reg-snw-26001

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.290	9.73e-08	2.63e-02	2.07e-02

chia-screen-data-Fav-reg-snw-26001 subnetwork

Genes (10)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
RNF40	9810	10	-2.082	2.492	38	TF	Yes	-
NMUR2	56923	3	-2.215	2.290	33	-	Yes	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
[ RNF167 ]	26001	1	-1.178	2.290	6	TF	-	-
KLC3	147700	7	-2.130	2.290	132	TF	Yes	-
LCE1E	353135	7	-2.428	2.414	31	-	Yes	Yes
C16orf13	84326	12	-2.090	2.492	36	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
DRG2	1819	15	-2.526	2.492	11	-	Yes	-
SYMPK	8189	11	-1.890	2.492	51	TF	-	-

Interactions (9)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
DRG2	1819	SYMPK	8189	pd	<	reg.ITFP.txt: no annot
SYMPK	8189	C16orf13	84326	pd	>	reg.ITFP.txt: no annot
RNF40	9810	RNF167	26001	pd	<>	reg.ITFP.txt: no annot
RNF40	9810	KLC3	147700	pd	<>	reg.ITFP.txt: no annot
NMUR2	56923	KLC3	147700	pd	<	reg.ITFP.txt: no annot
KLC3	147700	LCE1E	353135	pd	>	reg.ITFP.txt: no annot
GPS1	2873	C16orf13	84326	pd	>	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
SYMPK	8189	RNF40	9810	pd	<>	reg.ITFP.txt: no annot

Related GO terms (90)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0001607	neuromedin U receptor activity	1.02e-03	1.00e+00	9.931	1	1	1
GO:0042924	neuromedin U binding	1.02e-03	1.00e+00	9.931	1	1	1
GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling	2.05e-03	1.00e+00	8.931	1	1	2
GO:0002023	reduction of food intake in response to dietary excess	2.05e-03	1.00e+00	8.931	1	1	2
GO:0033503	HULC complex	4.09e-03	1.00e+00	7.931	1	1	4
GO:0005229	intracellular calcium activated chloride channel activity	5.11e-03	1.00e+00	7.610	1	1	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	5.11e-03	1.00e+00	7.610	1	1	5
GO:0043005	neuron projection	5.62e-03	1.00e+00	4.111	2	6	113
GO:0050847	progesterone receptor signaling pathway	6.13e-03	1.00e+00	7.347	1	2	6
GO:0048016	inositol phosphate-mediated signaling	7.15e-03	1.00e+00	7.124	1	1	7
GO:0033523	histone H2B ubiquitination	7.15e-03	1.00e+00	7.124	1	1	7
GO:0010944	negative regulation of transcription by competitive promoter binding	8.17e-03	1.00e+00	6.931	1	1	8
GO:0008088	axon cargo transport	8.17e-03	1.00e+00	6.931	1	1	8
GO:0010388	cullin deneddylation	8.17e-03	1.00e+00	6.931	1	4	8
GO:0006940	regulation of smooth muscle contraction	8.17e-03	1.00e+00	6.931	1	1	8
GO:0050482	arachidonic acid secretion	8.17e-03	1.00e+00	6.931	1	1	8
GO:0010390	histone monoubiquitination	8.17e-03	1.00e+00	6.931	1	2	8
GO:0007625	grooming behavior	9.18e-03	1.00e+00	6.762	1	1	9
GO:0071354	cellular response to interleukin-6	9.18e-03	1.00e+00	6.762	1	1	9
GO:0035253	ciliary rootlet	9.18e-03	1.00e+00	6.762	1	1	9
GO:0016874	ligase activity	9.24e-03	1.00e+00	3.742	2	11	146
GO:0005095	GTPase inhibitor activity	1.02e-02	1.00e+00	6.610	1	1	10
GO:0035307	positive regulation of protein dephosphorylation	1.02e-02	1.00e+00	6.610	1	1	10
GO:0060766	negative regulation of androgen receptor signaling pathway	1.12e-02	1.00e+00	6.472	1	4	11
GO:0017075	syntaxin-1 binding	1.32e-02	1.00e+00	6.231	1	1	13
GO:0004842	ubiquitin-protein transferase activity	1.37e-02	1.00e+00	3.448	2	17	179
GO:0016575	histone deacetylation	1.43e-02	1.00e+00	6.124	1	2	14
GO:0031514	motile cilium	1.43e-02	1.00e+00	6.124	1	1	14
GO:0000188	inactivation of MAPK activity	1.53e-02	1.00e+00	6.025	1	1	15
GO:0048265	response to pain	1.63e-02	1.00e+00	5.931	1	1	16
GO:0005525	GTP binding	1.64e-02	1.00e+00	3.309	2	12	197
GO:0007631	feeding behavior	1.73e-02	1.00e+00	5.844	1	1	17
GO:0006378	mRNA polyadenylation	1.83e-02	1.00e+00	5.762	1	3	18
GO:0071897	DNA biosynthetic process	2.03e-02	1.00e+00	5.610	1	2	20
GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway	2.13e-02	1.00e+00	5.539	1	1	21
GO:0019894	kinesin binding	2.13e-02	1.00e+00	5.539	1	1	21
GO:0019722	calcium-mediated signaling	2.23e-02	1.00e+00	5.472	1	1	22
GO:0031424	keratinization	2.33e-02	1.00e+00	5.408	1	2	23
GO:0006821	chloride transport	2.33e-02	1.00e+00	5.408	1	2	23
GO:0008180	COP9 signalosome	2.43e-02	1.00e+00	5.347	1	6	24
GO:0005737	cytoplasm	2.85e-02	1.00e+00	1.154	6	127	2633
GO:0045786	negative regulation of cell cycle	3.03e-02	1.00e+00	5.025	1	3	30
GO:0005871	kinesin complex	3.13e-02	1.00e+00	4.977	1	3	31
GO:0007254	JNK cascade	3.43e-02	1.00e+00	4.844	1	1	34
GO:0012505	endomembrane system	3.43e-02	1.00e+00	4.844	1	2	34
GO:1902476	chloride transmembrane transport	3.63e-02	1.00e+00	4.762	1	2	36
GO:0003777	microtubule motor activity	3.92e-02	1.00e+00	4.646	1	3	39
GO:0000151	ubiquitin ligase complex	4.81e-02	1.00e+00	4.347	1	4	48
GO:0007218	neuropeptide signaling pathway	5.30e-02	1.00e+00	4.204	1	2	53
GO:0006816	calcium ion transport	5.30e-02	1.00e+00	4.204	1	1	53
GO:0042826	histone deacetylase binding	5.79e-02	1.00e+00	4.073	1	5	58
GO:0007417	central nervous system development	6.27e-02	1.00e+00	3.954	1	2	63
GO:0005923	tight junction	6.37e-02	1.00e+00	3.931	1	2	64
GO:0007204	positive regulation of cytosolic calcium ion concentration	6.37e-02	1.00e+00	3.931	1	1	64
GO:0030308	negative regulation of cell growth	6.94e-02	1.00e+00	3.802	1	3	70
GO:0001649	osteoblast differentiation	7.33e-02	1.00e+00	3.722	1	5	74
GO:0006511	ubiquitin-dependent protein catabolic process	9.04e-02	1.00e+00	3.408	1	6	92
GO:0000209	protein polyubiquitination	9.04e-02	1.00e+00	3.408	1	6	92
GO:0008017	microtubule binding	9.51e-02	1.00e+00	3.332	1	9	97
GO:0042981	regulation of apoptotic process	1.09e-01	1.00e+00	3.124	1	4	112
GO:0007049	cell cycle	1.12e-01	1.00e+00	3.086	1	8	115
GO:0016020	membrane	1.16e-01	1.00e+00	1.279	3	56	1207
GO:0004930	G-protein coupled receptor activity	1.20e-01	1.00e+00	2.977	1	2	124
GO:0032403	protein complex binding	1.25e-01	1.00e+00	2.909	1	5	130
GO:0007165	signal transduction	1.28e-01	1.00e+00	1.660	2	24	618
GO:0031625	ubiquitin protein ligase binding	1.33e-01	1.00e+00	2.823	1	7	138
GO:0044212	transcription regulatory region DNA binding	1.37e-01	1.00e+00	2.772	1	13	143
GO:0007267	cell-cell signaling	1.42e-01	1.00e+00	2.722	1	1	148
GO:0005739	mitochondrion	1.43e-01	1.00e+00	1.567	2	32	659
GO:0005874	microtubule	1.55e-01	1.00e+00	2.583	1	10	163
GO:0008270	zinc ion binding	1.68e-01	1.00e+00	1.426	2	39	727
GO:0008152	metabolic process	1.72e-01	1.00e+00	2.424	1	6	182
GO:0005856	cytoskeleton	1.78e-01	1.00e+00	2.362	1	8	190
GO:0005743	mitochondrial inner membrane	1.84e-01	1.00e+00	2.309	1	9	197
GO:0019899	enzyme binding	1.95e-01	1.00e+00	2.217	1	7	210
GO:0005654	nucleoplasm	2.24e-01	1.00e+00	1.157	2	68	876
GO:0007155	cell adhesion	2.24e-01	1.00e+00	2.001	1	8	244
GO:0008285	negative regulation of cell proliferation	2.50e-01	1.00e+00	1.818	1	11	277
GO:0045892	negative regulation of transcription, DNA-templated	2.81e-01	1.00e+00	1.623	1	17	317
GO:0045893	positive regulation of transcription, DNA-templated	3.26e-01	1.00e+00	1.373	1	21	377
GO:0042803	protein homodimerization activity	3.61e-01	1.00e+00	1.190	1	13	428
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.80e-01	1.00e+00	1.099	1	29	456
GO:0005515	protein binding	4.24e-01	1.00e+00	0.244	5	198	4124
GO:0005634	nucleus	4.38e-01	1.00e+00	0.267	4	158	3246
GO:0005887	integral component of plasma membrane	4.55e-01	1.00e+00	0.764	1	8	575
GO:0016021	integral component of membrane	4.79e-01	1.00e+00	0.356	2	19	1526
GO:0006355	regulation of transcription, DNA-templated	5.33e-01	1.00e+00	0.450	1	31	715
GO:0005886	plasma membrane	5.70e-01	1.00e+00	0.131	2	46	1784
GO:0005730	nucleolus	7.36e-01	1.00e+00	-0.318	1	74	1217
GO:0070062	extracellular vesicular exosome	8.41e-01	1.00e+00	-0.749	1	51	1641

chia-Fav

reg-snw-26001

Statistics

Genes (10)

Interactions (9)

Related GO terms (90)