Subnetwork | Dataset | Score | p-value 1 | p-value 2 | p-value 3 | Size | Highlighted genes |
---|---|---|---|---|---|---|---|
reg-snw-5925 | wolf-screen-ratio-mammosphere-adherent | 0.802 | 2.42e-06 | 4.82e-03 | 8.69e-03 | 8 | 5 |
int-snw-1072 | wolf-screen-ratio-mammosphere-adherent | 1.002 | 3.18e-18 | 5.23e-04 | 1.26e-02 | 7 | 7 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
RPA2 | 6118 | 96 | 1.250 | 1.151 | 76 | Yes | - |
ACO2 | 50 | 65 | 1.000 | 1.076 | 191 | Yes | - |
RSL24D1 | 51187 | 38 | 1.300 | 1.020 | 59 | Yes | - |
RB1 | 5925 | 31 | -0.102 | 0.802 | 351 | - | - |
ATP1A1 | 476 | 2 | 0.842 | 1.002 | 82 | Yes | - |
PPCS | 79717 | 31 | -0.569 | 0.802 | 2 | - | Yes |
PPIE | 10450 | 31 | 0.567 | 0.802 | 41 | - | - |
ACTB | 60 | 134 | 1.153 | 1.151 | 610 | Yes | - |
OGDH | 4967 | 72 | 0.847 | 0.802 | 126 | Yes | - |
TFRC | 7037 | 31 | 0.730 | 0.802 | 17 | - | - |
CFL1 | 1072 | 18 | 0.674 | 1.020 | 203 | Yes | - |
PGD | 5226 | 89 | 1.201 | 1.106 | 152 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
ACO2 | 50 | CFL1 | 1072 | pp | -- | int.I2D: YeastLow |
ACO2 | 50 | OGDH | 4967 | pp | -- | int.I2D: YeastLow |
RB1 | 5925 | PPCS | 79717 | pd | > | reg.pazar.txt: no annot |
RB1 | 5925 | RPA2 | 6118 | pd | > | reg.pazar.txt: no annot |
PGD | 5226 | RB1 | 5925 | pd | < | reg.pazar.txt: no annot |
OGDH | 4967 | RB1 | 5925 | pd | < | reg.ITFP.txt: no annot |
ACTB | 60 | CFL1 | 1072 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, MINT_Yeast, MIPS, BioGrid, BIND_Yeast, HPRD, IntAct, IntAct_Yeast, MINT, VidalHuman_core, YeastLow, Yu_GoldStd; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid |
OGDH | 4967 | PGD | 5226 | pp | -- | int.I2D: YeastLow |
ACTB | 60 | RB1 | 5925 | pd | < | reg.ITFP.txt: no annot |
CFL1 | 1072 | PGD | 5226 | pp | -- | int.I2D: YeastLow |
ACTB | 60 | RPA2 | 6118 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
ATP1A1 | 476 | CFL1 | 1072 | pp | -- | int.I2D: BCI, BioGrid_Rat, HPRD; int.HPRD: in vitro, in vivo, yeast 2-hybrid |
ACO2 | 50 | PGD | 5226 | pp | -- | int.I2D: YeastLow |
CFL1 | 1072 | OGDH | 4967 | pp | -- | int.I2D: YeastLow |
RB1 | 5925 | TFRC | 7037 | pd | > | reg.ITFP.txt: no annot |
CFL1 | 1072 | RSL24D1 | 51187 | pp | -- | int.I2D: YeastLow |
RB1 | 5925 | PPIE | 10450 | pd | > | reg.pazar.txt: no annot |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0031982 | vesicle | 1.13e-04 | 1.00e+00 | 4.928 | 3 | 10 | 134 |
GO:0006099 | tricarboxylic acid cycle | 1.99e-04 | 1.00e+00 | 6.551 | 2 | 3 | 29 |
GO:0006091 | generation of precursor metabolites and energy | 6.19e-04 | 1.00e+00 | 5.737 | 2 | 3 | 51 |
GO:0045989 | positive regulation of striated muscle contraction | 7.35e-04 | 1.00e+00 | 10.409 | 1 | 1 | 1 |
GO:0034602 | oxoglutarate dehydrogenase (NAD+) activity | 7.35e-04 | 1.00e+00 | 10.409 | 1 | 1 | 1 |
GO:0090230 | regulation of centromere complex assembly | 7.35e-04 | 1.00e+00 | 10.409 | 1 | 1 | 1 |
GO:0004632 | phosphopantothenate--cysteine ligase activity | 7.35e-04 | 1.00e+00 | 10.409 | 1 | 1 | 1 |
GO:0019521 | D-gluconate metabolic process | 7.35e-04 | 1.00e+00 | 10.409 | 1 | 1 | 1 |
GO:0031947 | negative regulation of glucocorticoid biosynthetic process | 7.35e-04 | 1.00e+00 | 10.409 | 1 | 1 | 1 |
GO:0051087 | chaperone binding | 8.28e-04 | 1.00e+00 | 5.527 | 2 | 6 | 59 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 1.41e-03 | 1.00e+00 | 5.143 | 2 | 5 | 77 |
GO:0045252 | oxoglutarate dehydrogenase complex | 1.47e-03 | 1.00e+00 | 9.409 | 1 | 2 | 2 |
GO:0051538 | 3 iron, 4 sulfur cluster binding | 1.47e-03 | 1.00e+00 | 9.409 | 1 | 1 | 2 |
GO:0003994 | aconitate hydratase activity | 1.47e-03 | 1.00e+00 | 9.409 | 1 | 1 | 2 |
GO:0097286 | iron ion import | 1.47e-03 | 1.00e+00 | 9.409 | 1 | 1 | 2 |
GO:0061034 | olfactory bulb mitral cell layer development | 1.47e-03 | 1.00e+00 | 9.409 | 1 | 1 | 2 |
GO:0004998 | transferrin receptor activity | 1.47e-03 | 1.00e+00 | 9.409 | 1 | 1 | 2 |
GO:0019322 | pentose biosynthetic process | 1.47e-03 | 1.00e+00 | 9.409 | 1 | 1 | 2 |
GO:0031134 | sister chromatid biorientation | 1.47e-03 | 1.00e+00 | 9.409 | 1 | 1 | 2 |
GO:0007070 | negative regulation of transcription from RNA polymerase II promoter during mitosis | 1.47e-03 | 1.00e+00 | 9.409 | 1 | 2 | 2 |
GO:0016605 | PML body | 2.00e-03 | 1.00e+00 | 4.886 | 2 | 5 | 92 |
GO:0042470 | melanosome | 2.00e-03 | 1.00e+00 | 4.886 | 2 | 10 | 92 |
GO:1990239 | steroid hormone binding | 2.20e-03 | 1.00e+00 | 8.825 | 1 | 1 | 3 |
GO:1903416 | response to glycoside | 2.20e-03 | 1.00e+00 | 8.825 | 1 | 1 | 3 |
GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity | 2.20e-03 | 1.00e+00 | 8.825 | 1 | 1 | 3 |
GO:0022028 | tangential migration from the subventricular zone to the olfactory bulb | 2.20e-03 | 1.00e+00 | 8.825 | 1 | 1 | 3 |
GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity | 2.20e-03 | 1.00e+00 | 8.825 | 1 | 1 | 3 |
GO:0071459 | protein localization to chromosome, centromeric region | 2.20e-03 | 1.00e+00 | 8.825 | 1 | 1 | 3 |
GO:0009051 | pentose-phosphate shunt, oxidative branch | 2.20e-03 | 1.00e+00 | 8.825 | 1 | 1 | 3 |
GO:0071930 | negative regulation of transcription involved in G1/S transition of mitotic cell cycle | 2.20e-03 | 1.00e+00 | 8.825 | 1 | 1 | 3 |
GO:0071922 | regulation of cohesin localization to chromatin | 2.94e-03 | 1.00e+00 | 8.409 | 1 | 1 | 4 |
GO:0001842 | neural fold formation | 2.94e-03 | 1.00e+00 | 8.409 | 1 | 1 | 4 |
GO:0006104 | succinyl-CoA metabolic process | 2.94e-03 | 1.00e+00 | 8.409 | 1 | 1 | 4 |
GO:0043550 | regulation of lipid kinase activity | 2.94e-03 | 1.00e+00 | 8.409 | 1 | 1 | 4 |
GO:0035189 | Rb-E2F complex | 2.94e-03 | 1.00e+00 | 8.409 | 1 | 1 | 4 |
GO:0034088 | maintenance of mitotic sister chromatid cohesion | 2.94e-03 | 1.00e+00 | 8.409 | 1 | 1 | 4 |
GO:0034349 | glial cell apoptotic process | 2.94e-03 | 1.00e+00 | 8.409 | 1 | 1 | 4 |
GO:0072562 | blood microparticle | 3.16e-03 | 1.00e+00 | 4.551 | 2 | 4 | 116 |
GO:0044237 | cellular metabolic process | 3.26e-03 | 1.00e+00 | 4.527 | 2 | 3 | 118 |
GO:2000001 | regulation of DNA damage checkpoint | 3.67e-03 | 1.00e+00 | 8.088 | 1 | 1 | 5 |
GO:0048667 | cell morphogenesis involved in neuron differentiation | 3.67e-03 | 1.00e+00 | 8.088 | 1 | 1 | 5 |
GO:0006102 | isocitrate metabolic process | 3.67e-03 | 1.00e+00 | 8.088 | 1 | 1 | 5 |
GO:0031402 | sodium ion binding | 3.67e-03 | 1.00e+00 | 8.088 | 1 | 1 | 5 |
GO:0000730 | DNA recombinase assembly | 3.67e-03 | 1.00e+00 | 8.088 | 1 | 3 | 5 |
GO:0006734 | NADH metabolic process | 3.67e-03 | 1.00e+00 | 8.088 | 1 | 1 | 5 |
GO:0030976 | thiamine pyrophosphate binding | 3.67e-03 | 1.00e+00 | 8.088 | 1 | 1 | 5 |
GO:0045823 | positive regulation of heart contraction | 3.67e-03 | 1.00e+00 | 8.088 | 1 | 1 | 5 |
GO:0043353 | enucleate erythrocyte differentiation | 4.40e-03 | 1.00e+00 | 7.825 | 1 | 1 | 6 |
GO:0009108 | coenzyme biosynthetic process | 4.40e-03 | 1.00e+00 | 7.825 | 1 | 1 | 6 |
GO:0045822 | negative regulation of heart contraction | 4.40e-03 | 1.00e+00 | 7.825 | 1 | 1 | 6 |
GO:0045842 | positive regulation of mitotic metaphase/anaphase transition | 4.40e-03 | 1.00e+00 | 7.825 | 1 | 1 | 6 |
GO:0006101 | citrate metabolic process | 4.40e-03 | 1.00e+00 | 7.825 | 1 | 1 | 6 |
GO:0021860 | pyramidal neuron development | 4.40e-03 | 1.00e+00 | 7.825 | 1 | 1 | 6 |
GO:0036376 | sodium ion export from cell | 4.40e-03 | 1.00e+00 | 7.825 | 1 | 1 | 6 |
GO:0021695 | cerebellar cortex development | 4.40e-03 | 1.00e+00 | 7.825 | 1 | 1 | 6 |
GO:0030957 | Tat protein binding | 4.40e-03 | 1.00e+00 | 7.825 | 1 | 4 | 6 |
GO:0086013 | membrane repolarization during cardiac muscle cell action potential | 5.14e-03 | 1.00e+00 | 7.602 | 1 | 1 | 7 |
GO:0030836 | positive regulation of actin filament depolymerization | 5.14e-03 | 1.00e+00 | 7.602 | 1 | 2 | 7 |
GO:0016018 | cyclosporin A binding | 5.14e-03 | 1.00e+00 | 7.602 | 1 | 1 | 7 |
GO:0006457 | protein folding | 5.15e-03 | 1.00e+00 | 4.190 | 2 | 8 | 149 |
GO:0000082 | G1/S transition of mitotic cell cycle | 5.21e-03 | 1.00e+00 | 4.181 | 2 | 33 | 150 |
GO:0070062 | extracellular vesicular exosome | 5.32e-03 | 1.00e+00 | 1.698 | 6 | 98 | 2516 |
GO:0070688 | MLL5-L complex | 5.87e-03 | 1.00e+00 | 7.409 | 1 | 1 | 8 |
GO:0006554 | lysine catabolic process | 5.87e-03 | 1.00e+00 | 7.409 | 1 | 2 | 8 |
GO:0030955 | potassium ion binding | 5.87e-03 | 1.00e+00 | 7.409 | 1 | 1 | 8 |
GO:0005391 | sodium:potassium-exchanging ATPase activity | 5.87e-03 | 1.00e+00 | 7.409 | 1 | 1 | 8 |
GO:0086009 | membrane repolarization | 5.87e-03 | 1.00e+00 | 7.409 | 1 | 1 | 8 |
GO:0030042 | actin filament depolymerization | 5.87e-03 | 1.00e+00 | 7.409 | 1 | 2 | 8 |
GO:0015937 | coenzyme A biosynthetic process | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 1 | 9 |
GO:0097284 | hepatocyte apoptotic process | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 2 | 9 |
GO:0030007 | cellular potassium ion homeostasis | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 1 | 9 |
GO:0000075 | cell cycle checkpoint | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 2 | 9 |
GO:0005768 | endosome | 6.95e-03 | 1.00e+00 | 3.967 | 2 | 5 | 174 |
GO:0071383 | cellular response to steroid hormone stimulus | 7.33e-03 | 1.00e+00 | 7.088 | 1 | 1 | 10 |
GO:0015939 | pantothenate metabolic process | 7.33e-03 | 1.00e+00 | 7.088 | 1 | 1 | 10 |
GO:0005890 | sodium:potassium-exchanging ATPase complex | 7.33e-03 | 1.00e+00 | 7.088 | 1 | 1 | 10 |
GO:0021756 | striatum development | 7.33e-03 | 1.00e+00 | 7.088 | 1 | 1 | 10 |
GO:0031625 | ubiquitin protein ligase binding | 7.42e-03 | 1.00e+00 | 3.918 | 2 | 13 | 180 |
GO:0006098 | pentose-phosphate shunt | 8.06e-03 | 1.00e+00 | 6.950 | 1 | 3 | 11 |
GO:0010569 | regulation of double-strand break repair via homologous recombination | 8.06e-03 | 1.00e+00 | 6.950 | 1 | 1 | 11 |
GO:0031571 | mitotic G1 DNA damage checkpoint | 8.06e-03 | 1.00e+00 | 6.950 | 1 | 3 | 11 |
GO:0042551 | neuron maturation | 8.06e-03 | 1.00e+00 | 6.950 | 1 | 2 | 11 |
GO:0061001 | regulation of dendritic spine morphogenesis | 8.06e-03 | 1.00e+00 | 6.950 | 1 | 2 | 11 |
GO:0045651 | positive regulation of macrophage differentiation | 8.06e-03 | 1.00e+00 | 6.950 | 1 | 2 | 11 |
GO:0086004 | regulation of cardiac muscle cell contraction | 8.06e-03 | 1.00e+00 | 6.950 | 1 | 1 | 11 |
GO:0006883 | cellular sodium ion homeostasis | 8.79e-03 | 1.00e+00 | 6.825 | 1 | 1 | 12 |
GO:0051146 | striated muscle cell differentiation | 8.79e-03 | 1.00e+00 | 6.825 | 1 | 1 | 12 |
GO:0060081 | membrane hyperpolarization | 8.79e-03 | 1.00e+00 | 6.825 | 1 | 1 | 12 |
GO:0021794 | thalamus development | 8.79e-03 | 1.00e+00 | 6.825 | 1 | 1 | 12 |
GO:0086064 | cell communication by electrical coupling involved in cardiac conduction | 8.79e-03 | 1.00e+00 | 6.825 | 1 | 1 | 12 |
GO:0055119 | relaxation of cardiac muscle | 8.79e-03 | 1.00e+00 | 6.825 | 1 | 1 | 12 |
GO:0010107 | potassium ion import | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 13 |
GO:0002028 | regulation of sodium ion transport | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 13 |
GO:0005662 | DNA replication factor A complex | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 3 | 13 |
GO:0045780 | positive regulation of bone resorption | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 13 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.02e-02 | 1.00e+00 | 6.602 | 1 | 4 | 14 |
GO:0045445 | myoblast differentiation | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 2 | 15 |
GO:0016514 | SWI/SNF complex | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 3 | 15 |
GO:0044281 | small molecule metabolic process | 1.16e-02 | 1.00e+00 | 2.071 | 4 | 57 | 1295 |
GO:0050998 | nitric-oxide synthase binding | 1.17e-02 | 1.00e+00 | 6.409 | 1 | 1 | 16 |
GO:0006103 | 2-oxoglutarate metabolic process | 1.17e-02 | 1.00e+00 | 6.409 | 1 | 1 | 16 |
GO:0005759 | mitochondrial matrix | 1.22e-02 | 1.00e+00 | 3.545 | 2 | 12 | 233 |
GO:0045070 | positive regulation of viral genome replication | 1.24e-02 | 1.00e+00 | 6.322 | 1 | 1 | 17 |
GO:0031258 | lamellipodium membrane | 1.24e-02 | 1.00e+00 | 6.322 | 1 | 2 | 17 |
GO:0002026 | regulation of the force of heart contraction | 1.24e-02 | 1.00e+00 | 6.322 | 1 | 1 | 17 |
GO:0022604 | regulation of cell morphogenesis | 1.24e-02 | 1.00e+00 | 6.322 | 1 | 1 | 17 |
GO:0035861 | site of double-strand break | 1.32e-02 | 1.00e+00 | 6.240 | 1 | 1 | 18 |
GO:0016791 | phosphatase activity | 1.32e-02 | 1.00e+00 | 6.240 | 1 | 1 | 18 |
GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle | 1.46e-02 | 1.00e+00 | 6.088 | 1 | 2 | 20 |
GO:0006754 | ATP biosynthetic process | 1.46e-02 | 1.00e+00 | 6.088 | 1 | 1 | 20 |
GO:0006298 | mismatch repair | 1.46e-02 | 1.00e+00 | 6.088 | 1 | 6 | 20 |
GO:0030010 | establishment of cell polarity | 1.53e-02 | 1.00e+00 | 6.017 | 1 | 2 | 21 |
GO:0000718 | nucleotide-excision repair, DNA damage removal | 1.53e-02 | 1.00e+00 | 6.017 | 1 | 5 | 21 |
GO:0043548 | phosphatidylinositol 3-kinase binding | 1.53e-02 | 1.00e+00 | 6.017 | 1 | 1 | 21 |
GO:0030506 | ankyrin binding | 1.53e-02 | 1.00e+00 | 6.017 | 1 | 1 | 21 |
GO:0000281 | mitotic cytokinesis | 1.53e-02 | 1.00e+00 | 6.017 | 1 | 2 | 21 |
GO:0030316 | osteoclast differentiation | 1.61e-02 | 1.00e+00 | 5.950 | 1 | 2 | 22 |
GO:0006297 | nucleotide-excision repair, DNA gap filling | 1.61e-02 | 1.00e+00 | 5.950 | 1 | 5 | 22 |
GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle | 1.61e-02 | 1.00e+00 | 5.950 | 1 | 3 | 22 |
GO:0032201 | telomere maintenance via semi-conservative replication | 1.61e-02 | 1.00e+00 | 5.950 | 1 | 7 | 22 |
GO:0030863 | cortical cytoskeleton | 1.61e-02 | 1.00e+00 | 5.950 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 1.61e-02 | 1.00e+00 | 5.950 | 1 | 4 | 22 |
GO:0043200 | response to amino acid | 1.68e-02 | 1.00e+00 | 5.886 | 1 | 1 | 23 |
GO:0043044 | ATP-dependent chromatin remodeling | 1.68e-02 | 1.00e+00 | 5.886 | 1 | 4 | 23 |
GO:0045879 | negative regulation of smoothened signaling pathway | 1.68e-02 | 1.00e+00 | 5.886 | 1 | 1 | 23 |
GO:0030864 | cortical actin cytoskeleton | 1.82e-02 | 1.00e+00 | 5.766 | 1 | 1 | 25 |
GO:0000722 | telomere maintenance via recombination | 1.90e-02 | 1.00e+00 | 5.709 | 1 | 7 | 26 |
GO:0043234 | protein complex | 1.97e-02 | 1.00e+00 | 3.181 | 2 | 17 | 300 |
GO:0048565 | digestive tract development | 1.97e-02 | 1.00e+00 | 5.655 | 1 | 1 | 27 |
GO:0043531 | ADP binding | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 1 | 28 |
GO:0031492 | nucleosomal DNA binding | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 4 | 28 |
GO:0019894 | kinesin binding | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 1 | 28 |
GO:0001755 | neural crest cell migration | 2.18e-02 | 1.00e+00 | 5.503 | 1 | 2 | 30 |
GO:0042254 | ribosome biogenesis | 2.18e-02 | 1.00e+00 | 5.503 | 1 | 1 | 30 |
GO:0007346 | regulation of mitotic cell cycle | 2.18e-02 | 1.00e+00 | 5.503 | 1 | 3 | 30 |
GO:0019901 | protein kinase binding | 2.22e-02 | 1.00e+00 | 3.088 | 2 | 21 | 320 |
GO:0006271 | DNA strand elongation involved in DNA replication | 2.26e-02 | 1.00e+00 | 5.455 | 1 | 9 | 31 |
GO:0007093 | mitotic cell cycle checkpoint | 2.26e-02 | 1.00e+00 | 5.455 | 1 | 2 | 31 |
GO:0007411 | axon guidance | 2.31e-02 | 1.00e+00 | 3.056 | 2 | 9 | 327 |
GO:0050661 | NADP binding | 2.33e-02 | 1.00e+00 | 5.409 | 1 | 1 | 32 |
GO:0051219 | phosphoprotein binding | 2.33e-02 | 1.00e+00 | 5.409 | 1 | 3 | 32 |
GO:0033572 | transferrin transport | 2.33e-02 | 1.00e+00 | 5.409 | 1 | 6 | 32 |
GO:0031072 | heat shock protein binding | 2.40e-02 | 1.00e+00 | 5.365 | 1 | 2 | 33 |
GO:0000413 | protein peptidyl-prolyl isomerization | 2.47e-02 | 1.00e+00 | 5.322 | 1 | 1 | 34 |
GO:0003755 | peptidyl-prolyl cis-trans isomerase activity | 2.47e-02 | 1.00e+00 | 5.322 | 1 | 1 | 34 |
GO:0034332 | adherens junction organization | 2.62e-02 | 1.00e+00 | 5.240 | 1 | 1 | 36 |
GO:0051402 | neuron apoptotic process | 2.62e-02 | 1.00e+00 | 5.240 | 1 | 2 | 36 |
GO:0001895 | retina homeostasis | 2.62e-02 | 1.00e+00 | 5.240 | 1 | 1 | 36 |
GO:0030315 | T-tubule | 2.69e-02 | 1.00e+00 | 5.200 | 1 | 1 | 37 |
GO:0001102 | RNA polymerase II activating transcription factor binding | 2.69e-02 | 1.00e+00 | 5.200 | 1 | 4 | 37 |
GO:0051084 | 'de novo' posttranslational protein folding | 2.69e-02 | 1.00e+00 | 5.200 | 1 | 4 | 37 |
GO:0051539 | 4 iron, 4 sulfur cluster binding | 2.69e-02 | 1.00e+00 | 5.200 | 1 | 3 | 37 |
GO:0070527 | platelet aggregation | 2.76e-02 | 1.00e+00 | 5.162 | 1 | 2 | 38 |
GO:0050681 | androgen receptor binding | 2.76e-02 | 1.00e+00 | 5.162 | 1 | 4 | 38 |
GO:0021766 | hippocampus development | 2.83e-02 | 1.00e+00 | 5.124 | 1 | 4 | 39 |
GO:0060048 | cardiac muscle contraction | 2.83e-02 | 1.00e+00 | 5.124 | 1 | 1 | 39 |
GO:0006284 | base-excision repair | 2.83e-02 | 1.00e+00 | 5.124 | 1 | 7 | 39 |
GO:0006096 | glycolytic process | 2.83e-02 | 1.00e+00 | 5.124 | 1 | 4 | 39 |
GO:0000781 | chromosome, telomeric region | 2.90e-02 | 1.00e+00 | 5.088 | 1 | 2 | 40 |
GO:0005925 | focal adhesion | 2.91e-02 | 1.00e+00 | 2.878 | 2 | 18 | 370 |
GO:0030521 | androgen receptor signaling pathway | 2.97e-02 | 1.00e+00 | 5.052 | 1 | 2 | 41 |
GO:0035914 | skeletal muscle cell differentiation | 3.05e-02 | 1.00e+00 | 5.017 | 1 | 1 | 42 |
GO:0016020 | membrane | 3.20e-02 | 1.00e+00 | 1.640 | 4 | 80 | 1746 |
GO:0021762 | substantia nigra development | 3.33e-02 | 1.00e+00 | 4.886 | 1 | 1 | 46 |
GO:0000278 | mitotic cell cycle | 3.33e-02 | 1.00e+00 | 2.773 | 2 | 52 | 398 |
GO:0001047 | core promoter binding | 3.33e-02 | 1.00e+00 | 4.886 | 1 | 2 | 46 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 3.33e-02 | 1.00e+00 | 4.886 | 1 | 8 | 46 |
GO:0005615 | extracellular space | 3.41e-02 | 1.00e+00 | 2.014 | 3 | 17 | 1010 |
GO:0007266 | Rho protein signal transduction | 3.47e-02 | 1.00e+00 | 4.825 | 1 | 2 | 48 |
GO:0005905 | coated pit | 3.69e-02 | 1.00e+00 | 4.737 | 1 | 2 | 51 |
GO:0003684 | damaged DNA binding | 3.69e-02 | 1.00e+00 | 4.737 | 1 | 11 | 51 |
GO:0003725 | double-stranded RNA binding | 3.90e-02 | 1.00e+00 | 4.655 | 1 | 6 | 54 |
GO:0019900 | kinase binding | 3.90e-02 | 1.00e+00 | 4.655 | 1 | 1 | 54 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 3.90e-02 | 1.00e+00 | 4.655 | 1 | 5 | 54 |
GO:0050680 | negative regulation of epithelial cell proliferation | 3.90e-02 | 1.00e+00 | 4.655 | 1 | 1 | 54 |
GO:0006879 | cellular iron ion homeostasis | 4.11e-02 | 1.00e+00 | 4.577 | 1 | 5 | 57 |
GO:0000724 | double-strand break repair via homologous recombination | 4.11e-02 | 1.00e+00 | 4.577 | 1 | 6 | 57 |
GO:0008217 | regulation of blood pressure | 4.18e-02 | 1.00e+00 | 4.551 | 1 | 5 | 58 |
GO:0005654 | nucleoplasm | 4.20e-02 | 1.00e+00 | 1.898 | 3 | 83 | 1095 |
GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity | 4.25e-02 | 1.00e+00 | 4.527 | 1 | 4 | 59 |
GO:0045216 | cell-cell junction organization | 4.25e-02 | 1.00e+00 | 4.527 | 1 | 2 | 59 |
GO:0000723 | telomere maintenance | 4.25e-02 | 1.00e+00 | 4.527 | 1 | 8 | 59 |
GO:0031966 | mitochondrial membrane | 4.25e-02 | 1.00e+00 | 4.527 | 1 | 1 | 59 |
GO:0007596 | blood coagulation | 4.41e-02 | 1.00e+00 | 2.551 | 2 | 14 | 464 |
GO:0006302 | double-strand break repair | 4.47e-02 | 1.00e+00 | 4.455 | 1 | 8 | 62 |
GO:0005901 | caveola | 4.54e-02 | 1.00e+00 | 4.432 | 1 | 3 | 63 |
GO:0019903 | protein phosphatase binding | 4.54e-02 | 1.00e+00 | 4.432 | 1 | 4 | 63 |
GO:0006469 | negative regulation of protein kinase activity | 4.68e-02 | 1.00e+00 | 4.387 | 1 | 2 | 65 |
GO:0001558 | regulation of cell growth | 4.75e-02 | 1.00e+00 | 4.365 | 1 | 4 | 66 |
GO:0071260 | cellular response to mechanical stimulus | 4.75e-02 | 1.00e+00 | 4.365 | 1 | 4 | 66 |
GO:0042802 | identical protein binding | 4.88e-02 | 1.00e+00 | 2.470 | 2 | 18 | 491 |
GO:0006338 | chromatin remodeling | 4.89e-02 | 1.00e+00 | 4.322 | 1 | 4 | 68 |
GO:0006289 | nucleotide-excision repair | 4.96e-02 | 1.00e+00 | 4.301 | 1 | 12 | 69 |
GO:0003697 | single-stranded DNA binding | 4.96e-02 | 1.00e+00 | 4.301 | 1 | 9 | 69 |
GO:0042383 | sarcolemma | 5.10e-02 | 1.00e+00 | 4.260 | 1 | 3 | 71 |
GO:0034329 | cell junction assembly | 5.10e-02 | 1.00e+00 | 4.260 | 1 | 1 | 71 |
GO:0032587 | ruffle membrane | 5.17e-02 | 1.00e+00 | 4.240 | 1 | 4 | 72 |
GO:0055037 | recycling endosome | 5.24e-02 | 1.00e+00 | 4.220 | 1 | 2 | 73 |
GO:0000785 | chromatin | 5.24e-02 | 1.00e+00 | 4.220 | 1 | 5 | 73 |
GO:0055085 | transmembrane transport | 5.30e-02 | 1.00e+00 | 2.404 | 2 | 8 | 514 |
GO:0006767 | water-soluble vitamin metabolic process | 5.38e-02 | 1.00e+00 | 4.181 | 1 | 3 | 75 |
GO:0007265 | Ras protein signal transduction | 5.38e-02 | 1.00e+00 | 4.181 | 1 | 3 | 75 |
GO:0031175 | neuron projection development | 5.38e-02 | 1.00e+00 | 4.181 | 1 | 1 | 75 |
GO:0006766 | vitamin metabolic process | 5.59e-02 | 1.00e+00 | 4.124 | 1 | 3 | 78 |
GO:0071013 | catalytic step 2 spliceosome | 5.66e-02 | 1.00e+00 | 4.106 | 1 | 7 | 79 |
GO:0016032 | viral process | 5.79e-02 | 1.00e+00 | 2.333 | 2 | 55 | 540 |
GO:0002576 | platelet degranulation | 5.87e-02 | 1.00e+00 | 4.052 | 1 | 4 | 82 |
GO:0047485 | protein N-terminus binding | 6.15e-02 | 1.00e+00 | 3.983 | 1 | 4 | 86 |
GO:0006898 | receptor-mediated endocytosis | 6.15e-02 | 1.00e+00 | 3.983 | 1 | 2 | 86 |
GO:0016363 | nuclear matrix | 6.56e-02 | 1.00e+00 | 3.886 | 1 | 11 | 92 |
GO:0006928 | cellular component movement | 6.56e-02 | 1.00e+00 | 3.886 | 1 | 7 | 92 |
GO:0005200 | structural constituent of cytoskeleton | 6.63e-02 | 1.00e+00 | 3.870 | 1 | 7 | 93 |
GO:0016311 | dephosphorylation | 6.70e-02 | 1.00e+00 | 3.855 | 1 | 3 | 94 |
GO:0007010 | cytoskeleton organization | 6.84e-02 | 1.00e+00 | 3.825 | 1 | 2 | 96 |
GO:0045087 | innate immune response | 7.31e-02 | 1.00e+00 | 2.143 | 2 | 20 | 616 |
GO:0014069 | postsynaptic density | 7.52e-02 | 1.00e+00 | 3.682 | 1 | 1 | 106 |
GO:0016023 | cytoplasmic membrane-bounded vesicle | 7.59e-02 | 1.00e+00 | 3.668 | 1 | 3 | 107 |
GO:0042127 | regulation of cell proliferation | 7.87e-02 | 1.00e+00 | 3.615 | 1 | 4 | 111 |
GO:0030529 | ribonucleoprotein complex | 8.07e-02 | 1.00e+00 | 3.577 | 1 | 8 | 114 |
GO:0005819 | spindle | 8.07e-02 | 1.00e+00 | 3.577 | 1 | 7 | 114 |
GO:0006325 | chromatin organization | 8.68e-02 | 1.00e+00 | 3.467 | 1 | 4 | 123 |
GO:0006260 | DNA replication | 8.82e-02 | 1.00e+00 | 3.444 | 1 | 12 | 125 |
GO:0007050 | cell cycle arrest | 8.88e-02 | 1.00e+00 | 3.432 | 1 | 7 | 126 |
GO:0005506 | iron ion binding | 8.95e-02 | 1.00e+00 | 3.421 | 1 | 3 | 127 |
GO:0030036 | actin cytoskeleton organization | 9.09e-02 | 1.00e+00 | 3.398 | 1 | 5 | 129 |
GO:0009615 | response to virus | 9.29e-02 | 1.00e+00 | 3.365 | 1 | 6 | 132 |
GO:0000790 | nuclear chromatin | 9.36e-02 | 1.00e+00 | 3.354 | 1 | 7 | 133 |
GO:0005911 | cell-cell junction | 9.96e-02 | 1.00e+00 | 3.260 | 1 | 3 | 142 |
GO:0061024 | membrane organization | 1.02e-01 | 1.00e+00 | 3.220 | 1 | 5 | 146 |
GO:0016323 | basolateral plasma membrane | 1.04e-01 | 1.00e+00 | 3.190 | 1 | 3 | 149 |
GO:0005634 | nucleus | 1.11e-01 | 1.00e+00 | 0.757 | 6 | 131 | 4828 |
GO:0000398 | mRNA splicing, via spliceosome | 1.15e-01 | 1.00e+00 | 3.043 | 1 | 12 | 165 |
GO:0034220 | ion transmembrane transport | 1.16e-01 | 1.00e+00 | 3.026 | 1 | 2 | 167 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.17e-01 | 1.00e+00 | 3.017 | 1 | 5 | 168 |
GO:0005515 | protein binding | 1.18e-01 | 1.00e+00 | 0.636 | 7 | 172 | 6127 |
GO:0030424 | axon | 1.19e-01 | 1.00e+00 | 2.983 | 1 | 3 | 172 |
GO:0034641 | cellular nitrogen compound metabolic process | 1.23e-01 | 1.00e+00 | 2.942 | 1 | 25 | 177 |
GO:0019904 | protein domain specific binding | 1.25e-01 | 1.00e+00 | 2.910 | 1 | 6 | 181 |
GO:0009897 | external side of plasma membrane | 1.27e-01 | 1.00e+00 | 2.894 | 1 | 4 | 183 |
GO:0030168 | platelet activation | 1.41e-01 | 1.00e+00 | 2.730 | 1 | 9 | 205 |
GO:0016324 | apical plasma membrane | 1.53e-01 | 1.00e+00 | 2.602 | 1 | 2 | 224 |
GO:0003713 | transcription coactivator activity | 1.62e-01 | 1.00e+00 | 2.509 | 1 | 10 | 239 |
GO:0008134 | transcription factor binding | 1.67e-01 | 1.00e+00 | 2.467 | 1 | 8 | 246 |
GO:0005739 | mitochondrion | 1.77e-01 | 1.00e+00 | 1.379 | 2 | 24 | 1046 |
GO:0006281 | DNA repair | 1.78e-01 | 1.00e+00 | 2.365 | 1 | 22 | 264 |
GO:0000166 | nucleotide binding | 1.83e-01 | 1.00e+00 | 2.322 | 1 | 6 | 272 |
GO:0005975 | carbohydrate metabolic process | 1.84e-01 | 1.00e+00 | 2.311 | 1 | 5 | 274 |
GO:0003779 | actin binding | 1.85e-01 | 1.00e+00 | 2.306 | 1 | 7 | 275 |
GO:0044822 | poly(A) RNA binding | 1.86e-01 | 1.00e+00 | 1.335 | 2 | 50 | 1078 |
GO:0042493 | response to drug | 1.92e-01 | 1.00e+00 | 2.240 | 1 | 11 | 288 |
GO:0019899 | enzyme binding | 1.92e-01 | 1.00e+00 | 2.240 | 1 | 11 | 288 |
GO:0005856 | cytoskeleton | 2.06e-01 | 1.00e+00 | 2.129 | 1 | 8 | 311 |
GO:0043231 | intracellular membrane-bounded organelle | 2.19e-01 | 1.00e+00 | 2.034 | 1 | 8 | 332 |
GO:0003723 | RNA binding | 2.32e-01 | 1.00e+00 | 1.938 | 1 | 19 | 355 |
GO:0005524 | ATP binding | 2.62e-01 | 1.00e+00 | 1.006 | 2 | 46 | 1354 |
GO:0009986 | cell surface | 2.70e-01 | 1.00e+00 | 1.688 | 1 | 9 | 422 |
GO:0045892 | negative regulation of transcription, DNA-templated | 2.71e-01 | 1.00e+00 | 1.682 | 1 | 14 | 424 |
GO:0043066 | negative regulation of apoptotic process | 2.76e-01 | 1.00e+00 | 1.651 | 1 | 30 | 433 |
GO:0005829 | cytosol | 2.88e-01 | 1.00e+00 | 0.671 | 3 | 125 | 2562 |
GO:0006468 | protein phosphorylation | 2.94e-01 | 1.00e+00 | 1.542 | 1 | 10 | 467 |
GO:0055114 | oxidation-reduction process | 3.02e-01 | 1.00e+00 | 1.500 | 1 | 11 | 481 |
GO:0045893 | positive regulation of transcription, DNA-templated | 3.05e-01 | 1.00e+00 | 1.482 | 1 | 17 | 487 |
GO:0044267 | cellular protein metabolic process | 3.09e-01 | 1.00e+00 | 1.458 | 1 | 24 | 495 |
GO:0048471 | perinuclear region of cytoplasm | 3.24e-01 | 1.00e+00 | 1.379 | 1 | 12 | 523 |
GO:0005730 | nucleolus | 3.56e-01 | 1.00e+00 | 0.692 | 2 | 70 | 1684 |
GO:0005783 | endoplasmic reticulum | 3.67e-01 | 1.00e+00 | 1.157 | 1 | 9 | 610 |
GO:0005794 | Golgi apparatus | 3.86e-01 | 1.00e+00 | 1.065 | 1 | 14 | 650 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 4.31e-01 | 1.00e+00 | 0.863 | 1 | 11 | 748 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 4.58e-01 | 1.00e+00 | 0.746 | 1 | 19 | 811 |
GO:0005887 | integral component of plasma membrane | 5.17e-01 | 1.00e+00 | 0.501 | 1 | 7 | 961 |
GO:0005576 | extracellular region | 5.50e-01 | 1.00e+00 | 0.375 | 1 | 9 | 1049 |
GO:0006355 | regulation of transcription, DNA-templated | 5.69e-01 | 1.00e+00 | 0.301 | 1 | 17 | 1104 |
GO:0005886 | plasma membrane | 6.43e-01 | 1.00e+00 | -0.059 | 2 | 38 | 2834 |
GO:0003677 | DNA binding | 6.46e-01 | 1.00e+00 | 0.010 | 1 | 26 | 1351 |
GO:0046872 | metal ion binding | 6.77e-01 | 1.00e+00 | -0.107 | 1 | 24 | 1465 |
GO:0006351 | transcription, DNA-templated | 7.07e-01 | 1.00e+00 | -0.221 | 1 | 25 | 1585 |
GO:0005737 | cytoplasm | 8.29e-01 | 1.00e+00 | -0.548 | 2 | 98 | 3976 |
GO:0016021 | integral component of membrane | 8.62e-01 | 1.00e+00 | -0.868 | 1 | 15 | 2483 |