reg-snw-8189

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.492	7.20e-09	5.76e-03	5.35e-03

chia-screen-data-Fav-reg-snw-8189 subnetwork

Genes (6)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
RNF40	9810	10	-2.082	2.492	38	TF	Yes	-
C16orf13	84326	12	-2.090	2.492	36	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
[ SYMPK ]	8189	11	-1.890	2.492	51	TF	-	-
DRG2	1819	15	-2.526	2.492	11	-	Yes	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes

Interactions (5)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
DRG2	1819	SYMPK	8189	pd	<	reg.ITFP.txt: no annot
SYMPK	8189	C16orf13	84326	pd	>	reg.ITFP.txt: no annot
GPS1	2873	C16orf13	84326	pd	>	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
SYMPK	8189	RNF40	9810	pd	<>	reg.ITFP.txt: no annot

Related GO terms (55)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0033503	HULC complex	2.46e-03	1.00e+00	8.668	1	1	4
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	3.07e-03	1.00e+00	8.347	1	1	5
GO:0050847	progesterone receptor signaling pathway	3.68e-03	1.00e+00	8.083	1	2	6
GO:0033523	histone H2B ubiquitination	4.29e-03	1.00e+00	7.861	1	1	7
GO:0010944	negative regulation of transcription by competitive promoter binding	4.91e-03	1.00e+00	7.668	1	1	8
GO:0010390	histone monoubiquitination	4.91e-03	1.00e+00	7.668	1	2	8
GO:0010388	cullin deneddylation	4.91e-03	1.00e+00	7.668	1	4	8
GO:0071354	cellular response to interleukin-6	5.52e-03	1.00e+00	7.499	1	1	9
GO:0005095	GTPase inhibitor activity	6.13e-03	1.00e+00	7.347	1	1	10
GO:0035307	positive regulation of protein dephosphorylation	6.13e-03	1.00e+00	7.347	1	1	10
GO:0060766	negative regulation of androgen receptor signaling pathway	6.74e-03	1.00e+00	7.209	1	4	11
GO:0017075	syntaxin-1 binding	7.96e-03	1.00e+00	6.968	1	1	13
GO:0016575	histone deacetylation	8.57e-03	1.00e+00	6.861	1	2	14
GO:0000188	inactivation of MAPK activity	9.18e-03	1.00e+00	6.762	1	1	15
GO:0006378	mRNA polyadenylation	1.10e-02	1.00e+00	6.499	1	3	18
GO:0071897	DNA biosynthetic process	1.22e-02	1.00e+00	6.347	1	2	20
GO:0008180	COP9 signalosome	1.47e-02	1.00e+00	6.083	1	6	24
GO:0007254	JNK cascade	2.07e-02	1.00e+00	5.581	1	1	34
GO:0016020	membrane	2.82e-02	1.00e+00	2.016	3	56	1207
GO:0000151	ubiquitin ligase complex	2.91e-02	1.00e+00	5.083	1	4	48
GO:0042826	histone deacetylase binding	3.51e-02	1.00e+00	4.810	1	5	58
GO:0005923	tight junction	3.87e-02	1.00e+00	4.668	1	2	64
GO:0030308	negative regulation of cell growth	4.23e-02	1.00e+00	4.539	1	3	70
GO:0001649	osteoblast differentiation	4.46e-02	1.00e+00	4.459	1	5	74
GO:0005737	cytoplasm	4.89e-02	1.00e+00	1.306	4	127	2633
GO:0007165	signal transduction	5.06e-02	1.00e+00	2.397	2	24	618
GO:0006511	ubiquitin-dependent protein catabolic process	5.52e-02	1.00e+00	4.145	1	6	92
GO:0005739	mitochondrion	5.69e-02	1.00e+00	2.304	2	32	659
GO:0042981	regulation of apoptotic process	6.69e-02	1.00e+00	3.861	1	4	112
GO:0043005	neuron projection	6.75e-02	1.00e+00	3.848	1	6	113
GO:0007049	cell cycle	6.86e-02	1.00e+00	3.823	1	8	115
GO:0032403	protein complex binding	7.73e-02	1.00e+00	3.646	1	5	130
GO:0031625	ubiquitin protein ligase binding	8.19e-02	1.00e+00	3.560	1	7	138
GO:0044212	transcription regulatory region DNA binding	8.47e-02	1.00e+00	3.509	1	13	143
GO:0016874	ligase activity	8.64e-02	1.00e+00	3.479	1	11	146
GO:0005654	nucleoplasm	9.46e-02	1.00e+00	1.894	2	68	876
GO:0005634	nucleus	9.92e-02	1.00e+00	1.004	4	158	3246
GO:0004842	ubiquitin-protein transferase activity	1.05e-01	1.00e+00	3.185	1	17	179
GO:0005856	cytoskeleton	1.11e-01	1.00e+00	3.099	1	8	190
GO:0005743	mitochondrial inner membrane	1.15e-01	1.00e+00	3.046	1	9	197
GO:0005525	GTP binding	1.15e-01	1.00e+00	3.046	1	12	197
GO:0019899	enzyme binding	1.22e-01	1.00e+00	2.954	1	7	210
GO:0007155	cell adhesion	1.41e-01	1.00e+00	2.738	1	8	244
GO:0008285	negative regulation of cell proliferation	1.59e-01	1.00e+00	2.555	1	11	277
GO:0045892	negative regulation of transcription, DNA-templated	1.80e-01	1.00e+00	2.360	1	17	317
GO:0045893	positive regulation of transcription, DNA-templated	2.10e-01	1.00e+00	2.110	1	21	377
GO:0005515	protein binding	2.11e-01	1.00e+00	0.659	4	198	4124
GO:0042803	protein homodimerization activity	2.36e-01	1.00e+00	1.927	1	13	428
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.49e-01	1.00e+00	1.836	1	29	456
GO:0005887	integral component of plasma membrane	3.05e-01	1.00e+00	1.501	1	8	575
GO:0006355	regulation of transcription, DNA-templated	3.66e-01	1.00e+00	1.187	1	31	715
GO:0008270	zinc ion binding	3.71e-01	1.00e+00	1.163	1	39	727
GO:0005730	nucleolus	5.50e-01	1.00e+00	0.419	1	74	1217
GO:0070062	extracellular vesicular exosome	6.69e-01	1.00e+00	-0.012	1	51	1641
GO:0005886	plasma membrane	7.02e-01	1.00e+00	-0.132	1	46	1784

chia-Fav

reg-snw-8189

Statistics

Genes (6)

Interactions (5)

Related GO terms (55)