reg-snw-516

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.291 9.72e-08 2.63e-02 2.07e-02
chia-screen-data-Fav-reg-snw-516 subnetwork

Genes (5)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
[ ATP5G1 ] 516 1-1.1242.2912---
CLPP 8192 4-2.2002.29110-Yes-
COPS6 10980 4-1.7652.39318TF--
GPS1 2873 86-3.6212.68936TFYesYes
PHB 5245 82-2.7432.68936-YesYes

Interactions (4)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
ATP5G1 516 COPS6 10980 pd < reg.ITFP.txt: no annot
GPS1 2873 CLPP 8192 pd > reg.ITFP.txt: no annot
CLPP 8192 COPS6 10980 pd < reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot

Related GO terms (54)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0010388cullin deneddylation5.87e-065.73e-028.931248
GO:0008180COP9 signalosome5.76e-055.63e-017.3472624
GO:0009368endopeptidase Clp complex1.02e-031.00e+009.931112
GO:0045263proton-transporting ATP synthase complex, coupling factor F(o)1.54e-031.00e+009.347113
GO:2000323negative regulation of glucocorticoid receptor signaling pathway2.56e-031.00e+008.610115
GO:0005739mitochondrion2.76e-031.00e+003.152332659
GO:0050847progesterone receptor signaling pathway3.07e-031.00e+008.347126
GO:0005743mitochondrial inner membrane3.89e-031.00e+004.30929197
GO:0010944negative regulation of transcription by competitive promoter binding4.09e-031.00e+007.931118
GO:0071354cellular response to interleukin-64.60e-031.00e+007.762119
GO:0005095GTPase inhibitor activity5.11e-031.00e+007.6101110
GO:0042776mitochondrial ATP synthesis coupled proton transport5.62e-031.00e+007.4721211
GO:0060766negative regulation of androgen receptor signaling pathway5.62e-031.00e+007.4721411
GO:0015078hydrogen ion transmembrane transporter activity5.62e-031.00e+007.4721111
GO:0051603proteolysis involved in cellular protein catabolic process6.13e-031.00e+007.3471112
GO:0016575histone deacetylation7.15e-031.00e+007.1241214
GO:0000188inactivation of MAPK activity7.66e-031.00e+007.0251115
GO:0005753mitochondrial proton-transporting ATP synthase complex7.66e-031.00e+007.0251115
GO:0015991ATP hydrolysis coupled proton transport7.66e-031.00e+007.0251115
GO:0071897DNA biosynthetic process1.02e-021.00e+006.6101220
GO:0008233peptidase activity1.43e-021.00e+006.1241228
GO:0007254JNK cascade1.73e-021.00e+005.8441134
GO:0022904respiratory electron transport chain2.74e-021.00e+005.1771354
GO:0042826histone deacetylase binding2.94e-021.00e+005.0731558
GO:0030308negative regulation of cell growth3.53e-021.00e+004.8021370
GO:0008289lipid binding3.68e-021.00e+004.7421473
GO:0001649osteoblast differentiation3.73e-021.00e+004.7221574
GO:0044237cellular metabolic process3.78e-021.00e+004.7031375
GO:0004252serine-type endopeptidase activity3.93e-021.00e+004.6461178
GO:0005215transporter activity4.13e-021.00e+004.5741582
GO:0051260protein homooligomerization4.38e-021.00e+004.4891287
GO:0042981regulation of apoptotic process5.61e-021.00e+004.12414112
GO:0007049cell cycle5.75e-021.00e+004.08618115
GO:0005759mitochondrial matrix6.92e-021.00e+003.81317139
GO:0044212transcription regulatory region DNA binding7.11e-021.00e+003.772113143
GO:0019899enzyme binding1.03e-011.00e+003.21717210
GO:0005515protein binding1.05e-011.00e+000.92241984124
GO:0005737cytoplasm1.25e-011.00e+001.15431272633
GO:0008285negative regulation of cell proliferation1.34e-011.00e+002.818111277
GO:0045892negative regulation of transcription, DNA-templated1.52e-011.00e+002.623117317
GO:0042802identical protein binding1.69e-011.00e+002.464115354
GO:0045893positive regulation of transcription, DNA-templated1.79e-011.00e+002.373121377
GO:0070062extracellular vesicular exosome1.99e-011.00e+001.2512511641
GO:0016032viral process2.01e-011.00e+002.190130428
GO:0005634nucleus2.08e-011.00e+000.85231583246
GO:0000122negative regulation of transcription from RNA polymerase II promoter2.13e-011.00e+002.099129456
GO:0005887integral component of plasma membrane2.62e-011.00e+001.76418575
GO:0007165signal transduction2.79e-011.00e+001.660124618
GO:0006355regulation of transcription, DNA-templated3.16e-011.00e+001.450131715
GO:0044281small molecule metabolic process3.64e-011.00e+001.210135844
GO:0005654nucleoplasm3.75e-011.00e+001.157168876
GO:0016020membrane4.83e-011.00e+000.6941561207
GO:0005730nucleolus4.86e-011.00e+000.6821741217
GO:0016021integral component of membrane5.73e-011.00e+000.3561191526