Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
wolf-screen-ratio-mammosphere-adherent | 0.932 | 2.16e-15 | 2.65e-03 | 4.21e-02 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
CAD | 790 | 17 | 0.807 | 1.007 | 333 | - | - |
RSL24D1 | 51187 | 36 | 1.300 | 1.020 | 59 | Yes | - |
EIF2S2 | 8894 | 27 | 1.075 | 1.138 | 81 | Yes | - |
PSMA2 | 5683 | 60 | 1.093 | 1.106 | 89 | Yes | - |
PPP2R1A | 5518 | 9 | 0.644 | 0.985 | 249 | Yes | - |
CLTC | 1213 | 35 | 0.884 | 1.138 | 247 | Yes | - |
ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
HSPD1 | 3329 | 35 | 0.913 | 1.035 | 286 | Yes | - |
[ PRKACA ] | 5566 | 1 | -0.109 | 0.932 | 206 | Yes | - |
RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - |
CFL1 | 1072 | 12 | 0.674 | 1.020 | 203 | Yes | - |
PGD | 5226 | 75 | 1.201 | 1.106 | 138 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
PPP2R1A | 5518 | PRKACA | 5566 | pp | -- | int.I2D: IntAct_Mouse |
CAD | 790 | RPSA | 3921 | pp | -- | int.I2D: IntAct_Yeast |
PPP2R1A | 5518 | PSMA2 | 5683 | pp | -- | int.I2D: IntAct_Mouse |
CLTC | 1213 | PRKACA | 5566 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid, SOURAV_MAPK_HIGH, IntAct |
PGD | 5226 | PPP2R1A | 5518 | pp | -- | int.I2D: YeastLow |
HSPD1 | 3329 | PRKACA | 5566 | pp | -- | int.I2D: BCI, HPRD; int.HPRD: in vitro |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
CAD | 790 | PRKACA | 5566 | pp | -- | int.I2D: HPRD, BCI; int.HPRD: in vitro |
ACTB | 60 | CLTC | 1213 | pp | -- | int.I2D: IntAct_Yeast |
CFL1 | 1072 | RSL24D1 | 51187 | pp | -- | int.I2D: YeastLow |
CLTC | 1213 | EIF2S2 | 8894 | pp | -- | int.I2D: YeastLow |
ACTB | 60 | CFL1 | 1072 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, MINT_Yeast, MIPS, BioGrid, BIND_Yeast, HPRD, IntAct, IntAct_Yeast, MINT, VidalHuman_core, YeastLow, Yu_GoldStd; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid |
ACTB | 60 | PPP2R1A | 5518 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | CAD | 790 | pp | -- | int.I2D: IntAct_Yeast |
HSPD1 | 3329 | RPSA | 3921 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
CFL1 | 1072 | PRKACA | 5566 | pp | -- | int.I2D: MINT; int.Mint: MI:0217(phosphorylation reaction) |
CFL1 | 1072 | PGD | 5226 | pp | -- | int.I2D: YeastLow |
HSPD1 | 3329 | PPP2R1A | 5518 | pp | -- | int.Intact: MI:0914(association); int.I2D: HPRD, IntAct; int.HPRD: in vivo |
ACTB | 60 | HSPD1 | 3329 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastLow |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0070062 | extracellular vesicular exosome | 7.63e-07 | 1.10e-02 | 2.324 | 10 | 104 | 2400 |
GO:0005829 | cytosol | 1.11e-06 | 1.61e-02 | 2.268 | 10 | 132 | 2496 |
GO:0016020 | membrane | 1.08e-05 | 1.55e-01 | 2.516 | 8 | 90 | 1681 |
GO:0043234 | protein complex | 7.46e-05 | 1.00e+00 | 4.027 | 4 | 18 | 295 |
GO:0018107 | peptidyl-threonine phosphorylation | 4.16e-04 | 1.00e+00 | 6.022 | 2 | 4 | 37 |
GO:0016071 | mRNA metabolic process | 7.24e-04 | 1.00e+00 | 4.015 | 3 | 31 | 223 |
GO:0003725 | double-stranded RNA binding | 8.22e-04 | 1.00e+00 | 5.531 | 2 | 5 | 52 |
GO:0002842 | positive regulation of T cell mediated immune response to tumor cell | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:0048291 | isotype switching to IgG isotypes | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:0004088 | carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:0070335 | aspartate binding | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:0070262 | peptidyl-serine dephosphorylation | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:0004151 | dihydroorotase activity | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:0019521 | D-gluconate metabolic process | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:0004070 | aspartate carbamoyltransferase activity | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:0002368 | B cell cytokine production | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:0016070 | RNA metabolic process | 9.74e-04 | 1.00e+00 | 3.868 | 3 | 32 | 247 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 1.66e-03 | 1.00e+00 | 5.022 | 2 | 6 | 74 |
GO:0002176 | male germ cell proliferation | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0019322 | pentose biosynthetic process | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 2 | 2 |
GO:0005055 | laminin receptor activity | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0070409 | carbamoyl phosphate biosynthetic process | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0010467 | gene expression | 1.68e-03 | 1.00e+00 | 2.845 | 4 | 59 | 669 |
GO:0019901 | protein kinase binding | 2.00e-03 | 1.00e+00 | 3.508 | 3 | 21 | 317 |
GO:0016363 | nuclear matrix | 2.49e-03 | 1.00e+00 | 4.723 | 2 | 12 | 91 |
GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 3 |
GO:0005850 | eukaryotic translation initiation factor 2 complex | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 3 |
GO:0001842 | neural fold formation | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 3 |
GO:1900126 | negative regulation of hyaluronan biosynthetic process | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 2 | 3 |
GO:0006458 | 'de novo' protein folding | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 3 |
GO:0009051 | pentose-phosphate shunt, oxidative branch | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 2 | 3 |
GO:0030135 | coated vesicle | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 3 |
GO:0044205 | 'de novo' UMP biosynthetic process | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 3 |
GO:0006207 | 'de novo' pyrimidine nucleobase biosynthetic process | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 3 |
GO:0071439 | clathrin complex | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 2 | 3 |
GO:0005925 | focal adhesion | 3.01e-03 | 1.00e+00 | 3.300 | 3 | 19 | 366 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0071374 | cellular response to parathyroid hormone stimulus | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0032051 | clathrin light chain binding | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0006543 | glutamine catabolic process | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:1903077 | negative regulation of protein localization to plasma membrane | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0000278 | mitotic cell cycle | 3.62e-03 | 1.00e+00 | 3.205 | 3 | 48 | 391 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 3.88e-03 | 1.00e+00 | 4.398 | 2 | 11 | 114 |
GO:0051414 | response to cortisol | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0019932 | second-messenger-mediated signaling | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0042518 | negative regulation of tyrosine phosphorylation of Stat3 protein | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0046696 | lipopolysaccharide receptor complex | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0043066 | negative regulation of apoptotic process | 4.55e-03 | 1.00e+00 | 3.088 | 3 | 31 | 424 |
GO:0009615 | response to virus | 4.72e-03 | 1.00e+00 | 4.254 | 2 | 5 | 126 |
GO:0003688 | DNA replication origin binding | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 2 | 6 |
GO:0030130 | clathrin coat of trans-Golgi network vesicle | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 3 | 6 |
GO:0030118 | clathrin coat | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 2 | 6 |
GO:0030957 | Tat protein binding | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 3 | 6 |
GO:0046134 | pyrimidine nucleoside biosynthetic process | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 6 |
GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 6 |
GO:0030836 | positive regulation of actin filament depolymerization | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 2 | 6 |
GO:0006413 | translational initiation | 5.09e-03 | 1.00e+00 | 4.198 | 2 | 17 | 131 |
GO:0031982 | vesicle | 5.09e-03 | 1.00e+00 | 4.198 | 2 | 9 | 131 |
GO:0000086 | G2/M transition of mitotic cell cycle | 5.48e-03 | 1.00e+00 | 4.144 | 2 | 9 | 136 |
GO:0007596 | blood coagulation | 5.55e-03 | 1.00e+00 | 2.986 | 3 | 18 | 455 |
GO:0004691 | cAMP-dependent protein kinase activity | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 1 | 7 |
GO:0000028 | ribosomal small subunit assembly | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 1 | 7 |
GO:0030132 | clathrin coat of coated pit | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 2 | 7 |
GO:0061024 | membrane organization | 6.20e-03 | 1.00e+00 | 4.051 | 2 | 7 | 145 |
GO:0044267 | cellular protein metabolic process | 6.22e-03 | 1.00e+00 | 2.927 | 3 | 29 | 474 |
GO:0070613 | regulation of protein processing | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 8 |
GO:0070688 | MLL5-L complex | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 8 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 4 | 8 |
GO:0097546 | ciliary base | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 8 |
GO:0097225 | sperm midpiece | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 8 |
GO:0030042 | actin filament depolymerization | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 2 | 8 |
GO:0051604 | protein maturation | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 8 |
GO:0008543 | fibroblast growth factor receptor signaling pathway | 7.15e-03 | 1.00e+00 | 3.946 | 2 | 9 | 156 |
GO:0046777 | protein autophosphorylation | 7.32e-03 | 1.00e+00 | 3.927 | 2 | 7 | 158 |
GO:0045667 | regulation of osteoblast differentiation | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 9 |
GO:0031588 | AMP-activated protein kinase complex | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 9 |
GO:0014075 | response to amine | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 9 |
GO:2000810 | regulation of tight junction assembly | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 2 | 9 |
GO:0006228 | UTP biosynthetic process | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 9 |
GO:0005952 | cAMP-dependent protein kinase complex | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 9 |
GO:0048240 | sperm capacitation | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 9 |
GO:0031000 | response to caffeine | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 2 | 9 |
GO:0006098 | pentose-phosphate shunt | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 4 | 10 |
GO:0050804 | regulation of synaptic transmission | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 10 |
GO:0034237 | protein kinase A regulatory subunit binding | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 10 |
GO:0043032 | positive regulation of macrophage activation | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 10 |
GO:0071872 | cellular response to epinephrine stimulus | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 10 |
GO:0007084 | mitotic nuclear envelope reassembly | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 10 |
GO:0016032 | viral process | 8.65e-03 | 1.00e+00 | 2.755 | 3 | 55 | 534 |
GO:0044822 | poly(A) RNA binding | 8.79e-03 | 1.00e+00 | 2.187 | 4 | 49 | 1056 |
GO:0032727 | positive regulation of interferon-alpha production | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 1 | 11 |
GO:0061001 | regulation of dendritic spine morphogenesis | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 2 | 11 |
GO:0061136 | regulation of proteasomal protein catabolic process | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 2 | 12 |
GO:0006275 | regulation of DNA replication | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 2 | 12 |
GO:0086064 | cell communication by electrical coupling involved in cardiac conduction | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 2 | 12 |
GO:0030111 | regulation of Wnt signaling pathway | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 12 |
GO:0060314 | regulation of ryanodine-sensitive calcium-release channel activity | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 12 |
GO:0035584 | calcium-mediated signaling using intracellular calcium source | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 12 |
GO:0006672 | ceramide metabolic process | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 1 | 13 |
GO:0001530 | lipopolysaccharide binding | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 3 | 13 |
GO:0046827 | positive regulation of protein export from nucleus | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 3 | 13 |
GO:0051131 | chaperone-mediated protein complex assembly | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 1 | 13 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 4 | 14 |
GO:0045087 | innate immune response | 1.17e-02 | 1.00e+00 | 2.597 | 3 | 24 | 596 |
GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 2 | 15 |
GO:0055117 | regulation of cardiac muscle contraction | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 15 |
GO:0042026 | protein refolding | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 2 | 15 |
GO:0034199 | activation of protein kinase A activity | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 15 |
GO:0031258 | lamellipodium membrane | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 2 | 16 |
GO:0050998 | nitric-oxide synthase binding | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 1 | 16 |
GO:0022604 | regulation of cell morphogenesis | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 1 | 16 |
GO:0006541 | glutamine metabolic process | 1.41e-02 | 1.00e+00 | 6.144 | 1 | 1 | 17 |
GO:0050870 | positive regulation of T cell activation | 1.41e-02 | 1.00e+00 | 6.144 | 1 | 1 | 17 |
GO:0044281 | small molecule metabolic process | 1.42e-02 | 1.00e+00 | 1.989 | 4 | 58 | 1211 |
GO:0005839 | proteasome core complex | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 8 | 18 |
GO:0051480 | cytosolic calcium ion homeostasis | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 18 |
GO:0017144 | drug metabolic process | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 18 |
GO:0006412 | translation | 1.50e-02 | 1.00e+00 | 3.386 | 2 | 20 | 230 |
GO:0019433 | triglyceride catabolic process | 1.57e-02 | 1.00e+00 | 5.983 | 1 | 1 | 19 |
GO:0004298 | threonine-type endopeptidase activity | 1.57e-02 | 1.00e+00 | 5.983 | 1 | 8 | 19 |
GO:0071158 | positive regulation of cell cycle arrest | 1.57e-02 | 1.00e+00 | 5.983 | 1 | 2 | 19 |
GO:0032733 | positive regulation of interleukin-10 production | 1.57e-02 | 1.00e+00 | 5.983 | 1 | 1 | 19 |
GO:0010881 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion | 1.57e-02 | 1.00e+00 | 5.983 | 1 | 1 | 19 |
GO:0008601 | protein phosphatase type 2A regulator activity | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 2 | 20 |
GO:0000159 | protein phosphatase type 2A complex | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 2 | 20 |
GO:0043393 | regulation of protein binding | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 20 |
GO:0042100 | B cell proliferation | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 21 |
GO:0030010 | establishment of cell polarity | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 2 | 21 |
GO:0045595 | regulation of cell differentiation | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 21 |
GO:0071364 | cellular response to epidermal growth factor stimulus | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 21 |
GO:0000281 | mitotic cytokinesis | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 21 |
GO:0005524 | ATP binding | 1.79e-02 | 1.00e+00 | 1.889 | 4 | 60 | 1298 |
GO:0005975 | carbohydrate metabolic process | 1.80e-02 | 1.00e+00 | 3.248 | 2 | 9 | 253 |
GO:0003823 | antigen binding | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 1 | 22 |
GO:0034704 | calcium channel complex | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 1 | 22 |
GO:0006206 | pyrimidine nucleobase metabolic process | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 2 | 22 |
GO:0033574 | response to testosterone | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 2 | 22 |
GO:0030863 | cortical cytoskeleton | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 4 | 22 |
GO:0030864 | cortical actin cytoskeleton | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 1 | 23 |
GO:0043236 | laminin binding | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 1 | 23 |
GO:0043200 | response to amino acid | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 1 | 23 |
GO:0043044 | ATP-dependent chromatin remodeling | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 4 | 23 |
GO:0008135 | translation factor activity, nucleic acid binding | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 7 | 24 |
GO:0001707 | mesoderm formation | 2.06e-02 | 1.00e+00 | 5.587 | 1 | 1 | 25 |
GO:0042113 | B cell activation | 2.06e-02 | 1.00e+00 | 5.587 | 1 | 2 | 25 |
GO:0032735 | positive regulation of interleukin-12 production | 2.06e-02 | 1.00e+00 | 5.587 | 1 | 1 | 25 |
GO:0005515 | protein binding | 2.09e-02 | 1.00e+00 | 0.845 | 9 | 184 | 6024 |
GO:0010033 | response to organic substance | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 2 | 27 |
GO:0050661 | NADP binding | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 2 | 27 |
GO:0000188 | inactivation of MAPK activity | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 1 | 27 |
GO:0043022 | ribosome binding | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 3 | 27 |
GO:0031492 | nucleosomal DNA binding | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 4 | 27 |
GO:0001755 | neural crest cell migration | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 2 | 28 |
GO:0030669 | clathrin-coated endocytic vesicle membrane | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 4 | 28 |
GO:0019894 | kinesin binding | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 1 | 28 |
GO:0002027 | regulation of heart rate | 2.39e-02 | 1.00e+00 | 5.373 | 1 | 1 | 29 |
GO:0004712 | protein serine/threonine/tyrosine kinase activity | 2.39e-02 | 1.00e+00 | 5.373 | 1 | 4 | 29 |
GO:0042254 | ribosome biogenesis | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 1 | 30 |
GO:0033572 | transferrin transport | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 5 | 30 |
GO:0031623 | receptor internalization | 2.55e-02 | 1.00e+00 | 5.277 | 1 | 2 | 31 |
GO:0006833 | water transport | 2.55e-02 | 1.00e+00 | 5.277 | 1 | 1 | 31 |
GO:0071333 | cellular response to glucose stimulus | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 1 | 33 |
GO:0007411 | axon guidance | 2.78e-02 | 1.00e+00 | 2.914 | 2 | 13 | 319 |
GO:0032588 | trans-Golgi network membrane | 2.79e-02 | 1.00e+00 | 5.144 | 1 | 2 | 34 |
GO:0001895 | retina homeostasis | 2.79e-02 | 1.00e+00 | 5.144 | 1 | 1 | 34 |
GO:0071377 | cellular response to glucagon stimulus | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 2 | 35 |
GO:0034332 | adherens junction organization | 2.96e-02 | 1.00e+00 | 5.061 | 1 | 1 | 36 |
GO:0032755 | positive regulation of interleukin-6 production | 2.96e-02 | 1.00e+00 | 5.061 | 1 | 2 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 3.04e-02 | 1.00e+00 | 5.022 | 1 | 4 | 37 |
GO:0070527 | platelet aggregation | 3.12e-02 | 1.00e+00 | 4.983 | 1 | 2 | 38 |
GO:0032729 | positive regulation of interferon-gamma production | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 2 | 39 |
GO:0022627 | cytosolic small ribosomal subunit | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 4 | 39 |
GO:0007595 | lactation | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 2 | 39 |
GO:0031514 | motile cilium | 3.28e-02 | 1.00e+00 | 4.909 | 1 | 1 | 40 |
GO:0043195 | terminal bouton | 3.36e-02 | 1.00e+00 | 4.874 | 1 | 1 | 41 |
GO:0042110 | T cell activation | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 3 | 42 |
GO:0030136 | clathrin-coated vesicle | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 4 | 42 |
GO:0004722 | protein serine/threonine phosphatase activity | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 1 | 42 |
GO:0030155 | regulation of cell adhesion | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 2 | 42 |
GO:0006094 | gluconeogenesis | 3.52e-02 | 1.00e+00 | 4.805 | 1 | 5 | 43 |
GO:0006892 | post-Golgi vesicle-mediated transport | 3.52e-02 | 1.00e+00 | 4.805 | 1 | 3 | 43 |
GO:0021762 | substantia nigra development | 3.60e-02 | 1.00e+00 | 4.772 | 1 | 2 | 44 |
GO:0031594 | neuromuscular junction | 3.68e-02 | 1.00e+00 | 4.739 | 1 | 1 | 45 |
GO:0007266 | Rho protein signal transduction | 3.84e-02 | 1.00e+00 | 4.677 | 1 | 2 | 47 |
GO:0003743 | translation initiation factor activity | 4.00e-02 | 1.00e+00 | 4.616 | 1 | 8 | 49 |
GO:0035690 | cellular response to drug | 4.00e-02 | 1.00e+00 | 4.616 | 1 | 2 | 49 |
GO:0006521 | regulation of cellular amino acid metabolic process | 4.08e-02 | 1.00e+00 | 4.587 | 1 | 17 | 50 |
GO:0006986 | response to unfolded protein | 4.08e-02 | 1.00e+00 | 4.587 | 1 | 2 | 50 |
GO:0000775 | chromosome, centromeric region | 4.08e-02 | 1.00e+00 | 4.587 | 1 | 2 | 50 |
GO:0031100 | organ regeneration | 4.08e-02 | 1.00e+00 | 4.587 | 1 | 4 | 50 |
GO:0005905 | coated pit | 4.08e-02 | 1.00e+00 | 4.587 | 1 | 3 | 50 |
GO:0005615 | extracellular space | 4.08e-02 | 1.00e+00 | 1.914 | 3 | 17 | 957 |
GO:0040008 | regulation of growth | 4.08e-02 | 1.00e+00 | 4.587 | 1 | 5 | 50 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 4.32e-02 | 1.00e+00 | 4.503 | 1 | 5 | 53 |
GO:0045216 | cell-cell junction organization | 4.40e-02 | 1.00e+00 | 4.476 | 1 | 2 | 54 |
GO:0000932 | cytoplasmic mRNA processing body | 4.40e-02 | 1.00e+00 | 4.476 | 1 | 3 | 54 |
GO:0007202 | activation of phospholipase C activity | 4.48e-02 | 1.00e+00 | 4.450 | 1 | 3 | 55 |
GO:0002039 | p53 binding | 4.48e-02 | 1.00e+00 | 4.450 | 1 | 7 | 55 |
GO:0005739 | mitochondrion | 4.54e-02 | 1.00e+00 | 1.853 | 3 | 28 | 998 |
GO:0000502 | proteasome complex | 4.72e-02 | 1.00e+00 | 4.373 | 1 | 17 | 58 |
GO:0051087 | chaperone binding | 4.80e-02 | 1.00e+00 | 4.348 | 1 | 6 | 59 |
GO:0042995 | cell projection | 4.88e-02 | 1.00e+00 | 4.324 | 1 | 6 | 60 |
GO:0007059 | chromosome segregation | 5.04e-02 | 1.00e+00 | 4.277 | 1 | 4 | 62 |
GO:0030141 | secretory granule | 5.04e-02 | 1.00e+00 | 4.277 | 1 | 2 | 62 |
GO:0005634 | nucleus | 5.06e-02 | 1.00e+00 | 0.884 | 7 | 136 | 4559 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 5.20e-02 | 1.00e+00 | 4.231 | 1 | 19 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 5.28e-02 | 1.00e+00 | 4.209 | 1 | 22 | 65 |
GO:0006468 | protein phosphorylation | 5.42e-02 | 1.00e+00 | 2.386 | 2 | 18 | 460 |
GO:0003697 | single-stranded DNA binding | 5.52e-02 | 1.00e+00 | 4.144 | 1 | 5 | 68 |
GO:0034329 | cell junction assembly | 5.52e-02 | 1.00e+00 | 4.144 | 1 | 1 | 68 |
GO:0018105 | peptidyl-serine phosphorylation | 5.59e-02 | 1.00e+00 | 4.123 | 1 | 5 | 69 |
GO:0032587 | ruffle membrane | 5.67e-02 | 1.00e+00 | 4.102 | 1 | 3 | 70 |
GO:0055086 | nucleobase-containing small molecule metabolic process | 5.67e-02 | 1.00e+00 | 4.102 | 1 | 2 | 70 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 5.67e-02 | 1.00e+00 | 4.102 | 1 | 22 | 70 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 5.83e-02 | 1.00e+00 | 4.061 | 1 | 20 | 72 |
GO:0001843 | neural tube closure | 5.99e-02 | 1.00e+00 | 4.022 | 1 | 4 | 74 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 5.99e-02 | 1.00e+00 | 4.022 | 1 | 22 | 74 |
GO:0008584 | male gonad development | 6.07e-02 | 1.00e+00 | 4.002 | 1 | 3 | 75 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 6.07e-02 | 1.00e+00 | 4.002 | 1 | 20 | 75 |
GO:0001889 | liver development | 6.22e-02 | 1.00e+00 | 3.964 | 1 | 4 | 77 |
GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process | 6.22e-02 | 1.00e+00 | 3.964 | 1 | 7 | 77 |
GO:0007565 | female pregnancy | 6.30e-02 | 1.00e+00 | 3.946 | 1 | 1 | 78 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 6.38e-02 | 1.00e+00 | 3.927 | 1 | 23 | 79 |
GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | 6.46e-02 | 1.00e+00 | 3.909 | 1 | 3 | 80 |
GO:0050796 | regulation of insulin secretion | 6.54e-02 | 1.00e+00 | 3.891 | 1 | 4 | 81 |
GO:0019083 | viral transcription | 6.54e-02 | 1.00e+00 | 3.891 | 1 | 10 | 81 |
GO:0002576 | platelet degranulation | 6.62e-02 | 1.00e+00 | 3.874 | 1 | 4 | 82 |
GO:0006898 | receptor-mediated endocytosis | 6.77e-02 | 1.00e+00 | 3.839 | 1 | 3 | 84 |
GO:0006415 | translational termination | 7.01e-02 | 1.00e+00 | 3.788 | 1 | 10 | 87 |
GO:0050821 | protein stabilization | 7.08e-02 | 1.00e+00 | 3.772 | 1 | 2 | 88 |
GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II | 7.24e-02 | 1.00e+00 | 3.739 | 1 | 7 | 90 |
GO:0007010 | cytoskeleton organization | 7.32e-02 | 1.00e+00 | 3.723 | 1 | 1 | 91 |
GO:0042470 | melanosome | 7.32e-02 | 1.00e+00 | 3.723 | 1 | 9 | 91 |
GO:0006928 | cellular component movement | 7.32e-02 | 1.00e+00 | 3.723 | 1 | 7 | 91 |
GO:0005200 | structural constituent of cytoskeleton | 7.32e-02 | 1.00e+00 | 3.723 | 1 | 8 | 91 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 7.39e-02 | 1.00e+00 | 3.708 | 1 | 21 | 92 |
GO:0001649 | osteoblast differentiation | 7.39e-02 | 1.00e+00 | 3.708 | 1 | 6 | 92 |
GO:0006414 | translational elongation | 7.47e-02 | 1.00e+00 | 3.692 | 1 | 13 | 93 |
GO:0051082 | unfolded protein binding | 7.47e-02 | 1.00e+00 | 3.692 | 1 | 5 | 93 |
GO:0006915 | apoptotic process | 7.56e-02 | 1.00e+00 | 2.115 | 2 | 33 | 555 |
GO:0006112 | energy reserve metabolic process | 7.63e-02 | 1.00e+00 | 3.661 | 1 | 3 | 95 |
GO:0006470 | protein dephosphorylation | 7.86e-02 | 1.00e+00 | 3.616 | 1 | 1 | 98 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 8.32e-02 | 1.00e+00 | 3.531 | 1 | 10 | 104 |
GO:0014069 | postsynaptic density | 8.40e-02 | 1.00e+00 | 3.517 | 1 | 3 | 105 |
GO:0030308 | negative regulation of cell growth | 8.78e-02 | 1.00e+00 | 3.450 | 1 | 6 | 110 |
GO:0015630 | microtubule cytoskeleton | 8.78e-02 | 1.00e+00 | 3.450 | 1 | 4 | 110 |
GO:0006461 | protein complex assembly | 8.86e-02 | 1.00e+00 | 3.437 | 1 | 6 | 111 |
GO:0072562 | blood microparticle | 8.86e-02 | 1.00e+00 | 3.437 | 1 | 3 | 111 |
GO:0030529 | ribonucleoprotein complex | 8.93e-02 | 1.00e+00 | 3.424 | 1 | 8 | 112 |
GO:0005819 | spindle | 8.93e-02 | 1.00e+00 | 3.424 | 1 | 7 | 112 |
GO:0019058 | viral life cycle | 9.16e-02 | 1.00e+00 | 3.386 | 1 | 13 | 115 |
GO:0000209 | protein polyubiquitination | 9.24e-02 | 1.00e+00 | 3.373 | 1 | 20 | 116 |
GO:0006006 | glucose metabolic process | 9.39e-02 | 1.00e+00 | 3.348 | 1 | 7 | 118 |
GO:0006325 | chromatin organization | 9.39e-02 | 1.00e+00 | 3.348 | 1 | 5 | 118 |
GO:0030036 | actin cytoskeleton organization | 9.77e-02 | 1.00e+00 | 3.289 | 1 | 5 | 123 |
GO:0000790 | nuclear chromatin | 1.02e-01 | 1.00e+00 | 3.220 | 1 | 9 | 129 |
GO:0003735 | structural constituent of ribosome | 1.08e-01 | 1.00e+00 | 3.133 | 1 | 10 | 137 |
GO:0005911 | cell-cell junction | 1.08e-01 | 1.00e+00 | 3.144 | 1 | 4 | 136 |
GO:0007507 | heart development | 1.10e-01 | 1.00e+00 | 3.112 | 1 | 7 | 139 |
GO:0016887 | ATPase activity | 1.10e-01 | 1.00e+00 | 3.102 | 1 | 7 | 140 |
GO:0006457 | protein folding | 1.13e-01 | 1.00e+00 | 3.071 | 1 | 7 | 143 |
GO:0000082 | G1/S transition of mitotic cell cycle | 1.17e-01 | 1.00e+00 | 3.012 | 1 | 32 | 149 |
GO:0005198 | structural molecule activity | 1.18e-01 | 1.00e+00 | 3.002 | 1 | 5 | 150 |
GO:0042981 | regulation of apoptotic process | 1.18e-01 | 1.00e+00 | 3.002 | 1 | 24 | 150 |
GO:0005769 | early endosome | 1.19e-01 | 1.00e+00 | 2.983 | 1 | 2 | 152 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.29e-01 | 1.00e+00 | 2.865 | 1 | 7 | 165 |
GO:0030424 | axon | 1.30e-01 | 1.00e+00 | 2.856 | 1 | 4 | 166 |
GO:0006886 | intracellular protein transport | 1.33e-01 | 1.00e+00 | 2.813 | 1 | 5 | 171 |
GO:0034641 | cellular nitrogen compound metabolic process | 1.33e-01 | 1.00e+00 | 2.813 | 1 | 20 | 171 |
GO:0004672 | protein kinase activity | 1.38e-01 | 1.00e+00 | 2.764 | 1 | 6 | 177 |
GO:0031625 | ubiquitin protein ligase binding | 1.38e-01 | 1.00e+00 | 2.755 | 1 | 14 | 178 |
GO:0007173 | epidermal growth factor receptor signaling pathway | 1.46e-01 | 1.00e+00 | 2.669 | 1 | 12 | 189 |
GO:0005886 | plasma membrane | 1.53e-01 | 1.00e+00 | 0.897 | 4 | 45 | 2582 |
GO:0001701 | in utero embryonic development | 1.55e-01 | 1.00e+00 | 2.580 | 1 | 8 | 201 |
GO:0030168 | platelet activation | 1.58e-01 | 1.00e+00 | 2.552 | 1 | 10 | 205 |
GO:0007067 | mitotic nuclear division | 1.73e-01 | 1.00e+00 | 2.405 | 1 | 14 | 227 |
GO:0005759 | mitochondrial matrix | 1.74e-01 | 1.00e+00 | 2.398 | 1 | 14 | 228 |
GO:0008380 | RNA splicing | 1.74e-01 | 1.00e+00 | 2.398 | 1 | 11 | 228 |
GO:0043025 | neuronal cell body | 1.86e-01 | 1.00e+00 | 2.294 | 1 | 9 | 245 |
GO:0003779 | actin binding | 2.00e-01 | 1.00e+00 | 2.176 | 1 | 12 | 266 |
GO:0048011 | neurotrophin TRK receptor signaling pathway | 2.02e-01 | 1.00e+00 | 2.160 | 1 | 15 | 269 |
GO:0043065 | positive regulation of apoptotic process | 2.02e-01 | 1.00e+00 | 2.165 | 1 | 10 | 268 |
GO:0005743 | mitochondrial inner membrane | 2.08e-01 | 1.00e+00 | 2.117 | 1 | 8 | 277 |
GO:0019899 | enzyme binding | 2.08e-01 | 1.00e+00 | 2.117 | 1 | 12 | 277 |
GO:0005856 | cytoskeleton | 2.17e-01 | 1.00e+00 | 2.046 | 1 | 12 | 291 |
GO:0006200 | ATP catabolic process | 2.18e-01 | 1.00e+00 | 2.041 | 1 | 15 | 292 |
GO:0035556 | intracellular signal transduction | 2.25e-01 | 1.00e+00 | 1.988 | 1 | 9 | 303 |
GO:0005654 | nucleoplasm | 2.26e-01 | 1.00e+00 | 1.152 | 2 | 76 | 1082 |
GO:0005813 | centrosome | 2.40e-01 | 1.00e+00 | 1.882 | 1 | 14 | 326 |
GO:0003723 | RNA binding | 2.50e-01 | 1.00e+00 | 1.813 | 1 | 20 | 342 |
GO:0007155 | cell adhesion | 2.67e-01 | 1.00e+00 | 1.704 | 1 | 6 | 369 |
GO:0046982 | protein heterodimerization activity | 2.74e-01 | 1.00e+00 | 1.661 | 1 | 13 | 380 |
GO:0009986 | cell surface | 2.88e-01 | 1.00e+00 | 1.580 | 1 | 11 | 402 |
GO:0055114 | oxidation-reduction process | 2.99e-01 | 1.00e+00 | 1.517 | 1 | 12 | 420 |
GO:0055085 | transmembrane transport | 3.08e-01 | 1.00e+00 | 1.466 | 1 | 10 | 435 |
GO:0042802 | identical protein binding | 3.36e-01 | 1.00e+00 | 1.312 | 1 | 20 | 484 |
GO:0005737 | cytoplasm | 3.86e-01 | 1.00e+00 | 0.352 | 4 | 110 | 3767 |
GO:0007165 | signal transduction | 5.41e-01 | 1.00e+00 | 0.406 | 1 | 24 | 907 |
GO:0006355 | regulation of transcription, DNA-templated | 5.77e-01 | 1.00e+00 | 0.270 | 1 | 18 | 997 |
GO:0008270 | zinc ion binding | 5.77e-01 | 1.00e+00 | 0.270 | 1 | 12 | 997 |
GO:0046872 | metal ion binding | 6.80e-01 | 1.00e+00 | -0.121 | 1 | 25 | 1307 |
GO:0005730 | nucleolus | 7.65e-01 | 1.00e+00 | -0.449 | 1 | 69 | 1641 |