int-snw-1983

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.976	3.80e-17	9.77e-04	2.02e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-1983 subnetwork

Genes (10)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PES1	23481	2	0.513	0.976	163	Yes	-
RSL24D1	51187	36	1.300	1.020	59	Yes	-
EIF2S2	8894	27	1.075	1.138	81	Yes	-
RPS11	6205	36	0.993	1.113	175	Yes	-
RPL14	9045	42	1.250	1.113	143	Yes	-
RPL6	6128	11	0.844	1.113	164	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
[ EIF5 ]	1983	1	0.107	0.976	69	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-
PGD	5226	75	1.201	1.106	138	Yes	-

Interactions (13)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
RPL6	6128	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
RPSA	3921	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
EIF5	1983	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
EIF5	1983	RPL6	6128	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
EIF5	1983	EIF2S2	8894	pp	--	int.I2D: BioGrid_Yeast, HPRD, BCI, BioGrid; int.HPRD: in vitro, in vivo
PGD	5226	PES1	23481	pp	--	int.I2D: YeastLow
RPL6	6128	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
EIF2S2	8894	PES1	23481	pp	--	int.I2D: YeastLow
PES1	23481	RSL24D1	51187	pp	--	int.I2D: BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MIPS, YeastLow
EIF5	1983	PES1	23481	pp	--	int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast
ACTB	60	RPL6	6128	pp	--	int.I2D: BioGrid_Yeast
RPS11	6205	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast

Related GO terms (112)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006413	translational initiation	1.02e-10	1.47e-06	6.046	6	17	131
GO:0006412	translation	3.07e-09	4.43e-05	5.234	6	20	230
GO:0044267	cellular protein metabolic process	4.37e-09	6.30e-05	4.413	7	29	474
GO:0019083	viral transcription	1.89e-07	2.73e-03	6.154	4	10	81
GO:0006415	translational termination	2.52e-07	3.64e-03	6.051	4	10	87
GO:0006414	translational elongation	3.30e-07	4.76e-03	5.955	4	13	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	5.18e-07	7.47e-03	5.794	4	10	104
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	7.49e-07	1.08e-02	5.661	4	11	114
GO:0019058	viral life cycle	7.76e-07	1.12e-02	5.649	4	13	115
GO:0044822	poly(A) RNA binding	1.09e-06	1.57e-02	3.257	7	49	1056
GO:0003735	structural constituent of ribosome	1.57e-06	2.26e-02	5.396	4	10	137
GO:0010467	gene expression	1.74e-06	2.51e-02	3.693	6	59	669
GO:0016071	mRNA metabolic process	1.09e-05	1.57e-01	4.693	4	31	223
GO:0016070	RNA metabolic process	1.63e-05	2.34e-01	4.546	4	32	247
GO:0005829	cytosol	2.57e-05	3.71e-01	2.209	8	132	2496
GO:0042273	ribosomal large subunit biogenesis	3.36e-05	4.85e-01	7.794	2	4	13
GO:0036464	cytoplasmic ribonucleoprotein granule	9.92e-05	1.00e+00	7.035	2	4	22
GO:0008135	translation factor activity, nucleic acid binding	1.18e-04	1.00e+00	6.909	2	7	24
GO:0022627	cytosolic small ribosomal subunit	3.16e-04	1.00e+00	6.209	2	4	39
GO:0016032	viral process	3.27e-04	1.00e+00	3.433	4	55	534
GO:0016020	membrane	3.44e-04	1.00e+00	2.364	6	90	1681
GO:0003743	translation initiation factor activity	5.00e-04	1.00e+00	5.879	2	8	49
GO:0022625	cytosolic large ribosomal subunit	5.00e-04	1.00e+00	5.879	2	6	49
GO:0019521	D-gluconate metabolic process	6.93e-04	1.00e+00	10.494	1	1	1
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.39e-03	1.00e+00	9.494	1	1	2
GO:0002176	male germ cell proliferation	1.39e-03	1.00e+00	9.494	1	1	2
GO:0019322	pentose biosynthetic process	1.39e-03	1.00e+00	9.494	1	2	2
GO:0005055	laminin receptor activity	1.39e-03	1.00e+00	9.494	1	1	2
GO:0006407	rRNA export from nucleus	1.39e-03	1.00e+00	9.494	1	1	2
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.39e-03	1.00e+00	9.494	1	1	2
GO:0003723	RNA binding	1.40e-03	1.00e+00	3.661	3	20	342
GO:0005925	focal adhesion	1.70e-03	1.00e+00	3.563	3	19	366
GO:0006364	rRNA processing	1.83e-03	1.00e+00	4.940	2	6	94
GO:0005850	eukaryotic translation initiation factor 2 complex	2.08e-03	1.00e+00	8.909	1	1	3
GO:0009051	pentose-phosphate shunt, oxidative branch	2.08e-03	1.00e+00	8.909	1	2	3
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.08e-03	1.00e+00	8.909	1	1	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	2.08e-03	1.00e+00	8.909	1	1	3
GO:0030687	preribosome, large subunit precursor	2.08e-03	1.00e+00	8.909	1	1	3
GO:0070545	PeBoW complex	2.08e-03	1.00e+00	8.909	1	1	3
GO:0007000	nucleolus organization	2.77e-03	1.00e+00	8.494	1	1	4
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.77e-03	1.00e+00	8.494	1	1	4
GO:0030686	90S preribosome	2.77e-03	1.00e+00	8.494	1	1	4
GO:0030957	Tat protein binding	4.15e-03	1.00e+00	7.909	1	3	6
GO:0000028	ribosomal small subunit assembly	4.84e-03	1.00e+00	7.687	1	1	7
GO:0070688	MLL5-L complex	5.53e-03	1.00e+00	7.494	1	1	8
GO:0006098	pentose-phosphate shunt	6.91e-03	1.00e+00	7.172	1	4	10
GO:0035267	NuA4 histone acetyltransferase complex	9.67e-03	1.00e+00	6.687	1	4	14
GO:0050998	nitric-oxide synthase binding	1.10e-02	1.00e+00	6.494	1	1	16
GO:0033365	protein localization to organelle	1.10e-02	1.00e+00	6.494	1	1	16
GO:0000793	condensed chromosome	1.45e-02	1.00e+00	6.102	1	1	21
GO:0043021	ribonucleoprotein complex binding	1.45e-02	1.00e+00	6.102	1	1	21
GO:0030863	cortical cytoskeleton	1.52e-02	1.00e+00	6.035	1	1	22
GO:0070062	extracellular vesicular exosome	1.53e-02	1.00e+00	1.587	5	104	2400
GO:0043044	ATP-dependent chromatin remodeling	1.58e-02	1.00e+00	5.971	1	4	23
GO:0043236	laminin binding	1.58e-02	1.00e+00	5.971	1	1	23
GO:0031492	nucleosomal DNA binding	1.86e-02	1.00e+00	5.739	1	4	27
GO:0019843	rRNA binding	1.86e-02	1.00e+00	5.739	1	3	27
GO:0043022	ribosome binding	1.86e-02	1.00e+00	5.739	1	3	27
GO:0050661	NADP binding	1.86e-02	1.00e+00	5.739	1	2	27
GO:0019894	kinesin binding	1.93e-02	1.00e+00	5.687	1	1	28
GO:0042254	ribosome biogenesis	2.06e-02	1.00e+00	5.587	1	1	30
GO:0001895	retina homeostasis	2.33e-02	1.00e+00	5.407	1	1	34
GO:0034332	adherens junction organization	2.47e-02	1.00e+00	5.324	1	1	36
GO:0006446	regulation of translational initiation	2.47e-02	1.00e+00	5.324	1	4	36
GO:0051084	'de novo' posttranslational protein folding	2.54e-02	1.00e+00	5.285	1	4	37
GO:0070527	platelet aggregation	2.60e-02	1.00e+00	5.246	1	2	38
GO:0021762	substantia nigra development	3.01e-02	1.00e+00	5.035	1	2	44
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	3.62e-02	1.00e+00	4.766	1	5	53
GO:0045216	cell-cell junction organization	3.68e-02	1.00e+00	4.739	1	2	54
GO:0005840	ribosome	3.95e-02	1.00e+00	4.636	1	1	58
GO:0034329	cell junction assembly	4.62e-02	1.00e+00	4.407	1	1	68
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	5.02e-02	1.00e+00	4.285	1	6	74
GO:0008584	male gonad development	5.08e-02	1.00e+00	4.265	1	3	75
GO:0005200	structural constituent of cytoskeleton	6.14e-02	1.00e+00	3.986	1	8	91
GO:0006928	cellular component movement	6.14e-02	1.00e+00	3.986	1	7	91
GO:0001649	osteoblast differentiation	6.20e-02	1.00e+00	3.971	1	6	92
GO:0051726	regulation of cell cycle	6.53e-02	1.00e+00	3.894	1	5	97
GO:0014069	postsynaptic density	7.05e-02	1.00e+00	3.780	1	3	105
GO:0072562	blood microparticle	7.44e-02	1.00e+00	3.700	1	3	111
GO:0030529	ribonucleoprotein complex	7.50e-02	1.00e+00	3.687	1	8	112
GO:0006325	chromatin organization	7.89e-02	1.00e+00	3.612	1	5	118
GO:0000790	nuclear chromatin	8.60e-02	1.00e+00	3.483	1	9	129
GO:0005737	cytoplasm	9.18e-02	1.00e+00	0.937	5	110	3767
GO:0006457	protein folding	9.49e-02	1.00e+00	3.334	1	7	143
GO:0061024	membrane organization	9.61e-02	1.00e+00	3.314	1	7	145
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.09e-01	1.00e+00	3.128	1	7	165
GO:0030424	axon	1.09e-01	1.00e+00	3.119	1	4	166
GO:0003924	GTPase activity	1.29e-01	1.00e+00	2.872	1	12	197
GO:0001701	in utero embryonic development	1.31e-01	1.00e+00	2.843	1	8	201
GO:0006184	GTP catabolic process	1.39e-01	1.00e+00	2.753	1	12	214
GO:0005975	carbohydrate metabolic process	1.62e-01	1.00e+00	2.511	1	9	253
GO:0005654	nucleoplasm	1.70e-01	1.00e+00	1.415	2	76	1082
GO:0005856	cytoskeleton	1.84e-01	1.00e+00	2.309	1	12	291
GO:0043234	protein complex	1.87e-01	1.00e+00	2.290	1	18	295
GO:0005525	GTP binding	1.95e-01	1.00e+00	2.218	1	12	310
GO:0005515	protein binding	1.97e-01	1.00e+00	0.523	6	184	6024
GO:0019901	protein kinase binding	1.99e-01	1.00e+00	2.186	1	21	317
GO:0007411	axon guidance	2.00e-01	1.00e+00	2.177	1	13	319
GO:0008283	cell proliferation	2.06e-01	1.00e+00	2.137	1	14	328
GO:0007155	cell adhesion	2.28e-01	1.00e+00	1.967	1	6	369
GO:0055114	oxidation-reduction process	2.56e-01	1.00e+00	1.780	1	12	420
GO:0007596	blood coagulation	2.74e-01	1.00e+00	1.664	1	18	455
GO:0005730	nucleolus	3.18e-01	1.00e+00	0.814	2	69	1641
GO:0045087	innate immune response	3.44e-01	1.00e+00	1.275	1	24	596
GO:0005615	extracellular space	4.97e-01	1.00e+00	0.592	1	17	957
GO:0006355	regulation of transcription, DNA-templated	5.12e-01	1.00e+00	0.533	1	18	997
GO:0005886	plasma membrane	5.58e-01	1.00e+00	0.160	2	45	2582
GO:0044281	small molecule metabolic process	5.84e-01	1.00e+00	0.252	1	58	1211
GO:0003677	DNA binding	5.86e-01	1.00e+00	0.244	1	28	1218
GO:0005524	ATP binding	6.11e-01	1.00e+00	0.152	1	60	1298
GO:0046872	metal ion binding	6.13e-01	1.00e+00	0.142	1	25	1307
GO:0005634	nucleus	6.59e-01	1.00e+00	-0.075	3	136	4559

Wolf-ratios-Mammosphere-Adherent

int-snw-1983

Statistics

Genes (10)

Interactions (13)

Related GO terms (112)