TNF

Genes (1)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
TNF 7124 110.0210.96798--

Gene info in the NCBI database: TNF

11 meta-subnetworks

Subnetwork ID Size Highlighted genes
meta-reg-snw-55660 25 68
meta-reg-snw-317781 53 94
meta-reg-snw-4522 49 93
meta-reg-snw-1642 11 48
meta-int-snw-7124 11 38
meta-reg-snw-158 15 56
meta-reg-snw-56655 63 99
meta-reg-snw-5686 35 80
meta-reg-snw-10213 44 87
meta-reg-snw-1434 41 87
meta-reg-snw-11277 51 90

Related GO terms (130)

Accession number Name Occurrences in all snw genes Occurrences in all int/reg genes
GO:0005515protein binding1726127
GO:0002740negative regulation of cytokine secretion involved in immune response15
GO:0002439chronic inflammatory response to antigenic stimulus12
GO:0045892negative regulation of transcription, DNA-templated14424
GO:0000187activation of MAPK activity490
GO:0071803positive regulation of podosome assembly15
GO:0001934positive regulation of protein phosphorylation5108
GO:0003009skeletal muscle contraction119
GO:0043122regulation of I-kappaB kinase/NF-kappaB signaling111
GO:0071316cellular response to nicotine18
GO:0051384response to glucocorticoid262
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling3148
GO:0051092positive regulation of NF-kappaB transcription factor activity4125
GO:0031663lipopolysaccharide-mediated signaling pathway129
GO:0060559positive regulation of calcidiol 1-monooxygenase activity13
GO:0005886plasma membrane382834
GO:0000060protein import into nucleus, translocation424
GO:0048566embryonic digestive tract development114
GO:0045760positive regulation of action potential17
GO:0045071negative regulation of viral genome replication134
GO:0043406positive regulation of MAP kinase activity247
GO:0042493response to drug11288
GO:0010888negative regulation of lipid storage27
GO:0048661positive regulation of smooth muscle cell proliferation249
GO:0045840positive regulation of mitosis128
GO:0045080positive regulation of chemokine biosynthetic process19
GO:0001775cell activation17
GO:0044212transcription regulatory region DNA binding6171
GO:0060664epithelial cell proliferation involved in salivary gland morphogenesis17
GO:0010628positive regulation of gene expression4149
GO:0050966detection of mechanical stimulus involved in sensory perception of pain18
GO:0050901leukocyte tethering or rolling115
GO:0051798positive regulation of hair follicle development15
GO:0006954inflammatory response6289
GO:0005615extracellular space171010
GO:0009314response to radiation127
GO:0033138positive regulation of peptidyl-serine phosphorylation361
GO:0031622positive regulation of fever generation25
GO:1990268response to gold nanoparticle12
GO:0009651response to salt stress214
GO:0030316osteoclast differentiation222
GO:2000377regulation of reactive oxygen species metabolic process117
GO:0051222positive regulation of protein transport14
GO:0032741positive regulation of interleukin-18 production13
GO:0060557positive regulation of vitamin D biosynthetic process12
GO:0051897positive regulation of protein kinase B signaling175
GO:0050715positive regulation of cytokine secretion125
GO:0030198extracellular matrix organization3295
GO:0032722positive regulation of chemokine production116
GO:0051023regulation of immunoglobulin secretion15
GO:0043243positive regulation of protein complex disassembly13
GO:0006927transformed cell apoptotic process16
GO:0005164tumor necrosis factor receptor binding330
GO:0050806positive regulation of synaptic transmission112
GO:0050796regulation of insulin secretion282
GO:0032715negative regulation of interleukin-6 production120
GO:0071230cellular response to amino acid stimulus242
GO:0019722calcium-mediated signaling140
GO:0002020protease binding474
GO:0032800receptor biosynthetic process13
GO:0071407cellular response to organic cyclic compound239
GO:0001666response to hypoxia2150
GO:0060693regulation of branching involved in salivary gland morphogenesis14
GO:0000185activation of MAPKKK activity29
GO:2001240negative regulation of extrinsic apoptotic signaling pathway in absence of ligand134
GO:0006006glucose metabolic process4119
GO:0014823response to activity132
GO:0042802identical protein binding18491
GO:0008625extrinsic apoptotic signaling pathway via death domain receptors234
GO:0009615response to virus6132
GO:0051044positive regulation of membrane protein ectodomain proteolysis115
GO:0005576extracellular region91049
GO:0045672positive regulation of osteoclast differentiation119
GO:0043280positive regulation of cysteine-type endopeptidase activity involved in apoptotic process136
GO:0045429positive regulation of nitric oxide biosynthetic process335
GO:0043242negative regulation of protein complex disassembly14
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activity593
GO:0070374positive regulation of ERK1 and ERK2 cascade1110
GO:0043491protein kinase B signaling132
GO:0009986cell surface9422
GO:0045893positive regulation of transcription, DNA-templated17487
GO:0051533positive regulation of NFAT protein import into nucleus14
GO:0008285negative regulation of cell proliferation11367
GO:0034116positive regulation of heterotypic cell-cell adhesion19
GO:0097190apoptotic signaling pathway4116
GO:0031334positive regulation of protein complex assembly214
GO:0001891phagocytic cup216
GO:0043507positive regulation of JUN kinase activity228
GO:0010629negative regulation of gene expression180
GO:0097527necroptotic signaling pathway16
GO:0000165MAPK cascade272
GO:0045121membrane raft8161
GO:0045994positive regulation of translational initiation by iron11
GO:0045599negative regulation of fat cell differentiation235
GO:0033209tumor necrosis factor-mediated signaling pathway128
GO:0045944positive regulation of transcription from RNA polymerase II promoter19811
GO:0006915apoptotic process34571
GO:0030730sequestering of triglyceride13
GO:2000343positive regulation of chemokine (C-X-C motif) ligand 2 production14
GO:0005125cytokine activity1146
GO:0071677positive regulation of mononuclear cell migration13
GO:0043068positive regulation of programmed cell death18
GO:0050995negative regulation of lipid catabolic process113
GO:0050830defense response to Gram-positive bacterium149
GO:0008630intrinsic apoptotic signaling pathway in response to DNA damage249
GO:0005887integral component of plasma membrane7961
GO:0055037recycling endosome273
GO:0044130negative regulation of growth of symbiont in host117
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process677
GO:0032755positive regulation of interleukin-6 production236
GO:0009887organ morphogenesis289
GO:0007254JNK cascade251
GO:0002037negative regulation of L-glutamate transport11
GO:0006959humoral immune response152
GO:0097191extrinsic apoptotic signaling pathway238
GO:0009897external side of plasma membrane4183
GO:0043065positive regulation of apoptotic process8274
GO:0043525positive regulation of neuron apoptotic process246
GO:0001819positive regulation of cytokine production119
GO:0045668negative regulation of osteoblast differentiation137
GO:0002876positive regulation of chronic inflammatory response to antigenic stimulus12
GO:0042346positive regulation of NF-kappaB import into nucleus218
GO:0010693negative regulation of alkaline phosphatase activity14
GO:0000122negative regulation of transcription from RNA polymerase II promoter12589
GO:0046325negative regulation of glucose import18
GO:0032729positive regulation of interferon-gamma production239
GO:0045416positive regulation of interleukin-8 biosynthetic process18
GO:2000010positive regulation of protein localization to cell surface28
GO:0002925positive regulation of humoral immune response mediated by circulating immunoglobulin15
GO:0061048negative regulation of branching involved in lung morphogenesis11