int-snw-3692

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.955	2.67e-16	1.59e-03	2.90e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-3692 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
ACO2	50	50	1.000	1.076	191	Yes	-
RSL24D1	51187	36	1.300	1.020	59	Yes	-
[ EIF6 ]	3692	14	0.700	1.013	267	Yes	-
RPL6	6128	11	0.844	1.113	164	Yes	-
OGDH	4967	13	0.847	1.076	113	Yes	-
PFDN2	5202	2	0.837	0.955	43	Yes	-
HSPD1	3329	35	0.913	1.035	286	Yes	-
PGD	5226	75	1.201	1.106	138	Yes	-

Interactions (13)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
HSPD1	3329	EIF6	3692	pp	--	int.I2D: BioGrid_Yeast
OGDH	4967	RPL6	6128	pp	--	int.I2D: IntAct_Yeast
EIF6	3692	RSL24D1	51187	pp	--	int.I2D: BioGrid_Yeast, YeastLow
OGDH	4967	PGD	5226	pp	--	int.I2D: YeastLow
EIF6	3692	PGD	5226	pp	--	int.I2D: YeastLow
EIF6	3692	RPL6	6128	pp	--	int.I2D: BioGrid, HPRD, StelzlMedium; int.HPRD: yeast 2-hybrid
EIF6	3692	PFDN2	5202	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
ACO2	50	HSPD1	3329	pp	--	int.I2D: IntAct_Yeast
EIF6	3692	OGDH	4967	pp	--	int.I2D: YeastLow
HSPD1	3329	OGDH	4967	pp	--	int.I2D: YeastLow
ACO2	50	OGDH	4967	pp	--	int.I2D: YeastLow
ACO2	50	EIF6	3692	pp	--	int.I2D: YeastLow
ACO2	50	PGD	5226	pp	--	int.I2D: YeastLow

Related GO terms (124)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006099	tricarboxylic acid cycle	1.01e-04	1.00e+00	7.009	2	4	28
GO:0005759	mitochondrial matrix	2.06e-04	1.00e+00	4.568	3	14	228
GO:0006091	generation of precursor metabolites and energy	3.25e-04	1.00e+00	6.172	2	3	50
GO:0051087	chaperone binding	4.53e-04	1.00e+00	5.933	2	6	59
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	5.55e-04	1.00e+00	10.816	1	1	1
GO:0048291	isotype switching to IgG isotypes	5.55e-04	1.00e+00	10.816	1	1	1
GO:0019521	D-gluconate metabolic process	5.55e-04	1.00e+00	10.816	1	1	1
GO:0000054	ribosomal subunit export from nucleus	5.55e-04	1.00e+00	10.816	1	1	1
GO:0034602	oxoglutarate dehydrogenase (NAD+) activity	5.55e-04	1.00e+00	10.816	1	1	1
GO:0002368	B cell cytokine production	5.55e-04	1.00e+00	10.816	1	1	1
GO:0019322	pentose biosynthetic process	1.11e-03	1.00e+00	9.816	1	2	2
GO:0003994	aconitate hydratase activity	1.11e-03	1.00e+00	9.816	1	1	2
GO:0061034	olfactory bulb mitral cell layer development	1.11e-03	1.00e+00	9.816	1	1	2
GO:0045252	oxoglutarate dehydrogenase complex	1.11e-03	1.00e+00	9.816	1	2	2
GO:0051538	3 iron, 4 sulfur cluster binding	1.11e-03	1.00e+00	9.816	1	1	2
GO:0051082	unfolded protein binding	1.12e-03	1.00e+00	5.277	2	5	93
GO:0005739	mitochondrion	1.27e-03	1.00e+00	2.853	4	28	998
GO:0009051	pentose-phosphate shunt, oxidative branch	1.66e-03	1.00e+00	9.231	1	2	3
GO:0006458	'de novo' protein folding	1.66e-03	1.00e+00	9.231	1	1	3
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	1.66e-03	1.00e+00	9.231	1	1	3
GO:0030135	coated vesicle	1.66e-03	1.00e+00	9.231	1	1	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	1.66e-03	1.00e+00	9.231	1	1	3
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	1.66e-03	1.00e+00	9.231	1	1	3
GO:0044237	cellular metabolic process	1.77e-03	1.00e+00	4.946	2	5	117
GO:0006413	translational initiation	2.21e-03	1.00e+00	4.783	2	17	131
GO:0006734	NADH metabolic process	2.22e-03	1.00e+00	8.816	1	1	4
GO:0006104	succinyl-CoA metabolic process	2.22e-03	1.00e+00	8.816	1	1	4
GO:0042256	mature ribosome assembly	2.77e-03	1.00e+00	8.494	1	1	5
GO:0005638	lamin filament	2.77e-03	1.00e+00	8.494	1	1	5
GO:0046696	lipopolysaccharide receptor complex	2.77e-03	1.00e+00	8.494	1	1	5
GO:0043023	ribosomal large subunit binding	2.77e-03	1.00e+00	8.494	1	1	5
GO:0006102	isocitrate metabolic process	2.77e-03	1.00e+00	8.494	1	1	5
GO:0030976	thiamine pyrophosphate binding	2.77e-03	1.00e+00	8.494	1	1	5
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	3.32e-03	1.00e+00	8.231	1	1	6
GO:0003688	DNA replication origin binding	3.32e-03	1.00e+00	8.231	1	2	6
GO:0006101	citrate metabolic process	3.32e-03	1.00e+00	8.231	1	1	6
GO:0021860	pyramidal neuron development	3.32e-03	1.00e+00	8.231	1	1	6
GO:0021695	cerebellar cortex development	3.32e-03	1.00e+00	8.231	1	2	6
GO:0006554	lysine catabolic process	4.43e-03	1.00e+00	7.816	1	2	8
GO:0051604	protein maturation	4.43e-03	1.00e+00	7.816	1	1	8
GO:0016272	prefoldin complex	4.98e-03	1.00e+00	7.646	1	1	9
GO:0006098	pentose-phosphate shunt	5.53e-03	1.00e+00	7.494	1	4	10
GO:0043032	positive regulation of macrophage activation	5.53e-03	1.00e+00	7.494	1	1	10
GO:0021756	striatum development	5.53e-03	1.00e+00	7.494	1	1	10
GO:0021794	thalamus development	6.09e-03	1.00e+00	7.357	1	1	11
GO:0032727	positive regulation of interferon-alpha production	6.09e-03	1.00e+00	7.357	1	1	11
GO:0042273	ribosomal large subunit biogenesis	7.19e-03	1.00e+00	7.116	1	4	13
GO:0001530	lipopolysaccharide binding	7.19e-03	1.00e+00	7.116	1	3	13
GO:0051131	chaperone-mediated protein complex assembly	7.19e-03	1.00e+00	7.116	1	1	13
GO:0042026	protein refolding	8.29e-03	1.00e+00	6.909	1	2	15
GO:0006103	2-oxoglutarate metabolic process	8.84e-03	1.00e+00	6.816	1	1	16
GO:0050870	positive regulation of T cell activation	9.39e-03	1.00e+00	6.729	1	1	17
GO:0032733	positive regulation of interleukin-10 production	1.05e-02	1.00e+00	6.568	1	1	19
GO:0042100	B cell proliferation	1.16e-02	1.00e+00	6.424	1	1	21
GO:0036464	cytoplasmic ribonucleoprotein granule	1.21e-02	1.00e+00	6.357	1	4	22
GO:0042113	B cell activation	1.38e-02	1.00e+00	6.172	1	2	25
GO:0032735	positive regulation of interleukin-12 production	1.38e-02	1.00e+00	6.172	1	1	25
GO:0043022	ribosome binding	1.49e-02	1.00e+00	6.061	1	3	27
GO:0050661	NADP binding	1.49e-02	1.00e+00	6.061	1	2	27
GO:0042254	ribosome biogenesis	1.65e-02	1.00e+00	5.909	1	1	30
GO:0031072	heat shock protein binding	1.82e-02	1.00e+00	5.772	1	1	33
GO:0051539	4 iron, 4 sulfur cluster binding	1.93e-02	1.00e+00	5.687	1	3	35
GO:0032755	positive regulation of interleukin-6 production	1.98e-02	1.00e+00	5.646	1	2	36
GO:0051084	'de novo' posttranslational protein folding	2.03e-02	1.00e+00	5.607	1	4	37
GO:0021766	hippocampus development	2.09e-02	1.00e+00	5.568	1	4	38
GO:0006096	glycolytic process	2.09e-02	1.00e+00	5.568	1	4	38
GO:0032729	positive regulation of interferon-gamma production	2.14e-02	1.00e+00	5.531	1	2	39
GO:0042110	T cell activation	2.31e-02	1.00e+00	5.424	1	3	42
GO:0044281	small molecule metabolic process	2.40e-02	1.00e+00	2.159	3	58	1211
GO:0044267	cellular protein metabolic process	2.65e-02	1.00e+00	2.927	2	29	474
GO:0003743	translation initiation factor activity	2.69e-02	1.00e+00	5.201	1	8	49
GO:0022625	cytosolic large ribosomal subunit	2.69e-02	1.00e+00	5.201	1	6	49
GO:0005905	coated pit	2.74e-02	1.00e+00	5.172	1	3	50
GO:0006986	response to unfolded protein	2.74e-02	1.00e+00	5.172	1	2	50
GO:0003725	double-stranded RNA binding	2.85e-02	1.00e+00	5.116	1	5	52
GO:0031966	mitochondrial membrane	3.01e-02	1.00e+00	5.035	1	1	55
GO:0002039	p53 binding	3.01e-02	1.00e+00	5.035	1	7	55
GO:0070062	extracellular vesicular exosome	3.05e-02	1.00e+00	1.587	4	104	2400
GO:0016032	viral process	3.30e-02	1.00e+00	2.755	2	55	534
GO:0030141	secretory granule	3.39e-02	1.00e+00	4.862	1	2	62
GO:0003697	single-stranded DNA binding	3.71e-02	1.00e+00	4.729	1	5	68
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	4.19e-02	1.00e+00	4.549	1	7	77
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	4.35e-02	1.00e+00	4.494	1	3	80
GO:0019083	viral transcription	4.41e-02	1.00e+00	4.476	1	10	81
GO:0006415	translational termination	4.73e-02	1.00e+00	4.373	1	10	87
GO:0050821	protein stabilization	4.78e-02	1.00e+00	4.357	1	2	88
GO:0006414	translational elongation	5.04e-02	1.00e+00	4.277	1	13	93
GO:0005730	nucleolus	5.31e-02	1.00e+00	1.721	3	69	1641
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	5.63e-02	1.00e+00	4.116	1	10	104
GO:0005506	iron ion binding	5.68e-02	1.00e+00	4.102	1	4	105
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	6.15e-02	1.00e+00	3.983	1	11	114
GO:0019058	viral life cycle	6.20e-02	1.00e+00	3.971	1	13	115
GO:0005634	nucleus	7.14e-02	1.00e+00	0.984	5	136	4559
GO:0003735	structural constituent of ribosome	7.35e-02	1.00e+00	3.718	1	10	137
GO:0016887	ATPase activity	7.51e-02	1.00e+00	3.687	1	7	140
GO:0006457	protein folding	7.66e-02	1.00e+00	3.656	1	7	143
GO:0005769	early endosome	8.13e-02	1.00e+00	3.568	1	2	152
GO:0034641	cellular nitrogen compound metabolic process	9.10e-02	1.00e+00	3.398	1	20	171
GO:0044822	poly(A) RNA binding	1.12e-01	1.00e+00	1.772	2	49	1056
GO:0016071	mRNA metabolic process	1.17e-01	1.00e+00	3.015	1	31	223
GO:0006412	translation	1.21e-01	1.00e+00	2.971	1	20	230
GO:0016070	RNA metabolic process	1.29e-01	1.00e+00	2.868	1	32	247
GO:0005975	carbohydrate metabolic process	1.32e-01	1.00e+00	2.833	1	9	253
GO:0043065	positive regulation of apoptotic process	1.39e-01	1.00e+00	2.750	1	10	268
GO:0005743	mitochondrial inner membrane	1.44e-01	1.00e+00	2.702	1	8	277
GO:0005829	cytosol	1.47e-01	1.00e+00	1.116	3	132	2496
GO:0006200	ATP catabolic process	1.51e-01	1.00e+00	2.626	1	15	292
GO:0043234	protein complex	1.52e-01	1.00e+00	2.612	1	18	295
GO:0003723	RNA binding	1.75e-01	1.00e+00	2.398	1	20	342
GO:0005925	focal adhesion	1.86e-01	1.00e+00	2.300	1	19	366
GO:0009986	cell surface	2.02e-01	1.00e+00	2.165	1	11	402
GO:0055114	oxidation-reduction process	2.11e-01	1.00e+00	2.102	1	12	420
GO:0043066	negative regulation of apoptotic process	2.12e-01	1.00e+00	2.088	1	31	424
GO:0016020	membrane	2.37e-01	1.00e+00	1.101	2	90	1681
GO:0005794	Golgi apparatus	2.92e-01	1.00e+00	1.563	1	15	610
GO:0010467	gene expression	3.16e-01	1.00e+00	1.430	1	59	669
GO:0005737	cytoplasm	3.49e-01	1.00e+00	0.522	3	110	3767
GO:0005615	extracellular space	4.23e-01	1.00e+00	0.914	1	17	957
GO:0006355	regulation of transcription, DNA-templated	4.36e-01	1.00e+00	0.855	1	18	997
GO:0003677	DNA binding	5.06e-01	1.00e+00	0.566	1	28	1218
GO:0005524	ATP binding	5.30e-01	1.00e+00	0.474	1	60	1298
GO:0046872	metal ion binding	5.32e-01	1.00e+00	0.464	1	25	1307
GO:0005515	protein binding	7.20e-01	1.00e+00	-0.155	3	184	6024
GO:0005886	plasma membrane	7.94e-01	1.00e+00	-0.518	1	45	2582

Wolf-ratios-Mammosphere-Adherent

int-snw-3692

Statistics

Genes (8)

Interactions (13)

Related GO terms (124)