9960.878152Yes-
EIF4A1 1973 60.8660.98171Yes-
VARS 7407 860.5491.002204Yes-
DVL3 1857 2-0.0260.946146--
POLE4 56655 630.1770.82856--
RPSA 3921 1201.3271.151152Yes-
PSMB3 5691 640.6680.90119Yes-
PGD 5226 891.2011.106152Yes-
ACO2 50 651.0001.076191Yes-
PPP2R1A 5518 190.6440.985249Yes-
RPS11 6205 620.9931.113175Yes-
RPL14 9045 491.2501.113166Yes-
PSMB2 5690 1160.8770.956169Yes-
ACTB 60 1341.1531.151610Yes-
PSMD11 5717 1241.0951.106218Yes-
KPNB1 3837 170.6131.017296Yes-

Interactions (52)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMA1 5682 PSMB2 5690 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
PPP2R1A 5518 PSMB3 5691 pp -- int.I2D: IntAct_Mouse
ACTB 60 KPNB1 3837 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMB2 5690 POLE4 56655 pd < reg.ITFP.txt: no annot
PPP2R1A 5518 PSMA1 5682 pp -- int.I2D: IntAct_Mouse
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
ACO2 50 PSMD11 5717 pp -- int.I2D: YeastLow
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Yeast, YeastHigh, BioGrid_Yeast
RPSA 3921 VARS 7407 pp -- int.I2D: IntAct_Yeast
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
DVL3 1857 EIF4A1 1973 pp -- int.I2D: Jorgensen_EphR
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
PPP2R1A 5518 PSMB2 5690 pp -- int.I2D: IntAct_Mouse
ACTB 60 PPP2R1A 5518 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 RBX1 9978 pd < reg.ITFP.txt: no annot
PGD 5226 PSMD11 5717 pp -- int.I2D: YeastLow
VARS 7407 POLE4 56655 pd <> reg.ITFP.txt: no annot
PSMA2 5683 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PPP2R1A 5518 PSMB7 5695 pp -- int.I2D: IntAct_Mouse
EIF4A1 1973 PPP2R1A 5518 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
KPNB1 3837 PSMA2 5683 pp -- int.I2D: Krogan_NonCore, YeastLow
PSMA2 5683 POLE4 56655 pd < reg.ITFP.txt: no annot
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
ACO2 50 KPNB1 3837 pp -- int.I2D: IntAct_Yeast
DVL3 1857 RPS11 6205 pp -- int.I2D: Jorgensen_EphR
PSMB3 5691 PSMB7 5695 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS;
int.HPRD: yeast 2-hybrid
RPS11 6205 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
PGD 5226 PPP2R1A 5518 pp -- int.I2D: YeastLow
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
KPNB1 3837 PSMA1 5682 pp -- int.I2D: YeastLow
ACO2 50 PGD 5226 pp -- int.I2D: YeastLow
PSMB3 5691 POLE4 56655 pd < reg.ITFP.txt: no annot
DVL3 1857 KPNB1 3837 pp -- int.I2D: Jorgensen_EphR
PPP2R1A 5518 PSMA2 5683 pp -- int.I2D: IntAct_Mouse
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
DVL3 1857 PPP2R1A 5518 pp -- int.I2D: Jorgensen_EphR
PSMB2 5690 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB2 5690 VARS 7407 pd < reg.ITFP.txt: no annot
PSMB3 5691 PSMD11 5717 pp -- int.I2D: YeastLow
KPNB1 3837 PSMD11 5717 pp -- int.I2D: Krogan_NonCore
RPSA 3921 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA2 5683 PSMB2 5690 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core

Related GO terms (242)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0016071mRNA metabolic process1.66e-162.71e-125.4051134223
GO:0016070RNA metabolic process5.19e-168.46e-125.2581134247
GO:0016032viral process6.23e-141.02e-094.2551255540
GO:0010467gene expression7.91e-131.29e-083.9461258669
GO:0005839proteasome core complex1.02e-111.67e-077.89951118
GO:0006521regulation of cellular amino acid metabolic process1.60e-112.60e-076.68862150
GO:0004298threonine-type endopeptidase activity1.85e-113.02e-077.74751120
GO:0000502proteasome complex4.04e-116.60e-076.47362258
GO:0005829cytosol7.86e-111.28e-062.423161252562
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle8.21e-111.34e-066.30962465
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest8.21e-111.34e-066.30962265
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.30e-102.12e-066.20262470
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent1.68e-102.75e-066.14262373
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.83e-102.99e-066.12262474
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I2.34e-103.81e-066.06562377
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process2.74e-104.46e-066.02862579
GO:0002474antigen processing and presentation of peptide antigen via MHC class I7.93e-101.29e-055.77762394
GO:0000209protein polyubiquitination2.85e-094.65e-055.473621116
GO:0000082G1/S transition of mitotic cell cycle1.34e-082.19e-045.103633150
GO:0042981regulation of apoptotic process1.39e-082.28e-045.093626151
GO:0070062extracellular vesicular exosome2.23e-083.64e-042.25714982516
GO:0034641cellular nitrogen compound metabolic process3.61e-085.89e-044.864625177
GO:0006915apoptotic process1.15e-071.88e-033.589834571
GO:0000278mitotic cell cycle1.90e-073.11e-033.917752398
GO:0005654nucleoplasm1.33e-062.17e-022.8209831095
GO:0044281small molecule metabolic process5.39e-068.80e-022.5789571295
GO:0043066negative regulation of apoptotic process6.81e-061.11e-013.573630433
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay8.07e-061.32e-014.914410114
GO:0019058viral life cycle8.36e-061.36e-014.901410115
GO:0006413translational initiation1.40e-052.28e-014.713412131
GO:0019773proteasome core complex, alpha-subunit complex3.58e-055.84e-017.747258
GO:0005515protein binding4.05e-056.61e-011.166161726127
GO:0016020membrane6.11e-059.97e-012.1479801746
GO:0019083viral transcription1.08e-041.00e+004.9923881
GO:0006415translational termination1.33e-041.00e+004.8893887
GO:0006412translation1.37e-041.00e+003.870415235
GO:0006414translational elongation1.62e-041.00e+004.79231193
GO:0044267cellular protein metabolic process2.06e-041.00e+003.117524495
GO:0006614SRP-dependent cotranslational protein targeting to membrane2.26e-041.00e+004.63138104
GO:0003735structural constituent of ribosome5.53e-041.00e+004.19238141
GO:0022627cytosolic small ribosomal subunit9.27e-041.00e+005.4612339
GO:0070262peptidyl-serine dephosphorylation1.16e-031.00e+009.747111
GO:0019521D-gluconate metabolic process1.16e-031.00e+009.747111
GO:0004832valine-tRNA ligase activity2.33e-031.00e+008.747112
GO:00515383 iron, 4 sulfur cluster binding2.33e-031.00e+008.747112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2.33e-031.00e+008.747112
GO:0019322pentose biosynthetic process2.33e-031.00e+008.747112
GO:0003994aconitate hydratase activity2.33e-031.00e+008.747112
GO:0005055laminin receptor activity2.33e-031.00e+008.747112
GO:0006407rRNA export from nucleus2.33e-031.00e+008.747112
GO:0006438valyl-tRNA aminoacylation2.33e-031.00e+008.747112
GO:0005634nucleus2.46e-031.00e+001.094121314828
GO:0009051pentose-phosphate shunt, oxidative branch3.49e-031.00e+008.162113
GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity3.49e-031.00e+008.162113
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)4.65e-031.00e+007.747114
GO:003068690S preribosome4.65e-031.00e+007.747114
GO:0031467Cul7-RING ubiquitin ligase complex4.65e-031.00e+007.747114
GO:0019788NEDD8 ligase activity4.65e-031.00e+007.747114
GO:0006610ribosomal protein import into nucleus4.65e-031.00e+007.747114
GO:0071782endoplasmic reticulum tubular network4.65e-031.00e+007.747114
GO:0031465Cul4B-RING E3 ubiquitin ligase complex5.81e-031.00e+007.425125
GO:0031461cullin-RING ubiquitin ligase complex5.81e-031.00e+007.425115
GO:0019932second-messenger-mediated signaling5.81e-031.00e+007.425115
GO:0043248proteasome assembly5.81e-031.00e+007.425115
GO:0042518negative regulation of tyrosine phosphorylation of Stat3 protein5.81e-031.00e+007.425115
GO:0006102isocitrate metabolic process5.81e-031.00e+007.425115
GO:0030891VCB complex5.81e-031.00e+007.425125
GO:0038031non-canonical Wnt signaling pathway via JNK cascade5.81e-031.00e+007.425115
GO:0035567non-canonical Wnt signaling pathway5.81e-031.00e+007.425115
GO:0008622epsilon DNA polymerase complex5.81e-031.00e+007.425115
GO:0060026convergent extension5.81e-031.00e+007.425115
GO:0044822poly(A) RNA binding6.64e-031.00e+001.9945501078
GO:0030957Tat protein binding6.97e-031.00e+007.162146
GO:0006101citrate metabolic process6.97e-031.00e+007.162116
GO:0031466Cul5-RING ubiquitin ligase complex6.97e-031.00e+007.162116
GO:0015630microtubule cytoskeleton7.40e-031.00e+003.93925112
GO:0000028ribosomal small subunit assembly8.12e-031.00e+006.939117
GO:0002161aminoacyl-tRNA editing activity8.12e-031.00e+006.939127
GO:0031462Cul2-RING ubiquitin ligase complex8.12e-031.00e+006.939127
GO:0031464Cul4A-RING E3 ubiquitin ligase complex9.28e-031.00e+006.747128
GO:0000339RNA cap binding9.28e-031.00e+006.747118
GO:0070688MLL5-L complex9.28e-031.00e+006.747118
GO:0045116protein neddylation9.28e-031.00e+006.747128
GO:0008139nuclear localization sequence binding1.04e-021.00e+006.577129
GO:0016281eukaryotic translation initiation factor 4F complex1.04e-021.00e+006.577119
GO:0046982protein heterodimerization activity1.05e-021.00e+002.691311399
GO:0006450regulation of translational fidelity1.16e-021.00e+006.4251210
GO:0007084mitotic nuclear envelope reassembly1.16e-021.00e+006.4251110
GO:0006098pentose-phosphate shunt1.27e-021.00e+006.2871311
GO:0060071Wnt signaling pathway, planar cell polarity pathway1.27e-021.00e+006.2871211
GO:0006275regulation of DNA replication1.39e-021.00e+006.1621212
GO:0030111regulation of Wnt signaling pathway1.39e-021.00e+006.1621112
GO:0005838proteasome regulatory particle1.39e-021.00e+006.1621712
GO:0042273ribosomal large subunit biogenesis1.50e-021.00e+006.0461413
GO:0090179planar cell polarity pathway involved in neural tube closure1.50e-021.00e+006.0461113
GO:0035267NuA4 histone acetyltransferase complex1.62e-021.00e+005.9391414
GO:0003148outflow tract septum morphogenesis1.62e-021.00e+005.9391114
GO:0006607NLS-bearing protein import into nucleus1.62e-021.00e+005.9391214
GO:0006672ceramide metabolic process1.73e-021.00e+005.8401115
GO:0005671Ada2/Gcn5/Ada3 transcription activator complex1.73e-021.00e+005.8401115
GO:2001241positive regulation of extrinsic apoptotic signaling pathway in absence of ligand1.73e-021.00e+005.8401215
GO:0050998nitric-oxide synthase binding1.85e-021.00e+005.7471116
GO:0075733intracellular transport of virus1.96e-021.00e+005.6591217
GO:0010243response to organonitrogen compound1.96e-021.00e+005.6591217
GO:0006309apoptotic DNA fragmentation1.96e-021.00e+005.6591117
GO:0022624proteasome accessory complex1.96e-021.00e+005.6591917
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process2.19e-021.00e+005.4991119
GO:0048863stem cell differentiation2.19e-021.00e+005.4991119
GO:0008601protein phosphatase type 2A regulator activity2.30e-021.00e+005.4251320
GO:0000159protein phosphatase type 2A complex2.30e-021.00e+005.4251220
GO:0090103cochlea morphogenesis2.42e-021.00e+005.3541221
GO:0045595regulation of cell differentiation2.42e-021.00e+005.3541121
GO:0030863cortical cytoskeleton2.53e-021.00e+005.2871122
GO:0036464cytoplasmic ribonucleoprotein granule2.53e-021.00e+005.2871422
GO:0043044ATP-dependent chromatin remodeling2.65e-021.00e+005.2231423
GO:0031463Cul3-RING ubiquitin ligase complex2.65e-021.00e+005.2231223
GO:0043236laminin binding2.65e-021.00e+005.2231123
GO:0006513protein monoubiquitination2.65e-021.00e+005.2231123
GO:0008135translation factor activity, nucleic acid binding2.76e-021.00e+005.1621424
GO:0000060protein import into nucleus, translocation2.76e-021.00e+005.1621424
GO:0008536Ran GTPase binding2.87e-021.00e+005.1031225
GO:0005844polysome2.87e-021.00e+005.1031425
GO:0000289nuclear-transcribed mRNA poly(A) tail shortening2.87e-021.00e+005.1031125
GO:0019221cytokine-mediated signaling pathway2.89e-021.00e+002.90123230
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia2.99e-021.00e+005.0461226
GO:0005739mitochondrion3.00e-021.00e+001.7164241046
GO:0019843rRNA binding3.10e-021.00e+004.9921327
GO:0000188inactivation of MAPK activity3.10e-021.00e+004.9921127
GO:0003823antigen binding3.21e-021.00e+004.9391128
GO:0010033response to organic substance3.21e-021.00e+004.9391228
GO:0043022ribosome binding3.21e-021.00e+004.9391328
GO:0043507positive regulation of JUN kinase activity3.21e-021.00e+004.9391228
GO:0031492nucleosomal DNA binding3.21e-021.00e+004.9391428
GO:0019894kinesin binding3.21e-021.00e+004.9391128
GO:0006099tricarboxylic acid cycle3.32e-021.00e+004.8891329
GO:0019005SCF ubiquitin ligase complex3.32e-021.00e+004.8891129
GO:0003887DNA-directed DNA polymerase activity3.32e-021.00e+004.8891329
GO:0071897DNA biosynthetic process3.32e-021.00e+004.8891229
GO:0006606protein import into nucleus3.44e-021.00e+004.8401130
GO:0005109frizzled binding3.66e-021.00e+004.7471132
GO:0050661NADP binding3.66e-021.00e+004.7471132
GO:0034332adherens junction organization4.11e-021.00e+004.5771136
GO:0001895retina homeostasis4.11e-021.00e+004.5771136
GO:0051084'de novo' posttranslational protein folding4.22e-021.00e+004.5371437
GO:00515394 iron, 4 sulfur cluster binding4.22e-021.00e+004.5371337
GO:0070527platelet aggregation4.33e-021.00e+004.4991238
GO:0008026ATP-dependent helicase activity4.45e-021.00e+004.4611339
GO:0006418tRNA aminoacylation for protein translation4.78e-021.00e+004.3541542
GO:0004722protein serine/threonine phosphatase activity4.78e-021.00e+004.3541142
GO:0030155regulation of cell adhesion4.78e-021.00e+004.3541342
GO:0014070response to organic cyclic compound4.89e-021.00e+004.3201343
GO:0043966histone H3 acetylation5.11e-021.00e+004.2551245
GO:0021762substantia nigra development5.22e-021.00e+004.2231146
GO:0006921cellular component disassembly involved in execution phase of apoptosis5.33e-021.00e+004.1921547
GO:0022625cytosolic large ribosomal subunit5.56e-021.00e+004.1321549
GO:0003743translation initiation factor activity5.56e-021.00e+004.1321449
GO:0031100organ regeneration5.67e-021.00e+004.1031450
GO:0006091generation of precursor metabolites and energy5.78e-021.00e+004.0741351
GO:0040008regulation of growth5.78e-021.00e+004.0741351
GO:0000775chromosome, centromeric region5.89e-021.00e+004.0461252
GO:0000288nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay6.00e-021.00e+004.0191153
GO:0003725double-stranded RNA binding6.11e-021.00e+003.9921654
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding6.11e-021.00e+003.9921554
GO:0003723RNA binding6.33e-021.00e+002.275219355
GO:0004386helicase activity6.33e-021.00e+003.9391456
GO:0000932cytoplasmic mRNA processing body6.33e-021.00e+003.9391356
GO:0008565protein transporter activity6.43e-021.00e+003.9141257
GO:0005840ribosome6.65e-021.00e+003.8641259
GO:0045216cell-cell junction organization6.65e-021.00e+003.8641259
GO:0005643nuclear pore6.65e-021.00e+003.8641459
GO:0008013beta-catenin binding6.76e-021.00e+003.8401460
GO:0005925focal adhesion6.80e-021.00e+002.215218370
GO:0007059chromosome segregation7.20e-021.00e+003.7471364
GO:0034329cell junction assembly7.95e-021.00e+003.5971171
GO:0003729mRNA binding8.17e-021.00e+003.5571473
GO:0002020protease binding8.28e-021.00e+003.5371474
GO:0060070canonical Wnt signaling pathway8.38e-021.00e+003.5181375
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process8.49e-021.00e+003.4991376
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis8.60e-021.00e+003.4801577
GO:0006928cellular component movement1.02e-011.00e+003.2231792
GO:0005200structural constituent of cytoskeleton1.03e-011.00e+003.2071793
GO:0001649osteoblast differentiation1.05e-011.00e+003.1771695
GO:0006364rRNA processing1.06e-011.00e+003.1621596
GO:0071456cellular response to hypoxia1.08e-011.00e+003.1321498
GO:0006470protein dephosphorylation1.09e-011.00e+003.1171199
GO:0014069postsynaptic density1.17e-011.00e+003.01911106
GO:0001934positive regulation of protein phosphorylation1.19e-011.00e+002.99215108
GO:0005938cell cortex1.20e-011.00e+002.97813109
GO:0006461protein complex assembly1.22e-011.00e+002.95216111
GO:0030308negative regulation of cell growth1.24e-011.00e+002.92616113
GO:0005730nucleolus1.25e-011.00e+001.0294701684
GO:0030529ribonucleoprotein complex1.25e-011.00e+002.91418114
GO:0072562blood microparticle1.27e-011.00e+002.88914116
GO:0005635nuclear envelope1.27e-011.00e+002.88916116
GO:0044237cellular metabolic process1.29e-011.00e+002.86413118
GO:0006325chromatin organization1.34e-011.00e+002.80414123
GO:0007219Notch signaling pathway1.36e-011.00e+002.78114125
GO:0005506iron ion binding1.38e-011.00e+002.75813127
GO:0006511ubiquitin-dependent protein catabolic process1.38e-011.00e+002.75815127
GO:0009615response to virus1.43e-011.00e+002.70216132
GO:0000790nuclear chromatin1.44e-011.00e+002.69117133
GO:0000086G2/M transition of mitotic cell cycle1.48e-011.00e+002.64817137
GO:0016055Wnt signaling pathway1.52e-011.00e+002.60716141
GO:0061024membrane organization1.57e-011.00e+002.55715146
GO:0006457protein folding1.60e-011.00e+002.52718149
GO:0008543fibroblast growth factor receptor signaling pathway1.70e-011.00e+002.43414159
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding1.79e-011.00e+002.35415168
GO:0030424axon1.82e-011.00e+002.32013172
GO:0031965nuclear membrane1.86e-011.00e+002.28714176
GO:0031625ubiquitin protein ligase binding1.90e-011.00e+002.255113180
GO:0019904protein domain specific binding1.91e-011.00e+002.24716181
GO:0015629actin cytoskeleton1.93e-011.00e+002.23115183
GO:0032403protein complex binding1.95e-011.00e+002.21517185
GO:0005524ATP binding2.05e-011.00e+000.9283461354
GO:0008380RNA splicing2.38e-011.00e+001.889113232
GO:0005759mitochondrial matrix2.39e-011.00e+001.882112233
GO:0004842ubiquitin-protein transferase activity2.60e-011.00e+001.74714256
GO:0006281DNA repair2.67e-011.00e+001.702122264
GO:0005102receptor binding2.70e-011.00e+001.68015268
GO:0005975carbohydrate metabolic process2.75e-011.00e+001.64815274
GO:0042493response to drug2.87e-011.00e+001.577111288
GO:0019899enzyme binding2.87e-011.00e+001.577111288
GO:0016567protein ubiquitination2.96e-011.00e+001.52315299
GO:0043234protein complex2.97e-011.00e+001.518117300
GO:0006200ATP catabolic process3.00e-011.00e+001.503114303
GO:0005856cytoskeleton3.06e-011.00e+001.46618311
GO:0035556intracellular signal transduction3.11e-011.00e+001.43816317
GO:0019901protein kinase binding3.14e-011.00e+001.425121320
GO:0007411axon guidance3.19e-011.00e+001.39319327
GO:0005813centrosome3.29e-011.00e+001.341112339
GO:0043565sequence-specific DNA binding3.49e-011.00e+001.23514365
GO:0008270zinc ion binding3.55e-011.00e+000.6872121067
GO:0007155cell adhesion3.64e-011.00e+001.16218384
GO:0007596blood coagulation4.22e-011.00e+000.889114464
GO:0055114oxidation-reduction process4.34e-011.00e+000.837111481
GO:0045893positive regulation of transcription, DNA-templated4.38e-011.00e+000.819117487
GO:0005737cytoplasm5.09e-011.00e+000.1115983976
GO:0045087innate immune response5.19e-011.00e+000.480120616
GO:0005794Golgi apparatus5.38e-011.00e+000.402114650
GO:0005615extracellular space7.03e-011.00e+00-0.2341171010
GO:0006355regulation of transcription, DNA-templated7.36e-011.00e+00-0.3621171104
GO:0005886plasma membrane9.73e-011.00e+00-1.7221382834