int-snw-80198

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
tai-screen-luciferase 6.184 8.76e-127 1.24e-06 4.42e-03
tai-screen-luciferase-int-snw-80198 subnetwork

Genes (25)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree List-Gonzales GI Tai-Hits
PLK1 5347 2-3.6906.189217Yes-
RPS20 6224 4-4.7576.314153Yes-
RPS8 6202 10-5.5457.555234--
CHMP2A 27243 10-9.0377.55541YesYes
COPA 1314 32-9.3959.063170YesYes
RPS24 6229 21-7.0348.389217Yes-
RPS9 6203 18-7.1277.555140Yes-
COPB2 9276 32-13.1689.06341YesYes
PRIM1 5557 1-3.0356.18453--
RPS4X 6191 18-6.7477.555263Yes-
COPZ1 22818 32-8.3019.06313YesYes
RPS15A 6210 8-5.4137.555177Yes-
CDC42 998 11-6.9608.389265YesYes
RAD51 5888 12.9956.184189Yes-
[ MUS81 ] 80198 1-2.5166.18466--
RPS27A 6233 15-5.6318.389342Yes-
RPS11 6205 17-6.5887.555175Yes-
RPS6 6194 17-5.6038.046208Yes-
GPI 2821 2-4.1307.18957--
UBB 7314 3-4.2896.428147--
SGOL1 151648 1-4.1186.18430Yes-
RPS26 6231 17-7.4788.04660Yes-
ARCN1 372 32-8.2329.063118YesYes
COPB1 1315 22-6.2219.063118YesYes
RPS13 6207 17-6.5897.555174Yes-

Interactions (61)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
RPS9 6203 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RAD51 5888 MUS81 80198 pp -- int.I2D: BioGrid_Yeast
CDC42 998 RPS27A 6233 pp -- int.I2D: SOURAV_MAPK_HIGH
RPS4X 6191 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
GPI 2821 RPS27A 6233 pp -- int.I2D: Krogan_NonCore
RPS8 6202 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
PRIM1 5557 RAD51 5888 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
COPA 1314 COPB2 9276 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vivo
RPS6 6194 RPS27A 6233 pp -- int.I2D: YeastLow
GPI 2821 RPS13 6207 pp -- int.I2D: IntAct_Yeast
RPS8 6202 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 RPS20 6224 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
CDC42 998 UBB 7314 pp -- int.I2D: SOURAV_MAPK_HIGH
RPS4X 6191 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS27A 6233 pp -- int.I2D: YeastLow
RPS13 6207 RPS20 6224 pp -- int.I2D: BioGrid_Yeast
RPS20 6224 RPS26 6231 pp -- int.I2D: YeastLow
ARCN1 372 COPB1 1315 pp -- int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, BIND, BIND_Yeast, HPRD, Krogan_Core, MIPS;
int.HPRD: in vivo
RPS6 6194 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
PLK1 5347 RPS27A 6233 pp -- int.I2D: YeastLow
ARCN1 372 COPB2 9276 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vivo
RPS8 6202 CHMP2A 27243 pp -- int.I2D: BioGrid_Yeast
PRIM1 5557 MUS81 80198 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS24 6229 RPS27A 6233 pp -- int.I2D: YeastMedium
COPB1 1315 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastMedium;
int.DIP: MI:0915(physical association)
RPS9 6203 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
PLK1 5347 MUS81 80198 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
RPS27A 6233 UBB 7314 pp -- int.I2D: BIND
RPS27A 6233 MUS81 80198 pp -- int.I2D: IntAct_Yeast, YeastLow
COPA 1314 COPB1 1315 pp -- int.I2D: BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, Krogan_Core, YeastHigh
RPS9 6203 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS20 6224 pp -- int.I2D: YeastLow
RPS4X 6191 RPS8 6202 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPA 1314 pp -- int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core;
int.HPRD: in vivo
PLK1 5347 RPS8 6202 pp -- int.I2D: BioGrid_Fly, FlyEmbryo, IntAct_Fly
RPS9 6203 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS8 6202 pp -- int.I2D: BioGrid_Yeast, YeastLow
COPA 1314 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
RPS11 6205 RPS20 6224 pp -- int.I2D: YeastMedium, INTEROLOG
RPS4X 6191 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS15A 6210 RPS20 6224 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastHigh, YeastMedium
PLK1 5347 SGOL1 151648 pp -- int.I2D: BioGrid
RPS8 6202 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS26 6231 pp -- int.I2D: YeastLow
COPA 1314 RPS27A 6233 pp -- int.I2D: YeastLow
RPS11 6205 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS20 6224 RPS27A 6233 pp -- int.I2D: YeastLow
COPB1 1315 COPB2 9276 pp -- int.I2D: BioGrid
RPS4X 6191 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast, YeastMedium, INTEROLOG

Related GO terms (356)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0022627cytosolic small ribosomal subunit5.20e-237.50e-197.346112039
GO:0019058viral life cycle1.26e-211.81e-176.0271323115
GO:0019083viral transcription3.62e-195.22e-156.292112081
GO:0006415translational termination8.32e-191.20e-146.189112087
GO:0006414translational elongation1.80e-182.60e-146.093112093
GO:0006614SRP-dependent cotranslational protein targeting to membrane6.53e-189.41e-145.9311120104
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.87e-172.69e-135.7991120114
GO:0006413translational initiation9.06e-171.31e-125.5981121131
GO:0003735structural constituent of ribosome1.50e-162.17e-125.5341122137
GO:0016071mRNA metabolic process6.04e-168.72e-124.9561225223
GO:0016070RNA metabolic process2.08e-153.00e-114.8091225247
GO:0005829cytosol2.16e-143.12e-102.34622612496
GO:0016032viral process2.36e-143.40e-103.9191433534
GO:0006412translation4.89e-147.05e-104.7861123230
GO:0016020membrane3.11e-124.48e-082.62718411681
GO:0030126COPI vesicle coat8.03e-121.16e-077.9095712
GO:0048205COPI coating of Golgi vesicle1.30e-111.88e-077.7945813
GO:0015935small ribosomal subunit6.24e-119.00e-077.4075917
GO:0061024membrane organization8.04e-111.16e-064.992812145
GO:0044267cellular protein metabolic process1.27e-101.83e-063.7431123474
GO:0010467gene expression2.68e-103.87e-063.3711229669
GO:0006890retrograde vesicle-mediated transport, Golgi to ER5.31e-107.65e-066.8505825
GO:0044822poly(A) RNA binding4.74e-086.84e-042.71312321056
GO:0005840ribosome2.80e-064.03e-025.3144858
GO:0006891intra-Golgi vesicle-mediated transport3.08e-064.44e-026.6703417
GO:0036464cytoplasmic ribonucleoprotein granule6.93e-061.00e-016.2983322
GO:0070062extracellular vesicular exosome8.57e-061.24e-011.75114402400
GO:0006886intracellular protein transport9.69e-061.40e-014.07657171
GO:0019843rRNA binding1.31e-051.89e-016.0023427
GO:0000462maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2.88e-054.15e-017.850235
GO:0033119negative regulation of RNA splicing2.88e-054.15e-017.850225
GO:0005925focal adhesion3.02e-054.35e-013.241619366
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway3.16e-054.56e-015.5873336
GO:0030529ribonucleoprotein complex3.84e-055.54e-014.36547112
GO:0000082G1/S transition of mitotic cell cycle1.17e-041.00e+003.95349149
GO:0016197endosomal transport1.27e-041.00e+004.9243357
GO:0042274ribosomal small subunit biogenesis1.88e-041.00e+006.5872612
GO:0019082viral protein processing1.88e-041.00e+006.5872212
GO:0032479regulation of type I interferon production2.22e-041.00e+006.4722213
GO:0005730nucleolus2.30e-041.00e+001.81410241641
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.33e-041.00e+004.6283870
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.75e-041.00e+004.5483874
GO:0051233spindle midzone2.99e-041.00e+006.2652215
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process3.34e-041.00e+004.4533879
GO:0005737cytoplasm3.57e-041.00e+001.20015433767
GO:0075733intracellular transport of virus3.86e-041.00e+006.0852317
GO:0019068virion assembly3.86e-041.00e+006.0852217
GO:0000278mitotic cell cycle4.84e-041.00e+002.883511391
GO:0007220Notch receptor processing6.52e-041.00e+005.7132222
GO:0005844polysome7.14e-041.00e+005.6492223
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway8.44e-041.00e+005.5282225
GO:0005978glycogen biosynthetic process9.14e-041.00e+005.4722226
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia9.14e-041.00e+005.4722226
GO:0006281DNA repair9.83e-041.00e+003.14444261
GO:0045184establishment of protein localization9.86e-041.00e+005.4172227
GO:0006006glucose metabolic process1.08e-031.00e+003.87533118
GO:0032480negative regulation of type I interferon production1.39e-031.00e+005.1722232
GO:0000086G2/M transition of mitotic cell cycle1.62e-031.00e+003.67035136
GO:0022605oogenesis stage1.73e-031.00e+009.172111
GO:0004347glucose-6-phosphate isomerase activity1.73e-031.00e+009.172111
GO:0019242methylglyoxal biosynthetic process1.73e-031.00e+009.172111
GO:0021691cerebellar Purkinje cell layer maturation1.73e-031.00e+009.172111
GO:0043142single-stranded DNA-dependent ATPase activity1.73e-031.00e+009.172111
GO:0016866intramolecular transferase activity1.73e-031.00e+009.172111
GO:0005198structural molecule activity2.14e-031.00e+003.52836150
GO:0007249I-kappaB kinase/NF-kappaB signaling2.27e-031.00e+004.8152341
GO:0043005neuron projection2.44e-031.00e+003.46336157
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway2.49e-031.00e+004.7462243
GO:0007254JNK cascade3.23e-031.00e+004.5582349
GO:0071338positive regulation of hair follicle cell proliferation3.46e-031.00e+008.172112
GO:0030892mitotic cohesin complex3.46e-031.00e+008.172112
GO:0046185aldehyde catabolic process3.46e-031.00e+008.172112
GO:0007092activation of mitotic anaphase-promoting complex activity3.46e-031.00e+008.172112
GO:0040038polar body extrusion after meiotic divisions3.46e-031.00e+008.172112
GO:0060661submandibular salivary gland formation3.46e-031.00e+008.172112
GO:1902255positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator3.46e-031.00e+008.172112
GO:1990077primosome complex3.46e-031.00e+008.172112
GO:00482573'-flap endonuclease activity3.46e-031.00e+008.172112
GO:0090135actin filament branching3.46e-031.00e+008.172112
GO:0072757cellular response to camptothecin3.46e-031.00e+008.172112
GO:0030666endocytic vesicle membrane3.77e-031.00e+004.4442253
GO:0051403stress-activated MAPK cascade3.91e-031.00e+004.4172354
GO:0007173epidermal growth factor receptor signaling pathway4.12e-031.00e+003.19534189
GO:0032481positive regulation of type I interferon production4.96e-031.00e+004.2412361
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway4.96e-031.00e+004.2412261
GO:0051106positive regulation of DNA ligation5.19e-031.00e+007.587113
GO:0051683establishment of Golgi localization5.19e-031.00e+007.587123
GO:0034191apolipoprotein A-I receptor binding5.19e-031.00e+007.587113
GO:0003161cardiac conduction system development5.19e-031.00e+007.587113
GO:0010997anaphase-promoting complex binding5.19e-031.00e+007.587113
GO:0000942condensed nuclear chromosome outer kinetochore5.19e-031.00e+007.587113
GO:0045132meiotic chromosome segregation5.19e-031.00e+007.587113
GO:0000776kinetochore5.28e-031.00e+004.1952263
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest5.44e-031.00e+004.1722664
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle5.61e-031.00e+004.1502665
GO:0006310DNA recombination5.61e-031.00e+004.1502265
GO:0034166toll-like receptor 10 signaling pathway5.61e-031.00e+004.1502465
GO:0034146toll-like receptor 5 signaling pathway5.61e-031.00e+004.1502465
GO:0043066negative regulation of apoptotic process5.71e-031.00e+002.444413424
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway6.66e-031.00e+004.0222471
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway6.66e-031.00e+004.0222471
GO:0007067mitotic nuclear division6.85e-031.00e+002.93135227
GO:0034162toll-like receptor 9 signaling pathway6.85e-031.00e+004.0022472
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent6.85e-031.00e+004.0022672
GO:0003729mRNA binding6.85e-031.00e+004.0022272
GO:0072429response to intra-S DNA damage checkpoint signaling6.92e-031.00e+007.172114
GO:0048664neuron fate determination6.92e-031.00e+007.172114
GO:0060684epithelial-mesenchymal cell signaling6.92e-031.00e+007.172114
GO:0051835positive regulation of synapse structural plasticity6.92e-031.00e+007.172114
GO:0072384organelle transport along microtubule6.92e-031.00e+007.172124
GO:0003896DNA primase activity6.92e-031.00e+007.172114
GO:0034134toll-like receptor 2 signaling pathway7.03e-031.00e+003.9822473
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I7.41e-031.00e+003.9432675
GO:0035666TRIF-dependent toll-like receptor signaling pathway7.60e-031.00e+003.9242476
GO:0002756MyD88-independent toll-like receptor signaling pathway7.99e-031.00e+003.8872478
GO:0034138toll-like receptor 3 signaling pathway8.19e-031.00e+003.8682479
GO:0002755MyD88-dependent toll-like receptor signaling pathway8.39e-031.00e+003.8502480
GO:0036336dendritic cell migration8.64e-031.00e+006.850115
GO:0030071regulation of mitotic metaphase/anaphase transition8.64e-031.00e+006.850115
GO:0000779condensed chromosome, centromeric region8.64e-031.00e+006.850115
GO:0010457centriole-centriole cohesion8.64e-031.00e+006.850115
GO:0035088establishment or maintenance of apical/basal cell polarity8.64e-031.00e+006.850115
GO:0006269DNA replication, synthesis of RNA primer8.64e-031.00e+006.850115
GO:0006312mitotic recombination8.64e-031.00e+006.850115
GO:1902188positive regulation of viral release from host cell8.64e-031.00e+006.850115
GO:0071168protein localization to chromatin8.64e-031.00e+006.850115
GO:0031256leading edge membrane8.64e-031.00e+006.850115
GO:0000730DNA recombinase assembly8.64e-031.00e+006.850115
GO:0005975carbohydrate metabolic process9.22e-031.00e+002.77433253
GO:0050852T cell receptor signaling pathway9.43e-031.00e+003.7632285
GO:0000922spindle pole9.86e-031.00e+003.7292387
GO:0007097nuclear migration1.04e-021.00e+006.587116
GO:0003334keratinocyte development1.04e-021.00e+006.587116
GO:0002309T cell proliferation involved in immune response1.04e-021.00e+006.587116
GO:0045182translation regulator activity1.04e-021.00e+006.587126
GO:0060789hair follicle placode formation1.04e-021.00e+006.587116
GO:0048554positive regulation of metalloenzyme activity1.04e-021.00e+006.587116
GO:0048029monosaccharide binding1.04e-021.00e+006.587116
GO:0006924activation-induced cell death of T cells1.04e-021.00e+006.587116
GO:0043497regulation of protein heterodimerization activity1.04e-021.00e+006.587116
GO:0050792regulation of viral process1.04e-021.00e+006.587116
GO:0000187activation of MAPK activity1.05e-021.00e+003.6802290
GO:0043065positive regulation of apoptotic process1.08e-021.00e+002.69136268
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.10e-021.00e+003.6492692
GO:0071456cellular response to hypoxia1.10e-021.00e+003.6492392
GO:0006364rRNA processing1.14e-021.00e+003.6182794
GO:0034142toll-like receptor 4 signaling pathway1.19e-021.00e+003.5872496
GO:0008608attachment of spindle microtubules to kinetochore1.21e-021.00e+006.365117
GO:0007091metaphase/anaphase transition of mitotic cell cycle1.21e-021.00e+006.365117
GO:0051988regulation of attachment of spindle microtubules to kinetochore1.21e-021.00e+006.365117
GO:0051156glucose 6-phosphate metabolic process1.21e-021.00e+006.365117
GO:0000028ribosomal small subunit assembly1.21e-021.00e+006.365137
GO:0034101erythrocyte homeostasis1.21e-021.00e+006.365117
GO:0051489regulation of filopodium assembly1.21e-021.00e+006.365117
GO:0030157pancreatic juice secretion1.21e-021.00e+006.365117
GO:0070182DNA polymerase binding1.38e-021.00e+006.172118
GO:0000800lateral element1.38e-021.00e+006.172118
GO:0039702viral budding via host ESCRT complex1.38e-021.00e+006.172118
GO:0000780condensed nuclear chromosome, centromeric region1.38e-021.00e+006.172118
GO:0030496midbody1.49e-021.00e+003.41722108
GO:0002224toll-like receptor signaling pathway1.52e-021.00e+003.40424109
GO:0005815microtubule organizing center1.52e-021.00e+003.40423109
GO:0090136epithelial cell-cell adhesion1.55e-021.00e+006.002119
GO:0047497mitochondrion transport along microtubule1.55e-021.00e+006.002119
GO:0007599hemostasis1.55e-021.00e+006.002119
GO:0097190apoptotic signaling pathway1.62e-021.00e+003.35223113
GO:0019901protein kinase binding1.69e-021.00e+002.44936317
GO:0000209protein polyubiquitination1.71e-021.00e+003.31427116
GO:0031274positive regulation of pseudopodium assembly1.72e-021.00e+005.8501210
GO:0010569regulation of double-strand break repair via homologous recombination1.72e-021.00e+005.8501110
GO:0006268DNA unwinding involved in DNA replication1.72e-021.00e+005.8501110
GO:0005798Golgi-associated vesicle1.72e-021.00e+005.8501110
GO:0060047heart contraction1.72e-021.00e+005.8501110
GO:0007219Notch signaling pathway1.82e-021.00e+003.26523120
GO:0051092positive regulation of NF-kappaB transcription factor activity1.93e-021.00e+003.21823124
GO:0007179transforming growth factor beta receptor signaling pathway2.05e-021.00e+003.17223128
GO:0051443positive regulation of ubiquitin-protein transferase activity2.06e-021.00e+005.5871112
GO:0061136regulation of proteasomal protein catabolic process2.06e-021.00e+005.5871112
GO:1903543positive regulation of exosomal secretion2.06e-021.00e+005.5871112
GO:1901214regulation of neuron death2.06e-021.00e+005.5871112
GO:0031929TOR signaling2.23e-021.00e+005.4721113
GO:0031333negative regulation of protein complex assembly2.40e-021.00e+005.3651114
GO:0031996thioesterase binding2.40e-021.00e+005.3651114
GO:0030131clathrin adaptor complex2.40e-021.00e+005.3651214
GO:0048821erythrocyte development2.57e-021.00e+005.2651115
GO:0030225macrophage differentiation2.57e-021.00e+005.2651115
GO:0031369translation initiation factor binding2.57e-021.00e+005.2651115
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling2.59e-021.00e+002.99223145
GO:0034220ion transmembrane transport2.72e-021.00e+002.95322149
GO:0042176regulation of protein catabolic process2.74e-021.00e+005.1721316
GO:0008284positive regulation of cell proliferation2.75e-021.00e+002.18037382
GO:0042981regulation of apoptotic process2.76e-021.00e+002.94327150
GO:0010008endosome membrane2.79e-021.00e+002.93425151
GO:0010800positive regulation of peptidyl-threonine phosphorylation2.91e-021.00e+005.0851117
GO:0030742GTP-dependent protein binding2.91e-021.00e+005.0851117
GO:0090316positive regulation of intracellular protein transport2.91e-021.00e+005.0851117
GO:0007126meiotic nuclear division2.91e-021.00e+005.0851117
GO:0008543fibroblast growth factor receptor signaling pathway2.96e-021.00e+002.88723156
GO:0007088regulation of mitosis3.08e-021.00e+005.0021118
GO:0046847filopodium assembly3.24e-021.00e+004.9241119
GO:0031572G2 DNA damage checkpoint3.24e-021.00e+004.9241119
GO:0007369gastrulation3.24e-021.00e+004.9241119
GO:0000070mitotic sister chromatid segregation3.24e-021.00e+004.9241119
GO:0045736negative regulation of cyclin-dependent protein serine/threonine kinase activity3.24e-021.00e+004.9241119
GO:0038095Fc-epsilon receptor signaling pathway3.40e-021.00e+002.78023168
GO:0001578microtubule bundle formation3.41e-021.00e+004.8501120
GO:0051881regulation of mitochondrial membrane potential3.41e-021.00e+004.8501120
GO:0043473pigmentation3.41e-021.00e+004.8501120
GO:0043393regulation of protein binding3.41e-021.00e+004.8501220
GO:0005654nucleoplasm3.55e-021.00e+001.4155151082
GO:0031435mitogen-activated protein kinase kinase kinase binding3.58e-021.00e+004.7801121
GO:0045862positive regulation of proteolysis3.58e-021.00e+004.7801121
GO:0031648protein destabilization3.58e-021.00e+004.7801121
GO:0000793condensed chromosome3.58e-021.00e+004.7801121
GO:0032201telomere maintenance via semi-conservative replication3.58e-021.00e+004.7801121
GO:0000281mitotic cytokinesis3.58e-021.00e+004.7801121
GO:0031424keratinization3.75e-021.00e+004.7131122
GO:0051297centrosome organization3.75e-021.00e+004.7131222
GO:0045787positive regulation of cell cycle3.75e-021.00e+004.7131222
GO:0006270DNA replication initiation3.75e-021.00e+004.7131122
GO:1900026positive regulation of substrate adhesion-dependent cell spreading3.91e-021.00e+004.6491123
GO:0007131reciprocal meiotic recombination3.91e-021.00e+004.6491123
GO:0071479cellular response to ionizing radiation3.91e-021.00e+004.6491223
GO:0002040sprouting angiogenesis3.91e-021.00e+004.6491123
GO:0051017actin filament bundle assembly3.91e-021.00e+004.6491123
GO:0006367transcription initiation from RNA polymerase II promoter4.01e-021.00e+002.64923184
GO:0000794condensed nuclear chromosome4.08e-021.00e+004.5871124
GO:0007163establishment or maintenance of cell polarity4.08e-021.00e+004.5871124
GO:0000722telomere maintenance via recombination4.25e-021.00e+004.5281125
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity4.41e-021.00e+004.4721226
GO:0045859regulation of protein kinase activity4.41e-021.00e+004.4721126
GO:0051149positive regulation of muscle cell differentiation4.58e-021.00e+004.4171127
GO:0032467positive regulation of cytokinesis4.58e-021.00e+004.4171127
GO:0031069hair follicle morphogenesis4.58e-021.00e+004.4171127
GO:0007346regulation of mitotic cell cycle4.91e-021.00e+004.3141229
GO:0072686mitotic spindle4.91e-021.00e+004.3141129
GO:0045171intercellular bridge5.08e-021.00e+004.2651130
GO:0031647regulation of protein stability5.08e-021.00e+004.2651130
GO:0006271DNA strand elongation involved in DNA replication5.08e-021.00e+004.2651130
GO:0046677response to antibiotic5.24e-021.00e+004.2181131
GO:0048812neuron projection morphogenesis5.24e-021.00e+004.2181231
GO:0001890placenta development5.24e-021.00e+004.2181131
GO:0007093mitotic cell cycle checkpoint5.24e-021.00e+004.2181131
GO:0007094mitotic spindle assembly checkpoint5.24e-021.00e+004.2181131
GO:0016301kinase activity5.57e-021.00e+004.1281233
GO:0033077T cell differentiation in thymus5.57e-021.00e+004.1281133
GO:0019221cytokine-mediated signaling pathway5.57e-021.00e+002.38422221
GO:0000228nuclear chromosome5.57e-021.00e+004.1281133
GO:0007611learning or memory5.73e-021.00e+004.0851134
GO:0042692muscle cell differentiation5.73e-021.00e+004.0851134
GO:0005876spindle microtubule5.73e-021.00e+004.0851134
GO:0000737DNA catabolic process, endonucleolytic5.90e-021.00e+004.0431135
GO:0034332adherens junction organization6.06e-021.00e+004.0021236
GO:0007077mitotic nuclear envelope disassembly6.06e-021.00e+004.0021136
GO:0045740positive regulation of DNA replication6.06e-021.00e+004.0021136
GO:0006096glycolytic process6.39e-021.00e+003.9241138
GO:0043025neuronal cell body6.68e-021.00e+002.23624245
GO:0006094gluconeogenesis7.20e-021.00e+003.7461143
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process7.36e-021.00e+003.7131144
GO:0021762substantia nigra development7.36e-021.00e+003.7131144
GO:0034613cellular protein localization7.36e-021.00e+003.7131244
GO:0045727positive regulation of translation7.36e-021.00e+003.7131144
GO:0008344adult locomotory behavior7.36e-021.00e+003.7131144
GO:0000122negative regulation of transcription from RNA polymerase II promoter7.42e-021.00e+001.60237570
GO:0044297cell body7.68e-021.00e+003.6491146
GO:0043525positive regulation of neuron apoptotic process7.68e-021.00e+003.6491246
GO:0006959humoral immune response7.84e-021.00e+003.6181147
GO:0048011neurotrophin TRK receptor signaling pathway7.85e-021.00e+002.10124269
GO:0007030Golgi organization8.16e-021.00e+003.5581249
GO:0003684damaged DNA binding8.16e-021.00e+003.5581149
GO:0045087innate immune response8.24e-021.00e+001.53838596
GO:0000775chromosome, centromeric region8.32e-021.00e+003.5281150
GO:0030175filopodium8.32e-021.00e+003.5281250
GO:0000910cytokinesis8.48e-021.00e+003.5001251
GO:0019900kinase binding8.64e-021.00e+003.4721152
GO:0046330positive regulation of JNK cascade9.12e-021.00e+003.3911155
GO:0000724double-strand break repair via homologous recombination9.12e-021.00e+003.3911155
GO:0005793endoplasmic reticulum-Golgi intermediate compartment9.28e-021.00e+003.3651156
GO:0000723telomere maintenance9.28e-021.00e+003.3651156
GO:0033138positive regulation of peptidyl-serine phosphorylation9.75e-021.00e+003.2901159
GO:0007059chromosome segregation1.02e-011.00e+003.2181262
GO:0006302double-strand break repair1.02e-011.00e+003.2181162
GO:0030141secretory granule1.02e-011.00e+003.2181162
GO:0006417regulation of translation1.02e-011.00e+003.2181262
GO:0043154negative regulation of cysteine-type endopeptidase activity involved in apoptotic process1.04e-011.00e+003.1951263
GO:0043231intracellular membrane-bounded organelle1.04e-011.00e+001.85925318
GO:0031295T cell costimulation1.07e-011.00e+003.1501365
GO:0005515protein binding1.08e-011.00e+000.42314626024
GO:0005813centrosome1.09e-011.00e+001.82325326
GO:0035264multicellular organism growth1.10e-011.00e+003.1061167
GO:0003697single-stranded DNA binding1.12e-011.00e+003.0851368
GO:0000777condensed chromosome kinetochore1.12e-011.00e+003.0851168
GO:0018105peptidyl-serine phosphorylation1.13e-011.00e+003.0641469
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.21e-011.00e+002.9631274
GO:0060070canonical Wnt signaling pathway1.22e-011.00e+002.9431175
GO:0010629negative regulation of gene expression1.25e-011.00e+002.9051277
GO:0031902late endosome membrane1.25e-011.00e+002.9051277
GO:0005179hormone activity1.28e-011.00e+002.8681179
GO:0000139Golgi membrane1.29e-011.00e+001.67626361
GO:0045177apical part of cell1.31e-011.00e+002.8321181
GO:0003690double-stranded DNA binding1.39e-011.00e+002.7461286
GO:0042593glucose homeostasis1.40e-011.00e+002.7291187
GO:0016605PML body1.42e-011.00e+002.7131188
GO:0001649osteoblast differentiation1.48e-011.00e+002.6491392
GO:0051726regulation of cell cycle1.55e-011.00e+002.5721197
GO:0055085transmembrane transport1.73e-011.00e+001.40723435
GO:0015630microtubule cytoskeleton1.74e-011.00e+002.39113110
GO:0005819spindle1.77e-011.00e+002.36512112
GO:0051056regulation of small GTPase mediated signal transduction1.82e-011.00e+002.32714115
GO:0043524negative regulation of neuron apoptotic process1.84e-011.00e+002.30212117
GO:0030036actin cytoskeleton organization1.93e-011.00e+002.23012123
GO:0009615response to virus1.97e-011.00e+002.19512126
GO:0042802identical protein binding2.04e-011.00e+001.25323484
GO:0005911cell-cell junction2.11e-011.00e+002.08512136
GO:0005125cytokine activity2.14e-011.00e+002.06411138
GO:0048471perinuclear region of cytoplasm2.16e-011.00e+001.20127502
GO:0008083growth factor activity2.18e-011.00e+002.03311141
GO:0008286insulin receptor signaling pathway2.19e-011.00e+002.02213142
GO:0051260protein homooligomerization2.23e-011.00e+001.99212145
GO:0010628positive regulation of gene expression2.25e-011.00e+001.98214146
GO:0008017microtubule binding2.26e-011.00e+001.97311147
GO:0006974cellular response to DNA damage stimulus2.32e-011.00e+001.93411151
GO:0005634nucleus2.42e-011.00e+000.34010434559
GO:0008022protein C-terminus binding2.45e-011.00e+001.84113161
GO:0006915apoptotic process2.50e-011.00e+001.05629555
GO:0004672protein kinase activity2.66e-011.00e+001.70514177
GO:0019904protein domain specific binding2.68e-011.00e+001.68813179
GO:0001525angiogenesis2.84e-011.00e+001.59513191
GO:0005794Golgi apparatus2.86e-011.00e+000.92029610
GO:0003924GTPase activity2.91e-011.00e+001.55017197
GO:0006184GTP catabolic process3.12e-011.00e+001.43117214
GO:0005759mitochondrial matrix3.29e-011.00e+001.33911228
GO:0030425dendrite3.31e-011.00e+001.32712230
GO:0044281small molecule metabolic process3.51e-011.00e+000.5153151211
GO:0000166nucleotide binding3.65e-011.00e+001.15512259
GO:0007264small GTPase mediated signal transduction3.87e-011.00e+001.04817279
GO:0046872metal ion binding3.98e-011.00e+000.4053101307
GO:0045944positive regulation of transcription from RNA polymerase II promoter4.01e-011.00e+000.54826789
GO:0006200ATP catabolic process4.01e-011.00e+000.98213292
GO:0016567protein ubiquitination4.04e-011.00e+000.96813295
GO:0004674protein serine/threonine kinase activity4.17e-011.00e+000.90515308
GO:0005525GTP binding4.19e-011.00e+000.89617310
GO:0007275multicellular organismal development4.26e-011.00e+000.86811316
GO:0007411axon guidance4.29e-011.00e+000.85513319
GO:0008283cell proliferation4.38e-011.00e+000.81514328
GO:0015031protein transport4.50e-011.00e+000.75918341
GO:0003723RNA binding4.51e-011.00e+000.75418342
GO:0005886plasma membrane4.72e-011.00e+000.1605202582
GO:0005615extracellular space5.01e-011.00e+000.27022957
GO:0005739mitochondrion5.24e-011.00e+000.20928998
GO:0007596blood coagulation5.52e-011.00e+000.34313455
GO:0006468protein phosphorylation5.56e-011.00e+000.32716460
GO:0005783endoplasmic reticulum6.26e-011.00e+000.05313556
GO:0005524ATP binding6.72e-011.00e+00-0.1702151298
GO:0006351transcription, DNA-templated7.30e-011.00e+00-0.326261446
GO:0003677DNA binding8.90e-011.00e+00-1.078131218