int-snw-4801

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.938	1.22e-15	2.30e-03	3.81e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-4801 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
RPS11	6205	36	0.993	1.113	175	Yes	-
RPL14	9045	42	1.250	1.113	143	Yes	-
PSMD11	5717	121	1.095	1.106	183	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
HSPD1	3329	35	0.913	1.035	286	Yes	-
[ NFYB ]	4801	1	-0.056	0.938	69	-	-
RPSA	3921	156	1.327	1.151	152	Yes	-
RPL11	6135	9	0.718	1.017	200	Yes	-

Interactions (12)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
NFYB	4801	RPL11	6135	pp	--	int.I2D: BioGrid_Yeast
RPSA	3921	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
RPL11	6135	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
RPSA	3921	NFYB	4801	pp	--	int.I2D: BioGrid_Yeast
HSPD1	3329	RPSA	3921	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
RPL11	6135	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
RPS11	6205	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RPL11	6135	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
ACTB	60	HSPD1	3329	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastLow

Related GO terms (157)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0016071	mRNA metabolic process	4.56e-08	6.57e-04	5.337	5	31	223
GO:0019083	viral transcription	6.35e-08	9.16e-04	6.476	4	10	81
GO:0016032	viral process	6.59e-08	9.50e-04	4.340	6	55	534
GO:0016070	RNA metabolic process	7.60e-08	1.10e-03	5.190	5	32	247
GO:0006415	translational termination	8.49e-08	1.22e-03	6.373	4	10	87
GO:0006414	translational elongation	1.11e-07	1.60e-03	6.277	4	13	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.75e-07	2.52e-03	6.116	4	10	104
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	2.53e-07	3.65e-03	5.983	4	11	114
GO:0019058	viral life cycle	2.62e-07	3.78e-03	5.971	4	13	115
GO:0006413	translational initiation	4.42e-07	6.38e-03	5.783	4	17	131
GO:0003735	structural constituent of ribosome	5.30e-07	7.64e-03	5.718	4	10	137
GO:0044267	cellular protein metabolic process	1.94e-06	2.79e-02	4.249	5	29	474
GO:0016020	membrane	2.08e-06	3.00e-02	2.908	7	90	1681
GO:0006412	translation	4.19e-06	6.05e-02	4.971	4	20	230
GO:0010467	gene expression	1.05e-05	1.52e-01	3.752	5	59	669
GO:0042273	ribosomal large subunit biogenesis	2.09e-05	3.02e-01	8.116	2	4	13
GO:0070062	extracellular vesicular exosome	2.40e-05	3.46e-01	2.395	7	104	2400
GO:0005829	cytosol	3.14e-05	4.52e-01	2.338	7	132	2496
GO:0019843	rRNA binding	9.38e-05	1.00e+00	7.061	2	3	27
GO:0044822	poly(A) RNA binding	9.68e-05	1.00e+00	3.094	5	49	1056
GO:0022627	cytosolic small ribosomal subunit	1.97e-04	1.00e+00	6.531	2	4	39
GO:0022625	cytosolic large ribosomal subunit	3.12e-04	1.00e+00	6.201	2	6	49
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	5.55e-04	1.00e+00	10.816	1	1	1
GO:0048291	isotype switching to IgG isotypes	5.55e-04	1.00e+00	10.816	1	1	1
GO:0002368	B cell cytokine production	5.55e-04	1.00e+00	10.816	1	1	1
GO:0005515	protein binding	9.24e-04	1.00e+00	1.260	8	184	6024
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.11e-03	1.00e+00	9.816	1	1	2
GO:0005055	laminin receptor activity	1.11e-03	1.00e+00	9.816	1	1	2
GO:0006407	rRNA export from nucleus	1.11e-03	1.00e+00	9.816	1	1	2
GO:0006364	rRNA processing	1.15e-03	1.00e+00	5.261	2	6	94
GO:0006458	'de novo' protein folding	1.66e-03	1.00e+00	9.231	1	1	3
GO:0030135	coated vesicle	1.66e-03	1.00e+00	9.231	1	1	3
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.22e-03	1.00e+00	8.816	1	1	4
GO:0030686	90S preribosome	2.22e-03	1.00e+00	8.816	1	1	4
GO:0016602	CCAAT-binding factor complex	2.22e-03	1.00e+00	8.816	1	1	4
GO:0043248	proteasome assembly	2.77e-03	1.00e+00	8.494	1	1	5
GO:0046696	lipopolysaccharide receptor complex	2.77e-03	1.00e+00	8.494	1	1	5
GO:0003688	DNA replication origin binding	3.32e-03	1.00e+00	8.231	1	2	6
GO:0030957	Tat protein binding	3.32e-03	1.00e+00	8.231	1	3	6
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	3.32e-03	1.00e+00	8.231	1	1	6
GO:0000028	ribosomal small subunit assembly	3.88e-03	1.00e+00	8.009	1	1	7
GO:0070688	MLL5-L complex	4.43e-03	1.00e+00	7.816	1	1	8
GO:0051604	protein maturation	4.43e-03	1.00e+00	7.816	1	1	8
GO:0043032	positive regulation of macrophage activation	5.53e-03	1.00e+00	7.494	1	1	10
GO:0032727	positive regulation of interferon-alpha production	6.09e-03	1.00e+00	7.357	1	1	11
GO:0005838	proteasome regulatory particle	6.64e-03	1.00e+00	7.231	1	7	12
GO:0001530	lipopolysaccharide binding	7.19e-03	1.00e+00	7.116	1	3	13
GO:0051131	chaperone-mediated protein complex assembly	7.19e-03	1.00e+00	7.116	1	1	13
GO:0035267	NuA4 histone acetyltransferase complex	7.74e-03	1.00e+00	7.009	1	4	14
GO:0042026	protein refolding	8.29e-03	1.00e+00	6.909	1	2	15
GO:0050998	nitric-oxide synthase binding	8.84e-03	1.00e+00	6.816	1	1	16
GO:0050870	positive regulation of T cell activation	9.39e-03	1.00e+00	6.729	1	1	17
GO:0022624	proteasome accessory complex	9.39e-03	1.00e+00	6.729	1	8	17
GO:0032733	positive regulation of interleukin-10 production	1.05e-02	1.00e+00	6.568	1	1	19
GO:0048863	stem cell differentiation	1.05e-02	1.00e+00	6.568	1	1	19
GO:0043234	protein complex	1.08e-02	1.00e+00	3.612	2	18	295
GO:0042100	B cell proliferation	1.16e-02	1.00e+00	6.424	1	1	21
GO:0030863	cortical cytoskeleton	1.21e-02	1.00e+00	6.357	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	1.21e-02	1.00e+00	6.357	1	4	22
GO:0043044	ATP-dependent chromatin remodeling	1.27e-02	1.00e+00	6.293	1	4	23
GO:0043236	laminin binding	1.27e-02	1.00e+00	6.293	1	1	23
GO:0042113	B cell activation	1.38e-02	1.00e+00	6.172	1	2	25
GO:0032735	positive regulation of interleukin-12 production	1.38e-02	1.00e+00	6.172	1	1	25
GO:0003723	RNA binding	1.43e-02	1.00e+00	3.398	2	20	342
GO:0043022	ribosome binding	1.49e-02	1.00e+00	6.061	1	3	27
GO:0031492	nucleosomal DNA binding	1.49e-02	1.00e+00	6.061	1	4	27
GO:0070491	repressing transcription factor binding	1.54e-02	1.00e+00	6.009	1	1	28
GO:0019894	kinesin binding	1.54e-02	1.00e+00	6.009	1	1	28
GO:0034504	protein localization to nucleus	1.54e-02	1.00e+00	6.009	1	2	28
GO:0005925	focal adhesion	1.63e-02	1.00e+00	3.300	2	19	366
GO:0005654	nucleoplasm	1.77e-02	1.00e+00	2.322	3	76	1082
GO:0001895	retina homeostasis	1.87e-02	1.00e+00	5.729	1	1	34
GO:0006605	protein targeting	1.93e-02	1.00e+00	5.687	1	2	35
GO:0034332	adherens junction organization	1.98e-02	1.00e+00	5.646	1	1	36
GO:0032755	positive regulation of interleukin-6 production	1.98e-02	1.00e+00	5.646	1	2	36
GO:0051084	'de novo' posttranslational protein folding	2.03e-02	1.00e+00	5.607	1	4	37
GO:0070527	platelet aggregation	2.09e-02	1.00e+00	5.568	1	2	38
GO:0032729	positive regulation of interferon-gamma production	2.14e-02	1.00e+00	5.531	1	2	39
GO:0043066	negative regulation of apoptotic process	2.15e-02	1.00e+00	3.088	2	31	424
GO:0042110	T cell activation	2.31e-02	1.00e+00	5.424	1	3	42
GO:0021762	substantia nigra development	2.42e-02	1.00e+00	5.357	1	2	44
GO:0006521	regulation of cellular amino acid metabolic process	2.74e-02	1.00e+00	5.172	1	17	50
GO:0006986	response to unfolded protein	2.74e-02	1.00e+00	5.172	1	2	50
GO:0005905	coated pit	2.74e-02	1.00e+00	5.172	1	3	50
GO:0003725	double-stranded RNA binding	2.85e-02	1.00e+00	5.116	1	5	52
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.90e-02	1.00e+00	5.088	1	5	53
GO:0045216	cell-cell junction organization	2.96e-02	1.00e+00	5.061	1	2	54
GO:0002039	p53 binding	3.01e-02	1.00e+00	5.035	1	7	55
GO:0005840	ribosome	3.17e-02	1.00e+00	4.958	1	1	58
GO:0000502	proteasome complex	3.17e-02	1.00e+00	4.958	1	17	58
GO:0051087	chaperone binding	3.23e-02	1.00e+00	4.933	1	6	59
GO:0030141	secretory granule	3.39e-02	1.00e+00	4.862	1	2	62
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	3.50e-02	1.00e+00	4.816	1	19	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.55e-02	1.00e+00	4.794	1	22	65
GO:0034329	cell junction assembly	3.71e-02	1.00e+00	4.729	1	1	68
GO:0003697	single-stranded DNA binding	3.71e-02	1.00e+00	4.729	1	5	68
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.82e-02	1.00e+00	4.687	1	22	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	3.93e-02	1.00e+00	4.646	1	20	72
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	4.03e-02	1.00e+00	4.607	1	6	74
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.03e-02	1.00e+00	4.607	1	22	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	4.09e-02	1.00e+00	4.587	1	20	75
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	4.19e-02	1.00e+00	4.549	1	7	77
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	4.30e-02	1.00e+00	4.512	1	23	79
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	4.35e-02	1.00e+00	4.494	1	3	80
GO:0050821	protein stabilization	4.78e-02	1.00e+00	4.357	1	2	88
GO:0006928	cellular component movement	4.94e-02	1.00e+00	4.308	1	7	91
GO:0005200	structural constituent of cytoskeleton	4.94e-02	1.00e+00	4.308	1	8	91
GO:0001649	osteoblast differentiation	4.99e-02	1.00e+00	4.293	1	6	92
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	4.99e-02	1.00e+00	4.293	1	21	92
GO:0051082	unfolded protein binding	5.04e-02	1.00e+00	4.277	1	5	93
GO:0014069	postsynaptic density	5.68e-02	1.00e+00	4.102	1	3	105
GO:0072562	blood microparticle	5.99e-02	1.00e+00	4.022	1	3	111
GO:0030529	ribonucleoprotein complex	6.05e-02	1.00e+00	4.009	1	8	112
GO:0000209	protein polyubiquitination	6.26e-02	1.00e+00	3.958	1	20	116
GO:0006325	chromatin organization	6.36e-02	1.00e+00	3.933	1	5	118
GO:0006511	ubiquitin-dependent protein catabolic process	6.78e-02	1.00e+00	3.839	1	5	126
GO:0000790	nuclear chromatin	6.94e-02	1.00e+00	3.805	1	9	129
GO:0044255	cellular lipid metabolic process	7.15e-02	1.00e+00	3.761	1	6	133
GO:0016887	ATPase activity	7.51e-02	1.00e+00	3.687	1	7	140
GO:0006457	protein folding	7.66e-02	1.00e+00	3.656	1	7	143
GO:0061024	membrane organization	7.77e-02	1.00e+00	3.636	1	7	145
GO:0000082	G1/S transition of mitotic cell cycle	7.97e-02	1.00e+00	3.597	1	32	149
GO:0042981	regulation of apoptotic process	8.03e-02	1.00e+00	3.587	1	24	150
GO:0005769	early endosome	8.13e-02	1.00e+00	3.568	1	2	152
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	8.80e-02	1.00e+00	3.450	1	7	165
GO:0030424	axon	8.85e-02	1.00e+00	3.441	1	4	166
GO:0044212	transcription regulatory region DNA binding	8.95e-02	1.00e+00	3.424	1	6	168
GO:0034641	cellular nitrogen compound metabolic process	9.10e-02	1.00e+00	3.398	1	20	171
GO:0005615	extracellular space	9.43e-02	1.00e+00	1.914	2	17	957
GO:0032403	protein complex binding	9.71e-02	1.00e+00	3.300	1	10	183
GO:0005759	mitochondrial matrix	1.20e-01	1.00e+00	2.983	1	14	228
GO:0005737	cytoplasm	1.30e-01	1.00e+00	0.937	4	110	3767
GO:0043065	positive regulation of apoptotic process	1.39e-01	1.00e+00	2.750	1	10	268
GO:0044281	small molecule metabolic process	1.41e-01	1.00e+00	1.574	2	58	1211
GO:0005743	mitochondrial inner membrane	1.44e-01	1.00e+00	2.702	1	8	277
GO:0005856	cytoskeleton	1.50e-01	1.00e+00	2.631	1	12	291
GO:0006200	ATP catabolic process	1.51e-01	1.00e+00	2.626	1	15	292
GO:0005524	ATP binding	1.58e-01	1.00e+00	1.474	2	60	1298
GO:0019901	protein kinase binding	1.63e-01	1.00e+00	2.508	1	21	317
GO:0007411	axon guidance	1.64e-01	1.00e+00	2.499	1	13	319
GO:0043565	sequence-specific DNA binding	1.77e-01	1.00e+00	2.381	1	6	346
GO:0007155	cell adhesion	1.87e-01	1.00e+00	2.289	1	6	369
GO:0046982	protein heterodimerization activity	1.92e-01	1.00e+00	2.246	1	13	380
GO:0000278	mitotic cell cycle	1.97e-01	1.00e+00	2.205	1	48	391
GO:0009986	cell surface	2.02e-01	1.00e+00	2.165	1	11	402
GO:0007596	blood coagulation	2.26e-01	1.00e+00	1.986	1	18	455
GO:0045893	positive regulation of transcription, DNA-templated	2.36e-01	1.00e+00	1.915	1	13	478
GO:0006915	apoptotic process	2.69e-01	1.00e+00	1.700	1	33	555
GO:0045087	innate immune response	2.87e-01	1.00e+00	1.597	1	24	596
GO:0003700	sequence-specific DNA binding transcription factor activity	3.28e-01	1.00e+00	1.367	1	11	699
GO:0005886	plasma membrane	4.34e-01	1.00e+00	0.482	2	45	2582
GO:0006355	regulation of transcription, DNA-templated	4.36e-01	1.00e+00	0.855	1	18	997
GO:0005739	mitochondrion	4.37e-01	1.00e+00	0.853	1	28	998
GO:0005634	nucleus	4.89e-01	1.00e+00	0.247	3	136	4559
GO:0003677	DNA binding	5.06e-01	1.00e+00	0.566	1	28	1218
GO:0006351	transcription, DNA-templated	5.71e-01	1.00e+00	0.318	1	31	1446
GO:0005730	nucleolus	6.20e-01	1.00e+00	0.136	1	69	1641

Wolf-ratios-Mammosphere-Adherent

int-snw-4801

Statistics

Genes (8)

Interactions (12)

Related GO terms (157)