int-snw-6638

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.956	2.43e-16	1.55e-03	2.85e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-6638 subnetwork

Genes (6)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
ACTB	60	167	1.153	1.151	587	Yes	-
ACO2	50	50	1.000	1.076	191	Yes	-
HSPD1	3329	35	0.913	1.035	286	Yes	-
FBL	2091	7	0.839	1.151	65	Yes	-
[ SNRPN ]	6638	1	0.505	0.956	42	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-

Interactions (7)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
FBL	2091	SNRPN	6638	pp	--	int.I2D: HPRD; int.HPRD: in vitro
HSPD1	3329	RPSA	3921	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
ACO2	50	HSPD1	3329	pp	--	int.I2D: IntAct_Yeast
ACTB	60	FBL	2091	pp	--	int.I2D: MINT
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
HSPD1	3329	SNRPN	6638	pp	--	int.I2D: BioGrid_Fly, BIND_Fly, IntAct_Fly, MINT_Fly
ACTB	60	HSPD1	3329	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastLow

Related GO terms (140)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:1990259	histone-glutamine methyltransferase activity	4.16e-04	1.00e+00	11.231	1	1	1
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	4.16e-04	1.00e+00	11.231	1	1	1
GO:1990258	histone glutamine methylation	4.16e-04	1.00e+00	11.231	1	1	1
GO:0048291	isotype switching to IgG isotypes	4.16e-04	1.00e+00	11.231	1	1	1
GO:0016074	snoRNA metabolic process	4.16e-04	1.00e+00	11.231	1	1	1
GO:0002368	B cell cytokine production	4.16e-04	1.00e+00	11.231	1	1	1
GO:0051538	3 iron, 4 sulfur cluster binding	8.32e-04	1.00e+00	10.231	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	8.32e-04	1.00e+00	10.231	1	1	2
GO:0003994	aconitate hydratase activity	8.32e-04	1.00e+00	10.231	1	1	2
GO:0005055	laminin receptor activity	8.32e-04	1.00e+00	10.231	1	1	2
GO:0006407	rRNA export from nucleus	8.32e-04	1.00e+00	10.231	1	1	2
GO:0006458	'de novo' protein folding	1.25e-03	1.00e+00	9.646	1	1	3
GO:0030135	coated vesicle	1.25e-03	1.00e+00	9.646	1	1	3
GO:0005686	U2 snRNP	1.66e-03	1.00e+00	9.231	1	1	4
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.66e-03	1.00e+00	9.231	1	1	4
GO:0030686	90S preribosome	1.66e-03	1.00e+00	9.231	1	1	4
GO:0001652	granular component	1.66e-03	1.00e+00	9.231	1	1	4
GO:0031428	box C/D snoRNP complex	1.66e-03	1.00e+00	9.231	1	1	4
GO:0046696	lipopolysaccharide receptor complex	2.08e-03	1.00e+00	8.909	1	1	5
GO:0006102	isocitrate metabolic process	2.08e-03	1.00e+00	8.909	1	1	5
GO:0016020	membrane	2.27e-03	1.00e+00	2.516	4	90	1681
GO:0003688	DNA replication origin binding	2.49e-03	1.00e+00	8.646	1	2	6
GO:0030957	Tat protein binding	2.49e-03	1.00e+00	8.646	1	3	6
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	2.49e-03	1.00e+00	8.646	1	1	6
GO:0006101	citrate metabolic process	2.49e-03	1.00e+00	8.646	1	1	6
GO:0000028	ribosomal small subunit assembly	2.91e-03	1.00e+00	8.424	1	1	7
GO:0070688	MLL5-L complex	3.32e-03	1.00e+00	8.231	1	1	8
GO:0051604	protein maturation	3.32e-03	1.00e+00	8.231	1	1	8
GO:0005759	mitochondrial matrix	3.58e-03	1.00e+00	4.398	2	14	228
GO:0043032	positive regulation of macrophage activation	4.15e-03	1.00e+00	7.909	1	1	10
GO:0032727	positive regulation of interferon-alpha production	4.57e-03	1.00e+00	7.772	1	1	11
GO:0001530	lipopolysaccharide binding	5.40e-03	1.00e+00	7.531	1	3	13
GO:0051131	chaperone-mediated protein complex assembly	5.40e-03	1.00e+00	7.531	1	1	13
GO:0035267	NuA4 histone acetyltransferase complex	5.81e-03	1.00e+00	7.424	1	4	14
GO:0005685	U1 snRNP	5.81e-03	1.00e+00	7.424	1	1	14
GO:0043234	protein complex	5.92e-03	1.00e+00	4.027	2	18	295
GO:0042026	protein refolding	6.22e-03	1.00e+00	7.324	1	2	15
GO:0044822	poly(A) RNA binding	6.62e-03	1.00e+00	2.772	3	49	1056
GO:0050998	nitric-oxide synthase binding	6.64e-03	1.00e+00	7.231	1	1	16
GO:0050870	positive regulation of T cell activation	7.05e-03	1.00e+00	7.144	1	1	17
GO:0030532	small nuclear ribonucleoprotein complex	7.47e-03	1.00e+00	7.061	1	1	18
GO:0032733	positive regulation of interleukin-10 production	7.88e-03	1.00e+00	6.983	1	1	19
GO:0003723	RNA binding	7.89e-03	1.00e+00	3.813	2	20	342
GO:0070062	extracellular vesicular exosome	8.64e-03	1.00e+00	2.002	4	104	2400
GO:0042100	B cell proliferation	8.71e-03	1.00e+00	6.839	1	1	21
GO:0030863	cortical cytoskeleton	9.12e-03	1.00e+00	6.772	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	9.12e-03	1.00e+00	6.772	1	4	22
GO:0043044	ATP-dependent chromatin remodeling	9.53e-03	1.00e+00	6.708	1	4	23
GO:0043236	laminin binding	9.53e-03	1.00e+00	6.708	1	1	23
GO:0042113	B cell activation	1.04e-02	1.00e+00	6.587	1	2	25
GO:0032735	positive regulation of interleukin-12 production	1.04e-02	1.00e+00	6.587	1	1	25
GO:0043022	ribosome binding	1.12e-02	1.00e+00	6.476	1	3	27
GO:0031492	nucleosomal DNA binding	1.12e-02	1.00e+00	6.476	1	4	27
GO:0006099	tricarboxylic acid cycle	1.16e-02	1.00e+00	6.424	1	4	28
GO:0019894	kinesin binding	1.16e-02	1.00e+00	6.424	1	1	28
GO:0001895	retina homeostasis	1.41e-02	1.00e+00	6.144	1	1	34
GO:0008033	tRNA processing	1.41e-02	1.00e+00	6.144	1	1	34
GO:0051539	4 iron, 4 sulfur cluster binding	1.45e-02	1.00e+00	6.102	1	3	35
GO:0009725	response to hormone	1.45e-02	1.00e+00	6.102	1	1	35
GO:0044267	cellular protein metabolic process	1.48e-02	1.00e+00	3.342	2	29	474
GO:0034332	adherens junction organization	1.49e-02	1.00e+00	6.061	1	1	36
GO:0032755	positive regulation of interleukin-6 production	1.49e-02	1.00e+00	6.061	1	2	36
GO:0051084	'de novo' posttranslational protein folding	1.53e-02	1.00e+00	6.022	1	4	37
GO:0070527	platelet aggregation	1.57e-02	1.00e+00	5.983	1	2	38
GO:0032729	positive regulation of interferon-gamma production	1.61e-02	1.00e+00	5.946	1	2	39
GO:0022627	cytosolic small ribosomal subunit	1.61e-02	1.00e+00	5.946	1	4	39
GO:0042110	T cell activation	1.73e-02	1.00e+00	5.839	1	3	42
GO:0021762	substantia nigra development	1.82e-02	1.00e+00	5.772	1	2	44
GO:0015030	Cajal body	1.82e-02	1.00e+00	5.772	1	3	44
GO:0016032	viral process	1.86e-02	1.00e+00	3.170	2	55	534
GO:0006091	generation of precursor metabolites and energy	2.06e-02	1.00e+00	5.587	1	3	50
GO:0006986	response to unfolded protein	2.06e-02	1.00e+00	5.587	1	2	50
GO:0005905	coated pit	2.06e-02	1.00e+00	5.587	1	3	50
GO:0003725	double-stranded RNA binding	2.14e-02	1.00e+00	5.531	1	5	52
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.19e-02	1.00e+00	5.503	1	5	53
GO:0045216	cell-cell junction organization	2.23e-02	1.00e+00	5.476	1	2	54
GO:0002039	p53 binding	2.27e-02	1.00e+00	5.450	1	7	55
GO:0051087	chaperone binding	2.43e-02	1.00e+00	5.348	1	6	59
GO:0030141	secretory granule	2.55e-02	1.00e+00	5.277	1	2	62
GO:0034329	cell junction assembly	2.80e-02	1.00e+00	5.144	1	1	68
GO:0003697	single-stranded DNA binding	2.80e-02	1.00e+00	5.144	1	5	68
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	3.04e-02	1.00e+00	5.022	1	6	74
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	3.16e-02	1.00e+00	4.964	1	7	77
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	3.28e-02	1.00e+00	4.909	1	3	80
GO:0019083	viral transcription	3.32e-02	1.00e+00	4.891	1	10	81
GO:0005681	spliceosomal complex	3.40e-02	1.00e+00	4.856	1	4	83
GO:0006415	translational termination	3.57e-02	1.00e+00	4.788	1	10	87
GO:0050821	protein stabilization	3.61e-02	1.00e+00	4.772	1	2	88
GO:0006928	cellular component movement	3.73e-02	1.00e+00	4.723	1	7	91
GO:0005200	structural constituent of cytoskeleton	3.73e-02	1.00e+00	4.723	1	8	91
GO:0001649	osteoblast differentiation	3.77e-02	1.00e+00	4.708	1	6	92
GO:0006414	translational elongation	3.81e-02	1.00e+00	4.692	1	13	93
GO:0051082	unfolded protein binding	3.81e-02	1.00e+00	4.692	1	5	93
GO:0006364	rRNA processing	3.85e-02	1.00e+00	4.677	1	6	94
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	4.25e-02	1.00e+00	4.531	1	10	104
GO:0014069	postsynaptic density	4.29e-02	1.00e+00	4.517	1	3	105
GO:0005506	iron ion binding	4.29e-02	1.00e+00	4.517	1	4	105
GO:0072562	blood microparticle	4.53e-02	1.00e+00	4.437	1	3	111
GO:0030529	ribonucleoprotein complex	4.57e-02	1.00e+00	4.424	1	8	112
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	4.65e-02	1.00e+00	4.398	1	11	114
GO:0019058	viral life cycle	4.69e-02	1.00e+00	4.386	1	13	115
GO:0044237	cellular metabolic process	4.77e-02	1.00e+00	4.361	1	5	117
GO:0006325	chromatin organization	4.81e-02	1.00e+00	4.348	1	5	118
GO:0005515	protein binding	4.97e-02	1.00e+00	0.997	5	184	6024
GO:0000790	nuclear chromatin	5.25e-02	1.00e+00	4.220	1	9	129
GO:0006413	translational initiation	5.33e-02	1.00e+00	4.198	1	17	131
GO:0005615	extracellular space	5.52e-02	1.00e+00	2.329	2	17	957
GO:0003735	structural constituent of ribosome	5.57e-02	1.00e+00	4.133	1	10	137
GO:0016887	ATPase activity	5.69e-02	1.00e+00	4.102	1	7	140
GO:0006457	protein folding	5.80e-02	1.00e+00	4.071	1	7	143
GO:0061024	membrane organization	5.88e-02	1.00e+00	4.051	1	7	145
GO:0005739	mitochondrion	5.95e-02	1.00e+00	2.268	2	28	998
GO:0005769	early endosome	6.16e-02	1.00e+00	3.983	1	2	152
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	6.67e-02	1.00e+00	3.865	1	7	165
GO:0030424	axon	6.71e-02	1.00e+00	3.856	1	4	166
GO:0005829	cytosol	6.86e-02	1.00e+00	1.531	3	132	2496
GO:0016071	mRNA metabolic process	8.93e-02	1.00e+00	3.430	1	31	223
GO:0008380	RNA splicing	9.12e-02	1.00e+00	3.398	1	11	228
GO:0006412	translation	9.20e-02	1.00e+00	3.386	1	20	230
GO:0005524	ATP binding	9.51e-02	1.00e+00	1.889	2	60	1298
GO:0016070	RNA metabolic process	9.85e-02	1.00e+00	3.283	1	32	247
GO:0043065	positive regulation of apoptotic process	1.06e-01	1.00e+00	3.165	1	10	268
GO:0005743	mitochondrial inner membrane	1.10e-01	1.00e+00	3.117	1	8	277
GO:0005856	cytoskeleton	1.15e-01	1.00e+00	3.046	1	12	291
GO:0006200	ATP catabolic process	1.16e-01	1.00e+00	3.041	1	15	292
GO:0019901	protein kinase binding	1.25e-01	1.00e+00	2.923	1	21	317
GO:0007411	axon guidance	1.26e-01	1.00e+00	2.914	1	13	319
GO:0005925	focal adhesion	1.43e-01	1.00e+00	2.715	1	19	366
GO:0007155	cell adhesion	1.44e-01	1.00e+00	2.704	1	6	369
GO:0009986	cell surface	1.56e-01	1.00e+00	2.580	1	11	402
GO:0043066	negative regulation of apoptotic process	1.64e-01	1.00e+00	2.503	1	31	424
GO:0007596	blood coagulation	1.75e-01	1.00e+00	2.401	1	18	455
GO:0005737	cytoplasm	1.87e-01	1.00e+00	0.937	3	110	3767
GO:0045087	innate immune response	2.24e-01	1.00e+00	2.012	1	24	596
GO:0010467	gene expression	2.48e-01	1.00e+00	1.845	1	59	669
GO:0005634	nucleus	2.86e-01	1.00e+00	0.662	3	136	4559
GO:0005886	plasma membrane	2.93e-01	1.00e+00	0.897	2	45	2582
GO:0005654	nucleoplasm	3.74e-01	1.00e+00	1.152	1	76	1082
GO:0044281	small molecule metabolic process	4.09e-01	1.00e+00	0.989	1	58	1211
GO:0005730	nucleolus	5.16e-01	1.00e+00	0.551	1	69	1641

Wolf-ratios-Mammosphere-Adherent

int-snw-6638

Statistics

Genes (6)

Interactions (7)

Related GO terms (140)