meta-reg-snw-27130

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
int-snw-90019	chia-screen-data-Fav	2.833	1.75e-15	4.97e-04	3.45e-03	12	11
reg-snw-27130	chia-screen-data-Fav	2.286	1.02e-07	2.70e-02	2.12e-02	18	13

chia-screen-data-Fav-meta-reg-snw-27130 subnetwork

Genes (26)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
NDUFA4L2	56901	10	-2.477	2.459	21	Yes	-
PHB	5245	12	-2.743	2.689	163	Yes	Yes
YAP1	10413	12	-4.256	3.538	53	Yes	-
VARS	7407	8	-2.366	2.689	204	Yes	-
SCD	6319	2	-1.715	2.286	82	-	-
APC	324	6	-2.293	3.004	384	Yes	-
POU5F1	5460	12	-5.148	3.538	179	Yes	Yes
NUP160	23279	2	-1.529	2.387	50	-	-
INVS	27130	2	-1.140	2.286	29	-	-
FBXO22	26263	8	-1.739	2.459	208	-	-
ULK2	9706	3	-2.292	3.197	312	Yes	Yes
TPR	7175	3	-2.638	2.445	64	Yes	Yes
EPRS	2058	2	-1.286	2.286	139	-	-
NCBP1	4686	8	-2.510	2.459	84	Yes	Yes
EIF2S2	8894	9	-2.999	2.459	103	Yes	Yes
SYNCRIP	10492	8	-2.401	2.503	247	Yes	Yes
HNRNPD	3184	3	-2.153	3.117	123	Yes	-
CENPQ	55166	2	-2.137	2.459	16	Yes	-
SRSF3	6428	5	-2.992	3.538	54	Yes	-
CCT7	10574	10	-2.335	2.459	173	Yes	-
HNRNPU	3192	12	-2.869	2.644	172	Yes	-
GPS1	2873	10	-3.621	2.689	62	Yes	Yes
POLH	5429	8	-2.586	2.459	24	Yes	Yes
DDIT3	1649	11	-2.825	3.504	343	Yes	Yes
SYT8	90019	3	-1.382	2.833	1	-	-
PSPH	5723	2	-2.063	2.387	11	Yes	-

Interactions (42)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
EPRS	2058	HNRNPU	3192	pd	>	reg.ITFP.txt: no annot
NCBP1	4686	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
PHB	5245	VARS	7407	pd	<	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
APC	324	CCT7	10574	pp	--	int.I2D: Jorgensen_EphR, SOURAV_MAPK_LOW, IntAct
APC	324	PHB	5245	pp	--	int.I2D: Jorgensen_EphR
ULK2	9706	SYNCRIP	10492	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
NCBP1	4686	TPR	7175	pd	<	reg.ITFP.txt: no annot
NUP160	23279	INVS	27130	pd	<	reg.ITFP.txt: no annot
POLH	5429	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
EPRS	2058	NUP160	23279	pd	>	reg.ITFP.txt: no annot
APC	324	TPR	7175	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid, IntAct, SOURAV_MAPK_HIGH
EPRS	2058	CCT7	10574	pd	>	reg.ITFP.txt: no annot
EPRS	2058	INVS	27130	pd	<>	reg.ITFP.txt: no annot
HNRNPD	3184	ULK2	9706	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
CCT7	10574	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
PSPH	5723	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
HNRNPU	3192	ULK2	9706	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
DDIT3	1649	HNRNPU	3192	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
SCD	6319	INVS	27130	pd	<	reg.ITFP.txt: no annot
POU5F1	5460	SRSF3	6428	pp	--	int.I2D: BioGrid
NUP160	23279	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
DDIT3	1649	VARS	7407	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
NCBP1	4686	INVS	27130	pd	<	reg.ITFP.txt: no annot
HNRNPD	3184	HNRNPU	3192	pp	--	int.Mint: MI:0915(physical association)
EPRS	2058	NCBP1	4686	pd	>	reg.ITFP.txt: no annot
EPRS	2058	SYNCRIP	10492	pd	<>	reg.ITFP.txt: no annot
EPRS	2058	SYNCRIP	10492	pp	--	int.Intact: MI:0915(physical association); int.I2D: BCI, HPRD; int.HPRD: in vivo
SRSF3	6428	ULK2	9706	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
FBXO22	26263	INVS	27130	pd	<>	reg.ITFP.txt: no annot
EPRS	2058	SCD	6319	pd	>	reg.ITFP.txt: no annot
FBXO22	26263	CENPQ	55166	pd	>	reg.ITFP.txt: no annot
HNRNPD	3184	SYNCRIP	10492	pp	--	int.I2D: HPRD, BCI; int.HPRD: in vivo
VARS	7407	FBXO22	26263	pd	<>	reg.ITFP.txt: no annot
PHB	5245	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
HNRNPU	3192	SYNCRIP	10492	pp	--	int.Mint: MI:0915(physical association)
FBXO22	26263	NDUFA4L2	56901	pd	>	reg.ITFP.txt: no annot
APC	324	SYNCRIP	10492	pp	--	int.I2D: Jorgensen_EphR
DDIT3	1649	HNRNPD	3184	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
EIF2S2	8894	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
SYNCRIP	10492	SYT8	90019	pp	--	int.I2D: BioGrid, HPRD; int.HPRD: in vitro, in vivo

Related GO terms (352)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005654	nucleoplasm	3.14e-08	5.12e-04	2.782	12	31	1095
GO:0030529	ribonucleoprotein complex	8.91e-07	1.45e-02	4.783	5	6	114
GO:0000398	mRNA splicing, via spliceosome	5.51e-06	8.99e-02	4.250	5	9	165
GO:0010467	gene expression	6.19e-06	1.01e-01	2.908	8	27	669
GO:0005829	cytosol	7.86e-06	1.28e-01	1.778	14	38	2562
GO:0097452	GAIT complex	1.46e-05	2.39e-01	8.294	2	2	4
GO:0003723	RNA binding	1.62e-05	2.64e-01	3.407	6	15	355
GO:0070934	CRD-mediated mRNA stabilization	2.43e-05	3.97e-01	7.972	2	2	5
GO:0008380	RNA splicing	2.87e-05	4.68e-01	3.758	5	14	232
GO:0070937	CRD-mediated mRNA stability complex	3.65e-05	5.95e-01	7.709	2	2	6
GO:0006396	RNA processing	1.16e-04	1.00e+00	4.972	3	4	60
GO:0006406	mRNA export from nucleus	1.28e-04	1.00e+00	4.925	3	5	62
GO:0000776	kinetochore	1.34e-04	1.00e+00	4.902	3	4	63
GO:0044212	transcription regulatory region DNA binding	1.45e-04	1.00e+00	3.876	4	5	171
GO:0042789	mRNA transcription from RNA polymerase II promoter	1.88e-04	1.00e+00	6.594	2	2	13
GO:0044822	poly(A) RNA binding	1.89e-04	1.00e+00	2.220	8	27	1078
GO:0005487	nucleocytoplasmic transporter activity	2.19e-04	1.00e+00	6.487	2	2	14
GO:0005515	protein binding	2.49e-04	1.00e+00	0.961	19	77	6127
GO:0090090	negative regulation of canonical Wnt signaling pathway	3.60e-04	1.00e+00	4.420	3	4	88
GO:0001649	osteoblast differentiation	4.51e-04	1.00e+00	4.309	3	3	95
GO:0071346	cellular response to interferon-gamma	6.05e-04	1.00e+00	5.770	2	2	23
GO:0010827	regulation of glucose transport	1.10e-03	1.00e+00	5.340	2	3	31
GO:0007094	mitotic spindle assembly checkpoint	1.10e-03	1.00e+00	5.340	2	3	31
GO:0042594	response to starvation	1.18e-03	1.00e+00	5.294	2	3	32
GO:0007077	mitotic nuclear envelope disassembly	1.57e-03	1.00e+00	5.085	2	3	37
GO:1901673	regulation of spindle assembly involved in mitosis	1.59e-03	1.00e+00	9.294	1	1	1
GO:0043578	nuclear matrix organization	1.59e-03	1.00e+00	9.294	1	1	1
GO:2000016	negative regulation of determination of dorsal identity	1.59e-03	1.00e+00	9.294	1	1	1
GO:0010965	regulation of mitotic sister chromatid separation	1.59e-03	1.00e+00	9.294	1	1	1
GO:0006404	RNA import into nucleus	1.59e-03	1.00e+00	9.294	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	1.59e-03	1.00e+00	9.294	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	1.59e-03	1.00e+00	9.294	1	1	1
GO:0042483	negative regulation of odontogenesis	1.59e-03	1.00e+00	9.294	1	1	1
GO:0060795	cell fate commitment involved in formation of primary germ layer	1.59e-03	1.00e+00	9.294	1	1	1
GO:0051171	regulation of nitrogen compound metabolic process	1.59e-03	1.00e+00	9.294	1	1	1
GO:0031453	positive regulation of heterochromatin assembly	1.59e-03	1.00e+00	9.294	1	1	1
GO:0035019	somatic stem cell maintenance	1.83e-03	1.00e+00	4.972	2	2	40
GO:0017148	negative regulation of translation	1.93e-03	1.00e+00	4.936	2	3	41
GO:0006974	cellular response to DNA damage stimulus	1.97e-03	1.00e+00	3.575	3	4	158
GO:0006418	tRNA aminoacylation for protein translation	2.02e-03	1.00e+00	4.902	2	3	42
GO:0008645	hexose transport	2.02e-03	1.00e+00	4.902	2	3	42
GO:0031124	mRNA 3'-end processing	2.02e-03	1.00e+00	4.902	2	4	42
GO:0006369	termination of RNA polymerase II transcription	2.32e-03	1.00e+00	4.802	2	4	45
GO:0004832	valine-tRNA ligase activity	3.18e-03	1.00e+00	8.294	1	1	2
GO:0060242	contact inhibition	3.18e-03	1.00e+00	8.294	1	1	2
GO:0031990	mRNA export from nucleus in response to heat stress	3.18e-03	1.00e+00	8.294	1	1	2
GO:0044337	canonical Wnt signaling pathway involved in positive regulation of apoptotic process	3.18e-03	1.00e+00	8.294	1	1	2
GO:0004818	glutamate-tRNA ligase activity	3.18e-03	1.00e+00	8.294	1	1	2
GO:0005846	nuclear cap binding complex	3.18e-03	1.00e+00	8.294	1	1	2
GO:0002176	male germ cell proliferation	3.18e-03	1.00e+00	8.294	1	1	2
GO:0006438	valyl-tRNA aminoacylation	3.18e-03	1.00e+00	8.294	1	1	2
GO:0009786	regulation of asymmetric cell division	3.18e-03	1.00e+00	8.294	1	1	2
GO:0070840	dynein complex binding	3.18e-03	1.00e+00	8.294	1	1	2
GO:0060965	negative regulation of gene silencing by miRNA	3.18e-03	1.00e+00	8.294	1	1	2
GO:0046832	negative regulation of RNA export from nucleus	3.18e-03	1.00e+00	8.294	1	1	2
GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	3.18e-03	1.00e+00	8.294	1	1	2
GO:0006424	glutamyl-tRNA aminoacylation	3.18e-03	1.00e+00	8.294	1	1	2
GO:0000189	MAPK import into nucleus	3.18e-03	1.00e+00	8.294	1	1	2
GO:0006433	prolyl-tRNA aminoacylation	3.18e-03	1.00e+00	8.294	1	1	2
GO:0004827	proline-tRNA ligase activity	3.18e-03	1.00e+00	8.294	1	1	2
GO:0009798	axis specification	3.18e-03	1.00e+00	8.294	1	1	2
GO:0044324	regulation of transcription involved in anterior/posterior axis specification	3.18e-03	1.00e+00	8.294	1	1	2
GO:0015758	glucose transport	3.95e-03	1.00e+00	4.411	2	3	59
GO:0005643	nuclear pore	3.95e-03	1.00e+00	4.411	2	3	59
GO:0005737	cytoplasm	4.07e-03	1.00e+00	1.037	13	43	3976
GO:0042306	regulation of protein import into nucleus	4.77e-03	1.00e+00	7.709	1	1	3
GO:0006563	L-serine metabolic process	4.77e-03	1.00e+00	7.709	1	1	3
GO:0005850	eukaryotic translation initiation factor 2 complex	4.77e-03	1.00e+00	7.709	1	2	3
GO:0004768	stearoyl-CoA 9-desaturase activity	4.77e-03	1.00e+00	7.709	1	1	3
GO:0006405	RNA export from nucleus	4.77e-03	1.00e+00	7.709	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	4.77e-03	1.00e+00	7.709	1	1	3
GO:0034273	ATG1/UKL1 signaling complex	6.36e-03	1.00e+00	7.294	1	1	4
GO:0060913	cardiac cell fate determination	6.36e-03	1.00e+00	7.294	1	1	4
GO:0035613	RNA stem-loop binding	6.36e-03	1.00e+00	7.294	1	1	4
GO:0097167	circadian regulation of translation	6.36e-03	1.00e+00	7.294	1	1	4
GO:0006290	pyrimidine dimer repair	6.36e-03	1.00e+00	7.294	1	1	4
GO:0004647	phosphoserine phosphatase activity	6.36e-03	1.00e+00	7.294	1	1	4
GO:0006999	nuclear pore organization	6.36e-03	1.00e+00	7.294	1	1	4
GO:0006564	L-serine biosynthetic process	6.36e-03	1.00e+00	7.294	1	1	4
GO:0044615	nuclear pore nuclear basket	6.36e-03	1.00e+00	7.294	1	1	4
GO:0019887	protein kinase regulator activity	6.36e-03	1.00e+00	7.294	1	1	4
GO:0001822	kidney development	6.97e-03	1.00e+00	3.990	2	2	79
GO:0071013	catalytic step 2 spliceosome	6.97e-03	1.00e+00	3.990	2	3	79
GO:0001714	endodermal cell fate specification	7.94e-03	1.00e+00	6.972	1	1	5
GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process	7.94e-03	1.00e+00	6.972	1	1	5
GO:0043620	regulation of DNA-templated transcription in response to stress	7.94e-03	1.00e+00	6.972	1	1	5
GO:0060971	embryonic heart tube left/right pattern formation	7.94e-03	1.00e+00	6.972	1	1	5
GO:0048742	regulation of skeletal muscle fiber development	7.94e-03	1.00e+00	6.972	1	1	5
GO:0045292	mRNA cis splicing, via spliceosome	7.94e-03	1.00e+00	6.972	1	1	5
GO:0031442	positive regulation of mRNA 3'-end processing	7.94e-03	1.00e+00	6.972	1	1	5
GO:0010793	regulation of mRNA export from nucleus	7.94e-03	1.00e+00	6.972	1	1	5
GO:0048671	negative regulation of collateral sprouting	7.94e-03	1.00e+00	6.972	1	1	5
GO:0070849	response to epidermal growth factor	7.94e-03	1.00e+00	6.972	1	1	5
GO:0005634	nucleus	8.21e-03	1.00e+00	0.864	14	55	4828
GO:0000166	nucleotide binding	8.97e-03	1.00e+00	2.792	3	6	272
GO:0030858	positive regulation of epithelial cell differentiation	9.52e-03	1.00e+00	6.709	1	1	6
GO:0050847	progesterone receptor signaling pathway	9.52e-03	1.00e+00	6.709	1	1	6
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	9.52e-03	1.00e+00	6.709	1	1	6
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	9.52e-03	1.00e+00	6.709	1	1	6
GO:0071204	histone pre-mRNA 3'end processing complex	9.52e-03	1.00e+00	6.709	1	1	6
GO:0016032	viral process	9.93e-03	1.00e+00	2.217	4	16	540
GO:0007091	metaphase/anaphase transition of mitotic cell cycle	1.11e-02	1.00e+00	6.487	1	1	7
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	1.11e-02	1.00e+00	6.487	1	1	7
GO:0046825	regulation of protein export from nucleus	1.11e-02	1.00e+00	6.487	1	2	7
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	1.11e-02	1.00e+00	6.487	1	1	7
GO:0002161	aminoacyl-tRNA editing activity	1.11e-02	1.00e+00	6.487	1	1	7
GO:0006301	postreplication repair	1.11e-02	1.00e+00	6.487	1	1	7
GO:0006282	regulation of DNA repair	1.11e-02	1.00e+00	6.487	1	1	7
GO:0045670	regulation of osteoclast differentiation	1.27e-02	1.00e+00	6.294	1	1	8
GO:0051292	nuclear pore complex assembly	1.27e-02	1.00e+00	6.294	1	1	8
GO:0001955	blood vessel maturation	1.27e-02	1.00e+00	6.294	1	1	8
GO:0000339	RNA cap binding	1.27e-02	1.00e+00	6.294	1	1	8
GO:0035457	cellular response to interferon-alpha	1.27e-02	1.00e+00	6.294	1	1	8
GO:0006461	protein complex assembly	1.34e-02	1.00e+00	3.500	2	2	111
GO:0042405	nuclear inclusion body	1.42e-02	1.00e+00	6.124	1	1	9
GO:0071354	cellular response to interleukin-6	1.42e-02	1.00e+00	6.124	1	1	9
GO:0010388	cullin deneddylation	1.42e-02	1.00e+00	6.124	1	5	9
GO:0006983	ER overload response	1.42e-02	1.00e+00	6.124	1	1	9
GO:0043495	protein anchor	1.42e-02	1.00e+00	6.124	1	1	9
GO:0005832	chaperonin-containing T-complex	1.42e-02	1.00e+00	6.124	1	1	9
GO:0005635	nuclear envelope	1.46e-02	1.00e+00	3.436	2	3	116
GO:0002199	zona pellucida receptor complex	1.58e-02	1.00e+00	5.972	1	1	10
GO:0045667	regulation of osteoblast differentiation	1.58e-02	1.00e+00	5.972	1	1	10
GO:0031274	positive regulation of pseudopodium assembly	1.58e-02	1.00e+00	5.972	1	1	10
GO:0006379	mRNA cleavage	1.58e-02	1.00e+00	5.972	1	2	10
GO:0006450	regulation of translational fidelity	1.58e-02	1.00e+00	5.972	1	1	10
GO:0031080	nuclear pore outer ring	1.58e-02	1.00e+00	5.972	1	1	10
GO:0010225	response to UV-C	1.58e-02	1.00e+00	5.972	1	2	10
GO:0000731	DNA synthesis involved in DNA repair	1.58e-02	1.00e+00	5.972	1	1	10
GO:0010944	negative regulation of transcription by competitive promoter binding	1.58e-02	1.00e+00	5.972	1	1	10
GO:0030877	beta-catenin destruction complex	1.58e-02	1.00e+00	5.972	1	1	10
GO:0007050	cell cycle arrest	1.70e-02	1.00e+00	3.317	2	3	126
GO:0005845	mRNA cap binding complex	1.74e-02	1.00e+00	5.835	1	1	11
GO:0051010	microtubule plus-end binding	1.74e-02	1.00e+00	5.835	1	2	11
GO:0007340	acrosome reaction	1.74e-02	1.00e+00	5.835	1	1	11
GO:0045662	negative regulation of myoblast differentiation	1.74e-02	1.00e+00	5.835	1	1	11
GO:0031116	positive regulation of microtubule polymerization	1.74e-02	1.00e+00	5.835	1	1	11
GO:0035413	positive regulation of catenin import into nucleus	1.74e-02	1.00e+00	5.835	1	1	11
GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.74e-02	1.00e+00	5.835	1	1	11
GO:0042162	telomeric DNA binding	1.74e-02	1.00e+00	5.835	1	1	11
GO:0060391	positive regulation of SMAD protein import into nucleus	1.74e-02	1.00e+00	5.835	1	1	11
GO:0032886	regulation of microtubule-based process	1.90e-02	1.00e+00	5.709	1	1	12
GO:0045947	negative regulation of translational initiation	1.90e-02	1.00e+00	5.709	1	1	12
GO:0008334	histone mRNA metabolic process	1.90e-02	1.00e+00	5.709	1	1	12
GO:0045295	gamma-catenin binding	1.90e-02	1.00e+00	5.709	1	1	12
GO:0034045	pre-autophagosomal structure membrane	1.90e-02	1.00e+00	5.709	1	1	12
GO:0008143	poly(A) binding	1.90e-02	1.00e+00	5.709	1	2	12
GO:0034399	nuclear periphery	1.90e-02	1.00e+00	5.709	1	1	12
GO:0043488	regulation of mRNA stability	2.05e-02	1.00e+00	5.594	1	1	13
GO:0060766	negative regulation of androgen receptor signaling pathway	2.05e-02	1.00e+00	5.594	1	1	13
GO:0044295	axonal growth cone	2.05e-02	1.00e+00	5.594	1	1	13
GO:0051019	mitogen-activated protein kinase binding	2.05e-02	1.00e+00	5.594	1	2	13
GO:0043409	negative regulation of MAPK cascade	2.05e-02	1.00e+00	5.594	1	2	13
GO:0005868	cytoplasmic dynein complex	2.05e-02	1.00e+00	5.594	1	1	13
GO:0035198	miRNA binding	2.05e-02	1.00e+00	5.594	1	1	13
GO:0046827	positive regulation of protein export from nucleus	2.05e-02	1.00e+00	5.594	1	1	13
GO:0016055	Wnt signaling pathway	2.10e-02	1.00e+00	3.154	2	3	141
GO:0035371	microtubule plus-end	2.21e-02	1.00e+00	5.487	1	1	14
GO:0071480	cellular response to gamma radiation	2.21e-02	1.00e+00	5.487	1	1	14
GO:0005095	GTPase inhibitor activity	2.21e-02	1.00e+00	5.487	1	1	14
GO:0005215	transporter activity	2.22e-02	1.00e+00	3.114	2	2	145
GO:0042307	positive regulation of protein import into nucleus	2.36e-02	1.00e+00	5.387	1	2	15
GO:0001824	blastocyst development	2.36e-02	1.00e+00	5.387	1	1	15
GO:0006401	RNA catabolic process	2.36e-02	1.00e+00	5.387	1	1	15
GO:0000278	mitotic cell cycle	2.47e-02	1.00e+00	2.242	3	12	398
GO:0007026	negative regulation of microtubule depolymerization	2.52e-02	1.00e+00	5.294	1	2	16
GO:0046716	muscle cell cellular homeostasis	2.52e-02	1.00e+00	5.294	1	1	16
GO:0051276	chromosome organization	2.52e-02	1.00e+00	5.294	1	2	16
GO:0043274	phospholipase binding	2.68e-02	1.00e+00	5.207	1	1	17
GO:0008652	cellular amino acid biosynthetic process	2.68e-02	1.00e+00	5.207	1	1	17
GO:0006355	regulation of transcription, DNA-templated	2.81e-02	1.00e+00	1.507	5	13	1104
GO:0031122	cytoplasmic microtubule organization	2.83e-02	1.00e+00	5.124	1	1	18
GO:0090316	positive regulation of intracellular protein transport	2.83e-02	1.00e+00	5.124	1	1	18
GO:0006366	transcription from RNA polymerase II promoter	2.92e-02	1.00e+00	2.148	3	14	425
GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	2.99e-02	1.00e+00	5.046	1	2	19
GO:0031667	response to nutrient levels	2.99e-02	1.00e+00	5.046	1	1	19
GO:0003714	transcription corepressor activity	3.27e-02	1.00e+00	2.810	2	5	179
GO:0048675	axon extension	3.29e-02	1.00e+00	4.902	1	1	21
GO:0032757	positive regulation of interleukin-8 production	3.29e-02	1.00e+00	4.902	1	1	21
GO:0009954	proximal/distal pattern formation	3.29e-02	1.00e+00	4.902	1	1	21
GO:0016575	histone deacetylation	3.29e-02	1.00e+00	4.902	1	1	21
GO:0000281	mitotic cytokinesis	3.29e-02	1.00e+00	4.902	1	1	21
GO:0033574	response to testosterone	3.45e-02	1.00e+00	4.835	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	3.45e-02	1.00e+00	4.835	1	1	22
GO:0031016	pancreas development	3.45e-02	1.00e+00	4.835	1	1	22
GO:0010506	regulation of autophagy	3.60e-02	1.00e+00	4.770	1	1	23
GO:0034660	ncRNA metabolic process	3.60e-02	1.00e+00	4.770	1	1	23
GO:0008135	translation factor activity, nucleic acid binding	3.76e-02	1.00e+00	4.709	1	2	24
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	3.76e-02	1.00e+00	4.709	1	1	24
GO:0006611	protein export from nucleus	3.91e-02	1.00e+00	4.650	1	1	25
GO:0045296	cadherin binding	3.91e-02	1.00e+00	4.650	1	1	25
GO:0035329	hippo signaling	4.06e-02	1.00e+00	4.594	1	1	26
GO:0031047	gene silencing by RNA	4.06e-02	1.00e+00	4.594	1	2	26
GO:0000045	autophagic vacuole assembly	4.06e-02	1.00e+00	4.594	1	1	26
GO:0051209	release of sequestered calcium ion into cytosol	4.06e-02	1.00e+00	4.594	1	2	26
GO:0045893	positive regulation of transcription, DNA-templated	4.13e-02	1.00e+00	1.951	3	6	487
GO:0006913	nucleocytoplasmic transport	4.22e-02	1.00e+00	4.539	1	1	27
GO:0000188	inactivation of MAPK activity	4.22e-02	1.00e+00	4.539	1	1	27
GO:0034080	CENP-A containing nucleosome assembly	4.22e-02	1.00e+00	4.539	1	2	27
GO:0000387	spliceosomal snRNP assembly	4.22e-02	1.00e+00	4.539	1	1	27
GO:0007339	binding of sperm to zona pellucida	4.22e-02	1.00e+00	4.539	1	1	27
GO:0044267	cellular protein metabolic process	4.30e-02	1.00e+00	1.928	3	7	495
GO:0015631	tubulin binding	4.52e-02	1.00e+00	4.436	1	1	29
GO:0005913	cell-cell adherens junction	4.52e-02	1.00e+00	4.436	1	1	29
GO:0003887	DNA-directed DNA polymerase activity	4.52e-02	1.00e+00	4.436	1	1	29
GO:0034605	cellular response to heat	4.52e-02	1.00e+00	4.436	1	1	29
GO:0072686	mitotic spindle	4.52e-02	1.00e+00	4.436	1	1	29
GO:0071897	DNA biosynthetic process	4.52e-02	1.00e+00	4.436	1	1	29
GO:0006606	protein import into nucleus	4.67e-02	1.00e+00	4.387	1	1	30
GO:0006370	7-methylguanosine mRNA capping	4.67e-02	1.00e+00	4.387	1	2	30
GO:0031647	regulation of protein stability	4.67e-02	1.00e+00	4.387	1	2	30
GO:0016071	mRNA metabolic process	4.87e-02	1.00e+00	2.493	2	8	223
GO:0009953	dorsal/ventral pattern formation	4.98e-02	1.00e+00	4.294	1	1	32
GO:1903507	negative regulation of nucleic acid-templated transcription	4.98e-02	1.00e+00	4.294	1	1	32
GO:0033077	T cell differentiation in thymus	5.13e-02	1.00e+00	4.250	1	1	33
GO:0031072	heat shock protein binding	5.13e-02	1.00e+00	4.250	1	1	33
GO:0070830	tight junction assembly	5.13e-02	1.00e+00	4.250	1	1	33
GO:0019221	cytokine-mediated signaling pathway	5.15e-02	1.00e+00	2.449	2	3	230
GO:0016020	membrane	5.26e-02	1.00e+00	1.109	6	27	1746
GO:0008180	COP9 signalosome	5.28e-02	1.00e+00	4.207	1	6	34
GO:0001942	hair follicle development	5.43e-02	1.00e+00	4.165	1	1	35
GO:0009267	cellular response to starvation	5.58e-02	1.00e+00	4.124	1	1	36
GO:0048538	thymus development	5.58e-02	1.00e+00	4.124	1	1	36
GO:0006446	regulation of translational initiation	5.58e-02	1.00e+00	4.124	1	2	36
GO:0051084	'de novo' posttranslational protein folding	5.73e-02	1.00e+00	4.085	1	1	37
GO:0042752	regulation of circadian rhythm	5.73e-02	1.00e+00	4.085	1	3	37
GO:0006633	fatty acid biosynthetic process	5.73e-02	1.00e+00	4.085	1	1	37
GO:0008134	transcription factor binding	5.80e-02	1.00e+00	2.351	2	6	246
GO:0016070	RNA metabolic process	5.84e-02	1.00e+00	2.346	2	8	247
GO:0005524	ATP binding	5.94e-02	1.00e+00	1.213	5	13	1354
GO:0051781	positive regulation of cell division	6.04e-02	1.00e+00	4.009	1	1	39
GO:0005874	microtubule	6.31e-02	1.00e+00	2.283	2	3	258
GO:0005881	cytoplasmic microtubule	6.34e-02	1.00e+00	3.936	1	2	41
GO:0045785	positive regulation of cell adhesion	6.34e-02	1.00e+00	3.936	1	1	41
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	6.78e-02	1.00e+00	3.835	1	1	44
GO:0050434	positive regulation of viral transcription	6.78e-02	1.00e+00	3.835	1	2	44
GO:0005975	carbohydrate metabolic process	7.01e-02	1.00e+00	2.196	2	3	274
GO:0016328	lateral plasma membrane	7.08e-02	1.00e+00	3.770	1	1	46
GO:0044297	cell body	7.08e-02	1.00e+00	3.770	1	1	46
GO:0043525	positive regulation of neuron apoptotic process	7.08e-02	1.00e+00	3.770	1	2	46
GO:0019898	extrinsic component of membrane	7.08e-02	1.00e+00	3.770	1	1	46
GO:0045727	positive regulation of translation	7.08e-02	1.00e+00	3.770	1	2	46
GO:0006921	cellular component disassembly involved in execution phase of apoptosis	7.23e-02	1.00e+00	3.739	1	1	47
GO:0003743	translation initiation factor activity	7.53e-02	1.00e+00	3.679	1	5	49
GO:0045111	intermediate filament cytoskeleton	7.53e-02	1.00e+00	3.679	1	1	49
GO:0006986	response to unfolded protein	7.82e-02	1.00e+00	3.622	1	2	51
GO:0001669	acrosomal vesicle	7.82e-02	1.00e+00	3.622	1	1	51
GO:0007254	JNK cascade	7.82e-02	1.00e+00	3.622	1	2	51
GO:0003684	damaged DNA binding	7.82e-02	1.00e+00	3.622	1	1	51
GO:0045732	positive regulation of protein catabolic process	7.82e-02	1.00e+00	3.622	1	1	51
GO:0000775	chromosome, centromeric region	7.97e-02	1.00e+00	3.594	1	3	52
GO:0034976	response to endoplasmic reticulum stress	7.97e-02	1.00e+00	3.594	1	1	52
GO:0045454	cell redox homeostasis	7.97e-02	1.00e+00	3.594	1	1	52
GO:0009611	response to wounding	8.12e-02	1.00e+00	3.566	1	1	53
GO:0060041	retina development in camera-type eye	8.12e-02	1.00e+00	3.566	1	1	53
GO:0005739	mitochondrion	8.15e-02	1.00e+00	1.263	4	16	1046
GO:0009612	response to mechanical stimulus	8.26e-02	1.00e+00	3.539	1	1	54
GO:0048306	calcium-dependent protein binding	8.70e-02	1.00e+00	3.461	1	1	57
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	8.99e-02	1.00e+00	3.411	1	2	59
GO:0008013	beta-catenin binding	9.14e-02	1.00e+00	3.387	1	4	60
GO:0006987	activation of signaling protein activity involved in unfolded protein response	9.43e-02	1.00e+00	3.340	1	2	62
GO:0007409	axonogenesis	1.00e-01	1.00e+00	3.250	1	1	66
GO:0006368	transcription elongation from RNA polymerase II promoter	1.02e-01	1.00e+00	3.228	1	3	67
GO:0032587	ruffle membrane	1.09e-01	1.00e+00	3.124	1	1	72
GO:0010468	regulation of gene expression	1.09e-01	1.00e+00	3.124	1	1	72
GO:0008021	synaptic vesicle	1.10e-01	1.00e+00	3.104	1	2	73
GO:0003729	mRNA binding	1.10e-01	1.00e+00	3.104	1	3	73
GO:0042826	histone deacetylase binding	1.12e-01	1.00e+00	3.085	1	2	74
GO:0009791	post-embryonic development	1.13e-01	1.00e+00	3.065	1	1	75
GO:0060070	canonical Wnt signaling pathway	1.13e-01	1.00e+00	3.065	1	2	75
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	1.14e-01	1.00e+00	3.046	1	2	76
GO:0043565	sequence-specific DNA binding	1.14e-01	1.00e+00	1.782	2	3	365
GO:0008285	negative regulation of cell proliferation	1.15e-01	1.00e+00	1.774	2	4	367
GO:0008584	male gonad development	1.16e-01	1.00e+00	3.027	1	1	77
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	1.16e-01	1.00e+00	3.027	1	2	77
GO:0006334	nucleosome assembly	1.19e-01	1.00e+00	2.990	1	3	79
GO:0030968	endoplasmic reticulum unfolded protein response	1.21e-01	1.00e+00	2.954	1	2	81
GO:0009952	anterior/posterior pattern specification	1.26e-01	1.00e+00	2.902	1	2	84
GO:0005929	cilium	1.26e-01	1.00e+00	2.902	1	1	84
GO:0009653	anatomical structure morphogenesis	1.30e-01	1.00e+00	2.851	1	1	87
GO:0006464	cellular protein modification process	1.33e-01	1.00e+00	2.818	1	1	89
GO:0005923	tight junction	1.37e-01	1.00e+00	2.770	1	1	92
GO:0005770	late endosome	1.40e-01	1.00e+00	2.739	1	1	94
GO:0016311	dephosphorylation	1.40e-01	1.00e+00	2.739	1	1	94
GO:0051082	unfolded protein binding	1.41e-01	1.00e+00	2.724	1	3	95
GO:0030018	Z disc	1.45e-01	1.00e+00	2.679	1	2	98
GO:0045892	negative regulation of transcription, DNA-templated	1.46e-01	1.00e+00	1.566	2	7	424
GO:0030659	cytoplasmic vesicle membrane	1.57e-01	1.00e+00	2.553	1	1	107
GO:0030308	negative regulation of cell growth	1.65e-01	1.00e+00	2.474	1	2	113
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.67e-01	1.00e+00	2.461	1	3	114
GO:0005819	spindle	1.67e-01	1.00e+00	2.461	1	2	114
GO:0000209	protein polyubiquitination	1.69e-01	1.00e+00	2.436	1	5	116
GO:0006260	DNA replication	1.81e-01	1.00e+00	2.328	1	4	125
GO:0005506	iron ion binding	1.84e-01	1.00e+00	2.305	1	1	127
GO:0006511	ubiquitin-dependent protein catabolic process	1.84e-01	1.00e+00	2.305	1	3	127
GO:0030027	lamellipodium	1.88e-01	1.00e+00	2.272	1	1	130
GO:0030335	positive regulation of cell migration	1.88e-01	1.00e+00	2.272	1	2	130
GO:0006413	translational initiation	1.89e-01	1.00e+00	2.261	1	4	131
GO:0016477	cell migration	1.89e-01	1.00e+00	2.261	1	2	131
GO:0055085	transmembrane transport	1.97e-01	1.00e+00	1.288	2	5	514
GO:0006457	protein folding	2.12e-01	1.00e+00	2.075	1	1	149
GO:0008017	microtubule binding	2.14e-01	1.00e+00	2.065	1	4	150
GO:0042981	regulation of apoptotic process	2.15e-01	1.00e+00	2.056	1	3	151
GO:0046777	protein autophosphorylation	2.24e-01	1.00e+00	1.990	1	3	158
GO:0043005	neuron projection	2.27e-01	1.00e+00	1.963	1	4	161
GO:0005516	calmodulin binding	2.29e-01	1.00e+00	1.954	1	1	162
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.41e-01	1.00e+00	1.092	2	10	589
GO:0000287	magnesium ion binding	2.43e-01	1.00e+00	1.851	1	2	174
GO:0016607	nuclear speck	2.45e-01	1.00e+00	1.843	1	6	175
GO:0031965	nuclear membrane	2.46e-01	1.00e+00	1.835	1	1	176
GO:0034641	cellular nitrogen compound metabolic process	2.47e-01	1.00e+00	1.826	1	3	177
GO:0007049	cell cycle	2.47e-01	1.00e+00	1.826	1	4	177
GO:0005667	transcription factor complex	2.48e-01	1.00e+00	1.818	1	3	178
GO:0031625	ubiquitin protein ligase binding	2.51e-01	1.00e+00	1.802	1	2	180
GO:0005783	endoplasmic reticulum	2.54e-01	1.00e+00	1.041	2	2	610
GO:0006367	transcription initiation from RNA polymerase II promoter	2.55e-01	1.00e+00	1.770	1	5	184
GO:0042803	protein homodimerization activity	2.58e-01	1.00e+00	1.025	2	6	617
GO:0001701	in utero embryonic development	2.86e-01	1.00e+00	1.580	1	2	210
GO:0007067	mitotic nuclear division	3.10e-01	1.00e+00	1.442	1	4	231
GO:0006412	translation	3.14e-01	1.00e+00	1.417	1	5	235
GO:0003713	transcription coactivator activity	3.19e-01	1.00e+00	1.393	1	7	239
GO:0003700	sequence-specific DNA binding transcription factor activity	3.36e-01	1.00e+00	0.747	2	10	748
GO:0004842	ubiquitin-protein transferase activity	3.37e-01	1.00e+00	1.294	1	5	256
GO:0044281	small molecule metabolic process	3.41e-01	1.00e+00	0.540	3	12	1295
GO:0006281	DNA repair	3.46e-01	1.00e+00	1.250	1	4	264
GO:0043065	positive regulation of apoptotic process	3.56e-01	1.00e+00	1.196	1	3	274
GO:0003677	DNA binding	3.66e-01	1.00e+00	0.479	3	16	1351
GO:0019899	enzyme binding	3.71e-01	1.00e+00	1.124	1	3	288
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.73e-01	1.00e+00	0.630	2	13	811
GO:0005743	mitochondrial inner membrane	3.83e-01	1.00e+00	1.065	1	3	300
GO:0004674	protein serine/threonine kinase activity	3.95e-01	1.00e+00	1.009	1	2	312
GO:0019901	protein kinase binding	4.03e-01	1.00e+00	0.972	1	4	320
GO:0008283	cell proliferation	4.13e-01	1.00e+00	0.923	1	3	331
GO:0003682	chromatin binding	4.16e-01	1.00e+00	0.910	1	7	334
GO:0005813	centrosome	4.21e-01	1.00e+00	0.889	1	4	339
GO:0015031	protein transport	4.38e-01	1.00e+00	0.814	1	2	357
GO:0007165	signal transduction	4.52e-01	1.00e+00	0.402	2	8	950
GO:0007155	cell adhesion	4.62e-01	1.00e+00	0.709	1	2	384
GO:0046982	protein heterodimerization activity	4.75e-01	1.00e+00	0.654	1	3	399
GO:0009986	cell surface	4.94e-01	1.00e+00	0.573	1	4	422
GO:0005730	nucleolus	5.11e-01	1.00e+00	0.161	3	28	1684
GO:0055114	oxidation-reduction process	5.41e-01	1.00e+00	0.384	1	2	481
GO:0042802	identical protein binding	5.48e-01	1.00e+00	0.354	1	6	491
GO:0006915	apoptotic process	6.04e-01	1.00e+00	0.137	1	8	571
GO:0005509	calcium ion binding	6.16e-01	1.00e+00	0.092	1	1	589
GO:0005789	endoplasmic reticulum membrane	6.45e-01	1.00e+00	-0.019	1	2	636
GO:0046872	metal ion binding	6.91e-01	1.00e+00	-0.223	2	6	1465
GO:0070062	extracellular vesicular exosome	7.87e-01	1.00e+00	-0.418	3	15	2516
GO:0005887	integral component of plasma membrane	7.94e-01	1.00e+00	-0.614	1	1	961
GO:0005886	plasma membrane	8.54e-01	1.00e+00	-0.590	3	14	2834
GO:0016021	integral component of membrane	9.23e-01	1.00e+00	-0.984	2	7	2483
GO:0006351	transcription, DNA-templated	9.30e-01	1.00e+00	-1.336	1	17	1585

chia-Fav

meta-reg-snw-27130

Interacting subnets

Genes (26)

Interactions (42)

Related GO terms (352)