int-snw-6189

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
wolf-screen-ratio-mammosphere-adherent 1.069 3.78e-21 9.14e-05 3.18e-03
wolf-screen-ratio-mammosphere-adherent-int-snw-6189 subnetwork

Genes (5)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
ACTB 60 1671.1531.151587Yes-
SAP18 10284 81.1151.06957Yes-
RPS11 6205 360.9931.113175Yes-
RPL14 9045 421.2501.113143Yes-
[ RPS3A ] 6189 110.8351.069166Yes-

Interactions (5)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
RPS3A 6189 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPS3A 6189 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS3A 6189 SAP18 10284 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid, HPRD, MINT;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
RPS11 6205 RPL14 9045 pp -- int.I2D: BioGrid_Yeast

Related GO terms (85)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0019083viral transcription1.69e-062.44e-026.73931081
GO:0006415translational termination2.10e-063.03e-026.63631087
GO:0006414translational elongation2.57e-063.71e-026.54031393
GO:0006614SRP-dependent cotranslational protein targeting to membrane3.60e-065.20e-026.379310104
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay4.75e-066.86e-026.246311114
GO:0019058viral life cycle4.88e-067.04e-026.234313115
GO:0044267cellular protein metabolic process5.61e-068.09e-024.605429474
GO:0006413translational initiation7.23e-061.04e-016.046317131
GO:0003735structural constituent of ribosome8.27e-061.19e-015.981310137
GO:0016071mRNA metabolic process3.56e-055.14e-015.278331223
GO:0006412translation3.91e-055.64e-015.234320230
GO:0016070RNA metabolic process4.84e-056.98e-015.131332247
GO:0022627cytosolic small ribosomal subunit7.09e-051.00e+007.2092439
GO:0044822poly(A) RNA binding1.35e-041.00e+003.4504491056
GO:0005925focal adhesion1.56e-041.00e+004.563319366
GO:0016032viral process4.77e-041.00e+004.018355534
GO:0030529ribonucleoprotein complex5.89e-041.00e+005.68728112
GO:0010467gene expression9.26e-041.00e+003.693359669
GO:0061574ASAP complex1.04e-031.00e+009.909113
GO:0002181cytoplasmic translation2.08e-031.00e+008.909116
GO:0030957Tat protein binding2.08e-031.00e+008.909136
GO:0070688MLL5-L complex2.77e-031.00e+008.494118
GO:0070062extracellular vesicular exosome3.32e-031.00e+002.26541042400
GO:0005829cytosol3.86e-031.00e+002.20941322496
GO:0042273ribosomal large subunit biogenesis4.50e-031.00e+007.7941413
GO:0035267NuA4 histone acetyltransferase complex4.84e-031.00e+007.6871414
GO:0048025negative regulation of mRNA splicing, via spliceosome5.19e-031.00e+007.5871115
GO:0003723RNA binding5.35e-031.00e+004.076220342
GO:0050998nitric-oxide synthase binding5.54e-031.00e+007.4941116
GO:0035145exon-exon junction complex6.57e-031.00e+007.2461119
GO:0030863cortical cytoskeleton7.60e-031.00e+007.0351122
GO:0036464cytoplasmic ribonucleoprotein granule7.60e-031.00e+007.0351422
GO:0043044ATP-dependent chromatin remodeling7.95e-031.00e+006.9711423
GO:0000381regulation of alternative mRNA splicing, via spliceosome8.98e-031.00e+006.7941126
GO:0031492nucleosomal DNA binding9.33e-031.00e+006.7391427
GO:0019843rRNA binding9.33e-031.00e+006.7391327
GO:0000118histone deacetylase complex9.67e-031.00e+006.6871128
GO:0019894kinesin binding9.67e-031.00e+006.6871128
GO:1903507negative regulation of nucleic acid-templated transcription1.10e-021.00e+006.4941232
GO:0001895retina homeostasis1.17e-021.00e+006.4071134
GO:0034332adherens junction organization1.24e-021.00e+006.3241136
GO:0005515protein binding1.27e-021.00e+001.26051846024
GO:0051084'de novo' posttranslational protein folding1.28e-021.00e+006.2851437
GO:0070527platelet aggregation1.31e-021.00e+006.2461238
GO:0016020membrane1.32e-021.00e+002.3643901681
GO:0021762substantia nigra development1.52e-021.00e+006.0351244
GO:0022625cytosolic large ribosomal subunit1.69e-021.00e+005.8791649
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding1.82e-021.00e+005.7661553
GO:0005737cytoplasm1.84e-021.00e+001.61541103767
GO:0045216cell-cell junction organization1.86e-021.00e+005.7391254
GO:0005840ribosome1.99e-021.00e+005.6361158
GO:0034329cell junction assembly2.34e-021.00e+005.4071168
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis2.54e-021.00e+005.2851674
GO:0005200structural constituent of cytoskeleton3.12e-021.00e+004.9861891
GO:0006928cellular component movement3.12e-021.00e+004.9861791
GO:0001649osteoblast differentiation3.15e-021.00e+004.9711692
GO:0006364rRNA processing3.22e-021.00e+004.9401694
GO:0014069postsynaptic density3.59e-021.00e+004.78013105
GO:0072562blood microparticle3.79e-021.00e+004.70013111
GO:0006325chromatin organization4.02e-021.00e+004.61215118
GO:0000790nuclear chromatin4.39e-021.00e+004.48319129
GO:0006457protein folding4.86e-021.00e+004.33417143
GO:0061024membrane organization4.93e-021.00e+004.31417145
GO:0006397mRNA processing5.43e-021.00e+004.17212160
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding5.59e-021.00e+004.12817165
GO:0030424axon5.62e-021.00e+004.11914166
GO:0016607nuclear speck5.82e-021.00e+004.06813172
GO:0003714transcription corepressor activity6.02e-021.00e+004.01818178
GO:0008380RNA splicing7.66e-021.00e+003.661111228
GO:0006357regulation of transcription from RNA polymerase II promoter8.82e-021.00e+003.45018264
GO:0043065positive regulation of apoptotic process8.95e-021.00e+003.428110268
GO:0005856cytoskeleton9.69e-021.00e+003.309112291
GO:0043234protein complex9.82e-021.00e+003.290118295
GO:0030154cell differentiation1.00e-011.00e+003.26115301
GO:0005730nucleolus1.02e-011.00e+001.8142691641
GO:0019901protein kinase binding1.05e-011.00e+003.186121317
GO:0007411axon guidance1.06e-011.00e+003.177113319
GO:0043066negative regulation of apoptotic process1.39e-011.00e+002.766131424
GO:0007596blood coagulation1.48e-011.00e+002.664118455
GO:0045087innate immune response1.90e-011.00e+002.275124596
GO:0005615extracellular space2.91e-011.00e+001.592117957
GO:0005654nucleoplasm3.23e-011.00e+001.4151761082
GO:0005524ATP binding3.76e-011.00e+001.1521601298
GO:0006351transcription, DNA-templated4.10e-011.00e+000.9961311446
GO:0005634nucleus5.05e-011.00e+000.34021364559