reg-snw-84231

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.194	3.10e-07	4.86e-02	3.68e-02

chia-screen-data-Fav-reg-snw-84231 subnetwork

Genes (11)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
RNF40	9810	10	-2.082	2.492	38	TF	Yes	-
UBR3	130507	1	-1.620	2.194	18	-	-	-
[ TRAF7 ]	84231	1	-1.285	2.194	23	TF	-	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
KLC3	147700	7	-2.130	2.290	132	TF	Yes	-
LCE1E	353135	7	-2.428	2.414	31	-	Yes	Yes
C16orf13	84326	12	-2.090	2.492	36	-	Yes	-
G6PC3	92579	2	-1.713	2.239	7	-	-	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
SYMPK	8189	11	-1.890	2.492	51	TF	-	-
DRG2	1819	15	-2.526	2.492	11	-	Yes	-

Interactions (11)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
SYMPK	8189	TRAF7	84231	pd	<>	reg.ITFP.txt: no annot
DRG2	1819	SYMPK	8189	pd	<	reg.ITFP.txt: no annot
SYMPK	8189	C16orf13	84326	pd	>	reg.ITFP.txt: no annot
TRAF7	84231	G6PC3	92579	pd	>	reg.ITFP.txt: no annot
RNF40	9810	KLC3	147700	pd	<>	reg.ITFP.txt: no annot
KLC3	147700	LCE1E	353135	pd	>	reg.ITFP.txt: no annot
GPS1	2873	C16orf13	84326	pd	>	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
RNF40	9810	TRAF7	84231	pd	<>	reg.ITFP.txt: no annot
SYMPK	8189	RNF40	9810	pd	<>	reg.ITFP.txt: no annot
TRAF7	84231	UBR3	130507	pd	>	reg.ITFP.txt: no annot

Related GO terms (89)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0016874	ligase activity	4.95e-04	1.00e+00	4.189	3	11	146
GO:0004842	ubiquitin-protein transferase activity	8.97e-04	1.00e+00	3.895	3	17	179
GO:0000151	ubiquitin ligase complex	1.27e-03	1.00e+00	5.209	2	4	48
GO:0004346	glucose-6-phosphatase activity	3.38e-03	1.00e+00	8.209	1	1	3
GO:0042048	olfactory behavior	3.38e-03	1.00e+00	8.209	1	1	3
GO:0015760	glucose-6-phosphate transport	3.38e-03	1.00e+00	8.209	1	1	3
GO:0033503	HULC complex	4.50e-03	1.00e+00	7.794	1	1	4
GO:0006511	ubiquitin-dependent protein catabolic process	4.57e-03	1.00e+00	4.270	2	6	92
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	5.62e-03	1.00e+00	7.472	1	1	5
GO:0000185	activation of MAPKKK activity	6.74e-03	1.00e+00	7.209	1	1	6
GO:0050847	progesterone receptor signaling pathway	6.74e-03	1.00e+00	7.209	1	2	6
GO:0051156	glucose 6-phosphate metabolic process	6.74e-03	1.00e+00	7.209	1	1	6
GO:0043005	neuron projection	6.82e-03	1.00e+00	3.974	2	6	113
GO:0033523	histone H2B ubiquitination	7.86e-03	1.00e+00	6.987	1	1	7
GO:0010944	negative regulation of transcription by competitive promoter binding	8.98e-03	1.00e+00	6.794	1	1	8
GO:0008088	axon cargo transport	8.98e-03	1.00e+00	6.794	1	1	8
GO:0010388	cullin deneddylation	8.98e-03	1.00e+00	6.794	1	4	8
GO:0010390	histone monoubiquitination	8.98e-03	1.00e+00	6.794	1	2	8
GO:0071354	cellular response to interleukin-6	1.01e-02	1.00e+00	6.624	1	1	9
GO:0035253	ciliary rootlet	1.01e-02	1.00e+00	6.624	1	1	9
GO:0001967	suckling behavior	1.12e-02	1.00e+00	6.472	1	4	10
GO:0005095	GTPase inhibitor activity	1.12e-02	1.00e+00	6.472	1	1	10
GO:0035307	positive regulation of protein dephosphorylation	1.12e-02	1.00e+00	6.472	1	1	10
GO:0060766	negative regulation of androgen receptor signaling pathway	1.23e-02	1.00e+00	6.335	1	4	11
GO:0017075	syntaxin-1 binding	1.46e-02	1.00e+00	6.094	1	1	13
GO:0016575	histone deacetylation	1.57e-02	1.00e+00	5.987	1	2	14
GO:0031514	motile cilium	1.57e-02	1.00e+00	5.987	1	1	14
GO:0000188	inactivation of MAPK activity	1.68e-02	1.00e+00	5.887	1	1	15
GO:0016567	protein ubiquitination	1.81e-02	1.00e+00	3.239	2	14	188
GO:0006378	mRNA polyadenylation	2.01e-02	1.00e+00	5.624	1	3	18
GO:2001235	positive regulation of apoptotic signaling pathway	2.12e-02	1.00e+00	5.546	1	2	19
GO:0071897	DNA biosynthetic process	2.23e-02	1.00e+00	5.472	1	2	20
GO:0019894	kinesin binding	2.34e-02	1.00e+00	5.402	1	1	21
GO:0031424	keratinization	2.56e-02	1.00e+00	5.270	1	2	23
GO:0008180	COP9 signalosome	2.67e-02	1.00e+00	5.209	1	6	24
GO:0009790	embryo development	3.00e-02	1.00e+00	5.039	1	1	27
GO:0007608	sensory perception of smell	3.00e-02	1.00e+00	5.039	1	2	27
GO:0006094	gluconeogenesis	3.44e-02	1.00e+00	4.840	1	1	31
GO:0005871	kinesin complex	3.44e-02	1.00e+00	4.840	1	3	31
GO:0016020	membrane	3.75e-02	1.00e+00	1.557	4	56	1207
GO:0007254	JNK cascade	3.77e-02	1.00e+00	4.707	1	1	34
GO:0008645	hexose transport	3.98e-02	1.00e+00	4.624	1	8	36
GO:0003777	microtubule motor activity	4.31e-02	1.00e+00	4.509	1	3	39
GO:0008270	zinc ion binding	4.32e-02	1.00e+00	1.873	3	39	727
GO:0015758	glucose transport	5.28e-02	1.00e+00	4.209	1	8	48
GO:0043410	positive regulation of MAPK cascade	5.49e-02	1.00e+00	4.150	1	1	50
GO:0016311	dephosphorylation	6.03e-02	1.00e+00	4.013	1	3	55
GO:0042826	histone deacetylase binding	6.35e-02	1.00e+00	3.936	1	5	58
GO:0016023	cytoplasmic membrane-bounded vesicle	6.88e-02	1.00e+00	3.817	1	1	63
GO:0005923	tight junction	6.98e-02	1.00e+00	3.794	1	2	64
GO:0030308	negative regulation of cell growth	7.61e-02	1.00e+00	3.665	1	3	70
GO:0001649	osteoblast differentiation	8.03e-02	1.00e+00	3.585	1	5	74
GO:0008017	microtubule binding	1.04e-01	1.00e+00	3.194	1	9	97
GO:0042981	regulation of apoptotic process	1.19e-01	1.00e+00	2.987	1	4	112
GO:0007049	cell cycle	1.22e-01	1.00e+00	2.948	1	8	115
GO:0032403	protein complex binding	1.37e-01	1.00e+00	2.772	1	5	130
GO:0031625	ubiquitin protein ligase binding	1.45e-01	1.00e+00	2.685	1	7	138
GO:0005737	cytoplasm	1.48e-01	1.00e+00	0.753	5	127	2633
GO:0044212	transcription regulatory region DNA binding	1.50e-01	1.00e+00	2.634	1	13	143
GO:0007165	signal transduction	1.51e-01	1.00e+00	1.523	2	24	618
GO:0001701	in utero embryonic development	1.61e-01	1.00e+00	2.527	1	7	154
GO:0005739	mitochondrion	1.67e-01	1.00e+00	1.430	2	32	659
GO:0005874	microtubule	1.69e-01	1.00e+00	2.445	1	10	163
GO:0008152	metabolic process	1.87e-01	1.00e+00	2.286	1	6	182
GO:0006355	regulation of transcription, DNA-templated	1.90e-01	1.00e+00	1.312	2	31	715
GO:0005975	carbohydrate metabolic process	1.91e-01	1.00e+00	2.255	1	10	186
GO:0005856	cytoskeleton	1.94e-01	1.00e+00	2.224	1	8	190
GO:0005743	mitochondrial inner membrane	2.01e-01	1.00e+00	2.172	1	9	197
GO:0005525	GTP binding	2.01e-01	1.00e+00	2.172	1	12	197
GO:0019899	enzyme binding	2.13e-01	1.00e+00	2.080	1	7	210
GO:0007155	cell adhesion	2.43e-01	1.00e+00	1.863	1	8	244
GO:0005654	nucleoplasm	2.59e-01	1.00e+00	1.019	2	68	876
GO:0008285	negative regulation of cell proliferation	2.71e-01	1.00e+00	1.680	1	11	277
GO:0045892	negative regulation of transcription, DNA-templated	3.05e-01	1.00e+00	1.486	1	17	317
GO:0055085	transmembrane transport	3.14e-01	1.00e+00	1.432	1	13	329
GO:0045893	positive regulation of transcription, DNA-templated	3.52e-01	1.00e+00	1.236	1	21	377
GO:0005789	endoplasmic reticulum membrane	3.59e-01	1.00e+00	1.198	1	7	387
GO:0006915	apoptotic process	3.77e-01	1.00e+00	1.111	1	15	411
GO:0042803	protein homodimerization activity	3.89e-01	1.00e+00	1.053	1	13	428
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	4.09e-01	1.00e+00	0.961	1	29	456
GO:0005887	integral component of plasma membrane	4.87e-01	1.00e+00	0.627	1	8	575
GO:0005634	nucleus	5.25e-01	1.00e+00	0.130	4	158	3246
GO:0005515	protein binding	5.29e-01	1.00e+00	0.106	5	198	4124
GO:0016021	integral component of membrane	5.32e-01	1.00e+00	0.218	2	19	1526
GO:0044281	small molecule metabolic process	6.30e-01	1.00e+00	0.073	1	35	844
GO:0006351	transcription, DNA-templated	7.23e-01	1.00e+00	-0.277	1	47	1076
GO:0005730	nucleolus	7.69e-01	1.00e+00	-0.455	1	74	1217
GO:0070062	extracellular vesicular exosome	8.68e-01	1.00e+00	-0.886	1	51	1641
GO:0005886	plasma membrane	8.91e-01	1.00e+00	-1.007	1	46	1784

chia-Fav

reg-snw-84231

Statistics

Genes (11)

Interactions (11)

Related GO terms (89)