int-snw-5621

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
wolf-screen-ratio-mammosphere-adherent 0.958 2.11e-16 1.50e-03 2.78e-02
wolf-screen-ratio-mammosphere-adherent-int-snw-5621 subnetwork

Genes (14)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
ACO2 50 501.0001.076191Yes-
PSMA3 5684 120.5331.026218Yes-
PPARG 5468 1-0.5350.958131-Yes
PSMA2 5683 601.0931.10689Yes-
PSMD3 5709 570.9861.106146Yes-
HNRNPC 3183 201.8121.026119Yes-
PSMB7 5695 480.9821.05257Yes-
PSMA1 5682 610.9961.052123Yes-
PSMD11 5717 1211.0951.106183Yes-
ACTB 60 1671.1531.151587Yes-
HSPD1 3329 350.9131.035286Yes-
PSMD6 9861 110.8481.009131Yes-
RPSA 3921 1561.3271.151152Yes-
[ PRNP ] 5621 1-0.1350.95889--

Interactions (39)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMA2 5683 PSMA3 5684 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD;
int.HPRD: yeast 2-hybrid
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
PSMA3 5684 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA3 5684 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
PSMB7 5695 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct
PSMD11 5717 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, INTEROLOG
PSMA1 5682 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastMedium
PPARG 5468 PRNP 5621 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
HSPD1 3329 PSMA3 5684 pp -- int.I2D: BioGrid
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
ACO2 50 PSMD11 5717 pp -- int.I2D: YeastLow
HSPD1 3329 RPSA 3921 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
PSMA2 5683 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow, BioGrid
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
PRNP 5621 PSMD6 9861 pp -- int.I2D: MINT_Mouse
PSMA1 5682 PSMA3 5684 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd;
int.HPRD: in vitro
PSMA3 5684 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
ACO2 50 HSPD1 3329 pp -- int.I2D: IntAct_Yeast
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PRNP 5621 PSMA3 5684 pp -- int.Intact: MI:0915(physical association);
int.I2D: HPRD, MINT, IntAct;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
HNRNPC 3183 PSMA3 5684 pp -- int.I2D: BioGrid
ACTB 60 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast
PSMD3 5709 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Yeast, MINT_Worm, MINT_Yeast, YeastHigh, BioGrid, BIND_Yeast, IntAct_Worm, INTEROLOG, Krogan_Core, MIPS
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
ACTB 60 HSPD1 3329 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastLow
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core
HSPD1 3329 PRNP 5621 pp -- int.I2D: BIND, HPRD, BCI;
int.HPRD: in vitro, in vivo
ACTB 60 PSMA3 5684 pp -- int.I2D: BioGrid, BioGrid_Yeast

Related GO terms (280)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0006521regulation of cellular amino acid metabolic process1.31e-141.89e-107.17271750
GO:0000502proteasome complex3.93e-145.66e-106.95871758
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest8.09e-141.17e-096.81671964
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle9.06e-141.31e-096.79472265
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.56e-132.25e-096.68772270
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent1.91e-132.76e-096.64672072
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.33e-133.37e-096.60772274
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I2.57e-133.71e-096.58772075
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process3.75e-135.41e-096.51272379
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.13e-121.63e-086.29372192
GO:0000209protein polyubiquitination5.94e-128.57e-085.958720116
GO:0016071mRNA metabolic process7.99e-121.15e-075.208831223
GO:0016070RNA metabolic process1.82e-112.62e-075.060832247
GO:0043066negative regulation of apoptotic process2.65e-113.82e-074.451931424
GO:0000082G1/S transition of mitotic cell cycle3.52e-115.08e-075.597732149
GO:0010467gene expression3.65e-115.27e-073.9451059669
GO:0042981regulation of apoptotic process3.69e-115.32e-075.587724150
GO:0034641cellular nitrogen compound metabolic process9.32e-111.34e-065.398720171
GO:0016032viral process2.08e-102.99e-064.118955534
GO:0005839proteasome core complex1.69e-092.43e-057.8394818
GO:0004298threonine-type endopeptidase activity2.13e-093.08e-057.7614819
GO:0005654nucleoplasm4.11e-095.93e-053.25110761082
GO:0070062extracellular vesicular exosome2.88e-084.15e-042.365121042400
GO:0000278mitotic cell cycle2.97e-084.29e-044.205748391
GO:0019773proteasome core complex, alpha-subunit complex4.07e-085.86e-048.594348
GO:0005829cytosol4.54e-086.55e-042.308121322496
GO:0006915apoptotic process3.26e-074.71e-033.700733555
GO:0022624proteasome accessory complex4.91e-077.08e-037.5063817
GO:0044281small molecule metabolic process4.58e-066.60e-022.7678581211
GO:0005838proteasome regulatory particle5.74e-058.28e-017.4242712
GO:0043044ATP-dependent chromatin remodeling2.19e-041.00e+006.4852423
GO:0031492nucleosomal DNA binding3.03e-041.00e+006.2542427
GO:0005634nucleus4.09e-041.00e+001.314111364559
GO:2000230negative regulation of pancreatic stellate cell proliferation9.71e-041.00e+0010.009111
GO:0002842positive regulation of T cell mediated immune response to tumor cell9.71e-041.00e+0010.009111
GO:0004955prostaglandin receptor activity9.71e-041.00e+0010.009111
GO:0048291isotype switching to IgG isotypes9.71e-041.00e+0010.009111
GO:0060694regulation of cholesterol transporter activity9.71e-041.00e+0010.009111
GO:0045713low-density lipoprotein particle receptor biosynthetic process9.71e-041.00e+0010.009111
GO:1901558response to metformin9.71e-041.00e+0010.009111
GO:0036270response to diuretic9.71e-041.00e+0010.009111
GO:0002368B cell cytokine production9.71e-041.00e+0010.009111
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding1.17e-031.00e+005.2812553
GO:0051087chaperone binding1.45e-031.00e+005.1262659
GO:00515383 iron, 4 sulfur cluster binding1.94e-031.00e+009.009112
GO:0071306cellular response to vitamin E1.94e-031.00e+009.009112
GO:0003994aconitate hydratase activity1.94e-031.00e+009.009112
GO:0006407rRNA export from nucleus1.94e-031.00e+009.009112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)1.94e-031.00e+009.009112
GO:0005055laminin receptor activity1.94e-031.00e+009.009112
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process2.46e-031.00e+004.7422777
GO:0043234protein complex2.61e-031.00e+003.389318295
GO:0055098response to low-density lipoprotein particle2.91e-031.00e+008.424113
GO:0001012RNA polymerase II regulatory region DNA binding2.91e-031.00e+008.424113
GO:0010871negative regulation of receptor biosynthetic process2.91e-031.00e+008.424113
GO:0046321positive regulation of fatty acid oxidation2.91e-031.00e+008.424113
GO:0006458'de novo' protein folding2.91e-031.00e+008.424113
GO:0030135coated vesicle2.91e-031.00e+008.424113
GO:0016020membrane3.25e-031.00e+001.8796901681
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)3.88e-031.00e+008.009114
GO:003068690S preribosome3.88e-031.00e+008.009114
GO:0070885negative regulation of calcineurin-NFAT signaling cascade3.88e-031.00e+008.009114
GO:0035357peroxisome proliferator activated receptor signaling pathway3.88e-031.00e+008.009114
GO:0060100positive regulation of phagocytosis, engulfment4.84e-031.00e+007.687115
GO:0032966negative regulation of collagen biosynthetic process4.84e-031.00e+007.687115
GO:0010891negative regulation of sequestering of triglyceride4.84e-031.00e+007.687115
GO:0043248proteasome assembly4.84e-031.00e+007.687115
GO:0046696lipopolysaccharide receptor complex4.84e-031.00e+007.687115
GO:0050544arachidonic acid binding4.84e-031.00e+007.687115
GO:0060336negative regulation of interferon-gamma-mediated signaling pathway4.84e-031.00e+007.687115
GO:0006102isocitrate metabolic process4.84e-031.00e+007.687115
GO:0060850regulation of transcription involved in cell fate commitment4.84e-031.00e+007.687115
GO:0005515protein binding5.80e-031.00e+000.912111846024
GO:0003688DNA replication origin binding5.81e-031.00e+007.424126
GO:1901379regulation of potassium ion transmembrane transport5.81e-031.00e+007.424116
GO:0006101citrate metabolic process5.81e-031.00e+007.424116
GO:0033993response to lipid5.81e-031.00e+007.424126
GO:0030957Tat protein binding5.81e-031.00e+007.424136
GO:0019907cyclin-dependent protein kinase activating kinase holoenzyme complex5.81e-031.00e+007.424116
GO:0010887negative regulation of cholesterol storage5.81e-031.00e+007.424116
GO:0046007negative regulation of activated T cell proliferation5.81e-031.00e+007.424116
GO:0000790nuclear chromatin6.73e-031.00e+003.99829129
GO:0000028ribosomal small subunit assembly6.78e-031.00e+007.201117
GO:0043008ATP-dependent protein binding6.78e-031.00e+007.201117
GO:0002674negative regulation of acute inflammatory response6.78e-031.00e+007.201117
GO:0071455cellular response to hyperoxia6.78e-031.00e+007.201117
GO:0015909long-chain fatty acid transport6.78e-031.00e+007.201117
GO:0051974negative regulation of telomerase activity7.74e-031.00e+007.009128
GO:0070688MLL5-L complex7.74e-031.00e+007.009118
GO:0051604protein maturation7.74e-031.00e+007.009118
GO:0016887ATPase activity7.89e-031.00e+003.87927140
GO:0031000response to caffeine8.70e-031.00e+006.839129
GO:0071380cellular response to prostaglandin E stimulus8.70e-031.00e+006.839119
GO:0032703negative regulation of interleukin-2 production9.67e-031.00e+006.6871110
GO:0043032positive regulation of macrophage activation9.67e-031.00e+006.6871110
GO:0050872white fat cell differentiation9.67e-031.00e+006.6871110
GO:0032700negative regulation of interleukin-17 production9.67e-031.00e+006.6871110
GO:0032727positive regulation of interferon-alpha production1.06e-021.00e+006.5491111
GO:0019395fatty acid oxidation1.06e-021.00e+006.5491111
GO:0048714positive regulation of oligodendrocyte differentiation1.06e-021.00e+006.5491211
GO:0045120pronucleus1.06e-021.00e+006.5491211
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding1.08e-021.00e+003.64227165
GO:0006878cellular copper ion homeostasis1.16e-021.00e+006.4241112
GO:00709353'-UTR-mediated mRNA stabilization1.16e-021.00e+006.4241212
GO:0042953lipoprotein transport1.16e-021.00e+006.4241112
GO:0046688response to copper ion1.26e-021.00e+006.3081113
GO:0010745negative regulation of macrophage derived foam cell differentiation1.26e-021.00e+006.3081213
GO:0050860negative regulation of T cell receptor signaling pathway1.26e-021.00e+006.3081113
GO:0030234enzyme regulator activity1.26e-021.00e+006.3081313
GO:0001530lipopolysaccharide binding1.26e-021.00e+006.3081313
GO:0008266poly(U) RNA binding1.26e-021.00e+006.3081113
GO:0051131chaperone-mediated protein complex assembly1.26e-021.00e+006.3081113
GO:0033189response to vitamin A1.35e-021.00e+006.2011114
GO:0035267NuA4 histone acetyltransferase complex1.35e-021.00e+006.2011414
GO:0071285cellular response to lithium ion1.35e-021.00e+006.2011214
GO:0042026protein refolding1.45e-021.00e+006.1021215
GO:0046965retinoid X receptor binding1.45e-021.00e+006.1021115
GO:0042176regulation of protein catabolic process1.54e-021.00e+006.0091316
GO:0050998nitric-oxide synthase binding1.54e-021.00e+006.0091116
GO:0030224monocyte differentiation1.54e-021.00e+006.0091116
GO:0035902response to immobilization stress1.64e-021.00e+005.9211117
GO:0050870positive regulation of T cell activation1.64e-021.00e+005.9211117
GO:0055088lipid homeostasis1.73e-021.00e+005.8391118
GO:0033613activating transcription factor binding1.73e-021.00e+005.8391118
GO:0048863stem cell differentiation1.83e-021.00e+005.7611119
GO:0032733positive regulation of interleukin-10 production1.83e-021.00e+005.7611119
GO:0005759mitochondrial matrix2.00e-021.00e+003.176214228
GO:0042100B cell proliferation2.02e-021.00e+005.6161121
GO:0046686response to cadmium ion2.12e-021.00e+005.5491222
GO:0030863cortical cytoskeleton2.12e-021.00e+005.5491122
GO:0036464cytoplasmic ribonucleoprotein granule2.12e-021.00e+005.5491422
GO:0043236laminin binding2.21e-021.00e+005.4851123
GO:0005844polysome2.21e-021.00e+005.4851423
GO:0032689negative regulation of interferon-gamma production2.31e-021.00e+005.4241124
GO:0042113B cell activation2.40e-021.00e+005.3651225
GO:0032735positive regulation of interleukin-12 production2.40e-021.00e+005.3651125
GO:0009409response to cold2.50e-021.00e+005.3081226
GO:0003730mRNA 3'-UTR binding2.50e-021.00e+005.3081226
GO:0015631tubulin binding2.59e-021.00e+005.2541127
GO:0030331estrogen receptor binding2.59e-021.00e+005.2541227
GO:0043022ribosome binding2.59e-021.00e+005.2541327
GO:0006099tricarboxylic acid cycle2.69e-021.00e+005.2011428
GO:0048662negative regulation of smooth muscle cell proliferation2.69e-021.00e+005.2011128
GO:0019894kinesin binding2.69e-021.00e+005.2011128
GO:0050873brown fat cell differentiation2.78e-021.00e+005.1511229
GO:0042594response to starvation2.97e-021.00e+005.0551131
GO:0001890placenta development2.97e-021.00e+005.0551131
GO:0045600positive regulation of fat cell differentiation3.06e-021.00e+005.0091132
GO:0006200ATP catabolic process3.17e-021.00e+002.819215292
GO:0007611learning or memory3.25e-021.00e+004.9211234
GO:0001895retina homeostasis3.25e-021.00e+004.9211134
GO:00515394 iron, 4 sulfur cluster binding3.35e-021.00e+004.8791335
GO:0034332adherens junction organization3.44e-021.00e+004.8391136
GO:0001933negative regulation of protein phosphorylation3.44e-021.00e+004.8391236
GO:0004879ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity3.44e-021.00e+004.8391136
GO:0032755positive regulation of interleukin-6 production3.44e-021.00e+004.8391236
GO:0051084'de novo' posttranslational protein folding3.53e-021.00e+004.7991437
GO:0001228RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription3.53e-021.00e+004.7991237
GO:0032880regulation of protein localization3.53e-021.00e+004.7991137
GO:0048469cell maturation3.63e-021.00e+004.7611138
GO:0070527platelet aggregation3.63e-021.00e+004.7611238
GO:0032729positive regulation of interferon-gamma production3.72e-021.00e+004.7231239
GO:0022627cytosolic small ribosomal subunit3.72e-021.00e+004.7231439
GO:0007411axon guidance3.72e-021.00e+002.691213319
GO:0042110T cell activation4.00e-021.00e+004.6161342
GO:0019898extrinsic component of membrane4.00e-021.00e+004.6161142
GO:0030374ligand-dependent nuclear receptor transcription coactivator activity4.10e-021.00e+004.5821143
GO:0021762substantia nigra development4.19e-021.00e+004.5491244
GO:0045165cell fate commitment4.19e-021.00e+004.5491144
GO:0003723RNA binding4.23e-021.00e+002.591220342
GO:0003707steroid hormone receptor activity4.28e-021.00e+004.5171145
GO:0032526response to retinoic acid4.38e-021.00e+004.4851246
GO:0005507copper ion binding4.38e-021.00e+004.4851246
GO:0006091generation of precursor metabolites and energy4.75e-021.00e+004.3651350
GO:0006986response to unfolded protein4.75e-021.00e+004.3651250
GO:0031100organ regeneration4.75e-021.00e+004.3651450
GO:0005905coated pit4.75e-021.00e+004.3651350
GO:0009612response to mechanical stimulus4.75e-021.00e+004.3651250
GO:0043401steroid hormone mediated signaling pathway4.84e-021.00e+004.3361151
GO:0003725double-stranded RNA binding4.93e-021.00e+004.3081552
GO:0045216cell-cell junction organization5.12e-021.00e+004.2541254
GO:0000932cytoplasmic mRNA processing body5.12e-021.00e+004.2541354
GO:0002039p53 binding5.21e-021.00e+004.2271755
GO:0071300cellular response to retinoic acid5.21e-021.00e+004.2271255
GO:0043627response to estrogen5.30e-021.00e+004.2011256
GO:0008217regulation of blood pressure5.40e-021.00e+004.1761457
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity5.58e-021.00e+004.1261259
GO:0009986cell surface5.65e-021.00e+002.358211402
GO:0030855epithelial cell differentiation5.76e-021.00e+004.0781461
GO:0019903protein phosphatase binding5.86e-021.00e+004.0551462
GO:0030141secretory granule5.86e-021.00e+004.0551262
GO:0008144drug binding5.95e-021.00e+004.0311163
GO:0032869cellular response to insulin stimulus5.95e-021.00e+004.0311363
GO:0003697single-stranded DNA binding6.40e-021.00e+003.9211568
GO:0034329cell junction assembly6.40e-021.00e+003.9211168
GO:0005730nucleolus6.58e-021.00e+001.3284691641
GO:0007584response to nutrient6.68e-021.00e+003.8591471
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis6.95e-021.00e+003.7991674
GO:0071013catalytic step 2 spliceosome7.31e-021.00e+003.7231478
GO:0031225anchored component of membrane7.31e-021.00e+003.7231178
GO:0002755MyD88-dependent toll-like receptor signaling pathway7.49e-021.00e+003.6871380
GO:0044267cellular protein metabolic process7.56e-021.00e+002.120229474
GO:0019083viral transcription7.59e-021.00e+003.66911081
GO:0044822poly(A) RNA binding7.77e-021.00e+001.5493491056
GO:0005681spliceosomal complex7.77e-021.00e+003.6341483
GO:0042802identical protein binding7.84e-021.00e+002.090220484
GO:0042593glucose homeostasis8.13e-021.00e+003.5661187
GO:0006979response to oxidative stress8.13e-021.00e+003.5661387
GO:0006415translational termination8.13e-021.00e+003.56611087
GO:0050821protein stabilization8.21e-021.00e+003.5491288
GO:0006629lipid metabolic process8.39e-021.00e+003.5171590
GO:0006928cellular component movement8.48e-021.00e+003.5011791
GO:0005200structural constituent of cytoskeleton8.48e-021.00e+003.5011891
GO:0001649osteoblast differentiation8.57e-021.00e+003.4851692
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activity8.57e-021.00e+003.4851592
GO:0006414translational elongation8.66e-021.00e+003.47011393
GO:0051082unfolded protein binding8.66e-021.00e+003.4701593
GO:0006614SRP-dependent cotranslational protein targeting to membrane9.64e-021.00e+003.308110104
GO:0014069postsynaptic density9.73e-021.00e+003.29413105
GO:0005506iron ion binding9.73e-021.00e+003.29414105
GO:0005741mitochondrial outer membrane9.73e-021.00e+003.29417105
GO:0030308negative regulation of cell growth1.02e-011.00e+003.22716110
GO:0015630microtubule cytoskeleton1.02e-011.00e+003.22714110
GO:0030529ribonucleoprotein complex1.03e-011.00e+003.20118112
GO:0072562blood microparticle1.03e-011.00e+003.21413111
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.05e-011.00e+003.176111114
GO:0019058viral life cycle1.06e-011.00e+003.163113115
GO:0044237cellular metabolic process1.08e-011.00e+003.13815117
GO:0006325chromatin organization1.09e-011.00e+003.12615118
GO:0045087innate immune response1.12e-011.00e+001.790224596
GO:0007050cell cycle arrest1.14e-011.00e+003.05519124
GO:0009615response to virus1.16e-011.00e+003.03115126
GO:0006511ubiquitin-dependent protein catabolic process1.16e-011.00e+003.03115126
GO:0006413translational initiation1.20e-011.00e+002.975117131
GO:0003735structural constituent of ribosome1.25e-011.00e+002.911110137
GO:0007507heart development1.27e-011.00e+002.89017139
GO:0006457protein folding1.30e-011.00e+002.84917143
GO:0005737cytoplasm1.32e-011.00e+000.71461103767
GO:0051260protein homooligomerization1.32e-011.00e+002.82912145
GO:0061024membrane organization1.32e-011.00e+002.82917145
GO:0008017microtubule binding1.34e-011.00e+002.80916147
GO:0005769early endosome1.38e-011.00e+002.76112152
GO:0045121membrane raft1.41e-011.00e+002.72318156
GO:0000398mRNA splicing, via spliceosome1.48e-011.00e+002.65118164
GO:0030424axon1.50e-011.00e+002.63414166
GO:0044212transcription regulatory region DNA binding1.51e-011.00e+002.61616168
GO:0006367transcription initiation from RNA polymerase II promoter1.65e-011.00e+002.48518184
GO:0008380RNA splicing2.00e-011.00e+002.176111228
GO:0006412translation2.02e-011.00e+002.163120230
GO:0008152metabolic process2.23e-011.00e+001.99813258
GO:0000166nucleotide binding2.24e-011.00e+001.99215259
GO:0043065positive regulation of apoptotic process2.31e-011.00e+001.943110268
GO:0005615extracellular space2.37e-011.00e+001.106217957
GO:0005743mitochondrial inner membrane2.38e-011.00e+001.89518277
GO:0019899enzyme binding2.38e-011.00e+001.895112277
GO:0007186G-protein coupled receptor signaling pathway2.47e-011.00e+001.83417289
GO:0005856cytoskeleton2.48e-011.00e+001.824112291
GO:0005739mitochondrion2.52e-011.00e+001.046228998
GO:0019901protein kinase binding2.67e-011.00e+001.700121317
GO:0005813centrosome2.74e-011.00e+001.660114326
GO:0003682chromatin binding2.75e-011.00e+001.656111327
GO:0043565sequence-specific DNA binding2.88e-011.00e+001.57416346
GO:0005925focal adhesion3.02e-011.00e+001.493119366
GO:0007155cell adhesion3.04e-011.00e+001.48116369
GO:0006508proteolysis3.11e-011.00e+001.44619378
GO:0045892negative regulation of transcription, DNA-templated3.34e-011.00e+001.319115413
GO:0007596blood coagulation3.62e-011.00e+001.179118455
GO:0005524ATP binding3.63e-011.00e+000.6672601298
GO:0045893positive regulation of transcription, DNA-templated3.76e-011.00e+001.108113478
GO:0048471perinuclear region of cytoplasm3.91e-011.00e+001.037113502
GO:0005783endoplasmic reticulum4.23e-011.00e+000.890110556
GO:0000122negative regulation of transcription from RNA polymerase II promoter4.32e-011.00e+000.854116570
GO:0005794Golgi apparatus4.54e-011.00e+000.756115610
GO:0005886plasma membrane4.71e-011.00e+000.2593452582
GO:0003700sequence-specific DNA binding transcription factor activity5.01e-011.00e+000.560111699
GO:0045944positive regulation of transcription from RNA polymerase II promoter5.45e-011.00e+000.385119789
GO:0007165signal transduction5.97e-011.00e+000.184124907
GO:0008270zinc ion binding6.33e-011.00e+000.047112997
GO:0003677DNA binding7.09e-011.00e+00-0.2421281218
GO:0016021integral component of membrane8.74e-011.00e+00-0.9441271982