reg-snw-8815

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.203	2.78e-07	4.60e-02	3.49e-02

chia-screen-data-Fav-reg-snw-8815 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
PHB2	11331	17	-2.236	2.449	11	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
RNF7	9616	1	-1.366	2.203	46	TF	-	-
[ BANF1 ]	8815	1	-1.048	2.203	10	-	-	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes

Interactions (4)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
BANF1	8815	RNF7	9616	pd	<	reg.ITFP.txt: no annot
GPS1	2873	BANF1	8815	pd	>	reg.ITFP.txt: no annot
GPS1	2873	PHB2	11331	pd	>	reg.ITFP.txt: no annot

Related GO terms (63)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0019788	NEDD8 ligase activity	2.05e-03	1.00e+00	8.931	1	1	4
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	2.05e-03	1.00e+00	8.931	1	1	4
GO:0060744	mammary gland branching involved in thelarche	2.56e-03	1.00e+00	8.610	1	1	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	2.56e-03	1.00e+00	8.610	1	1	5
GO:0015074	DNA integration	2.56e-03	1.00e+00	8.610	1	1	5
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	2.56e-03	1.00e+00	8.610	1	1	5
GO:0050847	progesterone receptor signaling pathway	3.07e-03	1.00e+00	8.347	1	2	6
GO:0007084	mitotic nuclear envelope reassembly	3.07e-03	1.00e+00	8.347	1	1	6
GO:0051775	response to redox state	3.07e-03	1.00e+00	8.347	1	1	6
GO:0031466	Cul5-RING ubiquitin ligase complex	3.07e-03	1.00e+00	8.347	1	1	6
GO:0045116	protein neddylation	3.58e-03	1.00e+00	8.124	1	1	7
GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	3.58e-03	1.00e+00	8.124	1	2	7
GO:0005743	mitochondrial inner membrane	3.89e-03	1.00e+00	4.309	2	9	197
GO:0005634	nucleus	4.05e-03	1.00e+00	1.589	5	158	3246
GO:0010944	negative regulation of transcription by competitive promoter binding	4.09e-03	1.00e+00	7.931	1	1	8
GO:0075713	establishment of integrated proviral latency	4.09e-03	1.00e+00	7.931	1	1	8
GO:0010388	cullin deneddylation	4.09e-03	1.00e+00	7.931	1	4	8
GO:0071354	cellular response to interleukin-6	4.60e-03	1.00e+00	7.762	1	1	9
GO:0005095	GTPase inhibitor activity	5.11e-03	1.00e+00	7.610	1	1	10
GO:0060766	negative regulation of androgen receptor signaling pathway	5.62e-03	1.00e+00	7.472	1	4	11
GO:0060749	mammary gland alveolus development	6.64e-03	1.00e+00	7.231	1	1	13
GO:0016575	histone deacetylation	7.15e-03	1.00e+00	7.124	1	2	14
GO:0000188	inactivation of MAPK activity	7.66e-03	1.00e+00	7.025	1	1	15
GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	7.66e-03	1.00e+00	7.025	1	1	15
GO:0045892	negative regulation of transcription, DNA-templated	9.84e-03	1.00e+00	3.623	2	17	317
GO:0071897	DNA biosynthetic process	1.02e-02	1.00e+00	6.610	1	2	20
GO:0030331	estrogen receptor binding	1.12e-02	1.00e+00	6.472	1	2	22
GO:0008180	COP9 signalosome	1.22e-02	1.00e+00	6.347	1	6	24
GO:0005515	protein binding	1.34e-02	1.00e+00	1.244	5	198	4124
GO:0005507	copper ion binding	1.48e-02	1.00e+00	6.073	1	1	29
GO:0007077	mitotic nuclear envelope disassembly	1.63e-02	1.00e+00	5.931	1	9	32
GO:0007254	JNK cascade	1.73e-02	1.00e+00	5.844	1	1	34
GO:0005737	cytoplasm	2.07e-02	1.00e+00	1.569	4	127	2633
GO:0005694	chromosome	2.79e-02	1.00e+00	5.150	1	4	55
GO:0042826	histone deacetylase binding	2.94e-02	1.00e+00	5.073	1	5	58
GO:0030308	negative regulation of cell growth	3.53e-02	1.00e+00	4.802	1	3	70
GO:0070062	extracellular vesicular exosome	3.63e-02	1.00e+00	1.836	3	51	1641
GO:0016363	nuclear matrix	3.68e-02	1.00e+00	4.742	1	10	73
GO:0001649	osteoblast differentiation	3.73e-02	1.00e+00	4.722	1	5	74
GO:0005739	mitochondrion	3.97e-02	1.00e+00	2.567	2	32	659
GO:0009615	response to virus	4.87e-02	1.00e+00	4.332	1	3	97
GO:0042981	regulation of apoptotic process	5.61e-02	1.00e+00	4.124	1	4	112
GO:0007049	cell cycle	5.75e-02	1.00e+00	4.086	1	8	115
GO:0005654	nucleoplasm	6.69e-02	1.00e+00	2.157	2	68	876
GO:0044212	transcription regulatory region DNA binding	7.11e-02	1.00e+00	3.772	1	13	143
GO:0016567	protein ubiquitination	9.26e-02	1.00e+00	3.377	1	14	188
GO:0043234	protein complex	1.03e-01	1.00e+00	3.217	1	13	210
GO:0019899	enzyme binding	1.03e-01	1.00e+00	3.217	1	7	210
GO:0008285	negative regulation of cell proliferation	1.34e-01	1.00e+00	2.818	1	11	277
GO:0000278	mitotic cell cycle	1.51e-01	1.00e+00	2.637	1	28	314
GO:0043066	negative regulation of apoptotic process	1.54e-01	1.00e+00	2.601	1	8	322
GO:0045893	positive regulation of transcription, DNA-templated	1.79e-01	1.00e+00	2.373	1	21	377
GO:0016032	viral process	2.01e-01	1.00e+00	2.190	1	30	428
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.13e-01	1.00e+00	2.099	1	29	456
GO:0005887	integral component of plasma membrane	2.62e-01	1.00e+00	1.764	1	8	575
GO:0007165	signal transduction	2.79e-01	1.00e+00	1.660	1	24	618
GO:0006355	regulation of transcription, DNA-templated	3.16e-01	1.00e+00	1.450	1	31	715
GO:0008270	zinc ion binding	3.21e-01	1.00e+00	1.426	1	39	727
GO:0003677	DNA binding	4.00e-01	1.00e+00	1.044	1	52	947
GO:0006351	transcription, DNA-templated	4.42e-01	1.00e+00	0.860	1	47	1076
GO:0016020	membrane	4.83e-01	1.00e+00	0.694	1	56	1207
GO:0005730	nucleolus	4.86e-01	1.00e+00	0.682	1	74	1217
GO:0005829	cytosol	6.36e-01	1.00e+00	0.128	1	88	1787

chia-Fav

reg-snw-8815

Statistics

Genes (5)

Interactions (4)

Related GO terms (63)