meta-int-snw-6334

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-3145 chia-screen-data-Fav 2.226 2.10e-07 3.98e-02 3.04e-02 23 17
int-snw-6334 chia-screen-data-Fav 2.813 2.82e-15 6.25e-04 4.06e-03 16 14
reg-snw-8562 chia-screen-data-Fav 2.263 1.35e-07 3.15e-02 2.44e-02 32 24
chia-screen-data-Fav-meta-int-snw-6334 subnetwork

Genes (57)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
ANAPC5 51433 6-1.2642.263239TF--
CNOT1 23019 7-2.3472.263124-Yes-
PHB2 11331 6-2.2362.994151-Yes-
SCN8A 6334 3-1.1732.8135---
PHB 5245 12-2.7432.689163-YesYes
REXO4 57109 3-1.7432.28795TF--
MED28 80306 6-2.4042.44586-Yes-
ICT1 3396 3-2.2102.813208-Yes-
TIA1 7072 4-1.2342.26353TF--
CBLL1 79872 6-1.8972.44538TF--
MED13L 23389 8-2.5502.30750-Yes-
VARS 7407 8-2.3662.689204TFYes-
APC 324 6-2.2933.004384TFYes-
POU5F1 5460 12-5.1483.538179-YesYes
GSTP1 2950 3-2.2512.95559-Yes-
MAPK14 1432 3-1.9022.955304---
FBXO22 26263 8-1.7392.459208TF--
DENR 8562 4-1.0232.26342---
PSMD2 5708 6-4.1723.157389-YesYes
FOXJ3 22887 4-2.4072.36987TFYesYes
EIF2S2 8894 9-2.9992.459103-YesYes
FBXL6 26233 5-2.2532.68922-Yes-
SUV39H2 79723 7-2.3072.41021-YesYes
COPS3 8533 5-1.8732.435118TF--
CASP2 835 4-2.0072.44547TFYes-
ETF1 2107 7-2.8292.50377-YesYes
GTF3C3 9330 4-1.4502.42862TF--
CLPP 8192 3-2.2002.29110-Yes-
CCT7 10574 10-2.3352.459173-Yes-
CPSF3 51692 7-2.6862.50331-YesYes
HNRNPU 3192 12-2.8692.644172-Yes-
ZNRD1 30834 3-1.3752.226106TF--
CLASP1 23332 4-2.3652.45939TFYes-
TMEM14B 81853 3-2.8792.2266-YesYes
NDUFA4L2 56901 10-2.4772.45921-Yes-
CENPA 1058 5-2.1852.393205TFYes-
AGPS 8540 6-2.4242.41027-YesYes
SLC7A5P1 81893 4-3.2172.4454-Yes-
YAP1 10413 12-4.2563.53853-Yes-
NCBP1 4686 8-2.5102.45984-YesYes
SYNCRIP 10492 8-2.4012.503247TFYesYes
SNAP23 8773 3-2.0732.43015-Yes-
ZDHHC20 253832 4-2.6732.32625-Yes-
TADA2B 93624 4-3.0613.08219-Yes-
POLR2E 5434 5-2.0372.644316TFYes-
FTSJ1 24140 5-2.4632.689130-YesYes
EIF2B2 8892 4-2.4622.96895-YesYes
GSPT1 2935 7-2.3132.50347-YesYes
HMBS 3145 3-1.1172.22622---
EIF2B3 8891 5-2.5462.43513-YesYes
COPS6 10980 3-1.7652.393157TF--
GPS1 2873 10-3.6212.68962TFYesYes
NOLC1 9221 5-1.9852.503136TF--
POLH 5429 8-2.5862.45924-YesYes
BTRC 8945 4-1.1442.26364TF--
DDIT3 1649 11-2.8253.504343-YesYes
FUBP1 8880 6-2.4142.38941TFYesYes

Interactions (108)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
CENPA 1058 ZNRD1 30834 pd <> reg.ITFP.txt: no annot
CCT7 10574 REXO4 57109 pd < reg.ITFP.txt: no annot
MAPK14 1432 DDIT3 1649 pp -- int.I2D: BCI, BioGrid, HPRD;
int.HPRD: in vitro
DENR 8562 CBLL1 79872 pd < reg.ITFP.txt: no annot
BTRC 8945 FOXJ3 22887 pd <> reg.ITFP.txt: no annot
ETF1 2107 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
CCT7 10574 ZNRD1 30834 pd < reg.ITFP.txt: no annot
MAPK14 1432 GSTP1 2950 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, BCI
TIA1 7072 CLASP1 23332 pd <> reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
APC 324 CCT7 10574 pp -- int.I2D: Jorgensen_EphR, SOURAV_MAPK_LOW, IntAct
EIF2B2 8892 TADA2B 93624 pp -- int.I2D: BioGrid_Fly, BIND_Fly, FlyLow, IntAct_Fly, MINT_Fly
APC 324 PHB 5245 pp -- int.I2D: Jorgensen_EphR
ETF1 2107 GSPT1 2935 pp -- int.I2D: MINT, BCI, BioGrid, HPRD;
int.Mint: MI:0915(physical association);
int.HPRD: in vivo, yeast 2-hybrid
ICT1 3396 PHB 5245 pp -- int.I2D: BioGrid
POLR2E 5434 ANAPC5 51433 pd <> reg.ITFP.txt: no annot
HNRNPU 3192 ANAPC5 51433 pd < reg.ITFP.txt: no annot
COPS3 8533 COPS6 10980 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BIND, HPRD, IntAct, BCI, INNATEDB, MGI;
int.HPRD: in vitro;
int.DIP: MI:0915(physical association)
PSMD2 5708 CNOT1 23019 pp -- int.I2D: YeastLow
DENR 8562 FBXO22 26263 pd < reg.ITFP.txt: no annot
CNOT1 23019 ANAPC5 51433 pd < reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
POLR2E 5434 MED28 80306 pp -- int.I2D: BioGrid
MAPK14 1432 BTRC 8945 pd < reg.ITFP.txt: no annot
MAPK14 1432 BTRC 8945 pp -- int.I2D: BioGrid
GSPT1 2935 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
GPS1 2873 COPS6 10980 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid, HPRD, MGI;
int.HPRD: in vitro
DENR 8562 ANAPC5 51433 pd < reg.ITFP.txt: no annot
HMBS 3145 COPS3 8533 pd < reg.ITFP.txt: no annot
CENPA 1058 SUV39H2 79723 pd > reg.ITFP.txt: no annot
NCBP1 4686 CBLL1 79872 pd < reg.ITFP.txt: no annot
POLR2E 5434 FTSJ1 24140 pd > reg.ITFP.txt: no annot
CCT7 10574 FBXO22 26263 pd < reg.ITFP.txt: no annot
DENR 8562 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
DENR 8562 GTF3C3 9330 pd < reg.ITFP.txt: no annot
CBLL1 79872 MED28 80306 pd > reg.ITFP.txt: no annot
POLR2E 5434 SNAP23 8773 pd > reg.ITFP.txt: no annot
PHB 5245 PHB2 11331 pp -- int.I2D: BioGrid, BioGrid_Yeast, IntAct_Yeast
VARS 7407 FTSJ1 24140 pd > reg.ITFP.txt: no annot
CENPA 1058 FBXL6 26233 pd > reg.ITFP.txt: no annot
HMBS 3145 REXO4 57109 pd < reg.ITFP.txt: no annot
HMBS 3145 ZNRD1 30834 pd < reg.ITFP.txt: no annot
DDIT3 1649 HNRNPU 3192 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
CENPA 1058 HMBS 3145 pd > reg.ITFP.txt: no annot
HMBS 3145 ANAPC5 51433 pd < reg.ITFP.txt: no annot
PHB2 11331 ZNRD1 30834 pd < reg.ITFP.txt: no annot
HNRNPU 3192 YAP1 10413 pp -- int.I2D: HPRD;
int.HPRD: in vitro, in vivo
HNRNPU 3192 POU5F1 5460 pp -- int.I2D: BioGrid_Mouse, IntAct_Mouse
HNRNPU 3192 BTRC 8945 pp -- int.I2D: BCI, BioGrid, INNATEDB, HPRD;
int.HPRD: in vivo
PSMD2 5708 VARS 7407 pp -- int.I2D: BioGrid_Yeast
BTRC 8945 ZDHHC20 253832 pd > reg.ITFP.txt: no annot
GPS1 2873 CLPP 8192 pd > reg.ITFP.txt: no annot
VARS 7407 FBXL6 26233 pd > reg.ITFP.txt: no annot
MAPK14 1432 EIF2B2 8892 pp -- int.I2D: IntAct, SOURAV_MAPK_LOW
APC 324 FOXJ3 22887 pd <> reg.ITFP.txt: no annot
MAPK14 1432 ANAPC5 51433 pd < reg.ITFP.txt: no annot
DDIT3 1649 VARS 7407 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
MAPK14 1432 FUBP1 8880 pp -- int.I2D: BioGrid
AGPS 8540 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
GPS1 2873 COPS3 8533 pp -- int.Intact: MI:0915(physical association);
int.I2D: HPRD, IntAct, INNATEDB, BioGrid, MGI;
int.HPRD: in vitro, yeast 2-hybrid
MED13L 23389 MED28 80306 pp -- int.I2D: BioGrid
EIF2B3 8891 EIF2S2 8894 pp -- int.I2D: HPRD;
int.HPRD: in vitro
CASP2 835 DENR 8562 pd > reg.ITFP.txt: no annot
ZNRD1 30834 TMEM14B 81853 pd > reg.ITFP.txt: no annot
ETF1 2107 EIF2S2 8894 pp -- int.I2D: BioGrid_Yeast, YeastLow
YAP1 10413 MED28 80306 pp -- int.I2D: MINT;
int.Mint: MI:0915(physical association)
PHB 5245 ZNRD1 30834 pd < reg.ITFP.txt: no annot
BTRC 8945 CNOT1 23019 pd > reg.ITFP.txt: no annot
PSMD2 5708 CCT7 10574 pp -- int.I2D: BioGrid_Yeast
PHB2 11331 FTSJ1 24140 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
COPS3 8533 EIF2B3 8891 pd > reg.ITFP.txt: no annot
HMBS 3145 COPS6 10980 pd < reg.ITFP.txt: no annot
MAPK14 1432 POLR2E 5434 pd < reg.ITFP.txt: no annot
DENR 8562 NOLC1 9221 pd < reg.ITFP.txt: no annot
EIF2B2 8892 EIF2S2 8894 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh
SYNCRIP 10492 CPSF3 51692 pd > reg.ITFP.txt: no annot
EIF2S2 8894 GTF3C3 9330 pd < reg.ITFP.txt: no annot
SYNCRIP 10492 SUV39H2 79723 pd > reg.ITFP.txt: no annot
MED13L 23389 ANAPC5 51433 pd < reg.ITFP.txt: no annot
CENPA 1058 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
PSMD2 5708 EIF2B2 8892 pp -- int.I2D: IntAct_Yeast
TIA1 7072 DENR 8562 pd > reg.ITFP.txt: no annot
DDIT3 1649 GSTP1 2950 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
CASP2 835 SLC7A5P1 81893 pd > reg.ITFP.txt: no annot
GPS1 2873 PHB2 11331 pd > reg.ITFP.txt: no annot
COPS6 10980 FBXO22 26263 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, IntAct
CASP2 835 CBLL1 79872 pd <> reg.ITFP.txt: no annot
SNAP23 8773 ANAPC5 51433 pd < reg.ITFP.txt: no annot
NOLC1 9221 FTSJ1 24140 pd > reg.ITFP.txt: no annot
APC 324 BTRC 8945 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, IntAct, INNATEDB
GSPT1 2935 NOLC1 9221 pd < reg.ITFP.txt: no annot
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
HNRNPU 3192 SYNCRIP 10492 pp -- int.Mint: MI:0915(physical association)
MAPK14 1432 SCN8A 6334 pp -- int.I2D: HPRD;
int.HPRD: in vivo
ICT1 3396 PHB2 11331 pp -- int.I2D: BioGrid
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
PHB 5245 SCN8A 6334 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
APC 324 SYNCRIP 10492 pp -- int.I2D: Jorgensen_EphR
HNRNPU 3192 POLR2E 5434 pd < reg.ITFP.txt: no annot
POLR2E 5434 VARS 7407 pd <> reg.ITFP.txt: no annot
FUBP1 8880 ANAPC5 51433 pd <> reg.ITFP.txt: no annot
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
CLPP 8192 COPS6 10980 pd < reg.ITFP.txt: no annot
DENR 8562 BTRC 8945 pd < reg.ITFP.txt: no annot
BTRC 8945 YAP1 10413 pp -- int.I2D: BioGrid, MINT;
int.Mint: MI:0915(physical association)
PSMD2 5708 PHB2 11331 pp -- int.I2D: IntAct_Yeast

Related GO terms (610)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0010467gene expression4.96e-088.09e-042.5831427669
GO:0005515protein binding2.15e-063.52e-020.86639776127
GO:0010388cullin deneddylation3.34e-065.46e-026.577359
GO:0005654nucleoplasm3.47e-065.67e-021.97215311095
GO:0005829cytosol2.40e-053.91e-011.29822382562
GO:0003743translation initiation factor activity2.52e-054.11e-014.5474549
GO:0051716cellular response to stimulus7.16e-051.00e+007.162224
GO:0003747translation release factor activity7.16e-051.00e+007.162224
GO:0070934CRD-mediated mRNA stabilization1.19e-041.00e+006.840225
GO:0070937CRD-mediated mRNA stability complex1.78e-041.00e+006.577226
GO:0005851eukaryotic translation initiation factor 2B complex1.78e-041.00e+006.577236
GO:0008180COP9 signalosome2.24e-041.00e+004.6593634
GO:0000398mRNA splicing, via spliceosome2.72e-041.00e+003.11759165
GO:0044822poly(A) RNA binding2.87e-041.00e+001.67212271078
GO:0006379mRNA cleavage5.30e-041.00e+005.8402210
GO:0033147negative regulation of intracellular estrogen receptor signaling pathway5.30e-041.00e+005.8402210
GO:0051010microtubule plus-end binding6.46e-041.00e+005.7022211
GO:0001054RNA polymerase I activity6.46e-041.00e+005.7022211
GO:0030529ribonucleoprotein complex6.71e-041.00e+003.32946114
GO:0005736DNA-directed RNA polymerase I complex7.73e-041.00e+005.5772212
GO:0008143poly(A) binding7.73e-041.00e+005.5772212
GO:0005739mitochondrion8.59e-041.00e+001.59011161046
GO:0042789mRNA transcription from RNA polymerase II promoter9.12e-041.00e+005.4612213
GO:0043409negative regulation of MAPK cascade9.12e-041.00e+005.4612213
GO:0016071mRNA metabolic process1.07e-031.00e+002.68358223
GO:0006479protein methylation1.22e-031.00e+005.2552215
GO:0008380RNA splicing1.28e-031.00e+002.625514232
GO:0007026negative regulation of microtubule depolymerization1.39e-031.00e+005.1622216
GO:0003723RNA binding1.45e-031.00e+002.275615355
GO:0016070RNA metabolic process1.68e-031.00e+002.53558247
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.87e-031.00e+003.6173470
GO:0014003oligodendrocyte development2.19e-031.00e+004.8402320
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.20e-031.00e+003.5373474
GO:0016032viral process2.63e-031.00e+001.892716540
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process2.65e-031.00e+003.4433479
GO:0044212transcription regulatory region DNA binding2.98e-031.00e+002.74445171
GO:0008135translation factor activity, nucleic acid binding3.15e-031.00e+004.5772224
GO:0070126mitochondrial translational termination3.49e-031.00e+008.162111
GO:0002128tRNA nucleoside ribose methylation3.49e-031.00e+008.162111
GO:2000016negative regulation of determination of dorsal identity3.49e-031.00e+008.162111
GO:0097057TRAF2-GSTP1 complex3.49e-031.00e+008.162111
GO:0042483negative regulation of odontogenesis3.49e-031.00e+008.162111
GO:0060795cell fate commitment involved in formation of primary germ layer3.49e-031.00e+008.162111
GO:0031592centrosomal corona3.49e-031.00e+008.162111
GO:0097165nuclear stress granule3.49e-031.00e+008.162111
GO:0016150translation release factor activity, codon nonspecific3.49e-031.00e+008.162111
GO:0051171regulation of nitrogen compound metabolic process3.49e-031.00e+008.162111
GO:0014835myoblast differentiation involved in skeletal muscle regeneration3.49e-031.00e+008.162111
GO:0008079translation termination factor activity3.49e-031.00e+008.162111
GO:0004418hydroxymethylbilane synthase activity3.49e-031.00e+008.162111
GO:0070664negative regulation of leukocyte proliferation3.49e-031.00e+008.162111
GO:0035732nitric oxide storage3.49e-031.00e+008.162111
GO:0008609alkylglycerone-phosphate synthase activity3.49e-031.00e+008.162111
GO:0090308regulation of methylation-dependent chromatin silencing3.49e-031.00e+008.162111
GO:0090081regulation of heart induction by regulation of canonical Wnt signaling pathway3.49e-031.00e+008.162111
GO:0070026nitric oxide binding3.49e-031.00e+008.162111
GO:0035731dinitrosyl-iron complex binding3.49e-031.00e+008.162111
GO:0018160peptidyl-pyrromethane cofactor linkage3.49e-031.00e+008.162111
GO:0038066p38MAPK cascade3.49e-031.00e+008.162111
GO:0035730S-nitrosoglutathione binding3.49e-031.00e+008.162111
GO:0006366transcription from RNA polymerase II promoter3.56e-031.00e+002.015614425
GO:0090090negative regulation of canonical Wnt signaling pathway3.59e-031.00e+003.2873488
GO:0031047gene silencing by RNA3.69e-031.00e+004.4612226
GO:0030331estrogen receptor binding3.98e-031.00e+004.4072227
GO:0001649osteoblast differentiation4.45e-031.00e+003.1773395
GO:00063707-methylguanosine mRNA capping4.90e-031.00e+004.2552230
GO:0007094mitotic spindle assembly checkpoint5.22e-031.00e+004.2072331
GO:0016592mediator complex6.62e-031.00e+004.0322535
GO:0060242contact inhibition6.97e-031.00e+007.162112
GO:0000939condensed chromosome inner kinetochore6.97e-031.00e+007.162112
GO:0045309protein phosphorylated amino acid binding6.97e-031.00e+007.162112
GO:0060965negative regulation of gene silencing by miRNA6.97e-031.00e+007.162112
GO:0030981cortical microtubule cytoskeleton6.97e-031.00e+007.162112
GO:0044324regulation of transcription involved in anterior/posterior axis specification6.97e-031.00e+007.162112
GO:0004832valine-tRNA ligase activity6.97e-031.00e+007.162112
GO:0009368endopeptidase Clp complex6.97e-031.00e+007.162112
GO:0009890negative regulation of biosynthetic process6.97e-031.00e+007.162112
GO:0044337canonical Wnt signaling pathway involved in positive regulation of apoptotic process6.97e-031.00e+007.162112
GO:0008175tRNA methyltransferase activity6.97e-031.00e+007.162112
GO:0005846nuclear cap binding complex6.97e-031.00e+007.162112
GO:0002176male germ cell proliferation6.97e-031.00e+007.162112
GO:0006438valyl-tRNA aminoacylation6.97e-031.00e+007.162112
GO:0009786regulation of asymmetric cell division6.97e-031.00e+007.162112
GO:0019207kinase regulator activity6.97e-031.00e+007.162112
GO:0001554luteolysis6.97e-031.00e+007.162112
GO:1990440positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress6.97e-031.00e+007.162112
GO:0031111negative regulation of microtubule polymerization or depolymerization6.97e-031.00e+007.162112
GO:0051294establishment of spindle orientation6.97e-031.00e+007.162112
GO:0009798axis specification6.97e-031.00e+007.162112
GO:0006446regulation of translational initiation7.00e-031.00e+003.9922236
GO:0042552myelination7.00e-031.00e+003.9922236
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay7.38e-031.00e+002.91433114
GO:0044267cellular protein metabolic process7.41e-031.00e+001.79567495
GO:0000209protein polyubiquitination7.75e-031.00e+002.88935116
GO:0006383transcription from RNA polymerase III promoter8.17e-031.00e+003.8762339
GO:0009408response to heat8.58e-031.00e+003.8402240
GO:0035019somatic stem cell maintenance8.58e-031.00e+003.8402240
GO:0005881cytoplasmic microtubule9.00e-031.00e+003.8042241
GO:0017148negative regulation of translation9.00e-031.00e+003.8042341
GO:0006412translation9.12e-031.00e+002.28545235
GO:0031124mRNA 3'-end processing9.43e-031.00e+003.7692442
GO:0050434positive regulation of viral transcription1.03e-021.00e+003.7022244
GO:0071638negative regulation of monocyte chemotactic protein-1 production1.04e-021.00e+006.577113
GO:0071459protein localization to chromosome, centromeric region1.04e-021.00e+006.577113
GO:0016149translation release factor activity, codon specific1.04e-021.00e+006.577113
GO:0004045aminoacyl-tRNA hydrolase activity1.04e-021.00e+006.577113
GO:0036123histone H3-K9 dimethylation1.04e-021.00e+006.577113
GO:0035726common myeloid progenitor cell proliferation1.04e-021.00e+006.577113
GO:0005850eukaryotic translation initiation factor 2 complex1.04e-021.00e+006.577123
GO:0090400stress-induced premature senescence1.04e-021.00e+006.577113
GO:0003130BMP signaling pathway involved in heart induction1.04e-021.00e+006.577113
GO:0006369termination of RNA polymerase II transcription1.08e-021.00e+003.6702445
GO:0006413translational initiation1.08e-021.00e+002.71334131
GO:0043525positive regulation of neuron apoptotic process1.12e-021.00e+003.6382246
GO:0043434response to peptide hormone1.12e-021.00e+003.6382246
GO:0048511rhythmic process1.17e-021.00e+003.6072247
GO:0004842ubiquitin-protein transferase activity1.22e-021.00e+002.16245256
GO:0000278mitotic cell cycle1.25e-021.00e+001.847512398
GO:0005778peroxisomal membrane1.32e-021.00e+003.5182250
GO:0000778condensed nuclear chromosome kinetochore1.39e-021.00e+006.162114
GO:0042036negative regulation of cytokine biosynthetic process1.39e-021.00e+006.162114
GO:0097452GAIT complex1.39e-021.00e+006.162124
GO:0060913cardiac cell fate determination1.39e-021.00e+006.162114
GO:0007000nucleolus organization1.39e-021.00e+006.162114
GO:0051771negative regulation of nitric-oxide synthase biosynthetic process1.39e-021.00e+006.162114
GO:0046523S-methyl-5-thioribose-1-phosphate isomerase activity1.39e-021.00e+006.162114
GO:0019887protein kinase regulator activity1.39e-021.00e+006.162114
GO:0008611ether lipid biosynthetic process1.39e-021.00e+006.162114
GO:0051151negative regulation of smooth muscle cell differentiation1.39e-021.00e+006.162114
GO:0006290pyrimidine dimer repair1.39e-021.00e+006.162114
GO:0043515kinetochore binding1.39e-021.00e+006.162114
GO:0002192IRES-dependent translational initiation1.39e-021.00e+006.162114
GO:0000775chromosome, centromeric region1.42e-021.00e+003.4612352
GO:0045892negative regulation of transcription, DNA-templated1.60e-021.00e+001.75657424
GO:0070461SAGA-type complex1.73e-021.00e+005.840125
GO:0044336canonical Wnt signaling pathway involved in negative regulation of apoptotic process1.73e-021.00e+005.840115
GO:0048742regulation of skeletal muscle fiber development1.73e-021.00e+005.840115
GO:0045292mRNA cis splicing, via spliceosome1.73e-021.00e+005.840115
GO:0001714endodermal cell fate specification1.73e-021.00e+005.840115
GO:0003407neural retina development1.73e-021.00e+005.840115
GO:0097153cysteine-type endopeptidase activity involved in apoptotic process1.73e-021.00e+005.840115
GO:0005828kinetochore microtubule1.73e-021.00e+005.840115
GO:0043620regulation of DNA-templated transcription in response to stress1.73e-021.00e+005.840115
GO:0010606positive regulation of cytoplasmic mRNA processing body assembly1.73e-021.00e+005.840115
GO:0031023microtubule organizing center organization1.73e-021.00e+005.840115
GO:0006398histone mRNA 3'-end processing1.73e-021.00e+005.840115
GO:0051525NFAT protein binding1.73e-021.00e+005.840115
GO:0031442positive regulation of mRNA 3'-end processing1.73e-021.00e+005.840115
GO:0033600negative regulation of mammary gland epithelial cell proliferation1.73e-021.00e+005.840115
GO:0006449regulation of translational termination1.73e-021.00e+005.840115
GO:1901741positive regulation of myoblast fusion1.73e-021.00e+005.840115
GO:0032057negative regulation of translational initiation in response to stress1.73e-021.00e+005.840115
GO:0036124histone H3-K9 trimethylation1.73e-021.00e+005.840115
GO:0006974cellular response to DNA damage stimulus1.78e-021.00e+002.44334158
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity1.81e-021.00e+003.2792259
GO:0006396RNA processing1.86e-021.00e+003.2552460
GO:0008013beta-catenin binding1.86e-021.00e+003.2552460
GO:0006406mRNA export from nucleus1.98e-021.00e+003.2072562
GO:0000776kinetochore2.04e-021.00e+003.1842463
GO:0030858positive regulation of epithelial cell differentiation2.08e-021.00e+005.577116
GO:0042797tRNA transcription from RNA polymerase III promoter2.08e-021.00e+005.577126
GO:0050847progesterone receptor signaling pathway2.08e-021.00e+005.577116
GO:0046974histone methyltransferase activity (H3-K9 specific)2.08e-021.00e+005.577116
GO:0032873negative regulation of stress-activated MAPK cascade2.08e-021.00e+005.577116
GO:0032691negative regulation of interleukin-1 beta production2.08e-021.00e+005.577116
GO:00427915S class rRNA transcription from RNA polymerase III type 1 promoter2.08e-021.00e+005.577126
GO:0006333chromatin assembly or disassembly2.08e-021.00e+005.577116
GO:0060762regulation of branching involved in mammary gland duct morphogenesis2.08e-021.00e+005.577116
GO:0008762UDP-N-acetylmuramate dehydrogenase activity2.08e-021.00e+005.577116
GO:0002181cytoplasmic translation2.08e-021.00e+005.577116
GO:0060744mammary gland branching involved in thelarche2.08e-021.00e+005.577116
GO:0048024regulation of mRNA splicing, via spliceosome2.08e-021.00e+005.577116
GO:2000323negative regulation of glucocorticoid receptor signaling pathway2.08e-021.00e+005.577116
GO:0000127transcription factor TFIIIC complex2.08e-021.00e+005.577126
GO:0008432JUN kinase binding2.08e-021.00e+005.577116
GO:0071204histone pre-mRNA 3'end processing complex2.08e-021.00e+005.577116
GO:0009749response to glucose2.10e-021.00e+003.1622264
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest2.17e-021.00e+003.1392365
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.17e-021.00e+003.1392365
GO:0006368transcription elongation from RNA polymerase II promoter2.29e-021.00e+003.0952367
GO:0032930positive regulation of superoxide anion generation2.42e-021.00e+005.354117
GO:0042753positive regulation of circadian rhythm2.42e-021.00e+005.354117
GO:0004521endoribonuclease activity2.42e-021.00e+005.354117
GO:0010458exit from mitosis2.42e-021.00e+005.354117
GO:0002674negative regulation of acute inflammatory response2.42e-021.00e+005.354117
GO:0007091metaphase/anaphase transition of mitotic cell cycle2.42e-021.00e+005.354117
GO:0060770negative regulation of epithelial cell proliferation involved in prostate gland development2.42e-021.00e+005.354117
GO:0051988regulation of attachment of spindle microtubules to kinetochore2.42e-021.00e+005.354117
GO:0032790ribosome disassembly2.42e-021.00e+005.354117
GO:0002161aminoacyl-tRNA editing activity2.42e-021.00e+005.354117
GO:0006301postreplication repair2.42e-021.00e+005.354117
GO:0006282regulation of DNA repair2.42e-021.00e+005.354117
GO:0035234ectopic germ cell programmed cell death2.42e-021.00e+005.354117
GO:0032872regulation of stress-activated MAPK cascade2.76e-021.00e+005.162118
GO:0042582azurophil granule2.76e-021.00e+005.162118
GO:0045670regulation of osteoclast differentiation2.76e-021.00e+005.162118
GO:0042754negative regulation of circadian rhythm2.76e-021.00e+005.162118
GO:0001955blood vessel maturation2.76e-021.00e+005.162118
GO:0006903vesicle targeting2.76e-021.00e+005.162118
GO:0000780condensed nuclear chromosome, centromeric region2.76e-021.00e+005.162118
GO:0005085guanyl-nucleotide exchange factor activity2.76e-021.00e+002.9522274
GO:0001055RNA polymerase II activity2.76e-021.00e+005.162118
GO:0000339RNA cap binding2.76e-021.00e+005.162118
GO:0010831positive regulation of myotube differentiation2.76e-021.00e+005.162118
GO:0016779nucleotidyltransferase activity2.76e-021.00e+005.162118
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process2.90e-021.00e+002.9142276
GO:0005634nucleus2.95e-021.00e+000.50924554828
GO:0010804negative regulation of tumor necrosis factor-mediated signaling pathway3.10e-021.00e+004.992119
GO:00084095'-3' exonuclease activity3.10e-021.00e+004.992119
GO:0005847mRNA cleavage and polyadenylation specificity factor complex3.10e-021.00e+004.992119
GO:0033598mammary gland epithelial cell proliferation3.10e-021.00e+004.992119
GO:0000302response to reactive oxygen species3.10e-021.00e+004.992119
GO:0019509L-methionine biosynthetic process from methylthioadenosine3.10e-021.00e+004.992119
GO:0006983ER overload response3.10e-021.00e+004.992119
GO:0071354cellular response to interleukin-63.10e-021.00e+004.992119
GO:0006782protoporphyrinogen IX biosynthetic process3.10e-021.00e+004.992119
GO:0005832chaperonin-containing T-complex3.10e-021.00e+004.992119
GO:0032495response to muramyl dipeptide3.10e-021.00e+004.992129
GO:0071013catalytic step 2 spliceosome3.11e-021.00e+002.8582379
GO:0071222cellular response to lipopolysaccharide3.26e-021.00e+002.8222281
GO:0002199zona pellucida receptor complex3.44e-021.00e+004.8401110
GO:0045667regulation of osteoblast differentiation3.44e-021.00e+004.8401110
GO:0001518voltage-gated sodium channel complex3.44e-021.00e+004.8401110
GO:0010225response to UV-C3.44e-021.00e+004.8401210
GO:0008610lipid biosynthetic process3.44e-021.00e+004.8401110
GO:0043194axon initial segment3.44e-021.00e+004.8401110
GO:0031274positive regulation of pseudopodium assembly3.44e-021.00e+004.8401110
GO:0006450regulation of translational fidelity3.44e-021.00e+004.8401110
GO:0071949FAD binding3.44e-021.00e+004.8401110
GO:1900153positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay3.44e-021.00e+004.8401110
GO:0051382kinetochore assembly3.44e-021.00e+004.8401110
GO:0000731DNA synthesis involved in DNA repair3.44e-021.00e+004.8401110
GO:0010944negative regulation of transcription by competitive promoter binding3.44e-021.00e+004.8401110
GO:0030877beta-catenin destruction complex3.44e-021.00e+004.8401110
GO:0006355regulation of transcription, DNA-templated3.70e-021.00e+001.0538131104
GO:0006415translational termination3.71e-021.00e+002.7192287
GO:0048387negative regulation of retinoic acid receptor signaling pathway3.78e-021.00e+004.7021111
GO:0031116positive regulation of microtubule polymerization3.78e-021.00e+004.7021111
GO:0004535poly(A)-specific ribonuclease activity3.78e-021.00e+004.7021111
GO:2000036regulation of stem cell maintenance3.78e-021.00e+004.7021111
GO:0060391positive regulation of SMAD protein import into nucleus3.78e-021.00e+004.7021111
GO:0043122regulation of I-kappaB kinase/NF-kappaB signaling3.78e-021.00e+004.7021111
GO:0005845mRNA cap binding complex3.78e-021.00e+004.7021111
GO:0045663positive regulation of myoblast differentiation3.78e-021.00e+004.7021111
GO:0045662negative regulation of myoblast differentiation3.78e-021.00e+004.7021111
GO:0019395fatty acid oxidation3.78e-021.00e+004.7021111
GO:0004707MAP kinase activity3.78e-021.00e+004.7021111
GO:0060213positive regulation of nuclear-transcribed mRNA poly(A) tail shortening3.78e-021.00e+004.7021111
GO:0035413positive regulation of catenin import into nucleus3.78e-021.00e+004.7021111
GO:0007178transmembrane receptor protein serine/threonine kinase signaling pathway3.78e-021.00e+004.7021111
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process3.78e-021.00e+004.7021111
GO:0042770signal transduction in response to DNA damage3.78e-021.00e+004.7021111
GO:0034453microtubule anchoring4.11e-021.00e+004.5771112
GO:0061136regulation of proteasomal protein catabolic process4.11e-021.00e+004.5771112
GO:00709353'-UTR-mediated mRNA stabilization4.11e-021.00e+004.5771112
GO:0051146striated muscle cell differentiation4.11e-021.00e+004.5771112
GO:0045295gamma-catenin binding4.11e-021.00e+004.5771112
GO:0005838proteasome regulatory particle4.11e-021.00e+004.5771112
GO:0042581specific granule4.11e-021.00e+004.5771112
GO:0032886regulation of microtubule-based process4.11e-021.00e+004.5771112
GO:0008334histone mRNA metabolic process4.11e-021.00e+004.5771112
GO:0043281regulation of cysteine-type endopeptidase activity involved in apoptotic process4.11e-021.00e+004.5771112
GO:0007140male meiosis4.45e-021.00e+004.4611113
GO:0043508negative regulation of JUN kinase activity4.45e-021.00e+004.4611113
GO:0009416response to light stimulus4.45e-021.00e+004.4611113
GO:0030914STAGA complex4.45e-021.00e+004.4611113
GO:0042974retinoic acid receptor binding4.45e-021.00e+004.4611113
GO:0004708MAP kinase kinase activity4.45e-021.00e+004.4611113
GO:0060766negative regulation of androgen receptor signaling pathway4.45e-021.00e+004.4611113
GO:0044295axonal growth cone4.45e-021.00e+004.4611113
GO:0030234enzyme regulator activity4.45e-021.00e+004.4611113
GO:0060444branching involved in mammary gland duct morphogenesis4.45e-021.00e+004.4611113
GO:0035198miRNA binding4.45e-021.00e+004.4611113
GO:0030018Z disc4.60e-021.00e+002.5472298
GO:0035371microtubule plus-end4.78e-021.00e+004.3541114
GO:0050905neuromuscular process4.78e-021.00e+004.3541114
GO:0071480cellular response to gamma radiation4.78e-021.00e+004.3541114
GO:0004527exonuclease activity4.78e-021.00e+004.3541114
GO:0007020microtubule nucleation4.78e-021.00e+004.3541114
GO:0005095GTPase inhibitor activity4.78e-021.00e+004.3541114
GO:0045807positive regulation of endocytosis4.78e-021.00e+004.3541114
GO:0006915apoptotic process4.86e-021.00e+001.32658571
GO:0007417central nervous system development4.86e-021.00e+002.50322101
GO:0017091AU-rich element binding5.11e-021.00e+004.2551215
GO:0001824blastocyst development5.11e-021.00e+004.2551115
GO:0030014CCR4-NOT complex5.11e-021.00e+004.2551115
GO:0060749mammary gland alveolus development5.11e-021.00e+004.2551115
GO:0042307positive regulation of protein import into nucleus5.11e-021.00e+004.2551215
GO:0005762mitochondrial large ribosomal subunit5.11e-021.00e+004.2551115
GO:0033268node of Ranvier5.45e-021.00e+004.1621116
GO:0000132establishment of mitotic spindle orientation5.45e-021.00e+004.1621116
GO:0001056RNA polymerase III activity5.45e-021.00e+004.1621116
GO:0042176regulation of protein catabolic process5.45e-021.00e+004.1621116
GO:0005665DNA-directed RNA polymerase II, core complex5.45e-021.00e+004.1621116
GO:0051603proteolysis involved in cellular protein catabolic process5.45e-021.00e+004.1621116
GO:0046716muscle cell cellular homeostasis5.45e-021.00e+004.1621116
GO:0051276chromosome organization5.45e-021.00e+004.1621216
GO:0005248voltage-gated sodium channel activity5.45e-021.00e+004.1621116
GO:0016409palmitoyltransferase activity5.78e-021.00e+004.0741117
GO:0043536positive regulation of blood vessel endothelial cell migration5.78e-021.00e+004.0741117
GO:0022624proteasome accessory complex5.78e-021.00e+004.0741117
GO:0001829trophectodermal cell differentiation5.78e-021.00e+004.0741217
GO:0005666DNA-directed RNA polymerase III complex5.78e-021.00e+004.0741117
GO:0070372regulation of ERK1 and ERK2 cascade5.78e-021.00e+004.0741117
GO:0001731formation of translation preinitiation complex5.78e-021.00e+004.0741117
GO:0031122cytoplasmic microtubule organization6.11e-021.00e+003.9921118
GO:0006778porphyrin-containing compound metabolic process6.11e-021.00e+003.9921218
GO:0006386termination of RNA polymerase III transcription6.11e-021.00e+003.9921118
GO:0019228neuronal action potential6.11e-021.00e+003.9921118
GO:0006385transcription elongation from RNA polymerase III promoter6.11e-021.00e+003.9921118
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process6.43e-021.00e+003.9141119
GO:0045736negative regulation of cyclin-dependent protein serine/threonine kinase activity6.43e-021.00e+003.9141219
GO:0051090regulation of sequence-specific DNA binding transcription factor activity6.76e-021.00e+003.8401120
GO:0018345protein palmitoylation6.76e-021.00e+003.8401120
GO:0006783heme biosynthetic process6.76e-021.00e+003.8401120
GO:0001578microtubule bundle formation6.76e-021.00e+003.8401120
GO:0001502cartilage condensation6.76e-021.00e+003.8401120
GO:0035924cellular response to vascular endothelial growth factor stimulus6.76e-021.00e+003.8401120
GO:0097194execution phase of apoptosis6.76e-021.00e+003.8401120
GO:0005680anaphase-promoting complex6.76e-021.00e+003.8401120
GO:0048010vascular endothelial growth factor receptor signaling pathway7.09e-021.00e+003.7691121
GO:0045648positive regulation of erythrocyte differentiation7.09e-021.00e+003.7691121
GO:0045862positive regulation of proteolysis7.09e-021.00e+003.7691221
GO:0004364glutathione transferase activity7.09e-021.00e+003.7691121
GO:0016575histone deacetylation7.09e-021.00e+003.7691121
GO:0032757positive regulation of interleukin-8 production7.09e-021.00e+003.7691121
GO:0031648protein destabilization7.09e-021.00e+003.7691221
GO:0009954proximal/distal pattern formation7.09e-021.00e+003.7691121
GO:0000281mitotic cytokinesis7.09e-021.00e+003.7691121
GO:0007050cell cycle arrest7.17e-021.00e+002.18423126
GO:0006511ubiquitin-dependent protein catabolic process7.27e-021.00e+002.17323127
GO:0030316osteoclast differentiation7.41e-021.00e+003.7021122
GO:0005720nuclear heterochromatin7.41e-021.00e+003.7021122
GO:0006378mRNA polyadenylation7.41e-021.00e+003.7021222
GO:0036464cytoplasmic ribonucleoprotein granule7.41e-021.00e+003.7021122
GO:0001205RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription7.41e-021.00e+003.7021222
GO:0030335positive regulation of cell migration7.57e-021.00e+002.13922130
GO:0034660ncRNA metabolic process7.74e-021.00e+003.6381123
GO:0045879negative regulation of smoothened signaling pathway7.74e-021.00e+003.6381123
GO:0071346cellular response to interferon-gamma7.74e-021.00e+003.6381223
GO:1901687glutathione derivative biosynthetic process7.74e-021.00e+003.6381123
GO:0019706protein-cysteine S-palmitoyltransferase activity7.74e-021.00e+003.6381123
GO:0016020membrane7.86e-021.00e+000.71410271746
GO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress8.06e-021.00e+003.5771124
GO:0007163establishment or maintenance of cell polarity8.06e-021.00e+003.5771124
GO:0048147negative regulation of fibroblast proliferation8.06e-021.00e+003.5771124
GO:0006363termination of RNA polymerase I transcription8.06e-021.00e+003.5771124
GO:2000379positive regulation of reactive oxygen species metabolic process8.06e-021.00e+003.5771124
GO:0000086G2/M transition of mitotic cell cycle8.28e-021.00e+002.06423137
GO:0000289nuclear-transcribed mRNA poly(A) tail shortening8.38e-021.00e+003.5181125
GO:0071479cellular response to ionizing radiation8.38e-021.00e+003.5181125
GO:0086010membrane depolarization during action potential8.38e-021.00e+003.5181125
GO:0030864cortical actin cytoskeleton8.38e-021.00e+003.5181125
GO:0003899DNA-directed RNA polymerase activity8.38e-021.00e+003.5181125
GO:0045296cadherin binding8.38e-021.00e+003.5181125
GO:0016567protein ubiquitination8.66e-021.00e+001.52335299
GO:0070979protein K11-linked ubiquitination8.70e-021.00e+003.4611126
GO:0090503RNA phosphodiester bond hydrolysis, exonucleolytic8.70e-021.00e+003.4611126
GO:0016055Wnt signaling pathway8.70e-021.00e+002.02223141
GO:0035329hippo signaling8.70e-021.00e+003.4611126
GO:0061025membrane fusion8.70e-021.00e+003.4611126
GO:0051209release of sequestered calcium ion into cytosol8.70e-021.00e+003.4611226
GO:0051149positive regulation of muscle cell differentiation9.02e-021.00e+003.4071127
GO:0032720negative regulation of tumor necrosis factor production9.02e-021.00e+003.4071227
GO:0000387spliceosomal snRNP assembly9.02e-021.00e+003.4071127
GO:0007422peripheral nervous system development9.02e-021.00e+003.4071127
GO:0006913nucleocytoplasmic transport9.02e-021.00e+003.4071127
GO:0000188inactivation of MAPK activity9.02e-021.00e+003.4071127
GO:0034080CENP-A containing nucleosome assembly9.02e-021.00e+003.4071227
GO:0007339binding of sperm to zona pellucida9.02e-021.00e+003.4071127
GO:0000077DNA damage checkpoint9.34e-021.00e+003.3541128
GO:0000976transcription regulatory region sequence-specific DNA binding9.34e-021.00e+003.3541128
GO:0043022ribosome binding9.34e-021.00e+003.3541228
GO:2001235positive regulation of apoptotic signaling pathway9.34e-021.00e+003.3541128
GO:0008017microtubule binding9.66e-021.00e+001.93324150
GO:0019005SCF ubiquitin ligase complex9.66e-021.00e+003.3041129
GO:0007628adult walking behavior9.66e-021.00e+003.3041129
GO:0071897DNA biosynthetic process9.66e-021.00e+003.3041129
GO:0005913cell-cell adherens junction9.66e-021.00e+003.3041129
GO:0016485protein processing9.66e-021.00e+003.3041129
GO:0006749glutathione metabolic process9.66e-021.00e+003.3041129
GO:0003887DNA-directed DNA polymerase activity9.66e-021.00e+003.3041129
GO:0031663lipopolysaccharide-mediated signaling pathway9.66e-021.00e+003.3041129
GO:0000082G1/S transition of mitotic cell cycle9.66e-021.00e+001.93324150
GO:0042981regulation of apoptotic process9.77e-021.00e+001.92323151
GO:0006360transcription from RNA polymerase I promoter9.97e-021.00e+003.2551130
GO:0043124negative regulation of I-kappaB kinase/NF-kappaB signaling9.97e-021.00e+003.2551130
GO:0010494cytoplasmic stress granule9.97e-021.00e+003.2551230
GO:0070373negative regulation of ERK1 and ERK2 cascade1.03e-011.00e+003.2071131
GO:0005782peroxisomal matrix1.03e-011.00e+003.2071131
GO:0006139nucleobase-containing compound metabolic process1.06e-011.00e+003.1621132
GO:0042594response to starvation1.06e-011.00e+003.1621332
GO:0002062chondrocyte differentiation1.06e-011.00e+003.1621232
GO:1903507negative regulation of nucleic acid-templated transcription1.06e-011.00e+003.1621132
GO:0009953dorsal/ventral pattern formation1.06e-011.00e+003.1621132
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic1.06e-011.00e+003.1621132
GO:0005525GTP binding1.07e-011.00e+001.38935328
GO:0007162negative regulation of cell adhesion1.09e-011.00e+003.1171133
GO:0070830tight junction assembly1.09e-011.00e+003.1171133
GO:0033077T cell differentiation in thymus1.09e-011.00e+003.1171133
GO:0001104RNA polymerase II transcription cofactor activity1.09e-011.00e+003.1171333
GO:0003682chromatin binding1.11e-011.00e+001.36337334
GO:0043407negative regulation of MAP kinase activity1.12e-011.00e+003.0741134
GO:0042692muscle cell differentiation1.12e-011.00e+003.0741134
GO:0005876spindle microtubule1.12e-011.00e+003.0741134
GO:2001237negative regulation of extrinsic apoptotic signaling pathway1.15e-011.00e+003.0321135
GO:0097192extrinsic apoptotic signaling pathway in absence of ligand1.15e-011.00e+003.0321135
GO:0001942hair follicle development1.15e-011.00e+003.0321135
GO:0048538thymus development1.18e-011.00e+002.9921136
GO:0009267cellular response to starvation1.18e-011.00e+002.9921136
GO:0003700sequence-specific DNA binding transcription factor activity1.19e-011.00e+000.937510748
GO:0051084'de novo' posttranslational protein folding1.22e-011.00e+002.9521137
GO:0001541ovarian follicle development1.22e-011.00e+002.9521137
GO:0042752regulation of circadian rhythm1.22e-011.00e+002.9521337
GO:0007049cell cycle1.27e-011.00e+001.69424177
GO:0051781positive regulation of cell division1.28e-011.00e+002.8761139
GO:0071407cellular response to organic cyclic compound1.28e-011.00e+002.8761339
GO:0003714transcription corepressor activity1.29e-011.00e+001.67825179
GO:0005737cytoplasm1.33e-011.00e+000.37418433976
GO:0045785positive regulation of cell adhesion1.34e-011.00e+002.8041141
GO:0007519skeletal muscle tissue development1.34e-011.00e+002.8041241
GO:0006367transcription initiation from RNA polymerase II promoter1.35e-011.00e+001.63825184
GO:0043565sequence-specific DNA binding1.35e-011.00e+001.23533365
GO:0006418tRNA aminoacylation for protein translation1.37e-011.00e+002.7691342
GO:0043547positive regulation of GTPase activity1.42e-011.00e+001.59222190
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process1.43e-011.00e+002.7021144
GO:0006892post-Golgi vesicle-mediated transport1.43e-011.00e+002.7021144
GO:0015030Cajal body1.46e-011.00e+002.6701145
GO:0016328lateral plasma membrane1.49e-011.00e+002.6381146
GO:0044297cell body1.49e-011.00e+002.6381146
GO:0006283transcription-coupled nucleotide-excision repair1.49e-011.00e+002.6381146
GO:0006921cellular component disassembly involved in execution phase of apoptosis1.52e-011.00e+002.6071147
GO:0019827stem cell maintenance1.55e-011.00e+002.5771248
GO:0008630intrinsic apoptotic signaling pathway in response to DNA damage1.58e-011.00e+002.5471149
GO:0006521regulation of cellular amino acid metabolic process1.61e-011.00e+002.5181250
GO:0007254JNK cascade1.64e-011.00e+002.4891251
GO:0003684damaged DNA binding1.64e-011.00e+002.4891151
GO:0006986response to unfolded protein1.64e-011.00e+002.4891251
GO:0000902cell morphogenesis1.64e-011.00e+002.4891151
GO:0045732positive regulation of protein catabolic process1.64e-011.00e+002.4891151
GO:0001701in utero embryonic development1.67e-011.00e+001.44722210
GO:0045454cell redox homeostasis1.67e-011.00e+002.4611152
GO:0004197cysteine-type endopeptidase activity1.67e-011.00e+002.4611152
GO:0034976response to endoplasmic reticulum stress1.67e-011.00e+002.4611152
GO:0009611response to wounding1.69e-011.00e+002.4341153
GO:0060041retina development in camera-type eye1.69e-011.00e+002.4341153
GO:0000288nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay1.69e-011.00e+002.4341253
GO:0090305nucleic acid phosphodiester bond hydrolysis1.72e-011.00e+002.4071154
GO:0051403stress-activated MAPK cascade1.72e-011.00e+002.4071254
GO:0008233peptidase activity1.75e-011.00e+002.3801155
GO:0000226microtubule cytoskeleton organization1.75e-011.00e+002.3801255
GO:0006814sodium ion transport1.75e-011.00e+002.3801155
GO:0000932cytoplasmic mRNA processing body1.78e-011.00e+002.3541256
GO:0000502proteasome complex1.84e-011.00e+002.3041258
GO:0035725sodium ion transmembrane transport1.84e-011.00e+002.3041158
GO:0016874ligase activity1.84e-011.00e+001.35424224
GO:0006351transcription, DNA-templated1.85e-011.00e+000.5318171585
GO:0005622intracellular1.87e-011.00e+001.34122226
GO:0003677DNA binding1.90e-011.00e+000.5697161351
GO:0005524ATP binding1.91e-011.00e+000.5667131354
GO:0032481positive regulation of type I interferon production1.92e-011.00e+002.2311261
GO:0007067mitotic nuclear division1.93e-011.00e+001.31024231
GO:0006987activation of signaling protein activity involved in unfolded protein response1.95e-011.00e+002.2071262
GO:0000151ubiquitin ligase complex1.98e-011.00e+002.1841263
GO:0006417regulation of translation1.98e-011.00e+002.1841163
GO:0019903protein phosphatase binding1.98e-011.00e+002.1841163
GO:0034146toll-like receptor 5 signaling pathway2.04e-011.00e+002.1391265
GO:0034166toll-like receptor 10 signaling pathway2.04e-011.00e+002.1391265
GO:0006469negative regulation of protein kinase activity2.04e-011.00e+002.1391265
GO:0071260cellular response to mechanical stimulus2.07e-011.00e+002.1171166
GO:0009636response to toxic substance2.07e-011.00e+002.1171166
GO:0007409axonogenesis2.07e-011.00e+002.1171166
GO:0008134transcription factor binding2.12e-011.00e+001.21926246
GO:0000777condensed chromosome kinetochore2.12e-011.00e+002.0741168
GO:0006338chromatin remodeling2.12e-011.00e+002.0741168
GO:0003697single-stranded DNA binding2.15e-011.00e+002.0531269
GO:0018105peptidyl-serine phosphorylation2.15e-011.00e+002.0531169
GO:0006289nucleotide-excision repair2.15e-011.00e+002.0531169
GO:0006887exocytosis2.15e-011.00e+002.0531169
GO:0000786nucleosome2.18e-011.00e+002.0321170
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway2.20e-011.00e+002.0121271
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway2.20e-011.00e+002.0121271
GO:0034162toll-like receptor 9 signaling pathway2.23e-011.00e+001.9921272
GO:0032587ruffle membrane2.23e-011.00e+001.9921172
GO:0010468regulation of gene expression2.23e-011.00e+001.9921172
GO:0034134toll-like receptor 2 signaling pathway2.26e-011.00e+001.9721273
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent2.26e-011.00e+001.9721273
GO:0000785chromatin2.26e-011.00e+001.9721273
GO:0042826histone deacetylase binding2.29e-011.00e+001.9521274
GO:0007265Ras protein signal transduction2.31e-011.00e+001.9331275
GO:0005730nucleolus2.31e-011.00e+000.4448281684
GO:0060070canonical Wnt signaling pathway2.31e-011.00e+001.9331275
GO:0035666TRIF-dependent toll-like receptor signaling pathway2.34e-011.00e+001.9141276
GO:0006281DNA repair2.35e-011.00e+001.11724264
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I2.37e-011.00e+001.8951277
GO:0008584male gonad development2.37e-011.00e+001.8951177
GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activity2.37e-011.00e+001.8951277
GO:0002756MyD88-independent toll-like receptor signaling pathway2.39e-011.00e+001.8761278
GO:0001822kidney development2.42e-011.00e+001.8581279
GO:0006334nucleosome assembly2.42e-011.00e+001.8581379
GO:0045893positive regulation of transcription, DNA-templated2.42e-011.00e+000.81936487
GO:0042802identical protein binding2.45e-011.00e+000.80736491
GO:0002755MyD88-dependent toll-like receptor signaling pathway2.45e-011.00e+001.8401380
GO:0034138toll-like receptor 3 signaling pathway2.45e-011.00e+001.8401280
GO:0000166nucleotide binding2.46e-011.00e+001.07426272
GO:0051301cell division2.47e-011.00e+001.8221281
GO:0048011neurotrophin TRK receptor signaling pathway2.47e-011.00e+001.06922273
GO:0030968endoplasmic reticulum unfolded protein response2.47e-011.00e+001.8221281
GO:0043065positive regulation of apoptotic process2.48e-011.00e+001.06423274
GO:0006357regulation of transcription from RNA polymerase II promoter2.50e-011.00e+001.05824275
GO:0007517muscle organ development2.53e-011.00e+001.7871183
GO:0009952anterior/posterior pattern specification2.55e-011.00e+001.7691284
GO:0009653anatomical structure morphogenesis2.63e-011.00e+001.7191187
GO:0019899enzyme binding2.66e-011.00e+000.99223288
GO:0006464cellular protein modification process2.68e-011.00e+001.6861189
GO:0005777peroxisome2.71e-011.00e+001.6701190
GO:0000187activation of MAPK activity2.71e-011.00e+001.6701290
GO:0000922spindle pole2.73e-011.00e+001.6541191
GO:0016337single organismal cell-cell adhesion2.76e-011.00e+001.6381192
GO:0006928cellular component movement2.76e-011.00e+001.6381192
GO:0016363nuclear matrix2.76e-011.00e+001.6381592
GO:0005923tight junction2.76e-011.00e+001.6381192
GO:0002474antigen processing and presentation of peptide antigen via MHC class I2.81e-011.00e+001.6071294
GO:0005770late endosome2.81e-011.00e+001.6071194
GO:0005743mitochondrial inner membrane2.82e-011.00e+000.93323300
GO:0051082unfolded protein binding2.83e-011.00e+001.5921395
GO:0034142toll-like receptor 4 signaling pathway2.86e-011.00e+001.5771296
GO:0006364rRNA processing2.86e-011.00e+001.5771296
GO:0071456cellular response to hypoxia2.91e-011.00e+001.5471298
GO:0006470protein dephosphorylation2.93e-011.00e+001.5321199
GO:0051726regulation of cell cycle3.01e-011.00e+001.48914102
GO:0016023cytoplasmic membrane-bounded vesicle3.13e-011.00e+001.42011107
GO:0045944positive regulation of transcription from RNA polymerase II promoter3.14e-011.00e+000.498413811
GO:0006935chemotaxis3.16e-011.00e+001.40711108
GO:0008270zinc ion binding3.16e-011.00e+000.4245111067
GO:0007411axon guidance3.17e-011.00e+000.80822327
GO:0002224toll-like receptor signaling pathway3.18e-011.00e+001.39312109
GO:0005938cell cortex3.18e-011.00e+001.39311109
GO:0006461protein complex assembly3.23e-011.00e+001.36712111
GO:0007605sensory perception of sound3.23e-011.00e+001.36711111
GO:0034765regulation of ion transmembrane transport3.27e-011.00e+001.34111113
GO:0030308negative regulation of cell growth3.27e-011.00e+001.34112113
GO:0005813centrosome3.32e-011.00e+000.75624339
GO:0097190apoptotic signaling pathway3.35e-011.00e+001.30411116
GO:0000122negative regulation of transcription from RNA polymerase II promoter3.39e-011.00e+000.544310589
GO:0004252serine-type endopeptidase activity3.42e-011.00e+001.26711119
GO:0006006glucose metabolic process3.42e-011.00e+001.26711119
GO:0003676nucleic acid binding3.48e-011.00e+001.23112122
GO:0006325chromatin organization3.51e-011.00e+001.21913123
GO:0007568aging3.51e-011.00e+001.21912123
GO:0006260DNA replication3.55e-011.00e+001.19614125
GO:0006805xenobiotic metabolic process3.64e-011.00e+001.15011129
GO:0030027lamellipodium3.67e-011.00e+001.13911130
GO:0008285negative regulation of cell proliferation3.68e-011.00e+000.64224367
GO:0016477cell migration3.69e-011.00e+001.12812131
GO:0046983protein dimerization activity3.69e-011.00e+001.12811131
GO:0031982vesicle3.75e-011.00e+001.09512134
GO:0044255cellular lipid metabolic process3.89e-011.00e+001.03211140
GO:0045202synapse3.89e-011.00e+001.03211140
GO:0061024membrane organization4.01e-011.00e+000.97211146
GO:0010628positive regulation of gene expression4.08e-011.00e+000.94212149
GO:0006457protein folding4.08e-011.00e+000.94211149
GO:0046982protein heterodimerization activity4.08e-011.00e+000.52123399
GO:0007166cell surface receptor signaling pathway4.08e-011.00e+000.94211149
GO:0051260protein homooligomerization4.10e-011.00e+000.93311150
GO:0006508proteolysis4.21e-011.00e+000.48222410
GO:0007165signal transduction4.26e-011.00e+000.27048950
GO:0043005neuron projection4.32e-011.00e+000.83114161
GO:0043066negative regulation of apoptotic process4.49e-011.00e+000.40325433
GO:0007420brain development4.54e-011.00e+000.73511172
GO:0034641cellular nitrogen compound metabolic process4.63e-011.00e+000.69413177
GO:0005667transcription factor complex4.65e-011.00e+000.68613178
GO:0031625ubiquitin protein ligase binding4.69e-011.00e+000.67012180
GO:0019904protein domain specific binding4.71e-011.00e+000.66212181
GO:0001525angiogenesis5.05e-011.00e+000.51811200
GO:0003924GTPase activity5.11e-011.00e+000.49612203
GO:0030168platelet activation5.14e-011.00e+000.48211205
GO:0070062extracellular vesicular exosome5.25e-011.00e+000.0359152516
GO:0006184GTP catabolic process5.39e-011.00e+000.38012220
GO:0005759mitochondrial matrix5.60e-011.00e+000.29714233
GO:0003713transcription coactivator activity5.69e-011.00e+000.26117239
GO:0030425dendrite5.71e-011.00e+000.25511240
GO:0007399nervous system development5.78e-011.00e+000.22513245
GO:0043025neuronal cell body5.92e-011.00e+000.17313254
GO:0005874microtubule5.97e-011.00e+000.15013258
GO:0003779actin binding6.21e-011.00e+000.05811275
GO:0045087innate immune response6.39e-011.00e+00-0.10524616
GO:0043234protein complex6.53e-011.00e+00-0.06714300
GO:0004674protein serine/threonine kinase activity6.68e-011.00e+00-0.12412312
GO:0044281small molecule metabolic process6.73e-011.00e+00-0.1774121295
GO:0035556intracellular signal transduction6.74e-011.00e+00-0.14712317
GO:0019901protein kinase binding6.77e-011.00e+00-0.16014320
GO:0005575cellular_component6.79e-011.00e+00-0.16911322
GO:0030154cell differentiation6.83e-011.00e+00-0.18312325
GO:0008283cell proliferation6.90e-011.00e+00-0.20913331
GO:0043231intracellular membrane-bounded organelle6.91e-011.00e+00-0.21311332
GO:0015031protein transport7.17e-011.00e+00-0.31812357
GO:0005925focal adhesion7.30e-011.00e+00-0.37012370
GO:0007155cell adhesion7.43e-011.00e+00-0.42312384
GO:0009986cell surface7.76e-011.00e+00-0.56014422
GO:0007596blood coagulation8.07e-011.00e+00-0.69611464
GO:0055114oxidation-reduction process8.19e-011.00e+00-0.74812481
GO:0003674molecular_function8.45e-011.00e+00-0.87211524
GO:0005615extracellular space8.76e-011.00e+00-0.819241010
GO:0005783endoplasmic reticulum8.86e-011.00e+00-1.09112610
GO:0046872metal ion binding8.96e-011.00e+00-0.770361465
GO:0005794Golgi apparatus9.02e-011.00e+00-1.18311650
GO:0005886plasma membrane9.46e-011.00e+00-0.7226142834
GO:0005887integral component of plasma membrane9.69e-011.00e+00-1.74711961
GO:0016021integral component of membrane9.95e-011.00e+00-1.531372483