meta-int-snw-10454

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-56655 wolf-screen-ratio-mammosphere-adherent 0.828 9.29e-07 2.91e-03 5.53e-03 8 7
int-snw-10454 wolf-screen-ratio-mammosphere-adherent 0.950 4.20e-16 1.77e-03 3.15e-02 12 12
wolf-screen-ratio-mammosphere-adherent-meta-int-snw-10454 subnetwork

Genes (17)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
PSMA2 5683 1121.0931.106108Yes-
RBX1 9978 1151.1850.934148Yes-
PSMB7 5695 1180.9820.93490Yes-
VARS 7407 860.5491.002204Yes-
POLE4 56655 630.1770.82856--
PSMB3 5691 640.6680.90119Yes-
PGD 5226 891.2011.106152Yes-
RSL24D1 51187 381.3001.02059Yes-
RPL10 6134 20.7480.950159Yes-
RUVBL1 8607 950.7200.973469Yes-
PPP2R1A 5518 190.6440.985249Yes-
RPL14 9045 491.2501.113166Yes-
PSMB2 5690 1160.8770.956169Yes-
ACTB 60 1341.1531.151610Yes-
PSMD11 5717 1241.0951.106218Yes-
TAB1 10454 20.3380.95090Yes-
CFL1 1072 180.6741.020203Yes-

Interactions (43)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMD11 5717 RUVBL1 8607 pp -- int.I2D: YeastLow
PPP2R1A 5518 PSMB3 5691 pp -- int.I2D: IntAct_Mouse
ACTB 60 RUVBL1 8607 pp -- int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMB2 5690 POLE4 56655 pd < reg.ITFP.txt: no annot
RPL10 6134 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
PPP2R1A 5518 TAB1 10454 pp -- int.Intact: MI:0915(physical association)
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PPP2R1A 5518 RUVBL1 8607 pp -- int.I2D: YeastLow
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
ACTB 60 CFL1 1072 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, MINT_Yeast, MIPS, BioGrid, BIND_Yeast, HPRD, IntAct, IntAct_Yeast, MINT, VidalHuman_core, YeastLow, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
CFL1 1072 TAB1 10454 pp -- int.I2D: BioGrid, MINT;
int.Mint: MI:0915(physical association)
PPP2R1A 5518 PSMB2 5690 pp -- int.I2D: IntAct_Mouse
ACTB 60 PPP2R1A 5518 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 RBX1 9978 pd < reg.ITFP.txt: no annot
PGD 5226 PSMD11 5717 pp -- int.I2D: YeastLow
RUVBL1 8607 TAB1 10454 pp -- int.Intact: MI:0915(physical association);
int.I2D: MINT, IntAct;
int.Mint: MI:0915(physical association)
VARS 7407 POLE4 56655 pd <> reg.ITFP.txt: no annot
PSMA2 5683 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PPP2R1A 5518 PSMB7 5695 pp -- int.I2D: IntAct_Mouse
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 POLE4 56655 pd < reg.ITFP.txt: no annot
VARS 7407 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 POLE4 56655 pd < reg.ITFP.txt: no annot
CFL1 1072 PGD 5226 pp -- int.I2D: YeastLow
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
RPL10 6134 TAB1 10454 pp -- int.I2D: BioGrid, MINT;
int.Mint: MI:0915(physical association)
PSMB3 5691 PSMB7 5695 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS;
int.HPRD: yeast 2-hybrid
PGD 5226 PPP2R1A 5518 pp -- int.I2D: YeastLow
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
PSMB3 5691 POLE4 56655 pd < reg.ITFP.txt: no annot
RBX1 9978 TAB1 10454 pp -- int.I2D: BioGrid, MINT;
int.Mint: MI:0915(physical association)
PPP2R1A 5518 PSMA2 5683 pp -- int.I2D: IntAct_Mouse
CFL1 1072 RSL24D1 51187 pp -- int.I2D: YeastLow
PSMB2 5690 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB2 5690 VARS 7407 pd < reg.ITFP.txt: no annot
CFL1 1072 VARS 7407 pp -- int.I2D: YeastLow
PSMB3 5691 PSMD11 5717 pp -- int.I2D: YeastLow
CFL1 1072 RUVBL1 8607 pp -- int.I2D: YeastLow
PSMA2 5683 PSMB2 5690 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core

Related GO terms (239)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0016071mRNA metabolic process2.34e-113.82e-075.106834223
GO:0016070RNA metabolic process5.31e-118.67e-074.959834247
GO:0006521regulation of cellular amino acid metabolic process1.32e-092.16e-056.58552150
GO:0005839proteasome core complex2.44e-093.99e-057.73741118
GO:0000502proteasome complex2.85e-094.64e-056.37152258
GO:0004298threonine-type endopeptidase activity3.86e-096.30e-057.58541120
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle5.11e-098.34e-056.20752465
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest5.11e-098.34e-056.20752265
GO:0010467gene expression5.61e-099.15e-053.691958669
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle7.46e-091.22e-046.10052470
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent9.24e-091.51e-046.03952373
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle9.91e-091.62e-046.01952474
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.21e-081.98e-045.96252377
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.38e-082.26e-045.92552579
GO:0016032viral process2.55e-084.16e-043.830855540
GO:0002474antigen processing and presentation of peptide antigen via MHC class I3.33e-085.44e-045.67452394
GO:0005829cytosol4.36e-087.11e-042.284131252562
GO:0000209protein polyubiquitination9.61e-081.57e-035.371521116
GO:0000082G1/S transition of mitotic cell cycle3.47e-075.67e-035.000533150
GO:0042981regulation of apoptotic process3.59e-075.86e-034.991526151
GO:0034641cellular nitrogen compound metabolic process7.89e-071.29e-024.761525177
GO:0000278mitotic cell cycle2.00e-063.26e-023.855652398
GO:0043066negative regulation of apoptotic process3.25e-065.31e-023.734630433
GO:0005654nucleoplasm5.63e-069.20e-022.8108831095
GO:0070062extracellular vesicular exosome5.73e-069.35e-022.06911982516
GO:0006915apoptotic process1.59e-052.59e-013.335634571
GO:0035267NuA4 histone acetyltransferase complex9.22e-051.00e+007.1002414
GO:0016020membrane1.69e-041.00e+002.1378801746
GO:0005515protein binding2.05e-041.00e+001.133141726127
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay2.10e-041.00e+004.659310114
GO:0070262peptidyl-serine dephosphorylation1.04e-031.00e+009.907111
GO:0019521D-gluconate metabolic process1.04e-031.00e+009.907111
GO:0022625cytosolic large ribosomal subunit1.17e-031.00e+005.2922549
GO:0040008regulation of growth1.26e-031.00e+005.2352351
GO:0044281small molecule metabolic process1.42e-031.00e+002.1536571295
GO:0004832valine-tRNA ligase activity2.08e-031.00e+008.907112
GO:0019322pentose biosynthetic process2.08e-031.00e+008.907112
GO:0006438valyl-tRNA aminoacylation2.08e-031.00e+008.907112
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis2.85e-031.00e+004.6402577
GO:0005634nucleus2.85e-031.00e+001.129111314828
GO:0009051pentose-phosphate shunt, oxidative branch3.12e-031.00e+008.322113
GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity3.12e-031.00e+008.322113
GO:0019083viral transcription3.15e-031.00e+004.5672881
GO:0006415translational termination3.63e-031.00e+004.4642887
GO:0016363nuclear matrix4.05e-031.00e+004.38321192
GO:0006414translational elongation4.13e-031.00e+004.36821193
GO:0001842neural fold formation4.16e-031.00e+007.907114
GO:0031467Cul7-RING ubiquitin ligase complex4.16e-031.00e+007.907114
GO:0019788NEDD8 ligase activity4.16e-031.00e+007.907114
GO:0048273mitogen-activated protein kinase p38 binding4.16e-031.00e+007.907114
GO:0006614SRP-dependent cotranslational protein targeting to membrane5.14e-031.00e+004.20728104
GO:0031465Cul4B-RING E3 ubiquitin ligase complex5.20e-031.00e+007.585125
GO:0031461cullin-RING ubiquitin ligase complex5.20e-031.00e+007.585115
GO:0019932second-messenger-mediated signaling5.20e-031.00e+007.585115
GO:0043248proteasome assembly5.20e-031.00e+007.585115
GO:0042518negative regulation of tyrosine phosphorylation of Stat3 protein5.20e-031.00e+007.585115
GO:0030891VCB complex5.20e-031.00e+007.585125
GO:0008622epsilon DNA polymerase complex5.20e-031.00e+007.585115
GO:0015630microtubule cytoskeleton5.93e-031.00e+004.10025112
GO:0030529ribonucleoprotein complex6.14e-031.00e+004.07428114
GO:0030957Tat protein binding6.23e-031.00e+007.322146
GO:0019209kinase activator activity6.23e-031.00e+007.322116
GO:0031466Cul5-RING ubiquitin ligase complex6.23e-031.00e+007.322116
GO:0019058viral life cycle6.25e-031.00e+004.061210115
GO:0006325chromatin organization7.12e-031.00e+003.96424123
GO:0030836positive regulation of actin filament depolymerization7.27e-031.00e+007.100127
GO:0002161aminoacyl-tRNA editing activity7.27e-031.00e+007.100127
GO:0031462Cul2-RING ubiquitin ligase complex7.27e-031.00e+007.100127
GO:0006413translational initiation8.04e-031.00e+003.874212131
GO:0009615response to virus8.15e-031.00e+003.86326132
GO:0019773proteasome core complex, alpha-subunit complex8.30e-031.00e+006.907158
GO:0031464Cul4A-RING E3 ubiquitin ligase complex8.30e-031.00e+006.907128
GO:0070688MLL5-L complex8.30e-031.00e+006.907118
GO:0030042actin filament depolymerization8.30e-031.00e+006.907128
GO:0000812Swr1 complex8.30e-031.00e+006.907138
GO:0045116protein neddylation8.30e-031.00e+006.907128
GO:0003735structural constituent of ribosome9.26e-031.00e+003.76728141
GO:0000185activation of MAPKKK activity9.34e-031.00e+006.737129
GO:0006450regulation of translational fidelity1.04e-021.00e+006.5851210
GO:0007084mitotic nuclear envelope reassembly1.04e-021.00e+006.5851110
GO:0006098pentose-phosphate shunt1.14e-021.00e+006.4481311
GO:0061001regulation of dendritic spine morphogenesis1.14e-021.00e+006.4481211
GO:0006275regulation of DNA replication1.24e-021.00e+006.3221212
GO:0030111regulation of Wnt signaling pathway1.24e-021.00e+006.3221112
GO:0043968histone H2A acetylation1.24e-021.00e+006.3221312
GO:0005838proteasome regulatory particle1.24e-021.00e+006.3221712
GO:0042273ribosomal large subunit biogenesis1.35e-021.00e+006.2071413
GO:0044267cellular protein metabolic process1.37e-021.00e+002.541324495
GO:0031011Ino80 complex1.45e-021.00e+006.1001314
GO:0006672ceramide metabolic process1.55e-021.00e+006.0001115
GO:0005671Ada2/Gcn5/Ada3 transcription activator complex1.55e-021.00e+006.0001115
GO:2001241positive regulation of extrinsic apoptotic signaling pathway in absence of ligand1.55e-021.00e+006.0001215
GO:0032403protein complex binding1.55e-021.00e+003.37627185
GO:0050998nitric-oxide synthase binding1.65e-021.00e+005.9071116
GO:0010243response to organonitrogen compound1.76e-021.00e+005.8201217
GO:0022624proteasome accessory complex1.76e-021.00e+005.8201917
GO:0031258lamellipodium membrane1.76e-021.00e+005.8201217
GO:0022604regulation of cell morphogenesis1.76e-021.00e+005.8201117
GO:0003678DNA helicase activity1.96e-021.00e+005.6591319
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process1.96e-021.00e+005.6591119
GO:0048863stem cell differentiation1.96e-021.00e+005.6591119
GO:0008601protein phosphatase type 2A regulator activity2.06e-021.00e+005.5851320
GO:0000159protein phosphatase type 2A complex2.06e-021.00e+005.5851220
GO:0030010establishment of cell polarity2.17e-021.00e+005.5151221
GO:0045595regulation of cell differentiation2.17e-021.00e+005.5151121
GO:0000281mitotic cytokinesis2.17e-021.00e+005.5151221
GO:0030863cortical cytoskeleton2.27e-021.00e+005.4481122
GO:0036464cytoplasmic ribonucleoprotein granule2.27e-021.00e+005.4481422
GO:0043044ATP-dependent chromatin remodeling2.37e-021.00e+005.3831423
GO:0031463Cul3-RING ubiquitin ligase complex2.37e-021.00e+005.3831223
GO:0043200response to amino acid2.37e-021.00e+005.3831123
GO:0006513protein monoubiquitination2.37e-021.00e+005.3831123
GO:0006412translation2.44e-021.00e+003.030215235
GO:0045087innate immune response2.45e-021.00e+002.225320616
GO:0005730nucleolus2.50e-021.00e+001.5115701684
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway2.57e-021.00e+005.2631225
GO:0030864cortical actin cytoskeleton2.57e-021.00e+005.2631125
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia2.68e-021.00e+005.2071226
GO:0034080CENP-A containing nucleosome assembly2.78e-021.00e+005.1521227
GO:0000188inactivation of MAPK activity2.78e-021.00e+005.1521127
GO:0071339MLL1 complex2.78e-021.00e+005.1521327
GO:0003823antigen binding2.88e-021.00e+005.1001128
GO:0010033response to organic substance2.88e-021.00e+005.1001228
GO:0043967histone H4 acetylation2.88e-021.00e+005.1001328
GO:0031492nucleosomal DNA binding2.88e-021.00e+005.1001428
GO:0019894kinesin binding2.88e-021.00e+005.1001128
GO:0019005SCF ubiquitin ligase complex2.98e-021.00e+005.0491129
GO:0003887DNA-directed DNA polymerase activity2.98e-021.00e+005.0491329
GO:0071897DNA biosynthetic process2.98e-021.00e+005.0491229
GO:0006281DNA repair3.02e-021.00e+002.863222264
GO:0001755neural crest cell migration3.08e-021.00e+005.0001230
GO:0042254ribosome biogenesis3.08e-021.00e+005.0001130
GO:0050661NADP binding3.28e-021.00e+004.9071132
GO:0003007heart morphogenesis3.48e-021.00e+004.8201134
GO:0034332adherens junction organization3.69e-021.00e+004.7371136
GO:0001895retina homeostasis3.69e-021.00e+004.7371136
GO:0051084'de novo' posttranslational protein folding3.79e-021.00e+004.6981437
GO:0043234protein complex3.82e-021.00e+002.678217300
GO:0070527platelet aggregation3.89e-021.00e+004.6591238
GO:0008047enzyme activator activity3.99e-021.00e+004.6221139
GO:0007249I-kappaB kinase/NF-kappaB signaling4.19e-021.00e+004.5491141
GO:0006418tRNA aminoacylation for protein translation4.29e-021.00e+004.5151542
GO:0004722protein serine/threonine phosphatase activity4.29e-021.00e+004.5151142
GO:0030155regulation of cell adhesion4.29e-021.00e+004.5151342
GO:0032508DNA duplex unwinding4.29e-021.00e+004.5151442
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway4.39e-021.00e+004.4811243
GO:0014070response to organic cyclic compound4.39e-021.00e+004.4811343
GO:0007411axon guidance4.46e-021.00e+002.55429327
GO:0043966histone H3 acetylation4.59e-021.00e+004.4151245
GO:0021762substantia nigra development4.69e-021.00e+004.3831146
GO:0007266Rho protein signal transduction4.89e-021.00e+004.3221248
GO:0007254JNK cascade5.18e-021.00e+004.2351251
GO:0000775chromosome, centromeric region5.28e-021.00e+004.2071252
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding5.48e-021.00e+004.1521554
GO:0051403stress-activated MAPK cascade5.48e-021.00e+004.1521154
GO:0005925focal adhesion5.57e-021.00e+002.376218370
GO:0003824catalytic activity5.68e-021.00e+004.1001156
GO:0000932cytoplasmic mRNA processing body5.68e-021.00e+004.1001356
GO:0045216cell-cell junction organization5.97e-021.00e+004.0241259
GO:0046982protein heterodimerization activity6.37e-021.00e+002.267211399
GO:0007059chromosome segregation6.46e-021.00e+003.9071364
GO:0034146toll-like receptor 5 signaling pathway6.56e-021.00e+003.8851165
GO:0034166toll-like receptor 10 signaling pathway6.56e-021.00e+003.8851165
GO:0006310DNA recombination6.76e-021.00e+003.8411467
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway7.15e-021.00e+003.7571171
GO:0034329cell junction assembly7.15e-021.00e+003.7571171
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway7.15e-021.00e+003.7571171
GO:0032587ruffle membrane7.24e-021.00e+003.7371472
GO:0034162toll-like receptor 9 signaling pathway7.24e-021.00e+003.7371172
GO:0034134toll-like receptor 2 signaling pathway7.34e-021.00e+003.7171173
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process7.63e-021.00e+003.6591376
GO:0030324lung development7.63e-021.00e+003.6591176
GO:0035666TRIF-dependent toll-like receptor signaling pathway7.63e-021.00e+003.6591276
GO:0002756MyD88-independent toll-like receptor signaling pathway7.82e-021.00e+003.6221278
GO:0006334nucleosome assembly7.92e-021.00e+003.6031479
GO:0002755MyD88-dependent toll-like receptor signaling pathway8.02e-021.00e+003.5851280
GO:0034138toll-like receptor 3 signaling pathway8.02e-021.00e+003.5851280
GO:0002576platelet degranulation8.21e-021.00e+003.5491482
GO:0007596blood coagulation8.28e-021.00e+002.049214464
GO:0000187activation of MAPK activity8.98e-021.00e+003.4151490
GO:0005739mitochondrion9.12e-021.00e+001.4613241046
GO:0006928cellular component movement9.17e-021.00e+003.3831792
GO:0005200structural constituent of cytoskeleton9.26e-021.00e+003.3681793
GO:0006364rRNA processing9.55e-021.00e+003.3221596
GO:0007010cytoskeleton organization9.55e-021.00e+003.3221296
GO:0034142toll-like receptor 4 signaling pathway9.55e-021.00e+003.3221296
GO:0071456cellular response to hypoxia9.74e-021.00e+003.2921498
GO:0006470protein dephosphorylation9.83e-021.00e+003.2781199
GO:0014069postsynaptic density1.05e-011.00e+003.17911106
GO:0002224toll-like receptor signaling pathway1.08e-011.00e+003.13912109
GO:0005815microtubule organizing center1.09e-011.00e+003.12614110
GO:0006461protein complex assembly1.10e-011.00e+003.11316111
GO:0030308negative regulation of cell growth1.11e-011.00e+003.08716113
GO:0072562blood microparticle1.14e-011.00e+003.04914116
GO:0007219Notch signaling pathway1.23e-011.00e+002.94114125
GO:0051092positive regulation of NF-kappaB transcription factor activity1.23e-011.00e+002.94114125
GO:0006511ubiquitin-dependent protein catabolic process1.24e-011.00e+002.91815127
GO:0030036actin cytoskeleton organization1.26e-011.00e+002.89615129
GO:0007179transforming growth factor beta receptor signaling pathway1.27e-011.00e+002.88513130
GO:0000790nuclear chromatin1.30e-011.00e+002.85217133
GO:0031982vesicle1.31e-011.00e+002.841110134
GO:0000086G2/M transition of mitotic cell cycle1.34e-011.00e+002.80917137
GO:0005911cell-cell junction1.38e-011.00e+002.75713142
GO:0016887ATPase activity1.40e-011.00e+002.73717144
GO:0061024membrane organization1.42e-011.00e+002.71715146
GO:0006457protein folding1.44e-011.00e+002.68818149
GO:0005794Golgi apparatus1.45e-011.00e+001.563214650
GO:0010008endosome membrane1.52e-011.00e+002.61216157
GO:0008543fibroblast growth factor receptor signaling pathway1.53e-011.00e+002.59414159
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding1.61e-011.00e+002.51515168
GO:0005524ATP binding1.62e-011.00e+001.0893461354
GO:0038095Fc-epsilon receptor signaling pathway1.64e-011.00e+002.48917171
GO:0030424axon1.65e-011.00e+002.48113172
GO:0031625ubiquitin protein ligase binding1.72e-011.00e+002.415113180
GO:0015629actin cytoskeleton1.75e-011.00e+002.39115183
GO:0030168platelet activation1.93e-011.00e+002.22719205
GO:0001701in utero embryonic development1.98e-011.00e+002.19316210
GO:0005737cytoplasm2.15e-011.00e+000.5356983976
GO:0007067mitotic nuclear division2.15e-011.00e+002.055113231
GO:0008380RNA splicing2.16e-011.00e+002.049113232
GO:0004842ubiquitin-protein transferase activity2.36e-011.00e+001.90714256
GO:0005975carbohydrate metabolic process2.50e-011.00e+001.80915274
GO:0003779actin binding2.51e-011.00e+001.80417275
GO:0006357regulation of transcription from RNA polymerase II promoter2.51e-011.00e+001.80416275
GO:0007283spermatogenesis2.52e-011.00e+001.79816276
GO:0016567protein ubiquitination2.70e-011.00e+001.68315299
GO:0005856cytoskeleton2.79e-011.00e+001.62618311
GO:0005615extracellular space2.84e-011.00e+000.9272171010
GO:0019901protein kinase binding2.86e-011.00e+001.585121320
GO:0043231intracellular membrane-bounded organelle2.95e-011.00e+001.53218332
GO:0044822poly(A) RNA binding3.11e-011.00e+000.8332501078
GO:0003723RNA binding3.12e-011.00e+001.435119355
GO:0043565sequence-specific DNA binding3.19e-011.00e+001.39514365
GO:0006468protein phosphorylation3.90e-011.00e+001.040110467
GO:0055114oxidation-reduction process3.99e-011.00e+000.997111481
GO:0005783endoplasmic reticulum4.77e-011.00e+000.65419610
GO:0008270zinc ion binding6.83e-011.00e+00-0.1521121067
GO:0006355regulation of transcription, DNA-templated6.96e-011.00e+00-0.2021171104
GO:0006351transcription, DNA-templated8.24e-011.00e+00-0.7231251585