Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
wolf-screen-ratio-mammosphere-adherent | 0.958 | 2.11e-16 | 1.50e-03 | 2.78e-02 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
ACO2 | 50 | 50 | 1.000 | 1.076 | 191 | Yes | - |
PSMA3 | 5684 | 12 | 0.533 | 1.026 | 218 | Yes | - |
PPARG | 5468 | 1 | -0.535 | 0.958 | 131 | - | Yes |
PSMA2 | 5683 | 60 | 1.093 | 1.106 | 89 | Yes | - |
PSMD3 | 5709 | 57 | 0.986 | 1.106 | 146 | Yes | - |
HNRNPC | 3183 | 20 | 1.812 | 1.026 | 119 | Yes | - |
PSMB7 | 5695 | 48 | 0.982 | 1.052 | 57 | Yes | - |
PSMA1 | 5682 | 61 | 0.996 | 1.052 | 123 | Yes | - |
PSMD11 | 5717 | 121 | 1.095 | 1.106 | 183 | Yes | - |
ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
HSPD1 | 3329 | 35 | 0.913 | 1.035 | 286 | Yes | - |
PSMD6 | 9861 | 11 | 0.848 | 1.009 | 131 | Yes | - |
RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - |
[ PRNP ] | 5621 | 1 | -0.135 | 0.958 | 89 | - | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
PSMA2 | 5683 | PSMA3 | 5684 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD; int.HPRD: yeast 2-hybrid |
PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
PSMA3 | 5684 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
PSMA3 | 5684 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, YeastLow |
ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA1 | 5682 | PSMA2 | 5683 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
PSMB7 | 5695 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct |
PSMD11 | 5717 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, INTEROLOG |
PSMA1 | 5682 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, YeastMedium |
PPARG | 5468 | PRNP | 5621 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA2 | 5683 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast |
HSPD1 | 3329 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid |
ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
ACO2 | 50 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
HSPD1 | 3329 | RPSA | 3921 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
PSMA2 | 5683 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, YeastLow, BioGrid |
PSMA2 | 5683 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
PRNP | 5621 | PSMD6 | 9861 | pp | -- | int.I2D: MINT_Mouse |
PSMA1 | 5682 | PSMA3 | 5684 | pp | -- | int.Intact: MI:0914(association), MI:0915(physical association); int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd; int.HPRD: in vitro |
PSMA3 | 5684 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
ACO2 | 50 | HSPD1 | 3329 | pp | -- | int.I2D: IntAct_Yeast |
PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast |
PSMA2 | 5683 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PRNP | 5621 | PSMA3 | 5684 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: HPRD, MINT, IntAct; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid |
HNRNPC | 3183 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid |
ACTB | 60 | PSMD6 | 9861 | pp | -- | int.I2D: BioGrid_Yeast |
PSMD3 | 5709 | PSMD6 | 9861 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Yeast, MINT_Worm, MINT_Yeast, YeastHigh, BioGrid, BIND_Yeast, IntAct_Worm, INTEROLOG, Krogan_Core, MIPS |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | HSPD1 | 3329 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastLow |
PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA3 | 5684 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core |
HSPD1 | 3329 | PRNP | 5621 | pp | -- | int.I2D: BIND, HPRD, BCI; int.HPRD: in vitro, in vivo |
ACTB | 60 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid, BioGrid_Yeast |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0006521 | regulation of cellular amino acid metabolic process | 1.31e-14 | 1.89e-10 | 7.172 | 7 | 17 | 50 |
GO:0000502 | proteasome complex | 3.93e-14 | 5.66e-10 | 6.958 | 7 | 17 | 58 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 8.09e-14 | 1.17e-09 | 6.816 | 7 | 19 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 9.06e-14 | 1.31e-09 | 6.794 | 7 | 22 | 65 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.56e-13 | 2.25e-09 | 6.687 | 7 | 22 | 70 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 1.91e-13 | 2.76e-09 | 6.646 | 7 | 20 | 72 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 2.33e-13 | 3.37e-09 | 6.607 | 7 | 22 | 74 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 2.57e-13 | 3.71e-09 | 6.587 | 7 | 20 | 75 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 3.75e-13 | 5.41e-09 | 6.512 | 7 | 23 | 79 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 1.13e-12 | 1.63e-08 | 6.293 | 7 | 21 | 92 |
GO:0000209 | protein polyubiquitination | 5.94e-12 | 8.57e-08 | 5.958 | 7 | 20 | 116 |
GO:0016071 | mRNA metabolic process | 7.99e-12 | 1.15e-07 | 5.208 | 8 | 31 | 223 |
GO:0016070 | RNA metabolic process | 1.82e-11 | 2.62e-07 | 5.060 | 8 | 32 | 247 |
GO:0043066 | negative regulation of apoptotic process | 2.65e-11 | 3.82e-07 | 4.451 | 9 | 31 | 424 |
GO:0000082 | G1/S transition of mitotic cell cycle | 3.52e-11 | 5.08e-07 | 5.597 | 7 | 32 | 149 |
GO:0010467 | gene expression | 3.65e-11 | 5.27e-07 | 3.945 | 10 | 59 | 669 |
GO:0042981 | regulation of apoptotic process | 3.69e-11 | 5.32e-07 | 5.587 | 7 | 24 | 150 |
GO:0034641 | cellular nitrogen compound metabolic process | 9.32e-11 | 1.34e-06 | 5.398 | 7 | 20 | 171 |
GO:0016032 | viral process | 2.08e-10 | 2.99e-06 | 4.118 | 9 | 55 | 534 |
GO:0005839 | proteasome core complex | 1.69e-09 | 2.43e-05 | 7.839 | 4 | 8 | 18 |
GO:0004298 | threonine-type endopeptidase activity | 2.13e-09 | 3.08e-05 | 7.761 | 4 | 8 | 19 |
GO:0005654 | nucleoplasm | 4.11e-09 | 5.93e-05 | 3.251 | 10 | 76 | 1082 |
GO:0070062 | extracellular vesicular exosome | 2.88e-08 | 4.15e-04 | 2.365 | 12 | 104 | 2400 |
GO:0000278 | mitotic cell cycle | 2.97e-08 | 4.29e-04 | 4.205 | 7 | 48 | 391 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 4.07e-08 | 5.86e-04 | 8.594 | 3 | 4 | 8 |
GO:0005829 | cytosol | 4.54e-08 | 6.55e-04 | 2.308 | 12 | 132 | 2496 |
GO:0006915 | apoptotic process | 3.26e-07 | 4.71e-03 | 3.700 | 7 | 33 | 555 |
GO:0022624 | proteasome accessory complex | 4.91e-07 | 7.08e-03 | 7.506 | 3 | 8 | 17 |
GO:0044281 | small molecule metabolic process | 4.58e-06 | 6.60e-02 | 2.767 | 8 | 58 | 1211 |
GO:0005838 | proteasome regulatory particle | 5.74e-05 | 8.28e-01 | 7.424 | 2 | 7 | 12 |
GO:0043044 | ATP-dependent chromatin remodeling | 2.19e-04 | 1.00e+00 | 6.485 | 2 | 4 | 23 |
GO:0031492 | nucleosomal DNA binding | 3.03e-04 | 1.00e+00 | 6.254 | 2 | 4 | 27 |
GO:0005634 | nucleus | 4.09e-04 | 1.00e+00 | 1.314 | 11 | 136 | 4559 |
GO:2000230 | negative regulation of pancreatic stellate cell proliferation | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:0002842 | positive regulation of T cell mediated immune response to tumor cell | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:0004955 | prostaglandin receptor activity | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:0048291 | isotype switching to IgG isotypes | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:0060694 | regulation of cholesterol transporter activity | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:0045713 | low-density lipoprotein particle receptor biosynthetic process | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:1901558 | response to metformin | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:0036270 | response to diuretic | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:0002368 | B cell cytokine production | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 1.17e-03 | 1.00e+00 | 5.281 | 2 | 5 | 53 |
GO:0051087 | chaperone binding | 1.45e-03 | 1.00e+00 | 5.126 | 2 | 6 | 59 |
GO:0051538 | 3 iron, 4 sulfur cluster binding | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:0071306 | cellular response to vitamin E | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:0003994 | aconitate hydratase activity | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process | 2.46e-03 | 1.00e+00 | 4.742 | 2 | 7 | 77 |
GO:0043234 | protein complex | 2.61e-03 | 1.00e+00 | 3.389 | 3 | 18 | 295 |
GO:0055098 | response to low-density lipoprotein particle | 2.91e-03 | 1.00e+00 | 8.424 | 1 | 1 | 3 |
GO:0001012 | RNA polymerase II regulatory region DNA binding | 2.91e-03 | 1.00e+00 | 8.424 | 1 | 1 | 3 |
GO:0010871 | negative regulation of receptor biosynthetic process | 2.91e-03 | 1.00e+00 | 8.424 | 1 | 1 | 3 |
GO:0046321 | positive regulation of fatty acid oxidation | 2.91e-03 | 1.00e+00 | 8.424 | 1 | 1 | 3 |
GO:0006458 | 'de novo' protein folding | 2.91e-03 | 1.00e+00 | 8.424 | 1 | 1 | 3 |
GO:0030135 | coated vesicle | 2.91e-03 | 1.00e+00 | 8.424 | 1 | 1 | 3 |
GO:0016020 | membrane | 3.25e-03 | 1.00e+00 | 1.879 | 6 | 90 | 1681 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 3.88e-03 | 1.00e+00 | 8.009 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 3.88e-03 | 1.00e+00 | 8.009 | 1 | 1 | 4 |
GO:0070885 | negative regulation of calcineurin-NFAT signaling cascade | 3.88e-03 | 1.00e+00 | 8.009 | 1 | 1 | 4 |
GO:0035357 | peroxisome proliferator activated receptor signaling pathway | 3.88e-03 | 1.00e+00 | 8.009 | 1 | 1 | 4 |
GO:0060100 | positive regulation of phagocytosis, engulfment | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0032966 | negative regulation of collagen biosynthetic process | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0010891 | negative regulation of sequestering of triglyceride | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0043248 | proteasome assembly | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0046696 | lipopolysaccharide receptor complex | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0050544 | arachidonic acid binding | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0060336 | negative regulation of interferon-gamma-mediated signaling pathway | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0006102 | isocitrate metabolic process | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0060850 | regulation of transcription involved in cell fate commitment | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0005515 | protein binding | 5.80e-03 | 1.00e+00 | 0.912 | 11 | 184 | 6024 |
GO:0003688 | DNA replication origin binding | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 2 | 6 |
GO:1901379 | regulation of potassium ion transmembrane transport | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 1 | 6 |
GO:0006101 | citrate metabolic process | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 1 | 6 |
GO:0033993 | response to lipid | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 2 | 6 |
GO:0030957 | Tat protein binding | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 3 | 6 |
GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 1 | 6 |
GO:0010887 | negative regulation of cholesterol storage | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 1 | 6 |
GO:0046007 | negative regulation of activated T cell proliferation | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 1 | 6 |
GO:0000790 | nuclear chromatin | 6.73e-03 | 1.00e+00 | 3.998 | 2 | 9 | 129 |
GO:0000028 | ribosomal small subunit assembly | 6.78e-03 | 1.00e+00 | 7.201 | 1 | 1 | 7 |
GO:0043008 | ATP-dependent protein binding | 6.78e-03 | 1.00e+00 | 7.201 | 1 | 1 | 7 |
GO:0002674 | negative regulation of acute inflammatory response | 6.78e-03 | 1.00e+00 | 7.201 | 1 | 1 | 7 |
GO:0071455 | cellular response to hyperoxia | 6.78e-03 | 1.00e+00 | 7.201 | 1 | 1 | 7 |
GO:0015909 | long-chain fatty acid transport | 6.78e-03 | 1.00e+00 | 7.201 | 1 | 1 | 7 |
GO:0051974 | negative regulation of telomerase activity | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 2 | 8 |
GO:0070688 | MLL5-L complex | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 1 | 8 |
GO:0051604 | protein maturation | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 1 | 8 |
GO:0016887 | ATPase activity | 7.89e-03 | 1.00e+00 | 3.879 | 2 | 7 | 140 |
GO:0031000 | response to caffeine | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 2 | 9 |
GO:0071380 | cellular response to prostaglandin E stimulus | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 1 | 9 |
GO:0032703 | negative regulation of interleukin-2 production | 9.67e-03 | 1.00e+00 | 6.687 | 1 | 1 | 10 |
GO:0043032 | positive regulation of macrophage activation | 9.67e-03 | 1.00e+00 | 6.687 | 1 | 1 | 10 |
GO:0050872 | white fat cell differentiation | 9.67e-03 | 1.00e+00 | 6.687 | 1 | 1 | 10 |
GO:0032700 | negative regulation of interleukin-17 production | 9.67e-03 | 1.00e+00 | 6.687 | 1 | 1 | 10 |
GO:0032727 | positive regulation of interferon-alpha production | 1.06e-02 | 1.00e+00 | 6.549 | 1 | 1 | 11 |
GO:0019395 | fatty acid oxidation | 1.06e-02 | 1.00e+00 | 6.549 | 1 | 1 | 11 |
GO:0048714 | positive regulation of oligodendrocyte differentiation | 1.06e-02 | 1.00e+00 | 6.549 | 1 | 2 | 11 |
GO:0045120 | pronucleus | 1.06e-02 | 1.00e+00 | 6.549 | 1 | 2 | 11 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.08e-02 | 1.00e+00 | 3.642 | 2 | 7 | 165 |
GO:0006878 | cellular copper ion homeostasis | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 1 | 12 |
GO:0070935 | 3'-UTR-mediated mRNA stabilization | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 2 | 12 |
GO:0042953 | lipoprotein transport | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 1 | 12 |
GO:0046688 | response to copper ion | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 1 | 13 |
GO:0010745 | negative regulation of macrophage derived foam cell differentiation | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 2 | 13 |
GO:0050860 | negative regulation of T cell receptor signaling pathway | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 1 | 13 |
GO:0030234 | enzyme regulator activity | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 3 | 13 |
GO:0001530 | lipopolysaccharide binding | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 3 | 13 |
GO:0008266 | poly(U) RNA binding | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 1 | 13 |
GO:0051131 | chaperone-mediated protein complex assembly | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 1 | 13 |
GO:0033189 | response to vitamin A | 1.35e-02 | 1.00e+00 | 6.201 | 1 | 1 | 14 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.35e-02 | 1.00e+00 | 6.201 | 1 | 4 | 14 |
GO:0071285 | cellular response to lithium ion | 1.35e-02 | 1.00e+00 | 6.201 | 1 | 2 | 14 |
GO:0042026 | protein refolding | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 2 | 15 |
GO:0046965 | retinoid X receptor binding | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 1 | 15 |
GO:0042176 | regulation of protein catabolic process | 1.54e-02 | 1.00e+00 | 6.009 | 1 | 3 | 16 |
GO:0050998 | nitric-oxide synthase binding | 1.54e-02 | 1.00e+00 | 6.009 | 1 | 1 | 16 |
GO:0030224 | monocyte differentiation | 1.54e-02 | 1.00e+00 | 6.009 | 1 | 1 | 16 |
GO:0035902 | response to immobilization stress | 1.64e-02 | 1.00e+00 | 5.921 | 1 | 1 | 17 |
GO:0050870 | positive regulation of T cell activation | 1.64e-02 | 1.00e+00 | 5.921 | 1 | 1 | 17 |
GO:0055088 | lipid homeostasis | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 18 |
GO:0033613 | activating transcription factor binding | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 18 |
GO:0048863 | stem cell differentiation | 1.83e-02 | 1.00e+00 | 5.761 | 1 | 1 | 19 |
GO:0032733 | positive regulation of interleukin-10 production | 1.83e-02 | 1.00e+00 | 5.761 | 1 | 1 | 19 |
GO:0005759 | mitochondrial matrix | 2.00e-02 | 1.00e+00 | 3.176 | 2 | 14 | 228 |
GO:0042100 | B cell proliferation | 2.02e-02 | 1.00e+00 | 5.616 | 1 | 1 | 21 |
GO:0046686 | response to cadmium ion | 2.12e-02 | 1.00e+00 | 5.549 | 1 | 2 | 22 |
GO:0030863 | cortical cytoskeleton | 2.12e-02 | 1.00e+00 | 5.549 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 2.12e-02 | 1.00e+00 | 5.549 | 1 | 4 | 22 |
GO:0043236 | laminin binding | 2.21e-02 | 1.00e+00 | 5.485 | 1 | 1 | 23 |
GO:0005844 | polysome | 2.21e-02 | 1.00e+00 | 5.485 | 1 | 4 | 23 |
GO:0032689 | negative regulation of interferon-gamma production | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 1 | 24 |
GO:0042113 | B cell activation | 2.40e-02 | 1.00e+00 | 5.365 | 1 | 2 | 25 |
GO:0032735 | positive regulation of interleukin-12 production | 2.40e-02 | 1.00e+00 | 5.365 | 1 | 1 | 25 |
GO:0009409 | response to cold | 2.50e-02 | 1.00e+00 | 5.308 | 1 | 2 | 26 |
GO:0003730 | mRNA 3'-UTR binding | 2.50e-02 | 1.00e+00 | 5.308 | 1 | 2 | 26 |
GO:0015631 | tubulin binding | 2.59e-02 | 1.00e+00 | 5.254 | 1 | 1 | 27 |
GO:0030331 | estrogen receptor binding | 2.59e-02 | 1.00e+00 | 5.254 | 1 | 2 | 27 |
GO:0043022 | ribosome binding | 2.59e-02 | 1.00e+00 | 5.254 | 1 | 3 | 27 |
GO:0006099 | tricarboxylic acid cycle | 2.69e-02 | 1.00e+00 | 5.201 | 1 | 4 | 28 |
GO:0048662 | negative regulation of smooth muscle cell proliferation | 2.69e-02 | 1.00e+00 | 5.201 | 1 | 1 | 28 |
GO:0019894 | kinesin binding | 2.69e-02 | 1.00e+00 | 5.201 | 1 | 1 | 28 |
GO:0050873 | brown fat cell differentiation | 2.78e-02 | 1.00e+00 | 5.151 | 1 | 2 | 29 |
GO:0042594 | response to starvation | 2.97e-02 | 1.00e+00 | 5.055 | 1 | 1 | 31 |
GO:0001890 | placenta development | 2.97e-02 | 1.00e+00 | 5.055 | 1 | 1 | 31 |
GO:0045600 | positive regulation of fat cell differentiation | 3.06e-02 | 1.00e+00 | 5.009 | 1 | 1 | 32 |
GO:0006200 | ATP catabolic process | 3.17e-02 | 1.00e+00 | 2.819 | 2 | 15 | 292 |
GO:0007611 | learning or memory | 3.25e-02 | 1.00e+00 | 4.921 | 1 | 2 | 34 |
GO:0001895 | retina homeostasis | 3.25e-02 | 1.00e+00 | 4.921 | 1 | 1 | 34 |
GO:0051539 | 4 iron, 4 sulfur cluster binding | 3.35e-02 | 1.00e+00 | 4.879 | 1 | 3 | 35 |
GO:0034332 | adherens junction organization | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 1 | 36 |
GO:0001933 | negative regulation of protein phosphorylation | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 2 | 36 |
GO:0004879 | ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 1 | 36 |
GO:0032755 | positive regulation of interleukin-6 production | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 2 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 3.53e-02 | 1.00e+00 | 4.799 | 1 | 4 | 37 |
GO:0001228 | RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | 3.53e-02 | 1.00e+00 | 4.799 | 1 | 2 | 37 |
GO:0032880 | regulation of protein localization | 3.53e-02 | 1.00e+00 | 4.799 | 1 | 1 | 37 |
GO:0048469 | cell maturation | 3.63e-02 | 1.00e+00 | 4.761 | 1 | 1 | 38 |
GO:0070527 | platelet aggregation | 3.63e-02 | 1.00e+00 | 4.761 | 1 | 2 | 38 |
GO:0032729 | positive regulation of interferon-gamma production | 3.72e-02 | 1.00e+00 | 4.723 | 1 | 2 | 39 |
GO:0022627 | cytosolic small ribosomal subunit | 3.72e-02 | 1.00e+00 | 4.723 | 1 | 4 | 39 |
GO:0007411 | axon guidance | 3.72e-02 | 1.00e+00 | 2.691 | 2 | 13 | 319 |
GO:0042110 | T cell activation | 4.00e-02 | 1.00e+00 | 4.616 | 1 | 3 | 42 |
GO:0019898 | extrinsic component of membrane | 4.00e-02 | 1.00e+00 | 4.616 | 1 | 1 | 42 |
GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity | 4.10e-02 | 1.00e+00 | 4.582 | 1 | 1 | 43 |
GO:0021762 | substantia nigra development | 4.19e-02 | 1.00e+00 | 4.549 | 1 | 2 | 44 |
GO:0045165 | cell fate commitment | 4.19e-02 | 1.00e+00 | 4.549 | 1 | 1 | 44 |
GO:0003723 | RNA binding | 4.23e-02 | 1.00e+00 | 2.591 | 2 | 20 | 342 |
GO:0003707 | steroid hormone receptor activity | 4.28e-02 | 1.00e+00 | 4.517 | 1 | 1 | 45 |
GO:0032526 | response to retinoic acid | 4.38e-02 | 1.00e+00 | 4.485 | 1 | 2 | 46 |
GO:0005507 | copper ion binding | 4.38e-02 | 1.00e+00 | 4.485 | 1 | 2 | 46 |
GO:0006091 | generation of precursor metabolites and energy | 4.75e-02 | 1.00e+00 | 4.365 | 1 | 3 | 50 |
GO:0006986 | response to unfolded protein | 4.75e-02 | 1.00e+00 | 4.365 | 1 | 2 | 50 |
GO:0031100 | organ regeneration | 4.75e-02 | 1.00e+00 | 4.365 | 1 | 4 | 50 |
GO:0005905 | coated pit | 4.75e-02 | 1.00e+00 | 4.365 | 1 | 3 | 50 |
GO:0009612 | response to mechanical stimulus | 4.75e-02 | 1.00e+00 | 4.365 | 1 | 2 | 50 |
GO:0043401 | steroid hormone mediated signaling pathway | 4.84e-02 | 1.00e+00 | 4.336 | 1 | 1 | 51 |
GO:0003725 | double-stranded RNA binding | 4.93e-02 | 1.00e+00 | 4.308 | 1 | 5 | 52 |
GO:0045216 | cell-cell junction organization | 5.12e-02 | 1.00e+00 | 4.254 | 1 | 2 | 54 |
GO:0000932 | cytoplasmic mRNA processing body | 5.12e-02 | 1.00e+00 | 4.254 | 1 | 3 | 54 |
GO:0002039 | p53 binding | 5.21e-02 | 1.00e+00 | 4.227 | 1 | 7 | 55 |
GO:0071300 | cellular response to retinoic acid | 5.21e-02 | 1.00e+00 | 4.227 | 1 | 2 | 55 |
GO:0043627 | response to estrogen | 5.30e-02 | 1.00e+00 | 4.201 | 1 | 2 | 56 |
GO:0008217 | regulation of blood pressure | 5.40e-02 | 1.00e+00 | 4.176 | 1 | 4 | 57 |
GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity | 5.58e-02 | 1.00e+00 | 4.126 | 1 | 2 | 59 |
GO:0009986 | cell surface | 5.65e-02 | 1.00e+00 | 2.358 | 2 | 11 | 402 |
GO:0030855 | epithelial cell differentiation | 5.76e-02 | 1.00e+00 | 4.078 | 1 | 4 | 61 |
GO:0019903 | protein phosphatase binding | 5.86e-02 | 1.00e+00 | 4.055 | 1 | 4 | 62 |
GO:0030141 | secretory granule | 5.86e-02 | 1.00e+00 | 4.055 | 1 | 2 | 62 |
GO:0008144 | drug binding | 5.95e-02 | 1.00e+00 | 4.031 | 1 | 1 | 63 |
GO:0032869 | cellular response to insulin stimulus | 5.95e-02 | 1.00e+00 | 4.031 | 1 | 3 | 63 |
GO:0003697 | single-stranded DNA binding | 6.40e-02 | 1.00e+00 | 3.921 | 1 | 5 | 68 |
GO:0034329 | cell junction assembly | 6.40e-02 | 1.00e+00 | 3.921 | 1 | 1 | 68 |
GO:0005730 | nucleolus | 6.58e-02 | 1.00e+00 | 1.328 | 4 | 69 | 1641 |
GO:0007584 | response to nutrient | 6.68e-02 | 1.00e+00 | 3.859 | 1 | 4 | 71 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 6.95e-02 | 1.00e+00 | 3.799 | 1 | 6 | 74 |
GO:0071013 | catalytic step 2 spliceosome | 7.31e-02 | 1.00e+00 | 3.723 | 1 | 4 | 78 |
GO:0031225 | anchored component of membrane | 7.31e-02 | 1.00e+00 | 3.723 | 1 | 1 | 78 |
GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | 7.49e-02 | 1.00e+00 | 3.687 | 1 | 3 | 80 |
GO:0044267 | cellular protein metabolic process | 7.56e-02 | 1.00e+00 | 2.120 | 2 | 29 | 474 |
GO:0019083 | viral transcription | 7.59e-02 | 1.00e+00 | 3.669 | 1 | 10 | 81 |
GO:0044822 | poly(A) RNA binding | 7.77e-02 | 1.00e+00 | 1.549 | 3 | 49 | 1056 |
GO:0005681 | spliceosomal complex | 7.77e-02 | 1.00e+00 | 3.634 | 1 | 4 | 83 |
GO:0042802 | identical protein binding | 7.84e-02 | 1.00e+00 | 2.090 | 2 | 20 | 484 |
GO:0042593 | glucose homeostasis | 8.13e-02 | 1.00e+00 | 3.566 | 1 | 1 | 87 |
GO:0006979 | response to oxidative stress | 8.13e-02 | 1.00e+00 | 3.566 | 1 | 3 | 87 |
GO:0006415 | translational termination | 8.13e-02 | 1.00e+00 | 3.566 | 1 | 10 | 87 |
GO:0050821 | protein stabilization | 8.21e-02 | 1.00e+00 | 3.549 | 1 | 2 | 88 |
GO:0006629 | lipid metabolic process | 8.39e-02 | 1.00e+00 | 3.517 | 1 | 5 | 90 |
GO:0006928 | cellular component movement | 8.48e-02 | 1.00e+00 | 3.501 | 1 | 7 | 91 |
GO:0005200 | structural constituent of cytoskeleton | 8.48e-02 | 1.00e+00 | 3.501 | 1 | 8 | 91 |
GO:0001649 | osteoblast differentiation | 8.57e-02 | 1.00e+00 | 3.485 | 1 | 6 | 92 |
GO:0051091 | positive regulation of sequence-specific DNA binding transcription factor activity | 8.57e-02 | 1.00e+00 | 3.485 | 1 | 5 | 92 |
GO:0006414 | translational elongation | 8.66e-02 | 1.00e+00 | 3.470 | 1 | 13 | 93 |
GO:0051082 | unfolded protein binding | 8.66e-02 | 1.00e+00 | 3.470 | 1 | 5 | 93 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 9.64e-02 | 1.00e+00 | 3.308 | 1 | 10 | 104 |
GO:0014069 | postsynaptic density | 9.73e-02 | 1.00e+00 | 3.294 | 1 | 3 | 105 |
GO:0005506 | iron ion binding | 9.73e-02 | 1.00e+00 | 3.294 | 1 | 4 | 105 |
GO:0005741 | mitochondrial outer membrane | 9.73e-02 | 1.00e+00 | 3.294 | 1 | 7 | 105 |
GO:0030308 | negative regulation of cell growth | 1.02e-01 | 1.00e+00 | 3.227 | 1 | 6 | 110 |
GO:0015630 | microtubule cytoskeleton | 1.02e-01 | 1.00e+00 | 3.227 | 1 | 4 | 110 |
GO:0030529 | ribonucleoprotein complex | 1.03e-01 | 1.00e+00 | 3.201 | 1 | 8 | 112 |
GO:0072562 | blood microparticle | 1.03e-01 | 1.00e+00 | 3.214 | 1 | 3 | 111 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 1.05e-01 | 1.00e+00 | 3.176 | 1 | 11 | 114 |
GO:0019058 | viral life cycle | 1.06e-01 | 1.00e+00 | 3.163 | 1 | 13 | 115 |
GO:0044237 | cellular metabolic process | 1.08e-01 | 1.00e+00 | 3.138 | 1 | 5 | 117 |
GO:0006325 | chromatin organization | 1.09e-01 | 1.00e+00 | 3.126 | 1 | 5 | 118 |
GO:0045087 | innate immune response | 1.12e-01 | 1.00e+00 | 1.790 | 2 | 24 | 596 |
GO:0007050 | cell cycle arrest | 1.14e-01 | 1.00e+00 | 3.055 | 1 | 9 | 124 |
GO:0009615 | response to virus | 1.16e-01 | 1.00e+00 | 3.031 | 1 | 5 | 126 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 1.16e-01 | 1.00e+00 | 3.031 | 1 | 5 | 126 |
GO:0006413 | translational initiation | 1.20e-01 | 1.00e+00 | 2.975 | 1 | 17 | 131 |
GO:0003735 | structural constituent of ribosome | 1.25e-01 | 1.00e+00 | 2.911 | 1 | 10 | 137 |
GO:0007507 | heart development | 1.27e-01 | 1.00e+00 | 2.890 | 1 | 7 | 139 |
GO:0006457 | protein folding | 1.30e-01 | 1.00e+00 | 2.849 | 1 | 7 | 143 |
GO:0005737 | cytoplasm | 1.32e-01 | 1.00e+00 | 0.714 | 6 | 110 | 3767 |
GO:0051260 | protein homooligomerization | 1.32e-01 | 1.00e+00 | 2.829 | 1 | 2 | 145 |
GO:0061024 | membrane organization | 1.32e-01 | 1.00e+00 | 2.829 | 1 | 7 | 145 |
GO:0008017 | microtubule binding | 1.34e-01 | 1.00e+00 | 2.809 | 1 | 6 | 147 |
GO:0005769 | early endosome | 1.38e-01 | 1.00e+00 | 2.761 | 1 | 2 | 152 |
GO:0045121 | membrane raft | 1.41e-01 | 1.00e+00 | 2.723 | 1 | 8 | 156 |
GO:0000398 | mRNA splicing, via spliceosome | 1.48e-01 | 1.00e+00 | 2.651 | 1 | 8 | 164 |
GO:0030424 | axon | 1.50e-01 | 1.00e+00 | 2.634 | 1 | 4 | 166 |
GO:0044212 | transcription regulatory region DNA binding | 1.51e-01 | 1.00e+00 | 2.616 | 1 | 6 | 168 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 1.65e-01 | 1.00e+00 | 2.485 | 1 | 8 | 184 |
GO:0008380 | RNA splicing | 2.00e-01 | 1.00e+00 | 2.176 | 1 | 11 | 228 |
GO:0006412 | translation | 2.02e-01 | 1.00e+00 | 2.163 | 1 | 20 | 230 |
GO:0008152 | metabolic process | 2.23e-01 | 1.00e+00 | 1.998 | 1 | 3 | 258 |
GO:0000166 | nucleotide binding | 2.24e-01 | 1.00e+00 | 1.992 | 1 | 5 | 259 |
GO:0043065 | positive regulation of apoptotic process | 2.31e-01 | 1.00e+00 | 1.943 | 1 | 10 | 268 |
GO:0005615 | extracellular space | 2.37e-01 | 1.00e+00 | 1.106 | 2 | 17 | 957 |
GO:0005743 | mitochondrial inner membrane | 2.38e-01 | 1.00e+00 | 1.895 | 1 | 8 | 277 |
GO:0019899 | enzyme binding | 2.38e-01 | 1.00e+00 | 1.895 | 1 | 12 | 277 |
GO:0007186 | G-protein coupled receptor signaling pathway | 2.47e-01 | 1.00e+00 | 1.834 | 1 | 7 | 289 |
GO:0005856 | cytoskeleton | 2.48e-01 | 1.00e+00 | 1.824 | 1 | 12 | 291 |
GO:0005739 | mitochondrion | 2.52e-01 | 1.00e+00 | 1.046 | 2 | 28 | 998 |
GO:0019901 | protein kinase binding | 2.67e-01 | 1.00e+00 | 1.700 | 1 | 21 | 317 |
GO:0005813 | centrosome | 2.74e-01 | 1.00e+00 | 1.660 | 1 | 14 | 326 |
GO:0003682 | chromatin binding | 2.75e-01 | 1.00e+00 | 1.656 | 1 | 11 | 327 |
GO:0043565 | sequence-specific DNA binding | 2.88e-01 | 1.00e+00 | 1.574 | 1 | 6 | 346 |
GO:0005925 | focal adhesion | 3.02e-01 | 1.00e+00 | 1.493 | 1 | 19 | 366 |
GO:0007155 | cell adhesion | 3.04e-01 | 1.00e+00 | 1.481 | 1 | 6 | 369 |
GO:0006508 | proteolysis | 3.11e-01 | 1.00e+00 | 1.446 | 1 | 9 | 378 |
GO:0045892 | negative regulation of transcription, DNA-templated | 3.34e-01 | 1.00e+00 | 1.319 | 1 | 15 | 413 |
GO:0007596 | blood coagulation | 3.62e-01 | 1.00e+00 | 1.179 | 1 | 18 | 455 |
GO:0005524 | ATP binding | 3.63e-01 | 1.00e+00 | 0.667 | 2 | 60 | 1298 |
GO:0045893 | positive regulation of transcription, DNA-templated | 3.76e-01 | 1.00e+00 | 1.108 | 1 | 13 | 478 |
GO:0048471 | perinuclear region of cytoplasm | 3.91e-01 | 1.00e+00 | 1.037 | 1 | 13 | 502 |
GO:0005783 | endoplasmic reticulum | 4.23e-01 | 1.00e+00 | 0.890 | 1 | 10 | 556 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 4.32e-01 | 1.00e+00 | 0.854 | 1 | 16 | 570 |
GO:0005794 | Golgi apparatus | 4.54e-01 | 1.00e+00 | 0.756 | 1 | 15 | 610 |
GO:0005886 | plasma membrane | 4.71e-01 | 1.00e+00 | 0.259 | 3 | 45 | 2582 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 5.01e-01 | 1.00e+00 | 0.560 | 1 | 11 | 699 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 5.45e-01 | 1.00e+00 | 0.385 | 1 | 19 | 789 |
GO:0007165 | signal transduction | 5.97e-01 | 1.00e+00 | 0.184 | 1 | 24 | 907 |
GO:0008270 | zinc ion binding | 6.33e-01 | 1.00e+00 | 0.047 | 1 | 12 | 997 |
GO:0003677 | DNA binding | 7.09e-01 | 1.00e+00 | -0.242 | 1 | 28 | 1218 |
GO:0016021 | integral component of membrane | 8.74e-01 | 1.00e+00 | -0.944 | 1 | 27 | 1982 |