int-snw-1213

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	1.138	2.07e-24	1.23e-05	6.06e-04

wolf-screen-ratio-mammosphere-adherent-int-snw-1213 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
RPA2	6118	98	1.250	1.151	69	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
EIF2S2	8894	27	1.075	1.138	81	Yes	-
[ CLTC ]	1213	35	0.884	1.138	247	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-

Interactions (4)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
ACTB	60	CLTC	1213	pp	--	int.I2D: IntAct_Yeast
CLTC	1213	EIF2S2	8894	pp	--	int.I2D: YeastLow
ACTB	60	RPA2	6118	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct

Related GO terms (133)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0044267	cellular protein metabolic process	3.36e-04	1.00e+00	4.190	3	29	474
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	6.93e-04	1.00e+00	10.494	1	1	2
GO:0002176	male germ cell proliferation	6.93e-04	1.00e+00	10.494	1	1	2
GO:0005055	laminin receptor activity	6.93e-04	1.00e+00	10.494	1	1	2
GO:0006407	rRNA export from nucleus	6.93e-04	1.00e+00	10.494	1	1	2
GO:0006413	translational initiation	8.04e-04	1.00e+00	5.461	2	17	131
GO:0061024	membrane organization	9.84e-04	1.00e+00	5.314	2	7	145
GO:0005850	eukaryotic translation initiation factor 2 complex	1.04e-03	1.00e+00	9.909	1	1	3
GO:1900126	negative regulation of hyaluronan biosynthetic process	1.04e-03	1.00e+00	9.909	1	2	3
GO:0071439	clathrin complex	1.04e-03	1.00e+00	9.909	1	2	3
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.39e-03	1.00e+00	9.494	1	1	4
GO:0030686	90S preribosome	1.39e-03	1.00e+00	9.494	1	1	4
GO:0032051	clathrin light chain binding	1.39e-03	1.00e+00	9.494	1	1	4
GO:1903077	negative regulation of protein localization to plasma membrane	1.39e-03	1.00e+00	9.494	1	1	4
GO:0000730	DNA recombinase assembly	1.73e-03	1.00e+00	9.172	1	1	5
GO:2000001	regulation of DNA damage checkpoint	1.73e-03	1.00e+00	9.172	1	1	5
GO:0030130	clathrin coat of trans-Golgi network vesicle	2.08e-03	1.00e+00	8.909	1	3	6
GO:0030957	Tat protein binding	2.08e-03	1.00e+00	8.909	1	3	6
GO:0030118	clathrin coat	2.08e-03	1.00e+00	8.909	1	2	6
GO:0030132	clathrin coat of coated pit	2.42e-03	1.00e+00	8.687	1	2	7
GO:0000028	ribosomal small subunit assembly	2.42e-03	1.00e+00	8.687	1	1	7
GO:0006412	translation	2.45e-03	1.00e+00	4.649	2	20	230
GO:0070688	MLL5-L complex	2.77e-03	1.00e+00	8.494	1	1	8
GO:0010569	regulation of double-strand break repair via homologous recombination	3.46e-03	1.00e+00	8.172	1	1	10
GO:0044822	poly(A) RNA binding	3.50e-03	1.00e+00	3.035	3	49	1056
GO:0031571	mitotic G1 DNA damage checkpoint	3.81e-03	1.00e+00	8.035	1	4	11
GO:0005829	cytosol	3.86e-03	1.00e+00	2.209	4	132	2496
GO:0043234	protein complex	4.00e-03	1.00e+00	4.290	2	18	295
GO:0005662	DNA replication factor A complex	4.50e-03	1.00e+00	7.794	1	1	13
GO:0019901	protein kinase binding	4.61e-03	1.00e+00	4.186	2	21	317
GO:0035267	NuA4 histone acetyltransferase complex	4.84e-03	1.00e+00	7.687	1	4	14
GO:0050998	nitric-oxide synthase binding	5.54e-03	1.00e+00	7.494	1	1	16
GO:0005925	focal adhesion	6.10e-03	1.00e+00	3.978	2	19	366
GO:0035861	site of double-strand break	6.23e-03	1.00e+00	7.324	1	1	18
GO:0006298	mismatch repair	6.92e-03	1.00e+00	7.172	1	3	20
GO:0032201	telomere maintenance via semi-conservative replication	7.26e-03	1.00e+00	7.102	1	5	21
GO:0000718	nucleotide-excision repair, DNA damage removal	7.26e-03	1.00e+00	7.102	1	4	21
GO:0006297	nucleotide-excision repair, DNA gap filling	7.60e-03	1.00e+00	7.035	1	3	22
GO:0030863	cortical cytoskeleton	7.60e-03	1.00e+00	7.035	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	7.60e-03	1.00e+00	7.035	1	4	22
GO:0043044	ATP-dependent chromatin remodeling	7.95e-03	1.00e+00	6.971	1	4	23
GO:0043236	laminin binding	7.95e-03	1.00e+00	6.971	1	1	23
GO:0008135	translation factor activity, nucleic acid binding	8.29e-03	1.00e+00	6.909	1	7	24
GO:0000722	telomere maintenance via recombination	8.64e-03	1.00e+00	6.850	1	5	25
GO:0043022	ribosome binding	9.33e-03	1.00e+00	6.739	1	3	27
GO:0031492	nucleosomal DNA binding	9.33e-03	1.00e+00	6.739	1	4	27
GO:0030669	clathrin-coated endocytic vesicle membrane	9.67e-03	1.00e+00	6.687	1	4	28
GO:0019894	kinesin binding	9.67e-03	1.00e+00	6.687	1	1	28
GO:0033572	transferrin transport	1.04e-02	1.00e+00	6.587	1	5	30
GO:0006271	DNA strand elongation involved in DNA replication	1.04e-02	1.00e+00	6.587	1	7	30
GO:0031623	receptor internalization	1.07e-02	1.00e+00	6.540	1	2	31
GO:0032588	trans-Golgi network membrane	1.17e-02	1.00e+00	6.407	1	2	34
GO:0001895	retina homeostasis	1.17e-02	1.00e+00	6.407	1	1	34
GO:0034332	adherens junction organization	1.24e-02	1.00e+00	6.324	1	1	36
GO:0005515	protein binding	1.27e-02	1.00e+00	1.260	5	184	6024
GO:0051084	'de novo' posttranslational protein folding	1.28e-02	1.00e+00	6.285	1	4	37
GO:0006284	base-excision repair	1.28e-02	1.00e+00	6.285	1	3	37
GO:0070527	platelet aggregation	1.31e-02	1.00e+00	6.246	1	2	38
GO:0016020	membrane	1.32e-02	1.00e+00	2.364	3	90	1681
GO:0022627	cytosolic small ribosomal subunit	1.34e-02	1.00e+00	6.209	1	4	39
GO:0000781	chromosome, telomeric region	1.34e-02	1.00e+00	6.209	1	3	39
GO:0030136	clathrin-coated vesicle	1.45e-02	1.00e+00	6.102	1	4	42
GO:0006892	post-Golgi vesicle-mediated transport	1.48e-02	1.00e+00	6.068	1	3	43
GO:0021762	substantia nigra development	1.52e-02	1.00e+00	6.035	1	2	44
GO:0006283	transcription-coupled nucleotide-excision repair	1.58e-02	1.00e+00	5.971	1	7	46
GO:0003743	translation initiation factor activity	1.69e-02	1.00e+00	5.879	1	8	49
GO:0003684	damaged DNA binding	1.69e-02	1.00e+00	5.879	1	7	49
GO:0003725	double-stranded RNA binding	1.79e-02	1.00e+00	5.794	1	5	52
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	1.82e-02	1.00e+00	5.766	1	5	53
GO:0045216	cell-cell junction organization	1.86e-02	1.00e+00	5.739	1	2	54
GO:0000724	double-strand break repair via homologous recombination	1.89e-02	1.00e+00	5.713	1	3	55
GO:0000723	telomere maintenance	1.93e-02	1.00e+00	5.687	1	6	56
GO:0010467	gene expression	1.96e-02	1.00e+00	3.108	2	59	669
GO:0019903	protein phosphatase binding	2.13e-02	1.00e+00	5.540	1	4	62
GO:0006302	double-strand break repair	2.13e-02	1.00e+00	5.540	1	4	62
GO:0006289	nucleotide-excision repair	2.34e-02	1.00e+00	5.407	1	11	68
GO:0034329	cell junction assembly	2.34e-02	1.00e+00	5.407	1	1	68
GO:0003697	single-stranded DNA binding	2.34e-02	1.00e+00	5.407	1	5	68
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	2.54e-02	1.00e+00	5.285	1	6	74
GO:0008584	male gonad development	2.57e-02	1.00e+00	5.265	1	3	75
GO:0019083	viral transcription	2.78e-02	1.00e+00	5.154	1	10	81
GO:0006898	receptor-mediated endocytosis	2.88e-02	1.00e+00	5.102	1	3	84
GO:0047485	protein N-terminus binding	2.95e-02	1.00e+00	5.068	1	5	86
GO:0006415	translational termination	2.98e-02	1.00e+00	5.051	1	10	87
GO:0016605	PML body	3.01e-02	1.00e+00	5.035	1	3	88
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	3.08e-02	1.00e+00	5.002	1	7	90
GO:0042470	melanosome	3.12e-02	1.00e+00	4.986	1	9	91
GO:0006928	cellular component movement	3.12e-02	1.00e+00	4.986	1	7	91
GO:0005200	structural constituent of cytoskeleton	3.12e-02	1.00e+00	4.986	1	8	91
GO:0001649	osteoblast differentiation	3.15e-02	1.00e+00	4.971	1	6	92
GO:0006414	translational elongation	3.18e-02	1.00e+00	4.955	1	13	93
GO:0070062	extracellular vesicular exosome	3.53e-02	1.00e+00	1.850	3	104	2400
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	3.55e-02	1.00e+00	4.794	1	10	104
GO:0014069	postsynaptic density	3.59e-02	1.00e+00	4.780	1	3	105
GO:0072562	blood microparticle	3.79e-02	1.00e+00	4.700	1	3	111
GO:0030529	ribonucleoprotein complex	3.82e-02	1.00e+00	4.687	1	8	112
GO:0005819	spindle	3.82e-02	1.00e+00	4.687	1	7	112
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	3.89e-02	1.00e+00	4.661	1	11	114
GO:0019058	viral life cycle	3.92e-02	1.00e+00	4.649	1	13	115
GO:0006325	chromatin organization	4.02e-02	1.00e+00	4.612	1	5	118
GO:0006260	DNA replication	4.13e-02	1.00e+00	4.575	1	9	121
GO:0000790	nuclear chromatin	4.39e-02	1.00e+00	4.483	1	9	129
GO:0031982	vesicle	4.46e-02	1.00e+00	4.461	1	9	131
GO:0003735	structural constituent of ribosome	4.66e-02	1.00e+00	4.396	1	10	137
GO:0005654	nucleoplasm	4.83e-02	1.00e+00	2.415	2	76	1082
GO:0006457	protein folding	4.86e-02	1.00e+00	4.334	1	7	143
GO:0000082	G1/S transition of mitotic cell cycle	5.06e-02	1.00e+00	4.275	1	32	149
GO:0005198	structural molecule activity	5.09e-02	1.00e+00	4.265	1	5	150
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	5.59e-02	1.00e+00	4.128	1	7	165
GO:0030424	axon	5.62e-02	1.00e+00	4.119	1	4	166
GO:0006886	intracellular protein transport	5.79e-02	1.00e+00	4.076	1	5	171
GO:0031625	ubiquitin protein ligase binding	6.02e-02	1.00e+00	4.018	1	14	178
GO:0001701	in utero embryonic development	6.78e-02	1.00e+00	3.843	1	8	201
GO:0016071	mRNA metabolic process	7.50e-02	1.00e+00	3.693	1	31	223
GO:0007067	mitotic nuclear division	7.63e-02	1.00e+00	3.668	1	14	227
GO:0016070	RNA metabolic process	8.28e-02	1.00e+00	3.546	1	32	247
GO:0006281	DNA repair	8.73e-02	1.00e+00	3.466	1	18	261
GO:0019899	enzyme binding	9.24e-02	1.00e+00	3.380	1	12	277
GO:0005856	cytoskeleton	9.69e-02	1.00e+00	3.309	1	12	291
GO:0007411	axon guidance	1.06e-01	1.00e+00	3.177	1	13	319
GO:0003723	RNA binding	1.13e-01	1.00e+00	3.076	1	20	342
GO:0007155	cell adhesion	1.22e-01	1.00e+00	2.967	1	6	369
GO:0000278	mitotic cell cycle	1.28e-01	1.00e+00	2.883	1	48	391
GO:0007596	blood coagulation	1.48e-01	1.00e+00	2.664	1	18	455
GO:0016032	viral process	1.72e-01	1.00e+00	2.433	1	55	534
GO:0045087	innate immune response	1.90e-01	1.00e+00	2.275	1	24	596
GO:0005886	plasma membrane	2.20e-01	1.00e+00	1.160	2	45	2582
GO:0005615	extracellular space	2.91e-01	1.00e+00	1.592	1	17	957
GO:0005524	ATP binding	3.76e-01	1.00e+00	1.152	1	60	1298
GO:0046872	metal ion binding	3.78e-01	1.00e+00	1.142	1	25	1307
GO:0005737	cytoplasm	3.91e-01	1.00e+00	0.615	2	110	3767
GO:0005730	nucleolus	4.53e-01	1.00e+00	0.814	1	69	1641
GO:0005634	nucleus	5.05e-01	1.00e+00	0.340	2	136	4559

Wolf-ratios-Mammosphere-Adherent

int-snw-1213

Statistics

Genes (5)

Interactions (4)

Related GO terms (133)