meta-int-snw-112950

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
reg-snw-60	tai-screen-luciferase	4.243	1.88e-19	3.43e-03	4.71e-03	12	5
int-snw-112950	tai-screen-luciferase	6.537	1.50e-144	1.20e-07	1.60e-03	9	6

tai-screen-luciferase-meta-int-snw-112950 subnetwork

Genes (19)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	List-Gonzales GI	Tai-Hits
HES4	57801	19	-4.153	4.450	10	-	-
DMD	1756	15	-4.338	4.243	53	-	-
COPA	1314	48	-9.395	5.672	340	Yes	Yes
TNFRSF8	943	19	-4.106	4.450	15	-	-
HSF1	3297	46	-4.179	5.027	209	-	Yes
CANX	821	17	-1.959	4.504	65	-	-
COPB2	9276	48	-13.168	9.063	41	Yes	Yes
SNTA1	6640	2	2.065	6.537	73	-	-
COPZ1	22818	48	-8.301	9.063	13	Yes	Yes
RB1	5925	21	-2.085	4.707	351	-	-
CDC42	998	44	-6.960	4.707	276	Yes	Yes
MED8	112950	2	1.834	6.537	42	-	-
MRPS12	6183	35	-5.421	5.516	341	Yes	-
SRF	6722	15	1.994	4.243	23	-	-
ACTB	60	15	-1.716	4.243	23	-	-
ARCN1	372	48	-8.232	9.063	118	Yes	Yes
SERBP1	26135	35	-4.612	5.516	106	-	Yes
COPB1	1315	39	-6.221	9.063	118	Yes	Yes
COPG1	22820	12	-5.279	7.138	37	Yes	Yes

Interactions (35)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
TNFRSF8	943	RB1	5925	pd	<	reg.pazar.txt: no annot
ARCN1	372	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
COPZ1	22818	COPG1	22820	pp	--	int.I2D: BioGrid, HPRD, BIND; int.HPRD: in vitro, in vivo, yeast 2-hybrid; int.DIP: MI:0915(physical association)
ACTB	60	CANX	821	pd	<	reg.ITFP.txt: no annot
COPA	1314	RB1	5925	pd	<>	reg.ITFP.txt: no annot
HSF1	3297	SRF	6722	pd	<>	reg.ITFP.txt: no annot
HSF1	3297	SRF	6722	pp	--	int.Yu: muscle
COPB2	9276	COPG1	22820	pp	--	int.I2D: BioGrid
RB1	5925	HES4	57801	pd	>	reg.pazar.txt: no annot
RB1	5925	SERBP1	26135	pd	>	reg.pazar.txt: no annot
ACTB	60	MRPS12	6183	pp	--	int.I2D: BioGrid_Yeast
SNTA1	6640	MED8	112950	pp	--	int.Intact: MI:0915(physical association); int.I2D: HPRD, MINT, StelzlLow, IntAct; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
ARCN1	372	COPG1	22820	pp	--	int.I2D: HPRD; int.HPRD: in vivo
DMD	1756	MED8	112950	pp	--	int.I2D: BioGrid_Fly, FlyLow, IntAct_Fly
COPB1	1315	COPG1	22820	pp	--	int.I2D: BioGrid, HPRD; int.HPRD: in vitro, in vivo, yeast 2-hybrid; int.DIP: MI:0915(physical association)
COPB1	1315	SNTA1	6640	pp	--	int.I2D: INNATEDB
DMD	1756	SNTA1	6640	pp	--	int.I2D: BCI, BioGrid, BIND_Mouse, HPRD, IntAct_Mouse, MINT_Mouse; int.HPRD: in vitro, in vivo
ACTB	60	RB1	5925	pd	<	reg.ITFP.txt: no annot
ACTB	60	COPA	1314	pd	<	reg.ITFP.txt: no annot
ACTB	60	COPA	1314	pp	--	int.I2D: BioGrid_Yeast
COPA	1314	COPB1	1315	pp	--	int.I2D: BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, Krogan_Core, YeastHigh
DMD	1756	SRF	6722	pd	<	reg.pazar.txt: no annot; reg.TRANSFAC.txt: no annot
CANX	821	RB1	5925	pd	<>	reg.ITFP.txt: no annot
COPA	1314	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
CANX	821	MRPS12	6183	pp	--	int.I2D: BioGrid_Yeast
COPA	1314	COPB2	9276	pp	--	int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vivo
COPB1	1315	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastMedium; int.DIP: MI:0915(physical association)
CANX	821	COPA	1314	pd	<>	reg.ITFP.txt: no annot
ACTB	60	ARCN1	372	pp	--	int.I2D: BioGrid_Yeast
HSF1	3297	MRPS12	6183	pd	<>	reg.ITFP.txt: no annot
RB1	5925	MED8	112950	pd	>	reg.pazar.txt: no annot
COPB1	1315	COPB2	9276	pp	--	int.I2D: BioGrid
ARCN1	372	COPB1	1315	pp	--	int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, BIND, BIND_Yeast, HPRD, Krogan_Core, MIPS; int.HPRD: in vivo
ARCN1	372	COPA	1314	pp	--	int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core; int.HPRD: in vivo
CDC42	998	RB1	5925	pd	<	reg.pazar.txt: no annot
ARCN1	372	COPB2	9276	pp	--	int.I2D: HPRD, BCI; int.HPRD: in vivo
ACTB	60	SRF	6722	pd	<	reg.pazar.txt: no annot; reg.oreganno.txt: no annot

Related GO terms (380)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0048205	COPI coating of Golgi vesicle	1.77e-15	2.88e-11	8.631	6	6	13
GO:0030126	COPI vesicle coat	1.77e-15	2.88e-11	8.631	6	6	13
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	1.81e-13	2.95e-09	7.688	6	6	25
GO:0061024	membrane organization	1.83e-10	2.98e-06	5.364	7	11	146
GO:0006886	intracellular protein transport	3.15e-08	5.14e-04	4.897	6	6	173
GO:0050998	nitric-oxide synthase binding	7.42e-07	1.21e-02	7.331	3	3	16
GO:0006891	intra-Golgi vesicle-mediated transport	9.00e-07	1.47e-02	7.244	3	3	17
GO:0051683	establishment of Golgi localization	3.85e-06	6.28e-02	9.162	2	2	3
GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation	3.85e-06	6.28e-02	9.162	2	2	3
GO:0016013	syntrophin complex	7.69e-06	1.26e-01	8.747	2	2	4
GO:0072384	organelle transport along microtubule	7.69e-06	1.26e-01	8.747	2	2	4
GO:0043234	protein complex	1.91e-05	3.12e-01	3.840	5	9	300
GO:0005198	structural molecule activity	3.00e-05	4.90e-01	4.434	4	5	159
GO:0090136	epithelial cell-cell adhesion	4.60e-05	7.51e-01	7.577	2	2	9
GO:0036464	cytoplasmic ribonucleoprotein granule	2.93e-04	1.00e+00	6.287	2	5	22
GO:0002027	regulation of heart rate	5.48e-04	1.00e+00	5.840	2	2	30
GO:0034332	adherens junction organization	7.90e-04	1.00e+00	5.577	2	4	36
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	9.20e-04	1.00e+00	3.939	3	4	168
GO:0030038	contractile actin filament bundle assembly	1.16e-03	1.00e+00	9.747	1	1	1
GO:0045556	positive regulation of TRAIL biosynthetic process	1.16e-03	1.00e+00	9.747	1	1	1
GO:0090287	regulation of cellular response to growth factor stimulus	1.16e-03	1.00e+00	9.747	1	1	1
GO:0021691	cerebellar Purkinje cell layer maturation	1.16e-03	1.00e+00	9.747	1	1	1
GO:0090230	regulation of centromere complex assembly	1.16e-03	1.00e+00	9.747	1	1	1
GO:0046016	positive regulation of transcription by glucose	1.16e-03	1.00e+00	9.747	1	1	1
GO:0003117	regulation of vasoconstriction by circulating norepinephrine	1.16e-03	1.00e+00	9.747	1	1	1
GO:0005829	cytosol	1.17e-03	1.00e+00	1.593	9	74	2562
GO:0034613	cellular protein localization	1.18e-03	1.00e+00	5.287	2	2	44
GO:0021762	substantia nigra development	1.29e-03	1.00e+00	5.223	2	2	46
GO:0016328	lateral plasma membrane	1.29e-03	1.00e+00	5.223	2	3	46
GO:0030175	filopodium	1.71e-03	1.00e+00	5.019	2	2	53
GO:0071338	positive regulation of hair follicle cell proliferation	2.33e-03	1.00e+00	8.747	1	1	2
GO:0060661	submandibular salivary gland formation	2.33e-03	1.00e+00	8.747	1	1	2
GO:0090135	actin filament branching	2.33e-03	1.00e+00	8.747	1	1	2
GO:0014819	regulation of skeletal muscle contraction	2.33e-03	1.00e+00	8.747	1	1	2
GO:0031134	sister chromatid biorientation	2.33e-03	1.00e+00	8.747	1	1	2
GO:0086001	cardiac muscle cell action potential	2.33e-03	1.00e+00	8.747	1	1	2
GO:0010736	serum response element binding	2.33e-03	1.00e+00	8.747	1	1	2
GO:0007070	negative regulation of transcription from RNA polymerase II promoter during mitosis	2.33e-03	1.00e+00	8.747	1	1	2
GO:0016020	membrane	2.50e-03	1.00e+00	1.784	7	48	1746
GO:0008134	transcription factor binding	2.74e-03	1.00e+00	3.389	3	5	246
GO:0042383	sarcolemma	3.04e-03	1.00e+00	4.597	2	2	71
GO:0031175	neuron projection development	3.39e-03	1.00e+00	4.518	2	2	75
GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	3.49e-03	1.00e+00	8.162	1	1	3
GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	3.49e-03	1.00e+00	8.162	1	1	3
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	3.49e-03	1.00e+00	8.162	1	1	3
GO:0060947	cardiac vascular smooth muscle cell differentiation	3.49e-03	1.00e+00	8.162	1	1	3
GO:0003161	cardiac conduction system development	3.49e-03	1.00e+00	8.162	1	1	3
GO:0071459	protein localization to chromosome, centromeric region	3.49e-03	1.00e+00	8.162	1	1	3
GO:0033561	regulation of water loss via skin	3.49e-03	1.00e+00	8.162	1	1	3
GO:1900222	negative regulation of beta-amyloid clearance	3.49e-03	1.00e+00	8.162	1	1	3
GO:1901385	regulation of voltage-gated calcium channel activity	3.49e-03	1.00e+00	8.162	1	1	3
GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle	3.49e-03	1.00e+00	8.162	1	1	3
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	3.57e-03	1.00e+00	4.480	2	4	77
GO:0071922	regulation of cohesin localization to chromatin	4.65e-03	1.00e+00	7.747	1	2	4
GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation	4.65e-03	1.00e+00	7.747	1	1	4
GO:0034191	apolipoprotein A-I receptor binding	4.65e-03	1.00e+00	7.747	1	1	4
GO:0048664	neuron fate determination	4.65e-03	1.00e+00	7.747	1	1	4
GO:0010669	epithelial structure maintenance	4.65e-03	1.00e+00	7.747	1	1	4
GO:0010735	positive regulation of transcription via serum response element binding	4.65e-03	1.00e+00	7.747	1	1	4
GO:0060684	epithelial-mesenchymal cell signaling	4.65e-03	1.00e+00	7.747	1	1	4
GO:0051835	positive regulation of synapse structural plasticity	4.65e-03	1.00e+00	7.747	1	1	4
GO:0043550	regulation of lipid kinase activity	4.65e-03	1.00e+00	7.747	1	1	4
GO:0035189	Rb-E2F complex	4.65e-03	1.00e+00	7.747	1	1	4
GO:0034349	glial cell apoptotic process	4.65e-03	1.00e+00	7.747	1	1	4
GO:0034088	maintenance of mitotic sister chromatid cohesion	4.65e-03	1.00e+00	7.747	1	1	4
GO:0090231	regulation of spindle checkpoint	4.65e-03	1.00e+00	7.747	1	1	4
GO:0005200	structural constituent of cytoskeleton	5.16e-03	1.00e+00	4.207	2	6	93
GO:0005856	cytoskeleton	5.29e-03	1.00e+00	3.051	3	6	311
GO:0036336	dendritic cell migration	5.81e-03	1.00e+00	7.425	1	1	5
GO:0043043	peptide biosynthetic process	5.81e-03	1.00e+00	7.425	1	1	5
GO:2000651	positive regulation of sodium ion transmembrane transporter activity	5.81e-03	1.00e+00	7.425	1	1	5
GO:0035088	establishment or maintenance of apical/basal cell polarity	5.81e-03	1.00e+00	7.425	1	1	5
GO:0048667	cell morphogenesis involved in neuron differentiation	5.81e-03	1.00e+00	7.425	1	1	5
GO:0031256	leading edge membrane	5.81e-03	1.00e+00	7.425	1	1	5
GO:0044233	ER-mitochondrion membrane contact site	5.81e-03	1.00e+00	7.425	1	1	5
GO:0035912	dorsal aorta morphogenesis	5.81e-03	1.00e+00	7.425	1	1	5
GO:0005515	protein binding	6.22e-03	1.00e+00	0.866	13	87	6127
GO:0043353	enucleate erythrocyte differentiation	6.97e-03	1.00e+00	7.162	1	1	6
GO:0007143	female meiotic division	6.97e-03	1.00e+00	7.162	1	1	6
GO:0044458	motile cilium assembly	6.97e-03	1.00e+00	7.162	1	1	6
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	6.97e-03	1.00e+00	7.162	1	1	6
GO:0051150	regulation of smooth muscle cell differentiation	6.97e-03	1.00e+00	7.162	1	1	6
GO:0060789	hair follicle placode formation	6.97e-03	1.00e+00	7.162	1	1	6
GO:0030957	Tat protein binding	6.97e-03	1.00e+00	7.162	1	1	6
GO:0048554	positive regulation of metalloenzyme activity	6.97e-03	1.00e+00	7.162	1	1	6
GO:0005737	cytoplasm	7.31e-03	1.00e+00	1.111	10	65	3976
GO:0007097	nuclear migration	8.12e-03	1.00e+00	6.939	1	2	7
GO:0003334	keratinocyte development	8.12e-03	1.00e+00	6.939	1	1	7
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	8.12e-03	1.00e+00	6.939	1	1	7
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	8.12e-03	1.00e+00	6.939	1	1	7
GO:0002162	dystroglycan binding	8.12e-03	1.00e+00	6.939	1	1	7
GO:0060055	angiogenesis involved in wound healing	8.12e-03	1.00e+00	6.939	1	1	7
GO:0030157	pancreatic juice secretion	8.12e-03	1.00e+00	6.939	1	1	7
GO:0060136	embryonic process involved in female pregnancy	8.12e-03	1.00e+00	6.939	1	1	7
GO:1902305	regulation of sodium ion transmembrane transport	8.12e-03	1.00e+00	6.939	1	1	7
GO:0043497	regulation of protein heterodimerization activity	8.12e-03	1.00e+00	6.939	1	1	7
GO:0008285	negative regulation of cell proliferation	8.36e-03	1.00e+00	2.812	3	3	367
GO:0043589	skin morphogenesis	9.28e-03	1.00e+00	6.747	1	1	8
GO:0090009	primitive streak formation	9.28e-03	1.00e+00	6.747	1	1	8
GO:0070688	MLL5-L complex	9.28e-03	1.00e+00	6.747	1	1	8
GO:0051489	regulation of filopodium assembly	9.28e-03	1.00e+00	6.747	1	1	8
GO:0000790	nuclear chromatin	1.03e-02	1.00e+00	3.691	2	2	133
GO:0097284	hepatocyte apoptotic process	1.04e-02	1.00e+00	6.577	1	1	9
GO:0000983	RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity	1.04e-02	1.00e+00	6.577	1	1	9
GO:0000075	cell cycle checkpoint	1.04e-02	1.00e+00	6.577	1	1	9
GO:0045059	positive thymic T cell selection	1.04e-02	1.00e+00	6.577	1	1	9
GO:0000139	Golgi membrane	1.12e-02	1.00e+00	2.659	3	7	408
GO:0031274	positive regulation of pseudopodium assembly	1.16e-02	1.00e+00	6.425	1	2	10
GO:0001076	RNA polymerase II transcription factor binding transcription factor activity	1.16e-02	1.00e+00	6.425	1	1	10
GO:0061029	eyelid development in camera-type eye	1.16e-02	1.00e+00	6.425	1	1	10
GO:0005798	Golgi-associated vesicle	1.16e-02	1.00e+00	6.425	1	1	10
GO:0060218	hematopoietic stem cell differentiation	1.16e-02	1.00e+00	6.425	1	1	10
GO:0060047	heart contraction	1.16e-02	1.00e+00	6.425	1	1	10
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	1.16e-02	1.00e+00	6.425	1	1	10
GO:0017166	vinculin binding	1.27e-02	1.00e+00	6.287	1	1	11
GO:0042551	neuron maturation	1.27e-02	1.00e+00	6.287	1	1	11
GO:0045651	positive regulation of macrophage differentiation	1.27e-02	1.00e+00	6.287	1	1	11
GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	1.27e-02	1.00e+00	6.287	1	1	11
GO:0045120	pronucleus	1.27e-02	1.00e+00	6.287	1	1	11
GO:0002011	morphogenesis of an epithelial sheet	1.27e-02	1.00e+00	6.287	1	1	11
GO:0006457	protein folding	1.28e-02	1.00e+00	3.527	2	3	149
GO:0072583	clathrin-mediated endocytosis	1.39e-02	1.00e+00	6.162	1	1	12
GO:0051146	striated muscle cell differentiation	1.39e-02	1.00e+00	6.162	1	2	12
GO:0043149	stress fiber assembly	1.39e-02	1.00e+00	6.162	1	2	12
GO:0055003	cardiac myofibril assembly	1.39e-02	1.00e+00	6.162	1	1	12
GO:0042789	mRNA transcription from RNA polymerase II promoter	1.50e-02	1.00e+00	6.046	1	1	13
GO:0043488	regulation of mRNA stability	1.50e-02	1.00e+00	6.046	1	1	13
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	1.50e-02	1.00e+00	6.046	1	1	13
GO:0035855	megakaryocyte development	1.50e-02	1.00e+00	6.046	1	1	13
GO:0035267	NuA4 histone acetyltransferase complex	1.62e-02	1.00e+00	5.939	1	2	14
GO:0031333	negative regulation of protein complex assembly	1.62e-02	1.00e+00	5.939	1	1	14
GO:0031996	thioesterase binding	1.62e-02	1.00e+00	5.939	1	1	14
GO:0034185	apolipoprotein binding	1.62e-02	1.00e+00	5.939	1	1	14
GO:0060292	long term synaptic depression	1.62e-02	1.00e+00	5.939	1	1	14
GO:0048488	synaptic vesicle endocytosis	1.62e-02	1.00e+00	5.939	1	1	14
GO:0030424	axon	1.68e-02	1.00e+00	3.320	2	4	172
GO:0045445	myoblast differentiation	1.73e-02	1.00e+00	5.840	1	1	15
GO:0048821	erythrocyte development	1.73e-02	1.00e+00	5.840	1	2	15
GO:0030131	clathrin adaptor complex	1.73e-02	1.00e+00	5.840	1	1	15
GO:0002042	cell migration involved in sprouting angiogenesis	1.73e-02	1.00e+00	5.840	1	1	15
GO:0030225	macrophage differentiation	1.73e-02	1.00e+00	5.840	1	1	15
GO:0016010	dystrophin-associated glycoprotein complex	1.73e-02	1.00e+00	5.840	1	1	15
GO:0016514	SWI/SNF complex	1.73e-02	1.00e+00	5.840	1	1	15
GO:0051233	spindle midzone	1.73e-02	1.00e+00	5.840	1	2	15
GO:0045987	positive regulation of smooth muscle contraction	1.73e-02	1.00e+00	5.840	1	1	15
GO:0060347	heart trabecula formation	1.73e-02	1.00e+00	5.840	1	1	15
GO:0045211	postsynaptic membrane	1.77e-02	1.00e+00	3.279	2	3	177
GO:0032839	dendrite cytoplasm	1.85e-02	1.00e+00	5.747	1	1	16
GO:0042176	regulation of protein catabolic process	1.85e-02	1.00e+00	5.747	1	4	16
GO:0033137	negative regulation of peptidyl-serine phosphorylation	1.85e-02	1.00e+00	5.747	1	1	16
GO:0030220	platelet formation	1.85e-02	1.00e+00	5.747	1	1	16
GO:0043623	cellular protein complex assembly	1.85e-02	1.00e+00	5.747	1	1	16
GO:0046716	muscle cell cellular homeostasis	1.85e-02	1.00e+00	5.747	1	1	16
GO:0031527	filopodium membrane	1.96e-02	1.00e+00	5.659	1	1	17
GO:0001829	trophectodermal cell differentiation	1.96e-02	1.00e+00	5.659	1	1	17
GO:0035255	ionotropic glutamate receptor binding	1.96e-02	1.00e+00	5.659	1	1	17
GO:0086005	ventricular cardiac muscle cell action potential	1.96e-02	1.00e+00	5.659	1	1	17
GO:0015935	small ribosomal subunit	1.96e-02	1.00e+00	5.659	1	9	17
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	1.96e-02	1.00e+00	5.659	1	1	17
GO:0030742	GTP-dependent protein binding	1.96e-02	1.00e+00	5.659	1	1	17
GO:0008306	associative learning	1.96e-02	1.00e+00	5.659	1	1	17
GO:0017022	myosin binding	2.08e-02	1.00e+00	5.577	1	2	18
GO:0090316	positive regulation of intracellular protein transport	2.08e-02	1.00e+00	5.577	1	1	18
GO:0007088	regulation of mitosis	2.19e-02	1.00e+00	5.499	1	1	19
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	2.19e-02	1.00e+00	5.499	1	1	19
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	2.30e-02	1.00e+00	5.425	1	1	20
GO:0090398	cellular senescence	2.30e-02	1.00e+00	5.425	1	1	20
GO:0043473	pigmentation	2.30e-02	1.00e+00	5.425	1	2	20
GO:0046847	filopodium assembly	2.42e-02	1.00e+00	5.354	1	1	21
GO:0009306	protein secretion	2.42e-02	1.00e+00	5.354	1	2	21
GO:0043034	costamere	2.42e-02	1.00e+00	5.354	1	1	21
GO:0005790	smooth endoplasmic reticulum	2.53e-02	1.00e+00	5.287	1	1	22
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2.53e-02	1.00e+00	5.287	1	1	22
GO:0017080	sodium channel regulator activity	2.53e-02	1.00e+00	5.287	1	1	22
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	2.53e-02	1.00e+00	5.287	1	1	22
GO:0030863	cortical cytoskeleton	2.53e-02	1.00e+00	5.287	1	1	22
GO:0001892	embryonic placenta development	2.65e-02	1.00e+00	5.223	1	1	23
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	2.65e-02	1.00e+00	5.223	1	1	23
GO:0051491	positive regulation of filopodium assembly	2.65e-02	1.00e+00	5.223	1	2	23
GO:0043044	ATP-dependent chromatin remodeling	2.65e-02	1.00e+00	5.223	1	1	23
GO:0002040	sprouting angiogenesis	2.65e-02	1.00e+00	5.223	1	1	23
GO:0045879	negative regulation of smoothened signaling pathway	2.65e-02	1.00e+00	5.223	1	1	23
GO:0051017	actin filament bundle assembly	2.65e-02	1.00e+00	5.223	1	1	23
GO:0005761	mitochondrial ribosome	2.76e-02	1.00e+00	5.162	1	1	24
GO:0007163	establishment or maintenance of cell polarity	2.76e-02	1.00e+00	5.162	1	2	24
GO:0048589	developmental growth	2.99e-02	1.00e+00	5.046	1	1	26
GO:0001707	mesoderm formation	2.99e-02	1.00e+00	5.046	1	1	26
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	2.99e-02	1.00e+00	5.046	1	2	26
GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane	2.99e-02	1.00e+00	5.046	1	1	26
GO:0045214	sarcomere organization	2.99e-02	1.00e+00	5.046	1	1	26
GO:0045859	regulation of protein kinase activity	2.99e-02	1.00e+00	5.046	1	1	26
GO:0031424	keratinization	3.10e-02	1.00e+00	4.992	1	1	27
GO:0051149	positive regulation of muscle cell differentiation	3.10e-02	1.00e+00	4.992	1	2	27
GO:0032720	negative regulation of tumor necrosis factor production	3.10e-02	1.00e+00	4.992	1	1	27
GO:0007616	long-term memory	3.10e-02	1.00e+00	4.992	1	1	27
GO:0048565	digestive tract development	3.10e-02	1.00e+00	4.992	1	1	27
GO:0031069	hair follicle morphogenesis	3.10e-02	1.00e+00	4.992	1	1	27
GO:0032467	positive regulation of cytokinesis	3.21e-02	1.00e+00	4.939	1	1	28
GO:0045597	positive regulation of cell differentiation	3.21e-02	1.00e+00	4.939	1	1	28
GO:0031492	nucleosomal DNA binding	3.21e-02	1.00e+00	4.939	1	1	28
GO:0019894	kinesin binding	3.21e-02	1.00e+00	4.939	1	1	28
GO:0044822	poly(A) RNA binding	3.31e-02	1.00e+00	1.672	4	42	1078
GO:0003730	mRNA 3'-UTR binding	3.32e-02	1.00e+00	4.889	1	1	29
GO:0034605	cellular response to heat	3.32e-02	1.00e+00	4.889	1	1	29
GO:0072686	mitotic spindle	3.32e-02	1.00e+00	4.889	1	1	29
GO:0031647	regulation of protein stability	3.44e-02	1.00e+00	4.840	1	1	30
GO:0007346	regulation of mitotic cell cycle	3.44e-02	1.00e+00	4.840	1	3	30
GO:0040018	positive regulation of multicellular organism growth	3.44e-02	1.00e+00	4.840	1	1	30
GO:0043025	neuronal cell body	3.47e-02	1.00e+00	2.758	2	5	254
GO:0007093	mitotic cell cycle checkpoint	3.55e-02	1.00e+00	4.792	1	2	31
GO:0061077	chaperone-mediated protein folding	3.55e-02	1.00e+00	4.792	1	1	31
GO:0007528	neuromuscular junction development	3.66e-02	1.00e+00	4.747	1	1	32
GO:0051219	phosphoprotein binding	3.66e-02	1.00e+00	4.747	1	4	32
GO:0001104	RNA polymerase II transcription cofactor activity	3.77e-02	1.00e+00	4.702	1	2	33
GO:0070830	tight junction assembly	3.77e-02	1.00e+00	4.702	1	1	33
GO:0001569	patterning of blood vessels	3.89e-02	1.00e+00	4.659	1	1	34
GO:0042692	muscle cell differentiation	3.89e-02	1.00e+00	4.659	1	2	34
GO:0016592	mediator complex	4.00e-02	1.00e+00	4.617	1	2	35
GO:0048666	neuron development	4.00e-02	1.00e+00	4.617	1	1	35
GO:0071333	cellular response to glucose stimulus	4.00e-02	1.00e+00	4.617	1	2	35
GO:0009725	response to hormone	4.00e-02	1.00e+00	4.617	1	1	35
GO:0003779	actin binding	4.01e-02	1.00e+00	2.643	2	3	275
GO:0051402	neuron apoptotic process	4.11e-02	1.00e+00	4.577	1	1	36
GO:0001895	retina homeostasis	4.11e-02	1.00e+00	4.577	1	1	36
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	4.11e-02	1.00e+00	4.577	1	3	36
GO:0001102	RNA polymerase II activating transcription factor binding	4.22e-02	1.00e+00	4.537	1	1	37
GO:0051084	'de novo' posttranslational protein folding	4.22e-02	1.00e+00	4.537	1	2	37
GO:0005791	rough endoplasmic reticulum	4.22e-02	1.00e+00	4.537	1	1	37
GO:0030049	muscle filament sliding	4.33e-02	1.00e+00	4.499	1	2	38
GO:0045740	positive regulation of DNA replication	4.33e-02	1.00e+00	4.499	1	1	38
GO:0070527	platelet aggregation	4.33e-02	1.00e+00	4.499	1	1	38
GO:0050681	androgen receptor binding	4.33e-02	1.00e+00	4.499	1	2	38
GO:0021766	hippocampus development	4.45e-02	1.00e+00	4.461	1	3	39
GO:0031490	chromatin DNA binding	4.45e-02	1.00e+00	4.461	1	1	39
GO:0060048	cardiac muscle contraction	4.45e-02	1.00e+00	4.461	1	1	39
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	4.56e-02	1.00e+00	4.425	1	1	40
GO:0051117	ATPase binding	4.67e-02	1.00e+00	4.389	1	2	41
GO:0008307	structural constituent of muscle	4.67e-02	1.00e+00	4.389	1	1	41
GO:0030521	androgen receptor signaling pathway	4.67e-02	1.00e+00	4.389	1	3	41
GO:0035914	skeletal muscle cell differentiation	4.78e-02	1.00e+00	4.354	1	1	42
GO:0030155	regulation of cell adhesion	4.78e-02	1.00e+00	4.354	1	1	42
GO:0001047	core promoter binding	5.22e-02	1.00e+00	4.223	1	1	46
GO:0043525	positive regulation of neuron apoptotic process	5.22e-02	1.00e+00	4.223	1	2	46
GO:0031594	neuromuscular junction	5.22e-02	1.00e+00	4.223	1	1	46
GO:0019901	protein kinase binding	5.26e-02	1.00e+00	2.425	2	9	320
GO:0008344	adult locomotory behavior	5.33e-02	1.00e+00	4.192	1	2	47
GO:0003700	sequence-specific DNA binding transcription factor activity	5.38e-02	1.00e+00	1.785	3	9	748
GO:0007411	axon guidance	5.47e-02	1.00e+00	2.393	2	3	327
GO:0001947	heart looping	5.56e-02	1.00e+00	4.132	1	1	49
GO:0043231	intracellular membrane-bounded organelle	5.62e-02	1.00e+00	2.371	2	3	332
GO:0007030	Golgi organization	5.67e-02	1.00e+00	4.103	1	3	50
GO:0034097	response to cytokine	5.67e-02	1.00e+00	4.103	1	1	50
GO:0001948	glycoprotein binding	5.67e-02	1.00e+00	4.103	1	2	50
GO:0006952	defense response	6.00e-02	1.00e+00	4.019	1	1	53
GO:0070062	extracellular vesicular exosome	6.00e-02	1.00e+00	1.035	6	51	2516
GO:0019900	kinase binding	6.11e-02	1.00e+00	3.992	1	3	54
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	6.11e-02	1.00e+00	3.992	1	1	54
GO:0050680	negative regulation of epithelial cell proliferation	6.11e-02	1.00e+00	3.992	1	1	54
GO:0046330	positive regulation of JNK cascade	6.22e-02	1.00e+00	3.965	1	1	55
GO:0030054	cell junction	6.36e-02	1.00e+00	2.271	2	4	356
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	6.43e-02	1.00e+00	3.914	1	1	57
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	6.55e-02	1.00e+00	1.668	3	11	811
GO:0005840	ribosome	6.65e-02	1.00e+00	3.864	1	10	59
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	6.65e-02	1.00e+00	3.864	1	1	59
GO:0045216	cell-cell junction organization	6.65e-02	1.00e+00	3.864	1	2	59
GO:0010976	positive regulation of neuron projection development	6.76e-02	1.00e+00	3.840	1	2	60
GO:0005925	focal adhesion	6.80e-02	1.00e+00	2.215	2	23	370
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	6.87e-02	1.00e+00	3.816	1	1	61
GO:0033138	positive regulation of peptidyl-serine phosphorylation	6.87e-02	1.00e+00	3.816	1	1	61
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	6.98e-02	1.00e+00	3.792	1	1	62
GO:0006469	negative regulation of protein kinase activity	7.31e-02	1.00e+00	3.724	1	1	65
GO:0009636	response to toxic substance	7.41e-02	1.00e+00	3.702	1	1	66
GO:0071260	cellular response to mechanical stimulus	7.41e-02	1.00e+00	3.702	1	3	66
GO:0031295	T cell costimulation	7.52e-02	1.00e+00	3.680	1	3	67
GO:0030141	secretory granule	7.52e-02	1.00e+00	3.680	1	2	67
GO:0006338	chromatin remodeling	7.63e-02	1.00e+00	3.659	1	2	68
GO:0045666	positive regulation of neuron differentiation	7.63e-02	1.00e+00	3.659	1	1	68
GO:0035264	multicellular organism growth	7.85e-02	1.00e+00	3.617	1	1	70
GO:0034329	cell junction assembly	7.95e-02	1.00e+00	3.597	1	2	71
GO:0000785	chromatin	8.17e-02	1.00e+00	3.557	1	2	73
GO:0060070	canonical Wnt signaling pathway	8.38e-02	1.00e+00	3.518	1	2	75
GO:0007265	Ras protein signal transduction	8.38e-02	1.00e+00	3.518	1	3	75
GO:0044325	ion channel binding	8.60e-02	1.00e+00	3.480	1	3	77
GO:0010629	negative regulation of gene expression	8.92e-02	1.00e+00	3.425	1	2	80
GO:0045177	apical part of cell	9.13e-02	1.00e+00	3.389	1	1	82
GO:0030336	negative regulation of cell migration	9.24e-02	1.00e+00	3.371	1	2	83
GO:0007517	muscle organ development	9.24e-02	1.00e+00	3.371	1	1	83
GO:0043197	dendritic spine	9.24e-02	1.00e+00	3.371	1	2	83
GO:0005179	hormone activity	9.34e-02	1.00e+00	3.354	1	1	84
GO:0007160	cell-matrix adhesion	9.77e-02	1.00e+00	3.287	1	1	88
GO:0006936	muscle contraction	9.77e-02	1.00e+00	3.287	1	1	88
GO:0007596	blood coagulation	1.00e-01	1.00e+00	1.889	2	5	464
GO:0018279	protein N-linked glycosylation via asparagine	1.01e-01	1.00e+00	3.239	1	1	91
GO:0016605	PML body	1.02e-01	1.00e+00	3.223	1	2	92
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	1.02e-01	1.00e+00	3.223	1	3	92
GO:0042470	melanosome	1.02e-01	1.00e+00	3.223	1	2	92
GO:0006928	cellular component movement	1.02e-01	1.00e+00	3.223	1	4	92
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	1.03e-01	1.00e+00	3.207	1	1	93
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.04e-01	1.00e+00	3.192	1	7	94
GO:0051082	unfolded protein binding	1.05e-01	1.00e+00	3.177	1	1	95
GO:0030165	PDZ domain binding	1.05e-01	1.00e+00	3.177	1	1	95
GO:0001764	neuron migration	1.06e-01	1.00e+00	3.162	1	2	96
GO:0042802	identical protein binding	1.10e-01	1.00e+00	1.807	2	4	491
GO:0044267	cellular protein metabolic process	1.12e-01	1.00e+00	1.795	2	29	495
GO:0004888	transmembrane signaling receptor activity	1.13e-01	1.00e+00	3.060	1	1	103
GO:0014069	postsynaptic density	1.17e-01	1.00e+00	3.019	1	3	106
GO:0030496	midbody	1.20e-01	1.00e+00	2.978	1	4	109
GO:0005815	microtubule organizing center	1.21e-01	1.00e+00	2.965	1	4	110
GO:0030529	ribonucleoprotein complex	1.25e-01	1.00e+00	2.914	1	8	114
GO:0005819	spindle	1.25e-01	1.00e+00	2.914	1	4	114
GO:0072562	blood microparticle	1.27e-01	1.00e+00	2.889	1	1	116
GO:0016032	viral process	1.29e-01	1.00e+00	1.670	2	37	540
GO:0005654	nucleoplasm	1.31e-01	1.00e+00	1.235	3	26	1095
GO:0032496	response to lipopolysaccharide	1.33e-01	1.00e+00	2.816	1	1	122
GO:0006325	chromatin organization	1.34e-01	1.00e+00	2.804	1	2	123
GO:0051056	regulation of small GTPase mediated signal transduction	1.34e-01	1.00e+00	2.804	1	3	123
GO:0007568	aging	1.34e-01	1.00e+00	2.804	1	2	123
GO:0007050	cell cycle arrest	1.37e-01	1.00e+00	2.769	1	2	126
GO:0030036	actin cytoskeleton organization	1.40e-01	1.00e+00	2.735	1	3	129
GO:0046983	protein dimerization activity	1.42e-01	1.00e+00	2.713	1	3	131
GO:0005509	calcium ion binding	1.49e-01	1.00e+00	1.544	2	4	589
GO:0003735	structural constituent of ribosome	1.52e-01	1.00e+00	2.607	1	24	141
GO:0007507	heart development	1.52e-01	1.00e+00	2.607	1	1	141
GO:0005911	cell-cell junction	1.53e-01	1.00e+00	2.597	1	2	142
GO:0005783	endoplasmic reticulum	1.57e-01	1.00e+00	1.494	2	6	610
GO:0045087	innate immune response	1.60e-01	1.00e+00	1.480	2	11	616
GO:0010628	positive regulation of gene expression	1.60e-01	1.00e+00	2.527	1	4	149
GO:0001666	response to hypoxia	1.61e-01	1.00e+00	2.518	1	1	150
GO:0000082	G1/S transition of mitotic cell cycle	1.61e-01	1.00e+00	2.518	1	11	150
GO:0030246	carbohydrate binding	1.62e-01	1.00e+00	2.508	1	1	151
GO:0042981	regulation of apoptotic process	1.62e-01	1.00e+00	2.508	1	7	151
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	1.62e-01	1.00e+00	2.508	1	2	151
GO:0005788	endoplasmic reticulum lumen	1.68e-01	1.00e+00	2.452	1	2	157
GO:0043005	neuron projection	1.72e-01	1.00e+00	2.416	1	6	161
GO:0045121	membrane raft	1.72e-01	1.00e+00	2.416	1	3	161
GO:0005516	calmodulin binding	1.73e-01	1.00e+00	2.407	1	3	162
GO:0005794	Golgi apparatus	1.74e-01	1.00e+00	1.402	2	8	650
GO:0031625	ubiquitin protein ligase binding	1.90e-01	1.00e+00	2.255	1	4	180
GO:0043687	post-translational protein modification	1.91e-01	1.00e+00	2.247	1	1	181
GO:0015629	actin cytoskeleton	1.93e-01	1.00e+00	2.231	1	3	183
GO:0006367	transcription initiation from RNA polymerase II promoter	1.94e-01	1.00e+00	2.223	1	5	184
GO:0007173	epidermal growth factor receptor signaling pathway	2.01e-01	1.00e+00	2.169	1	5	191
GO:0003924	GTPase activity	2.12e-01	1.00e+00	2.081	1	6	203
GO:0030168	platelet activation	2.14e-01	1.00e+00	2.067	1	4	205
GO:0005886	plasma membrane	2.24e-01	1.00e+00	0.600	5	24	2834
GO:0006184	GTP catabolic process	2.27e-01	1.00e+00	1.965	1	6	220
GO:0005622	intracellular	2.33e-01	1.00e+00	1.926	1	1	226
GO:0006412	translation	2.41e-01	1.00e+00	1.870	1	29	235
GO:0003713	transcription coactivator activity	2.45e-01	1.00e+00	1.846	1	6	239
GO:0007399	nervous system development	2.50e-01	1.00e+00	1.810	1	1	245
GO:0043065	positive regulation of apoptotic process	2.75e-01	1.00e+00	1.648	1	6	274
GO:0006357	regulation of transcription from RNA polymerase II promoter	2.76e-01	1.00e+00	1.643	1	2	275
GO:0007283	spermatogenesis	2.77e-01	1.00e+00	1.638	1	2	276
GO:0006351	transcription, DNA-templated	2.79e-01	1.00e+00	0.701	3	17	1585
GO:0007264	small GTPase mediated signal transduction	2.89e-01	1.00e+00	1.567	1	7	290
GO:0030198	extracellular matrix organization	2.93e-01	1.00e+00	1.542	1	1	295
GO:0016567	protein ubiquitination	2.96e-01	1.00e+00	1.523	1	3	299
GO:0030154	cell differentiation	3.18e-01	1.00e+00	1.402	1	3	325
GO:0005525	GTP binding	3.20e-01	1.00e+00	1.389	1	6	328
GO:0003682	chromatin binding	3.25e-01	1.00e+00	1.363	1	4	334
GO:0005615	extracellular space	3.31e-01	1.00e+00	0.766	2	3	1010
GO:0000278	mitotic cell cycle	3.75e-01	1.00e+00	1.110	1	16	398
GO:0009986	cell surface	3.92e-01	1.00e+00	1.025	1	1	422
GO:0045892	negative regulation of transcription, DNA-templated	3.94e-01	1.00e+00	1.019	1	2	424
GO:0006366	transcription from RNA polymerase II promoter	3.94e-01	1.00e+00	1.015	1	3	425
GO:0006468	protein phosphorylation	4.24e-01	1.00e+00	0.879	1	6	467
GO:0045893	positive regulation of transcription, DNA-templated	4.38e-01	1.00e+00	0.819	1	8	487
GO:0048471	perinuclear region of cytoplasm	4.62e-01	1.00e+00	0.716	1	9	523
GO:0003677	DNA binding	4.74e-01	1.00e+00	0.347	2	14	1351
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	5.03e-01	1.00e+00	0.544	1	9	589
GO:0005634	nucleus	5.10e-01	1.00e+00	0.094	6	66	4828
GO:0042803	protein homodimerization activity	5.19e-01	1.00e+00	0.477	1	4	617
GO:0005789	endoplasmic reticulum membrane	5.30e-01	1.00e+00	0.434	1	3	636
GO:0010467	gene expression	5.49e-01	1.00e+00	0.361	1	36	669
GO:0007165	signal transduction	6.80e-01	1.00e+00	-0.145	1	7	950
GO:0008270	zinc ion binding	7.23e-01	1.00e+00	-0.313	1	7	1067
GO:0006355	regulation of transcription, DNA-templated	7.36e-01	1.00e+00	-0.362	1	10	1104
GO:0005524	ATP binding	8.07e-01	1.00e+00	-0.656	1	19	1354
GO:0005730	nucleolus	8.74e-01	1.00e+00	-0.971	1	36	1684
GO:0016021	integral component of membrane	9.57e-01	1.00e+00	-1.531	1	4	2483

Tai-Luciferase

meta-int-snw-112950

Interacting subnets

Genes (19)

Interactions (35)

Related GO terms (380)