int-snw-6135

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	1.017	7.56e-19	3.62e-04	9.49e-03

wolf-screen-ratio-mammosphere-adherent-int-snw-6135 subnetwork

Genes (7)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
ACTB	60	167	1.153	1.151	587	Yes	-
RPS11	6205	36	0.993	1.113	175	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-
RPL14	9045	42	1.250	1.113	143	Yes	-
[ RPL11 ]	6135	9	0.718	1.017	200	Yes	-
RPS3A	6189	11	0.835	1.069	166	Yes	-
RPL6	6128	11	0.844	1.113	164	Yes	-

Interactions (15)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
RPL6	6128	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
RPSA	3921	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
RPS3A	6189	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
RPL6	6128	RPS3A	6189	pp	--	int.I2D: BioGrid_Yeast
RPL11	6135	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
RPS3A	6189	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
RPL6	6128	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
RPL11	6135	RPS3A	6189	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RPS3A	6189	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
RPL6	6128	RPL11	6135	pp	--	int.I2D: BioGrid_Yeast
RPL11	6135	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
RPS11	6205	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RPL6	6128	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RPL11	6135	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct

Related GO terms (86)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0019083	viral transcription	1.81e-13	2.61e-09	7.254	6	10	81
GO:0006415	translational termination	2.82e-13	4.06e-09	7.151	6	10	87
GO:0006414	translational elongation	4.25e-13	6.13e-09	7.055	6	13	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	8.45e-13	1.22e-08	6.893	6	10	104
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.49e-12	2.14e-08	6.761	6	11	114
GO:0019058	viral life cycle	1.57e-12	2.26e-08	6.748	6	13	115
GO:0006413	translational initiation	3.48e-12	5.01e-08	6.560	6	17	131
GO:0003735	structural constituent of ribosome	4.57e-12	6.59e-08	6.496	6	10	137
GO:0044267	cellular protein metabolic process	3.97e-11	5.72e-07	4.927	7	29	474
GO:0016071	mRNA metabolic process	8.83e-11	1.27e-06	5.793	6	31	223
GO:0006412	translation	1.06e-10	1.54e-06	5.748	6	20	230
GO:0016070	RNA metabolic process	1.64e-10	2.36e-06	5.645	6	32	247
GO:0016032	viral process	1.70e-08	2.45e-04	4.533	6	55	534
GO:0010467	gene expression	6.55e-08	9.45e-04	4.208	6	59	669
GO:0022627	cytosolic small ribosomal subunit	6.35e-07	9.16e-03	7.308	3	4	39
GO:0044822	poly(A) RNA binding	9.98e-07	1.44e-02	3.549	6	49	1056
GO:0022625	cytosolic large ribosomal subunit	1.28e-06	1.84e-02	6.979	3	6	49
GO:0005829	cytosol	4.62e-06	6.66e-02	2.531	7	132	2496
GO:0003723	RNA binding	1.03e-05	1.48e-01	4.591	4	20	342
GO:0005925	focal adhesion	1.34e-05	1.94e-01	4.493	4	19	366
GO:0016020	membrane	1.57e-05	2.26e-01	2.879	6	90	1681
GO:0042273	ribosomal large subunit biogenesis	1.57e-05	2.27e-01	8.308	2	4	13
GO:0036464	cytoplasmic ribonucleoprotein granule	4.64e-05	6.70e-01	7.549	2	4	22
GO:0019843	rRNA binding	7.05e-05	1.00e+00	7.254	2	3	27
GO:0070062	extracellular vesicular exosome	1.27e-04	1.00e+00	2.365	6	104	2400
GO:0006364	rRNA processing	8.64e-04	1.00e+00	5.454	2	6	94
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	9.70e-04	1.00e+00	10.009	1	1	2
GO:0005055	laminin receptor activity	9.70e-04	1.00e+00	10.009	1	1	2
GO:0006407	rRNA export from nucleus	9.70e-04	1.00e+00	10.009	1	1	2
GO:0030529	ribonucleoprotein complex	1.22e-03	1.00e+00	5.201	2	8	112
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.94e-03	1.00e+00	9.009	1	1	4
GO:0030686	90S preribosome	1.94e-03	1.00e+00	9.009	1	1	4
GO:0002181	cytoplasmic translation	2.91e-03	1.00e+00	8.424	1	1	6
GO:0030957	Tat protein binding	2.91e-03	1.00e+00	8.424	1	3	6
GO:0000028	ribosomal small subunit assembly	3.39e-03	1.00e+00	8.201	1	1	7
GO:0070688	MLL5-L complex	3.88e-03	1.00e+00	8.009	1	1	8
GO:0035267	NuA4 histone acetyltransferase complex	6.78e-03	1.00e+00	7.201	1	4	14
GO:0050998	nitric-oxide synthase binding	7.74e-03	1.00e+00	7.009	1	1	16
GO:0030863	cortical cytoskeleton	1.06e-02	1.00e+00	6.549	1	1	22
GO:0043044	ATP-dependent chromatin remodeling	1.11e-02	1.00e+00	6.485	1	4	23
GO:0043236	laminin binding	1.11e-02	1.00e+00	6.485	1	1	23
GO:0031492	nucleosomal DNA binding	1.30e-02	1.00e+00	6.254	1	4	27
GO:0043022	ribosome binding	1.30e-02	1.00e+00	6.254	1	3	27
GO:0019894	kinesin binding	1.35e-02	1.00e+00	6.201	1	1	28
GO:0034504	protein localization to nucleus	1.35e-02	1.00e+00	6.201	1	2	28
GO:0001895	retina homeostasis	1.64e-02	1.00e+00	5.921	1	1	34
GO:0006605	protein targeting	1.69e-02	1.00e+00	5.879	1	2	35
GO:0034332	adherens junction organization	1.73e-02	1.00e+00	5.839	1	1	36
GO:0051084	'de novo' posttranslational protein folding	1.78e-02	1.00e+00	5.799	1	4	37
GO:0070527	platelet aggregation	1.83e-02	1.00e+00	5.761	1	2	38
GO:0021762	substantia nigra development	2.12e-02	1.00e+00	5.549	1	2	44
GO:0005515	protein binding	2.38e-02	1.00e+00	1.037	6	184	6024
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.54e-02	1.00e+00	5.281	1	5	53
GO:0045216	cell-cell junction organization	2.59e-02	1.00e+00	5.254	1	2	54
GO:0005840	ribosome	2.78e-02	1.00e+00	5.151	1	1	58
GO:0034329	cell junction assembly	3.25e-02	1.00e+00	4.921	1	1	68
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	3.54e-02	1.00e+00	4.799	1	6	74
GO:0005200	structural constituent of cytoskeleton	4.33e-02	1.00e+00	4.501	1	8	91
GO:0006928	cellular component movement	4.33e-02	1.00e+00	4.501	1	7	91
GO:0001649	osteoblast differentiation	4.38e-02	1.00e+00	4.485	1	6	92
GO:0014069	postsynaptic density	4.99e-02	1.00e+00	4.294	1	3	105
GO:0072562	blood microparticle	5.27e-02	1.00e+00	4.214	1	3	111
GO:0006325	chromatin organization	5.59e-02	1.00e+00	4.126	1	5	118
GO:0000790	nuclear chromatin	6.10e-02	1.00e+00	3.998	1	9	129
GO:0006457	protein folding	6.74e-02	1.00e+00	3.849	1	7	143
GO:0061024	membrane organization	6.83e-02	1.00e+00	3.829	1	7	145
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	7.74e-02	1.00e+00	3.642	1	7	165
GO:0030424	axon	7.79e-02	1.00e+00	3.634	1	4	166
GO:0005737	cytoplasm	8.13e-02	1.00e+00	1.130	4	110	3767
GO:0005856	cytoskeleton	1.33e-01	1.00e+00	2.824	1	12	291
GO:0043234	protein complex	1.35e-01	1.00e+00	2.804	1	18	295
GO:0030154	cell differentiation	1.37e-01	1.00e+00	2.775	1	5	301
GO:0019901	protein kinase binding	1.44e-01	1.00e+00	2.700	1	21	317
GO:0007411	axon guidance	1.45e-01	1.00e+00	2.691	1	13	319
GO:0007155	cell adhesion	1.66e-01	1.00e+00	2.481	1	6	369
GO:0005730	nucleolus	1.85e-01	1.00e+00	1.328	2	69	1641
GO:0043066	negative regulation of apoptotic process	1.89e-01	1.00e+00	2.281	1	31	424
GO:0007596	blood coagulation	2.01e-01	1.00e+00	2.179	1	18	455
GO:0045087	innate immune response	2.56e-01	1.00e+00	1.790	1	24	596
GO:0005615	extracellular space	3.82e-01	1.00e+00	1.106	1	17	957
GO:0005634	nucleus	3.90e-01	1.00e+00	0.439	3	136	4559
GO:0006355	regulation of transcription, DNA-templated	3.94e-01	1.00e+00	1.047	1	18	997
GO:0005654	nucleoplasm	4.21e-01	1.00e+00	0.929	1	76	1082
GO:0003677	DNA binding	4.61e-01	1.00e+00	0.758	1	28	1218
GO:0005524	ATP binding	4.83e-01	1.00e+00	0.667	1	60	1298
GO:0005886	plasma membrane	7.49e-01	1.00e+00	-0.326	1	45	2582

Wolf-ratios-Mammosphere-Adherent

int-snw-6135

Statistics

Genes (7)

Interactions (15)

Related GO terms (86)