int-snw-8507

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	1.014	1.02e-18	3.91e-04	1.01e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-8507 subnetwork

Genes (6)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
ACTB	60	167	1.153	1.151	587	Yes	-
[ ENC1 ]	8507	1	0.211	1.014	11	Yes	-
CSNK1A1	1452	2	0.396	1.014	156	Yes	-
RBX1	9978	97	1.185	1.151	139	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-
HNRNPC	3183	20	1.812	1.026	119	Yes	-

Interactions (6)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ACTB	60	RBX1	9978	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	CSNK1A1	1452	pp	--	int.I2D: HPRD, BCI; int.HPRD: in vitro
ENC1	8507	RBX1	9978	pp	--	int.I2D: BioGrid
CSNK1A1	1452	ENC1	8507	pp	--	int.I2D: Miller_WntLumier
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
CSNK1A1	1452	HNRNPC	3183	pp	--	int.I2D: BCI; int.HPRD: in vitro

Related GO terms (124)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0043044	ATP-dependent chromatin remodeling	3.63e-05	5.24e-01	7.708	2	4	23
GO:0031463	Cul3-RING ubiquitin ligase complex	3.63e-05	5.24e-01	7.708	2	3	23
GO:0031492	nucleosomal DNA binding	5.04e-05	7.27e-01	7.476	2	4	27
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	1.97e-04	1.00e+00	6.503	2	5	53
GO:0005829	cytosol	7.95e-04	1.00e+00	2.268	5	132	2496
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	8.32e-04	1.00e+00	10.231	1	1	2
GO:0005055	laminin receptor activity	8.32e-04	1.00e+00	10.231	1	1	2
GO:0006407	rRNA export from nucleus	8.32e-04	1.00e+00	10.231	1	1	2
GO:0000790	nuclear chromatin	1.16e-03	1.00e+00	5.220	2	9	129
GO:0019788	NEDD8 ligase activity	1.66e-03	1.00e+00	9.231	1	1	4
GO:0010499	proteasomal ubiquitin-independent protein catabolic process	1.66e-03	1.00e+00	9.231	1	2	4
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.66e-03	1.00e+00	9.231	1	1	4
GO:0030686	90S preribosome	1.66e-03	1.00e+00	9.231	1	1	4
GO:0031467	Cul7-RING ubiquitin ligase complex	1.66e-03	1.00e+00	9.231	1	1	4
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.89e-03	1.00e+00	4.865	2	7	165
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	2.08e-03	1.00e+00	8.909	1	3	5
GO:0031461	cullin-RING ubiquitin ligase complex	2.08e-03	1.00e+00	8.909	1	1	5
GO:0030891	VCB complex	2.08e-03	1.00e+00	8.909	1	2	5
GO:0016020	membrane	2.27e-03	1.00e+00	2.516	4	90	1681
GO:0030957	Tat protein binding	2.49e-03	1.00e+00	8.646	1	3	6
GO:0031466	Cul5-RING ubiquitin ligase complex	2.49e-03	1.00e+00	8.646	1	1	6
GO:0000028	ribosomal small subunit assembly	2.91e-03	1.00e+00	8.424	1	1	7
GO:0031462	Cul2-RING ubiquitin ligase complex	2.91e-03	1.00e+00	8.424	1	2	7
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	3.32e-03	1.00e+00	8.231	1	2	8
GO:0070688	MLL5-L complex	3.32e-03	1.00e+00	8.231	1	1	8
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	3.32e-03	1.00e+00	8.231	1	1	8
GO:0045116	protein neddylation	3.32e-03	1.00e+00	8.231	1	2	8
GO:0045120	pronucleus	4.57e-03	1.00e+00	7.772	1	2	11
GO:0070935	3'-UTR-mediated mRNA stabilization	4.98e-03	1.00e+00	7.646	1	2	12
GO:0005515	protein binding	5.30e-03	1.00e+00	1.260	6	184	6024
GO:0008266	poly(U) RNA binding	5.40e-03	1.00e+00	7.531	1	1	13
GO:0005856	cytoskeleton	5.77e-03	1.00e+00	4.046	2	12	291
GO:0035267	NuA4 histone acetyltransferase complex	5.81e-03	1.00e+00	7.424	1	4	14
GO:0043234	protein complex	5.92e-03	1.00e+00	4.027	2	18	295
GO:0016567	protein ubiquitination	5.92e-03	1.00e+00	4.027	2	5	295
GO:0050998	nitric-oxide synthase binding	6.64e-03	1.00e+00	7.231	1	1	16
GO:0005654	nucleoplasm	7.09e-03	1.00e+00	2.737	3	76	1082
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	7.88e-03	1.00e+00	6.983	1	1	19
GO:0030863	cortical cytoskeleton	9.12e-03	1.00e+00	6.772	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	9.12e-03	1.00e+00	6.772	1	4	22
GO:0006513	protein monoubiquitination	9.53e-03	1.00e+00	6.708	1	1	23
GO:0043236	laminin binding	9.53e-03	1.00e+00	6.708	1	1	23
GO:0003730	mRNA 3'-UTR binding	1.08e-02	1.00e+00	6.531	1	2	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	1.08e-02	1.00e+00	6.531	1	3	26
GO:0043022	ribosome binding	1.12e-02	1.00e+00	6.476	1	3	27
GO:0019894	kinesin binding	1.16e-02	1.00e+00	6.424	1	1	28
GO:0019005	SCF ubiquitin ligase complex	1.20e-02	1.00e+00	6.373	1	1	29
GO:0001895	retina homeostasis	1.41e-02	1.00e+00	6.144	1	1	34
GO:0044267	cellular protein metabolic process	1.48e-02	1.00e+00	3.342	2	29	474
GO:0034332	adherens junction organization	1.49e-02	1.00e+00	6.061	1	1	36
GO:0051084	'de novo' posttranslational protein folding	1.53e-02	1.00e+00	6.022	1	4	37
GO:0070527	platelet aggregation	1.57e-02	1.00e+00	5.983	1	2	38
GO:0022627	cytosolic small ribosomal subunit	1.61e-02	1.00e+00	5.946	1	4	39
GO:0017148	negative regulation of translation	1.65e-02	1.00e+00	5.909	1	2	40
GO:0021762	substantia nigra development	1.82e-02	1.00e+00	5.772	1	2	44
GO:0016032	viral process	1.86e-02	1.00e+00	3.170	2	55	534
GO:0045216	cell-cell junction organization	2.23e-02	1.00e+00	5.476	1	2	54
GO:0034329	cell junction assembly	2.80e-02	1.00e+00	5.144	1	1	68
GO:0000777	condensed chromosome kinetochore	2.80e-02	1.00e+00	5.144	1	4	68
GO:0010467	gene expression	2.85e-02	1.00e+00	2.845	2	59	669
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	3.04e-02	1.00e+00	5.022	1	6	74
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	3.08e-02	1.00e+00	5.002	1	2	75
GO:0071013	catalytic step 2 spliceosome	3.20e-02	1.00e+00	4.946	1	4	78
GO:0019083	viral transcription	3.32e-02	1.00e+00	4.891	1	10	81
GO:0005681	spliceosomal complex	3.40e-02	1.00e+00	4.856	1	4	83
GO:0006415	translational termination	3.57e-02	1.00e+00	4.788	1	10	87
GO:0005200	structural constituent of cytoskeleton	3.73e-02	1.00e+00	4.723	1	8	91
GO:0016363	nuclear matrix	3.73e-02	1.00e+00	4.723	1	12	91
GO:0006928	cellular component movement	3.73e-02	1.00e+00	4.723	1	7	91
GO:0001649	osteoblast differentiation	3.77e-02	1.00e+00	4.708	1	6	92
GO:0071456	cellular response to hypoxia	3.77e-02	1.00e+00	4.708	1	6	92
GO:0006414	translational elongation	3.81e-02	1.00e+00	4.692	1	13	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	4.25e-02	1.00e+00	4.531	1	10	104
GO:0014069	postsynaptic density	4.29e-02	1.00e+00	4.517	1	3	105
GO:0072562	blood microparticle	4.53e-02	1.00e+00	4.437	1	3	111
GO:0030529	ribonucleoprotein complex	4.57e-02	1.00e+00	4.424	1	8	112
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	4.65e-02	1.00e+00	4.398	1	11	114
GO:0019058	viral life cycle	4.69e-02	1.00e+00	4.386	1	13	115
GO:0006325	chromatin organization	4.81e-02	1.00e+00	4.348	1	5	118
GO:0007219	Notch signaling pathway	4.89e-02	1.00e+00	4.324	1	5	120
GO:0006413	translational initiation	5.33e-02	1.00e+00	4.198	1	17	131
GO:0003735	structural constituent of ribosome	5.57e-02	1.00e+00	4.133	1	10	137
GO:0016055	Wnt signaling pathway	5.61e-02	1.00e+00	4.123	1	7	138
GO:0006457	protein folding	5.80e-02	1.00e+00	4.071	1	7	143
GO:0061024	membrane organization	5.88e-02	1.00e+00	4.051	1	7	145
GO:0007166	cell surface receptor signaling pathway	5.96e-02	1.00e+00	4.031	1	3	147
GO:0070062	extracellular vesicular exosome	6.20e-02	1.00e+00	1.587	3	104	2400
GO:0044822	poly(A) RNA binding	6.59e-02	1.00e+00	2.187	2	49	1056
GO:0000398	mRNA splicing, via spliceosome	6.63e-02	1.00e+00	3.874	1	8	164
GO:0030424	axon	6.71e-02	1.00e+00	3.856	1	4	166
GO:0016607	nuclear speck	6.95e-02	1.00e+00	3.805	1	3	172
GO:0004672	protein kinase activity	7.14e-02	1.00e+00	3.764	1	6	177
GO:0031625	ubiquitin protein ligase binding	7.18e-02	1.00e+00	3.755	1	14	178
GO:0032403	protein complex binding	7.38e-02	1.00e+00	3.715	1	10	183
GO:0016071	mRNA metabolic process	8.93e-02	1.00e+00	3.430	1	31	223
GO:0007067	mitotic nuclear division	9.08e-02	1.00e+00	3.405	1	14	227
GO:0008380	RNA splicing	9.12e-02	1.00e+00	3.398	1	11	228
GO:0006412	translation	9.20e-02	1.00e+00	3.386	1	20	230
GO:0007399	nervous system development	9.23e-02	1.00e+00	3.379	1	5	231
GO:0005524	ATP binding	9.51e-02	1.00e+00	1.889	2	60	1298
GO:0016070	RNA metabolic process	9.85e-02	1.00e+00	3.283	1	32	247
GO:0004842	ubiquitin-protein transferase activity	1.02e-01	1.00e+00	3.237	1	6	255
GO:0000166	nucleotide binding	1.03e-01	1.00e+00	3.214	1	5	259
GO:0006281	DNA repair	1.04e-01	1.00e+00	3.203	1	18	261
GO:0003779	actin binding	1.06e-01	1.00e+00	3.176	1	12	266
GO:0004674	protein serine/threonine kinase activity	1.21e-01	1.00e+00	2.964	1	12	308
GO:0007275	multicellular organismal development	1.24e-01	1.00e+00	2.927	1	5	316
GO:0019901	protein kinase binding	1.25e-01	1.00e+00	2.923	1	21	317
GO:0007411	axon guidance	1.26e-01	1.00e+00	2.914	1	13	319
GO:0005813	centrosome	1.28e-01	1.00e+00	2.882	1	14	326
GO:0003723	RNA binding	1.34e-01	1.00e+00	2.813	1	20	342
GO:0005925	focal adhesion	1.43e-01	1.00e+00	2.715	1	19	366
GO:0007155	cell adhesion	1.44e-01	1.00e+00	2.704	1	6	369
GO:0007596	blood coagulation	1.75e-01	1.00e+00	2.401	1	18	455
GO:0006468	protein phosphorylation	1.77e-01	1.00e+00	2.386	1	18	460
GO:0042802	identical protein binding	1.85e-01	1.00e+00	2.312	1	20	484
GO:0005737	cytoplasm	1.87e-01	1.00e+00	0.937	3	110	3767
GO:0045087	innate immune response	2.24e-01	1.00e+00	2.012	1	24	596
GO:0005634	nucleus	2.86e-01	1.00e+00	0.662	3	136	4559
GO:0007165	signal transduction	3.23e-01	1.00e+00	1.406	1	24	907
GO:0005615	extracellular space	3.38e-01	1.00e+00	1.329	1	17	957
GO:0008270	zinc ion binding	3.49e-01	1.00e+00	1.270	1	12	997
GO:0005730	nucleolus	5.16e-01	1.00e+00	0.551	1	69	1641
GO:0005886	plasma membrane	6.94e-01	1.00e+00	-0.103	1	45	2582

Wolf-ratios-Mammosphere-Adherent

int-snw-8507

Statistics

Genes (6)

Interactions (6)

Related GO terms (124)