int-snw-8886

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.961	1.59e-16	1.39e-03	2.64e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-8886 subnetwork

Genes (10)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
RSL24D1	51187	36	1.300	1.020	59	Yes	-
ACO2	50	50	1.000	1.076	191	Yes	-
EEF2	1938	27	0.890	1.043	301	Yes	-
[ DDX18 ]	8886	9	0.660	1.013	173	Yes	-
RPS11	6205	36	0.993	1.113	175	Yes	-
RPL8	6132	9	0.778	0.967	218	Yes	-
RPL6	6128	11	0.844	1.113	164	Yes	-
PSMD11	5717	121	1.095	1.106	183	Yes	-
OGDH	4967	13	0.847	1.076	113	Yes	-
PGD	5226	75	1.201	1.106	138	Yes	-

Interactions (21)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ACO2	50	DDX18	8886	pp	--	int.I2D: YeastLow
EEF2	1938	PGD	5226	pp	--	int.I2D: BioGrid_Yeast
RPL6	6128	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
PGD	5226	DDX18	8886	pp	--	int.I2D: YeastLow
PSMD11	5717	DDX18	8886	pp	--	int.I2D: YeastLow
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
RPL8	6132	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
RPL8	6132	DDX18	8886	pp	--	int.I2D: BioGrid_Yeast
OGDH	4967	RPL6	6128	pp	--	int.I2D: IntAct_Yeast
RPS11	6205	DDX18	8886	pp	--	int.I2D: BioGrid_Yeast
OGDH	4967	RPL8	6132	pp	--	int.I2D: IntAct_Yeast
DDX18	8886	RSL24D1	51187	pp	--	int.I2D: YeastLow, BioGrid_Yeast
OGDH	4967	PGD	5226	pp	--	int.I2D: YeastLow
EEF2	1938	DDX18	8886	pp	--	int.I2D: YeastLow
ACO2	50	OGDH	4967	pp	--	int.I2D: YeastLow
ACO2	50	PSMD11	5717	pp	--	int.I2D: YeastLow
RPL6	6128	DDX18	8886	pp	--	int.I2D: BioGrid_Yeast
OGDH	4967	PSMD11	5717	pp	--	int.I2D: YeastLow
ACO2	50	PGD	5226	pp	--	int.I2D: YeastLow
RPL6	6128	RPL8	6132	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
OGDH	4967	DDX18	8886	pp	--	int.I2D: YeastLow

Related GO terms (109)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006414	translational elongation	3.30e-07	4.76e-03	5.955	4	13	93
GO:0016071	mRNA metabolic process	1.09e-05	1.57e-01	4.693	4	31	223
GO:0006412	translation	1.23e-05	1.77e-01	4.649	4	20	230
GO:0016070	RNA metabolic process	1.63e-05	2.34e-01	4.546	4	32	247
GO:0019083	viral transcription	1.99e-05	2.87e-01	5.739	3	10	81
GO:0006415	translational termination	2.47e-05	3.56e-01	5.636	3	10	87
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	4.21e-05	6.08e-01	5.379	3	10	104
GO:0010467	gene expression	4.39e-05	6.33e-01	3.430	5	59	669
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	5.54e-05	7.99e-01	5.246	3	11	114
GO:0019058	viral life cycle	5.69e-05	8.21e-01	5.234	3	13	115
GO:0006413	translational initiation	8.39e-05	1.00e+00	5.046	3	17	131
GO:0003735	structural constituent of ribosome	9.58e-05	1.00e+00	4.981	3	10	137
GO:0019843	rRNA binding	1.50e-04	1.00e+00	6.739	2	3	27
GO:0006099	tricarboxylic acid cycle	1.62e-04	1.00e+00	6.687	2	4	28
GO:0044267	cellular protein metabolic process	2.07e-04	1.00e+00	3.605	4	29	474
GO:0016032	viral process	3.27e-04	1.00e+00	3.433	4	55	534
GO:0016020	membrane	3.44e-04	1.00e+00	2.364	6	90	1681
GO:0044822	poly(A) RNA binding	3.85e-04	1.00e+00	2.772	5	49	1056
GO:0022625	cytosolic large ribosomal subunit	5.00e-04	1.00e+00	5.879	2	6	49
GO:0006091	generation of precursor metabolites and energy	5.21e-04	1.00e+00	5.850	2	3	50
GO:0019521	D-gluconate metabolic process	6.93e-04	1.00e+00	10.494	1	1	1
GO:0034602	oxoglutarate dehydrogenase (NAD+) activity	6.93e-04	1.00e+00	10.494	1	1	1
GO:0019322	pentose biosynthetic process	1.39e-03	1.00e+00	9.494	1	2	2
GO:0003994	aconitate hydratase activity	1.39e-03	1.00e+00	9.494	1	1	2
GO:0061034	olfactory bulb mitral cell layer development	1.39e-03	1.00e+00	9.494	1	1	2
GO:0045252	oxoglutarate dehydrogenase complex	1.39e-03	1.00e+00	9.494	1	2	2
GO:0051538	3 iron, 4 sulfur cluster binding	1.39e-03	1.00e+00	9.494	1	1	2
GO:0005925	focal adhesion	1.70e-03	1.00e+00	3.563	3	19	366
GO:0009051	pentose-phosphate shunt, oxidative branch	2.08e-03	1.00e+00	8.909	1	2	3
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	2.08e-03	1.00e+00	8.909	1	1	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	2.08e-03	1.00e+00	8.909	1	1	3
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	2.08e-03	1.00e+00	8.909	1	1	3
GO:0006734	NADH metabolic process	2.77e-03	1.00e+00	8.494	1	1	4
GO:0006104	succinyl-CoA metabolic process	2.77e-03	1.00e+00	8.494	1	1	4
GO:0044237	cellular metabolic process	2.81e-03	1.00e+00	4.624	2	5	117
GO:0005829	cytosol	2.97e-03	1.00e+00	1.794	6	132	2496
GO:0043248	proteasome assembly	3.46e-03	1.00e+00	8.172	1	1	5
GO:0006102	isocitrate metabolic process	3.46e-03	1.00e+00	8.172	1	1	5
GO:0030976	thiamine pyrophosphate binding	3.46e-03	1.00e+00	8.172	1	1	5
GO:0006101	citrate metabolic process	4.15e-03	1.00e+00	7.909	1	1	6
GO:0021860	pyramidal neuron development	4.15e-03	1.00e+00	7.909	1	1	6
GO:0021695	cerebellar cortex development	4.15e-03	1.00e+00	7.909	1	2	6
GO:0006554	lysine catabolic process	5.53e-03	1.00e+00	7.494	1	2	8
GO:0034641	cellular nitrogen compound metabolic process	5.91e-03	1.00e+00	4.076	2	20	171
GO:0008494	translation activator activity	6.22e-03	1.00e+00	7.324	1	1	9
GO:0044281	small molecule metabolic process	6.88e-03	1.00e+00	2.252	4	58	1211
GO:0006098	pentose-phosphate shunt	6.91e-03	1.00e+00	7.172	1	4	10
GO:0021756	striatum development	6.91e-03	1.00e+00	7.172	1	1	10
GO:0021794	thalamus development	7.60e-03	1.00e+00	7.035	1	1	11
GO:0005838	proteasome regulatory particle	8.29e-03	1.00e+00	6.909	1	7	12
GO:0005759	mitochondrial matrix	1.03e-02	1.00e+00	3.661	2	14	228
GO:0006103	2-oxoglutarate metabolic process	1.10e-02	1.00e+00	6.494	1	1	16
GO:0003746	translation elongation factor activity	1.17e-02	1.00e+00	6.407	1	3	17
GO:0022624	proteasome accessory complex	1.17e-02	1.00e+00	6.407	1	8	17
GO:0004004	ATP-dependent RNA helicase activity	1.24e-02	1.00e+00	6.324	1	2	18
GO:0048863	stem cell differentiation	1.31e-02	1.00e+00	6.246	1	1	19
GO:0036464	cytoplasmic ribonucleoprotein granule	1.52e-02	1.00e+00	6.035	1	4	22
GO:0005844	polysome	1.58e-02	1.00e+00	5.971	1	4	23
GO:0050661	NADP binding	1.86e-02	1.00e+00	5.739	1	2	27
GO:0042254	ribosome biogenesis	2.06e-02	1.00e+00	5.587	1	1	30
GO:0003723	RNA binding	2.22e-02	1.00e+00	3.076	2	20	342
GO:0031072	heat shock protein binding	2.27e-02	1.00e+00	5.450	1	1	33
GO:0051539	4 iron, 4 sulfur cluster binding	2.40e-02	1.00e+00	5.365	1	3	35
GO:0021766	hippocampus development	2.60e-02	1.00e+00	5.246	1	4	38
GO:0006096	glycolytic process	2.60e-02	1.00e+00	5.246	1	4	38
GO:0022627	cytosolic small ribosomal subunit	2.67e-02	1.00e+00	5.209	1	4	39
GO:0045727	positive regulation of translation	3.01e-02	1.00e+00	5.035	1	3	44
GO:0006521	regulation of cellular amino acid metabolic process	3.41e-02	1.00e+00	4.850	1	17	50
GO:0002244	hematopoietic progenitor cell differentiation	3.68e-02	1.00e+00	4.739	1	1	54
GO:0031966	mitochondrial membrane	3.75e-02	1.00e+00	4.713	1	1	55
GO:0005840	ribosome	3.95e-02	1.00e+00	4.636	1	1	58
GO:0000502	proteasome complex	3.95e-02	1.00e+00	4.636	1	17	58
GO:0051087	chaperone binding	4.02e-02	1.00e+00	4.612	1	6	59
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	4.35e-02	1.00e+00	4.494	1	19	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.42e-02	1.00e+00	4.472	1	22	65
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.75e-02	1.00e+00	4.365	1	22	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	4.88e-02	1.00e+00	4.324	1	20	72
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.02e-02	1.00e+00	4.285	1	22	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	5.08e-02	1.00e+00	4.265	1	20	75
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	5.35e-02	1.00e+00	4.190	1	23	79
GO:0001649	osteoblast differentiation	6.20e-02	1.00e+00	3.971	1	6	92
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	6.20e-02	1.00e+00	3.971	1	21	92
GO:0070062	extracellular vesicular exosome	6.93e-02	1.00e+00	1.265	4	104	2400
GO:0005506	iron ion binding	7.05e-02	1.00e+00	3.780	1	4	105
GO:0030529	ribonucleoprotein complex	7.50e-02	1.00e+00	3.687	1	8	112
GO:0000209	protein polyubiquitination	7.76e-02	1.00e+00	3.636	1	20	116
GO:0006511	ubiquitin-dependent protein catabolic process	8.40e-02	1.00e+00	3.517	1	5	126
GO:0010628	positive regulation of gene expression	9.68e-02	1.00e+00	3.304	1	5	146
GO:0000082	G1/S transition of mitotic cell cycle	9.87e-02	1.00e+00	3.275	1	32	149
GO:0042981	regulation of apoptotic process	9.93e-02	1.00e+00	3.265	1	24	150
GO:0003924	GTPase activity	1.29e-01	1.00e+00	2.872	1	12	197
GO:0006184	GTP catabolic process	1.39e-01	1.00e+00	2.753	1	12	214
GO:0005739	mitochondrion	1.49e-01	1.00e+00	1.531	2	28	998
GO:0005975	carbohydrate metabolic process	1.62e-01	1.00e+00	2.511	1	9	253
GO:0005634	nucleus	1.79e-01	1.00e+00	0.662	5	136	4559
GO:0006200	ATP catabolic process	1.85e-01	1.00e+00	2.304	1	15	292
GO:0005525	GTP binding	1.95e-01	1.00e+00	2.218	1	12	310
GO:0019901	protein kinase binding	1.99e-01	1.00e+00	2.186	1	21	317
GO:0000278	mitotic cell cycle	2.40e-01	1.00e+00	1.883	1	48	391
GO:0055114	oxidation-reduction process	2.56e-01	1.00e+00	1.780	1	12	420
GO:0043066	negative regulation of apoptotic process	2.58e-01	1.00e+00	1.766	1	31	424
GO:0005730	nucleolus	3.18e-01	1.00e+00	0.814	2	69	1641
GO:0006915	apoptotic process	3.25e-01	1.00e+00	1.378	1	33	555
GO:0006355	regulation of transcription, DNA-templated	5.12e-01	1.00e+00	0.533	1	18	997
GO:0005654	nucleoplasm	5.42e-01	1.00e+00	0.415	1	76	1082
GO:0003677	DNA binding	5.86e-01	1.00e+00	0.244	1	28	1218
GO:0005524	ATP binding	6.11e-01	1.00e+00	0.152	1	60	1298
GO:0046872	metal ion binding	6.13e-01	1.00e+00	0.142	1	25	1307
GO:0005515	protein binding	6.61e-01	1.00e+00	-0.062	4	184	6024

Wolf-ratios-Mammosphere-Adherent

int-snw-8886

Statistics

Genes (10)

Interactions (21)

Related GO terms (109)