reg-snw-64978

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.247	1.65e-07	3.49e-02	2.69e-02

chia-screen-data-Fav-reg-snw-64978 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
CLPP	8192	4	-2.200	2.291	10	-	Yes	-
[ MRPL38 ]	64978	1	-0.435	2.247	2	-	-	-
PHB2	11331	17	-2.236	2.449	11	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes

Interactions (4)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
GPS1	2873	CLPP	8192	pd	>	reg.ITFP.txt: no annot
GPS1	2873	MRPL38	64978	pd	>	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
GPS1	2873	PHB2	11331	pd	>	reg.ITFP.txt: no annot

Related GO terms (51)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005739	mitochondrion	9.73e-05	9.50e-01	3.567	4	32	659
GO:0009368	endopeptidase Clp complex	1.02e-03	1.00e+00	9.931	1	1	2
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	2.05e-03	1.00e+00	8.931	1	1	4
GO:0060744	mammary gland branching involved in thelarche	2.56e-03	1.00e+00	8.610	1	1	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	2.56e-03	1.00e+00	8.610	1	1	5
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	2.56e-03	1.00e+00	8.610	1	1	5
GO:0050847	progesterone receptor signaling pathway	3.07e-03	1.00e+00	8.347	1	2	6
GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	3.58e-03	1.00e+00	8.124	1	2	7
GO:0005743	mitochondrial inner membrane	3.89e-03	1.00e+00	4.309	2	9	197
GO:0010944	negative regulation of transcription by competitive promoter binding	4.09e-03	1.00e+00	7.931	1	1	8
GO:0010388	cullin deneddylation	4.09e-03	1.00e+00	7.931	1	4	8
GO:0071354	cellular response to interleukin-6	4.60e-03	1.00e+00	7.762	1	1	9
GO:0005095	GTPase inhibitor activity	5.11e-03	1.00e+00	7.610	1	1	10
GO:0060766	negative regulation of androgen receptor signaling pathway	5.62e-03	1.00e+00	7.472	1	4	11
GO:0051603	proteolysis involved in cellular protein catabolic process	6.13e-03	1.00e+00	7.347	1	1	12
GO:0060749	mammary gland alveolus development	6.64e-03	1.00e+00	7.231	1	1	13
GO:0016575	histone deacetylation	7.15e-03	1.00e+00	7.124	1	2	14
GO:0000188	inactivation of MAPK activity	7.66e-03	1.00e+00	7.025	1	1	15
GO:0045892	negative regulation of transcription, DNA-templated	9.84e-03	1.00e+00	3.623	2	17	317
GO:0071897	DNA biosynthetic process	1.02e-02	1.00e+00	6.610	1	2	20
GO:0030331	estrogen receptor binding	1.12e-02	1.00e+00	6.472	1	2	22
GO:0008180	COP9 signalosome	1.22e-02	1.00e+00	6.347	1	6	24
GO:0008233	peptidase activity	1.43e-02	1.00e+00	6.124	1	2	28
GO:0007254	JNK cascade	1.73e-02	1.00e+00	5.844	1	1	34
GO:0005840	ribosome	2.03e-02	1.00e+00	5.610	1	2	40
GO:0042826	histone deacetylase binding	2.94e-02	1.00e+00	5.073	1	5	58
GO:0030308	negative regulation of cell growth	3.53e-02	1.00e+00	4.802	1	3	70
GO:0016363	nuclear matrix	3.68e-02	1.00e+00	4.742	1	10	73
GO:0001649	osteoblast differentiation	3.73e-02	1.00e+00	4.722	1	5	74
GO:0004252	serine-type endopeptidase activity	3.93e-02	1.00e+00	4.646	1	1	78
GO:0051260	protein homooligomerization	4.38e-02	1.00e+00	4.489	1	2	87
GO:0042981	regulation of apoptotic process	5.61e-02	1.00e+00	4.124	1	4	112
GO:0007049	cell cycle	5.75e-02	1.00e+00	4.086	1	8	115
GO:0005759	mitochondrial matrix	6.92e-02	1.00e+00	3.813	1	7	139
GO:0044212	transcription regulatory region DNA binding	7.11e-02	1.00e+00	3.772	1	13	143
GO:0043234	protein complex	1.03e-01	1.00e+00	3.217	1	13	210
GO:0019899	enzyme binding	1.03e-01	1.00e+00	3.217	1	7	210
GO:0005515	protein binding	1.05e-01	1.00e+00	0.922	4	198	4124
GO:0008285	negative regulation of cell proliferation	1.34e-01	1.00e+00	2.818	1	11	277
GO:0042802	identical protein binding	1.69e-01	1.00e+00	2.464	1	15	354
GO:0045893	positive regulation of transcription, DNA-templated	1.79e-01	1.00e+00	2.373	1	21	377
GO:0070062	extracellular vesicular exosome	1.99e-01	1.00e+00	1.251	2	51	1641
GO:0005634	nucleus	2.08e-01	1.00e+00	0.852	3	158	3246
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.13e-01	1.00e+00	2.099	1	29	456
GO:0005887	integral component of plasma membrane	2.62e-01	1.00e+00	1.764	1	8	575
GO:0007165	signal transduction	2.79e-01	1.00e+00	1.660	1	24	618
GO:0006355	regulation of transcription, DNA-templated	3.16e-01	1.00e+00	1.450	1	31	715
GO:0005654	nucleoplasm	3.75e-01	1.00e+00	1.157	1	68	876
GO:0005737	cytoplasm	4.09e-01	1.00e+00	0.569	2	127	2633
GO:0006351	transcription, DNA-templated	4.42e-01	1.00e+00	0.860	1	47	1076
GO:0016020	membrane	4.83e-01	1.00e+00	0.694	1	56	1207

chia-Fav

reg-snw-64978

Statistics

Genes (5)

Interactions (4)

Related GO terms (51)