PLK1

Genes (1)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree List-Gonzales GI Tai-Hits
PLK1 5347 2-3.6906.189217Yes-

Gene info in the NCBI database: PLK1

Subnetworks (2)

Subnetwork ID tai-screen-luciferase score Size Highlighted genes
int-snw-80198 6.184 25 20
int-snw-5706 6.189 25 21

Related GO terms (58)

Accession number Name Occurrences in all snw genes Occurrences in all int/reg genes
GO:0008283cell proliferation4328
GO:0005813centrosome5326
GO:0005515protein binding626024
GO:0005737cytoplasm433767
GO:0010997anaphase-promoting complex binding13
GO:0010800positive regulation of peptidyl-threonine phosphorylation117
GO:0007091metaphase/anaphase transition of mitotic cell cycle17
GO:0000278mitotic cell cycle11391
GO:0001578microtubule bundle formation120
GO:0045184establishment of protein localization227
GO:0005829cytosol612496
GO:0000910cytokinesis251
GO:0043066negative regulation of apoptotic process13424
GO:0019901protein kinase binding6317
GO:0005876spindle microtubule134
GO:0005819spindle2112
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle870
GO:0000776kinetochore263
GO:0004672protein kinase activity4177
GO:0045862positive regulation of proteolysis121
GO:0016301kinase activity233
GO:0007067mitotic nuclear division5227
GO:0007094mitotic spindle assembly checkpoint131
GO:0005730nucleolus241641
GO:0018105peptidyl-serine phosphorylation469
GO:0000281mitotic cytokinesis121
GO:0005654nucleoplasm151082
GO:0051726regulation of cell cycle197
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process144
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process879
GO:0007346regulation of mitotic cell cycle229
GO:0031648protein destabilization121
GO:0015630microtubule cytoskeleton3110
GO:0000922spindle pole387
GO:0007092activation of mitotic anaphase-promoting complex activity12
GO:0051233spindle midzone215
GO:0046677response to antibiotic131
GO:0007077mitotic nuclear envelope disassembly136
GO:0008017microtubule binding1147
GO:0000070mitotic sister chromatid segregation119
GO:0004674protein serine/threonine kinase activity5308
GO:0016567protein ubiquitination3295
GO:0071168protein localization to chromatin15
GO:0006468protein phosphorylation6460
GO:0043393regulation of protein binding220
GO:0005524ATP binding151298
GO:0000942condensed nuclear chromosome outer kinetochore13
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle874
GO:0030496midbody2108
GO:0045736negative regulation of cyclin-dependent protein serine/threonine kinase activity119
GO:0030071regulation of mitotic metaphase/anaphase transition15
GO:0005634nucleus434559
GO:0000086G2/M transition of mitotic cell cycle5136
GO:0031572G2 DNA damage checkpoint119
GO:0000122negative regulation of transcription from RNA polymerase II promoter7570
GO:0051297centrosome organization222
GO:0051443positive regulation of ubiquitin-protein transferase activity112
GO:0040038polar body extrusion after meiotic divisions12