int-snw-5901

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.994	6.93e-18	6.37e-04	1.46e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-5901 subnetwork

Genes (7)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
CAD	790	17	0.807	1.007	333	-	-
ACTB	60	167	1.153	1.151	587	Yes	-
OGDH	4967	13	0.847	1.076	113	Yes	-
[ RAN ]	5901	5	0.632	0.994	175	Yes	-
RPS11	6205	36	0.993	1.113	175	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-
PGD	5226	75	1.201	1.106	138	Yes	-

Interactions (11)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CAD	790	RPSA	3921	pp	--	int.I2D: IntAct_Yeast
RPSA	3921	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB	60	RAN	5901	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, NON_CORE
OGDH	4967	RAN	5901	pp	--	int.I2D: YeastLow
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
CAD	790	RAN	5901	pp	--	int.I2D: IntAct_Yeast
OGDH	4967	PGD	5226	pp	--	int.I2D: YeastLow
RAN	5901	RPS11	6205	pp	--	int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, MINT_Worm, NON_CORE
RPSA	3921	RAN	5901	pp	--	int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
PGD	5226	RAN	5901	pp	--	int.I2D: YeastLow
ACTB	60	CAD	790	pp	--	int.I2D: IntAct_Yeast

Related GO terms (168)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0019058	viral life cycle	1.69e-05	2.44e-01	5.748	3	13	115
GO:0070062	extracellular vesicular exosome	1.27e-04	1.00e+00	2.365	6	104	2400
GO:0022627	cytosolic small ribosomal subunit	1.48e-04	1.00e+00	6.723	2	4	39
GO:0005829	cytosol	1.59e-04	1.00e+00	2.308	6	132	2496
GO:0016020	membrane	3.67e-04	1.00e+00	2.616	5	90	1681
GO:0004151	dihydroorotase activity	4.85e-04	1.00e+00	11.009	1	1	1
GO:0019521	D-gluconate metabolic process	4.85e-04	1.00e+00	11.009	1	1	1
GO:0004070	aspartate carbamoyltransferase activity	4.85e-04	1.00e+00	11.009	1	1	1
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	4.85e-04	1.00e+00	11.009	1	1	1
GO:0034602	oxoglutarate dehydrogenase (NAD+) activity	4.85e-04	1.00e+00	11.009	1	1	1
GO:0070335	aspartate binding	4.85e-04	1.00e+00	11.009	1	1	1
GO:0019083	viral transcription	6.42e-04	1.00e+00	5.669	2	10	81
GO:0006415	translational termination	7.41e-04	1.00e+00	5.566	2	10	87
GO:0006414	translational elongation	8.46e-04	1.00e+00	5.470	2	13	93
GO:0061034	olfactory bulb mitral cell layer development	9.70e-04	1.00e+00	10.009	1	1	2
GO:0045252	oxoglutarate dehydrogenase complex	9.70e-04	1.00e+00	10.009	1	2	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	9.70e-04	1.00e+00	10.009	1	1	2
GO:0019322	pentose biosynthetic process	9.70e-04	1.00e+00	10.009	1	2	2
GO:0005055	laminin receptor activity	9.70e-04	1.00e+00	10.009	1	1	2
GO:0006407	rRNA export from nucleus	9.70e-04	1.00e+00	10.009	1	1	2
GO:0070409	carbamoyl phosphate biosynthetic process	9.70e-04	1.00e+00	10.009	1	1	2
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.06e-03	1.00e+00	5.308	2	10	104
GO:0044267	cellular protein metabolic process	1.12e-03	1.00e+00	3.705	3	29	474
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.27e-03	1.00e+00	5.176	2	11	114
GO:0044281	small molecule metabolic process	1.41e-03	1.00e+00	2.767	4	58	1211
GO:0000056	ribosomal small subunit export from nucleus	1.46e-03	1.00e+00	9.424	1	1	3
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	1.46e-03	1.00e+00	9.424	1	1	3
GO:0009051	pentose-phosphate shunt, oxidative branch	1.46e-03	1.00e+00	9.424	1	2	3
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	1.46e-03	1.00e+00	9.424	1	1	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	1.46e-03	1.00e+00	9.424	1	1	3
GO:0044205	'de novo' UMP biosynthetic process	1.46e-03	1.00e+00	9.424	1	1	3
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	1.46e-03	1.00e+00	9.424	1	1	3
GO:0016032	viral process	1.58e-03	1.00e+00	3.533	3	55	534
GO:0006413	translational initiation	1.67e-03	1.00e+00	4.975	2	17	131
GO:0003735	structural constituent of ribosome	1.82e-03	1.00e+00	4.911	2	10	137
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.94e-03	1.00e+00	9.009	1	1	4
GO:0030686	90S preribosome	1.94e-03	1.00e+00	9.009	1	1	4
GO:0006104	succinyl-CoA metabolic process	1.94e-03	1.00e+00	9.009	1	1	4
GO:0006543	glutamine catabolic process	1.94e-03	1.00e+00	9.009	1	1	4
GO:0000055	ribosomal large subunit export from nucleus	1.94e-03	1.00e+00	9.009	1	1	4
GO:0006734	NADH metabolic process	1.94e-03	1.00e+00	9.009	1	1	4
GO:0051414	response to cortisol	2.42e-03	1.00e+00	8.687	1	1	5
GO:0030976	thiamine pyrophosphate binding	2.42e-03	1.00e+00	8.687	1	1	5
GO:0021695	cerebellar cortex development	2.91e-03	1.00e+00	8.424	1	2	6
GO:0030957	Tat protein binding	2.91e-03	1.00e+00	8.424	1	3	6
GO:0046134	pyrimidine nucleoside biosynthetic process	2.91e-03	1.00e+00	8.424	1	1	6
GO:0021860	pyramidal neuron development	2.91e-03	1.00e+00	8.424	1	1	6
GO:0010467	gene expression	3.02e-03	1.00e+00	3.208	3	59	669
GO:0000028	ribosomal small subunit assembly	3.39e-03	1.00e+00	8.201	1	1	7
GO:0070688	MLL5-L complex	3.88e-03	1.00e+00	8.009	1	1	8
GO:0006554	lysine catabolic process	3.88e-03	1.00e+00	8.009	1	2	8
GO:0006228	UTP biosynthetic process	4.36e-03	1.00e+00	7.839	1	1	9
GO:0014075	response to amine	4.36e-03	1.00e+00	7.839	1	1	9
GO:0031000	response to caffeine	4.36e-03	1.00e+00	7.839	1	2	9
GO:0016071	mRNA metabolic process	4.75e-03	1.00e+00	4.208	2	31	223
GO:0006098	pentose-phosphate shunt	4.84e-03	1.00e+00	7.687	1	4	10
GO:0021756	striatum development	4.84e-03	1.00e+00	7.687	1	1	10
GO:0006412	translation	5.04e-03	1.00e+00	4.163	2	20	230
GO:0021794	thalamus development	5.33e-03	1.00e+00	7.549	1	1	11
GO:0016070	RNA metabolic process	5.80e-03	1.00e+00	4.060	2	32	247
GO:0035267	NuA4 histone acetyltransferase complex	6.78e-03	1.00e+00	7.201	1	4	14
GO:0050998	nitric-oxide synthase binding	7.74e-03	1.00e+00	7.009	1	1	16
GO:0006103	2-oxoglutarate metabolic process	7.74e-03	1.00e+00	7.009	1	1	16
GO:0043234	protein complex	8.18e-03	1.00e+00	3.804	2	18	295
GO:0075733	intracellular transport of virus	8.22e-03	1.00e+00	6.921	1	3	17
GO:0006541	glutamine metabolic process	8.22e-03	1.00e+00	6.921	1	1	17
GO:0017144	drug metabolic process	8.71e-03	1.00e+00	6.839	1	1	18
GO:0006259	DNA metabolic process	9.19e-03	1.00e+00	6.761	1	2	19
GO:0071364	cellular response to epidermal growth factor stimulus	1.01e-02	1.00e+00	6.616	1	1	21
GO:0006206	pyrimidine nucleobase metabolic process	1.06e-02	1.00e+00	6.549	1	2	22
GO:0033574	response to testosterone	1.06e-02	1.00e+00	6.549	1	2	22
GO:0030863	cortical cytoskeleton	1.06e-02	1.00e+00	6.549	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	1.06e-02	1.00e+00	6.549	1	4	22
GO:0007052	mitotic spindle organization	1.06e-02	1.00e+00	6.549	1	2	22
GO:0044822	poly(A) RNA binding	1.10e-02	1.00e+00	2.549	3	49	1056
GO:0043044	ATP-dependent chromatin remodeling	1.11e-02	1.00e+00	6.485	1	4	23
GO:0043236	laminin binding	1.11e-02	1.00e+00	6.485	1	1	23
GO:0006611	protein export from nucleus	1.21e-02	1.00e+00	6.365	1	3	25
GO:0005925	focal adhesion	1.24e-02	1.00e+00	3.493	2	19	366
GO:0019843	rRNA binding	1.30e-02	1.00e+00	6.254	1	3	27
GO:0043022	ribosome binding	1.30e-02	1.00e+00	6.254	1	3	27
GO:0050661	NADP binding	1.30e-02	1.00e+00	6.254	1	2	27
GO:0031492	nucleosomal DNA binding	1.30e-02	1.00e+00	6.254	1	4	27
GO:0006099	tricarboxylic acid cycle	1.35e-02	1.00e+00	6.201	1	4	28
GO:0019894	kinesin binding	1.35e-02	1.00e+00	6.201	1	1	28
GO:0031072	heat shock protein binding	1.59e-02	1.00e+00	5.964	1	1	33
GO:0001895	retina homeostasis	1.64e-02	1.00e+00	5.921	1	1	34
GO:0034332	adherens junction organization	1.73e-02	1.00e+00	5.839	1	1	36
GO:0018107	peptidyl-threonine phosphorylation	1.78e-02	1.00e+00	5.799	1	4	37
GO:0051084	'de novo' posttranslational protein folding	1.78e-02	1.00e+00	5.799	1	4	37
GO:0021766	hippocampus development	1.83e-02	1.00e+00	5.761	1	4	38
GO:0006096	glycolytic process	1.83e-02	1.00e+00	5.761	1	4	38
GO:0032092	positive regulation of protein binding	1.83e-02	1.00e+00	5.761	1	3	38
GO:0070527	platelet aggregation	1.83e-02	1.00e+00	5.761	1	2	38
GO:0050681	androgen receptor binding	1.83e-02	1.00e+00	5.761	1	3	38
GO:0007595	lactation	1.88e-02	1.00e+00	5.723	1	2	39
GO:0007286	spermatid development	1.97e-02	1.00e+00	5.651	1	1	41
GO:0030521	androgen receptor signaling pathway	1.97e-02	1.00e+00	5.651	1	1	41
GO:0043195	terminal bouton	1.97e-02	1.00e+00	5.651	1	1	41
GO:0021762	substantia nigra development	2.12e-02	1.00e+00	5.549	1	2	44
GO:0019003	GDP binding	2.26e-02	1.00e+00	5.454	1	2	47
GO:0035690	cellular response to drug	2.35e-02	1.00e+00	5.394	1	2	49
GO:0006091	generation of precursor metabolites and energy	2.40e-02	1.00e+00	5.365	1	3	50
GO:0031100	organ regeneration	2.40e-02	1.00e+00	5.365	1	4	50
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.54e-02	1.00e+00	5.281	1	5	53
GO:0045216	cell-cell junction organization	2.59e-02	1.00e+00	5.254	1	2	54
GO:0031966	mitochondrial membrane	2.64e-02	1.00e+00	5.227	1	1	55
GO:0005643	nuclear pore	2.73e-02	1.00e+00	5.176	1	4	57
GO:0005840	ribosome	2.78e-02	1.00e+00	5.151	1	1	58
GO:0051087	chaperone binding	2.83e-02	1.00e+00	5.126	1	6	59
GO:0042995	cell projection	2.88e-02	1.00e+00	5.102	1	6	60
GO:0034329	cell junction assembly	3.25e-02	1.00e+00	4.921	1	1	68
GO:0055086	nucleobase-containing small molecule metabolic process	3.35e-02	1.00e+00	4.879	1	2	70
GO:0000785	chromatin	3.49e-02	1.00e+00	4.819	1	4	73
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	3.54e-02	1.00e+00	4.799	1	6	74
GO:0001889	liver development	3.68e-02	1.00e+00	4.742	1	4	77
GO:0007565	female pregnancy	3.73e-02	1.00e+00	4.723	1	1	78
GO:0042470	melanosome	4.33e-02	1.00e+00	4.501	1	9	91
GO:0016363	nuclear matrix	4.33e-02	1.00e+00	4.501	1	12	91
GO:0006928	cellular component movement	4.33e-02	1.00e+00	4.501	1	7	91
GO:0005200	structural constituent of cytoskeleton	4.33e-02	1.00e+00	4.501	1	8	91
GO:0001649	osteoblast differentiation	4.38e-02	1.00e+00	4.485	1	6	92
GO:0014069	postsynaptic density	4.99e-02	1.00e+00	4.294	1	3	105
GO:0072562	blood microparticle	5.27e-02	1.00e+00	4.214	1	3	111
GO:0030529	ribonucleoprotein complex	5.31e-02	1.00e+00	4.201	1	8	112
GO:0044237	cellular metabolic process	5.54e-02	1.00e+00	4.138	1	5	117
GO:0006325	chromatin organization	5.59e-02	1.00e+00	4.126	1	5	118
GO:0000790	nuclear chromatin	6.10e-02	1.00e+00	3.998	1	9	129
GO:0007507	heart development	6.56e-02	1.00e+00	3.890	1	7	139
GO:0006457	protein folding	6.74e-02	1.00e+00	3.849	1	7	143
GO:0061024	membrane organization	6.83e-02	1.00e+00	3.829	1	7	145
GO:0046777	protein autophosphorylation	7.42e-02	1.00e+00	3.705	1	7	158
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	7.74e-02	1.00e+00	3.642	1	7	165
GO:0030424	axon	7.79e-02	1.00e+00	3.634	1	4	166
GO:0034641	cellular nitrogen compound metabolic process	8.01e-02	1.00e+00	3.591	1	20	171
GO:0004672	protein kinase activity	8.28e-02	1.00e+00	3.541	1	6	177
GO:0019904	protein domain specific binding	8.37e-02	1.00e+00	3.525	1	6	179
GO:0005654	nucleoplasm	9.17e-02	1.00e+00	1.929	2	76	1082
GO:0003924	GTPase activity	9.18e-02	1.00e+00	3.387	1	12	197
GO:0006184	GTP catabolic process	9.94e-02	1.00e+00	3.267	1	12	214
GO:0007067	mitotic nuclear division	1.05e-01	1.00e+00	3.182	1	14	227
GO:0005759	mitochondrial matrix	1.06e-01	1.00e+00	3.176	1	14	228
GO:0003713	transcription coactivator activity	1.10e-01	1.00e+00	3.120	1	10	237
GO:0043025	neuronal cell body	1.13e-01	1.00e+00	3.072	1	9	245
GO:0005975	carbohydrate metabolic process	1.17e-01	1.00e+00	3.026	1	9	253
GO:0005524	ATP binding	1.25e-01	1.00e+00	1.667	2	60	1298
GO:0019899	enzyme binding	1.27e-01	1.00e+00	2.895	1	12	277
GO:0007264	small GTPase mediated signal transduction	1.28e-01	1.00e+00	2.885	1	4	279
GO:0005856	cytoskeleton	1.33e-01	1.00e+00	2.824	1	12	291
GO:0005525	GTP binding	1.41e-01	1.00e+00	2.733	1	12	310
GO:0019901	protein kinase binding	1.44e-01	1.00e+00	2.700	1	21	317
GO:0007411	axon guidance	1.45e-01	1.00e+00	2.691	1	13	319
GO:0003682	chromatin binding	1.48e-01	1.00e+00	2.656	1	11	327
GO:0005634	nucleus	1.48e-01	1.00e+00	0.854	4	136	4559
GO:0007155	cell adhesion	1.66e-01	1.00e+00	2.481	1	6	369
GO:0055114	oxidation-reduction process	1.87e-01	1.00e+00	2.294	1	12	420
GO:0007596	blood coagulation	2.01e-01	1.00e+00	2.179	1	18	455
GO:0045893	positive regulation of transcription, DNA-templated	2.10e-01	1.00e+00	2.108	1	13	478
GO:0042802	identical protein binding	2.13e-01	1.00e+00	2.090	1	20	484
GO:0045087	innate immune response	2.56e-01	1.00e+00	1.790	1	24	596
GO:0005737	cytoplasm	2.67e-01	1.00e+00	0.714	3	110	3767
GO:0005515	protein binding	3.25e-01	1.00e+00	0.452	4	184	6024
GO:0007165	signal transduction	3.65e-01	1.00e+00	1.184	1	24	907
GO:0005615	extracellular space	3.82e-01	1.00e+00	1.106	1	17	957
GO:0008270	zinc ion binding	3.94e-01	1.00e+00	1.047	1	12	997
GO:0005739	mitochondrion	3.95e-01	1.00e+00	1.046	1	28	998
GO:0046872	metal ion binding	4.86e-01	1.00e+00	0.657	1	25	1307
GO:0005886	plasma membrane	7.49e-01	1.00e+00	-0.326	1	45	2582

Wolf-ratios-Mammosphere-Adherent

int-snw-5901

Statistics

Genes (7)

Interactions (11)

Related GO terms (168)