meta-reg-snw-8776

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
int-snw-6446 wolf-screen-ratio-mammosphere-adherent 0.930 2.55e-15 2.75e-03 4.33e-02 18 18
reg-snw-8776 wolf-screen-ratio-mammosphere-adherent 0.800 2.67e-06 5.08e-03 9.11e-03 5 5
wolf-screen-ratio-mammosphere-adherent-meta-reg-snw-8776 subnetwork

Genes (20)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
PSMA2 5683 1121.0931.106108Yes-
PAFAH1B1 5048 170.6910.819126Yes-
RBX1 9978 1151.1850.934148Yes-
PSMB7 5695 1180.9820.93490Yes-
PSMA1 5682 1000.9960.878152Yes-
VARS 7407 860.5491.002204Yes-
RPSA 3921 1201.3271.151152Yes-
RPS3A 6189 400.8351.069166Yes-
PSMA6 5687 190.6910.956137Yes-
RPS11 6205 620.9931.113175Yes-
PSMD3 5709 1000.9861.106201Yes-
RPL14 9045 491.2501.113166Yes-
SGK1 6446 17-0.1890.93076-Yes
GSK3B 2932 220.4750.934319-Yes
TUBG1 7283 980.9740.97391Yes-
PSMD11 5717 1241.0951.106218Yes-
ACTB 60 1341.1531.151610Yes-
SAP18 10284 201.1151.06957Yes-
PSMD6 9861 790.8480.878143Yes-
MTMR1 8776 20.0970.80049Yes-

Interactions (54)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMD11 5717 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, INTEROLOG
SGK1 6446 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMA6 5687 RBX1 9978 pp -- int.I2D: BioGrid
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
GSK3B 2932 SGK1 6446 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vitro, in vivo
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
RPS3A 6189 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastMedium
RPSA 3921 VARS 7407 pp -- int.I2D: IntAct_Yeast
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
GSK3B 2932 TUBG1 7283 pp -- int.I2D: MINT
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
TUBG1 7283 VARS 7407 pd < reg.ITFP.txt: no annot
PAFAH1B1 5048 RPL14 9045 pd > reg.ITFP.txt: no annot
PSMA2 5683 PSMA6 5687 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, HPRD, Krogan_Core, Tarassov_PCA, Yu_GoldStd;
int.HPRD: yeast 2-hybrid
SGK1 6446 VARS 7407 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS3A 6189 SAP18 10284 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid, HPRD, MINT;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
RPS3A 6189 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 RBX1 9978 pd < reg.ITFP.txt: no annot
PSMD3 5709 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMA6 5687 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMD3 5709 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Yeast, MINT_Worm, MINT_Yeast, YeastHigh, BioGrid, BIND_Yeast, IntAct_Worm, INTEROLOG, Krogan_Core, MIPS
RPS3A 6189 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PAFAH1B1 5048 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
PSMD3 5709 VARS 7407 pd <> reg.ITFP.txt: no annot
ACTB 60 PSMA6 5687 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMA1 5682 PSMA6 5687 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, YeastHigh, IntAct_Worm, Krogan_Core, MINT_Yeast;
int.Mint: MI:0914(association)
PSMD11 5717 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMA6 5687 SGK1 6446 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct
PAFAH1B1 5048 MTMR1 8776 pd > reg.ITFP.txt: no annot
ACTB 60 RPS3A 6189 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPS3A 6189 SGK1 6446 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMA6 5687 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, BIND_Yeast, Krogan_Core, MINT_Yeast, YeastLow
PSMA2 5683 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow, BioGrid
PSMA6 5687 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow
PSMD3 5709 MTMR1 8776 pd > reg.ITFP.txt: no annot
RPSA 3921 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMA6 5687 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow

Related GO terms (331)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0016071mRNA metabolic process3.65e-165.95e-125.3311134223
GO:0016070RNA metabolic process1.14e-151.86e-115.1841134247
GO:0005829cytosol8.47e-151.38e-102.597191252562
GO:0006521regulation of cellular amino acid metabolic process1.23e-132.01e-096.83672150
GO:0016032viral process1.51e-132.46e-094.1811255540
GO:0000502proteasome complex3.68e-136.01e-096.62272258
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle8.48e-131.38e-086.45872465
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest8.48e-131.38e-086.45872265
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.45e-122.37e-086.35172470
GO:0010467gene expression1.90e-123.11e-083.8721258669
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent1.97e-123.22e-086.29072373
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.18e-123.55e-086.27072474
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I2.90e-124.74e-086.21372377
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process3.50e-125.71e-086.17672579
GO:0042981regulation of apoptotic process5.11e-128.34e-085.434826151
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.22e-111.99e-075.92572394
GO:0000209protein polyubiquitination5.48e-118.94e-075.622721116
GO:0000082G1/S transition of mitotic cell cycle3.37e-105.51e-065.251733150
GO:0000278mitotic cell cycle3.69e-106.03e-064.206952398
GO:0043066negative regulation of apoptotic process7.77e-101.27e-054.084930433
GO:0034641cellular nitrogen compound metabolic process1.08e-091.76e-055.012725177
GO:0005839proteasome core complex4.96e-098.10e-057.50341118
GO:0004298threonine-type endopeptidase activity7.84e-091.28e-047.35141120
GO:0019773proteasome core complex, alpha-subunit complex8.78e-081.43e-038.257358
GO:0006915apoptotic process1.86e-073.03e-033.515834571
GO:0070062extracellular vesicular exosome7.17e-071.17e-022.07613982516
GO:0022624proteasome accessory complex1.06e-061.73e-027.1703917
GO:0005654nucleoplasm2.28e-063.72e-022.7469831095
GO:0019083viral transcription2.57e-064.19e-025.3334881
GO:0006415translational termination3.42e-065.58e-025.2304887
GO:0006414translational elongation4.46e-067.28e-025.13341193
GO:0006614SRP-dependent cotranslational protein targeting to membrane6.97e-061.14e-014.97248104
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.00e-051.64e-014.840410114
GO:0019058viral life cycle1.04e-051.70e-014.827410115
GO:0022627cytosolic small ribosomal subunit1.40e-052.28e-015.9723339
GO:0006413translational initiation1.74e-052.84e-014.639412131
GO:0003735structural constituent of ribosome2.32e-053.79e-014.53348141
GO:0044281small molecule metabolic process8.14e-051.00e+002.3348571295
GO:0005838proteasome regulatory particle9.35e-051.00e+007.0882712
GO:0006412translation1.69e-041.00e+003.796415235
GO:0044267cellular protein metabolic process2.67e-041.00e+003.043524495
GO:0030529ribonucleoprotein complex3.47e-041.00e+004.42538114
GO:0005844polysome4.21e-041.00e+006.0292425
GO:0051059NF-kappaB binding4.21e-041.00e+006.0292325
GO:0005813centrosome6.81e-041.00e+003.267412339
GO:0005515protein binding7.38e-041.00e+000.998151726127
GO:0003723RNA binding8.09e-041.00e+003.201419355
GO:0021766hippocampus development1.03e-031.00e+005.3872439
GO:0000235astral microtubule1.23e-031.00e+009.673111
GO:0051660establishment of centrosome localization1.23e-031.00e+009.673111
GO:0035639purine ribonucleoside triphosphate binding1.23e-031.00e+009.673111
GO:0060453regulation of gastric acid secretion1.23e-031.00e+009.673111
GO:0046469platelet activating factor metabolic process1.23e-031.00e+009.673111
GO:0000226microtubule cytoskeleton organization2.04e-031.00e+004.8912355
GO:0000932cytoplasmic mRNA processing body2.11e-031.00e+004.8652356
GO:0004832valine-tRNA ligase activity2.45e-031.00e+008.673112
GO:0051081nuclear envelope disassembly2.45e-031.00e+008.673112
GO:0044337canonical Wnt signaling pathway involved in positive regulation of apoptotic process2.45e-031.00e+008.673122
GO:0006407rRNA export from nucleus2.45e-031.00e+008.673112
GO:0006438valyl-tRNA aminoacylation2.45e-031.00e+008.673112
GO:0036035osteoclast development2.45e-031.00e+008.673122
GO:0071109superior temporal gyrus development2.45e-031.00e+008.673112
GO:2000077negative regulation of type B pancreatic cell development2.45e-031.00e+008.673112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2.45e-031.00e+008.673112
GO:0005055laminin receptor activity2.45e-031.00e+008.673112
GO:0005737cytoplasm3.15e-031.00e+001.17511983976
GO:0061574ASAP complex3.67e-031.00e+008.088113
GO:0014043negative regulation of neuron maturation3.67e-031.00e+008.088113
GO:0000320re-entry into mitotic cell cycle3.67e-031.00e+008.088113
GO:2000466negative regulation of glycogen (starch) synthase activity3.67e-031.00e+008.088113
GO:0044027hypermethylation of CpG island3.67e-031.00e+008.088113
GO:0021540corpus callosum morphogenesis3.67e-031.00e+008.088113
GO:0045505dynein intermediate chain binding3.67e-031.00e+008.088113
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)4.89e-031.00e+007.673114
GO:0000212meiotic spindle organization4.89e-031.00e+007.673114
GO:003068690S preribosome4.89e-031.00e+007.673114
GO:0070294renal sodium ion absorption4.89e-031.00e+007.673114
GO:0019788NEDD8 ligase activity4.89e-031.00e+007.673114
GO:0031467Cul7-RING ubiquitin ligase complex4.89e-031.00e+007.673114
GO:0051534negative regulation of NFAT protein import into nucleus4.89e-031.00e+007.673114
GO:0005200structural constituent of cytoskeleton5.71e-031.00e+004.1332793
GO:0031465Cul4B-RING E3 ubiquitin ligase complex6.11e-031.00e+007.351125
GO:0031023microtubule organizing center organization6.11e-031.00e+007.351115
GO:0031461cullin-RING ubiquitin ligase complex6.11e-031.00e+007.351115
GO:0043248proteasome assembly6.11e-031.00e+007.351115
GO:0036016cellular response to interleukin-36.11e-031.00e+007.351115
GO:2000738positive regulation of stem cell differentiation6.11e-031.00e+007.351115
GO:0030891VCB complex6.11e-031.00e+007.351125
GO:0017081chloride channel regulator activity6.11e-031.00e+007.351115
GO:0005827polar microtubule6.11e-031.00e+007.351115
GO:0032411positive regulation of transporter activity6.11e-031.00e+007.351115
GO:0030426growth cone6.20e-031.00e+004.0732397
GO:0002181cytoplasmic translation7.33e-031.00e+007.088116
GO:0001667ameboidal-type cell migration7.33e-031.00e+007.088116
GO:0031466Cul5-RING ubiquitin ligase complex7.33e-031.00e+007.088116
GO:0008090retrograde axon cargo transport7.33e-031.00e+007.088116
GO:0050774negative regulation of dendrite morphogenesis7.33e-031.00e+007.088116
GO:0030957Tat protein binding7.33e-031.00e+007.088146
GO:0034452dynactin binding7.33e-031.00e+007.088116
GO:0010614negative regulation of cardiac muscle hypertrophy7.33e-031.00e+007.088116
GO:0044822poly(A) RNA binding8.38e-031.00e+001.9205501078
GO:0007097nuclear migration8.55e-031.00e+006.865117
GO:0001961positive regulation of cytokine-mediated signaling pathway8.55e-031.00e+006.865117
GO:0000028ribosomal small subunit assembly8.55e-031.00e+006.865117
GO:0002161aminoacyl-tRNA editing activity8.55e-031.00e+006.865127
GO:0031462Cul2-RING ubiquitin ligase complex8.55e-031.00e+006.865127
GO:0017145stem cell division8.55e-031.00e+006.865117
GO:0000930gamma-tubulin complex8.55e-031.00e+006.865117
GO:0031464Cul4A-RING E3 ubiquitin ligase complex9.76e-031.00e+006.673128
GO:0004438phosphatidylinositol-3-phosphatase activity9.76e-031.00e+006.673118
GO:0070688MLL5-L complex9.76e-031.00e+006.673118
GO:0045116protein neddylation9.76e-031.00e+006.673128
GO:0031512motile primary cilium9.76e-031.00e+006.673118
GO:1901030positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway9.76e-031.00e+006.673118
GO:0045719negative regulation of glycogen biosynthetic process9.76e-031.00e+006.673118
GO:0035372protein localization to microtubule9.76e-031.00e+006.673118
GO:0005925focal adhesion9.89e-031.00e+002.726318370
GO:0048156tau protein binding1.10e-021.00e+006.503119
GO:0006983ER overload response1.10e-021.00e+006.503129
GO:0032319regulation of Rho GTPase activity1.10e-021.00e+006.503129
GO:0021895cerebral cortex neuron differentiation1.10e-021.00e+006.503119
GO:0000086G2/M transition of mitotic cell cycle1.20e-021.00e+003.57427137
GO:0006450regulation of translational fidelity1.22e-021.00e+006.3511210
GO:0010226response to lithium ion1.22e-021.00e+006.3511210
GO:0001675acrosome assembly1.22e-021.00e+006.3511110
GO:0030877beta-catenin destruction complex1.22e-021.00e+006.3511210
GO:0005730nucleolus1.30e-021.00e+001.5406701684
GO:0045502dynein binding1.34e-021.00e+006.2131211
GO:0021819layer formation in cerebral cortex1.34e-021.00e+006.2131111
GO:0032886regulation of microtubule-based process1.46e-021.00e+006.0881412
GO:0034236protein kinase A catalytic subunit binding1.46e-021.00e+006.0881112
GO:0047496vesicle transport along microtubule1.46e-021.00e+006.0881112
GO:0050321tau-protein kinase activity1.46e-021.00e+006.0881112
GO:0005634nucleus1.53e-021.00e+000.895111314828
GO:0016020membrane1.54e-021.00e+001.4886801746
GO:0042273ribosomal large subunit biogenesis1.58e-021.00e+005.9721413
GO:0030234enzyme regulator activity1.58e-021.00e+005.9721313
GO:0046827positive regulation of protein export from nucleus1.58e-021.00e+005.9721213
GO:0035267NuA4 histone acetyltransferase complex1.70e-021.00e+005.8651414
GO:0031333negative regulation of protein complex assembly1.70e-021.00e+005.8651114
GO:0048168regulation of neuronal synaptic plasticity1.70e-021.00e+005.8651114
GO:0007020microtubule nucleation1.70e-021.00e+005.8651114
GO:0031334positive regulation of protein complex assembly1.70e-021.00e+005.8651214
GO:0006349regulation of gene expression by genetic imprinting1.82e-021.00e+005.7661115
GO:0048025negative regulation of mRNA splicing, via spliceosome1.82e-021.00e+005.7661115
GO:0048854brain morphogenesis1.82e-021.00e+005.7661115
GO:0030424axon1.85e-021.00e+003.24623172
GO:0007405neuroblast proliferation1.94e-021.00e+005.6731116
GO:0042176regulation of protein catabolic process1.94e-021.00e+005.6731316
GO:0007520myoblast fusion1.94e-021.00e+005.6731116
GO:0046856phosphatidylinositol dephosphorylation1.94e-021.00e+005.6731116
GO:0051603proteolysis involved in cellular protein catabolic process1.94e-021.00e+005.6731216
GO:0050998nitric-oxide synthase binding1.94e-021.00e+005.6731116
GO:0019226transmission of nerve impulse1.94e-021.00e+005.6731116
GO:0000132establishment of mitotic spindle orientation1.94e-021.00e+005.6731116
GO:0031625ubiquitin protein ligase binding2.02e-021.00e+003.181213180
GO:0035255ionotropic glutamate receptor binding2.06e-021.00e+005.5851117
GO:0043274phospholipase binding2.06e-021.00e+005.5851117
GO:0031122cytoplasmic microtubule organization2.18e-021.00e+005.5031218
GO:0005246calcium channel regulator activity2.18e-021.00e+005.5031118
GO:0010800positive regulation of peptidyl-threonine phosphorylation2.18e-021.00e+005.5031118
GO:0045773positive regulation of axon extension2.18e-021.00e+005.5031218
GO:0035145exon-exon junction complex2.30e-021.00e+005.4251219
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process2.30e-021.00e+005.4251119
GO:0048863stem cell differentiation2.30e-021.00e+005.4251119
GO:0051090regulation of sequence-specific DNA binding transcription factor activity2.42e-021.00e+005.3511120
GO:0009306protein secretion2.54e-021.00e+005.2801121
GO:0001954positive regulation of cell-matrix adhesion2.54e-021.00e+005.2801121
GO:0030010establishment of cell polarity2.54e-021.00e+005.2801221
GO:0017080sodium channel regulator activity2.66e-021.00e+005.2131122
GO:0030863cortical cytoskeleton2.66e-021.00e+005.2131122
GO:0036464cytoplasmic ribonucleoprotein granule2.66e-021.00e+005.2131422
GO:0031463Cul3-RING ubiquitin ligase complex2.78e-021.00e+005.1491223
GO:0043236laminin binding2.78e-021.00e+005.1491123
GO:0006513protein monoubiquitination2.78e-021.00e+005.1491123
GO:0043044ATP-dependent chromatin remodeling2.78e-021.00e+005.1491423
GO:0000794condensed nuclear chromosome2.90e-021.00e+005.0881224
GO:0046329negative regulation of JNK cascade2.90e-021.00e+005.0881124
GO:0005977glycogen metabolic process2.90e-021.00e+005.0881124
GO:0006611protein export from nucleus3.02e-021.00e+005.0291425
GO:0030016myofibril3.02e-021.00e+005.0291125
GO:0045931positive regulation of mitotic cell cycle3.14e-021.00e+004.9721126
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia3.14e-021.00e+004.9721226
GO:0015459potassium channel regulator activity3.14e-021.00e+004.9721126
GO:0007616long-term memory3.26e-021.00e+004.9181127
GO:0019843rRNA binding3.26e-021.00e+004.9181327
GO:0005875microtubule associated complex3.38e-021.00e+004.8651228
GO:0007017microtubule-based process3.38e-021.00e+004.8651328
GO:0043022ribosome binding3.38e-021.00e+004.8651328
GO:0031492nucleosomal DNA binding3.38e-021.00e+004.8651428
GO:0000118histone deacetylase complex3.38e-021.00e+004.8651128
GO:0019894kinesin binding3.38e-021.00e+004.8651128
GO:0000381regulation of alternative mRNA splicing, via spliceosome3.50e-021.00e+004.8151229
GO:0031252cell leading edge3.50e-021.00e+004.8151329
GO:0019005SCF ubiquitin ligase complex3.50e-021.00e+004.8151129
GO:0004712protein serine/threonine/tyrosine kinase activity3.50e-021.00e+004.8151129
GO:0043198dendritic shaft3.50e-021.00e+004.8151129
GO:0010977negative regulation of neuron projection development3.61e-021.00e+004.7661230
GO:0043025neuronal cell body3.81e-021.00e+002.68424254
GO:0051219phosphoprotein binding3.85e-021.00e+004.6731332
GO:1903507negative regulation of nucleic acid-templated transcription3.85e-021.00e+004.6731232
GO:0032091negative regulation of protein binding3.97e-021.00e+004.6281133
GO:0001837epithelial to mesenchymal transition3.97e-021.00e+004.6281133
GO:0043407negative regulation of MAP kinase activity4.09e-021.00e+004.5851134
GO:0007611learning or memory4.09e-021.00e+004.5851234
GO:0030017sarcomere4.09e-021.00e+004.5851134
GO:0001085RNA polymerase II transcription factor binding4.09e-021.00e+004.5851234
GO:0004175endopeptidase activity4.09e-021.00e+004.5851234
GO:0097192extrinsic apoptotic signaling pathway in absence of ligand4.21e-021.00e+004.5431235
GO:0034332adherens junction organization4.32e-021.00e+004.5031136
GO:0032855positive regulation of Rac GTPase activity4.32e-021.00e+004.5031136
GO:0001895retina homeostasis4.32e-021.00e+004.5031136
GO:0016301kinase activity4.44e-021.00e+004.4631337
GO:0051084'de novo' posttranslational protein folding4.44e-021.00e+004.4631437
GO:0070527platelet aggregation4.56e-021.00e+004.4251238
GO:0032092positive regulation of protein binding4.67e-021.00e+004.3871339
GO:0050885neuromuscular process controlling balance4.91e-021.00e+004.3151141
GO:0006418tRNA aminoacylation for protein translation5.03e-021.00e+004.2801542
GO:0021987cerebral cortex development5.03e-021.00e+004.2801342
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process5.26e-021.00e+004.2131344
GO:0005871kinesin complex5.26e-021.00e+004.2131244
GO:0021762substantia nigra development5.49e-021.00e+004.1491146
GO:0004674protein serine/threonine kinase activity5.52e-021.00e+002.38726312
GO:0050727regulation of inflammatory response5.61e-021.00e+004.1181347
GO:0008344adult locomotory behavior5.61e-021.00e+004.1181147
GO:0006950response to stress5.72e-021.00e+004.0881348
GO:0019901protein kinase binding5.77e-021.00e+002.351221320
GO:0022625cytosolic large ribosomal subunit5.84e-021.00e+004.0581549
GO:0007411axon guidance6.00e-021.00e+002.31929327
GO:0045444fat cell differentiation6.07e-021.00e+004.0001151
GO:0045732positive regulation of protein catabolic process6.07e-021.00e+004.0001451
GO:0016042lipid catabolic process6.19e-021.00e+003.9721152
GO:0030334regulation of cell migration6.19e-021.00e+003.9721252
GO:0007623circadian rhythm6.42e-021.00e+003.9181154
GO:0006661phosphatidylinositol biosynthetic process6.42e-021.00e+003.9181154
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding6.42e-021.00e+003.9181554
GO:0002039p53 binding6.53e-021.00e+003.8911755
GO:0006814sodium ion transport6.53e-021.00e+003.8911155
GO:0008217regulation of blood pressure6.88e-021.00e+003.8151558
GO:0005840ribosome6.99e-021.00e+003.7901259
GO:0045216cell-cell junction organization6.99e-021.00e+003.7901259
GO:0008013beta-catenin binding7.11e-021.00e+003.7661460
GO:0033138positive regulation of peptidyl-serine phosphorylation7.22e-021.00e+003.7421361
GO:0000776kinetochore7.45e-021.00e+003.6951463
GO:0001558regulation of cell growth7.79e-021.00e+003.6281466
GO:0071260cellular response to mechanical stimulus7.79e-021.00e+003.6281466
GO:0005524ATP binding7.85e-021.00e+001.2704461354
GO:0018105peptidyl-serine phosphorylation8.13e-021.00e+003.5641169
GO:0050790regulation of catalytic activity8.13e-021.00e+003.5641369
GO:0034329cell junction assembly8.35e-021.00e+003.5231171
GO:0060070canonical Wnt signaling pathway8.81e-021.00e+003.4441375
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process8.92e-021.00e+003.4251376
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis9.03e-021.00e+003.4061577
GO:0004725protein tyrosine phosphatase activity9.37e-021.00e+003.3511280
GO:0043197dendritic spine9.70e-021.00e+003.2971283
GO:0090090negative regulation of canonical Wnt signaling pathway1.03e-011.00e+003.2131388
GO:0009887organ morphogenesis1.04e-011.00e+003.1971289
GO:0016363nuclear matrix1.07e-011.00e+003.14911192
GO:0006928cellular component movement1.07e-011.00e+003.1491792
GO:0035335peptidyl-tyrosine dephosphorylation1.09e-011.00e+003.1181294
GO:0001649osteoblast differentiation1.10e-011.00e+003.1031695
GO:0001764neuron migration1.11e-011.00e+003.0881296
GO:0006468protein phosphorylation1.11e-011.00e+001.805210467
GO:0006364rRNA processing1.11e-011.00e+003.0881596
GO:0005178integrin binding1.12e-011.00e+003.0731297
GO:0071456cellular response to hypoxia1.14e-011.00e+003.0581498
GO:0014069postsynaptic density1.22e-011.00e+002.94511106
GO:0005938cell cortex1.25e-011.00e+002.90413109
GO:0042127regulation of cell proliferation1.28e-011.00e+002.87814111
GO:0015630microtubule cytoskeleton1.29e-011.00e+002.86515112
GO:0048015phosphatidylinositol-mediated signaling1.32e-011.00e+002.82713115
GO:0005635nuclear envelope1.33e-011.00e+002.81516116
GO:0048471perinuclear region of cytoplasm1.33e-011.00e+001.642212523
GO:0072562blood microparticle1.33e-011.00e+002.81514116
GO:0006325chromatin organization1.40e-011.00e+002.73014123
GO:0051092positive regulation of NF-kappaB transcription factor activity1.43e-011.00e+002.70714125
GO:0007219Notch signaling pathway1.43e-011.00e+002.70714125
GO:0008201heparin binding1.45e-011.00e+002.68412127
GO:0006511ubiquitin-dependent protein catabolic process1.45e-011.00e+002.68415127
GO:0030036actin cytoskeleton organization1.47e-011.00e+002.66115129
GO:0016477cell migration1.49e-011.00e+002.63916131
GO:0009615response to virus1.50e-011.00e+002.62816132
GO:0000790nuclear chromatin1.51e-011.00e+002.61717133
GO:0006644phospholipid metabolic process1.55e-011.00e+002.57415137
GO:0016887ATPase activity1.63e-011.00e+002.50317144
GO:0061024membrane organization1.65e-011.00e+002.48315146
GO:0006457protein folding1.68e-011.00e+002.45318149
GO:0008017microtubule binding1.69e-011.00e+002.44417150
GO:0045087innate immune response1.73e-011.00e+001.406220616
GO:0006974cellular response to DNA damage stimulus1.77e-011.00e+002.36918158
GO:0008543fibroblast growth factor receptor signaling pathway1.78e-011.00e+002.36014159
GO:0045121membrane raft1.80e-011.00e+002.34218161
GO:0034220ion transmembrane transport1.86e-011.00e+002.28912167
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding1.87e-011.00e+002.28015168
GO:0006397mRNA processing1.88e-011.00e+002.27213169
GO:0038095Fc-epsilon receptor signaling pathway1.90e-011.00e+002.25517171
GO:0016607nuclear speck1.94e-011.00e+002.22114175
GO:0031965nuclear membrane1.95e-011.00e+002.21314176
GO:0003714transcription corepressor activity1.98e-011.00e+002.18917179
GO:0032403protein complex binding2.04e-011.00e+002.14117185
GO:0007173epidermal growth factor receptor signaling pathway2.10e-011.00e+002.09514191
GO:0003924GTPase activity2.22e-011.00e+002.00719203
GO:0006184GTP catabolic process2.38e-011.00e+001.89119220
GO:0007067mitotic nuclear division2.48e-011.00e+001.821113231
GO:0008380RNA splicing2.49e-011.00e+001.815113232
GO:0004842ubiquitin-protein transferase activity2.71e-011.00e+001.67314256
GO:0006281DNA repair2.78e-011.00e+001.628122264
GO:0048011neurotrophin TRK receptor signaling pathway2.86e-011.00e+001.58016273
GO:0043065positive regulation of apoptotic process2.87e-011.00e+001.57418274
GO:0006357regulation of transcription from RNA polymerase II promoter2.88e-011.00e+001.56916275
GO:0042493response to drug3.00e-011.00e+001.503111288
GO:0016567protein ubiquitination3.09e-011.00e+001.44915299
GO:0043234protein complex3.10e-011.00e+001.444117300
GO:0006200ATP catabolic process3.13e-011.00e+001.429114303
GO:0005856cytoskeleton3.20e-011.00e+001.39218311
GO:0035556intracellular signal transduction3.25e-011.00e+001.36416317
GO:0030154cell differentiation3.31e-011.00e+001.32815325
GO:0005525GTP binding3.34e-011.00e+001.315111328
GO:0007268synaptic transmission3.54e-011.00e+001.20912353
GO:0005739mitochondrion3.70e-011.00e+000.6422241046
GO:0007155cell adhesion3.79e-011.00e+001.08818384
GO:0006508proteolysis3.99e-011.00e+000.99319410
GO:0007596blood coagulation4.39e-011.00e+000.815114464
GO:0005886plasma membrane4.67e-011.00e+000.2044382834
GO:0055085transmembrane transport4.73e-011.00e+000.66718514
GO:0042803protein homodimerization activity5.38e-011.00e+000.403111617
GO:0005789endoplasmic reticulum membrane5.49e-011.00e+000.360110636
GO:0045944positive regulation of transcription from RNA polymerase II promoter6.39e-011.00e+000.009119811
GO:0005615extracellular space7.22e-011.00e+00-0.3081171010
GO:0008270zinc ion binding7.42e-011.00e+00-0.3871121067
GO:0006351transcription, DNA-templated8.71e-011.00e+00-0.9581251585