reg-snw-649

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.373	3.44e-08	1.46e-02	1.22e-02

chia-screen-data-Fav-reg-snw-649 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
PDLIM7	9260	2	-1.779	2.373	19	TF	-	-
C16orf13	84326	12	-2.090	2.492	36	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
[ BMP1 ]	649	1	-1.634	2.373	5	-	-	-

Interactions (4)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PDLIM7	9260	C16orf13	84326	pd	>	reg.ITFP.txt: no annot
GPS1	2873	C16orf13	84326	pd	>	reg.ITFP.txt: no annot
BMP1	649	PDLIM7	9260	pd	<	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot

Related GO terms (64)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0001503	ossification	3.19e-04	1.00e+00	6.124	2	2	56
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	2.56e-03	1.00e+00	8.610	1	1	5
GO:0031988	membrane-bounded vesicle	3.07e-03	1.00e+00	8.347	1	1	6
GO:0050847	progesterone receptor signaling pathway	3.07e-03	1.00e+00	8.347	1	2	6
GO:0061036	positive regulation of cartilage development	3.58e-03	1.00e+00	8.124	1	2	7
GO:0010944	negative regulation of transcription by competitive promoter binding	4.09e-03	1.00e+00	7.931	1	1	8
GO:0010388	cullin deneddylation	4.09e-03	1.00e+00	7.931	1	4	8
GO:0030154	cell differentiation	4.17e-03	1.00e+00	4.259	2	5	204
GO:0007275	multicellular organismal development	4.58e-03	1.00e+00	4.190	2	9	214
GO:0071354	cellular response to interleukin-6	4.60e-03	1.00e+00	7.762	1	1	9
GO:0005095	GTPase inhibitor activity	5.11e-03	1.00e+00	7.610	1	1	10
GO:0060766	negative regulation of androgen receptor signaling pathway	5.62e-03	1.00e+00	7.472	1	4	11
GO:0001502	cartilage condensation	6.64e-03	1.00e+00	7.231	1	2	13
GO:0016575	histone deacetylation	7.15e-03	1.00e+00	7.124	1	2	14
GO:0000188	inactivation of MAPK activity	7.66e-03	1.00e+00	7.025	1	1	15
GO:0071897	DNA biosynthetic process	1.02e-02	1.00e+00	6.610	1	2	20
GO:0008180	COP9 signalosome	1.22e-02	1.00e+00	6.347	1	6	24
GO:0008233	peptidase activity	1.43e-02	1.00e+00	6.124	1	2	28
GO:0042157	lipoprotein metabolic process	1.63e-02	1.00e+00	5.931	1	4	32
GO:0007254	JNK cascade	1.73e-02	1.00e+00	5.844	1	1	34
GO:0008237	metallopeptidase activity	1.93e-02	1.00e+00	5.684	1	3	38
GO:0045669	positive regulation of osteoblast differentiation	2.08e-02	1.00e+00	5.574	1	2	41
GO:0001725	stress fiber	2.33e-02	1.00e+00	5.408	1	6	46
GO:0006898	receptor-mediated endocytosis	2.63e-02	1.00e+00	5.231	1	1	52
GO:0001726	ruffle	2.69e-02	1.00e+00	5.204	1	2	53
GO:0042826	histone deacetylase binding	2.94e-02	1.00e+00	5.073	1	5	58
GO:0004222	metalloendopeptidase activity	3.23e-02	1.00e+00	4.931	1	1	64
GO:0030308	negative regulation of cell growth	3.53e-02	1.00e+00	4.802	1	3	70
GO:0001649	osteoblast differentiation	3.73e-02	1.00e+00	4.722	1	5	74
GO:0001501	skeletal system development	4.13e-02	1.00e+00	4.574	1	2	82
GO:0022617	extracellular matrix disassembly	4.28e-02	1.00e+00	4.522	1	2	85
GO:0008083	growth factor activity	4.38e-02	1.00e+00	4.489	1	1	87
GO:0005125	cytokine activity	4.48e-02	1.00e+00	4.456	1	1	89
GO:0030036	actin cytoskeleton organization	4.53e-02	1.00e+00	4.440	1	4	90
GO:0008270	zinc ion binding	4.76e-02	1.00e+00	2.426	2	39	727
GO:0042981	regulation of apoptotic process	5.61e-02	1.00e+00	4.124	1	4	112
GO:0005578	proteinaceous extracellular matrix	5.75e-02	1.00e+00	4.086	1	4	115
GO:0007049	cell cycle	5.75e-02	1.00e+00	4.086	1	8	115
GO:0015629	actin cytoskeleton	6.77e-02	1.00e+00	3.844	1	5	136
GO:0044212	transcription regulatory region DNA binding	7.11e-02	1.00e+00	3.772	1	13	143
GO:0005743	mitochondrial inner membrane	9.69e-02	1.00e+00	3.309	1	9	197
GO:0019899	enzyme binding	1.03e-01	1.00e+00	3.217	1	7	210
GO:0030198	extracellular matrix organization	1.08e-01	1.00e+00	3.144	1	7	221
GO:0005737	cytoplasm	1.25e-01	1.00e+00	1.154	3	127	2633
GO:0006508	proteolysis	1.28e-01	1.00e+00	2.887	1	11	264
GO:0008285	negative regulation of cell proliferation	1.34e-01	1.00e+00	2.818	1	11	277
GO:0005925	focal adhesion	1.36e-01	1.00e+00	2.792	1	14	282
GO:0045892	negative regulation of transcription, DNA-templated	1.52e-01	1.00e+00	2.623	1	17	317
GO:0005509	calcium ion binding	1.67e-01	1.00e+00	2.476	1	9	351
GO:0045893	positive regulation of transcription, DNA-templated	1.79e-01	1.00e+00	2.373	1	21	377
GO:0005794	Golgi apparatus	1.95e-01	1.00e+00	2.235	1	6	415
GO:0005634	nucleus	2.08e-01	1.00e+00	0.852	3	158	3246
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.13e-01	1.00e+00	2.099	1	29	456
GO:0005887	integral component of plasma membrane	2.62e-01	1.00e+00	1.764	1	8	575
GO:0007165	signal transduction	2.79e-01	1.00e+00	1.660	1	24	618
GO:0005615	extracellular space	2.92e-01	1.00e+00	1.585	1	15	651
GO:0005739	mitochondrion	2.95e-01	1.00e+00	1.567	1	32	659
GO:0005576	extracellular region	2.96e-01	1.00e+00	1.559	1	15	663
GO:0006355	regulation of transcription, DNA-templated	3.16e-01	1.00e+00	1.450	1	31	715
GO:0005515	protein binding	3.57e-01	1.00e+00	0.507	3	198	4124
GO:0044281	small molecule metabolic process	3.64e-01	1.00e+00	1.210	1	35	844
GO:0005654	nucleoplasm	3.75e-01	1.00e+00	1.157	1	68	876
GO:0016020	membrane	4.83e-01	1.00e+00	0.694	1	56	1207
GO:0070062	extracellular vesicular exosome	6.02e-01	1.00e+00	0.251	1	51	1641

chia-Fav

reg-snw-649

Statistics

Genes (5)

Interactions (4)

Related GO terms (64)