| GO:0005164 | tumor necrosis factor receptor binding | 3 | 30 | 
| GO:0005515 | protein binding | 172 | 6127 | 
| GO:0005737 | cytoplasm | 98 | 3976 | 
| GO:0008270 | zinc ion binding | 12 | 1067 | 
| GO:0048471 | perinuclear region of cytoplasm | 12 | 523 | 
| GO:0031625 | ubiquitin protein ligase binding | 13 | 180 | 
| GO:0090073 | positive regulation of protein homodimerization activity | 1 | 7 | 
| GO:0042981 | regulation of apoptotic process | 26 | 151 | 
| GO:0030323 | respiratory tube development | 1 | 4 | 
| GO:0016567 | protein ubiquitination | 5 | 299 | 
| GO:0007585 | respiratory gaseous exchange | 1 | 31 | 
| GO:0019901 | protein kinase binding | 21 | 320 | 
| GO:0005923 | tight junction | 2 | 92 | 
| GO:0007250 | activation of NF-kappaB-inducing kinase activity | 1 | 19 | 
| GO:0005634 | nucleus | 131 | 4828 | 
| GO:0005856 | cytoskeleton | 8 | 311 | 
| GO:0006915 | apoptotic process | 34 | 571 | 
| GO:0046330 | positive regulation of JNK cascade | 1 | 55 | 
| GO:0007165 | signal transduction | 17 | 950 | 
| GO:0003677 | DNA binding | 26 | 1351 | 
| GO:0050699 | WW domain binding | 1 | 21 | 
| GO:0004842 | ubiquitin-protein transferase activity | 4 | 256 | 
| GO:0031996 | thioesterase binding | 2 | 14 | 
| GO:0005886 | plasma membrane | 38 | 2834 | 
| GO:0045860 | positive regulation of protein kinase activity | 1 | 45 |