int-snw-9094

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.908	2.69e-16	1.97e-04	1.79e-03

chia-screen-data-Fav-int-snw-9094 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
PSMD2	5708	47	-4.172	3.157	386	Yes	Yes
[ UNC119 ]	9094	1	-1.995	2.908	97	-	-
EIF2S2	8894	9	-2.999	2.968	81	Yes	Yes
ZFP64	55734	3	-3.174	2.908	14	Yes	Yes
CDC42	998	9	-2.199	3.119	265	Yes	Yes

Interactions (4)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
UNC119	9094	ZFP64	55734	pp	--	int.Intact: MI:0915(physical association); int.I2D: HPRD, IntAct, BioGrid, StelzlHigh; int.HPRD: yeast 2-hybrid
CDC42	998	UNC119	9094	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid, HPRD, StelzlHigh, IntAct; int.HPRD: yeast 2-hybrid
PSMD2	5708	UNC119	9094	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid, StelzlHigh, HPRD, IntAct; int.HPRD: yeast 2-hybrid
EIF2S2	8894	UNC119	9094	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid, HPRD, MINT, StelzlHigh, IntAct; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid

Related GO terms (145)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0051233	spindle midzone	1.01e-05	1.45e-01	8.587	2	2	15
GO:0042176	regulation of protein catabolic process	1.15e-05	1.66e-01	8.494	2	2	16
GO:1900186	negative regulation of clathrin-mediated endocytosis	3.47e-04	1.00e+00	11.494	1	1	1
GO:2001287	negative regulation of caveolin-mediated endocytosis	3.47e-04	1.00e+00	11.494	1	1	1
GO:0071338	positive regulation of hair follicle cell proliferation	6.93e-04	1.00e+00	10.494	1	1	2
GO:0090135	actin filament branching	6.93e-04	1.00e+00	10.494	1	1	2
GO:0002176	male germ cell proliferation	6.93e-04	1.00e+00	10.494	1	1	2
GO:0060661	submandibular salivary gland formation	6.93e-04	1.00e+00	10.494	1	1	2
GO:0005850	eukaryotic translation initiation factor 2 complex	1.04e-03	1.00e+00	9.909	1	1	3
GO:0051683	establishment of Golgi localization	1.04e-03	1.00e+00	9.909	1	1	3
GO:0034191	apolipoprotein A-I receptor binding	1.04e-03	1.00e+00	9.909	1	1	3
GO:0003161	cardiac conduction system development	1.04e-03	1.00e+00	9.909	1	1	3
GO:0007109	cytokinesis, completion of separation	1.04e-03	1.00e+00	9.909	1	1	3
GO:0060684	epithelial-mesenchymal cell signaling	1.39e-03	1.00e+00	9.494	1	1	4
GO:0051835	positive regulation of synapse structural plasticity	1.39e-03	1.00e+00	9.494	1	1	4
GO:0048664	neuron fate determination	1.39e-03	1.00e+00	9.494	1	1	4
GO:0072384	organelle transport along microtubule	1.39e-03	1.00e+00	9.494	1	1	4
GO:0035088	establishment or maintenance of apical/basal cell polarity	1.73e-03	1.00e+00	9.172	1	1	5
GO:0036336	dendritic cell migration	1.73e-03	1.00e+00	9.172	1	1	5
GO:0031256	leading edge membrane	1.73e-03	1.00e+00	9.172	1	1	5
GO:0060789	hair follicle placode formation	2.08e-03	1.00e+00	8.909	1	2	6
GO:0007097	nuclear migration	2.08e-03	1.00e+00	8.909	1	1	6
GO:0003334	keratinocyte development	2.08e-03	1.00e+00	8.909	1	1	6
GO:0048554	positive regulation of metalloenzyme activity	2.08e-03	1.00e+00	8.909	1	1	6
GO:0043497	regulation of protein heterodimerization activity	2.08e-03	1.00e+00	8.909	1	1	6
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	2.42e-03	1.00e+00	8.687	1	2	7
GO:0051489	regulation of filopodium assembly	2.42e-03	1.00e+00	8.687	1	1	7
GO:0090136	epithelial cell-cell adhesion	3.12e-03	1.00e+00	8.324	1	1	9
GO:0031274	positive regulation of pseudopodium assembly	3.46e-03	1.00e+00	8.172	1	2	10
GO:0060047	heart contraction	3.46e-03	1.00e+00	8.172	1	1	10
GO:0005829	cytosol	3.86e-03	1.00e+00	2.209	4	86	2496
GO:0005838	proteasome regulatory particle	4.15e-03	1.00e+00	7.909	1	1	12
GO:0042953	lipoprotein transport	4.15e-03	1.00e+00	7.909	1	2	12
GO:0030234	enzyme regulator activity	4.50e-03	1.00e+00	7.794	1	2	13
GO:0031333	negative regulation of protein complex assembly	4.84e-03	1.00e+00	7.687	1	1	14
GO:0031996	thioesterase binding	4.84e-03	1.00e+00	7.687	1	1	14
GO:0030225	macrophage differentiation	5.19e-03	1.00e+00	7.587	1	2	15
GO:0030742	GTP-dependent protein binding	5.88e-03	1.00e+00	7.407	1	1	17
GO:0090316	positive regulation of intracellular protein transport	5.88e-03	1.00e+00	7.407	1	2	17
GO:0022624	proteasome accessory complex	5.88e-03	1.00e+00	7.407	1	1	17
GO:0007602	phototransduction	5.88e-03	1.00e+00	7.407	1	1	17
GO:0007088	regulation of mitosis	6.23e-03	1.00e+00	7.324	1	1	18
GO:0046847	filopodium assembly	6.57e-03	1.00e+00	7.246	1	1	19
GO:0061098	positive regulation of protein tyrosine kinase activity	7.26e-03	1.00e+00	7.102	1	1	21
GO:0031435	mitogen-activated protein kinase kinase kinase binding	7.26e-03	1.00e+00	7.102	1	1	21
GO:0031424	keratinization	7.60e-03	1.00e+00	7.035	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	7.60e-03	1.00e+00	7.035	1	2	22
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	7.95e-03	1.00e+00	6.971	1	3	23
GO:0002040	sprouting angiogenesis	7.95e-03	1.00e+00	6.971	1	2	23
GO:0051017	actin filament bundle assembly	7.95e-03	1.00e+00	6.971	1	1	23
GO:0007163	establishment or maintenance of cell polarity	8.29e-03	1.00e+00	6.909	1	2	24
GO:0008135	translation factor activity, nucleic acid binding	8.29e-03	1.00e+00	6.909	1	3	24
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	8.98e-03	1.00e+00	6.794	1	3	26
GO:0045859	regulation of protein kinase activity	8.98e-03	1.00e+00	6.794	1	1	26
GO:0051149	positive regulation of muscle cell differentiation	9.33e-03	1.00e+00	6.739	1	4	27
GO:0032467	positive regulation of cytokinesis	9.33e-03	1.00e+00	6.739	1	2	27
GO:0031069	hair follicle morphogenesis	9.33e-03	1.00e+00	6.739	1	1	27
GO:0072686	mitotic spindle	1.00e-02	1.00e+00	6.636	1	3	29
GO:0045171	intercellular bridge	1.04e-02	1.00e+00	6.587	1	1	30
GO:0031647	regulation of protein stability	1.04e-02	1.00e+00	6.587	1	4	30
GO:0042692	muscle cell differentiation	1.17e-02	1.00e+00	6.407	1	4	34
GO:0034332	adherens junction organization	1.24e-02	1.00e+00	6.324	1	2	36
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	1.24e-02	1.00e+00	6.324	1	2	36
GO:0045740	positive regulation of DNA replication	1.24e-02	1.00e+00	6.324	1	1	36
GO:0021762	substantia nigra development	1.52e-02	1.00e+00	6.035	1	4	44
GO:0034613	cellular protein localization	1.52e-02	1.00e+00	6.035	1	2	44
GO:0043525	positive regulation of neuron apoptotic process	1.58e-02	1.00e+00	5.971	1	4	46
GO:0007030	Golgi organization	1.69e-02	1.00e+00	5.879	1	3	49
GO:0003743	translation initiation factor activity	1.69e-02	1.00e+00	5.879	1	7	49
GO:0030175	filopodium	1.72e-02	1.00e+00	5.850	1	1	50
GO:0006521	regulation of cellular amino acid metabolic process	1.72e-02	1.00e+00	5.850	1	1	50
GO:0046330	positive regulation of JNK cascade	1.89e-02	1.00e+00	5.713	1	2	55
GO:0010467	gene expression	1.96e-02	1.00e+00	3.108	2	45	669
GO:0000502	proteasome complex	1.99e-02	1.00e+00	5.636	1	3	58
GO:0033138	positive regulation of peptidyl-serine phosphorylation	2.03e-02	1.00e+00	5.612	1	2	59
GO:0030141	secretory granule	2.13e-02	1.00e+00	5.540	1	4	62
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	2.20e-02	1.00e+00	5.494	1	1	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.23e-02	1.00e+00	5.472	1	2	65
GO:0031295	T cell costimulation	2.23e-02	1.00e+00	5.472	1	1	65
GO:0035264	multicellular organism growth	2.30e-02	1.00e+00	5.428	1	2	67
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.40e-02	1.00e+00	5.365	1	2	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	2.47e-02	1.00e+00	5.324	1	1	72
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	2.54e-02	1.00e+00	5.285	1	2	74
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.54e-02	1.00e+00	5.285	1	2	74
GO:0008584	male gonad development	2.57e-02	1.00e+00	5.265	1	3	75
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	2.57e-02	1.00e+00	5.265	1	1	75
GO:0060070	canonical Wnt signaling pathway	2.57e-02	1.00e+00	5.265	1	4	75
GO:0010629	negative regulation of gene expression	2.64e-02	1.00e+00	5.227	1	4	77
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	2.71e-02	1.00e+00	5.190	1	2	79
GO:0045177	apical part of cell	2.78e-02	1.00e+00	5.154	1	3	81
GO:0000922	spindle pole	2.98e-02	1.00e+00	5.051	1	4	87
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	3.15e-02	1.00e+00	4.971	1	1	92
GO:0008289	lipid binding	3.62e-02	1.00e+00	4.766	1	1	106
GO:0006897	endocytosis	3.62e-02	1.00e+00	4.766	1	7	106
GO:0030496	midbody	3.69e-02	1.00e+00	4.739	1	2	108
GO:0005815	microtubule organizing center	3.72e-02	1.00e+00	4.726	1	3	109
GO:0051056	regulation of small GTPase mediated signal transduction	3.92e-02	1.00e+00	4.649	1	3	115
GO:0000209	protein polyubiquitination	3.96e-02	1.00e+00	4.636	1	3	116
GO:0030036	actin cytoskeleton organization	4.19e-02	1.00e+00	4.552	1	3	123
GO:0006413	translational initiation	4.46e-02	1.00e+00	4.461	1	7	131
GO:0005911	cell-cell junction	4.63e-02	1.00e+00	4.407	1	2	136
GO:0010628	positive regulation of gene expression	4.96e-02	1.00e+00	4.304	1	7	146
GO:0000082	G1/S transition of mitotic cell cycle	5.06e-02	1.00e+00	4.275	1	3	149
GO:0042981	regulation of apoptotic process	5.09e-02	1.00e+00	4.265	1	4	150
GO:0007601	visual perception	5.33e-02	1.00e+00	4.200	1	5	157
GO:0043005	neuron projection	5.33e-02	1.00e+00	4.200	1	3	157
GO:0034641	cellular nitrogen compound metabolic process	5.79e-02	1.00e+00	4.076	1	2	171
GO:0007173	epidermal growth factor receptor signaling pathway	6.38e-02	1.00e+00	3.932	1	5	189
GO:0003924	GTPase activity	6.65e-02	1.00e+00	3.872	1	7	197
GO:0001701	in utero embryonic development	6.78e-02	1.00e+00	3.843	1	8	201
GO:0046872	metal ion binding	6.82e-02	1.00e+00	2.142	2	29	1307
GO:0006184	GTP catabolic process	7.20e-02	1.00e+00	3.753	1	7	214
GO:0016071	mRNA metabolic process	7.50e-02	1.00e+00	3.693	1	8	223
GO:0006412	translation	7.72e-02	1.00e+00	3.649	1	8	230
GO:0043025	neuronal cell body	8.21e-02	1.00e+00	3.558	1	9	245
GO:0016070	RNA metabolic process	8.28e-02	1.00e+00	3.546	1	8	247
GO:0007264	small GTPase mediated signal transduction	9.31e-02	1.00e+00	3.370	1	3	279
GO:0005515	protein binding	1.01e-01	1.00e+00	0.938	4	198	6024
GO:0005525	GTP binding	1.03e-01	1.00e+00	3.218	1	12	310
GO:0019901	protein kinase binding	1.05e-01	1.00e+00	3.186	1	18	317
GO:0007411	axon guidance	1.06e-01	1.00e+00	3.177	1	5	319
GO:0016020	membrane	1.07e-01	1.00e+00	1.779	2	46	1681
GO:0005813	centrosome	1.08e-01	1.00e+00	3.145	1	7	326
GO:0007268	synaptic transmission	1.10e-01	1.00e+00	3.119	1	5	332
GO:0003723	RNA binding	1.13e-01	1.00e+00	3.076	1	18	342
GO:0000139	Golgi membrane	1.19e-01	1.00e+00	2.998	1	7	361
GO:0005925	focal adhesion	1.21e-01	1.00e+00	2.978	1	9	366
GO:0000278	mitotic cell cycle	1.28e-01	1.00e+00	2.883	1	15	391
GO:0043066	negative regulation of apoptotic process	1.39e-01	1.00e+00	2.766	1	16	424
GO:0007596	blood coagulation	1.48e-01	1.00e+00	2.664	1	11	455
GO:0044267	cellular protein metabolic process	1.54e-01	1.00e+00	2.605	1	20	474
GO:0042802	identical protein binding	1.57e-01	1.00e+00	2.575	1	19	484
GO:0016032	viral process	1.72e-01	1.00e+00	2.433	1	26	534
GO:0006915	apoptotic process	1.78e-01	1.00e+00	2.378	1	12	555
GO:0045087	innate immune response	1.90e-01	1.00e+00	2.275	1	15	596
GO:0070062	extracellular vesicular exosome	1.96e-01	1.00e+00	1.265	2	57	2400
GO:0006355	regulation of transcription, DNA-templated	3.01e-01	1.00e+00	1.533	1	43	997
GO:0044822	poly(A) RNA binding	3.16e-01	1.00e+00	1.450	1	50	1056
GO:0005654	nucleoplasm	3.23e-01	1.00e+00	1.415	1	64	1082
GO:0044281	small molecule metabolic process	3.55e-01	1.00e+00	1.252	1	20	1211
GO:0003677	DNA binding	3.57e-01	1.00e+00	1.244	1	49	1218
GO:0006351	transcription, DNA-templated	4.10e-01	1.00e+00	0.996	1	57	1446
GO:0005886	plasma membrane	6.27e-01	1.00e+00	0.160	1	49	2582
GO:0005737	cytoplasm	7.80e-01	1.00e+00	-0.385	1	124	3767
GO:0005634	nucleus	8.50e-01	1.00e+00	-0.660	1	159	4559

chia-Fav

int-snw-9094

Statistics

Genes (5)

Interactions (4)

Related GO terms (145)