int-snw-4967

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	1.076	1.85e-21	7.57e-05	2.73e-03

wolf-screen-ratio-mammosphere-adherent-int-snw-4967 subnetwork

Genes (6)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
ACO2	50	50	1.000	1.076	191	Yes	-
PSMD11	5717	121	1.095	1.106	183	Yes	-
[ OGDH ]	4967	13	0.847	1.076	113	Yes	-
PSMD3	5709	57	0.986	1.106	146	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-
PGD	5226	75	1.201	1.106	138	Yes	-

Interactions (10)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMD3	5709	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
PGD	5226	PSMD3	5709	pp	--	int.I2D: YeastLow
OGDH	4967	PGD	5226	pp	--	int.I2D: YeastLow
OGDH	4967	PSMD11	5717	pp	--	int.I2D: YeastLow
OGDH	4967	PSMD3	5709	pp	--	int.I2D: YeastLow
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
ACO2	50	OGDH	4967	pp	--	int.I2D: YeastLow
ACO2	50	PSMD11	5717	pp	--	int.I2D: YeastLow
ACO2	50	PGD	5226	pp	--	int.I2D: YeastLow

Related GO terms (98)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005838	proteasome regulatory particle	9.50e-06	1.37e-01	8.646	2	7	12
GO:0022624	proteasome accessory complex	1.96e-05	2.82e-01	8.144	2	8	17
GO:0044281	small molecule metabolic process	2.31e-05	3.33e-01	3.311	5	58	1211
GO:0034641	cellular nitrogen compound metabolic process	3.19e-05	4.60e-01	5.398	3	20	171
GO:0006099	tricarboxylic acid cycle	5.43e-05	7.83e-01	7.424	2	4	28
GO:0016071	mRNA metabolic process	7.05e-05	1.00e+00	5.015	3	31	223
GO:0016070	RNA metabolic process	9.55e-05	1.00e+00	4.868	3	32	247
GO:0006091	generation of precursor metabolites and energy	1.75e-04	1.00e+00	6.587	2	3	50
GO:0006521	regulation of cellular amino acid metabolic process	1.75e-04	1.00e+00	6.587	2	17	50
GO:0000502	proteasome complex	2.36e-04	1.00e+00	6.373	2	17	58
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	2.87e-04	1.00e+00	6.231	2	19	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.97e-04	1.00e+00	6.209	2	22	65
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.44e-04	1.00e+00	6.102	2	22	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	3.64e-04	1.00e+00	6.061	2	20	72
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.84e-04	1.00e+00	6.022	2	22	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	3.95e-04	1.00e+00	6.002	2	20	75
GO:0019521	D-gluconate metabolic process	4.16e-04	1.00e+00	11.231	1	1	1
GO:0034602	oxoglutarate dehydrogenase (NAD+) activity	4.16e-04	1.00e+00	11.231	1	1	1
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	4.38e-04	1.00e+00	5.927	2	23	79
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	5.94e-04	1.00e+00	5.708	2	21	92
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	8.32e-04	1.00e+00	10.231	1	1	2
GO:0019322	pentose biosynthetic process	8.32e-04	1.00e+00	10.231	1	2	2
GO:0003994	aconitate hydratase activity	8.32e-04	1.00e+00	10.231	1	1	2
GO:0005055	laminin receptor activity	8.32e-04	1.00e+00	10.231	1	1	2
GO:0006407	rRNA export from nucleus	8.32e-04	1.00e+00	10.231	1	1	2
GO:0061034	olfactory bulb mitral cell layer development	8.32e-04	1.00e+00	10.231	1	1	2
GO:0045252	oxoglutarate dehydrogenase complex	8.32e-04	1.00e+00	10.231	1	2	2
GO:0051538	3 iron, 4 sulfur cluster binding	8.32e-04	1.00e+00	10.231	1	1	2
GO:0016032	viral process	9.28e-04	1.00e+00	3.755	3	55	534
GO:0000209	protein polyubiquitination	9.42e-04	1.00e+00	5.373	2	20	116
GO:0044237	cellular metabolic process	9.58e-04	1.00e+00	5.361	2	5	117
GO:0009051	pentose-phosphate shunt, oxidative branch	1.25e-03	1.00e+00	9.646	1	2	3
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	1.25e-03	1.00e+00	9.646	1	1	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	1.25e-03	1.00e+00	9.646	1	1	3
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	1.25e-03	1.00e+00	9.646	1	1	3
GO:0000082	G1/S transition of mitotic cell cycle	1.55e-03	1.00e+00	5.012	2	32	149
GO:0042981	regulation of apoptotic process	1.57e-03	1.00e+00	5.002	2	24	150
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.66e-03	1.00e+00	9.231	1	1	4
GO:0030686	90S preribosome	1.66e-03	1.00e+00	9.231	1	1	4
GO:0006734	NADH metabolic process	1.66e-03	1.00e+00	9.231	1	1	4
GO:0006104	succinyl-CoA metabolic process	1.66e-03	1.00e+00	9.231	1	1	4
GO:0010467	gene expression	1.79e-03	1.00e+00	3.430	3	59	669
GO:0043248	proteasome assembly	2.08e-03	1.00e+00	8.909	1	1	5
GO:0006102	isocitrate metabolic process	2.08e-03	1.00e+00	8.909	1	1	5
GO:0030976	thiamine pyrophosphate binding	2.08e-03	1.00e+00	8.909	1	1	5
GO:0006101	citrate metabolic process	2.49e-03	1.00e+00	8.646	1	1	6
GO:0021860	pyramidal neuron development	2.49e-03	1.00e+00	8.646	1	1	6
GO:0021695	cerebellar cortex development	2.49e-03	1.00e+00	8.646	1	2	6
GO:0000028	ribosomal small subunit assembly	2.91e-03	1.00e+00	8.424	1	1	7
GO:0006554	lysine catabolic process	3.32e-03	1.00e+00	8.231	1	2	8
GO:0005759	mitochondrial matrix	3.58e-03	1.00e+00	4.398	2	14	228
GO:0006098	pentose-phosphate shunt	4.15e-03	1.00e+00	7.909	1	4	10
GO:0021756	striatum development	4.15e-03	1.00e+00	7.909	1	1	10
GO:0021794	thalamus development	4.57e-03	1.00e+00	7.772	1	1	11
GO:0030234	enzyme regulator activity	5.40e-03	1.00e+00	7.531	1	3	13
GO:0006103	2-oxoglutarate metabolic process	6.64e-03	1.00e+00	7.231	1	1	16
GO:0042176	regulation of protein catabolic process	6.64e-03	1.00e+00	7.231	1	3	16
GO:0048863	stem cell differentiation	7.88e-03	1.00e+00	6.983	1	1	19
GO:0070062	extracellular vesicular exosome	8.64e-03	1.00e+00	2.002	4	104	2400
GO:0043236	laminin binding	9.53e-03	1.00e+00	6.708	1	1	23
GO:0005829	cytosol	9.98e-03	1.00e+00	1.946	4	132	2496
GO:0000278	mitotic cell cycle	1.02e-02	1.00e+00	3.620	2	48	391
GO:0043022	ribosome binding	1.12e-02	1.00e+00	6.476	1	3	27
GO:0050661	NADP binding	1.12e-02	1.00e+00	6.476	1	2	27
GO:0043066	negative regulation of apoptotic process	1.20e-02	1.00e+00	3.503	2	31	424
GO:0031072	heat shock protein binding	1.37e-02	1.00e+00	6.187	1	1	33
GO:0005634	nucleus	1.39e-02	1.00e+00	1.399	5	136	4559
GO:0051539	4 iron, 4 sulfur cluster binding	1.45e-02	1.00e+00	6.102	1	3	35
GO:0021766	hippocampus development	1.57e-02	1.00e+00	5.983	1	4	38
GO:0006096	glycolytic process	1.57e-02	1.00e+00	5.983	1	4	38
GO:0022627	cytosolic small ribosomal subunit	1.61e-02	1.00e+00	5.946	1	4	39
GO:0006915	apoptotic process	2.00e-02	1.00e+00	3.115	2	33	555
GO:0031966	mitochondrial membrane	2.27e-02	1.00e+00	5.450	1	1	55
GO:0016020	membrane	2.41e-02	1.00e+00	2.101	3	90	1681
GO:0051087	chaperone binding	2.43e-02	1.00e+00	5.348	1	6	59
GO:0019083	viral transcription	3.32e-02	1.00e+00	4.891	1	10	81
GO:0006415	translational termination	3.57e-02	1.00e+00	4.788	1	10	87
GO:0006414	translational elongation	3.81e-02	1.00e+00	4.692	1	13	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	4.25e-02	1.00e+00	4.531	1	10	104
GO:0005506	iron ion binding	4.29e-02	1.00e+00	4.517	1	4	105
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	4.65e-02	1.00e+00	4.398	1	11	114
GO:0019058	viral life cycle	4.69e-02	1.00e+00	4.386	1	13	115
GO:0006511	ubiquitin-dependent protein catabolic process	5.13e-02	1.00e+00	4.254	1	5	126
GO:0006413	translational initiation	5.33e-02	1.00e+00	4.198	1	17	131
GO:0003735	structural constituent of ribosome	5.57e-02	1.00e+00	4.133	1	10	137
GO:0005739	mitochondrion	5.95e-02	1.00e+00	2.268	2	28	998
GO:0005654	nucleoplasm	6.89e-02	1.00e+00	2.152	2	76	1082
GO:0006412	translation	9.20e-02	1.00e+00	3.386	1	20	230
GO:0005975	carbohydrate metabolic process	1.01e-01	1.00e+00	3.248	1	9	253
GO:0007155	cell adhesion	1.44e-01	1.00e+00	2.704	1	6	369
GO:0055114	oxidation-reduction process	1.63e-01	1.00e+00	2.517	1	12	420
GO:0044267	cellular protein metabolic process	1.82e-01	1.00e+00	2.342	1	29	474
GO:0044822	poly(A) RNA binding	3.66e-01	1.00e+00	1.187	1	49	1056
GO:0046872	metal ion binding	4.35e-01	1.00e+00	0.879	1	25	1307
GO:0005737	cytoplasm	4.92e-01	1.00e+00	0.352	2	110	3767
GO:0005730	nucleolus	5.16e-01	1.00e+00	0.551	1	69	1641
GO:0005886	plasma membrane	6.94e-01	1.00e+00	-0.103	1	45	2582
GO:0005515	protein binding	7.93e-01	1.00e+00	-0.325	2	184	6024

Wolf-ratios-Mammosphere-Adherent

int-snw-4967

Statistics

Genes (6)

Interactions (10)

Related GO terms (98)