int-snw-5557

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	1.035	1.30e-19	2.30e-04	6.66e-03

wolf-screen-ratio-mammosphere-adherent-int-snw-5557 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
RPA2	6118	98	1.250	1.151	69	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
HSPD1	3329	35	0.913	1.035	286	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-
[ PRIM1 ]	5557	1	0.531	1.035	53	-	-

Interactions (6)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
HSPD1	3329	PRIM1	5557	pp	--	int.I2D: YeastLow
HSPD1	3329	RPSA	3921	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB	60	RPA2	6118	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
PRIM1	5557	RPA2	6118	pp	--	int.I2D: BioGrid
ACTB	60	HSPD1	3329	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastLow

Related GO terms (148)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0032201	telomere maintenance via semi-conservative replication	2.01e-05	2.90e-01	8.102	2	5	21
GO:0000722	telomere maintenance via recombination	2.88e-05	4.15e-01	7.850	2	5	25
GO:0006271	DNA strand elongation involved in DNA replication	4.17e-05	6.01e-01	7.587	2	7	30
GO:0000723	telomere maintenance	1.47e-04	1.00e+00	6.687	2	6	56
GO:0003697	single-stranded DNA binding	2.17e-04	1.00e+00	6.407	2	5	68
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	3.47e-04	1.00e+00	11.494	1	1	1
GO:0048291	isotype switching to IgG isotypes	3.47e-04	1.00e+00	11.494	1	1	1
GO:0002368	B cell cytokine production	3.47e-04	1.00e+00	11.494	1	1	1
GO:1990077	primosome complex	6.93e-04	1.00e+00	10.494	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	6.93e-04	1.00e+00	10.494	1	1	2
GO:0005055	laminin receptor activity	6.93e-04	1.00e+00	10.494	1	1	2
GO:0006407	rRNA export from nucleus	6.93e-04	1.00e+00	10.494	1	1	2
GO:0016020	membrane	8.34e-04	1.00e+00	2.779	4	90	1681
GO:0006458	'de novo' protein folding	1.04e-03	1.00e+00	9.909	1	1	3
GO:0030135	coated vesicle	1.04e-03	1.00e+00	9.909	1	1	3
GO:0000082	G1/S transition of mitotic cell cycle	1.04e-03	1.00e+00	5.275	2	32	149
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.39e-03	1.00e+00	9.494	1	1	4
GO:0030686	90S preribosome	1.39e-03	1.00e+00	9.494	1	1	4
GO:0003896	DNA primase activity	1.39e-03	1.00e+00	9.494	1	2	4
GO:0006269	DNA replication, synthesis of RNA primer	1.73e-03	1.00e+00	9.172	1	2	5
GO:0046696	lipopolysaccharide receptor complex	1.73e-03	1.00e+00	9.172	1	1	5
GO:0000730	DNA recombinase assembly	1.73e-03	1.00e+00	9.172	1	1	5
GO:2000001	regulation of DNA damage checkpoint	1.73e-03	1.00e+00	9.172	1	1	5
GO:0003688	DNA replication origin binding	2.08e-03	1.00e+00	8.909	1	2	6
GO:0030957	Tat protein binding	2.08e-03	1.00e+00	8.909	1	3	6
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	2.08e-03	1.00e+00	8.909	1	1	6
GO:0000028	ribosomal small subunit assembly	2.42e-03	1.00e+00	8.687	1	1	7
GO:0070688	MLL5-L complex	2.77e-03	1.00e+00	8.494	1	1	8
GO:0051604	protein maturation	2.77e-03	1.00e+00	8.494	1	1	8
GO:0010569	regulation of double-strand break repair via homologous recombination	3.46e-03	1.00e+00	8.172	1	1	10
GO:0043032	positive regulation of macrophage activation	3.46e-03	1.00e+00	8.172	1	1	10
GO:0005654	nucleoplasm	3.75e-03	1.00e+00	3.000	3	76	1082
GO:0032727	positive regulation of interferon-alpha production	3.81e-03	1.00e+00	8.035	1	1	11
GO:0031571	mitotic G1 DNA damage checkpoint	3.81e-03	1.00e+00	8.035	1	4	11
GO:0043234	protein complex	4.00e-03	1.00e+00	4.290	2	18	295
GO:0005662	DNA replication factor A complex	4.50e-03	1.00e+00	7.794	1	1	13
GO:0001530	lipopolysaccharide binding	4.50e-03	1.00e+00	7.794	1	3	13
GO:0051131	chaperone-mediated protein complex assembly	4.50e-03	1.00e+00	7.794	1	1	13
GO:0035267	NuA4 histone acetyltransferase complex	4.84e-03	1.00e+00	7.687	1	4	14
GO:0042026	protein refolding	5.19e-03	1.00e+00	7.587	1	2	15
GO:0050998	nitric-oxide synthase binding	5.54e-03	1.00e+00	7.494	1	1	16
GO:0050870	positive regulation of T cell activation	5.88e-03	1.00e+00	7.407	1	1	17
GO:0035861	site of double-strand break	6.23e-03	1.00e+00	7.324	1	1	18
GO:0032733	positive regulation of interleukin-10 production	6.57e-03	1.00e+00	7.246	1	1	19
GO:0006298	mismatch repair	6.92e-03	1.00e+00	7.172	1	3	20
GO:0000278	mitotic cell cycle	6.94e-03	1.00e+00	3.883	2	48	391
GO:0042100	B cell proliferation	7.26e-03	1.00e+00	7.102	1	1	21
GO:0000718	nucleotide-excision repair, DNA damage removal	7.26e-03	1.00e+00	7.102	1	4	21
GO:0006297	nucleotide-excision repair, DNA gap filling	7.60e-03	1.00e+00	7.035	1	3	22
GO:0030863	cortical cytoskeleton	7.60e-03	1.00e+00	7.035	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	7.60e-03	1.00e+00	7.035	1	4	22
GO:0006270	DNA replication initiation	7.60e-03	1.00e+00	7.035	1	6	22
GO:0043044	ATP-dependent chromatin remodeling	7.95e-03	1.00e+00	6.971	1	4	23
GO:0043236	laminin binding	7.95e-03	1.00e+00	6.971	1	1	23
GO:0042113	B cell activation	8.64e-03	1.00e+00	6.850	1	2	25
GO:0032735	positive regulation of interleukin-12 production	8.64e-03	1.00e+00	6.850	1	1	25
GO:0043022	ribosome binding	9.33e-03	1.00e+00	6.739	1	3	27
GO:0031492	nucleosomal DNA binding	9.33e-03	1.00e+00	6.739	1	4	27
GO:0019894	kinesin binding	9.67e-03	1.00e+00	6.687	1	1	28
GO:0044267	cellular protein metabolic process	1.01e-02	1.00e+00	3.605	2	29	474
GO:0001895	retina homeostasis	1.17e-02	1.00e+00	6.407	1	1	34
GO:0034332	adherens junction organization	1.24e-02	1.00e+00	6.324	1	1	36
GO:0032755	positive regulation of interleukin-6 production	1.24e-02	1.00e+00	6.324	1	2	36
GO:0016032	viral process	1.27e-02	1.00e+00	3.433	2	55	534
GO:0051084	'de novo' posttranslational protein folding	1.28e-02	1.00e+00	6.285	1	4	37
GO:0006284	base-excision repair	1.28e-02	1.00e+00	6.285	1	3	37
GO:0070527	platelet aggregation	1.31e-02	1.00e+00	6.246	1	2	38
GO:0032729	positive regulation of interferon-gamma production	1.34e-02	1.00e+00	6.209	1	2	39
GO:0022627	cytosolic small ribosomal subunit	1.34e-02	1.00e+00	6.209	1	4	39
GO:0000781	chromosome, telomeric region	1.34e-02	1.00e+00	6.209	1	3	39
GO:0042110	T cell activation	1.45e-02	1.00e+00	6.102	1	3	42
GO:0021762	substantia nigra development	1.52e-02	1.00e+00	6.035	1	2	44
GO:0006283	transcription-coupled nucleotide-excision repair	1.58e-02	1.00e+00	5.971	1	7	46
GO:0003684	damaged DNA binding	1.69e-02	1.00e+00	5.879	1	7	49
GO:0006986	response to unfolded protein	1.72e-02	1.00e+00	5.850	1	2	50
GO:0005905	coated pit	1.72e-02	1.00e+00	5.850	1	3	50
GO:0003725	double-stranded RNA binding	1.79e-02	1.00e+00	5.794	1	5	52
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	1.82e-02	1.00e+00	5.766	1	5	53
GO:0045216	cell-cell junction organization	1.86e-02	1.00e+00	5.739	1	2	54
GO:0000724	double-strand break repair via homologous recombination	1.89e-02	1.00e+00	5.713	1	3	55
GO:0002039	p53 binding	1.89e-02	1.00e+00	5.713	1	7	55
GO:0051087	chaperone binding	2.03e-02	1.00e+00	5.612	1	6	59
GO:0019903	protein phosphatase binding	2.13e-02	1.00e+00	5.540	1	4	62
GO:0006302	double-strand break repair	2.13e-02	1.00e+00	5.540	1	4	62
GO:0030141	secretory granule	2.13e-02	1.00e+00	5.540	1	2	62
GO:0006289	nucleotide-excision repair	2.34e-02	1.00e+00	5.407	1	11	68
GO:0034329	cell junction assembly	2.34e-02	1.00e+00	5.407	1	1	68
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	2.54e-02	1.00e+00	5.285	1	6	74
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	2.64e-02	1.00e+00	5.227	1	7	77
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	2.74e-02	1.00e+00	5.172	1	3	80
GO:0019083	viral transcription	2.78e-02	1.00e+00	5.154	1	10	81
GO:0047485	protein N-terminus binding	2.95e-02	1.00e+00	5.068	1	5	86
GO:0006415	translational termination	2.98e-02	1.00e+00	5.051	1	10	87
GO:0016605	PML body	3.01e-02	1.00e+00	5.035	1	3	88
GO:0050821	protein stabilization	3.01e-02	1.00e+00	5.035	1	2	88
GO:0006928	cellular component movement	3.12e-02	1.00e+00	4.986	1	7	91
GO:0005200	structural constituent of cytoskeleton	3.12e-02	1.00e+00	4.986	1	8	91
GO:0006414	translational elongation	3.18e-02	1.00e+00	4.955	1	13	93
GO:0051082	unfolded protein binding	3.18e-02	1.00e+00	4.955	1	5	93
GO:0070062	extracellular vesicular exosome	3.53e-02	1.00e+00	1.850	3	104	2400
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	3.55e-02	1.00e+00	4.794	1	10	104
GO:0014069	postsynaptic density	3.59e-02	1.00e+00	4.780	1	3	105
GO:0072562	blood microparticle	3.79e-02	1.00e+00	4.700	1	3	111
GO:0030529	ribonucleoprotein complex	3.82e-02	1.00e+00	4.687	1	8	112
GO:0005615	extracellular space	3.84e-02	1.00e+00	2.592	2	17	957
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	3.89e-02	1.00e+00	4.661	1	11	114
GO:0019058	viral life cycle	3.92e-02	1.00e+00	4.649	1	13	115
GO:0005829	cytosol	3.93e-02	1.00e+00	1.794	3	132	2496
GO:0006325	chromatin organization	4.02e-02	1.00e+00	4.612	1	5	118
GO:0006260	DNA replication	4.13e-02	1.00e+00	4.575	1	9	121
GO:0000790	nuclear chromatin	4.39e-02	1.00e+00	4.483	1	9	129
GO:0006413	translational initiation	4.46e-02	1.00e+00	4.461	1	17	131
GO:0044822	poly(A) RNA binding	4.62e-02	1.00e+00	2.450	2	49	1056
GO:0003735	structural constituent of ribosome	4.66e-02	1.00e+00	4.396	1	10	137
GO:0016887	ATPase activity	4.76e-02	1.00e+00	4.365	1	7	140
GO:0006457	protein folding	4.86e-02	1.00e+00	4.334	1	7	143
GO:0061024	membrane organization	4.93e-02	1.00e+00	4.314	1	7	145
GO:0005769	early endosome	5.16e-02	1.00e+00	4.246	1	2	152
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	5.59e-02	1.00e+00	4.128	1	7	165
GO:0030424	axon	5.62e-02	1.00e+00	4.119	1	4	166
GO:0031625	ubiquitin protein ligase binding	6.02e-02	1.00e+00	4.018	1	14	178
GO:0005524	ATP binding	6.73e-02	1.00e+00	2.152	2	60	1298
GO:0016071	mRNA metabolic process	7.50e-02	1.00e+00	3.693	1	31	223
GO:0005759	mitochondrial matrix	7.66e-02	1.00e+00	3.661	1	14	228
GO:0006412	translation	7.72e-02	1.00e+00	3.649	1	20	230
GO:0016070	RNA metabolic process	8.28e-02	1.00e+00	3.546	1	32	247
GO:0006281	DNA repair	8.73e-02	1.00e+00	3.466	1	18	261
GO:0043065	positive regulation of apoptotic process	8.95e-02	1.00e+00	3.428	1	10	268
GO:0005743	mitochondrial inner membrane	9.24e-02	1.00e+00	3.380	1	8	277
GO:0019899	enzyme binding	9.24e-02	1.00e+00	3.380	1	12	277
GO:0005856	cytoskeleton	9.69e-02	1.00e+00	3.309	1	12	291
GO:0006200	ATP catabolic process	9.72e-02	1.00e+00	3.304	1	15	292
GO:0005515	protein binding	1.01e-01	1.00e+00	0.938	4	184	6024
GO:0019901	protein kinase binding	1.05e-01	1.00e+00	3.186	1	21	317
GO:0007411	axon guidance	1.06e-01	1.00e+00	3.177	1	13	319
GO:0005737	cytoplasm	1.16e-01	1.00e+00	1.200	3	110	3767
GO:0005925	focal adhesion	1.21e-01	1.00e+00	2.978	1	19	366
GO:0007155	cell adhesion	1.22e-01	1.00e+00	2.967	1	6	369
GO:0009986	cell surface	1.32e-01	1.00e+00	2.843	1	11	402
GO:0043066	negative regulation of apoptotic process	1.39e-01	1.00e+00	2.766	1	31	424
GO:0007596	blood coagulation	1.48e-01	1.00e+00	2.664	1	18	455
GO:0045087	innate immune response	1.90e-01	1.00e+00	2.275	1	24	596
GO:0010467	gene expression	2.11e-01	1.00e+00	2.108	1	59	669
GO:0005886	plasma membrane	2.20e-01	1.00e+00	1.160	2	45	2582
GO:0005739	mitochondrion	3.01e-01	1.00e+00	1.531	1	28	998
GO:0046872	metal ion binding	3.78e-01	1.00e+00	1.142	1	25	1307
GO:0005730	nucleolus	4.53e-01	1.00e+00	0.814	1	69	1641
GO:0005634	nucleus	5.05e-01	1.00e+00	0.340	2	136	4559

Wolf-ratios-Mammosphere-Adherent

int-snw-5557

Statistics

Genes (5)

Interactions (6)

Related GO terms (148)