reg-snw-5347

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.228	2.06e-07	3.94e-02	3.01e-02

chia-screen-data-Fav-reg-snw-5347 subnetwork

Genes (7)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
NDUFA4L2	56901	44	-2.477	2.459	21	-	Yes	-
[ PLK1 ]	5347	1	-1.592	2.228	53	-	-	-
APLP2	334	15	-2.732	2.389	4	-	Yes	Yes
FBXL6	26233	28	-2.253	2.689	22	-	Yes	-
CENPA	1058	27	-2.185	2.393	205	TF	Yes	-
SUV39H2	79723	27	-2.307	2.410	21	-	Yes	Yes
SFPQ	6421	15	-2.051	2.389	142	TF	Yes	-

Interactions (6)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CENPA	1058	FBXL6	26233	pd	>	reg.ITFP.txt: no annot
CENPA	1058	PLK1	5347	pd	>	reg.ITFP.txt: no annot
APLP2	334	SFPQ	6421	pd	<	reg.ITFP.txt: no annot
CENPA	1058	SUV39H2	79723	pd	>	reg.ITFP.txt: no annot
PLK1	5347	SFPQ	6421	pd	<	reg.ITFP.txt: no annot
CENPA	1058	NDUFA4L2	56901	pd	>	reg.ITFP.txt: no annot

Related GO terms (125)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0042754	negative regulation of circadian rhythm	6.60e-06	6.44e-02	8.861	2	2	6
GO:0043393	regulation of protein binding	3.99e-05	3.90e-01	7.639	2	2	14
GO:0000976	transcription regulatory region sequence-specific DNA binding	1.31e-04	1.00e+00	6.802	2	3	25
GO:0048511	rhythmic process	3.06e-04	1.00e+00	6.198	2	5	38
GO:0000775	chromosome, centromeric region	3.56e-04	1.00e+00	6.088	2	6	41
GO:0000939	condensed chromosome inner kinetochore	7.17e-04	1.00e+00	10.446	1	1	1
GO:0000785	chromatin	7.39e-04	1.00e+00	5.563	2	6	59
GO:0007092	activation of mitotic anaphase-promoting complex activity	1.43e-03	1.00e+00	9.446	1	1	2
GO:0036123	histone H3-K9 dimethylation	2.15e-03	1.00e+00	8.861	1	1	3
GO:0010997	anaphase-promoting complex binding	2.15e-03	1.00e+00	8.861	1	1	3
GO:0000778	condensed nuclear chromosome kinetochore	2.15e-03	1.00e+00	8.861	1	2	3
GO:0071459	protein localization to chromosome, centromeric region	2.15e-03	1.00e+00	8.861	1	1	3
GO:1902177	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	2.15e-03	1.00e+00	8.861	1	1	3
GO:0000942	condensed nuclear chromosome outer kinetochore	2.15e-03	1.00e+00	8.861	1	2	3
GO:0046914	transition metal ion binding	2.15e-03	1.00e+00	8.861	1	1	3
GO:0030071	regulation of mitotic metaphase/anaphase transition	2.86e-03	1.00e+00	8.446	1	2	4
GO:0006333	chromatin assembly or disassembly	2.86e-03	1.00e+00	8.446	1	1	4
GO:0036124	histone H3-K9 trimethylation	2.86e-03	1.00e+00	8.446	1	2	4
GO:0040038	polar body extrusion after meiotic divisions	2.86e-03	1.00e+00	8.446	1	1	4
GO:0007176	regulation of epidermal growth factor-activated receptor activity	2.86e-03	1.00e+00	8.446	1	1	4
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.08e-03	1.00e+00	3.198	3	29	456
GO:0007091	metaphase/anaphase transition of mitotic cell cycle	3.58e-03	1.00e+00	8.124	1	2	5
GO:0042382	paraspeckles	3.58e-03	1.00e+00	8.124	1	3	5
GO:0071168	protein localization to chromatin	3.58e-03	1.00e+00	8.124	1	2	5
GO:0046974	histone methyltransferase activity (H3-K9 specific)	4.29e-03	1.00e+00	7.861	1	1	6
GO:0007140	male meiosis	5.01e-03	1.00e+00	7.639	1	1	7
GO:0000780	condensed nuclear chromosome, centromeric region	5.01e-03	1.00e+00	7.639	1	1	7
GO:0007617	mating behavior	5.01e-03	1.00e+00	7.639	1	1	7
GO:0051382	kinetochore assembly	5.01e-03	1.00e+00	7.639	1	2	7
GO:0000380	alternative mRNA splicing, via spliceosome	5.01e-03	1.00e+00	7.639	1	2	7
GO:0051233	spindle midzone	5.72e-03	1.00e+00	7.446	1	1	8
GO:0006878	cellular copper ion homeostasis	5.72e-03	1.00e+00	7.446	1	1	8
GO:0001967	suckling behavior	7.15e-03	1.00e+00	7.124	1	4	10
GO:0001578	microtubule bundle formation	7.15e-03	1.00e+00	7.124	1	2	10
GO:0016567	protein ubiquitination	7.27e-03	1.00e+00	3.891	2	14	188
GO:0000132	establishment of mitotic spindle orientation	8.57e-03	1.00e+00	6.861	1	2	12
GO:0051297	centrosome organization	8.57e-03	1.00e+00	6.861	1	1	12
GO:0051443	positive regulation of ubiquitin-protein transferase activity	1.00e-02	1.00e+00	6.639	1	2	14
GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	1.00e-02	1.00e+00	6.639	1	3	14
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	1.00e-02	1.00e+00	6.639	1	1	14
GO:0000281	mitotic cytokinesis	1.07e-02	1.00e+00	6.539	1	3	15
GO:0031572	G2 DNA damage checkpoint	1.07e-02	1.00e+00	6.539	1	2	15
GO:0045184	establishment of protein localization	1.07e-02	1.00e+00	6.539	1	1	15
GO:0070932	histone H3 deacetylation	1.07e-02	1.00e+00	6.539	1	2	15
GO:0031648	protein destabilization	1.14e-02	1.00e+00	6.446	1	2	16
GO:0045862	positive regulation of proteolysis	1.21e-02	1.00e+00	6.359	1	3	17
GO:0000070	mitotic sister chromatid segregation	1.21e-02	1.00e+00	6.359	1	2	17
GO:0003682	chromatin binding	1.28e-02	1.00e+00	3.469	2	15	252
GO:0005720	nuclear heterochromatin	1.43e-02	1.00e+00	6.124	1	3	20
GO:0034080	CENP-A containing nucleosome assembly	1.43e-02	1.00e+00	6.124	1	2	20
GO:0007346	regulation of mitotic cell cycle	1.50e-02	1.00e+00	6.054	1	2	21
GO:0046677	response to antibiotic	1.71e-02	1.00e+00	5.861	1	1	24
GO:0005876	spindle microtubule	1.71e-02	1.00e+00	5.861	1	4	24
GO:0030901	midbrain development	1.78e-02	1.00e+00	5.802	1	1	25
GO:0007094	mitotic spindle assembly checkpoint	1.78e-02	1.00e+00	5.802	1	4	25
GO:0005654	nucleoplasm	1.91e-02	1.00e+00	2.256	3	68	876
GO:0000278	mitotic cell cycle	1.94e-02	1.00e+00	3.151	2	28	314
GO:0045892	negative regulation of transcription, DNA-templated	1.98e-02	1.00e+00	3.138	2	17	317
GO:0050885	neuromuscular process controlling balance	1.99e-02	1.00e+00	5.639	1	1	28
GO:0042752	regulation of circadian rhythm	2.06e-02	1.00e+00	5.588	1	5	29
GO:0016301	kinase activity	2.13e-02	1.00e+00	5.539	1	2	30
GO:0007077	mitotic nuclear envelope disassembly	2.27e-02	1.00e+00	5.446	1	9	32
GO:0000910	cytokinesis	2.34e-02	1.00e+00	5.402	1	2	33
GO:0000786	nucleosome	2.41e-02	1.00e+00	5.359	1	2	34
GO:0030900	forebrain development	2.55e-02	1.00e+00	5.276	1	2	36
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	2.69e-02	1.00e+00	5.198	1	4	38
GO:0004867	serine-type endopeptidase inhibitor activity	2.97e-02	1.00e+00	5.054	1	1	42
GO:0001047	core promoter binding	2.97e-02	1.00e+00	5.054	1	4	42
GO:0008203	cholesterol metabolic process	3.32e-02	1.00e+00	4.891	1	2	47
GO:0007626	locomotory behavior	3.32e-02	1.00e+00	4.891	1	1	47
GO:0006310	DNA recombination	3.53e-02	1.00e+00	4.802	1	8	50
GO:0006334	nucleosome assembly	3.60e-02	1.00e+00	4.774	1	4	51
GO:0018105	peptidyl-serine phosphorylation	3.60e-02	1.00e+00	4.774	1	2	51
GO:0000776	kinetochore	3.88e-02	1.00e+00	4.665	1	8	55
GO:0006338	chromatin remodeling	3.88e-02	1.00e+00	4.665	1	7	55
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.95e-02	1.00e+00	4.639	1	5	56
GO:0042826	histone deacetylase binding	4.09e-02	1.00e+00	4.588	1	5	58
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.22e-02	1.00e+00	4.539	1	5	60
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	4.57e-02	1.00e+00	4.424	1	7	65
GO:0000922	spindle pole	4.78e-02	1.00e+00	4.359	1	4	68
GO:0010951	negative regulation of endopeptidase activity	4.98e-02	1.00e+00	4.296	1	2	71
GO:0051726	regulation of cell cycle	5.12e-02	1.00e+00	4.256	1	3	73
GO:0030496	midbody	5.12e-02	1.00e+00	4.256	1	6	73
GO:0016363	nuclear matrix	5.12e-02	1.00e+00	4.256	1	10	73
GO:0015630	microtubule cytoskeleton	5.26e-02	1.00e+00	4.217	1	5	75
GO:0071456	cellular response to hypoxia	5.32e-02	1.00e+00	4.198	1	2	76
GO:0005819	spindle	5.60e-02	1.00e+00	4.124	1	6	80
GO:0008201	heparin binding	6.35e-02	1.00e+00	3.938	1	4	91
GO:0000086	G2/M transition of mitotic cell cycle	6.75e-02	1.00e+00	3.846	1	7	97
GO:0008017	microtubule binding	6.75e-02	1.00e+00	3.846	1	9	97
GO:0006397	mRNA processing	7.63e-02	1.00e+00	3.665	1	12	110
GO:0004672	protein kinase activity	8.63e-02	1.00e+00	3.480	1	5	125
GO:0044212	transcription regulatory region DNA binding	9.81e-02	1.00e+00	3.286	1	13	143
GO:0007067	mitotic nuclear division	1.12e-01	1.00e+00	3.080	1	9	165
GO:0008380	RNA splicing	1.12e-01	1.00e+00	3.080	1	21	165
GO:0005515	protein binding	1.19e-01	1.00e+00	0.758	5	198	4124
GO:0000166	nucleotide binding	1.20e-01	1.00e+00	2.987	1	13	176
GO:0004842	ubiquitin-protein transferase activity	1.22e-01	1.00e+00	2.962	1	17	179
GO:0004674	protein serine/threonine kinase activity	1.33e-01	1.00e+00	2.824	1	8	197
GO:0030154	cell differentiation	1.37e-01	1.00e+00	2.774	1	5	204
GO:0006281	DNA repair	1.37e-01	1.00e+00	2.781	1	24	203
GO:0003677	DNA binding	1.42e-01	1.00e+00	1.559	2	52	947
GO:0005813	centrosome	1.46e-01	1.00e+00	2.684	1	10	217
GO:0030198	extracellular matrix organization	1.48e-01	1.00e+00	2.658	1	7	221
GO:0007186	G-protein coupled receptor signaling pathway	1.53e-01	1.00e+00	2.607	1	4	229
GO:0019901	protein kinase binding	1.55e-01	1.00e+00	2.588	1	8	232
GO:0008283	cell proliferation	1.59e-01	1.00e+00	2.545	1	8	239
GO:0005634	nucleus	1.72e-01	1.00e+00	0.782	4	158	3246
GO:0006351	transcription, DNA-templated	1.75e-01	1.00e+00	1.375	2	47	1076
GO:0006508	proteolysis	1.75e-01	1.00e+00	2.402	1	11	264
GO:0046982	protein heterodimerization activity	1.75e-01	1.00e+00	2.396	1	11	265
GO:0006468	protein phosphorylation	1.97e-01	1.00e+00	2.212	1	6	301
GO:0043066	negative regulation of apoptotic process	2.09e-01	1.00e+00	2.115	1	8	322
GO:0042802	identical protein binding	2.28e-01	1.00e+00	1.978	1	15	354
GO:0016032	viral process	2.69e-01	1.00e+00	1.705	1	30	428
GO:0005829	cytosol	3.76e-01	1.00e+00	0.643	2	88	1787
GO:0008270	zinc ion binding	4.18e-01	1.00e+00	0.940	1	39	727
GO:0044822	poly(A) RNA binding	4.50e-01	1.00e+00	0.804	1	45	799
GO:0005524	ATP binding	4.89e-01	1.00e+00	0.645	1	37	892
GO:0016020	membrane	6.03e-01	1.00e+00	0.209	1	56	1207
GO:0005737	cytoplasm	6.03e-01	1.00e+00	0.084	2	127	2633
GO:0005730	nucleolus	6.06e-01	1.00e+00	0.197	1	74	1217
GO:0016021	integral component of membrane	6.96e-01	1.00e+00	-0.129	1	19	1526
GO:0070062	extracellular vesicular exosome	7.24e-01	1.00e+00	-0.234	1	51	1641
GO:0005886	plasma membrane	7.57e-01	1.00e+00	-0.355	1	46	1784

chia-Fav

reg-snw-5347

Statistics

Genes (7)

Interactions (6)

Related GO terms (125)